<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
566
</numberChangedClasses>
<numberNewClasses>
64
</numberNewClasses>
<numberDeletedClasses>
2
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002450</classIRI>
<classLabel>decidua</classLabel>
<deletedAxiom>&apos;decidua&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002402</classIRI>
<classLabel>pleural cavity</classLabel>
<deletedAxiom>&apos;pleural cavity&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103048</classIRI>
<classLabel>tRNA m2A37 methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA m2A37 methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019215</classIRI>
<classLabel>intermediate filament binding</classLabel>
<deletedAxiom>&apos;intermediate filament binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<newAxiom>&apos;intermediate filament binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044101</classIRI>
<classLabel>(R)-citramalyl-CoA lyase activity</classLabel>
<newAxiom>&apos;(R)-citramalyl-CoA lyase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(3R)-citramalyl-CoA(5-)&apos;</newAxiom>
<newAxiom>&apos;(R)-citramalyl-CoA lyase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;acetyl-CoA(4-)&apos;</newAxiom>
<newAxiom>&apos;(R)-citramalyl-CoA lyase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;pyruvate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002323</classIRI>
<classLabel>coelemic cavity lumen</classLabel>
<deletedAxiom>&apos;coelemic cavity lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002339</classIRI>
<classLabel>epithelium of lobar bronchus</classLabel>
<newAxiom>&apos;epithelium of lobar bronchus&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CL_0017000</newAxiom>
<newAxiom>&apos;epithelium of lobar bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;ciliated cell of the bronchus&apos;</newAxiom>
<newAxiom>&apos;epithelium of lobar bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;basal epithelial cell of tracheobronchial tree&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002331</classIRI>
<classLabel>umbilical cord</classLabel>
<deletedAxiom>&apos;umbilical cord&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019178</classIRI>
<classLabel>NADP phosphatase activity</classLabel>
<newAxiom>&apos;NADP phosphatase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NAD(1-)&apos;</newAxiom>
<newAxiom>&apos;NADP phosphatase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</newAxiom>
<newAxiom>&apos;NADP phosphatase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydrogenphosphate&apos;</newAxiom>
<newAxiom>&apos;NADP phosphatase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NADP(3-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002341</classIRI>
<classLabel>epithelium of segmental bronchus</classLabel>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CL_0017000</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;club cell&apos;</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;lung goblet cell&apos;</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some http://purl.obolibrary.org/obo/CL_0002208</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;basal epithelial cell of tracheobronchial tree&apos;</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;lung neuroendocrine cell&apos;</newAxiom>
<newAxiom>&apos;epithelium of segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;ciliated cell of the bronchus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002391</classIRI>
<classLabel>lymph</classLabel>
<deletedAxiom>&apos;lymph&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002397</classIRI>
<classLabel>maxilla</classLabel>
<newAxiom>&apos;maxilla&apos; SubClassOf &apos;overlaps&apos; some http://purl.obolibrary.org/obo/UBERON_7500102</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010723</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to iron</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000016</classIRI>
<classLabel>disposition</classLabel>
<deletedAxiom>&apos;disposition&apos; DisjointWith &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/BFO_0000023</classIRI>
<classLabel>role</classLabel>
<deletedAxiom>&apos;role&apos; SubClassOf &apos;realizable entity&apos;</deletedAxiom>
<deletedAxiom>&apos;role&apos; EquivalentTo &apos;role&apos;</deletedAxiom>
<deletedAxiom>&apos;disposition&apos; DisjointWith &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034722</classIRI>
<classLabel>gamma-glutamyl-peptidase activity</classLabel>
<deletedAxiom>&apos;gamma-glutamyl-peptidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-glutamate(1-)&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-glutamyl-peptidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(6S)-5,6,7,8-tetrahydrofolate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-glutamyl-peptidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-glutamyl-peptidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002203</classIRI>
<classLabel>vasculature of eye</classLabel>
<deletedAxiom>&apos;vasculature of eye&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019050</classIRI>
<classLabel>suppression by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;suppression by symbiont of host apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host apoptotic process&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;negatively regulates&apos; some &apos;apoptotic process&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019051</classIRI>
<classLabel>induction by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;positive regulation by symbiont of host apoptotic process&apos;</deletedAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;positively regulates&apos; some &apos;apoptotic process&apos;</newAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019071</classIRI>
<classLabel>viral DNA cleavage involved in viral genome maturation</classLabel>
<deletedAxiom>&apos;viral DNA cleavage involved in viral genome maturation&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<newAxiom>&apos;viral DNA cleavage involved in viral genome maturation&apos; SubClassOf &apos;DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044081</classIRI>
<classLabel>symbiont-mediated suppression of host nitric oxide-mediated signaling</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host nitric oxide-mediated signaling&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034617</classIRI>
<classLabel>tetrahydrobiopterin binding</classLabel>
<deletedAxiom>&apos;tetrahydrobiopterin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010672</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010673</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010674</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002183</classIRI>
<classLabel>lobar bronchus</classLabel>
<newAxiom>&apos;lobar bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;bronchus submucosal gland&apos;</newAxiom>
<newAxiom>&apos;lobar bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;bronchus smooth muscle&apos;</newAxiom>
<newAxiom>&apos;lobar bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;cartilage of bronchus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002184</classIRI>
<classLabel>segmental bronchus</classLabel>
<newAxiom>&apos;segmental bronchus&apos; SubClassOf &apos;overlaps&apos; some http://purl.obolibrary.org/obo/UBERON_8600017</newAxiom>
<newAxiom>&apos;segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;lung mesenchyme&apos;</newAxiom>
<newAxiom>&apos;segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;cartilage of bronchus&apos;</newAxiom>
<newAxiom>&apos;segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;bronchus smooth muscle&apos;</newAxiom>
<newAxiom>&apos;segmental bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;bronchus submucosal gland&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002186</classIRI>
<classLabel>bronchiole</classLabel>
<deletedAxiom>&apos;bronchiole&apos; SubClassOf &apos;part_of&apos; some &apos;pulmonary lobule&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002187</classIRI>
<classLabel>terminal bronchiole</classLabel>
<newAxiom>&apos;terminal bronchiole&apos; SubClassOf &apos;part_of&apos; some http://purl.obolibrary.org/obo/UBERON_0010369</newAxiom>
<newAxiom>&apos;terminal bronchiole&apos; SubClassOf &apos;distally connected to&apos; some &apos;pulmonary acinus&apos;</newAxiom>
<newAxiom>&apos;terminal bronchiole&apos; SubClassOf &apos;distally connected to&apos; some http://purl.obolibrary.org/obo/UBERON_0002188</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034517</classIRI>
<classLabel>ribophagy</classLabel>
<deletedAxiom>&apos;ribophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;ribosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;ribophagy&apos; SubClassOf &apos;has input&apos; some &apos;ribosome&apos;</deletedAxiom>
<deletedAxiom>&apos;ribophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;ribophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0006343</classIRI>
<classLabel>axillary shoot system</classLabel>
<newAxiom>&apos;axillary shoot system&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0012172</classIRI>
<classLabel>stomach primordium</classLabel>
<deletedAxiom>&apos;stomach primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0006204</classIRI>
<classLabel>sporocyte</classLabel>
<newAxiom>&apos;sporocyte&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0036069</classIRI>
<classLabel>tracheoesophageal fold</classLabel>
<deletedAxiom>&apos;tracheoesophageal fold&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048718</classIRI>
<classLabel>cibarial fish-trap bristle morphogenesis</classLabel>
<deletedAxiom>&apos;cibarial fish-trap bristle morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002540</classIRI>
<classLabel>lateral line system</classLabel>
<deletedAxiom>&apos;lateral line system&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097697</classIRI>
<classLabel>tRNA 5-carboxymethoxyuridine methyltransferase activity</classLabel>
<newAxiom>&apos;tRNA 5-carboxymethoxyuridine methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5-(carboxymethoxy)uridine 5&apos;-phosphate(2-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA 5-carboxymethoxyuridine methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5-methoxycarbonylmethoxyuridine(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA 5-carboxymethoxyuridine methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA 5-carboxymethoxyuridine methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009019</classIRI>
<classLabel>tRNA (guanine-N1-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine-N1-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009020</classIRI>
<classLabel>tRNA (guanosine-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2&apos;-O-methylguanosine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;guanosine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA 2&apos;-O-methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048612</classIRI>
<classLabel>post-embryonic ectodermal digestive tract development</classLabel>
<deletedAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf &apos;part_of&apos; some &apos;ectodermal digestive tract development&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf &apos;ectodermal digestive tract development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009048</classIRI>
<classLabel>dosage compensation by inactivation of X chromosome</classLabel>
<newAxiom>&apos;dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;in taxon&apos; only &apos;Amniota&apos;</newAxiom>
<newAxiom>&apos;dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;heterochromatin formation&apos;</newAxiom>
<newAxiom>&apos;dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Amniota&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097603</classIRI>
<classLabel>temperature-gated ion channel activity</classLabel>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034054</classIRI>
<classLabel>suppression by symbiont of host defense-related programmed cell death</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;negative regulation of programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048513</classIRI>
<classLabel>animal organ development</classLabel>
<deletedAxiom>&apos;animal organ development&apos; SubClassOf &apos;results in development of&apos; some &apos;organ&apos;</deletedAxiom>
<deletedAxiom>&apos;animal organ development&apos; EquivalentTo &apos;anatomical structure development&apos; and (&apos;results in development of&apos; some &apos;organ&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048563</classIRI>
<classLabel>post-embryonic animal organ morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf &apos;post-embryonic animal morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf &apos;part_of&apos; some &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048569</classIRI>
<classLabel>post-embryonic animal organ development</classLabel>
<deletedAxiom>&apos;post-embryonic animal organ development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048568</classIRI>
<classLabel>embryonic organ development</classLabel>
<newAxiom>&apos;embryonic organ development&apos; SubClassOf &apos;results in development of&apos; some &apos;organ&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097457</classIRI>
<classLabel>hippocampal mossy fiber</classLabel>
<deletedAxiom>&apos;hippocampal mossy fiber&apos; SubClassOf &apos;dentate gyrus mossy fiber&apos;</deletedAxiom>
<newAxiom>&apos;hippocampal mossy fiber&apos; SubClassOf &apos;axon&apos;</newAxiom>
<newAxiom>&apos;hippocampal mossy fiber&apos; SubClassOf &apos;part_of&apos; some &apos;hippocampal granule cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000425</classIRI>
<classLabel>pexophagy</classLabel>
<deletedAxiom>&apos;pexophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;pexophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;peroxisome&apos;)</deletedAxiom>
<newAxiom>&apos;pexophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000422</classIRI>
<classLabel>autophagy of mitochondrion</classLabel>
<deletedAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;mitochondrion disassembly&apos;</deletedAxiom>
<newAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;organelle disassembly&apos;</newAxiom>
<newAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;mitochondrion organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000423</classIRI>
<classLabel>mitophagy</classLabel>
<deletedAxiom>&apos;mitophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;mitochondrion&apos;)</deletedAxiom>
<deletedAxiom>&apos;mitophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;mitophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097247</classIRI>
<classLabel>epigallocatechin 3-gallate binding</classLabel>
<deletedAxiom>&apos;epigallocatechin 3-gallate binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000714</classIRI>
<classLabel>positive regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;positive regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;positively regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000712</classIRI>
<classLabel>regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000713</classIRI>
<classLabel>negative regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;negative regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;negatively regulates&apos; some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048185</classIRI>
<classLabel>activin binding</classLabel>
<newAxiom>&apos;activin binding&apos; SubClassOf &apos;has input&apos; some &apos;activin complex&apos;</newAxiom>
<newAxiom>&apos;activin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;activin complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000253</classIRI>
<classLabel>3-keto sterol reductase activity</classLabel>
<deletedAxiom>&apos;3-keto sterol reductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;4alpha-methyl-5alpha-cholest-7-en-3beta-ol&apos;</deletedAxiom>
<deletedAxiom>&apos;3-keto sterol reductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;4alpha-methyllathosterone&apos;</deletedAxiom>
<newAxiom>&apos;3-keto sterol reductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3beta-hydroxy steroid&apos;</newAxiom>
<newAxiom>&apos;3-keto sterol reductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3-oxo steroid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000166</classIRI>
<classLabel>nucleotide binding</classLabel>
<deletedAxiom>&apos;nucleotide binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048050</classIRI>
<classLabel>post-embryonic eye morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic eye morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000117</classIRI>
<classLabel>regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;part_of&apos; some &apos;G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097019</classIRI>
<classLabel>neurotransmitter receptor catabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor catabolic process&apos; SubClassOf &apos;receptor catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor catabolic process&apos; SubClassOf &apos;neurotransmitter receptor metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990247</classIRI>
<classLabel>N6-methyladenosine-containing RNA binding</classLabel>
<deletedAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf &apos;RNA binding&apos;</deletedAxiom>
<newAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf &apos;has_part&apos; some &apos;RNA binding&apos;</newAxiom>
<newAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf &apos;protein-RNA adaptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000083</classIRI>
<classLabel>regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;part_of&apos; some &apos;G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000820</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; SubClassOf &apos;part_of&apos; some &apos;smooth muscle cell differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;smooth muscle cell differentiation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0002002</classIRI>
<classLabel>embryo basal cell</classLabel>
<newAxiom>&apos;embryo basal cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990375</classIRI>
<classLabel>baculum development</classLabel>
<deletedAxiom>&apos;baculum development&apos; SubClassOf &apos;bone development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000763</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; SubClassOf &apos;part_of&apos; some &apos;norepinephrine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;norepinephrine biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004970</classIRI>
<classLabel>ionotropic glutamate receptor activity</classLabel>
<newAxiom>&apos;ionotropic glutamate receptor activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;glutamate(1-)&apos;)</newAxiom>
<newAxiom>&apos;ionotropic glutamate receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;glutamate(1-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905905</classIRI>
<classLabel>pharyngeal gland morphogenesis</classLabel>
<deletedAxiom>&apos;pharyngeal gland morphogenesis&apos; EquivalentTo &apos;anatomical structure morphogenesis&apos; and (&apos;results in morphogenesis of&apos; some &apos;pharyngeal gland&apos;)</deletedAxiom>
<deletedAxiom>&apos;pharyngeal gland morphogenesis&apos; SubClassOf &apos;gland morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;pharyngeal gland morphogenesis&apos; SubClassOf &apos;results in morphogenesis of&apos; some &apos;pharyngeal gland&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal gland morphogenesis&apos; SubClassOf &apos;anatomical structure morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905922</classIRI>
<classLabel>negative regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905923</classIRI>
<classLabel>positive regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905921</classIRI>
<classLabel>regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004808</classIRI>
<classLabel>tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038107</classIRI>
<classLabel>nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;nodal signaling pathway&apos; and (&apos;part_of&apos; some &apos;determination of left/right symmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;part_of&apos; some &apos;determination of left/right symmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004704</classIRI>
<classLabel>NF-kappaB-inducing kinase activity</classLabel>
<deletedAxiom>&apos;NF-kappaB-inducing kinase activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB-inducing kinase activity&apos; SubClassOf &apos;part_of&apos; some &apos;non-canonical NF-kappaB signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004741</classIRI>
<classLabel>[pyruvate dehydrogenase (lipoamide)] phosphatase activity</classLabel>
<deletedAxiom>&apos;[pyruvate dehydrogenase (lipoamide)] phosphatase activity&apos; SubClassOf &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;[pyruvate dehydrogenase (lipoamide)] phosphatase activity&apos; SubClassOf &apos;protein serine/threonine phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038056</classIRI>
<classLabel>negative regulation of BMP signaling pathway by negative regulation of BMP secretion</classLabel>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; SubClassOf &apos;negative regulation of BMP secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; SubClassOf &apos;negative regulation of BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;BMP signaling pathway&apos;) and (&apos;negatively regulates&apos; some &apos;BMP secretion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004557</classIRI>
<classLabel>alpha-galactosidase activity</classLabel>
<deletedAxiom>&apos;alpha-galactosidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-galactosidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;D-galactopyranose&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-galactosidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;D-glucopyranose&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-galactosidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;melibiose&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000073</classIRI>
<classLabel>regulation of cytokinesis, site selection</classLabel>
<deletedAxiom>&apos;regulation of cytokinesis, site selection&apos; SubClassOf &apos;regulation of localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006232</classIRI>
<classLabel>facio-acoustic VII-VIII preganglion complex</classLabel>
<deletedAxiom>&apos;facio-acoustic VII-VIII preganglion complex&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006236</classIRI>
<classLabel>tetrapod frontal bone primordium</classLabel>
<deletedAxiom>&apos;tetrapod frontal bone primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006268</classIRI>
<classLabel>notochordal process</classLabel>
<deletedAxiom>&apos;notochordal process&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006227</classIRI>
<classLabel>ethmoid bone primordium</classLabel>
<deletedAxiom>&apos;ethmoid bone primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006224</classIRI>
<classLabel>elbow joint primordium</classLabel>
<deletedAxiom>&apos;elbow joint primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006273</classIRI>
<classLabel>otic pit</classLabel>
<deletedAxiom>&apos;otic pit&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102772</classIRI>
<classLabel>sphingolipid long-chain base 4-hydroxylase activity</classLabel>
<deletedAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;iron(3+)&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;phytoceramide&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;dioxygen&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;iron(2+)&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;dihydroceramide&apos;</newAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901265</classIRI>
<classLabel>nucleoside phosphate binding</classLabel>
<deletedAxiom>&apos;nucleoside phosphate binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043827</classIRI>
<classLabel>tRNA (adenine-57, 58-N(1)-) methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine) methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(1)-methyladenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;adenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043855</classIRI>
<classLabel>cyclic nucleotide-gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;cyclic nucleotide-gated monoatomic ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;cyclic nucleotide-gated monoatomic ion channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;cyclic nucleotide binding&apos;</deletedAxiom>
<newAxiom>&apos;cyclic nucleotide-gated monoatomic ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;cyclic nucleotide&apos;</newAxiom>
<newAxiom>&apos;cyclic nucleotide-gated monoatomic ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;cyclic nucleotide&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018753</classIRI>
<classLabel>cyanuric acid amidohydrolase activity</classLabel>
<deletedAxiom>&apos;cyanuric acid amidohydrolase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;biuret&apos;</deletedAxiom>
<deletedAxiom>&apos;cyanuric acid amidohydrolase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;carbon dioxide&apos;</deletedAxiom>
<newAxiom>&apos;cyanuric acid amidohydrolase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;cyanuric acid amidohydrolase activity&apos; SubClassOf &apos;has_participant&apos; some http://purl.obolibrary.org/obo/CHEBI_142864</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901363</classIRI>
<classLabel>heterocyclic compound binding</classLabel>
<deletedAxiom>&apos;heterocyclic compound binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;heterocyclic compound&apos;)</deletedAxiom>
<deletedAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
<newAxiom>&apos;heterocyclic compound binding&apos; EquivalentTo &apos;small molecule binding&apos; and (&apos;has input&apos; some &apos;heterocyclic compound&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006757</classIRI>
<classLabel>lateral lingual swelling</classLabel>
<deletedAxiom>&apos;lateral lingual swelling&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006756</classIRI>
<classLabel>median lingual swelling</classLabel>
<deletedAxiom>&apos;median lingual swelling&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901522</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; SubClassOf &apos;part_of&apos; some &apos;cellular response to chemical stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;cellular response to chemical stimulus&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901585</classIRI>
<classLabel>regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of monoatomic ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901586</classIRI>
<classLabel>negative regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901587</classIRI>
<classLabel>positive regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043551</classIRI>
<classLabel>regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043552</classIRI>
<classLabel>positive regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043553</classIRI>
<classLabel>negative regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;negative regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043544</classIRI>
<classLabel>lipoamide binding</classLabel>
<deletedAxiom>&apos;lipoamide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043546</classIRI>
<classLabel>molybdopterin cofactor binding</classLabel>
<deletedAxiom>&apos;molybdopterin cofactor binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006598</classIRI>
<classLabel>presumptive structure</classLabel>
<deletedAxiom>&apos;presumptive structure&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_50906</classIRI>
<classLabel>role</classLabel>
<deletedAxiom>&apos;role&apos; SubClassOf &apos;realizable entity&apos;</deletedAxiom>
<deletedAxiom>&apos;role&apos; EquivalentTo &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0016611</classIRI>
<classLabel>auditory hillocks, pharyngeal arch 1 derived</classLabel>
<deletedAxiom>&apos;auditory hillocks, pharyngeal arch 1 derived&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0016612</classIRI>
<classLabel>auditory hillocks, pharyngeal arch 2 derived</classLabel>
<deletedAxiom>&apos;auditory hillocks, pharyngeal arch 2 derived&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002040</classIRI>
<classLabel>bronchial artery</classLabel>
<newAxiom>&apos;bronchial artery&apos; SubClassOf &apos;has_part&apos; some &apos;respiratory system arterial smooth muscle&apos;</newAxiom>
<newAxiom>&apos;bronchial artery&apos; SubClassOf &apos;has_part&apos; some &apos;respiratory system arterial endothelium&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002051</classIRI>
<classLabel>epithelium of bronchiole</classLabel>
<newAxiom>&apos;epithelium of bronchiole&apos; SubClassOf &apos;has_part&apos; some &apos;lung ciliated cell&apos;</newAxiom>
<newAxiom>&apos;epithelium of bronchiole&apos; SubClassOf &apos;has_part&apos; some &apos;club cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102189</classIRI>
<classLabel>4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043310</classIRI>
<classLabel>negative regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of eosinophil degranulation&apos; SubClassOf &apos;negative regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043311</classIRI>
<classLabel>positive regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of eosinophil degranulation&apos; SubClassOf &apos;positive regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043312</classIRI>
<classLabel>neutrophil degranulation</classLabel>
<deletedAxiom>&apos;neutrophil degranulation&apos; SubClassOf &apos;neutrophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;neutrophil degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;neutrophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043303</classIRI>
<classLabel>mast cell degranulation</classLabel>
<deletedAxiom>&apos;mast cell degranulation&apos; SubClassOf &apos;mast cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;mast cell degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;mast cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043304</classIRI>
<classLabel>regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of mast cell degranulation&apos; SubClassOf &apos;regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043305</classIRI>
<classLabel>negative regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of mast cell degranulation&apos; SubClassOf &apos;negative regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043306</classIRI>
<classLabel>positive regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of mast cell degranulation&apos; SubClassOf &apos;positive regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043308</classIRI>
<classLabel>eosinophil degranulation</classLabel>
<deletedAxiom>&apos;eosinophil degranulation&apos; SubClassOf &apos;eosinophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;eosinophil degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;eosinophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043309</classIRI>
<classLabel>regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of eosinophil degranulation&apos; SubClassOf &apos;regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033975</classIRI>
<classLabel>(R)-2-haloacid dehalogenase activity</classLabel>
<newAxiom>&apos;(R)-2-haloacid dehalogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;(R)-2-haloacid dehalogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;halide anion&apos;</newAxiom>
<newAxiom>&apos;(R)-2-haloacid dehalogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</newAxiom>
<newAxiom>&apos;(R)-2-haloacid dehalogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(R)-2-halocarboxylic acid anion&apos;</newAxiom>
<newAxiom>&apos;(R)-2-haloacid dehalogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(2S)-2-hydroxy monocarboxylic acid anion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043320</classIRI>
<classLabel>natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;natural killer cell degranulation&apos; SubClassOf &apos;natural killer cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;natural killer cell degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;natural killer cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043321</classIRI>
<classLabel>regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of natural killer cell degranulation&apos; SubClassOf &apos;regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043322</classIRI>
<classLabel>negative regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of natural killer cell degranulation&apos; SubClassOf &apos;negative regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043323</classIRI>
<classLabel>positive regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of natural killer cell degranulation&apos; SubClassOf &apos;positive regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043313</classIRI>
<classLabel>regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of neutrophil degranulation&apos; SubClassOf &apos;regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043314</classIRI>
<classLabel>negative regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of neutrophil degranulation&apos; SubClassOf &apos;negative regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043315</classIRI>
<classLabel>positive regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of neutrophil degranulation&apos; SubClassOf &apos;positive regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043316</classIRI>
<classLabel>cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;cytotoxic T cell degranulation&apos; SubClassOf &apos;T cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;cytotoxic T cell degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;T cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043317</classIRI>
<classLabel>regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043318</classIRI>
<classLabel>negative regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;negative regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043319</classIRI>
<classLabel>positive regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;positive regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043282</classIRI>
<classLabel>pharyngeal muscle development</classLabel>
<deletedAxiom>&apos;pharyngeal muscle development&apos; SubClassOf &apos;part_of&apos; some &apos;pharynx development&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal muscle development&apos; SubClassOf &apos;part_of&apos; some http://purl.obolibrary.org/obo/GO_0160093</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102040</classIRI>
<classLabel>fumarate reductase (menaquinone)</classLabel>
<deletedAxiom>&apos;fumarate reductase (menaquinone)&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;fumarate reductase (menaquinone)&apos; SubClassOf &apos;succinate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033771</classIRI>
<classLabel>licodione synthase activity</classLabel>
<deletedAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;licodione(1-)&apos;</deletedAxiom>
<deletedAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<deletedAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;liquiritigenin&apos;</deletedAxiom>
<newAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
<newAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;flavanones&apos;</newAxiom>
<newAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2-hydroxyflavanones&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043035</classIRI>
<classLabel>chromatin insulator sequence binding</classLabel>
<newAxiom>&apos;chromatin insulator sequence binding&apos; EquivalentTo &apos;chromatin DNA binding&apos; and (&apos;has input&apos; some &apos;insulator&apos;)</newAxiom>
<newAxiom>&apos;chromatin insulator sequence binding&apos; SubClassOf &apos;has input&apos; some &apos;insulator&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043050</classIRI>
<classLabel>pharyngeal pumping</classLabel>
<deletedAxiom>&apos;pharyngeal pumping&apos; SubClassOf &apos;occurs in&apos; some &apos;pharynx&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal pumping&apos; SubClassOf &apos;occurs in&apos; some http://purl.obolibrary.org/obo/UBERON_0015232</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0006965</classIRI>
<classLabel>vascular cord</classLabel>
<deletedAxiom>&apos;vascular cord&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008689</classIRI>
<classLabel>3-demethylubiquinone-9 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinone-9 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033668</classIRI>
<classLabel>suppression by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;negatively regulates&apos; some &apos;apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; SubClassOf &apos;negative regulation of apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; SubClassOf &apos;modulation by symbiont of host apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033657</classIRI>
<classLabel>disruption by symbiont of host chloroplast part</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host chloroplast part&apos; SubClassOf &apos;disruption by symbiont of host chloroplast&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033658</classIRI>
<classLabel>disruption by symbiont of host chloroplast thylakoid</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host chloroplast thylakoid&apos; SubClassOf &apos;disruption by symbiont of host chloroplast part&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host chloroplast thylakoid&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070525</classIRI>
<classLabel>tRNA threonylcarbamoyladenosine metabolic process</classLabel>
<deletedAxiom>&apos;tRNA threonylcarbamoyladenosine metabolic process&apos; SubClassOf &apos;RNA metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;tRNA threonylcarbamoyladenosine metabolic process&apos; SubClassOf &apos;tRNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001179</classIRI>
<classLabel>peritoneal cavity</classLabel>
<deletedAxiom>&apos;peritoneal cavity&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021510</classIRI>
<classLabel>spinal cord development</classLabel>
<deletedAxiom>&apos;spinal cord development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;spinal cord development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035973</classIRI>
<classLabel>aggrephagy</classLabel>
<deletedAxiom>&apos;aggrephagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;protein-containing complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;aggrephagy&apos; SubClassOf &apos;has input&apos; some &apos;protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;aggrephagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;aggrephagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060820</classIRI>
<classLabel>inactivation of X chromosome by heterochromatin formation</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by heterochromatin formation&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of X chromosome by heterochromatin formation&apos; SubClassOf &apos;constitutive heterochromatin formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035876</classIRI>
<classLabel>maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;part_of&apos; some &apos;meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045213</classIRI>
<classLabel>neurotransmitter receptor metabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor metabolic process&apos; SubClassOf &apos;receptor metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060819</classIRI>
<classLabel>inactivation of X chromosome by genomic imprinting</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;genomic imprinting&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060817</classIRI>
<classLabel>inactivation of paternal X chromosome</classLabel>
<deletedAxiom>&apos;inactivation of paternal X chromosome&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060818</classIRI>
<classLabel>inactivation of paternal X chromosome by genomic imprinting</classLabel>
<deletedAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;inactivation of paternal X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;inactivation of X chromosome by genomic imprinting&apos;</deletedAxiom>
<newAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</newAxiom>
<newAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;genomic imprinting&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060865</classIRI>
<classLabel>negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;regulation of floral organ abscission by signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;negative regulation of floral organ abscission&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; EquivalentTo &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos; and (&apos;negatively regulates&apos; some &apos;floral organ abscission&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060869</classIRI>
<classLabel>transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf &apos;part_of&apos; some &apos;floral organ abscission&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; EquivalentTo &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos; and (&apos;part_of&apos; some &apos;floral organ abscission&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045253</classIRI>
<classLabel>pyruvate dehydrogenase (lipoamide) phosphatase complex</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (lipoamide) phosphatase complex&apos; SubClassOf &apos;phosphatase complex&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate dehydrogenase (lipoamide) phosphatase complex&apos; SubClassOf &apos;protein serine/threonine phosphatase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070209</classIRI>
<classLabel>ASTRA complex</classLabel>
<deletedAxiom>&apos;ASTRA complex&apos; SubClassOf &apos;has_part&apos; some &apos;TTT complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070089</classIRI>
<classLabel>chloride-activated potassium channel activity</classLabel>
<deletedAxiom>&apos;chloride-activated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;potassium ion binding&apos;) and (&apos;has primary input&apos; some &apos;chloride&apos;)</deletedAxiom>
<deletedAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;potassium ion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;chloride channel activity&apos;</deletedAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chloride&apos;)</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;chloride&apos;</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060625</classIRI>
<classLabel>regulation of protein deneddylation</classLabel>
<deletedAxiom>&apos;regulation of protein deneddylation&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035658</classIRI>
<classLabel>Mon1-Ccz1 complex</classLabel>
<deletedAxiom>&apos;Mon1-Ccz1 complex&apos; DisjointWith &apos;in taxon&apos; some &apos;Schizosaccharomyces pombe&apos;</deletedAxiom>
<deletedAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Schizosaccharomyces pombe&apos;))</deletedAxiom>
<deletedAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Schizosaccharomyces pombe&apos;)</deletedAxiom>
<newAxiom>&apos;Mon1-Ccz1 complex&apos; DisjointWith &apos;in taxon&apos; some &apos;Schizosaccharomyces pombe&apos;</newAxiom>
<newAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Schizosaccharomyces pombe&apos;))</newAxiom>
<newAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Schizosaccharomyces pombe&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070040</classIRI>
<classLabel>rRNA (adenine-C2-)-methyltransferase activity</classLabel>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;adenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5&apos;-deoxyadenosine&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;di-mu-sulfido-diiron(1+)&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;di-mu-sulfido-diiron(2+)&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;rRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2-methyladenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035447</classIRI>
<classLabel>mycothiol synthase activity</classLabel>
<newAxiom>&apos;mycothiol synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;acetyl-CoA(4-)&apos;</newAxiom>
<newAxiom>&apos;mycothiol synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;1D-myo-inositol 2-(L-cysteiniumylamino)-2-deoxy-alpha-D-glucopyranoside&apos;</newAxiom>
<newAxiom>&apos;mycothiol synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;mycothiol&apos;</newAxiom>
<newAxiom>&apos;mycothiol synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;mycothiol synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;coenzyme A(4-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060408</classIRI>
<classLabel>regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060409</classIRI>
<classLabel>positive regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060410</classIRI>
<classLabel>negative regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050997</classIRI>
<classLabel>quaternary ammonium group binding</classLabel>
<deletedAxiom>&apos;quaternary ammonium group binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<deletedAxiom>&apos;quaternary ammonium group binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;quaternary nitrogen compound&apos;)</deletedAxiom>
<newAxiom>&apos;quaternary ammonium group binding&apos; EquivalentTo &apos;small molecule binding&apos; and (&apos;has input&apos; some &apos;quaternary nitrogen compound&apos;)</newAxiom>
<newAxiom>&apos;quaternary ammonium group binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098933</classIRI>
<classLabel>disruption by symbiont of host cell envelope</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;modification by symbiont of host cell wall&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035381</classIRI>
<classLabel>ATP-gated ion channel activity</classLabel>
<deletedAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;ATP binding&apos;</deletedAxiom>
<deletedAxiom>&apos;ATP-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;ATP binding&apos;) and (&apos;has primary input&apos; some &apos;ion&apos;)</deletedAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;ion&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;ATP(4-)&apos;)</newAxiom>
<newAxiom>&apos;ATP-gated ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;ATP(4-)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098864</classIRI>
<classLabel>stabilization of host tight cell-cell junction</classLabel>
<deletedAxiom>&apos;stabilization of host tight cell-cell junction&apos; SubClassOf &apos;disruption of host cell-cell junction&apos;</deletedAxiom>
<newAxiom>&apos;stabilization of host tight cell-cell junction&apos; SubClassOf &apos;disruption of host tight cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050825</classIRI>
<classLabel>ice binding</classLabel>
<deletedAxiom>&apos;ice binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;ice binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
<newAxiom>&apos;ice binding&apos; SubClassOf &apos;has input&apos; some &apos;water&apos;</newAxiom>
<newAxiom>&apos;ice binding&apos; EquivalentTo &apos;small molecule binding&apos; and (&apos;has input&apos; some &apos;water&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050809</classIRI>
<classLabel>diazepam binding</classLabel>
<deletedAxiom>&apos;diazepam binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098792</classIRI>
<classLabel>xenophagy</classLabel>
<deletedAxiom>&apos;xenophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;xenophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060190</classIRI>
<classLabel>negative regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;negative regulation of protein desumoylation&apos; SubClassOf &apos;negative regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060189</classIRI>
<classLabel>positive regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;positive regulation of protein desumoylation&apos; SubClassOf &apos;positive regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060188</classIRI>
<classLabel>regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;regulation of protein desumoylation&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001897</classIRI>
<classLabel>cytolysis by symbiont of host cells</classLabel>
<deletedAxiom>&apos;cytolysis by symbiont of host cells&apos; SubClassOf &apos;has_part&apos; some &apos;disruption by symbiont of host cell membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001956</classIRI>
<classLabel>cartilage of bronchus</classLabel>
<newAxiom>&apos;cartilage of bronchus&apos; SubClassOf &apos;has_part&apos; some &apos;tracheobronchial chondrocyte&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001958</classIRI>
<classLabel>terminal bronchiole epithelium</classLabel>
<newAxiom>&apos;terminal bronchiole epithelium&apos; SubClassOf &apos;has_part&apos; some &apos;lung ciliated cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001882</classIRI>
<classLabel>nucleoside binding</classLabel>
<deletedAxiom>&apos;nucleoside binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001968</classIRI>
<classLabel>semen</classLabel>
<deletedAxiom>&apos;semen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035126</classIRI>
<classLabel>post-embryonic genitalia morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic genitalia morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035166</classIRI>
<classLabel>post-embryonic hemopoiesis</classLabel>
<deletedAxiom>&apos;post-embryonic hemopoiesis&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098633</classIRI>
<classLabel>collagen fibril binding</classLabel>
<deletedAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<newAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001695</classIRI>
<classLabel>histamine catabolic process</classLabel>
<deletedAxiom>&apos;histamine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001707</classIRI>
<classLabel>nasal cavity</classLabel>
<deletedAxiom>&apos;nasal cavity&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001731</classIRI>
<classLabel>cavity of pharynx</classLabel>
<deletedAxiom>&apos;cavity of pharynx&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001504</classIRI>
<classLabel>neurotransmitter uptake</classLabel>
<deletedAxiom>&apos;neurotransmitter uptake&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001505</classIRI>
<classLabel>regulation of neurotransmitter levels</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; SubClassOf &apos;in taxon&apos; only &apos;Eumetazoa&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; SubClassOf &apos;regulates characteristic&apos; some &apos;neurotransmitter levels&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates characteristic&apos; some &apos;neurotransmitter levels&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0011757</classIRI>
<classLabel>differentiated genital tubercle</classLabel>
<deletedAxiom>&apos;differentiated genital tubercle&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050155</classIRI>
<classLabel>ornithine(lysine) transaminase activity</classLabel>
<deletedAxiom>&apos;ornithine(lysine) transaminase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905683</classIRI>
<classLabel>peroxisome disassembly</classLabel>
<deletedAxiom>&apos;peroxisome disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;peroxisome&apos;)</deletedAxiom>
<deletedAxiom>&apos;peroxisome disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;peroxisome&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisome disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisome disassembly&apos; SubClassOf &apos;peroxisome organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010905</classIRI>
<classLabel>clavicle bone primordium</classLabel>
<deletedAxiom>&apos;clavicle bone primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039722</classIRI>
<classLabel>suppression by virus of host toll-like receptor signaling pathway</classLabel>
<newAxiom>&apos;suppression by virus of host toll-like receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141105</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904408</classIRI>
<classLabel>melatonin binding</classLabel>
<deletedAxiom>&apos;melatonin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039699</classIRI>
<classLabel>viral mRNA cap methylation</classLabel>
<deletedAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
<newAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009955</classIRI>
<classLabel>neurogenic placode</classLabel>
<deletedAxiom>&apos;neurogenic placode&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009958</classIRI>
<classLabel>bladder lumen</classLabel>
<deletedAxiom>&apos;bladder lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039604</classIRI>
<classLabel>suppression by virus of host translation</classLabel>
<deletedAxiom>&apos;suppression by virus of host translation&apos; SubClassOf &apos;suppression by virus of host gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host translation&apos; SubClassOf &apos;induction by virus of catabolism of host mRNA&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039573</classIRI>
<classLabel>suppression by virus of host complement activation</classLabel>
<deletedAxiom>&apos;suppression by virus of host complement activation&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009844</classIRI>
<classLabel>urogenital sinus lumen</classLabel>
<deletedAxiom>&apos;urogenital sinus lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0034878</classIRI>
<classLabel>prechordal mesoderm</classLabel>
<deletedAxiom>&apos;prechordal mesoderm&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039503</classIRI>
<classLabel>suppression by virus of host innate immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039504</classIRI>
<classLabel>suppression by virus of host adaptive immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;negatively regulates&apos; some &apos;adaptive immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (&apos;negatively regulates&apos; some &apos;adaptive immune response&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;perturbation by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039505</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;negative regulation of adaptive immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039502</classIRI>
<classLabel>suppression by virus of host type I interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of type I interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;type I interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039532</classIRI>
<classLabel>negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway&apos; SubClassOf &apos;negative regulation of defense response to virus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039526</classIRI>
<classLabel>modulation by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;modulation by virus of host apoptotic process&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (&apos;regulates&apos; some &apos;apoptotic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009714</classIRI>
<classLabel>intermaxillary process</classLabel>
<deletedAxiom>&apos;intermaxillary process&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009670</classIRI>
<classLabel>rectal lumen</classLabel>
<deletedAxiom>&apos;rectal lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009676</classIRI>
<classLabel>early telencephalic vesicle</classLabel>
<deletedAxiom>&apos;early telencephalic vesicle&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015269</classIRI>
<classLabel>calcium-activated potassium channel activity</classLabel>
<deletedAxiom>&apos;calcium-activated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;positively regulated by&apos; some &apos;calcium ion binding&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;calcium-activated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;calcium(2+)&apos;)</newAxiom>
<newAxiom>&apos;calcium-activated potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;calcium(2+)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015277</classIRI>
<classLabel>kainate selective glutamate receptor activity</classLabel>
<deletedAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;sodium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;glutamate(1-)&apos;)</newAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;ligand-gated sodium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015278</classIRI>
<classLabel>calcium-release channel activity</classLabel>
<deletedAxiom>&apos;calcium-release channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;part_of&apos; some &apos;release of sequestered calcium ion into cytosol&apos;) and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;calcium-release channel activity&apos; SubClassOf &apos;part_of&apos; some &apos;release of sequestered calcium ion into cytosol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
<newAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015280</classIRI>
<classLabel>ligand-gated sodium channel activity</classLabel>
<newAxiom>&apos;ligand-gated sodium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;sodium(1+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005095</classIRI>
<classLabel>kidney rudiment</classLabel>
<deletedAxiom>&apos;kidney rudiment&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030696</classIRI>
<classLabel>tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030697</classIRI>
<classLabel>S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (m5U54) methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030698</classIRI>
<classLabel>5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (m5U54) methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;5,10-methylenetetrahydrofolate-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_51086</classIRI>
<classLabel>chemical role</classLabel>
<deletedAxiom>&apos;chemical role&apos; SubClassOf &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0040025</classIRI>
<classLabel>vulval development</classLabel>
<deletedAxiom>&apos;vulval development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;vulval development&apos; SubClassOf &apos;animal organ development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030509</classIRI>
<classLabel>BMP signaling pathway</classLabel>
<deletedAxiom>&apos;BMP signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;BMP signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030594</classIRI>
<classLabel>neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf &apos;has_part&apos; some &apos;neurotransmitter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005564</classIRI>
<classLabel>gonad primordium</classLabel>
<deletedAxiom>&apos;gonad primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005527</classIRI>
<classLabel>macrolide binding</classLabel>
<deletedAxiom>&apos;macrolide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900095</classIRI>
<classLabel>regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Aves&apos;))</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Aves&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; DisjointWith &apos;in taxon&apos; some &apos;Aves&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900096</classIRI>
<classLabel>negative regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;negative regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;negatively regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900097</classIRI>
<classLabel>positive regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;positive regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;positively regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005597</classIRI>
<classLabel>lung primordium</classLabel>
<deletedAxiom>&apos;lung primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005422</classIRI>
<classLabel>pelvic appendage apical ectodermal ridge</classLabel>
<deletedAxiom>&apos;pelvic appendage apical ectodermal ridge&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005421</classIRI>
<classLabel>pectoral appendage apical ectodermal ridge</classLabel>
<deletedAxiom>&apos;pectoral appendage apical ectodermal ridge&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900224</classIRI>
<classLabel>positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of activin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positively regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900164</classIRI>
<classLabel>nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;nodal signaling pathway&apos; and (&apos;part_of&apos; some &apos;determination of left/right asymmetry in lateral mesoderm&apos;)</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;part_of&apos; some &apos;determination of left/right asymmetry in lateral mesoderm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900175</classIRI>
<classLabel>regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900176</classIRI>
<classLabel>negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;negatively regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900145</classIRI>
<classLabel>regulation of nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulates&apos; some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900146</classIRI>
<classLabel>negative regulation of nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of developmental process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negatively regulates&apos; some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030398</classIRI>
<classLabel>peroxisomal membrane disassembly</classLabel>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;peroxisomal membrane&apos;)</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;peroxisomal membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;membrane disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;part_of&apos; some &apos;autophagy of peroxisome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005311</classIRI>
<classLabel>mammary placode</classLabel>
<deletedAxiom>&apos;mammary placode&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005381</classIRI>
<classLabel>dentate gyrus granule cell layer</classLabel>
<deletedAxiom>&apos;dentate gyrus granule cell layer&apos; SubClassOf &apos;composed primarily of&apos; some &apos;granule cell&apos;</deletedAxiom>
<newAxiom>&apos;dentate gyrus granule cell layer&apos; SubClassOf &apos;composed primarily of&apos; some &apos;dentate gyrus granule cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019865</classIRI>
<classLabel>immunoglobulin binding</classLabel>
<newAxiom>&apos;immunoglobulin binding&apos; SubClassOf &apos;has input&apos; some &apos;immunoglobulin complex&apos;</newAxiom>
<newAxiom>&apos;immunoglobulin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;immunoglobulin complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005227</classIRI>
<classLabel>calcium activated cation channel activity</classLabel>
<deletedAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;monoatomic cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;calcium activated cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;positively regulated by&apos; some &apos;calcium ion binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;positively regulated by&apos; some &apos;calcium ion binding&apos;</deletedAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;calcium ion&apos;)</newAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;calcium ion&apos;</newAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005228</classIRI>
<classLabel>intracellular sodium activated potassium channel activity</classLabel>
<newAxiom>&apos;intracellular sodium activated potassium channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005343</classIRI>
<classLabel>cortical plate</classLabel>
<deletedAxiom>&apos;cortical plate&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044804</classIRI>
<classLabel>nucleophagy</classLabel>
<deletedAxiom>&apos;nucleophagy&apos; SubClassOf &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;nucleophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044805</classIRI>
<classLabel>late nucleophagy</classLabel>
<deletedAxiom>&apos;late nucleophagy&apos; SubClassOf &apos;nucleophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005244</classIRI>
<classLabel>voltage-gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;voltage-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044832</classIRI>
<classLabel>induction by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030242</classIRI>
<classLabel>autophagy of peroxisome</classLabel>
<deletedAxiom>&apos;autophagy of peroxisome&apos; SubClassOf &apos;has_part&apos; some &apos;peroxisome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019811</classIRI>
<classLabel>cocaine binding</classLabel>
<deletedAxiom>&apos;cocaine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019726</classIRI>
<classLabel>mevaldate reductase (NADPH) activity</classLabel>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NADPH(4-)&apos;</deletedAxiom>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</deletedAxiom>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;mevaldate&apos;</deletedAxiom>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;(R)-mevalonate&apos;</deletedAxiom>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;mevaldate reductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NADP(3-)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005294</classIRI>
<classLabel>gonadal ridge</classLabel>
<deletedAxiom>&apos;gonadal ridge&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044736</classIRI>
<classLabel>acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;acid-sensing ion channel activity&apos; SubClassOf &apos;ligand-gated sodium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;acid-sensing ion channel activity&apos; SubClassOf &apos;ligand-gated monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005158</classIRI>
<classLabel>insulin receptor binding</classLabel>
<deletedAxiom>&apos;insulin receptor binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005178</classIRI>
<classLabel>integrin binding</classLabel>
<newAxiom>&apos;integrin binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;integrin complex&apos;)</newAxiom>
<newAxiom>&apos;integrin binding&apos; SubClassOf &apos;has input&apos; some &apos;integrin complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044689</classIRI>
<classLabel>7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity</classLabel>
<deletedAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5&apos;-deoxyadenosine&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some http://purl.obolibrary.org/obo/CHEBI_85936</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;ammonium&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin(1-)&apos;</newAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;ammonia-lyase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005971</classIRI>
<classLabel>amniotic fold</classLabel>
<deletedAxiom>&apos;amniotic fold&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0008030</classIRI>
<classLabel>trichome cell</classLabel>
<newAxiom>&apos;trichome cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044660</classIRI>
<classLabel>viral release via pore formation in host cell membrane</classLabel>
<deletedAxiom>&apos;viral release via pore formation in host cell membrane&apos; SubClassOf &apos;has_part&apos; some &apos;disruption of plasma membrane integrity in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044658</classIRI>
<classLabel>pore formation in host plasma membrane</classLabel>
<newAxiom>&apos;pore formation in host plasma membrane&apos; SubClassOf &apos;disruption of plasma membrane integrity in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044673</classIRI>
<classLabel>7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex</classLabel>
<deletedAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex&apos; SubClassOf &apos;transferase complex&apos;</deletedAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex&apos; SubClassOf &apos;catalytic complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044596</classIRI>
<classLabel>3-demethylubiquinol-10 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinol-10 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005868</classIRI>
<classLabel>maxillary prominence</classLabel>
<deletedAxiom>&apos;maxillary prominence&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005867</classIRI>
<classLabel>mandibular prominence</classLabel>
<deletedAxiom>&apos;mandibular prominence&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005870</classIRI>
<classLabel>olfactory pit</classLabel>
<deletedAxiom>&apos;olfactory pit&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005876</classIRI>
<classLabel>undifferentiated genital tubercle</classLabel>
<deletedAxiom>&apos;undifferentiated genital tubercle&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FAO_0000048</classIRI>
<classLabel>Hulle cell</classLabel>
<deletedAxiom>&apos;Hulle cell&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;Hulle cell&apos; SubClassOf &apos;independent continuant&apos;</newAxiom>
<newAxiom>&apos;Hulle cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/FAO_0000043</classIRI>
<classLabel>conidiophore</classLabel>
<deletedAxiom>&apos;conidiophore&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;conidiophore&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
<newAxiom>&apos;conidiophore&apos; SubClassOf &apos;independent continuant&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044414</classIRI>
<classLabel>suppression of host defenses by symbiont</classLabel>
<deletedAxiom>&apos;suppression of host defenses by symbiont&apos; SubClassOf &apos;negative regulation of defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of host defenses by symbiont&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044405</classIRI>
<classLabel>detection of host</classLabel>
<deletedAxiom>&apos;detection of host&apos; SubClassOf &apos;detection of other organism&apos;</deletedAxiom>
<deletedAxiom>&apos;detection of host&apos; SubClassOf &apos;response to host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005629</classIRI>
<classLabel>vascular plexus</classLabel>
<deletedAxiom>&apos;vascular plexus&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005625</classIRI>
<classLabel>tubotympanic recess lumen</classLabel>
<deletedAxiom>&apos;tubotympanic recess lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044302</classIRI>
<classLabel>dentate gyrus mossy fiber</classLabel>
<deletedAxiom>&apos;dentate gyrus mossy fiber&apos; SubClassOf &apos;axon&apos;</deletedAxiom>
<newAxiom>&apos;dentate gyrus mossy fiber&apos; SubClassOf &apos;hippocampal mossy fiber&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022839</classIRI>
<classLabel>monoatomic ion gated channel activity</classLabel>
<deletedAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monoatomic ion gated channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;monoatomic ion gated channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;monoatomic ion&apos;)</newAxiom>
<newAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;monoatomic ion&apos;</newAxiom>
<newAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;ligand-gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022834</classIRI>
<classLabel>ligand-gated channel activity</classLabel>
<newAxiom>&apos;ligand-gated channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
<newAxiom>&apos;ligand-gated channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022835</classIRI>
<classLabel>transmitter-gated channel activity</classLabel>
<deletedAxiom>&apos;transmitter-gated channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;neurotransmitter binding&apos;</deletedAxiom>
<deletedAxiom>&apos;transmitter-gated channel activity&apos; EquivalentTo &apos;channel activity&apos; and (&apos;regulated by&apos; some &apos;neurotransmitter binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022852</classIRI>
<classLabel>glycine-gated chloride ion channel activity</classLabel>
<deletedAxiom>&apos;glycine-gated chloride ion channel activity&apos; SubClassOf &apos;has input&apos; some &apos;glycine zwitterion&apos;</deletedAxiom>
<newAxiom>&apos;glycine-gated chloride ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;glycine zwitterion&apos;)</newAxiom>
<newAxiom>&apos;glycine-gated chloride ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;glycine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022851</classIRI>
<classLabel>GABA-gated chloride ion channel activity</classLabel>
<deletedAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf &apos;GABA receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;GABA-gated chloride ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;gamma-aminobutyric acid zwitterion&apos;)</newAxiom>
<newAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;gamma-aminobutyric acid zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022850</classIRI>
<classLabel>serotonin-gated monoatomic cation-selective channel activity</classLabel>
<deletedAxiom>&apos;serotonin-gated monoatomic cation-selective channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;serotonin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;serotonin-gated monoatomic cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;serotonin binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<newAxiom>&apos;serotonin-gated monoatomic cation-selective channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;serotonin(1+)&apos;)</newAxiom>
<newAxiom>&apos;serotonin-gated monoatomic cation-selective channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;serotonin(1+)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022849</classIRI>
<classLabel>glutamate-gated calcium ion channel activity</classLabel>
<newAxiom>&apos;glutamate-gated calcium ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;glutamate(1-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022848</classIRI>
<classLabel>acetylcholine-gated monoatomic cation-selective channel activity</classLabel>
<deletedAxiom>&apos;acetylcholine-gated monoatomic cation-selective channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;acetylcholine binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine-gated monoatomic cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;acetylcholine binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<newAxiom>&apos;acetylcholine-gated monoatomic cation-selective channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;acetylcholine&apos;</newAxiom>
<newAxiom>&apos;acetylcholine-gated monoatomic cation-selective channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;acetylcholine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007250</classIRI>
<classLabel>activation of NF-kappaB-inducing kinase activity</classLabel>
<deletedAxiom>&apos;activation of NF-kappaB-inducing kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;NF-kappaB-inducing kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;activation of NF-kappaB-inducing kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;NF-kappaB-inducing kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007269</classIRI>
<classLabel>neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;neurotransmitter secretion&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007179</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;transforming growth factor beta receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046775</classIRI>
<classLabel>suppression by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046774</classIRI>
<classLabel>suppression by virus of host intracellular interferon activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host intracellular interferon activity&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007105</classIRI>
<classLabel>cytokinesis, division site positioning</classLabel>
<deletedAxiom>&apos;cytokinesis, division site positioning&apos; SubClassOf &apos;contractile ring localization&apos;</deletedAxiom>
<newAxiom>&apos;cytokinesis, division site positioning&apos; SubClassOf &apos;cytokinetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004875</classIRI>
<classLabel>nephrogenic cord</classLabel>
<deletedAxiom>&apos;nephrogenic cord&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007073</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007072</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;exit from mitosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf &apos;part_of&apos; some &apos;exit from mitosis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007075</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007074</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004884</classIRI>
<classLabel>lobar bronchus mesenchyme</classLabel>
<newAxiom>&apos;lobar bronchus mesenchyme&apos; SubClassOf &apos;has_part&apos; some &apos;tracheobronchial smooth muscle cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004750</classIRI>
<classLabel>blastoderm</classLabel>
<deletedAxiom>&apos;blastoderm&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014903</classIRI>
<classLabel>primordial vasculature</classLabel>
<deletedAxiom>&apos;primordial vasculature&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061912</classIRI>
<classLabel>selective autophagy</classLabel>
<deletedAxiom>&apos;selective autophagy&apos; SubClassOf &apos;macroautophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061903</classIRI>
<classLabel>positive regulation of 1-phosphatidylinositol-3-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000164</classIRI>
<classLabel>primitive urogenital sinus</classLabel>
<deletedAxiom>&apos;primitive urogenital sinus&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000111</classIRI>
<classLabel>organogenesis stage</classLabel>
<deletedAxiom>&apos;organogenesis stage&apos; SubClassOf &apos;preceded by&apos; some &apos;neurula stage&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046333</classIRI>
<classLabel>octopamine metabolic process</classLabel>
<deletedAxiom>&apos;octopamine metabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046334</classIRI>
<classLabel>octopamine catabolic process</classLabel>
<deletedAxiom>&apos;octopamine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000178</classIRI>
<classLabel>blood</classLabel>
<deletedAxiom>&apos;blood&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000038</classIRI>
<classLabel>follicular fluid</classLabel>
<deletedAxiom>&apos;follicular fluid&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061816</classIRI>
<classLabel>proteaphagy</classLabel>
<deletedAxiom>&apos;proteaphagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;proteasome complex&apos;)</deletedAxiom>
<deletedAxiom>&apos;proteaphagy&apos; SubClassOf &apos;aggrephagy&apos;</deletedAxiom>
<deletedAxiom>&apos;proteaphagy&apos; SubClassOf &apos;has input&apos; some &apos;proteasome complex&apos;</deletedAxiom>
<newAxiom>&apos;proteaphagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000091</classIRI>
<classLabel>bilaminar disc</classLabel>
<deletedAxiom>&apos;bilaminar disc&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000088</classIRI>
<classLabel>trophoblast</classLabel>
<deletedAxiom>&apos;trophoblast&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000087</classIRI>
<classLabel>inner cell mass</classLabel>
<deletedAxiom>&apos;inner cell mass&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_33232</classIRI>
<classLabel>application</classLabel>
<deletedAxiom>&apos;application&apos; SubClassOf &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0014704</classIRI>
<classLabel>pleuroperitoneal canal lumen</classLabel>
<deletedAxiom>&apos;pleuroperitoneal canal lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061723</classIRI>
<classLabel>glycophagy</classLabel>
<deletedAxiom>&apos;glycophagy&apos; SubClassOf &apos;glycogen catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glycophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;glycophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has primary input&apos; some &apos;glycogen&apos;)</deletedAxiom>
<newAxiom>&apos;glycophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061726</classIRI>
<classLabel>mitochondrion disassembly</classLabel>
<deletedAxiom>&apos;mitochondrion disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion disassembly&apos; SubClassOf &apos;mitochondrion organization&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion disassembly&apos; SubClassOf &apos;results in disassembly of&apos; some &apos;mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion disassembly&apos; EquivalentTo &apos;cellular component disassembly&apos; and (&apos;results in disassembly of&apos; some &apos;mitochondrion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061724</classIRI>
<classLabel>lipophagy</classLabel>
<deletedAxiom>&apos;lipophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;lipophagy&apos; SubClassOf &apos;has input&apos; some &apos;lipid droplet&apos;</deletedAxiom>
<deletedAxiom>&apos;lipophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;lipid droplet&apos;)</deletedAxiom>
<newAxiom>&apos;lipophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061709</classIRI>
<classLabel>reticulophagy</classLabel>
<deletedAxiom>&apos;reticulophagy&apos; SubClassOf &apos;has input&apos; some &apos;endoplasmic reticulum&apos;</deletedAxiom>
<deletedAxiom>&apos;reticulophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;endoplasmic reticulum&apos;)</deletedAxiom>
<deletedAxiom>&apos;reticulophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;reticulophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061738</classIRI>
<classLabel>late endosomal microautophagy</classLabel>
<deletedAxiom>&apos;late endosomal microautophagy&apos; SubClassOf &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;late endosomal microautophagy&apos; SubClassOf &apos;lysosomal microautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061797</classIRI>
<classLabel>pH-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009122</classIRI>
<classLabel>adenohypophyseal placode</classLabel>
<deletedAxiom>&apos;adenohypophyseal placode&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036524</classIRI>
<classLabel>protein deglycase activity</classLabel>
<deletedAxiom>&apos;protein deglycase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein deglycase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061542</classIRI>
<classLabel>3-demethylubiquinol-n 3-O-methyltransferase activity</classLabel>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3-demethylubiquinol&apos;</newAxiom>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;ubiquinol&apos;</newAxiom>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061419</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to hypoxia</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002935</classIRI>
<classLabel>tRNA (adenine-C2-)-methyltransferase activity</classLabel>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2-methyladenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;adenosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5&apos;-deoxyadenosine&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;di-mu-sulfido-diiron(1+)&apos;</newAxiom>
<newAxiom>&apos;tRNA (adenine-C2-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;di-mu-sulfido-diiron(2+)&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000358</classIRI>
<classLabel>blastocyst</classLabel>
<deletedAxiom>&apos;blastocyst&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160039</classIRI>
<classLabel>serotonin-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;serotonin-gated chloride channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;serotonin binding&apos;) and (&apos;has primary input&apos; some &apos;chloride&apos;)</deletedAxiom>
<deletedAxiom>&apos;serotonin-gated chloride channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;serotonin binding&apos;</deletedAxiom>
<newAxiom>&apos;serotonin-gated chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;serotonin(1+)&apos;</newAxiom>
<newAxiom>&apos;serotonin-gated chloride channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;chloride&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;serotonin(1+)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160079</classIRI>
<classLabel>metabotropic glycine receptor activity</classLabel>
<deletedAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;G protein-coupled neurotransmitter receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904081</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; SubClassOf &apos;part_of&apos; some &apos;neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0004535</classIRI>
<classLabel>fruit placenta</classLabel>
<newAxiom>&apos;fruit placenta&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036214</classIRI>
<classLabel>contractile ring localization</classLabel>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;localization&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;has primary input&apos; some &apos;contractile ring&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;part_of&apos; some &apos;cytoskeleton-dependent cytokinesis&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; EquivalentTo &apos;localization&apos; and (&apos;has primary input&apos; some &apos;contractile ring&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010531</classIRI>
<classLabel>metanephros induced blastemal cells</classLabel>
<deletedAxiom>&apos;metanephros induced blastemal cells&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009576</classIRI>
<classLabel>medulla oblongata sulcus limitans</classLabel>
<deletedAxiom>&apos;medulla oblongata sulcus limitans&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009572</classIRI>
<classLabel>lumen of central canal of spinal cord</classLabel>
<deletedAxiom>&apos;lumen of central canal of spinal cord&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051760</classIRI>
<classLabel>meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;meiotic sister chromatid cohesion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051740</classIRI>
<classLabel>ethylene binding</classLabel>
<deletedAxiom>&apos;ethylene binding&apos; SubClassOf &apos;alkene binding&apos;</deletedAxiom>
<newAxiom>&apos;ethylene binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036091</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099604</classIRI>
<classLabel>ligand-gated calcium channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated calcium channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated calcium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;calcium(2+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0000931</classIRI>
<classLabel>proctodeum</classLabel>
<deletedAxiom>&apos;proctodeum&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075528</classIRI>
<classLabel>perturbation by virus of host immune response</classLabel>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (&apos;regulates&apos; some &apos;immune response&apos;)</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf &apos;regulates&apos; some &apos;immune response&apos;</deletedAxiom>
<newAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051580</classIRI>
<classLabel>regulation of neurotransmitter uptake</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter uptake&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010368</classIRI>
<classLabel>pulmonary lobule</classLabel>
<deletedAxiom>&apos;pulmonary lobule&apos; SubClassOf &apos;protein-containing material entity&apos;</deletedAxiom>
<deletedAxiom>&apos;pulmonary lobule&apos; SubClassOf &apos;has_part&apos; some &apos;terminal bronchiole&apos;</deletedAxiom>
<newAxiom>&apos;pulmonary lobule&apos; SubClassOf &apos;part_of&apos; some http://purl.obolibrary.org/obo/UBERON_8600017</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010312</classIRI>
<classLabel>immature eye</classLabel>
<deletedAxiom>&apos;immature eye&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009142</classIRI>
<classLabel>entire embryonic mesenchyme</classLabel>
<deletedAxiom>&apos;entire embryonic mesenchyme&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002561</classIRI>
<classLabel>basophil degranulation</classLabel>
<deletedAxiom>&apos;basophil degranulation&apos; SubClassOf &apos;basophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;basophil degranulation&apos; SubClassOf &apos;part_of&apos; some &apos;basophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010210</classIRI>
<classLabel>blood clot</classLabel>
<deletedAxiom>&apos;blood clot&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0009210</classIRI>
<classLabel>pharyngeal membrane</classLabel>
<deletedAxiom>&apos;pharyngeal membrane&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051378</classIRI>
<classLabel>serotonin binding</classLabel>
<deletedAxiom>&apos;serotonin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051381</classIRI>
<classLabel>histamine binding</classLabel>
<deletedAxiom>&apos;histamine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110129</classIRI>
<classLabel>SHREC2 complex</classLabel>
<deletedAxiom>&apos;SHREC2 complex&apos; SubClassOf &apos;has_part&apos; some &apos;SHREC complex&apos;</deletedAxiom>
<deletedAxiom>&apos;SHREC2 complex&apos; SubClassOf &apos;NuRD complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002281</classIRI>
<classLabel>macrophage activation involved in immune response</classLabel>
<deletedAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf &apos;myeloid cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf &apos;part_of&apos; some &apos;myeloid cell activation involved in immune response&apos;</newAxiom>
<newAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf &apos;leukocyte activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002276</classIRI>
<classLabel>basophil activation involved in immune response</classLabel>
<deletedAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf &apos;myeloid cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf &apos;part_of&apos; some &apos;myeloid cell activation involved in immune response&apos;</newAxiom>
<newAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf &apos;leukocyte activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110041</classIRI>
<classLabel>regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of pharynx morphogenesis&apos; SubClassOf &apos;regulation of anatomical structure morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pharynx morphogenesis&apos; SubClassOf &apos;regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110040</classIRI>
<classLabel>pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;anatomical structure morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;results in morphogenesis of&apos; some &apos;pharynx&apos;</deletedAxiom>
<deletedAxiom>&apos;pharynx morphogenesis&apos; EquivalentTo &apos;anatomical structure morphogenesis&apos; and (&apos;results in morphogenesis of&apos; some &apos;pharynx&apos;)</deletedAxiom>
<newAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</newAxiom>
<newAxiom>&apos;pharynx morphogenesis&apos; EquivalentTo &apos;anatomical structure morphogenesis&apos; and (&apos;results in morphogenesis of&apos; some http://purl.obolibrary.org/obo/UBERON_0015232)</newAxiom>
<newAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;results in morphogenesis of&apos; some http://purl.obolibrary.org/obo/UBERON_0015232</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110043</classIRI>
<classLabel>positive regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;positive regulation of pharynx morphogenesis&apos; SubClassOf &apos;positive regulation of developmental process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of pharynx morphogenesis&apos; SubClassOf &apos;positive regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110042</classIRI>
<classLabel>negative regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of pharynx morphogenesis&apos; SubClassOf &apos;negative regulation of developmental process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of pharynx morphogenesis&apos; SubClassOf &apos;negative regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0089715</classIRI>
<classLabel>tRNA m6t6A37 methyltransferase activity</classLabel>
<newAxiom>&apos;tRNA m6t6A37 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(6)-L-threonylcarbamoyladenine 5&apos;-monophosphate(2-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA m6t6A37 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some http://purl.obolibrary.org/obo/CHEBI_188470</newAxiom>
<newAxiom>&apos;tRNA m6t6A37 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;tRNA m6t6A37 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA m6t6A37 methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903341</classIRI>
<classLabel>regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903343</classIRI>
<classLabel>positive regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903342</classIRI>
<classLabel>negative regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099100</classIRI>
<classLabel>G-protein gated monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;monoatomic cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;G-protein gated monoatomic ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099101</classIRI>
<classLabel>G-protein gated potassium channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;)</deletedAxiom>
<deletedAxiom>&apos;G-protein gated potassium channel activity&apos; SubClassOf &apos;G-protein gated monoatomic cation channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075118</classIRI>
<classLabel>perturbation of host G protein-coupled receptor signal transduction pathway</classLabel>
<newAxiom>&apos;perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf &apos;symbiont-mediated activation of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009010</classIRI>
<classLabel>seed</classLabel>
<newAxiom>&apos;seed&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099094</classIRI>
<classLabel>ligand-gated monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated monoatomic cation channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated monoatomic cation channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099095</classIRI>
<classLabel>ligand-gated monoatomic anion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated monoatomic anion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;)</deletedAxiom>
<newAxiom>&apos;ligand-gated monoatomic anion channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic anion&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;chemical entity&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090686</classIRI>
<classLabel>glycine betaine-activated nonselective monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;glycine betaine-activated nonselective monoatomic cation channel activity&apos; SubClassOf &apos;amino-acid betaine transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine betaine-activated nonselective monoatomic cation channel activity&apos; EquivalentTo &apos;ligand-gated monoatomic ion channel activity&apos; and (&apos;has primary input&apos; some &apos;glycine betaine&apos;) and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;)</deletedAxiom>
<newAxiom>&apos;glycine betaine-activated nonselective monoatomic cation channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0012001 some &apos;glycine betaine&apos;</newAxiom>
<newAxiom>&apos;glycine betaine-activated nonselective monoatomic cation channel activity&apos; EquivalentTo &apos;ligand-gated monoatomic ion channel activity&apos; and (&apos;has primary input&apos; some &apos;monoatomic cation&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;glycine betaine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009049</classIRI>
<classLabel>inflorescence</classLabel>
<deletedAxiom>&apos;inflorescence&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;inflorescence&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;) and (&apos;has primary input&apos; some &apos;monoatomic ion&apos;)</deletedAxiom>
<deletedAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;regulated by&apos; some &apos;G-protein beta/gamma-subunit complex binding&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009046</classIRI>
<classLabel>flower</classLabel>
<newAxiom>&apos;flower&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009005</classIRI>
<classLabel>root</classLabel>
<newAxiom>&apos;root&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009001</classIRI>
<classLabel>fruit</classLabel>
<newAxiom>&apos;fruit&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016719</classIRI>
<classLabel>carotene 7,8-desaturase activity</classLabel>
<deletedAxiom>&apos;carotene 7,8-desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<newAxiom>&apos;carotene 7,8-desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002054</classIRI>
<classLabel>nucleobase binding</classLabel>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009062</classIRI>
<classLabel>gynoecium</classLabel>
<newAxiom>&apos;gynoecium&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009061</classIRI>
<classLabel>androecium</classLabel>
<newAxiom>&apos;androecium&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0009066</classIRI>
<classLabel>anther</classLabel>
<newAxiom>&apos;anther&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051039</classIRI>
<classLabel>positive regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051038</classIRI>
<classLabel>negative regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051037</classIRI>
<classLabel>regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;part_of&apos; some &apos;meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000115</classIRI>
<classLabel>socket cell</classLabel>
<newAxiom>&apos;socket cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016580</classIRI>
<classLabel>Sin3 complex</classLabel>
<deletedAxiom>&apos;Sin3 complex&apos; SubClassOf &apos;Sin3-type complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903595</classIRI>
<classLabel>positive regulation of histamine secretion by mast cell</classLabel>
<newAxiom>&apos;positive regulation of histamine secretion by mast cell&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016596</classIRI>
<classLabel>thienylcyclohexylpiperidine binding</classLabel>
<deletedAxiom>&apos;thienylcyclohexylpiperidine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903581</classIRI>
<classLabel>regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of basophil degranulation&apos; SubClassOf &apos;regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903583</classIRI>
<classLabel>positive regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of basophil degranulation&apos; SubClassOf &apos;positive regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903582</classIRI>
<classLabel>negative regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of basophil degranulation&apos; SubClassOf &apos;negative regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090508</classIRI>
<classLabel>phenylethylamine biosynthetic process involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;phenylethylamine biosynthetic process involved in synaptic transmission&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090507</classIRI>
<classLabel>phenylethylamine metabolic process involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;phenylethylamine metabolic process involved in synaptic transmission&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008947</classIRI>
<classLabel>respiratory primordium</classLabel>
<deletedAxiom>&apos;respiratory primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903702</classIRI>
<classLabel>esophagus development</classLabel>
<deletedAxiom>&apos;esophagus development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;esophagus development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000084</classIRI>
<classLabel>plant sperm cell</classLabel>
<newAxiom>&apos;plant sperm cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000033</classIRI>
<classLabel>trypomastigote stage</classLabel>
<deletedAxiom>&apos;trypomastigote stage&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Trypanosoma&apos;</deletedAxiom>
<newAxiom>&apos;trypomastigote stage&apos; SubClassOf &apos;in taxon&apos; some &apos;Trypanosoma&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090419</classIRI>
<classLabel>negative regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000332</classIRI>
<classLabel>epidermal pavement cell</classLabel>
<newAxiom>&apos;epidermal pavement cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000351</classIRI>
<classLabel>guard mother cell</classLabel>
<newAxiom>&apos;guard mother cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016428</classIRI>
<classLabel>tRNA (cytosine-5-)-methyltransferase activity</classLabel>
<newAxiom>&apos;tRNA (cytosine-5-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytosine-5-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5-methylcytidine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytosine-5-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytosine-5-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytosine-5-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;cytidine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018227</classIRI>
<classLabel>pulmonary lymphatic vessel</classLabel>
<newAxiom>&apos;pulmonary lymphatic vessel&apos; SubClassOf &apos;has_part&apos; some &apos;respiratory system lymphatic vessel endothelium&apos;</newAxiom>
<newAxiom>&apos;pulmonary lymphatic vessel&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0018226</classIRI>
<classLabel>pulmonary part of lymphatic system</classLabel>
<newAxiom>&apos;pulmonary part of lymphatic system&apos; SubClassOf &apos;protein-containing material entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006990</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;endoplasmic reticulum unfolded protein response&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; SubClassOf &apos;part_of&apos; some &apos;endoplasmic reticulum unfolded protein response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008870</classIRI>
<classLabel>pulmonary alveolar parenchyma</classLabel>
<newAxiom>&apos;pulmonary alveolar parenchyma&apos; SubClassOf &apos;has_part&apos; some &apos;type II pneumocyte&apos;</newAxiom>
<newAxiom>&apos;pulmonary alveolar parenchyma&apos; SubClassOf &apos;has_part&apos; some &apos;type I pneumocyte&apos;</newAxiom>
<newAxiom>&apos;pulmonary alveolar parenchyma&apos; SubClassOf &apos;has_part&apos; some &apos;lung pericyte&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008874</classIRI>
<classLabel>pulmonary acinus</classLabel>
<deletedAxiom>&apos;pulmonary acinus&apos; SubClassOf &apos;pulmonary lobule&apos;</deletedAxiom>
<newAxiom>&apos;pulmonary acinus&apos; SubClassOf &apos;part_of&apos; some http://purl.obolibrary.org/obo/UBERON_0010369</newAxiom>
<newAxiom>&apos;pulmonary acinus&apos; SubClassOf &apos;connected to&apos; some &apos;terminal bronchiole&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180019</classIRI>
<classLabel>Knl1/Spc105 complex</classLabel>
<deletedAxiom>&apos;Knl1/Spc105 complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;part_of&apos; some &apos;outer kinetochore&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090215</classIRI>
<classLabel>regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090217</classIRI>
<classLabel>negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;negatively regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;negative regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;negatively regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090216</classIRI>
<classLabel>positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (&apos;positively regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;positively regulates&apos; some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090282</classIRI>
<classLabel>positive regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000282</classIRI>
<classLabel>trichome</classLabel>
<newAxiom>&apos;trichome&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000293</classIRI>
<classLabel>guard cell</classLabel>
<newAxiom>&apos;guard cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000256</classIRI>
<classLabel>root hair cell</classLabel>
<newAxiom>&apos;root hair cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000263</classIRI>
<classLabel>non-hair root epidermal cell</classLabel>
<newAxiom>&apos;non-hair root epidermal cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0000262</classIRI>
<classLabel>trichoblast</classLabel>
<newAxiom>&apos;trichoblast&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008781</classIRI>
<classLabel>blastodisc derived epiblast</classLabel>
<deletedAxiom>&apos;blastodisc derived epiblast&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008780</classIRI>
<classLabel>inner cell mass derived epiblast</classLabel>
<deletedAxiom>&apos;inner cell mass derived epiblast&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090172</classIRI>
<classLabel>microtubule cytoskeleton organization involved in homologous chromosome segregation</classLabel>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; EquivalentTo &apos;microtubule cytoskeleton organization&apos; and (&apos;part_of&apos; some &apos;homologous chromosome segregation&apos;)</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf &apos;meiotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf &apos;microtubule cytoskeleton organization&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf &apos;part_of&apos; some &apos;homologous chromosome segregation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004242</classIRI>
<classLabel>bronchus smooth muscle</classLabel>
<newAxiom>&apos;bronchus smooth muscle&apos; SubClassOf &apos;has_part&apos; some &apos;bronchial smooth muscle cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016156</classIRI>
<classLabel>fumarate reductase (NADH) activity</classLabel>
<deletedAxiom>&apos;fumarate reductase (NADH) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;fumarate reductase (NADH) activity&apos; SubClassOf &apos;succinate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000323</classIRI>
<classLabel>Trypanosomatida procyclic stage</classLabel>
<deletedAxiom>&apos;Trypanosomatida procyclic stage&apos; EquivalentTo (&apos;has_part&apos; some &apos;cell division&apos;) and (&apos;occurs in&apos; some 
(&apos;Phlebotominae midgut&apos; or &apos;Glossina midgut&apos;)) and (&apos;only_in_taxon&apos; some &apos;Trypanosomatidae&apos;)</deletedAxiom>
<newAxiom>&apos;Trypanosomatida procyclic stage&apos; EquivalentTo &apos;parasite lifecycle stage&apos; and (&apos;has_part&apos; some &apos;cell division&apos;) and (&apos;occurs in&apos; some 
(&apos;Phlebotominae midgut&apos; or &apos;Glossina midgut&apos;)) and (&apos;in taxon&apos; some &apos;Trypanosomatidae&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000322</classIRI>
<classLabel>Trypanosomatida metacyclic stage</classLabel>
<deletedAxiom>&apos;Trypanosomatida metacyclic stage&apos; EquivalentTo (&apos;realizes&apos; some http://purl.obolibrary.org/obo/IDO_0000404) and (&apos;only_in_taxon&apos; some &apos;Trypanosomatidae&apos;)</deletedAxiom>
<newAxiom>&apos;Trypanosomatida metacyclic stage&apos; EquivalentTo &apos;parasite lifecycle stage&apos; and (&apos;realizes&apos; some http://purl.obolibrary.org/obo/IDO_0000404) and (&apos;in taxon&apos; some &apos;Trypanosomatidae&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0020003</classIRI>
<classLabel>plant ovule</classLabel>
<newAxiom>&apos;plant ovule&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090086</classIRI>
<classLabel>negative regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;negative regulation of protein deubiquitination&apos; SubClassOf &apos;negative regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090085</classIRI>
<classLabel>regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;regulation of protein deubiquitination&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004198</classIRI>
<classLabel>comma-shaped body</classLabel>
<deletedAxiom>&apos;comma-shaped body&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004199</classIRI>
<classLabel>S-shaped body</classLabel>
<deletedAxiom>&apos;S-shaped body&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031626</classIRI>
<classLabel>beta-endorphin binding</classLabel>
<deletedAxiom>&apos;beta-endorphin binding&apos; SubClassOf &apos;neurotransmitter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004139</classIRI>
<classLabel>cardiogenic plate</classLabel>
<deletedAxiom>&apos;cardiogenic plate&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0020108</classIRI>
<classLabel>suspensor</classLabel>
<newAxiom>&apos;suspensor&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000181</classIRI>
<classLabel>parasite lifecycle stage</classLabel>
<deletedAxiom>&apos;parasite lifecycle stage&apos; EquivalentTo &apos;life cycle stage&apos; and (&apos;only_in_taxon&apos; some &apos;parasite organism&apos;)</deletedAxiom>
<newAxiom>&apos;parasite lifecycle stage&apos; EquivalentTo &apos;life cycle stage&apos; and (&apos;in taxon&apos; some &apos;parasite organism&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004068</classIRI>
<classLabel>medial nasal prominence</classLabel>
<deletedAxiom>&apos;medial nasal prominence&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004067</classIRI>
<classLabel>lateral nasal prominence</classLabel>
<deletedAxiom>&apos;lateral nasal prominence&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004016</classIRI>
<classLabel>dermatome</classLabel>
<deletedAxiom>&apos;dermatome&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004035</classIRI>
<classLabel>cortical subplate</classLabel>
<deletedAxiom>&apos;cortical subplate&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006581</classIRI>
<classLabel>acetylcholine catabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004040</classIRI>
<classLabel>cortical intermediate zone</classLabel>
<deletedAxiom>&apos;cortical intermediate zone&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006589</classIRI>
<classLabel>octopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;octopamine biosynthetic process&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000151</classIRI>
<classLabel>promastigote stage</classLabel>
<deletedAxiom>&apos;promastigote stage&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Trypanosomatidae&apos;</deletedAxiom>
<newAxiom>&apos;promastigote stage&apos; SubClassOf &apos;in taxon&apos; some &apos;Trypanosomatidae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/OPL_0000114</classIRI>
<classLabel>amastigote stage</classLabel>
<deletedAxiom>&apos;amastigote stage&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;parasite organism&apos;</deletedAxiom>
<newAxiom>&apos;amastigote stage&apos; SubClassOf &apos;in taxon&apos; some &apos;parasite organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031419</classIRI>
<classLabel>cobalamin binding</classLabel>
<newAxiom>&apos;cobalamin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006349</classIRI>
<classLabel>regulation of gene expression by genomic imprinting</classLabel>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; EquivalentTo &apos;epigenetic regulation of gene expression&apos; and (&apos;has_part&apos; some &apos;genomic imprinting&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; SubClassOf &apos;epigenetic regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; SubClassOf &apos;has_part&apos; some &apos;genomic imprinting&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031262</classIRI>
<classLabel>Ndc80 complex</classLabel>
<deletedAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;capable of&apos; some &apos;microtubule plus-end binding&apos;</deletedAxiom>
<deletedAxiom>&apos;Ndc80 complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (&apos;part_of&apos; some &apos;outer kinetochore&apos;) and (&apos;capable of&apos; some &apos;microtubule plus-end binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;Knl1/Spc105 complex&apos;</deletedAxiom>
<newAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;part_of&apos; some &apos;outer kinetochore&apos;</newAxiom>
<newAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004516</classIRI>
<classLabel>smooth muscle tissue of terminal bronchiole</classLabel>
<newAxiom>&apos;smooth muscle tissue of terminal bronchiole&apos; SubClassOf &apos;has_part&apos; some &apos;bronchiolar smooth muscle cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004536</classIRI>
<classLabel>lymph vasculature</classLabel>
<deletedAxiom>&apos;lymph vasculature&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021818</classIRI>
<classLabel>modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration</classLabel>
<deletedAxiom>&apos;modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration&apos; SubClassOf &apos;part_of&apos; some &apos;cell motility involved in cerebral cortex radial glia guided migration&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration&apos; SubClassOf &apos;actin cytoskeleton organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031210</classIRI>
<classLabel>phosphatidylcholine binding</classLabel>
<deletedAxiom>&apos;phosphatidylcholine binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080188</classIRI>
<classLabel>gene silencing by RNA-directed DNA methylation</classLabel>
<newAxiom>&apos;gene silencing by RNA-directed DNA methylation&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Viridiplantae&apos;</newAxiom>
<newAxiom>&apos;gene silencing by RNA-directed DNA methylation&apos; SubClassOf &apos;in taxon&apos; only &apos;Viridiplantae&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006127</classIRI>
<classLabel>glycerophosphate shuttle</classLabel>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;has_part&apos; some &apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has_part&apos; some &apos;glycerol-3-phosphate dehydrogenase [NAD(P)+] activity&apos;) and (&apos;has_part&apos; some &apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos;) and (&apos;has_participant&apos; some &apos;sn-glycerol 3-phosphate(2-)&apos;) and (&apos;has input&apos; some &apos;NADH(2-)&apos;) and (&apos;has output&apos; some &apos;NAD(1-)&apos;) and (&apos;has primary input or output&apos; some &apos;glycerone phosphate(2-)&apos;)</deletedAxiom>
<newAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;has_part&apos; some &apos;glycerol-3-phosphate dehydrogenase (quinone) activity&apos;</newAxiom>
<newAxiom>&apos;glycerophosphate shuttle&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has_part&apos; some &apos;glycerol-3-phosphate dehydrogenase (quinone) activity&apos;) and (&apos;has_part&apos; some &apos;glycerol-3-phosphate dehydrogenase [NAD(P)+] activity&apos;) and (&apos;has_participant&apos; some &apos;sn-glycerol 3-phosphate(2-)&apos;) and (&apos;has input&apos; some &apos;NADH(2-)&apos;) and (&apos;has output&apos; some &apos;NAD(1-)&apos;) and (&apos;has primary input or output&apos; some &apos;glycerone phosphate(2-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031077</classIRI>
<classLabel>post-embryonic camera-type eye development</classLabel>
<deletedAxiom>&apos;post-embryonic camera-type eye development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070646</classIRI>
<classLabel>protein modification by small protein removal</classLabel>
<deletedAxiom>&apos;protein modification by small protein removal&apos; SubClassOf &apos;proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031087</classIRI>
<classLabel>deadenylation-independent decapping of nuclear-transcribed mRNA</classLabel>
<deletedAxiom>&apos;deadenylation-independent decapping of nuclear-transcribed mRNA&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008381</classIRI>
<classLabel>mechanosensitive monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
<newAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0005679</classIRI>
<classLabel>epidermis</classLabel>
<newAxiom>&apos;epidermis&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008292</classIRI>
<classLabel>acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;acetylcholine biosynthetic process&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008291</classIRI>
<classLabel>acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine metabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033265</classIRI>
<classLabel>choline binding</classLabel>
<deletedAxiom>&apos;choline binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141077</classIRI>
<classLabel>suppression of host interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression of host interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of cytokine-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141066</classIRI>
<classLabel>disruption of host extracellular matrix</classLabel>
<newAxiom>&apos;disruption of host extracellular matrix&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141006</classIRI>
<classLabel>piRNA-mediated retrotransposon silencing by heterochromatin formation</classLabel>
<newAxiom>&apos;piRNA-mediated retrotransposon silencing by heterochromatin formation&apos; SubClassOf &apos;piRNA-mediated heterochromatin formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141009</classIRI>
<classLabel>piRNA-mediated retrotransposon silencing by mRNA destabilization</classLabel>
<newAxiom>&apos;piRNA-mediated retrotransposon silencing by mRNA destabilization&apos; SubClassOf &apos;piRNA-mediated gene silencing by mRNA destabilization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141014</classIRI>
<classLabel>ribosome hibernation</classLabel>
<deletedAxiom>&apos;ribosome hibernation&apos; SubClassOf &apos;negative regulation of ribosome biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;ribosome hibernation&apos; SubClassOf &apos;negative regulation of translation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008173</classIRI>
<classLabel>RNA methyltransferase activity</classLabel>
<deletedAxiom>&apos;RNA methyltransferase activity&apos; SubClassOf &apos;part_of&apos; some &apos;RNA methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008175</classIRI>
<classLabel>tRNA methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA methyltransferase activity&apos; SubClassOf &apos;part_of&apos; some &apos;tRNA methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008177</classIRI>
<classLabel>succinate dehydrogenase (ubiquinone) activity</classLabel>
<deletedAxiom>&apos;succinate dehydrogenase (ubiquinone) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013526</classIRI>
<classLabel>otocyst lumen</classLabel>
<deletedAxiom>&apos;otocyst lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047780</classIRI>
<classLabel>citrate dehydratase activity</classLabel>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;has_part&apos; some &apos;aconitate hydratase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;cis-aconitate(3-)&apos;</deletedAxiom>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;citrate(3-)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0005029</classIRI>
<classLabel>root primordium</classLabel>
<newAxiom>&apos;root primordium&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047671</classIRI>
<classLabel>anthranilate adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;anthranilate adenylyltransferase activity&apos; SubClassOf &apos;adenylyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;anthranilate adenylyltransferase activity&apos; SubClassOf &apos;acid-amino acid ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072570</classIRI>
<classLabel>ADP-D-ribose binding</classLabel>
<deletedAxiom>&apos;ADP-D-ribose binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072487</classIRI>
<classLabel>MSL complex</classLabel>
<newAxiom>&apos;MSL complex&apos; SubClassOf &apos;in taxon&apos; only &apos;Metazoa&apos;</newAxiom>
<newAxiom>&apos;MSL complex&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Metazoa&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106340</classIRI>
<classLabel>tRNA (guanosine 34-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;guanosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2&apos;-O-methylguanosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106339</classIRI>
<classLabel>tRNA (cytidine 32-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;guanosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Archaea&apos;)</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Archaea&apos;))</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; DisjointWith &apos;in taxon&apos; some &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2&apos;-O-methylguanosine 5&apos;-monophosphate(1-) residue&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106335</classIRI>
<classLabel>tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003887</classIRI>
<classLabel>intraembryonic coelom</classLabel>
<deletedAxiom>&apos;intraembryonic coelom&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003886</classIRI>
<classLabel>future coelemic cavity lumen</classLabel>
<deletedAxiom>&apos;future coelemic cavity lumen&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013238</classIRI>
<classLabel>future glans</classLabel>
<deletedAxiom>&apos;future glans&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0013241</classIRI>
<classLabel>embryonic urethral groove</classLabel>
<deletedAxiom>&apos;embryonic urethral groove&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072328</classIRI>
<classLabel>alkene binding</classLabel>
<deletedAxiom>&apos;alkene binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;alkene&apos;)</deletedAxiom>
<deletedAxiom>&apos;alkene binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;alkene binding&apos; EquivalentTo &apos;small molecule binding&apos; and (&apos;has input&apos; some &apos;alkene&apos;)</newAxiom>
<newAxiom>&apos;alkene binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047388</classIRI>
<classLabel>[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase</classLabel>
<deletedAxiom>&apos;[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase&apos; SubClassOf &apos;phosphoric diester hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025059</classIRI>
<classLabel>portion of ground tissue</classLabel>
<newAxiom>&apos;portion of ground tissue&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025074</classIRI>
<classLabel>embryo sac</classLabel>
<newAxiom>&apos;embryo sac&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106080</classIRI>
<classLabel>GATOR1 complex binding</classLabel>
<newAxiom>&apos;GATOR1 complex binding&apos; SubClassOf &apos;has input&apos; some &apos;GATOR1 complex&apos;</newAxiom>
<newAxiom>&apos;GATOR1 complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;GATOR1 complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106059</classIRI>
<classLabel>tRNA (cytidine 56-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;in taxon&apos; only &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;only_in_taxon&apos; some &apos;Archaea&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047151</classIRI>
<classLabel>methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity</classLabel>
<deletedAxiom>&apos;methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025268</classIRI>
<classLabel>fruit septum</classLabel>
<newAxiom>&apos;fruit septum&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025262</classIRI>
<classLabel>plant ovary septum</classLabel>
<newAxiom>&apos;plant ovary septum&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025281</classIRI>
<classLabel>pollen</classLabel>
<newAxiom>&apos;pollen&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025128</classIRI>
<classLabel>phyllome primordium</classLabel>
<newAxiom>&apos;phyllome primordium&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0025195</classIRI>
<classLabel>pollen tube cell</classLabel>
<newAxiom>&apos;pollen tube cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0005849</classIRI>
<classLabel>primary xylem</classLabel>
<newAxiom>&apos;primary xylem&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0008281</classIRI>
<classLabel>tooth bud</classLabel>
<deletedAxiom>&apos;tooth bud&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052906</classIRI>
<classLabel>tRNA (guanine(37)-N(1))-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine(37)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanine(37)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052905</classIRI>
<classLabel>tRNA (guanine(9)-N(1))-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine(9)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanine(9)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052895</classIRI>
<classLabel>N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity</classLabel>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3-ammoniopropanal&apos;</newAxiom>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydrogen peroxide&apos;</newAxiom>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(1)-acetylsperminium(3+)&apos;</newAxiom>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;dioxygen&apos;</newAxiom>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;N(1)-acetylspermidinium(2+)&apos;</newAxiom>
<newAxiom>&apos;N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052894</classIRI>
<classLabel>norspermine:oxygen oxidoreductase activity</classLabel>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;bis(3-azaniumylpropyl)azanium&apos;</newAxiom>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydrogen peroxide&apos;</newAxiom>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3-ammoniopropanal&apos;</newAxiom>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</newAxiom>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3,3,3-tetraminium(4+)&apos;</newAxiom>
<newAxiom>&apos;norspermine:oxygen oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;dioxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003995</classIRI>
<classLabel>acyl-CoA dehydrogenase activity</classLabel>
<newAxiom>&apos;acyl-CoA dehydrogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;FAD(3-)&apos;</newAxiom>
<newAxiom>&apos;acyl-CoA dehydrogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;3-substituted propionyl-CoA(4-)&apos;</newAxiom>
<newAxiom>&apos;acyl-CoA dehydrogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;FADH2(2-)&apos;</newAxiom>
<newAxiom>&apos;acyl-CoA dehydrogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2,3-trans-enoyl CoA(4-)&apos;</newAxiom>
<newAxiom>&apos;acyl-CoA dehydrogenase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903003</classIRI>
<classLabel>positive regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of protein deubiquitination&apos; SubClassOf &apos;positive regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062153</classIRI>
<classLabel>C5-methylcytidine-containing RNA binding</classLabel>
<deletedAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf &apos;RNA binding&apos;</deletedAxiom>
<newAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf &apos;protein-RNA adaptor activity&apos;</newAxiom>
<newAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf &apos;has_part&apos; some &apos;RNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062156</classIRI>
<classLabel>mitochondrial ATP-gated potassium channel activity</classLabel>
<deletedAxiom>&apos;mitochondrial ATP-gated potassium channel activity&apos; EquivalentTo &apos;ligand-gated channel activity&apos; and (&apos;regulated by&apos; some &apos;ATP binding&apos;) and (&apos;results in transport across&apos; some &apos;mitochondrial inner membrane&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;)</deletedAxiom>
<newAxiom>&apos;mitochondrial ATP-gated potassium channel activity&apos; EquivalentTo &apos;gated channel activity&apos; and (&apos;results in transport across&apos; some &apos;mitochondrial inner membrane&apos;) and (&apos;has primary input&apos; some &apos;potassium(1+)&apos;) and (http://purl.obolibrary.org/obo/RO_0012001 some &apos;ATP(4-)&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052633</classIRI>
<classLabel>isocitrate hydro-lyase (cis-aconitate-forming) activity</classLabel>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;D-threo-isocitrate(3-)&apos;</deletedAxiom>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;cis-aconitate(3-)&apos;</deletedAxiom>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;has_part&apos; some &apos;aconitate hydratase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052666</classIRI>
<classLabel>tRNA (cytosine-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052665</classIRI>
<classLabel>tRNA (uracil-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (uracil-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (uracil-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-homocysteine zwitterion&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (uracil-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;uridine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (uracil-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;S-adenosyl-L-methionine zwitterion&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (uracil-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;2&apos;-O-methyluridine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062094</classIRI>
<classLabel>stomach development</classLabel>
<deletedAxiom>&apos;stomach development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;stomach development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062093</classIRI>
<classLabel>lysophagy</classLabel>
<deletedAxiom>&apos;lysophagy&apos; SubClassOf &apos;has input&apos; some &apos;lysosome&apos;</deletedAxiom>
<deletedAxiom>&apos;lysophagy&apos; EquivalentTo &apos;selective autophagy&apos; and (&apos;has input&apos; some &apos;lysosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;lysophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;lysophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007379</classIRI>
<classLabel>shelled egg</classLabel>
<deletedAxiom>&apos;shelled egg&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003676</classIRI>
<classLabel>nucleic acid binding</classLabel>
<deletedAxiom>&apos;nucleic acid binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052553</classIRI>
<classLabel>perturbation of host immune response</classLabel>
<newAxiom>&apos;perturbation of host immune response&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052590</classIRI>
<classLabel>sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity</classLabel>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos; SubClassOf &apos;glycerol-3-phosphate dehydrogenase (quinone) activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052591</classIRI>
<classLabel>sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity</classLabel>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;sn-glycerol 3-phosphate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;ubiquinone-8&apos;</deletedAxiom>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;glycerone phosphate(2-)&apos;</deletedAxiom>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;ubiquinol-8&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007106</classIRI>
<classLabel>chorionic villus</classLabel>
<deletedAxiom>&apos;chorionic villus&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007128</classIRI>
<classLabel>glomeral mesenchyme</classLabel>
<deletedAxiom>&apos;glomeral mesenchyme&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007144</classIRI>
<classLabel>embryonic post-anal tail</classLabel>
<deletedAxiom>&apos;embryonic post-anal tail&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902097</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; SubClassOf &apos;part_of&apos; some &apos;defense response to Gram-negative bacterium&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (&apos;part_of&apos; some &apos;defense response to Gram-negative bacterium&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_64091</classIRI>
<classLabel>Halobacterium salinarum NRC-1</classLabel>
<deletedAxiom>&apos;Halobacterium salinarum NRC-1&apos; SubClassOf &apos;Halobacterium salinarum&apos;</deletedAxiom>
<newAxiom>&apos;Halobacterium salinarum NRC-1&apos; SubClassOf http://purl.obolibrary.org/obo/NCBITaxon_2886895</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990760</classIRI>
<classLabel>osmolarity-sensing monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;osmolarity-sensing monoatomic cation channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;osmolarity-sensing monoatomic cation channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001147</classIRI>
<classLabel>camalexin binding</classLabel>
<deletedAxiom>&apos;camalexin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007779</classIRI>
<classLabel>transudate</classLabel>
<deletedAxiom>&apos;transudate&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007689</classIRI>
<classLabel>thyroid diverticulum</classLabel>
<deletedAxiom>&apos;thyroid diverticulum&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042729</classIRI>
<classLabel>DASH complex</classLabel>
<deletedAxiom>&apos;DASH complex&apos; SubClassOf &apos;Knl1/Spc105 complex&apos;</deletedAxiom>
<newAxiom>&apos;DASH complex&apos; SubClassOf &apos;part_of&apos; some &apos;outer kinetochore&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042783</classIRI>
<classLabel>evasion of host immune response</classLabel>
<deletedAxiom>&apos;evasion of host immune response&apos; SubClassOf &apos;response to host immune response&apos;</deletedAxiom>
<newAxiom>&apos;evasion of host immune response&apos; SubClassOf &apos;perturbation of host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052110</classIRI>
<classLabel>occlusion by symbiont of host vascular system</classLabel>
<deletedAxiom>&apos;occlusion by symbiont of host vascular system&apos; SubClassOf &apos;disruption by symbiont of host anatomical structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052112</classIRI>
<classLabel>occlusion by symbiont of host xylem</classLabel>
<deletedAxiom>&apos;occlusion by symbiont of host xylem&apos; SubClassOf &apos;occlusion by symbiont of host vascular system&apos;</deletedAxiom>
<newAxiom>&apos;occlusion by symbiont of host xylem&apos; SubClassOf &apos;disruption by symbiont of host anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052183</classIRI>
<classLabel>disruption of symbiont cellular component</classLabel>
<deletedAxiom>&apos;disruption of symbiont cellular component&apos; SubClassOf &apos;disruption of cellular anatomical structure in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption of symbiont cellular component&apos; SubClassOf &apos;biological process involved in interaction with symbiont&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052150</classIRI>
<classLabel>modulation by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;regulates&apos; some &apos;apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host apoptotic process&apos; SubClassOf &apos;regulation of apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052151</classIRI>
<classLabel>positive regulation by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; SubClassOf &apos;positive regulation of apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;positively regulates&apos; some &apos;apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; SubClassOf &apos;induction by symbiont of host programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052163</classIRI>
<classLabel>symbiont defense to host-produced nitric oxide</classLabel>
<deletedAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;symbiont defense to host-produced reactive oxygen species&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;cellular response to nitrosative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052078</classIRI>
<classLabel>symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902444</classIRI>
<classLabel>riboflavin binding</classLabel>
<deletedAxiom>&apos;riboflavin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042608</classIRI>
<classLabel>T cell receptor binding</classLabel>
<deletedAxiom>&apos;T cell receptor binding&apos; EquivalentTo &apos;protein-containing complex binding&apos; and (&apos;has input&apos; some &apos;T cell receptor complex&apos;)</deletedAxiom>
<newAxiom>&apos;T cell receptor binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;T cell receptor complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052009</classIRI>
<classLabel>disruption by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;modification by symbiont of host cell wall&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;disruption of cell wall in another organism&apos;</newAxiom>
<newAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052020</classIRI>
<classLabel>modification by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052040</classIRI>
<classLabel>modulation by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;regulates&apos; some &apos;programmed cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host programmed cell death&apos; SubClassOf &apos;regulates&apos; some &apos;programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052042</classIRI>
<classLabel>induction by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;induction by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;positively regulates&apos; some &apos;programmed cell death&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052041</classIRI>
<classLabel>suppression by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (&apos;negatively regulates&apos; some &apos;programmed cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host programmed cell death&apos; SubClassOf &apos;negatively regulates&apos; some &apos;programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140884</classIRI>
<classLabel>suppression by virus of host type II interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of type II interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;negatively regulates&apos; some &apos;type II interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032924</classIRI>
<classLabel>activin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;activin receptor signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;activin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_24432</classIRI>
<classLabel>biological role</classLabel>
<deletedAxiom>&apos;biological role&apos; SubClassOf &apos;role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032979</classIRI>
<classLabel>protein insertion into mitochondrial inner membrane from matrix</classLabel>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;inner mitochondrial membrane organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140740</classIRI>
<classLabel>ADP-riboxanase activity</classLabel>
<deletedAxiom>&apos;ADP-riboxanase activity&apos; SubClassOf &apos;part_of&apos; some &apos;post-translational protein modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0006088</classIRI>
<classLabel>primary sporogenous cell</classLabel>
<newAxiom>&apos;primary sporogenous cell&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042166</classIRI>
<classLabel>acetylcholine binding</classLabel>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;neurotransmitter binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042165</classIRI>
<classLabel>neurotransmitter binding</classLabel>
<deletedAxiom>&apos;neurotransmitter binding&apos; SubClassOf &apos;has input&apos; some &apos;substance with neurotransmitter role&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;substance with neurotransmitter role&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007807</classIRI>
<classLabel>connecting stalk vasculature</classLabel>
<deletedAxiom>&apos;connecting stalk vasculature&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0007806</classIRI>
<classLabel>connecting stalk</classLabel>
<deletedAxiom>&apos;connecting stalk&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140587</classIRI>
<classLabel>chromatin loop anchoring activity</classLabel>
<newAxiom>&apos;chromatin loop anchoring activity&apos; SubClassOf &apos;chromatin DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032777</classIRI>
<classLabel>Piccolo NuA4 histone acetyltransferase complex</classLabel>
<deletedAxiom>&apos;Piccolo NuA4 histone acetyltransferase complex&apos; SubClassOf &apos;NuA4 histone acetyltransferase complex&apos;</deletedAxiom>
<newAxiom>&apos;Piccolo NuA4 histone acetyltransferase complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017150</classIRI>
<classLabel>tRNA dihydrouridine synthase activity</classLabel>
<deletedAxiom>&apos;tRNA dihydrouridine synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NADPH(4-)&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA dihydrouridine synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;5,6-dihydrouridine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA dihydrouridine synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;uridine 5&apos;-monophosphate(1-) residue&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA dihydrouridine synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;hydron&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA dihydrouridine synthase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;NADP(3-)&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042138</classIRI>
<classLabel>meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;meiotic DNA double-strand break formation&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<newAxiom>&apos;meiotic DNA double-strand break formation&apos; SubClassOf &apos;DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042137</classIRI>
<classLabel>sequestering of neurotransmitter</classLabel>
<deletedAxiom>&apos;sequestering of neurotransmitter&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042136</classIRI>
<classLabel>neurotransmitter biosynthetic process</classLabel>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; EquivalentTo &apos;biosynthetic process&apos; and (&apos;has primary output&apos; some &apos;substance with neurotransmitter role&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; SubClassOf &apos;has primary output&apos; some &apos;substance with neurotransmitter role&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/PO_0006001</classIRI>
<classLabel>phyllome</classLabel>
<newAxiom>&apos;phyllome&apos; SubClassOf &apos;anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042135</classIRI>
<classLabel>neurotransmitter catabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; EquivalentTo &apos;catabolic process&apos; and (&apos;has primary input&apos; some &apos;substance with neurotransmitter role&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; SubClassOf &apos;has primary input&apos; some &apos;substance with neurotransmitter role&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042133</classIRI>
<classLabel>neurotransmitter metabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf &apos;in taxon&apos; some (not (&apos;Schizosaccharomyces&apos;))</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; DisjointWith &apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf &apos;has primary input or output&apos; some &apos;substance with neurotransmitter role&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf not (&apos;in taxon&apos; some &apos;Schizosaccharomyces&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; EquivalentTo &apos;metabolic process&apos; and (&apos;has primary input or output&apos; some &apos;substance with neurotransmitter role&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003374</classIRI>
<classLabel>chorionic ectoderm</classLabel>
<deletedAxiom>&apos;chorionic ectoderm&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140496</classIRI>
<classLabel>gamma-tubulin complex binding</classLabel>
<newAxiom>&apos;gamma-tubulin complex binding&apos; SubClassOf &apos;has input&apos; some &apos;gamma-tubulin complex&apos;</newAxiom>
<newAxiom>&apos;gamma-tubulin complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;gamma-tubulin complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017041</classIRI>
<classLabel>galactosylgalactosylglucosylceramidase activity</classLabel>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;water&apos;</deletedAxiom>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;alpha-D-galactosyl-(1-4)-beta-D-galactosyl-(1-4)-beta-D-glucosylceramide&apos;</deletedAxiom>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;beta-D-galactosyl-(1-4)-beta-D-glucosyl-(1-1)-N-acylsphingosine&apos;</deletedAxiom>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;has_participant&apos; some &apos;D-galactopyranose&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007504</classIRI>
<classLabel>larval fat body development</classLabel>
<deletedAxiom>&apos;larval fat body development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007508</classIRI>
<classLabel>larval heart development</classLabel>
<deletedAxiom>&apos;larval heart development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140355</classIRI>
<classLabel>cargo receptor ligand activity</classLabel>
<deletedAxiom>&apos;cargo receptor ligand activity&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;cargo receptor ligand activity&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007523</classIRI>
<classLabel>larval visceral muscle development</classLabel>
<deletedAxiom>&apos;larval visceral muscle development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007526</classIRI>
<classLabel>larval somatic muscle development</classLabel>
<deletedAxiom>&apos;larval somatic muscle development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007560</classIRI>
<classLabel>imaginal disc morphogenesis</classLabel>
<deletedAxiom>&apos;imaginal disc morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;imaginal disc morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140272</classIRI>
<classLabel>exogenous protein binding</classLabel>
<deletedAxiom>&apos;exogenous protein binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;exogenous protein binding&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071947</classIRI>
<classLabel>protein deubiquitination involved in ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;protein deubiquitination involved in ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;proteolysis involved in protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071931</classIRI>
<classLabel>positive regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071930</classIRI>
<classLabel>negative regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (&apos;part_of&apos; some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071933</classIRI>
<classLabel>Arp2/3 complex binding</classLabel>
<newAxiom>&apos;Arp2/3 complex binding&apos; SubClassOf &apos;has input&apos; some &apos;Arp2/3 protein complex&apos;</newAxiom>
<newAxiom>&apos;Arp2/3 complex binding&apos; EquivalentTo &apos;binding&apos; and (&apos;has input&apos; some &apos;Arp2/3 protein complex&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003084</classIRI>
<classLabel>heart primordium</classLabel>
<deletedAxiom>&apos;heart primordium&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003080</classIRI>
<classLabel>anterior neural tube</classLabel>
<deletedAxiom>&apos;anterior neural tube&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003082</classIRI>
<classLabel>myotome</classLabel>
<deletedAxiom>&apos;myotome&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003063</classIRI>
<classLabel>prechordal plate</classLabel>
<deletedAxiom>&apos;prechordal plate&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003064</classIRI>
<classLabel>intermediate mesoderm</classLabel>
<deletedAxiom>&apos;intermediate mesoderm&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003068</classIRI>
<classLabel>axial mesoderm</classLabel>
<deletedAxiom>&apos;axial mesoderm&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003076</classIRI>
<classLabel>posterior neural tube</classLabel>
<deletedAxiom>&apos;posterior neural tube&apos; SubClassOf &apos;anatomical entity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046906</classIRI>
<classLabel>tetrapyrrole binding</classLabel>
<deletedAxiom>&apos;tetrapyrrole binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046928</classIRI>
<classLabel>regulation of neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter secretion&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_149682</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_60005380</classIRI>
<classLabel>insect pharynx</classLabel>
<newAxiom>'insect pharynx' SubClassOf 'pharynx'</newAxiom>
<newAxiom>'insect pharynx' SubClassOf 'part_of' some 'digestive tract epithelium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002173</classIRI>
<classLabel>pulmonary alveolar duct</classLabel>
<newAxiom>'pulmonary alveolar duct' SubClassOf 'respiratory tube'</newAxiom>
<newAxiom>'pulmonary alveolar duct' SubClassOf 'part_of' some 'lung'</newAxiom>
<newAxiom>'pulmonary alveolar duct' SubClassOf 'tube'</newAxiom>
<newAxiom>'pulmonary alveolar duct' SubClassOf 'part_of' some 'alveolar system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0002188</classIRI>
<classLabel>respiratory bronchiole</classLabel>
<newAxiom>'respiratory bronchiole' SubClassOf 'distally connected to' some 'pulmonary alveolar duct'</newAxiom>
<newAxiom>'respiratory bronchiole' SubClassOf 'contributes to morphology of' some 'pulmonary acinus'</newAxiom>
<newAxiom>'respiratory bronchiole' SubClassOf 'proximally connected to' some 'terminal bronchiole'</newAxiom>
<newAxiom>'respiratory bronchiole' SubClassOf 'part_of' some 'pulmonary acinus'</newAxiom>
<newAxiom>'respiratory bronchiole' SubClassOf 'bronchiole'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_188470</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/NCBITaxon_2886895</classIRI>
<classLabel>Halobacterium salinarum NRC-34001</classLabel>
<newAxiom>'Halobacterium salinarum NRC-34001' SubClassOf 'in taxon' some 'Halobacterium salinarum NRC-34001'</newAxiom>
<newAxiom>'Halobacterium salinarum NRC-34001' SubClassOf 'Halobacterium salinarum'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0017000</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_85936</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0001955</classIRI>
<classLabel>epithelium of respiratory bronchiole</classLabel>
<newAxiom>'epithelium of respiratory bronchiole' EquivalentTo 'epithelium' and ('part_of' some 'respiratory bronchiole')</newAxiom>
<newAxiom>'epithelium of respiratory bronchiole' SubClassOf 'has_part' some 'club cell'</newAxiom>
<newAxiom>'epithelium of respiratory bronchiole' SubClassOf 'epithelium of bronchiole'</newAxiom>
<newAxiom>'epithelium of respiratory bronchiole' SubClassOf 'part_of' some 'respiratory bronchiole'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_8600017</classIRI>
<classLabel>bronchopulmonary segment</classLabel>
<newAxiom>'bronchopulmonary segment' SubClassOf 'contributes to morphology of' some 'lobe of lung'</newAxiom>
<newAxiom>'bronchopulmonary segment' SubClassOf 'organ subunit'</newAxiom>
<newAxiom>'bronchopulmonary segment' SubClassOf 'part_of' some 'lobe of lung'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CL_0002208</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0005041</classIRI>
<classLabel>mucosa of respiratory bronchiole</classLabel>
<newAxiom>'mucosa of respiratory bronchiole' SubClassOf 'mucosa of bronchiole'</newAxiom>
<newAxiom>'mucosa of respiratory bronchiole' EquivalentTo 'mucosa' and ('part_of' some 'respiratory bronchiole')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0015232</classIRI>
<classLabel>nematode pharynx</classLabel>
<newAxiom>'nematode pharynx' SubClassOf 'part_of' some 'digestive tract'</newAxiom>
<newAxiom>'nematode pharynx' SubClassOf 'only_in_taxon' some 'Nematoda'</newAxiom>
<newAxiom>'nematode pharynx' SubClassOf 'pharynx'</newAxiom>
<newAxiom>'nematode pharynx' SubClassOf 'digestive system element'</newAxiom>
<newAxiom>'nematode pharynx' SubClassOf 'organ'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160087</classIRI>
<classLabel>spermatid cytoplasm removal during spermiation of flagellated sperm</classLabel>
<newAxiom>'spermatid cytoplasm removal during spermiation of flagellated sperm' SubClassOf 'developmental process involved in reproduction'</newAxiom>
<newAxiom>'spermatid cytoplasm removal during spermiation of flagellated sperm' SubClassOf 'part_of' some 'spermatogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160086</classIRI>
<classLabel>protein localization to polar microtubule</classLabel>
<newAxiom>'protein localization to polar microtubule' SubClassOf 'has target end location' some 'polar microtubule'</newAxiom>
<newAxiom>'protein localization to polar microtubule' SubClassOf 'protein localization to spindle microtubule'</newAxiom>
<newAxiom>'protein localization to polar microtubule' EquivalentTo 'protein localization' and ('has target end location' some 'polar microtubule')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160083</classIRI>
<classLabel>exhausted T cell differentiation</classLabel>
<newAxiom>'exhausted T cell differentiation' EquivalentTo 'cell differentiation' and ('results in acquisition of features of' some 'exhausted T cell')</newAxiom>
<newAxiom>'exhausted T cell differentiation' SubClassOf 'results in acquisition of features of' some 'exhausted T cell'</newAxiom>
<newAxiom>'exhausted T cell differentiation' SubClassOf 'T cell differentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160089</classIRI>
<classLabel>internal N(7)-methylguanine-containing RNA reader activity</classLabel>
<newAxiom>'internal N(7)-methylguanine-containing RNA reader activity' SubClassOf 'protein-RNA adaptor activity'</newAxiom>
<newAxiom>'internal N(7)-methylguanine-containing RNA reader activity' SubClassOf 'has_part' some 'RNA binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160091</classIRI>
<classLabel>spliceosome-depend formation of circular RNA</classLabel>
<newAxiom>'spliceosome-depend formation of circular RNA' SubClassOf 'mRNA splicing, via spliceosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160090</classIRI>
<classLabel>internal mRNA (guanine-N7-)-methyltransferase activity</classLabel>
<newAxiom>'internal mRNA (guanine-N7-)-methyltransferase activity' SubClassOf 'mRNA methyltransferase activity'</newAxiom>
<newAxiom>'internal mRNA (guanine-N7-)-methyltransferase activity' SubClassOf 'part_of' some 'RNA (guanine-N7)-methylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160097</classIRI>
<classLabel>reverse gyrase activity</classLabel>
<newAxiom>'reverse gyrase activity' SubClassOf 'DNA topoisomerase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160096</classIRI>
<classLabel>nematode pharyngeal muscle development</classLabel>
<newAxiom>'nematode pharyngeal muscle development' SubClassOf 'part_of' some 'nematode pharynx development'</newAxiom>
<newAxiom>'nematode pharyngeal muscle development' SubClassOf 'muscle organ development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160095</classIRI>
<classLabel>insect pharynx development</classLabel>
<newAxiom>'insect pharynx development' EquivalentTo 'anatomical structure development' and ('results in development of' some 'insect pharynx')</newAxiom>
<newAxiom>'insect pharynx development' SubClassOf 'results in development of' some 'insect pharynx'</newAxiom>
<newAxiom>'insect pharynx development' SubClassOf 'pharynx development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160094</classIRI>
<classLabel>nematode pharynx development</classLabel>
<newAxiom>'nematode pharynx development' EquivalentTo 'anatomical structure development' and ('results in development of' some 'nematode pharynx')</newAxiom>
<newAxiom>'nematode pharynx development' SubClassOf 'results in development of' some 'nematode pharynx'</newAxiom>
<newAxiom>'nematode pharynx development' SubClassOf 'pharynx development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160093</classIRI>
<classLabel>chordate pharynx development</classLabel>
<newAxiom>'chordate pharynx development' SubClassOf 'pharynx development'</newAxiom>
<newAxiom>'chordate pharynx development' EquivalentTo 'anatomical structure development' and ('results in development of' some 'chordate pharynx')</newAxiom>
<newAxiom>'chordate pharynx development' SubClassOf 'results in development of' some 'chordate pharynx'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160092</classIRI>
<classLabel>hemozoin formation complex</classLabel>
<newAxiom>'hemozoin formation complex' SubClassOf 'in taxon' only 'Plasmodium'</newAxiom>
<newAxiom>'hemozoin formation complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'hemozoin formation complex' SubClassOf 'only_in_taxon' some 'Plasmodium'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/CHEBI_142864</classIRI>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160107</classIRI>
<classLabel>tRNA (adenine(58)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'N(1)-methyladenosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'adenosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160106</classIRI>
<classLabel>tRNA (adenine(9)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'N(1)-methyladenosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'adenosine 5'-monophosphate(1-) residue'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160105</classIRI>
<classLabel>tRNA (adenine(22)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'adenosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'N(1)-methyladenosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160104</classIRI>
<classLabel>tRNA (guanine(26)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'guanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'N(2),N(2)-dimethylguanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160103</classIRI>
<classLabel>tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'N(2),N(2)-dimethylguanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'guanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160102</classIRI>
<classLabel>tRNA (guanine(10)-N2)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'has_participant' some 'guanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'has_participant' some 'N(2)-methylguanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160101</classIRI>
<classLabel>tRNA (guanine(10)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'guanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'N(2),N(2)-dimethylguanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160109</classIRI>
<classLabel>plant gross anatomical part developmental process</classLabel>
<newAxiom>'plant gross anatomical part developmental process' SubClassOf 'developmental process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160108</classIRI>
<classLabel>animal gross anatomical part developmental process</classLabel>
<newAxiom>'animal gross anatomical part developmental process' SubClassOf 'developmental process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160110</classIRI>
<classLabel>axonemal microtubule doublet inner sheath</classLabel>
<newAxiom>'axonemal microtubule doublet inner sheath' SubClassOf 'part_of' some 'axonemal outer doublet'</newAxiom>
<newAxiom>'axonemal microtubule doublet inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160115</classIRI>
<classLabel>axonemal microtubule doublet ribbon</classLabel>
<newAxiom>'axonemal microtubule doublet ribbon' SubClassOf 'part_of' some 'axonemal outer doublet'</newAxiom>
<newAxiom>'axonemal microtubule doublet ribbon' SubClassOf 'cellular anatomical entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160114</classIRI>
<classLabel>axonemal microtubule doublet outer junction</classLabel>
<newAxiom>'axonemal microtubule doublet outer junction' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal microtubule doublet outer junction' SubClassOf 'part_of' some 'axonemal outer doublet'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160113</classIRI>
<classLabel>axonemal microtubule doublet inner junction</classLabel>
<newAxiom>'axonemal microtubule doublet inner junction' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal microtubule doublet inner junction' SubClassOf 'part_of' some 'axonemal outer doublet'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160112</classIRI>
<classLabel>axonemal B tubule inner sheath</classLabel>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf 'part_of' some 'axonemal microtubule doublet inner sheath'</newAxiom>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf 'part_of' some 'A axonemal microtubule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160111</classIRI>
<classLabel>axonemal A tubule inner sheath</classLabel>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf 'part_of' some 'A axonemal microtubule'</newAxiom>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf 'part_of' some 'axonemal microtubule doublet inner sheath'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0010369</classIRI>
<classLabel>secondary pulmonary lobule</classLabel>
<newAxiom>'secondary pulmonary lobule' SubClassOf 'part_of' some 'lung parenchyma'</newAxiom>
<newAxiom>'secondary pulmonary lobule' SubClassOf 'pulmonary lobule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170027</classIRI>
<classLabel>SKA complex</classLabel>
<newAxiom>'SKA complex' SubClassOf 'capable of' some 'microtubule plus-end binding'</newAxiom>
<newAxiom>'SKA complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'SKA complex' SubClassOf 'part_of' some 'outer kinetochore'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0004517</classIRI>
<classLabel>smooth muscle tissue of respiratory bronchiole</classLabel>
<newAxiom>'smooth muscle tissue of respiratory bronchiole' SubClassOf 'smooth muscle tissue of bronchiole'</newAxiom>
<newAxiom>'smooth muscle tissue of respiratory bronchiole' EquivalentTo 'smooth muscle tissue' and ('part_of' some 'respiratory bronchiole')</newAxiom>
<newAxiom>'smooth muscle tissue of respiratory bronchiole' SubClassOf 'has_part' some 'bronchiolar smooth muscle cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003537</classIRI>
<classLabel>left lung alveolar duct</classLabel>
<newAxiom>'left lung alveolar duct' EquivalentTo 'pulmonary alveolar duct' and ('part_of' some 'left lung')</newAxiom>
<newAxiom>'left lung alveolar duct' SubClassOf 'pulmonary alveolar duct'</newAxiom>
<newAxiom>'left lung alveolar duct' SubClassOf 'part_of' some 'left lung alveolar system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003536</classIRI>
<classLabel>right lung alveolar duct</classLabel>
<newAxiom>'right lung alveolar duct' EquivalentTo 'pulmonary alveolar duct' and ('part_of' some 'right lung')</newAxiom>
<newAxiom>'right lung alveolar duct' SubClassOf 'pulmonary alveolar duct'</newAxiom>
<newAxiom>'right lung alveolar duct' SubClassOf 'part_of' some 'right lung alveolar system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003543</classIRI>
<classLabel>left lung respiratory bronchiole</classLabel>
<newAxiom>'left lung respiratory bronchiole' SubClassOf 'left lung bronchiole'</newAxiom>
<newAxiom>'left lung respiratory bronchiole' EquivalentTo 'respiratory bronchiole' and ('part_of' some 'left lung')</newAxiom>
<newAxiom>'left lung respiratory bronchiole' SubClassOf 'respiratory bronchiole'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_0003542</classIRI>
<classLabel>right lung respiratory bronchiole</classLabel>
<newAxiom>'right lung respiratory bronchiole' SubClassOf 'respiratory bronchiole'</newAxiom>
<newAxiom>'right lung respiratory bronchiole' SubClassOf 'right lung bronchiole'</newAxiom>
<newAxiom>'right lung respiratory bronchiole' EquivalentTo 'respiratory bronchiole' and ('part_of' some 'right lung')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141105</classIRI>
<classLabel>symbiont-mediated suppression of host toll-like receptor signal transduction</classLabel>
<newAxiom>'symbiont-mediated suppression of host toll-like receptor signal transduction' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141104</classIRI>
<classLabel>symbiont-mediated activation of host G protein-coupled receptor signal transduction</classLabel>
<newAxiom>'symbiont-mediated activation of host G protein-coupled receptor signal transduction' SubClassOf 'perturbation of host G protein-coupled receptor signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141102</classIRI>
<classLabel>tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (uridine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some '5-carboxymethylaminomethyl-2'-O-methyluridine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some '5-carboxymethylaminomethyluridine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141101</classIRI>
<classLabel>tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity</classLabel>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'has_participant' some 'uridine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'has_participant' some '2'-O-methyluridine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'tRNA (uridine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141100</classIRI>
<classLabel>tRNA (guanine(18)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'guanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some '2'-O-methylguanosine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141098</classIRI>
<classLabel>tRNA (cytidine(34)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'cytidine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (cytidine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some '2'-O-methylcytidine 5'-monophosphate(1-) residue'</newAxiom>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-homocysteine zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141097</classIRI>
<classLabel>ligand-activated transcription activator activity</classLabel>
<newAxiom>'ligand-activated transcription activator activity' SubClassOf 'ligand-activated transcription factor activity'</newAxiom>
<newAxiom>'ligand-activated transcription activator activity' SubClassOf 'DNA-binding transcription activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141096</classIRI>
<classLabel>ligand-activated transcription repressor activity</classLabel>
<newAxiom>'ligand-activated transcription repressor activity' SubClassOf 'ligand-activated transcription factor activity'</newAxiom>
<newAxiom>'ligand-activated transcription repressor activity' SubClassOf 'DNA-binding transcription repressor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141095</classIRI>
<classLabel>retrotransposon silencing by DNA methylation-dependent heterochromatin formation</classLabel>
<newAxiom>'retrotransposon silencing by DNA methylation-dependent heterochromatin formation' SubClassOf 'retrotransposon silencing by heterochromatin formation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141090</classIRI>
<classLabel>protein serine pyrophosphorylase activity</classLabel>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'has_participant' some http://purl.obolibrary.org/obo/CHEBI_149682</newAxiom>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'has_participant' some 'O-phospho-L-serine(2-) residue'</newAxiom>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'has_participant' some '5-diphospho-1D-myo-inositol pentakisphosphate(13-)'</newAxiom>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'phosphotransferase activity, phosphate group as acceptor'</newAxiom>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'has_participant' some 'myo-inositol hexakisphosphate(12-)'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141094</classIRI>
<classLabel>DNA loop anchor binding</classLabel>
<newAxiom>'DNA loop anchor binding' SubClassOf 'sequence-specific DNA binding'</newAxiom>
<newAxiom>'DNA loop anchor binding' EquivalentTo 'sequence-specific DNA binding' and ('has input' some 'DNA_loop_anchor')</newAxiom>
<newAxiom>'DNA loop anchor binding' SubClassOf 'has input' some 'DNA_loop_anchor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141093</classIRI>
<classLabel>5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity</classLabel>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some 'L-tyrosine zwitterion'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some 'S-adenosyl-L-methionine zwitterion'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some 'dehydroglycine zwitterion'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some http://purl.obolibrary.org/obo/CHEBI_85936</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'transferase activity, transferring alkyl or aryl (other than methyl) groups'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some '5'-deoxyadenosine'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some '5-amino-6-(D-ribitylamino)uracil'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some 'hydron'</newAxiom>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'has_participant' some 'L-methionine zwitterion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141092</classIRI>
<classLabel>positive regulation of nodal signaling pathway</classLabel>
<newAxiom>'positive regulation of nodal signaling pathway' EquivalentTo 'biological regulation' and ('positively regulates' some 'nodal signaling pathway')</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf 'regulation of nodal signaling pathway'</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf 'positively regulates' some 'nodal signaling pathway'</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf 'positive regulation of activin receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141091</classIRI>
<classLabel>transforming growth factor beta receptor superfamily signaling pathway</classLabel>
<newAxiom>'transforming growth factor beta receptor superfamily signaling pathway' SubClassOf 'transmembrane receptor protein serine/threonine kinase signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_7500103</classIRI>
<classLabel>preorbital fossa</classLabel>
<newAxiom>'preorbital fossa' EquivalentTo 'bone fossa' and ('part_of' some 'preorbital bone region')</newAxiom>
<newAxiom>'preorbital fossa' SubClassOf 'bone fossa'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/UBERON_7500102</classIRI>
<classLabel>preorbital bone region</classLabel>
<newAxiom>'preorbital bone region' SubClassOf 'anatomical entity'</newAxiom>
<newAxiom>'preorbital bone region' SubClassOf 'part_of' some 'orbit of skull'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/CARO_0001010</classIRI>
</deletedClass>
<deletedClass>
<classIRI>http://www.geneontology.org/formats/oboInOwl#Subset</classIRI>
</deletedClass>
</deletedClasses>
</diffReport>