<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
177
</numberChangedClasses>
<numberNewClasses>
90
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051583</classIRI>
<classLabel>dopamine uptake involved in synaptic transmission</classLabel>
<newAxiom>&apos;dopamine uptake involved in synaptic transmission&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005218</classIRI>
<classLabel>intracellular ligand-gated calcium channel activity</classLabel>
<newAxiom>&apos;intracellular ligand-gated calcium channel activity&apos; SubClassOf &apos;receptor signaling protein activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005220</classIRI>
<classLabel>inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;intracellular ligand-gated ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;receptor signaling protein activity&apos;</deletedAxiom>
<deletedAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;calcium-release channel activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;intracellular ligand-gated calcium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051610</classIRI>
<classLabel>serotonin uptake</classLabel>
<deletedAxiom>&apos;serotonin uptake&apos; SubClassOf &apos;neurotransmitter uptake&apos;</deletedAxiom>
<newAxiom>&apos;serotonin uptake&apos; SubClassOf &apos;neurotransmitter reuptake&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051611</classIRI>
<classLabel>regulation of serotonin uptake</classLabel>
<newAxiom>&apos;regulation of serotonin uptake&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007340</classIRI>
<classLabel>acrosome reaction</classLabel>
<deletedAxiom>&apos;acrosome reaction&apos; SubClassOf &apos;single organism reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;acrosome reaction&apos; SubClassOf &apos;calcium ion-dependent exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;acrosome reaction&apos; SubClassOf &apos;reproductive process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042073</classIRI>
<classLabel>intraciliary transport</classLabel>
<deletedAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;microtubule-based transport&apos;</deletedAxiom>
<deletedAxiom>&apos;intraciliary transport&apos; EquivalentTo &apos;cytoskeleton-dependent intracellular transport&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;cilium&apos;)</deletedAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;protein complex localization&apos;</newAxiom>
<newAxiom>&apos;intraciliary transport&apos; SubClassOf &apos;protein transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034642</classIRI>
<classLabel>mitochondrion migration along actin filament</classLabel>
<newAxiom>&apos;mitochondrion migration along actin filament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099515</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048488</classIRI>
<classLabel>synaptic vesicle endocytosis</classLabel>
<deletedAxiom>&apos;synaptic vesicle endocytosis&apos; SubClassOf &apos;synaptic vesicle transport&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle endocytosis&apos; SubClassOf &apos;endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle endocytosis&apos; SubClassOf &apos;intracellular transport&apos;</newAxiom>
<newAxiom>&apos;synaptic vesicle endocytosis&apos; SubClassOf &apos;clathrin-mediated endocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048489</classIRI>
<classLabel>synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;synaptic vesicle transport&apos; SubClassOf &apos;single-organism transport&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle transport&apos; SubClassOf &apos;synaptic vesicle localization&apos;</newAxiom>
<newAxiom>&apos;synaptic vesicle transport&apos; SubClassOf &apos;single-organism intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903049</classIRI>
<classLabel>negative regulation of acetylcholine-gated cation channel activity</classLabel>
<newAxiom>&apos;negative regulation of acetylcholine-gated cation channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of acetylcholine-gated cation channel activity&apos; SubClassOf &apos;negative regulation of synaptic transmission&apos;</newAxiom>
<newAxiom>&apos;negative regulation of acetylcholine-gated cation channel activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903048</classIRI>
<classLabel>regulation of acetylcholine-gated cation channel activity</classLabel>
<newAxiom>&apos;regulation of acetylcholine-gated cation channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;regulation of acetylcholine-gated cation channel activity&apos; SubClassOf &apos;modulation of synaptic transmission&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048491</classIRI>
<classLabel>retrograde synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;retrograde synaptic vesicle transport&apos; SubClassOf &apos;synaptic vesicle transport&apos;</deletedAxiom>
<newAxiom>&apos;retrograde synaptic vesicle transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
<newAxiom>&apos;retrograde synaptic vesicle transport&apos; SubClassOf &apos;retrograde axon cargo transport&apos;</newAxiom>
<newAxiom>&apos;retrograde synaptic vesicle transport&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099517</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048490</classIRI>
<classLabel>anterograde synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;anterograde synaptic vesicle transport&apos; SubClassOf &apos;synaptic vesicle transport&apos;</deletedAxiom>
<newAxiom>&apos;anterograde synaptic vesicle transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
<newAxiom>&apos;anterograde synaptic vesicle transport&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099517</newAxiom>
<newAxiom>&apos;anterograde synaptic vesicle transport&apos; SubClassOf &apos;anterograde axon cargo transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051936</classIRI>
<classLabel>gamma-aminobutyric acid reuptake</classLabel>
<deletedAxiom>&apos;gamma-aminobutyric acid reuptake&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051935</classIRI>
<classLabel>glutamate reuptake</classLabel>
<deletedAxiom>&apos;glutamate reuptake&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051934</classIRI>
<classLabel>catecholamine uptake involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;catecholamine uptake involved in synaptic transmission&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051933</classIRI>
<classLabel>amino acid neurotransmitter reuptake</classLabel>
<deletedAxiom>&apos;amino acid neurotransmitter reuptake&apos; SubClassOf &apos;amino acid import&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid neurotransmitter reuptake&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;amino acid neurotransmitter reuptake&apos; SubClassOf &apos;amino acid import into cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051940</classIRI>
<classLabel>regulation of catecholamine uptake involved in synaptic transmission</classLabel>
<newAxiom>&apos;regulation of catecholamine uptake involved in synaptic transmission&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051941</classIRI>
<classLabel>regulation of amino acid uptake involved in synaptic transmission</classLabel>
<newAxiom>&apos;regulation of amino acid uptake involved in synaptic transmission&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036465</classIRI>
<classLabel>synaptic vesicle recycling</classLabel>
<newAxiom>&apos;synaptic vesicle recycling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099504</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048787</classIRI>
<classLabel>presynaptic active zone membrane</classLabel>
<deletedAxiom>&apos;presynaptic active zone membrane&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<deletedAxiom>&apos;presynaptic active zone membrane&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;presynaptic active zone membrane&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048788</classIRI>
<classLabel>cytoskeleton of presynaptic active zone</classLabel>
<deletedAxiom>&apos;cytoskeleton of presynaptic active zone&apos; SubClassOf &apos;neuron part&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoskeleton of presynaptic active zone&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;cytoskeleton of presynaptic active zone&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099569</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048792</classIRI>
<classLabel>calcium ion-independent exocytosis of neurotransmitter</classLabel>
<newAxiom>&apos;calcium ion-independent exocytosis of neurotransmitter&apos; SubClassOf &apos;synaptic vesicle exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048790</classIRI>
<classLabel>maintenance of presynaptic active zone structure</classLabel>
<deletedAxiom>&apos;maintenance of presynaptic active zone structure&apos; SubClassOf &apos;cellular component maintenance&apos;</deletedAxiom>
<newAxiom>&apos;maintenance of presynaptic active zone structure&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099558</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048791</classIRI>
<classLabel>calcium ion-dependent exocytosis of neurotransmitter</classLabel>
<deletedAxiom>&apos;calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;neurotransmitter secretion&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;synaptic vesicle exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042734</classIRI>
<classLabel>presynaptic membrane</classLabel>
<newAxiom>&apos;presynaptic membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;presynapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019896</classIRI>
<classLabel>axon transport of mitochondrion</classLabel>
<newAxiom>&apos;axon transport of mitochondrion&apos; SubClassOf &apos;mitochondrion transport along microtubule&apos;</newAxiom>
<newAxiom>&apos;axon transport of mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005938</classIRI>
<classLabel>cell cortex</classLabel>
<deletedAxiom>&apos;cell cortex&apos; SubClassOf &apos;cytoplasmic part&apos;</deletedAxiom>
<newAxiom>&apos;cell cortex&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099568</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005874</classIRI>
<classLabel>microtubule</classLabel>
<deletedAxiom>&apos;microtubule&apos; SubClassOf &apos;protein complex&apos;</deletedAxiom>
<newAxiom>&apos;microtubule&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005882</classIRI>
<classLabel>intermediate filament</classLabel>
<deletedAxiom>&apos;intermediate filament&apos; SubClassOf &apos;protein complex&apos;</deletedAxiom>
<newAxiom>&apos;intermediate filament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005884</classIRI>
<classLabel>actin filament</classLabel>
<deletedAxiom>&apos;actin filament&apos; SubClassOf &apos;protein complex&apos;</deletedAxiom>
<newAxiom>&apos;actin filament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099513</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036062</classIRI>
<classLabel>presynaptic periactive zone</classLabel>
<deletedAxiom>&apos;presynaptic periactive zone&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;presynaptic periactive zone&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<newAxiom>&apos;presynaptic periactive zone&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016907</classIRI>
<classLabel>G-protein coupled acetylcholine receptor activity</classLabel>
<newAxiom>&apos;G-protein coupled acetylcholine receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099528</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031585</classIRI>
<classLabel>regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031586</classIRI>
<classLabel>negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031587</classIRI>
<classLabel>positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902803</classIRI>
<classLabel>regulation of synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;regulation of synaptic vesicle transport&apos; SubClassOf &apos;regulation of cellular localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of synaptic vesicle transport&apos; SubClassOf &apos;modulation of synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;regulation of synaptic vesicle transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902805</classIRI>
<classLabel>positive regulation of synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;positive regulation of synaptic vesicle transport&apos; SubClassOf &apos;positive regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of synaptic vesicle transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902804</classIRI>
<classLabel>negative regulation of synaptic vesicle transport</classLabel>
<deletedAxiom>&apos;negative regulation of synaptic vesicle transport&apos; SubClassOf &apos;negative regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of synaptic vesicle transport&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098700</classIRI>
<classLabel>neurotransmitter loading into synaptic vesicle</classLabel>
<newAxiom>&apos;neurotransmitter loading into synaptic vesicle&apos; SubClassOf &apos;establishment of localization in cell&apos;</newAxiom>
<newAxiom>&apos;neurotransmitter loading into synaptic vesicle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099504</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902937</classIRI>
<classLabel>inward rectifier potassium channel complex</classLabel>
<newAxiom>&apos;inward rectifier potassium channel complex&apos; SubClassOf &apos;plasma membrane receptor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098828</classIRI>
<classLabel>modulation of inihbitory postsynaptic potential</classLabel>
<newAxiom>&apos;modulation of inihbitory postsynaptic potential&apos; SubClassOf &apos;regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098839</classIRI>
<classLabel>postsynaptic density membrane</classLabel>
<deletedAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic density membrane&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098835</classIRI>
<classLabel>presynaptic endocytic zone membrane</classLabel>
<deletedAxiom>&apos;presynaptic endocytic zone membrane&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<deletedAxiom>&apos;presynaptic endocytic zone membrane&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;presynaptic endocytic zone membrane&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098836</classIRI>
<classLabel>cytoskeleton of dendritic spine</classLabel>
<deletedAxiom>&apos;cytoskeleton of dendritic spine&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoskeleton of dendritic spine&apos; SubClassOf &apos;cytoskeleton&apos;</deletedAxiom>
<newAxiom>&apos;cytoskeleton of dendritic spine&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099571</newAxiom>
<newAxiom>&apos;cytoskeleton of dendritic spine&apos; EquivalentTo &apos;cytoskeleton&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;dendritic spine&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098810</classIRI>
<classLabel>neurotransmitter reuptake</classLabel>
<deletedAxiom>&apos;neurotransmitter reuptake&apos; EquivalentTo &apos;neurotransmitter uptake&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;)</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter reuptake&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;neurotransmitter reuptake&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;presynapse&apos;</newAxiom>
<newAxiom>&apos;neurotransmitter reuptake&apos; SubClassOf &apos;establishment of localization in cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098815</classIRI>
<classLabel>modulation of excitatory postsynaptic potential</classLabel>
<newAxiom>&apos;modulation of excitatory postsynaptic potential&apos; SubClassOf &apos;regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098844</classIRI>
<classLabel>postsynaptic endocytic zone membrane</classLabel>
<deletedAxiom>&apos;postsynaptic endocytic zone membrane&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic endocytic zone membrane&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic endocytic zone membrane&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098866</classIRI>
<classLabel>multivesicular body fusion to apical plasma membrane</classLabel>
<newAxiom>&apos;multivesicular body fusion to apical plasma membrane&apos; SubClassOf &apos;plasma membrane fusion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031629</classIRI>
<classLabel>synaptic vesicle fusion to presynaptic membrane</classLabel>
<deletedAxiom>&apos;synaptic vesicle fusion to presynaptic membrane&apos; SubClassOf &apos;vesicle fusion&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle fusion to presynaptic membrane&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099500</newAxiom>
<newAxiom>&apos;synaptic vesicle fusion to presynaptic membrane&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904602</classIRI>
<classLabel>serotonin-activated cation-selective channel complex</classLabel>
<newAxiom>&apos;serotonin-activated cation-selective channel complex&apos; SubClassOf &apos;receptor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031022</classIRI>
<classLabel>nuclear migration along microfilament</classLabel>
<newAxiom>&apos;nuclear migration along microfilament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099515</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900244</classIRI>
<classLabel>positive regulation of synaptic vesicle endocytosis</classLabel>
<deletedAxiom>&apos;positive regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;positive regulation of endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;positive regulation of clathrin-mediated endocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900242</classIRI>
<classLabel>regulation of synaptic vesicle endocytosis</classLabel>
<deletedAxiom>&apos;regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;regulation of endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;regulation of clathrin-mediated endocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900243</classIRI>
<classLabel>negative regulation of synaptic vesicle endocytosis</classLabel>
<deletedAxiom>&apos;negative regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;negative regulation of endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of synaptic vesicle endocytosis&apos; SubClassOf &apos;negative regulation of clathrin-mediated endocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904810</classIRI>
<classLabel>negative regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;negative regulation of dense core granule transport&apos; SubClassOf &apos;negative regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of dense core granule transport&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904811</classIRI>
<classLabel>positive regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;positive regulation of dense core granule transport&apos; SubClassOf &apos;positive regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of dense core granule transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904809</classIRI>
<classLabel>regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;regulation of dense core granule transport&apos; SubClassOf &apos;regulation of transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dense core granule transport&apos; SubClassOf &apos;regulation of cellular localization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of dense core granule transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014069</classIRI>
<classLabel>postsynaptic density</classLabel>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;postsynapse&apos;</deletedAxiom>
<deletedAxiom>&apos;postsynaptic density&apos; SubClassOf &apos;cell part&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic density&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;excitatory synapse&apos;</newAxiom>
<newAxiom>&apos;postsynaptic density&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099572</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016320</classIRI>
<classLabel>endoplasmic reticulum membrane fusion</classLabel>
<deletedAxiom>&apos;endoplasmic reticulum membrane fusion&apos; SubClassOf &apos;organelle fusion&apos;</deletedAxiom>
<deletedAxiom>&apos;endoplasmic reticulum membrane fusion&apos; SubClassOf &apos;single-organism organelle organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008090</classIRI>
<classLabel>retrograde axon cargo transport</classLabel>
<newAxiom>&apos;retrograde axon cargo transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016079</classIRI>
<classLabel>synaptic vesicle exocytosis</classLabel>
<deletedAxiom>&apos;synaptic vesicle exocytosis&apos; SubClassOf &apos;exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle exocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099504</newAxiom>
<newAxiom>&apos;synaptic vesicle exocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
<newAxiom>&apos;synaptic vesicle exocytosis&apos; SubClassOf &apos;calcium ion-dependent exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016082</classIRI>
<classLabel>synaptic vesicle priming</classLabel>
<newAxiom>&apos;synaptic vesicle priming&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016081</classIRI>
<classLabel>synaptic vesicle docking</classLabel>
<newAxiom>&apos;synaptic vesicle docking&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
<newAxiom>&apos;synaptic vesicle docking&apos; EquivalentTo &apos;vesicle docking&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic vesicle exocytosis&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016080</classIRI>
<classLabel>synaptic vesicle targeting</classLabel>
<newAxiom>&apos;synaptic vesicle targeting&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099531</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008021</classIRI>
<classLabel>synaptic vesicle</classLabel>
<deletedAxiom>&apos;synaptic vesicle&apos; SubClassOf &apos;cytoplasmic membrane-bounded vesicle&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle&apos; SubClassOf &apos;exocytic vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008088</classIRI>
<classLabel>axon cargo transport</classLabel>
<newAxiom>&apos;axon cargo transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;neuron projection&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008089</classIRI>
<classLabel>anterograde axon cargo transport</classLabel>
<newAxiom>&apos;anterograde axon cargo transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043197</classIRI>
<classLabel>dendritic spine</classLabel>
<deletedAxiom>&apos;dendritic spine&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;dendritic spine&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;postsynapse&apos;</deletedAxiom>
<newAxiom>&apos;dendritic spine&apos; SubClassOf &apos;postsynapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043195</classIRI>
<classLabel>terminal bouton</classLabel>
<deletedAxiom>&apos;terminal bouton&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;terminal bouton&apos; SubClassOf &apos;presynapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016182</classIRI>
<classLabel>synaptic vesicle budding from endosome</classLabel>
<deletedAxiom>&apos;synaptic vesicle budding from endosome&apos; EquivalentTo &apos;synaptic vesicle budding&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic vesicle exocytosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle budding from endosome&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic vesicle exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle budding from endosome&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099532</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016189</classIRI>
<classLabel>synaptic vesicle to endosome fusion</classLabel>
<deletedAxiom>&apos;synaptic vesicle to endosome fusion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic vesicle recycling via endosome&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle to endosome fusion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099532</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008188</classIRI>
<classLabel>neuropeptide receptor activity</classLabel>
<deletedAxiom>&apos;neuropeptide receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022850</classIRI>
<classLabel>serotonin-gated cation channel activity</classLabel>
<newAxiom>&apos;serotonin-gated cation channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099589</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022851</classIRI>
<classLabel>GABA-gated chloride ion channel activity</classLabel>
<newAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf &apos;chloride channel activity&apos;</newAxiom>
<newAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf &apos;GABA receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022852</classIRI>
<classLabel>glycine-gated chloride ion channel activity</classLabel>
<newAxiom>&apos;glycine-gated chloride ion channel activity&apos; SubClassOf &apos;chloride channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022849</classIRI>
<classLabel>glutamate-gated calcium ion channel activity</classLabel>
<newAxiom>&apos;glutamate-gated calcium ion channel activity&apos; SubClassOf &apos;calcium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022848</classIRI>
<classLabel>acetylcholine-gated cation channel activity</classLabel>
<newAxiom>&apos;acetylcholine-gated cation channel activity&apos; SubClassOf &apos;acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022835</classIRI>
<classLabel>transmitter-gated channel activity</classLabel>
<newAxiom>&apos;transmitter-gated channel activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022834</classIRI>
<classLabel>ligand-gated channel activity</classLabel>
<newAxiom>&apos;ligand-gated channel activity&apos; SubClassOf &apos;receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902159</classIRI>
<classLabel>regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<newAxiom>&apos;regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902161</classIRI>
<classLabel>positive regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<newAxiom>&apos;positive regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;positive regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902160</classIRI>
<classLabel>negative regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<newAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990474</classIRI>
<classLabel>synaptic vesicle, readily releasable pool</classLabel>
<deletedAxiom>&apos;synaptic vesicle, readily releasable pool&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle, readily releasable pool&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;synaptic vesicle&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle, readily releasable pool&apos; SubClassOf &apos;synaptic vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990475</classIRI>
<classLabel>synaptic vesicle, recycling pool</classLabel>
<deletedAxiom>&apos;synaptic vesicle, recycling pool&apos; SubClassOf &apos;axon part&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle, recycling pool&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;terminal bouton&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle, recycling pool&apos; SubClassOf &apos;cell part&apos;</newAxiom>
<newAxiom>&apos;synaptic vesicle, recycling pool&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;postsynapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990476</classIRI>
<classLabel>synaptic vesicle, resting pool</classLabel>
<deletedAxiom>&apos;synaptic vesicle, resting pool&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;synaptic vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle, resting pool&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle, resting pool&apos; SubClassOf &apos;synaptic vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051279</classIRI>
<classLabel>regulation of release of sequestered calcium ion into cytosol</classLabel>
<newAxiom>&apos;regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;regulation of calcium ion import&apos;</newAxiom>
<newAxiom>&apos;regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;regulation of calcium ion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051280</classIRI>
<classLabel>negative regulation of release of sequestered calcium ion into cytosol</classLabel>
<newAxiom>&apos;negative regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;negative regulation of calcium ion import&apos;</newAxiom>
<newAxiom>&apos;negative regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;negative regulation of calcium ion transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051281</classIRI>
<classLabel>positive regulation of release of sequestered calcium ion into cytosol</classLabel>
<newAxiom>&apos;positive regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;positive regulation of release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;positive regulation of calcium ion import&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051209</classIRI>
<classLabel>release of sequestered calcium ion into cytosol</classLabel>
<deletedAxiom>&apos;release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;calcium ion transport into cytosol&apos;</deletedAxiom>
<deletedAxiom>&apos;release of sequestered calcium ion into cytosol&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;sequestering of calcium ion&apos;</deletedAxiom>
<deletedAxiom>&apos;release of sequestered calcium ion into cytosol&apos; EquivalentTo &apos;calcium ion transport into cytosol&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;sequestering of calcium ion&apos;)</deletedAxiom>
<newAxiom>&apos;release of sequestered calcium ion into cytosol&apos; SubClassOf &apos;calcium ion transmembrane import into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031887</classIRI>
<classLabel>lipid particle transport along microtubule</classLabel>
<deletedAxiom>&apos;lipid particle transport along microtubule&apos; SubClassOf &apos;microtubule-based transport&apos;</deletedAxiom>
<deletedAxiom>&apos;lipid particle transport along microtubule&apos; SubClassOf &apos;single-organism cellular localization&apos;</deletedAxiom>
<deletedAxiom>&apos;lipid particle transport along microtubule&apos; SubClassOf &apos;organelle localization&apos;</deletedAxiom>
<newAxiom>&apos;lipid particle transport along microtubule&apos; SubClassOf &apos;organelle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001504</classIRI>
<classLabel>neurotransmitter uptake</classLabel>
<newAxiom>&apos;neurotransmitter uptake&apos; SubClassOf &apos;import into cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000300</classIRI>
<classLabel>regulation of synaptic vesicle exocytosis</classLabel>
<deletedAxiom>&apos;regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;regulation of calcium ion-dependent exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000302</classIRI>
<classLabel>positive regulation of synaptic vesicle exocytosis</classLabel>
<deletedAxiom>&apos;positive regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;positive regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;positive regulation of calcium ion-dependent exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000301</classIRI>
<classLabel>negative regulation of synaptic vesicle exocytosis</classLabel>
<deletedAxiom>&apos;negative regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;negative regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of synaptic vesicle exocytosis&apos; SubClassOf &apos;negative regulation of calcium ion-dependent exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045955</classIRI>
<classLabel>negative regulation of calcium ion-dependent exocytosis</classLabel>
<deletedAxiom>&apos;negative regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;negative regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;negative regulation of regulated secretory pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045956</classIRI>
<classLabel>positive regulation of calcium ion-dependent exocytosis</classLabel>
<deletedAxiom>&apos;positive regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;positive regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;positive regulation of regulated secretory pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000463</classIRI>
<classLabel>positive regulation of excitatory postsynaptic potential</classLabel>
<newAxiom>&apos;positive regulation of excitatory postsynaptic potential&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902656</classIRI>
<classLabel>calcium ion import into cytosol</classLabel>
<deletedAxiom>&apos;calcium ion import into cytosol&apos; SubClassOf &apos;single-organism intracellular transport&apos;</deletedAxiom>
<deletedAxiom>&apos;calcium ion import into cytosol&apos; SubClassOf &apos;cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion import into cytosol&apos; SubClassOf &apos;calcium ion transport into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050804</classIRI>
<classLabel>modulation of synaptic transmission</classLabel>
<deletedAxiom>&apos;modulation of synaptic transmission&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;modulation of synaptic transmission&apos; EquivalentTo &apos;biological_process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;synaptic transmission&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904315</classIRI>
<classLabel>transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>&apos;transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099529</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904115</classIRI>
<classLabel>axon cytoplasm</classLabel>
<deletedAxiom>&apos;axon cytoplasm&apos; SubClassOf &apos;cytoplasm&apos;</deletedAxiom>
<newAxiom>&apos;axon cytoplasm&apos; SubClassOf &apos;cell projection cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047496</classIRI>
<classLabel>vesicle transport along microtubule</classLabel>
<deletedAxiom>&apos;vesicle transport along microtubule&apos; SubClassOf &apos;establishment of vesicle localization&apos;</deletedAxiom>
<deletedAxiom>&apos;vesicle transport along microtubule&apos; SubClassOf &apos;single-organism cellular localization&apos;</deletedAxiom>
<newAxiom>&apos;vesicle transport along microtubule&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099518</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990049</classIRI>
<classLabel>retrograde dense core granule transport</classLabel>
<deletedAxiom>&apos;retrograde dense core granule transport&apos; SubClassOf &apos;dense core granule transport&apos;</deletedAxiom>
<newAxiom>&apos;retrograde dense core granule transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
<newAxiom>&apos;retrograde dense core granule transport&apos; SubClassOf &apos;retrograde axon cargo transport&apos;</newAxiom>
<newAxiom>&apos;retrograde dense core granule transport&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099519</newAxiom>
<newAxiom>&apos;retrograde dense core granule transport&apos; SubClassOf &apos;vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990048</classIRI>
<classLabel>anterograde dense core granule transport</classLabel>
<deletedAxiom>&apos;anterograde dense core granule transport&apos; SubClassOf &apos;dense core granule transport&apos;</deletedAxiom>
<newAxiom>&apos;anterograde dense core granule transport&apos; SubClassOf &apos;vesicle transport along microtubule&apos;</newAxiom>
<newAxiom>&apos;anterograde dense core granule transport&apos; SubClassOf &apos;anterograde axon cargo transport&apos;</newAxiom>
<newAxiom>&apos;anterograde dense core granule transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;axon&apos;</newAxiom>
<newAxiom>&apos;anterograde dense core granule transport&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099519</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090394</classIRI>
<classLabel>negative regulation of excitatory postsynaptic potential</classLabel>
<newAxiom>&apos;negative regulation of excitatory postsynaptic potential&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070509</classIRI>
<classLabel>calcium ion import</classLabel>
<deletedAxiom>&apos;calcium ion import&apos; SubClassOf &apos;metal ion transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion import&apos; SubClassOf &apos;calcium ion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090118</classIRI>
<classLabel>receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport</classLabel>
<deletedAxiom>&apos;receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
<deletedAxiom>&apos;receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport&apos; SubClassOf &apos;single-organism transport&apos;</deletedAxiom>
<newAxiom>&apos;receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport&apos; SubClassOf &apos;single-organism intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090110</classIRI>
<classLabel>cargo loading into COPII-coated vesicle</classLabel>
<deletedAxiom>&apos;cargo loading into COPII-coated vesicle&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
<newAxiom>&apos;cargo loading into COPII-coated vesicle&apos; SubClassOf &apos;single-organism intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090174</classIRI>
<classLabel>organelle membrane fusion</classLabel>
<newAxiom>&apos;organelle membrane fusion&apos; SubClassOf &apos;organelle fusion&apos;</newAxiom>
<newAxiom>&apos;organelle membrane fusion&apos; SubClassOf &apos;single-organism organelle organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006906</classIRI>
<classLabel>vesicle fusion</classLabel>
<deletedAxiom>&apos;vesicle fusion&apos; SubClassOf &apos;single-organism organelle organization&apos;</deletedAxiom>
<deletedAxiom>&apos;vesicle fusion&apos; SubClassOf &apos;organelle fusion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015842</classIRI>
<classLabel>synaptic vesicle amine transport</classLabel>
<deletedAxiom>&apos;synaptic vesicle amine transport&apos; SubClassOf &apos;synaptic vesicle transport&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle amine transport&apos; SubClassOf &apos;neurotransmitter loading into synaptic vesicle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006886</classIRI>
<classLabel>intracellular protein transport</classLabel>
<deletedAxiom>&apos;intracellular protein transport&apos; EquivalentTo &apos;protein transport&apos; and &apos;intracellular transport&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;intracellular&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006897</classIRI>
<classLabel>endocytosis</classLabel>
<newAxiom>&apos;endocytosis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;membrane budding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070382</classIRI>
<classLabel>exocytic vesicle</classLabel>
<newAxiom>&apos;exocytic vesicle&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099503</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072578</classIRI>
<classLabel>neurotransmitter-gated ion channel clustering</classLabel>
<deletedAxiom>&apos;neurotransmitter-gated ion channel clustering&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synapse assembly&apos;</deletedAxiom>
<newAxiom>&apos;neurotransmitter-gated ion channel clustering&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synapse organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072384</classIRI>
<classLabel>organelle transport along microtubule</classLabel>
<newAxiom>&apos;organelle transport along microtubule&apos; SubClassOf &apos;single-organism cellular localization&apos;</newAxiom>
<newAxiom>&apos;organelle transport along microtubule&apos; SubClassOf &apos;organelle localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004993</classIRI>
<classLabel>serotonin receptor activity</classLabel>
<newAxiom>&apos;serotonin receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099589</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004952</classIRI>
<classLabel>dopamine neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;dopamine neurotransmitter receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;dopamine neurotransmitter receptor activity&apos; SubClassOf &apos;G-protein coupled receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;dopamine neurotransmitter receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099528</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030050</classIRI>
<classLabel>vesicle transport along actin filament</classLabel>
<deletedAxiom>&apos;vesicle transport along actin filament&apos; SubClassOf &apos;single-organism transport&apos;</deletedAxiom>
<deletedAxiom>&apos;vesicle transport along actin filament&apos; SubClassOf &apos;single-organism cellular localization&apos;</deletedAxiom>
<deletedAxiom>&apos;vesicle transport along actin filament&apos; SubClassOf &apos;establishment of vesicle localization&apos;</deletedAxiom>
<newAxiom>&apos;vesicle transport along actin filament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099518</newAxiom>
<newAxiom>&apos;vesicle transport along actin filament&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099515</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097401</classIRI>
<classLabel>synaptic vesicle lumen acidification</classLabel>
<newAxiom>&apos;synaptic vesicle lumen acidification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099504</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060316</classIRI>
<classLabel>positive regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
<newAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of intracellular signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060315</classIRI>
<classLabel>negative regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;negative regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
<newAxiom>&apos;negative regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of intracellular signal transduction&apos;</newAxiom>
<newAxiom>&apos;negative regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060314</classIRI>
<classLabel>regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<newAxiom>&apos;regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</newAxiom>
<newAxiom>&apos;regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of release of sequestered calcium ion into cytosol&apos;</newAxiom>
<newAxiom>&apos;regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097553</classIRI>
<classLabel>calcium ion transmembrane import into cytosol</classLabel>
<deletedAxiom>&apos;calcium ion transmembrane import into cytosol&apos; SubClassOf &apos;calcium ion transport into cytosol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032838</classIRI>
<classLabel>cell projection cytoplasm</classLabel>
<deletedAxiom>&apos;cell projection cytoplasm&apos; SubClassOf &apos;cytoplasmic part&apos;</deletedAxiom>
<newAxiom>&apos;cell projection cytoplasm&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099568</newAxiom>
<newAxiom>&apos;cell projection cytoplasm&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell projection&apos;</newAxiom>
<newAxiom>&apos;cell projection cytoplasm&apos; EquivalentTo &apos;cytoplasm&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell projection&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019183</classIRI>
<classLabel>histamine-gated chloride channel complex</classLabel>
<deletedAxiom>&apos;histamine-gated chloride channel complex&apos; SubClassOf &apos;plasma membrane protein complex&apos;</deletedAxiom>
<newAxiom>&apos;histamine-gated chloride channel complex&apos; SubClassOf &apos;plasma membrane receptor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated ion channel activity</classLabel>
<newAxiom>&apos;ligand-gated ion channel activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015279</classIRI>
<classLabel>store-operated calcium channel activity</classLabel>
<deletedAxiom>&apos;store-operated calcium channel activity&apos; SubClassOf &apos;ligand-gated ion channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015278</classIRI>
<classLabel>calcium-release channel activity</classLabel>
<deletedAxiom>&apos;calcium-release channel activity&apos; SubClassOf &apos;ligand-gated ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;calcium-release channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;release of sequestered calcium ion into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901980</classIRI>
<classLabel>positive regulation of inward rectifier potassium channel activity</classLabel>
<newAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
<newAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901979</classIRI>
<classLabel>regulation of inward rectifier potassium channel activity</classLabel>
<newAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901954</classIRI>
<classLabel>regulation of retrograde dense core granule transport</classLabel>
<newAxiom>&apos;regulation of retrograde dense core granule transport&apos; SubClassOf &apos;regulation of retrograde axon cargo transport&apos;</newAxiom>
<newAxiom>&apos;regulation of retrograde dense core granule transport&apos; SubClassOf &apos;regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901953</classIRI>
<classLabel>positive regulation of anterograde dense core granule transport</classLabel>
<newAxiom>&apos;positive regulation of anterograde dense core granule transport&apos; SubClassOf &apos;positive regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901956</classIRI>
<classLabel>positive regulation of retrograde dense core granule transport</classLabel>
<newAxiom>&apos;positive regulation of retrograde dense core granule transport&apos; SubClassOf &apos;positive regulation of vesicle transport along microtubule&apos;</newAxiom>
<newAxiom>&apos;positive regulation of retrograde dense core granule transport&apos; SubClassOf &apos;positive regulation of retrograde axon cargo transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901955</classIRI>
<classLabel>negative regulation of retrograde dense core granule transport</classLabel>
<newAxiom>&apos;negative regulation of retrograde dense core granule transport&apos; SubClassOf &apos;negative regulation of vesicle transport along microtubule&apos;</newAxiom>
<newAxiom>&apos;negative regulation of retrograde dense core granule transport&apos; SubClassOf &apos;negative regulation of retrograde axon cargo transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901950</classIRI>
<classLabel>dense core granule transport</classLabel>
<deletedAxiom>&apos;dense core granule transport&apos; SubClassOf &apos;transport&apos;</deletedAxiom>
<newAxiom>&apos;dense core granule transport&apos; SubClassOf &apos;intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901952</classIRI>
<classLabel>negative regulation of anterograde dense core granule transport</classLabel>
<newAxiom>&apos;negative regulation of anterograde dense core granule transport&apos; SubClassOf &apos;negative regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901951</classIRI>
<classLabel>regulation of anterograde dense core granule transport</classLabel>
<newAxiom>&apos;regulation of anterograde dense core granule transport&apos; SubClassOf &apos;regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015301</classIRI>
<classLabel>anion:anion antiporter activity</classLabel>
<deletedAxiom>&apos;anion:anion antiporter activity&apos; SubClassOf &apos;antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;anion:anion antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099516</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060079</classIRI>
<classLabel>excitatory postsynaptic potential</classLabel>
<newAxiom>&apos;excitatory postsynaptic potential&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099565</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060078</classIRI>
<classLabel>regulation of postsynaptic membrane potential</classLabel>
<deletedAxiom>&apos;regulation of postsynaptic membrane potential&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060080</classIRI>
<classLabel>inhibitory postsynaptic potential</classLabel>
<newAxiom>&apos;inhibitory postsynaptic potential&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099565</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097352</classIRI>
<classLabel>autophagosome maturation</classLabel>
<deletedAxiom>&apos;autophagosome maturation&apos; SubClassOf &apos;single-organism organelle organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030473</classIRI>
<classLabel>nuclear migration along microtubule</classLabel>
<deletedAxiom>&apos;nuclear migration along microtubule&apos; SubClassOf &apos;single-organism cellular localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000740</classIRI>
<classLabel>nuclear membrane fusion</classLabel>
<newAxiom>&apos;nuclear membrane fusion&apos; SubClassOf &apos;karyogamy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901660</classIRI>
<classLabel>calcium ion export</classLabel>
<deletedAxiom>&apos;calcium ion export&apos; SubClassOf &apos;metal ion transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion export&apos; SubClassOf &apos;calcium ion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097060</classIRI>
<classLabel>synaptic membrane</classLabel>
<newAxiom>&apos;synaptic membrane&apos; EquivalentTo &apos;plasma membrane region&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synapse&apos;)</newAxiom>
<newAxiom>&apos;synaptic membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synapse&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097014</classIRI>
<classLabel>ciliary cytoplasm</classLabel>
<deletedAxiom>&apos;ciliary cytoplasm&apos; SubClassOf &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015491</classIRI>
<classLabel>cation:cation antiporter activity</classLabel>
<newAxiom>&apos;cation:cation antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099516</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032591</classIRI>
<classLabel>dendritic spine membrane</classLabel>
<deletedAxiom>&apos;dendritic spine membrane&apos; SubClassOf &apos;synapse part&apos;</deletedAxiom>
<newAxiom>&apos;dendritic spine membrane&apos; SubClassOf &apos;synaptic membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097107</classIRI>
<classLabel>postsynaptic density assembly</classLabel>
<deletedAxiom>&apos;postsynaptic density assembly&apos; SubClassOf &apos;cellular component assembly&apos;</deletedAxiom>
<newAxiom>&apos;postsynaptic density assembly&apos; SubClassOf &apos;organelle assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097151</classIRI>
<classLabel>positive regulation of inhibitory postsynaptic potential</classLabel>
<newAxiom>&apos;positive regulation of inhibitory postsynaptic potential&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030141</classIRI>
<classLabel>secretory granule</classLabel>
<deletedAxiom>&apos;secretory granule&apos; SubClassOf &apos;cytoplasmic membrane-bounded vesicle&apos;</deletedAxiom>
<newAxiom>&apos;secretory granule&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099503</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901586</classIRI>
<classLabel>negative regulation of acid-sensing ion channel activity</classLabel>
<newAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901587</classIRI>
<classLabel>positive regulation of acid-sensing ion channel activity</classLabel>
<newAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901585</classIRI>
<classLabel>regulation of acid-sensing ion channel activity</classLabel>
<newAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901546</classIRI>
<classLabel>regulation of synaptic vesicle lumen acidification</classLabel>
<deletedAxiom>&apos;regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;regulation of synaptic vesicle endocytosis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;regulation of transport&apos;</newAxiom>
<newAxiom>&apos;regulation of synaptic vesicle lumen acidification&apos; SubClassOf &apos;regulation of cellular localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017156</classIRI>
<classLabel>calcium ion-dependent exocytosis</classLabel>
<deletedAxiom>&apos;calcium ion-dependent exocytosis&apos; SubClassOf &apos;exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion-dependent exocytosis&apos; SubClassOf &apos;regulated secretory pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017158</classIRI>
<classLabel>regulation of calcium ion-dependent exocytosis</classLabel>
<deletedAxiom>&apos;regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;regulation of exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of calcium ion-dependent exocytosis&apos; SubClassOf &apos;regulation of regulated secretory pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002552</classIRI>
<classLabel>serotonin secretion by mast cell</classLabel>
<newAxiom>&apos;serotonin secretion by mast cell&apos; SubClassOf &apos;single-organism intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002553</classIRI>
<classLabel>histamine secretion by mast cell</classLabel>
<newAxiom>&apos;histamine secretion by mast cell&apos; SubClassOf &apos;single-organism intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903515</classIRI>
<classLabel>calcium ion transport from cytosol to endoplasmic reticulum</classLabel>
<deletedAxiom>&apos;calcium ion transport from cytosol to endoplasmic reticulum&apos; SubClassOf &apos;metal ion transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion transport from cytosol to endoplasmic reticulum&apos; SubClassOf &apos;cytosolic calcium ion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903514</classIRI>
<classLabel>calcium ion transport from endoplasmic reticulum to cytosol</classLabel>
<deletedAxiom>&apos;calcium ion transport from endoplasmic reticulum to cytosol&apos; SubClassOf &apos;metal ion transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion transport from endoplasmic reticulum to cytosol&apos; SubClassOf &apos;calcium ion transport into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030672</classIRI>
<classLabel>synaptic vesicle membrane</classLabel>
<deletedAxiom>&apos;synaptic vesicle membrane&apos; SubClassOf &apos;bounding membrane of organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;synaptic vesicle membrane&apos; SubClassOf &apos;cytoplasmic vesicle part&apos;</deletedAxiom>
<newAxiom>&apos;synaptic vesicle membrane&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099501</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903235</classIRI>
<classLabel>positive regulation of calcium ion-dependent exocytosis of neurotransmitter</classLabel>
<deletedAxiom>&apos;positive regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;positive regulation of neurotransmitter secretion&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;positive regulation of synaptic vesicle exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903234</classIRI>
<classLabel>negative regulation of calcium ion-dependent exocytosis of neurotransmitter</classLabel>
<deletedAxiom>&apos;negative regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;negative regulation of neurotransmitter secretion&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;negative regulation of synaptic vesicle exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903233</classIRI>
<classLabel>regulation of calcium ion-dependent exocytosis of neurotransmitter</classLabel>
<deletedAxiom>&apos;regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;regulation of neurotransmitter secretion&apos;</deletedAxiom>
<newAxiom>&apos;regulation of calcium ion-dependent exocytosis of neurotransmitter&apos; SubClassOf &apos;regulation of synaptic vesicle exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030594</classIRI>
<classLabel>neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;postsynaptic membrane&apos;</newAxiom>
<newAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0099565</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903609</classIRI>
<classLabel>negative regulation of inward rectifier potassium channel activity</classLabel>
<newAxiom>&apos;negative regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;negative regulation of receptor activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;negative regulation of signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017071</classIRI>
<classLabel>intracellular cyclic nucleotide activated cation channel complex</classLabel>
<newAxiom>&apos;intracellular cyclic nucleotide activated cation channel complex&apos; SubClassOf &apos;receptor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007268</classIRI>
<classLabel>synaptic transmission</classLabel>
<deletedAxiom>&apos;synaptic transmission&apos; SubClassOf &apos;cell-cell signaling&apos;</deletedAxiom>
<newAxiom>&apos;synaptic transmission&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0099537</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903744</classIRI>
<classLabel>positive regulation of anterograde synaptic vesicle transport</classLabel>
<newAxiom>&apos;positive regulation of anterograde synaptic vesicle transport&apos; SubClassOf &apos;positive regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903742</classIRI>
<classLabel>regulation of anterograde synaptic vesicle transport</classLabel>
<newAxiom>&apos;regulation of anterograde synaptic vesicle transport&apos; SubClassOf &apos;regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903743</classIRI>
<classLabel>negative regulation of anterograde synaptic vesicle transport</classLabel>
<newAxiom>&apos;negative regulation of anterograde synaptic vesicle transport&apos; SubClassOf &apos;negative regulation of vesicle transport along microtubule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046907</classIRI>
<classLabel>intracellular transport</classLabel>
<newAxiom>&apos;intracellular transport&apos; EquivalentTo &apos;transport&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;intracellular&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099500</classIRI>
<classLabel>vesicle fusion to plasma membrane</classLabel>
<newAxiom>'vesicle fusion to plasma membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'exocytosis'</newAxiom>
<newAxiom>'vesicle fusion to plasma membrane' SubClassOf 'vesicle fusion'</newAxiom>
<newAxiom>'vesicle fusion to plasma membrane' SubClassOf 'plasma membrane fusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099510</classIRI>
<classLabel>calcium ion binding involved in regulation of cytosolic calcium ion concentration</classLabel>
<newAxiom>'calcium ion binding involved in regulation of cytosolic calcium ion concentration' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of cytosolic calcium ion concentration' SubClassOf 'calcium ion binding'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of cytosolic calcium ion concentration' EquivalentTo 'calcium ion binding' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of cytosolic calcium ion concentration')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099511</classIRI>
<classLabel>voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels</classLabel>
<newAxiom>'voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels' SubClassOf 'voltage-gated calcium channel activity'</newAxiom>
<newAxiom>'voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission'</newAxiom>
<newAxiom>'voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels' EquivalentTo 'voltage-gated calcium channel activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration')</newAxiom>
<newAxiom>'voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099509</classIRI>
<classLabel>regulation of presynaptic cytosolic calcium ion concentration</classLabel>
<newAxiom>'regulation of presynaptic cytosolic calcium ion concentration' EquivalentTo 'regulation of cytosolic calcium ion concentration' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse')</newAxiom>
<newAxiom>'regulation of presynaptic cytosolic calcium ion concentration' SubClassOf 'neuron cellular homeostasis'</newAxiom>
<newAxiom>'regulation of presynaptic cytosolic calcium ion concentration' SubClassOf 'regulation of cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'regulation of presynaptic cytosolic calcium ion concentration' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099508</classIRI>
<classLabel>voltage-gated ion channel activity involved in regulation of presynaptic membrane potential</classLabel>
<newAxiom>'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential' EquivalentTo 'voltage-gated ion channel activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential')</newAxiom>
<newAxiom>'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential'</newAxiom>
<newAxiom>'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynaptic membrane'</newAxiom>
<newAxiom>'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission'</newAxiom>
<newAxiom>'voltage-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf 'voltage-gated ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099507</classIRI>
<classLabel>ligand-gated ion channel activity involved in regulation of presynaptic membrane potential</classLabel>
<newAxiom>'ligand-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf 'ligand-gated ion channel activity'</newAxiom>
<newAxiom>'ligand-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynaptic membrane'</newAxiom>
<newAxiom>'ligand-gated ion channel activity involved in regulation of presynaptic membrane potential' EquivalentTo 'ligand-gated ion channel activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential')</newAxiom>
<newAxiom>'ligand-gated ion channel activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099506</classIRI>
<classLabel>synaptic vesicle transport along actin filament</classLabel>
<newAxiom>'synaptic vesicle transport along actin filament' SubClassOf 'vesicle transport along actin filament'</newAxiom>
<newAxiom>'synaptic vesicle transport along actin filament' SubClassOf 'synaptic vesicle cytoskeletal transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099505</classIRI>
<classLabel>regulation of presynaptic membrane potential</classLabel>
<newAxiom>'regulation of presynaptic membrane potential' SubClassOf 'regulation of membrane potential'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099504</classIRI>
<classLabel>synaptic vesicle cycle</classLabel>
<newAxiom>'synaptic vesicle cycle' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'synaptic vesicle cycle' SubClassOf 'transport'</newAxiom>
<newAxiom>'synaptic vesicle cycle' SubClassOf 'establishment of localization in cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099503</classIRI>
<classLabel>secretory vesicle</classLabel>
<newAxiom>'secretory vesicle' SubClassOf 'cytoplasmic, membrane-bounded vesicle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099502</classIRI>
<classLabel>calcium-dependent activation of synaptic vesicle fusion</classLabel>
<newAxiom>'calcium-dependent activation of synaptic vesicle fusion' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic vesicle exocytosis'</newAxiom>
<newAxiom>'calcium-dependent activation of synaptic vesicle fusion' SubClassOf 'positive regulation of synaptic vesicle fusion to presynaptic membrane'</newAxiom>
<newAxiom>'calcium-dependent activation of synaptic vesicle fusion' SubClassOf 'presynaptic process involved in synaptic transmission'</newAxiom>
<newAxiom>'calcium-dependent activation of synaptic vesicle fusion' SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some 'synaptic vesicle fusion to presynaptic active zone membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099501</classIRI>
<classLabel>exocytic vesicle membrane</classLabel>
<newAxiom>'exocytic vesicle membrane' SubClassOf 'transport vesicle membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099520</classIRI>
<classLabel>ion antiporter activity involved in regulation of presynaptic membrane potential</classLabel>
<newAxiom>'ion antiporter activity involved in regulation of presynaptic membrane potential' SubClassOf 'ion antiporter activity'</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential'</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of presynaptic membrane potential' EquivalentTo 'ion antiporter activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential')</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynaptic membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099521</classIRI>
<classLabel>ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential</classLabel>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynaptic membrane'</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential'</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential' EquivalentTo 'ATPase coupled ion transmembrane transporter activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic membrane potential')</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential' SubClassOf 'ATPase coupled ion transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099522</classIRI>
<classLabel>region of cytosol</classLabel>
<newAxiom>'region of cytosol' SubClassOf 'cytosol'</newAxiom>
<newAxiom>'region of cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol'</newAxiom>
<newAxiom>'region of cytosol' SubClassOf 'cytosolic part'</newAxiom>
<newAxiom>'region of cytosol' EquivalentTo 'cytosol' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099513</classIRI>
<classLabel>polymeric cytoskeletal fiber</classLabel>
<newAxiom>'polymeric cytoskeletal fiber' SubClassOf 'supramolecular fiber'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099512</classIRI>
<classLabel>supramolecular fiber</classLabel>
<newAxiom>'supramolecular fiber' SubClassOf 'cellular_component'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099515</classIRI>
<classLabel>actin filament-based transport</classLabel>
<newAxiom>'actin filament-based transport' SubClassOf 'cytoskeleton-dependent intracellular transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099514</classIRI>
<classLabel>synaptic vesicle cytoskeletal transport</classLabel>
<newAxiom>'synaptic vesicle cytoskeletal transport' SubClassOf 'vesicle cytoskeletal trafficking'</newAxiom>
<newAxiom>'synaptic vesicle cytoskeletal transport' SubClassOf 'synaptic vesicle transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099517</classIRI>
<classLabel>synaptic vesicle transport along microtubule</classLabel>
<newAxiom>'synaptic vesicle transport along microtubule' SubClassOf 'vesicle transport along microtubule'</newAxiom>
<newAxiom>'synaptic vesicle transport along microtubule' SubClassOf 'synaptic vesicle cytoskeletal transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099516</classIRI>
<classLabel>ion antiporter activity</classLabel>
<newAxiom>'ion antiporter activity' SubClassOf 'antiporter activity'</newAxiom>
<newAxiom>'ion antiporter activity' SubClassOf 'ion transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099519</classIRI>
<classLabel>dense core granule cytoskeletal trafficking</classLabel>
<newAxiom>'dense core granule cytoskeletal trafficking' SubClassOf 'vesicle cytoskeletal trafficking'</newAxiom>
<newAxiom>'dense core granule cytoskeletal trafficking' SubClassOf 'dense core granule transport'</newAxiom>
<newAxiom>'dense core granule cytoskeletal trafficking' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'axon'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099518</classIRI>
<classLabel>vesicle cytoskeletal trafficking</classLabel>
<newAxiom>'vesicle cytoskeletal trafficking' SubClassOf 'single-organism cellular localization'</newAxiom>
<newAxiom>'vesicle cytoskeletal trafficking' SubClassOf 'establishment of vesicle localization'</newAxiom>
<newAxiom>'vesicle cytoskeletal trafficking' SubClassOf 'cytoskeleton-dependent intracellular transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099532</classIRI>
<classLabel>synaptic vesicle processing via endosome</classLabel>
<newAxiom>'synaptic vesicle processing via endosome' SubClassOf 'endosomal transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099533</classIRI>
<classLabel>positive regulation of presynaptic cytosolic calcium concentration</classLabel>
<newAxiom>'positive regulation of presynaptic cytosolic calcium concentration' SubClassOf 'positive regulation of cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'positive regulation of presynaptic cytosolic calcium concentration' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'positive regulation of presynaptic cytosolic calcium concentration' EquivalentTo 'positive regulation of cytosolic calcium ion concentration' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse')</newAxiom>
<newAxiom>'positive regulation of presynaptic cytosolic calcium concentration' SubClassOf 'regulation of presynaptic cytosolic calcium ion concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099530</classIRI>
<classLabel>G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'G-protein coupled receptor activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G-protein coupled receptor activity'</newAxiom>
<newAxiom>'G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099531</classIRI>
<classLabel>presynaptic process involved in synaptic transmission</classLabel>
<newAxiom>'presynaptic process involved in synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'presynaptic process involved in synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission'</newAxiom>
<newAxiom>'presynaptic process involved in synaptic transmission' EquivalentTo 'biological_process' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission') and (http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse')</newAxiom>
<newAxiom>'presynaptic process involved in synaptic transmission' SubClassOf 'biological_process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099526</classIRI>
<classLabel>presynapse to nucleus signaling pathway</classLabel>
<newAxiom>'presynapse to nucleus signaling pathway' SubClassOf 'signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099525</classIRI>
<classLabel>presynaptic dense core granule exocytosis</classLabel>
<newAxiom>'presynaptic dense core granule exocytosis' SubClassOf 'dense core granule exocytosis'</newAxiom>
<newAxiom>'presynaptic dense core granule exocytosis' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099524</classIRI>
<classLabel>postsynaptic cytosol</classLabel>
<newAxiom>'postsynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol'</newAxiom>
<newAxiom>'postsynaptic cytosol' EquivalentTo 'cytosol' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol') and (http://purl.obolibrary.org/obo/BFO_0000050 some 'postsynapse')</newAxiom>
<newAxiom>'postsynaptic cytosol' SubClassOf 'synapse part'</newAxiom>
<newAxiom>'postsynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'postsynapse'</newAxiom>
<newAxiom>'postsynaptic cytosol' SubClassOf 'region of cytosol'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099523</classIRI>
<classLabel>presynaptic cytosol</classLabel>
<newAxiom>'presynaptic cytosol' SubClassOf 'region of cytosol'</newAxiom>
<newAxiom>'presynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'presynapse'</newAxiom>
<newAxiom>'presynaptic cytosol' SubClassOf 'synapse part'</newAxiom>
<newAxiom>'presynaptic cytosol' EquivalentTo 'cytosol' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol') and (http://purl.obolibrary.org/obo/BFO_0000050 some 'presynapse')</newAxiom>
<newAxiom>'presynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol'</newAxiom>
<newAxiom>'presynaptic cytosol' SubClassOf 'neuron part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099529</classIRI>
<classLabel>neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'chemical synaptic transmission, postsynaptic'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'neurotransmitter receptor activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099528</classIRI>
<classLabel>G-protein coupled neurotransmitter receptor activity</classLabel>
<newAxiom>'G-protein coupled neurotransmitter receptor activity' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity' SubClassOf 'G-protein coupled receptor activity'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'G-protein coupled receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099527</classIRI>
<classLabel>postsynapse to nucleus signaling pathway</classLabel>
<newAxiom>'postsynapse to nucleus signaling pathway' SubClassOf 'signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099538</classIRI>
<classLabel>synaptic signaling via neuropeptide</classLabel>
<newAxiom>'synaptic signaling via neuropeptide' SubClassOf 'synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099539</classIRI>
<classLabel>neuropeptide secretion from presynapse</classLabel>
<newAxiom>'neuropeptide secretion from presynapse' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic signaling via neuropeptide'</newAxiom>
<newAxiom>'neuropeptide secretion from presynapse' SubClassOf 'presynaptic dense core granule exocytosis'</newAxiom>
<newAxiom>'neuropeptide secretion from presynapse' SubClassOf 'peptide secretion'</newAxiom>
<newAxiom>'neuropeptide secretion from presynapse' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099536</classIRI>
<classLabel>synaptic signaling</classLabel>
<newAxiom>'synaptic signaling' SubClassOf 'cell-cell signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099537</classIRI>
<classLabel>trans-synaptic signaling</classLabel>
<newAxiom>'trans-synaptic signaling' SubClassOf 'synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099534</classIRI>
<classLabel>calcium ion binding involved in regulation of presynaptic cytosolic calcium levels</classLabel>
<newAxiom>'calcium ion binding involved in regulation of presynaptic cytosolic calcium levels' EquivalentTo 'calcium ion binding' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration')</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of presynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of presynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of presynaptic cytosolic calcium levels' SubClassOf 'calcium ion binding involved in regulation of cytosolic calcium ion concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099535</classIRI>
<classLabel>synapse associated extracellular matrix</classLabel>
<newAxiom>'synapse associated extracellular matrix' SubClassOf 'proteinaceous extracellular matrix'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099544</classIRI>
<classLabel>perisynaptic space</classLabel>
<newAxiom>'perisynaptic space' SubClassOf 'extracellular region'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099543</classIRI>
<classLabel>trans-synaptic signaling by soluble gas</classLabel>
<newAxiom>'trans-synaptic signaling by soluble gas' SubClassOf 'trans-synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099542</classIRI>
<classLabel>trans-synaptic signaling by endocannabinoid</classLabel>
<newAxiom>'trans-synaptic signaling by endocannabinoid' SubClassOf 'trans-synaptic signaling by lipid'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099541</classIRI>
<classLabel>trans-synaptic signaling by lipid</classLabel>
<newAxiom>'trans-synaptic signaling by lipid' SubClassOf 'trans-synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099540</classIRI>
<classLabel>trans-synaptic signaling by neuropeptide</classLabel>
<newAxiom>'trans-synaptic signaling by neuropeptide' SubClassOf 'synaptic signaling via neuropeptide'</newAxiom>
<newAxiom>'trans-synaptic signaling by neuropeptide' SubClassOf 'trans-synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099549</classIRI>
<classLabel>trans-synaptic signaling by carbon monoxide</classLabel>
<newAxiom>'trans-synaptic signaling by carbon monoxide' SubClassOf 'trans-synaptic signaling by soluble gas'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099545</classIRI>
<classLabel>trans-synaptic signaling by trans-synaptic complex</classLabel>
<newAxiom>'trans-synaptic signaling by trans-synaptic complex' SubClassOf 'trans-synaptic signaling'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099546</classIRI>
<classLabel>protein catabolic process, modulating synaptic transmission</classLabel>
<newAxiom>'protein catabolic process, modulating synaptic transmission' EquivalentTo 'protein catabolic process' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'protein catabolic process, modulating synaptic transmission' SubClassOf 'protein catabolic process'</newAxiom>
<newAxiom>'protein catabolic process, modulating synaptic transmission' SubClassOf 'modulation of synaptic transmission'</newAxiom>
<newAxiom>'protein catabolic process, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'protein catabolic process, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099547</classIRI>
<classLabel>regulation of translation at synapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of translation at synapse, modulating synaptic transmission' EquivalentTo 'regulation of translation' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of translation at synapse, modulating synaptic transmission' SubClassOf 'regulation of translation'</newAxiom>
<newAxiom>'regulation of translation at synapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'regulation of translation at synapse, modulating synaptic transmission' SubClassOf 'modulation of synaptic transmission'</newAxiom>
<newAxiom>'regulation of translation at synapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099548</classIRI>
<classLabel>trans-synaptic signaling by nitric oxide</classLabel>
<newAxiom>'trans-synaptic signaling by nitric oxide' SubClassOf 'trans-synaptic signaling by soluble gas'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099553</classIRI>
<classLabel>trans-synaptic signaling by endocannabinoid, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by endocannabinoid, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by lipid, modulating synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by endocannabinoid, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by endocannabinoid'</newAxiom>
<newAxiom>'trans-synaptic signaling by endocannabinoid, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099552</classIRI>
<classLabel>trans-synaptic signaling by lipid, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by lipid, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by lipid, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by lipid'</newAxiom>
<newAxiom>'trans-synaptic signaling by lipid, modulating synaptic transmission' SubClassOf 'trans-synaptic signalling, modulating synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099555</classIRI>
<classLabel>trans-synaptic signaling by nitric oxide, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by nitric oxide, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by soluble gas, modulating synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by nitric oxide, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by nitric oxide, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by nitric oxide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099554</classIRI>
<classLabel>trans-synaptic signaling by soluble gas, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by soluble gas, modulating synaptic transmission' SubClassOf 'trans-synaptic signalling, modulating synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by soluble gas, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by soluble gas'</newAxiom>
<newAxiom>'trans-synaptic signaling by soluble gas, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099551</classIRI>
<classLabel>trans-synaptic signaling by neuropeptide, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by neuropeptide, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by neuropeptide, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by neuropeptide'</newAxiom>
<newAxiom>'trans-synaptic signaling by neuropeptide, modulating synaptic transmission' SubClassOf 'trans-synaptic signalling, modulating synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099550</classIRI>
<classLabel>trans-synaptic signalling, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signalling, modulating synaptic transmission' EquivalentTo 'trans-synaptic signaling' and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'trans-synaptic signalling, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling'</newAxiom>
<newAxiom>'trans-synaptic signalling, modulating synaptic transmission' SubClassOf 'modulation of synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signalling, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099558</classIRI>
<classLabel>maintenance of synapse structure</classLabel>
<newAxiom>'maintenance of synapse structure' SubClassOf 'cellular component maintenance'</newAxiom>
<newAxiom>'maintenance of synapse structure' SubClassOf 'synapse organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099559</classIRI>
<classLabel>maintenance of alignment of postsynaptic density and presynaptic active zone</classLabel>
<newAxiom>'maintenance of alignment of postsynaptic density and presynaptic active zone' SubClassOf 'maintenance of synapse structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099556</classIRI>
<classLabel>trans-synaptic signaling by carbon monoxide, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by carbon monoxide, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by carbon monoxide, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by soluble gas, modulating synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by carbon monoxide, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by carbon monoxide'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099557</classIRI>
<classLabel>trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission</classLabel>
<newAxiom>'trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission' SubClassOf 'trans-synaptic signaling by trans-synaptic complex'</newAxiom>
<newAxiom>'trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission' SubClassOf 'trans-synaptic signalling, modulating synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099562</classIRI>
<classLabel>maintenance of postsynaptic density structure</classLabel>
<newAxiom>'maintenance of postsynaptic density structure' SubClassOf 'postsynaptic density organization'</newAxiom>
<newAxiom>'maintenance of postsynaptic density structure' SubClassOf 'maintenance of synapse structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099561</classIRI>
<classLabel>synaptic membrane adhesion to extracellular matrix</classLabel>
<newAxiom>'synaptic membrane adhesion to extracellular matrix' SubClassOf 'cell-matrix adhesion'</newAxiom>
<newAxiom>'synaptic membrane adhesion to extracellular matrix' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'maintenance of synapse structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099560</classIRI>
<classLabel>synaptic membrane adhesion</classLabel>
<newAxiom>'synaptic membrane adhesion' SubClassOf 'cell-cell adhesion via plasma-membrane adhesion molecules'</newAxiom>
<newAxiom>'synaptic membrane adhesion' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'maintenance of synapse structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099566</classIRI>
<classLabel>regulation of postsynaptic cytosolic calcium ion concentration</classLabel>
<newAxiom>'regulation of postsynaptic cytosolic calcium ion concentration' SubClassOf 'regulation of cytosolic calcium ion concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099565</classIRI>
<classLabel>chemical synaptic transmission, postsynaptic</classLabel>
<newAxiom>'chemical synaptic transmission, postsynaptic' SubClassOf 'cell surface receptor signaling pathway'</newAxiom>
<newAxiom>'chemical synaptic transmission, postsynaptic' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission'</newAxiom>
<newAxiom>'chemical synaptic transmission, postsynaptic' EquivalentTo 'cell surface receptor signaling pathway' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic transmission') and (http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse')</newAxiom>
<newAxiom>'chemical synaptic transmission, postsynaptic' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099564</classIRI>
<classLabel>modification of synaptic structure, modulating synaptic transmission</classLabel>
<newAxiom>'modification of synaptic structure, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'modification of synaptic structure, modulating synaptic transmission' SubClassOf 'modification of synaptic structure'</newAxiom>
<newAxiom>'modification of synaptic structure, modulating synaptic transmission' SubClassOf 'modulation of synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099563</classIRI>
<classLabel>modification of synaptic structure</classLabel>
<newAxiom>'modification of synaptic structure' SubClassOf 'synapse organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099567</classIRI>
<classLabel>calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels</classLabel>
<newAxiom>'calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf 'calcium ion binding involved in regulation of cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels' EquivalentTo 'calcium ion binding' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic cytosolic calcium ion concentration')</newAxiom>
<newAxiom>'calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic cytosolic calcium ion concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099568</classIRI>
<classLabel>cytoplasmic region</classLabel>
<newAxiom>'cytoplasmic region' SubClassOf 'cytoplasm'</newAxiom>
<newAxiom>'cytoplasmic region' SubClassOf 'cytoplasmic part'</newAxiom>
<newAxiom>'cytoplasmic region' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytoplasm'</newAxiom>
<newAxiom>'cytoplasmic region' EquivalentTo 'cytoplasm' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'cytoplasm')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099569</classIRI>
<classLabel>presynaptic cytoskeleton</classLabel>
<newAxiom>'presynaptic cytoskeleton' EquivalentTo 'cytoskeleton' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'presynapse')</newAxiom>
<newAxiom>'presynaptic cytoskeleton' SubClassOf 'neuron part'</newAxiom>
<newAxiom>'presynaptic cytoskeleton' SubClassOf 'cytoskeleton'</newAxiom>
<newAxiom>'presynaptic cytoskeleton' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'presynapse'</newAxiom>
<newAxiom>'presynaptic cytoskeleton' SubClassOf 'synapse part'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099571</classIRI>
<classLabel>postsynaptic cytoskeleton</classLabel>
<newAxiom>'postsynaptic cytoskeleton' SubClassOf 'cytoskeleton'</newAxiom>
<newAxiom>'postsynaptic cytoskeleton' SubClassOf 'synapse part'</newAxiom>
<newAxiom>'postsynaptic cytoskeleton' EquivalentTo 'cytoskeleton' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'postsynapse')</newAxiom>
<newAxiom>'postsynaptic cytoskeleton' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'postsynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099573</classIRI>
<classLabel>glutamatergic postsynaptic density</classLabel>
<newAxiom>'glutamatergic postsynaptic density' SubClassOf 'neuronal postsynaptic density'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099572</classIRI>
<classLabel>postsynaptic specialization</classLabel>
<newAxiom>'postsynaptic specialization' SubClassOf 'synapse part'</newAxiom>
<newAxiom>'postsynaptic specialization' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'postsynapse'</newAxiom>
<newAxiom>'postsynaptic specialization' SubClassOf 'intracellular non-membrane-bounded organelle'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099575</classIRI>
<classLabel>regulation of protein catabolic process at presynapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of protein catabolic process at presynapse, modulating synaptic transmission' SubClassOf 'regulation of protein catabolic process at synapse, modulating synaptic transmission'</newAxiom>
<newAxiom>'regulation of protein catabolic process at presynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'regulation of protein catabolic process at presynapse, modulating synaptic transmission' EquivalentTo 'regulation of protein catabolic process' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of protein catabolic process at presynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099574</classIRI>
<classLabel>regulation of protein catabolic process at synapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of protein catabolic process at synapse, modulating synaptic transmission' SubClassOf 'regulation of protein catabolic process'</newAxiom>
<newAxiom>'regulation of protein catabolic process at synapse, modulating synaptic transmission' SubClassOf 'modulation of synaptic transmission'</newAxiom>
<newAxiom>'regulation of protein catabolic process at synapse, modulating synaptic transmission' EquivalentTo 'regulation of protein catabolic process' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of protein catabolic process at synapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
<newAxiom>'regulation of protein catabolic process at synapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'synapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099577</classIRI>
<classLabel>regulation of translation at presynapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of translation at presynapse, modulating synaptic transmission' SubClassOf 'regulation of translation at synapse, modulating synaptic transmission'</newAxiom>
<newAxiom>'regulation of translation at presynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'regulation of translation at presynapse, modulating synaptic transmission' EquivalentTo 'regulation of translation' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of translation at presynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099576</classIRI>
<classLabel>regulation of protein catabolic process at postsynapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of protein catabolic process at postsynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse'</newAxiom>
<newAxiom>'regulation of protein catabolic process at postsynapse, modulating synaptic transmission' SubClassOf 'regulation of protein catabolic process at synapse, modulating synaptic transmission'</newAxiom>
<newAxiom>'regulation of protein catabolic process at postsynapse, modulating synaptic transmission' EquivalentTo 'regulation of protein catabolic process' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of protein catabolic process at postsynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099579</classIRI>
<classLabel>G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'G-protein coupled neurotransmitter receptor activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential')</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf 'G-protein coupled neurotransmitter receptor activity'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099578</classIRI>
<classLabel>regulation of translation at postsynapse, modulating synaptic transmission</classLabel>
<newAxiom>'regulation of translation at postsynapse, modulating synaptic transmission' SubClassOf 'regulation of translation at synapse, modulating synaptic transmission'</newAxiom>
<newAxiom>'regulation of translation at postsynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse'</newAxiom>
<newAxiom>'regulation of translation at postsynapse, modulating synaptic transmission' EquivalentTo 'regulation of translation' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse') and (http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission')</newAxiom>
<newAxiom>'regulation of translation at postsynapse, modulating synaptic transmission' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'synaptic transmission'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099588</classIRI>
<classLabel>positive regulation of postsynaptic cytosolic calcium concentration</classLabel>
<newAxiom>'positive regulation of postsynaptic cytosolic calcium concentration' SubClassOf 'positive regulation of cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'positive regulation of postsynaptic cytosolic calcium concentration' EquivalentTo 'positive regulation of cytosolic calcium ion concentration' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse')</newAxiom>
<newAxiom>'positive regulation of postsynaptic cytosolic calcium concentration' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099585</classIRI>
<classLabel>release of sequestered calcium ion into presynaptic cytosol</classLabel>
<newAxiom>'release of sequestered calcium ion into presynaptic cytosol' SubClassOf 'release of sequestered calcium ion into cytosol'</newAxiom>
<newAxiom>'release of sequestered calcium ion into presynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynapse'</newAxiom>
<newAxiom>'release of sequestered calcium ion into presynaptic cytosol' SubClassOf 'positive regulation of presynaptic cytosolic calcium concentration'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099586</classIRI>
<classLabel>release of sequestered calcium ion into postsynaptic cytosol</classLabel>
<newAxiom>'release of sequestered calcium ion into postsynaptic cytosol' SubClassOf 'positive regulation of postsynaptic cytosolic calcium concentration'</newAxiom>
<newAxiom>'release of sequestered calcium ion into postsynaptic cytosol' SubClassOf 'release of sequestered calcium ion into cytosol'</newAxiom>
<newAxiom>'release of sequestered calcium ion into postsynaptic cytosol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynapse'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099583</classIRI>
<classLabel>neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels</classLabel>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf 'receptor signaling protein activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' EquivalentTo 'neurotransmitter receptor activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic cytosolic calcium ion concentration')</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'chemical synaptic transmission, postsynaptic'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099581</classIRI>
<classLabel>ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential' SubClassOf 'ATPase coupled ion transmembrane transporter activity'</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'ATPase coupled ion transmembrane transporter activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099582</classIRI>
<classLabel>neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels</classLabel>
<newAxiom>'neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels' SubClassOf 'receptor signaling protein activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'presynaptic membrane'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels' SubClassOf 'neurotransmitter receptor activity'</newAxiom>
<newAxiom>'neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels' EquivalentTo 'neurotransmitter receptor activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of presynaptic cytosolic calcium ion concentration')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099580</classIRI>
<classLabel>ion antiporter activity involved in regulation of postsynaptic membrane potential</classLabel>
<newAxiom>'ion antiporter activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'postsynaptic membrane'</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of postsynaptic membrane potential' SubClassOf 'ion antiporter activity'</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of postsynaptic membrane potential' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential'</newAxiom>
<newAxiom>'ion antiporter activity involved in regulation of postsynaptic membrane potential' EquivalentTo 'ion antiporter activity' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'regulation of postsynaptic membrane potential')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099589</classIRI>
<classLabel>serotonin receptor activity</classLabel>
<newAxiom>'serotonin receptor activity' SubClassOf 'transmembrane signaling receptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099592</classIRI>
<classLabel>endocytosed synaptic vesicle processing via endosome</classLabel>
<newAxiom>'endocytosed synaptic vesicle processing via endosome' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic vesicle recycling via endosome'</newAxiom>
<newAxiom>'endocytosed synaptic vesicle processing via endosome' SubClassOf 'synaptic vesicle processing via endosome'</newAxiom>
<newAxiom>'endocytosed synaptic vesicle processing via endosome' EquivalentTo 'synaptic vesicle processing via endosome' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic vesicle recycling via endosome')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099593</classIRI>
<classLabel>endocytosed synaptic vesicle to endosome fusion</classLabel>
<newAxiom>'endocytosed synaptic vesicle to endosome fusion' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic vesicle recycling via endosome'</newAxiom>
<newAxiom>'endocytosed synaptic vesicle to endosome fusion' EquivalentTo 'synaptic vesicle to endosome fusion' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'synaptic vesicle recycling via endosome')</newAxiom>
<newAxiom>'endocytosed synaptic vesicle to endosome fusion' SubClassOf 'synaptic vesicle to endosome fusion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099590</classIRI>
<classLabel>neurotransmitter receptor internalization</classLabel>
<newAxiom>'neurotransmitter receptor internalization' SubClassOf 'receptor internalization'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>