<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
135
</numberChangedClasses>
<numberNewClasses>
4
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071875</classIRI>
<classLabel>adrenergic receptor signaling pathway</classLabel>
<deletedAxiom>&apos;adrenergic receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adrenergic receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007206</classIRI>
<classLabel>phospholipase C-activating G protein-coupled glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;phospholipase C-activating G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;PLC activating G protein-coupled glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007208</classIRI>
<classLabel>phospholipase C-activating serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;phospholipase C-activating serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Gq/11-coupled serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010856</classIRI>
<classLabel>adenylate cyclase activator activity</classLabel>
<deletedAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;adenylate cyclase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010858</classIRI>
<classLabel>calcium-dependent protein kinase regulator activity</classLabel>
<deletedAxiom>&apos;calcium-dependent protein kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium-dependent protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007210</classIRI>
<classLabel>serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007213</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled acetylcholine receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007215</classIRI>
<classLabel>glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007216</classIRI>
<classLabel>G protein-coupled glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019207</classIRI>
<classLabel>kinase regulator activity</classLabel>
<deletedAxiom>&apos;kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<deletedAxiom>&apos;kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019211</classIRI>
<classLabel>phosphatase activator activity</classLabel>
<deletedAxiom>&apos;phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019212</classIRI>
<classLabel>phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046861</classIRI>
<classLabel>glyoxysomal membrane</classLabel>
<deletedAxiom>&apos;glyoxysomal membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;glyoxysome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019243</classIRI>
<classLabel>methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione</classLabel>
<deletedAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactoylglutathione lyase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;hydroxyacylglutathione hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019248</classIRI>
<classLabel>D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde</classLabel>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;methylglyoxal reductase (NADH-dependent) activity&apos;</deletedAxiom>
<deletedAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046785</classIRI>
<classLabel>microtubule polymerization</classLabel>
<deletedAxiom>&apos;microtubule polymerization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;microtubule nucleation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007186</classIRI>
<classLabel>G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007196</classIRI>
<classLabel>adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007198</classIRI>
<classLabel>adenylate cyclase-inhibiting serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;adenylate cyclase-inhibiting serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Gi/o-coupled serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010706</classIRI>
<classLabel>ganglioside biosynthetic process via lactosylceramide</classLabel>
<deletedAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactosylceramide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010707</classIRI>
<classLabel>globoside biosynthetic process via lactosylceramide</classLabel>
<deletedAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactosylceramide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0095500</classIRI>
<classLabel>acetylcholine receptor signaling pathway</classLabel>
<deletedAxiom>&apos;acetylcholine receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009555</classIRI>
<classLabel>pollen development</classLabel>
<deletedAxiom>&apos;pollen development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;microsporogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009255</classIRI>
<classLabel>Entner-Doudoroff pathway through 6-phosphogluconate</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009298</classIRI>
<classLabel>GDP-mannose biosynthetic process</classLabel>
<deletedAxiom>&apos;GDP-mannose biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose-phosphate guanylyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061857</classIRI>
<classLabel>endoplasmic reticulum stress-induced pre-emptive quality control</classLabel>
<deletedAxiom>&apos;endoplasmic reticulum stress-induced pre-emptive quality control&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;proteasome-mediated ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061719</classIRI>
<classLabel>glucose catabolic process to pyruvate utilizing ADP</classLabel>
<deletedAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ADP-specific glucokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;</deletedAxiom>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061721</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)</classLabel>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;</deletedAxiom>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;3-sulfolactaldehyde reductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061720</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde</classLabel>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-deoxy-6-sulfofructose-1-phosphate aldolase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sulfoquinovose isomerase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061729</classIRI>
<classLabel>GDP-mannose biosynthetic process from fructose-6-phosphate</classLabel>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose-6-phosphate isomerase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061728</classIRI>
<classLabel>GDP-mannose biosynthetic process from mannose</classLabel>
<deletedAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061705</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate through glucose and fructose</classLabel>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose-6-phosphate isomerase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sucrose alpha-glucosidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061706</classIRI>
<classLabel>glycolytic process from sucrose through glucose and fructose</classLabel>
<deletedAxiom>&apos;glycolytic process from sucrose through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061762</classIRI>
<classLabel>CAMKK-AMPK signaling cascade</classLabel>
<deletedAxiom>&apos;CAMKK-AMPK signaling cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;AMP-activated protein kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;CAMKK-AMPK signaling cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;calcium ion binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061732</classIRI>
<classLabel>mitochondrial acetyl-CoA biosynthetic process from pyruvate</classLabel>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mitochondrial pyruvate transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial acetyl-CoA biosynthetic process from pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061739</classIRI>
<classLabel>protein lipidation involved in autophagosome assembly</classLabel>
<deletedAxiom>&apos;protein lipidation involved in autophagosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Atg8 ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009051</classIRI>
<classLabel>pentose-phosphate shunt, oxidative branch</classLabel>
<deletedAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose-6-phosphate dehydrogenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphogluconate dehydrogenase (decarboxylating) activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061633</classIRI>
<classLabel>transport-coupled glycolytic process through glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;transport-coupled glycolytic process through glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061613</classIRI>
<classLabel>glycolytic process from glycerol</classLabel>
<deletedAxiom>&apos;glycolytic process from glycerol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol to glycerone phosphate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061612</classIRI>
<classLabel>galactose to glucose-1-phosphate metabolic process</classLabel>
<deletedAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;UTP:galactose-1-phosphate uridylyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;galactokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061611</classIRI>
<classLabel>mannose to fructose-6-phosphate metabolic process</classLabel>
<deletedAxiom>&apos;mannose to fructose-6-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose-6-phosphate isomerase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;mannose to fructose-6-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061610</classIRI>
<classLabel>glycerol to glycerone phosphate metabolic process</classLabel>
<deletedAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061616</classIRI>
<classLabel>glycolytic process from fructose through fructose-6-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process from fructose through fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fructokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061619</classIRI>
<classLabel>glycolytic process from mannose through fructose-6-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process from mannose through fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose to fructose-6-phosphate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061624</classIRI>
<classLabel>fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate</classLabel>
<deletedAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ketohexokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061623</classIRI>
<classLabel>glycolytic process from galactose</classLabel>
<deletedAxiom>&apos;glycolytic process from galactose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;galactose to glucose-1-phosphate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<deletedAxiom>&apos;canonical glycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucokinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061625</classIRI>
<classLabel>glycolytic process through fructose-1-phosphate</classLabel>
<deletedAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061681</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061680</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-D-gluconate aldolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061684</classIRI>
<classLabel>chaperone-mediated autophagy</classLabel>
<deletedAxiom>&apos;chaperone-mediated autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;chaperone binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061688</classIRI>
<classLabel>glycolytic process via Entner-Doudoroff Pathway</classLabel>
<deletedAxiom>&apos;glycolytic process via Entner-Doudoroff Pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Entner-Doudoroff pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061575</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase activator activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein serine/threonine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0012501</classIRI>
<classLabel>programmed cell death</classLabel>
<deletedAxiom>&apos;programmed cell death&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000139</classIRI>
<classLabel>Golgi membrane</classLabel>
<deletedAxiom>&apos;Golgi membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Golgi subcompartment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099602</classIRI>
<classLabel>neurotransmitter receptor regulator activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036008</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate</classLabel>
<deletedAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099501</classIRI>
<classLabel>exocytic vesicle membrane</classLabel>
<deletedAxiom>&apos;exocytic vesicle membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;exocytic vesicle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000075</classIRI>
<classLabel>cell cycle checkpoint</classLabel>
<deletedAxiom>&apos;cell cycle checkpoint&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000045</classIRI>
<classLabel>autophagosome assembly</classLabel>
<deletedAxiom>&apos;autophagosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Atg1/ULK1 kinase complex assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<deletedAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004861</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein serine/threonine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004865</classIRI>
<classLabel>protein serine/threonine phosphatase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein serine/threonine phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein serine/threonine phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein serine/threonine phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein serine/threonine phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903349</classIRI>
<classLabel>omegasome membrane</classLabel>
<deletedAxiom>&apos;omegasome membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;omegasome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099104</classIRI>
<classLabel>potassium channel activator activity</classLabel>
<deletedAxiom>&apos;potassium channel activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;potassium channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099103</classIRI>
<classLabel>channel activator activity</classLabel>
<deletedAxiom>&apos;channel activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099106</classIRI>
<classLabel>ion channel regulator activity</classLabel>
<deletedAxiom>&apos;ion channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ion channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090741</classIRI>
<classLabel>pigment granule membrane</classLabel>
<deletedAxiom>&apos;pigment granule membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;pigment granule&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038171</classIRI>
<classLabel>cannabinoid signaling pathway</classLabel>
<deletedAxiom>&apos;cannabinoid signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;cannabinoid receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016538</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase regulator activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein serine/threonine kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090382</classIRI>
<classLabel>phagosome maturation</classLabel>
<deletedAxiom>&apos;phagosome maturation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;exocytosis&apos;</deletedAxiom>
<deletedAxiom>&apos;phagosome maturation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phagolysosome assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006915</classIRI>
<classLabel>apoptotic process</classLabel>
<deletedAxiom>&apos;apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;execution phase of apoptosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006914</classIRI>
<classLabel>autophagy</classLabel>
<deletedAxiom>&apos;autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016236</classIRI>
<classLabel>macroautophagy</classLabel>
<deletedAxiom>&apos;macroautophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;autophagosome assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016247</classIRI>
<classLabel>channel regulator activity</classLabel>
<deletedAxiom>&apos;channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006635</classIRI>
<classLabel>fatty acid beta-oxidation</classLabel>
<deletedAxiom>&apos;fatty acid beta-oxidation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fatty acid ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006657</classIRI>
<classLabel>CDP-choline pathway</classLabel>
<deletedAxiom>&apos;CDP-choline pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;choline kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;CDP-choline pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;diacylglycerol cholinephosphotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006511</classIRI>
<classLabel>ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;ubiquitin-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006412</classIRI>
<classLabel>translation</classLabel>
<deletedAxiom>&apos;translation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;translational termination&apos;</deletedAxiom>
<deletedAxiom>&apos;translation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;translational initiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006413</classIRI>
<classLabel>translational initiation</classLabel>
<deletedAxiom>&apos;translational initiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;formation of translation initiation ternary complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070914</classIRI>
<classLabel>UV-damage excision repair</classLabel>
<deletedAxiom>&apos;UV-damage excision repair&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;UV-damage excision repair, DNA incision&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031147</classIRI>
<classLabel>1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process</classLabel>
<deletedAxiom>&apos;1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;DIF dechlorinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<deletedAxiom>&apos;glycolytic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006098</classIRI>
<classLabel>pentose-phosphate shunt</classLabel>
<deletedAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pentose-phosphate shunt, oxidative branch&apos;</deletedAxiom>
<deletedAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pentose-phosphate shunt, non-oxidative branch&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008427</classIRI>
<classLabel>calcium-dependent protein kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;calcium-dependent protein kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcium-dependent protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008200</classIRI>
<classLabel>ion channel inhibitor activity</classLabel>
<deletedAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ion channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<deletedAxiom>&apos;enzyme activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035585</classIRI>
<classLabel>calcium-mediated signaling using extracellular calcium source</classLabel>
<deletedAxiom>&apos;calcium-mediated signaling using extracellular calcium source&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;calcium ion import across plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035584</classIRI>
<classLabel>calcium-mediated signaling using intracellular calcium source</classLabel>
<deletedAxiom>&apos;calcium-mediated signaling using intracellular calcium source&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;release of sequestered calcium ion into cytosol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072542</classIRI>
<classLabel>protein phosphatase activator activity</classLabel>
<deletedAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098989</classIRI>
<classLabel>NMDA selective glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;NMDA selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;NMDA glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098990</classIRI>
<classLabel>AMPA selective glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;AMPA selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;AMPA glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098991</classIRI>
<classLabel>kainate selective glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;kainate selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;kainate selective glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060271</classIRI>
<classLabel>cilium assembly</classLabel>
<deletedAxiom>&apos;cilium assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ciliary basal body-plasma membrane docking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098852</classIRI>
<classLabel>lytic vacuole membrane</classLabel>
<deletedAxiom>&apos;lytic vacuole membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lytic vacuole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098876</classIRI>
<classLabel>vesicle-mediated transport to the plasma membrane</classLabel>
<deletedAxiom>&apos;vesicle-mediated transport to the plasma membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;exocytosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035209</classIRI>
<classLabel>pupal development</classLabel>
<deletedAxiom>&apos;pupal development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;apolysis&apos;</deletedAxiom>
<deletedAxiom>&apos;pupal development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;eclosion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098804</classIRI>
<classLabel>non-motile cilium membrane</classLabel>
<deletedAxiom>&apos;non-motile cilium membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;non-motile cilium&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035235</classIRI>
<classLabel>ionotropic glutamate receptor signaling pathway</classLabel>
<deletedAxiom>&apos;ionotropic glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ionotropic glutamate receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098826</classIRI>
<classLabel>endoplasmic reticulum tubular network membrane</classLabel>
<deletedAxiom>&apos;endoplasmic reticulum tubular network membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endoplasmic reticulum tubular network&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098772</classIRI>
<classLabel>molecular function regulator</classLabel>
<deletedAxiom>&apos;molecular function regulator&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;molecular_function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001881</classIRI>
<classLabel>receptor recycling</classLabel>
<deletedAxiom>&apos;receptor recycling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098664</classIRI>
<classLabel>G protein-coupled serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904930</classIRI>
<classLabel>amphisome membrane</classLabel>
<deletedAxiom>&apos;amphisome membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;amphisome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005789</classIRI>
<classLabel>endoplasmic reticulum membrane</classLabel>
<deletedAxiom>&apos;endoplasmic reticulum membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endoplasmic reticulum subcompartment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>receptor regulator activity</classLabel>
<deletedAxiom>&apos;receptor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030549</classIRI>
<classLabel>acetylcholine receptor activator activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030550</classIRI>
<classLabel>acetylcholine receptor inhibitor activity</classLabel>
<deletedAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;acetylcholine receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019941</classIRI>
<classLabel>modification-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;modification-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein modification process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030292</classIRI>
<classLabel>protein tyrosine kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<deletedAxiom>&apos;protein kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030296</classIRI>
<classLabel>protein tyrosine kinase activator activity</classLabel>
<deletedAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030297</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activator activity</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030298</classIRI>
<classLabel>receptor signaling protein tyrosine kinase activator activity</classLabel>
<newAxiom>&apos;receptor signaling protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030291</classIRI>
<classLabel>protein serine/threonine kinase inhibitor activity</classLabel>
<deletedAxiom>&apos;protein serine/threonine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019888</classIRI>
<classLabel>protein phosphatase regulator activity</classLabel>
<deletedAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005246</classIRI>
<classLabel>calcium channel regulator activity</classLabel>
<deletedAxiom>&apos;calcium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030234</classIRI>
<classLabel>enzyme regulator activity</classLabel>
<deletedAxiom>&apos;enzyme regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0101003</classIRI>
<classLabel>ficolin-1-rich granule membrane</classLabel>
<deletedAxiom>&apos;ficolin-1-rich granule membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ficolin-1-rich granule&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0101004</classIRI>
<classLabel>cytolytic granule membrane</classLabel>
<deletedAxiom>&apos;cytolytic granule membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytolytic granule&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019650</classIRI>
<classLabel>glycolytic fermentation to butanediol</classLabel>
<deletedAxiom>&apos;glycolytic fermentation to butanediol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;(R,R)-butanediol dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019655</classIRI>
<classLabel>glycolytic fermentation to ethanol</classLabel>
<deletedAxiom>&apos;glycolytic fermentation to ethanol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycolytic process through fructose-6-phosphate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019657</classIRI>
<classLabel>glycolytic fermentation to propionate</classLabel>
<deletedAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;transport-coupled glycolytic process through glucose-6-phosphate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019660</classIRI>
<classLabel>glycolytic fermentation</classLabel>
<deletedAxiom>&apos;glycolytic fermentation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycolytic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019661</classIRI>
<classLabel>glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;L(+)-lactate biosynthetic process from pyruvate&apos;</deletedAxiom>
<deletedAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;canonical glycolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017020</classIRI>
<classLabel>myosin phosphatase regulator activity</classLabel>
<deletedAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;myosin phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005085</classIRI>
<classLabel>guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;GTP binding&apos;</deletedAxiom>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;GDP binding&apos;</deletedAxiom>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;GDP binding&apos;</deletedAxiom>
<deletedAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;GTP binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032591</classIRI>
<classLabel>dendritic spine membrane</classLabel>
<deletedAxiom>&apos;dendritic spine membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;dendritic spine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032590</classIRI>
<classLabel>dendrite membrane</classLabel>
<deletedAxiom>&apos;dendrite membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;dendrite&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019574</classIRI>
<classLabel>sucrose catabolic process via 3&apos;-ketosucrose</classLabel>
<deletedAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucoside 3-dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032586</classIRI>
<classLabel>protein storage vacuole membrane</classLabel>
<deletedAxiom>&apos;protein storage vacuole membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein storage vacuole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007340</classIRI>
<classLabel>acrosome reaction</classLabel>
<deletedAxiom>&apos;acrosome reaction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;acrosomal vesicle exocytosis&apos;</deletedAxiom>
<deletedAxiom>&apos;acrosome reaction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;membrane fusion involved in acrosome reaction&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110133</classIRI>
<classLabel>negative regulation of CRISPR-cas system</classLabel>
<newAxiom>'negative regulation of CRISPR-cas system' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'CRISPR-cas system')</newAxiom>
<newAxiom>'negative regulation of CRISPR-cas system' SubClassOf 'negative regulation of defense response'</newAxiom>
<newAxiom>'negative regulation of CRISPR-cas system' SubClassOf 'regulation of CRISPR-cas system'</newAxiom>
<newAxiom>'negative regulation of CRISPR-cas system' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'CRISPR-cas system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110132</classIRI>
<classLabel>regulation of CRISPR-cas system</classLabel>
<newAxiom>'regulation of CRISPR-cas system' SubClassOf 'regulation of defense response'</newAxiom>
<newAxiom>'regulation of CRISPR-cas system' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002211 some 'CRISPR-cas system')</newAxiom>
<newAxiom>'regulation of CRISPR-cas system' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'CRISPR-cas system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106155</classIRI>
<classLabel>peptidyl-lysine 3-dioxygenase activity</classLabel>
<newAxiom>'peptidyl-lysine 3-dioxygenase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors'</newAxiom>
<newAxiom>'peptidyl-lysine 3-dioxygenase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062092</classIRI>
<classLabel>Yae1-Lto1 complex</classLabel>
<newAxiom>'Yae1-Lto1 complex' SubClassOf 'protein-containing complex'</newAxiom>
<newAxiom>'Yae1-Lto1 complex' SubClassOf 'cytosolic part'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>