<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
135
</numberChangedClasses>
<numberNewClasses>
8
</numberNewClasses>
<numberDeletedClasses>
9
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046610</classIRI>
<classLabel>lysosomal proton-transporting V-type ATPase, V0 domain</classLabel>
<deletedAxiom>&apos;lysosomal proton-transporting V-type ATPase, V0 domain&apos; EquivalentTo &apos;proton-transporting V-type ATPase, V0 domain&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lysosome&apos;)</deletedAxiom>
<newAxiom>&apos;lysosomal proton-transporting V-type ATPase, V0 domain&apos; EquivalentTo &apos;proton-transporting V-type ATPase, V0 domain&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lysosomal membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046611</classIRI>
<classLabel>lysosomal proton-transporting V-type ATPase complex</classLabel>
<deletedAxiom>&apos;lysosomal proton-transporting V-type ATPase complex&apos; EquivalentTo &apos;proton-transporting V-type ATPase complex&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lysosome&apos;)</deletedAxiom>
<newAxiom>&apos;lysosomal proton-transporting V-type ATPase complex&apos; EquivalentTo &apos;proton-transporting V-type ATPase complex&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lysosomal membrane&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034516</classIRI>
<classLabel>response to vitamin B6</classLabel>
<newAxiom>&apos;response to vitamin B6&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034401</classIRI>
<classLabel>chromatin organization involved in regulation of transcription</classLabel>
<deletedAxiom>&apos;chromatin organization involved in regulation of transcription&apos; SubClassOf &apos;chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin organization involved in regulation of transcription&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of transcription, DNA-templated&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin organization involved in regulation of transcription&apos; EquivalentTo &apos;chromatin organization&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of transcription, DNA-templated&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071302</classIRI>
<classLabel>cellular response to vitamin B2</classLabel>
<newAxiom>&apos;cellular response to vitamin B2&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071301</classIRI>
<classLabel>cellular response to vitamin B1</classLabel>
<newAxiom>&apos;cellular response to vitamin B1&apos; SubClassOf &apos;cellular response to alcohol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071304</classIRI>
<classLabel>cellular response to vitamin B6</classLabel>
<newAxiom>&apos;cellular response to vitamin B6&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071308</classIRI>
<classLabel>cellular response to menaquinone</classLabel>
<deletedAxiom>&apos;cellular response to menaquinone&apos; SubClassOf &apos;cellular response to ketone&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to menaquinone&apos; SubClassOf &apos;cellular response to vitamin K&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071307</classIRI>
<classLabel>cellular response to vitamin K</classLabel>
<newAxiom>&apos;cellular response to vitamin K&apos; SubClassOf &apos;cellular response to ketone&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071309</classIRI>
<classLabel>cellular response to phylloquinone</classLabel>
<deletedAxiom>&apos;cellular response to phylloquinone&apos; SubClassOf &apos;cellular response to ketone&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to phylloquinone&apos; SubClassOf &apos;cellular response to vitamin K&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071298</classIRI>
<classLabel>cellular response to L-ascorbic acid</classLabel>
<newAxiom>&apos;cellular response to L-ascorbic acid&apos; SubClassOf &apos;cellular response to organic cyclic compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071297</classIRI>
<classLabel>cellular response to cobalamin</classLabel>
<newAxiom>&apos;cellular response to cobalamin&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009229</classIRI>
<classLabel>thiamine diphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;aromatic compound biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;pyrimidine-containing compound biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;thiamine-containing compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009228</classIRI>
<classLabel>thiamine biosynthetic process</classLabel>
<newAxiom>&apos;thiamine biosynthetic process&apos; SubClassOf &apos;primary alcohol biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009230</classIRI>
<classLabel>thiamine catabolic process</classLabel>
<newAxiom>&apos;thiamine catabolic process&apos; SubClassOf &apos;primary alcohol catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010266</classIRI>
<classLabel>response to vitamin B1</classLabel>
<newAxiom>&apos;response to vitamin B1&apos; SubClassOf &apos;response to alcohol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061587</classIRI>
<classLabel>transfer RNA gene-mediated silencing</classLabel>
<deletedAxiom>&apos;transfer RNA gene-mediated silencing&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;transfer RNA gene-mediated silencing&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<newAxiom>&apos;transfer RNA gene-mediated silencing&apos; SubClassOf &apos;pre-transcriptional gene silencing by RNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097549</classIRI>
<classLabel>chromatin organization involved in negative regulation of transcription</classLabel>
<deletedAxiom>&apos;chromatin organization involved in negative regulation of transcription&apos; SubClassOf &apos;chromatin organization involved in regulation of transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin organization involved in negative regulation of transcription&apos; EquivalentTo &apos;chromatin organization&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;negative regulation of transcription, DNA-templated&apos;)</deletedAxiom>
<deletedAxiom>&apos;chromatin organization involved in negative regulation of transcription&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;negative regulation of transcription, DNA-templated&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048502</classIRI>
<classLabel>ABC-type thiamine transporter activity</classLabel>
<newAxiom>&apos;ABC-type thiamine transporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061501</classIRI>
<classLabel>cyclic-GMP-AMP synthase activity</classLabel>
<deletedAxiom>&apos;cyclic-GMP-AMP synthase activity&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;cyclic-GMP-AMP synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140699</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097410</classIRI>
<classLabel>hippocampal interneuron differentiation</classLabel>
<deletedAxiom>&apos;hippocampal interneuron differentiation&apos; SubClassOf &apos;forebrain neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;hippocampal interneuron differentiation&apos; SubClassOf &apos;cerebral cortex neuron differentiation&apos;</deletedAxiom>
<newAxiom>&apos;hippocampal interneuron differentiation&apos; SubClassOf &apos;neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097432</classIRI>
<classLabel>hippocampal pyramidal neuron differentiation</classLabel>
<deletedAxiom>&apos;hippocampal pyramidal neuron differentiation&apos; SubClassOf &apos;forebrain neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;hippocampal pyramidal neuron differentiation&apos; SubClassOf &apos;cerebral cortex neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036245</classIRI>
<classLabel>cellular response to menadione</classLabel>
<deletedAxiom>&apos;cellular response to menadione&apos; SubClassOf &apos;cellular response to ketone&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to menadione&apos; SubClassOf &apos;cellular response to vitamin K&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036264</classIRI>
<classLabel>dopamine monooxygenase activity</classLabel>
<deletedAxiom>&apos;dopamine monooxygenase activity&apos; SubClassOf &apos;catechol oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036263</classIRI>
<classLabel>L-DOPA monooxygenase activity</classLabel>
<deletedAxiom>&apos;L-DOPA monooxygenase activity&apos; SubClassOf &apos;catechol oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000220</classIRI>
<classLabel>vacuolar proton-transporting V-type ATPase, V0 domain</classLabel>
<deletedAxiom>&apos;vacuolar proton-transporting V-type ATPase, V0 domain&apos; EquivalentTo &apos;proton-transporting V-type ATPase, V0 domain&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;vacuole&apos;)</deletedAxiom>
<deletedAxiom>&apos;vacuolar proton-transporting V-type ATPase, V0 domain&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;vacuole&apos;</deletedAxiom>
<newAxiom>&apos;vacuolar proton-transporting V-type ATPase, V0 domain&apos; EquivalentTo &apos;proton-transporting V-type ATPase, V0 domain&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;vacuolar membrane&apos;)</newAxiom>
<newAxiom>&apos;vacuolar proton-transporting V-type ATPase, V0 domain&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;vacuolar proton-transporting V-type ATPase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061187</classIRI>
<classLabel>regulation of ribosomal DNA heterochromatin assembly</classLabel>
<newAxiom>&apos;regulation of ribosomal DNA heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061188</classIRI>
<classLabel>negative regulation of ribosomal DNA heterochromatin assembly</classLabel>
<newAxiom>&apos;negative regulation of ribosomal DNA heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin assembly or disassembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000183</classIRI>
<classLabel>rDNA heterochromatin assembly</classLabel>
<newAxiom>&apos;rDNA heterochromatin assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048096</classIRI>
<classLabel>chromatin-mediated maintenance of transcription</classLabel>
<deletedAxiom>&apos;chromatin-mediated maintenance of transcription&apos; SubClassOf &apos;chromatin organization involved in regulation of transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048097</classIRI>
<classLabel>long-term maintenance of gene activation</classLabel>
<deletedAxiom>&apos;long-term maintenance of gene activation&apos; SubClassOf &apos;positive regulation of gene expression, epigenetic&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085018</classIRI>
<classLabel>maintenance of symbiont-containing vacuole by host</classLabel>
<deletedAxiom>&apos;maintenance of symbiont-containing vacuole by host&apos; SubClassOf &apos;modulation by host of symbiont process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000749</classIRI>
<classLabel>positive regulation of rDNA heterochromatin assembly</classLabel>
<newAxiom>&apos;positive regulation of rDNA heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin assembly or disassembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905886</classIRI>
<classLabel>chromatin remodeling involved in meiosis I</classLabel>
<deletedAxiom>&apos;chromatin remodeling involved in meiosis I&apos; SubClassOf &apos;meiosis I cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin remodeling involved in meiosis I&apos; SubClassOf &apos;chromatin remodeling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075182</classIRI>
<classLabel>negative regulation of symbiont transcription in response to host</classLabel>
<deletedAxiom>&apos;negative regulation of symbiont transcription in response to host&apos; SubClassOf &apos;negative regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of symbiont transcription in response to host&apos; SubClassOf &apos;regulation of transcription in response to host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075181</classIRI>
<classLabel>positive regulation of symbiont transcription in response to host</classLabel>
<deletedAxiom>&apos;positive regulation of symbiont transcription in response to host&apos; SubClassOf &apos;regulation of transcription in response to host&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of symbiont transcription in response to host&apos; SubClassOf &apos;positive regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075180</classIRI>
<classLabel>regulation of transcription in response to host</classLabel>
<deletedAxiom>&apos;regulation of transcription in response to host&apos; SubClassOf &apos;response to host&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription in response to host&apos; SubClassOf &apos;regulation of RNA biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016569</classIRI>
<classLabel>covalent chromatin modification</classLabel>
<deletedAxiom>&apos;covalent chromatin modification&apos; SubClassOf &apos;chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;covalent chromatin modification&apos; SubClassOf &apos;macromolecule modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016570</classIRI>
<classLabel>histone modification</classLabel>
<deletedAxiom>&apos;histone modification&apos; SubClassOf &apos;covalent chromatin modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016458</classIRI>
<classLabel>gene silencing</classLabel>
<deletedAxiom>&apos;gene silencing&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090422</classIRI>
<classLabel>thiamine pyrophosphate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;organic cation transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;azole transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;vitamin transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;sulfur compound transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;quaternary ammonium group transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;thiamine transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031940</classIRI>
<classLabel>positive regulation of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin silencing at telomere&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;chromatin silencing at telomere&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing at telomere&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;chromatin silencing at telomere&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing at telomere&apos; SubClassOf &apos;positive regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing at telomere&apos; SubClassOf &apos;regulation of chromatin silencing at telomere&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031937</classIRI>
<classLabel>positive regulation of chromatin silencing</classLabel>
<deletedAxiom>&apos;positive regulation of chromatin silencing&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chromatin silencing&apos; SubClassOf &apos;positive regulation of chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031936</classIRI>
<classLabel>negative regulation of chromatin silencing</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;negative regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;positive regulation of transcription, DNA-templated&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing&apos; SubClassOf &apos;positive regulation of gene expression, epigenetic&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031939</classIRI>
<classLabel>negative regulation of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;negative regulation of chromatin silencing at telomere&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;chromatin silencing at telomere&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing at telomere&apos; SubClassOf &apos;negative regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing at telomere&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;chromatin silencing at telomere&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chromatin silencing at telomere&apos; SubClassOf &apos;regulation of chromatin silencing at telomere&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031938</classIRI>
<classLabel>regulation of chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing at telomere&apos; SubClassOf &apos;regulation of chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing at telomere&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin silencing at telomere&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing at telomere&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin silencing at telomere&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031935</classIRI>
<classLabel>regulation of chromatin silencing</classLabel>
<deletedAxiom>&apos;regulation of chromatin silencing&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing&apos; SubClassOf &apos;regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing&apos; SubClassOf &apos;regulation of gene silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of chromatin silencing&apos; SubClassOf &apos;regulation of transcription, DNA-templated&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090310</classIRI>
<classLabel>negative regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;negative regulation of macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090309</classIRI>
<classLabel>positive regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;positive regulation of macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090308</classIRI>
<classLabel>regulation of DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;regulation of macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090180</classIRI>
<classLabel>positive regulation of thiamine biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of thiamine biosynthetic process&apos; SubClassOf &apos;positive regulation of alcohol biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006772</classIRI>
<classLabel>thiamine metabolic process</classLabel>
<newAxiom>&apos;thiamine metabolic process&apos; SubClassOf &apos;primary alcohol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090053</classIRI>
<classLabel>positive regulation of pericentric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin assembly or disassembly&apos;</newAxiom>
<newAxiom>&apos;positive regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090052</classIRI>
<classLabel>regulation of pericentric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
<newAxiom>&apos;regulation of pericentric heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004097</classIRI>
<classLabel>catechol oxidase activity</classLabel>
<newAxiom>&apos;catechol oxidase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031508</classIRI>
<classLabel>pericentric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;pericentric heterochromatin assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;pericentric heterochromatin assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031507</classIRI>
<classLabel>heterochromatin assembly</classLabel>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromatin organization involved in negative regulation of transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromatin remodeling&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromatin organization involved in negative regulation of transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;chromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;negative regulation of gene expression, epigenetic&apos;</newAxiom>
<newAxiom>&apos;heterochromatin assembly&apos; SubClassOf &apos;gene silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031509</classIRI>
<classLabel>subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;subtelomeric heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf &apos;telomere assembly&apos;</deletedAxiom>
<newAxiom>&apos;subtelomeric heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;chromosome, telomeric region&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102316</classIRI>
<classLabel>L-dopa oxidase activity</classLabel>
<deletedAxiom>&apos;L-dopa oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031418</classIRI>
<classLabel>L-ascorbic acid binding</classLabel>
<newAxiom>&apos;L-ascorbic acid binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
<newAxiom>&apos;L-ascorbic acid binding&apos; SubClassOf &apos;organic cyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031445</classIRI>
<classLabel>regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of chromosome organization&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heterochromatin assembly&apos; SubClassOf &apos;regulation of gene silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031452</classIRI>
<classLabel>negative regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromatin assembly or disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of chromosome organization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of gene silencing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031454</classIRI>
<classLabel>regulation of extent of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031453</classIRI>
<classLabel>positive regulation of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of chromatin assembly or disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006342</classIRI>
<classLabel>chromatin silencing</classLabel>
<deletedAxiom>&apos;chromatin silencing&apos; SubClassOf &apos;negative regulation of gene expression, epigenetic&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing&apos; SubClassOf &apos;gene silencing&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing&apos; SubClassOf &apos;negative regulation of transcription, DNA-templated&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing&apos; SubClassOf &apos;chromatin organization involved in negative regulation of transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006346</classIRI>
<classLabel>DNA methylation-dependent heterochromatin assembly</classLabel>
<deletedAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;DNA methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; SubClassOf &apos;covalent chromatin modification&apos;</deletedAxiom>
<newAxiom>&apos;DNA methylation-dependent heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;DNA-methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006348</classIRI>
<classLabel>chromatin silencing at telomere</classLabel>
<deletedAxiom>&apos;chromatin silencing at telomere&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;chromosome, telomeric region&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at telomere&apos; EquivalentTo &apos;chromatin silencing&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;chromosome, telomeric region&apos;)</deletedAxiom>
<deletedAxiom>&apos;chromatin silencing at telomere&apos; SubClassOf &apos;chromatin silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070868</classIRI>
<classLabel>heterochromatin organization involved in chromatin silencing</classLabel>
<deletedAxiom>&apos;heterochromatin organization involved in chromatin silencing&apos; SubClassOf &apos;chromatin organization involved in negative regulation of transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin organization involved in chromatin silencing&apos; EquivalentTo &apos;heterochromatin organization&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromatin silencing&apos;)</deletedAxiom>
<deletedAxiom>&apos;heterochromatin organization involved in chromatin silencing&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin organization involved in chromatin silencing&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromatin silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021859</classIRI>
<classLabel>pyramidal neuron differentiation</classLabel>
<deletedAxiom>&apos;pyramidal neuron differentiation&apos; SubClassOf &apos;central nervous system neuron differentiation&apos;</deletedAxiom>
<newAxiom>&apos;pyramidal neuron differentiation&apos; SubClassOf &apos;neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021891</classIRI>
<classLabel>olfactory bulb interneuron development</classLabel>
<deletedAxiom>&apos;olfactory bulb interneuron development&apos; SubClassOf &apos;forebrain neuron development&apos;</deletedAxiom>
<newAxiom>&apos;olfactory bulb interneuron development&apos; SubClassOf &apos;neuron development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021889</classIRI>
<classLabel>olfactory bulb interneuron differentiation</classLabel>
<deletedAxiom>&apos;olfactory bulb interneuron differentiation&apos; SubClassOf &apos;forebrain neuron differentiation&apos;</deletedAxiom>
<newAxiom>&apos;olfactory bulb interneuron differentiation&apos; SubClassOf &apos;neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070827</classIRI>
<classLabel>chromatin maintenance</classLabel>
<deletedAxiom>&apos;chromatin maintenance&apos; SubClassOf &apos;cellular component maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin maintenance&apos; SubClassOf &apos;chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070829</classIRI>
<classLabel>heterochromatin maintenance</classLabel>
<deletedAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;chromatin maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;chromosome organization&apos;</deletedAxiom>
<deletedAxiom>&apos;heterochromatin maintenance&apos; SubClassOf &apos;heterochromatin organization involved in chromatin silencing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043156</classIRI>
<classLabel>chromatin remodeling in response to cation stress</classLabel>
<deletedAxiom>&apos;chromatin remodeling in response to cation stress&apos; SubClassOf &apos;chromatin remodeling&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin remodeling in response to cation stress&apos; SubClassOf &apos;cellular response to cation stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080188</classIRI>
<classLabel>gene silencing by RNA-directed DNA methylation</classLabel>
<deletedAxiom>&apos;gene silencing by RNA-directed DNA methylation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;DNA methylation&apos;</deletedAxiom>
<newAxiom>&apos;gene silencing by RNA-directed DNA methylation&apos; SubClassOf &apos;DNA methylation-dependent heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033697</classIRI>
<classLabel>positive regulation of extent of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;regulation of extent of heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033696</classIRI>
<classLabel>negative regulation of extent of heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;regulation of extent of heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of extent of heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heterochromatin assembly&apos;</newAxiom>
<newAxiom>&apos;negative regulation of extent of heterochromatin assembly&apos; SubClassOf &apos;heterochromatin organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070624</classIRI>
<classLabel>negative regulation of thiamine biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of thiamine biosynthetic process&apos; SubClassOf &apos;negative regulation of alcohol biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070623</classIRI>
<classLabel>regulation of thiamine biosynthetic process</classLabel>
<newAxiom>&apos;regulation of thiamine biosynthetic process&apos; SubClassOf &apos;regulation of alcohol biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031056</classIRI>
<classLabel>regulation of histone modification</classLabel>
<deletedAxiom>&apos;regulation of histone modification&apos; SubClassOf &apos;regulation of chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031058</classIRI>
<classLabel>positive regulation of histone modification</classLabel>
<deletedAxiom>&apos;positive regulation of histone modification&apos; SubClassOf &apos;positive regulation of chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031057</classIRI>
<classLabel>negative regulation of histone modification</classLabel>
<deletedAxiom>&apos;negative regulation of histone modification&apos; SubClassOf &apos;negative regulation of chromatin organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033591</classIRI>
<classLabel>response to L-ascorbic acid</classLabel>
<newAxiom>&apos;response to L-ascorbic acid&apos; SubClassOf &apos;response to organic cyclic compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033590</classIRI>
<classLabel>response to cobalamin</classLabel>
<newAxiom>&apos;response to cobalamin&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035986</classIRI>
<classLabel>senescence-associated heterochromatin focus assembly</classLabel>
<deletedAxiom>&apos;senescence-associated heterochromatin focus assembly&apos; SubClassOf &apos;heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060968</classIRI>
<classLabel>regulation of gene silencing</classLabel>
<deletedAxiom>&apos;regulation of gene silencing&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060969</classIRI>
<classLabel>negative regulation of gene silencing</classLabel>
<deletedAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gene silencing&apos; SubClassOf &apos;negative regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060821</classIRI>
<classLabel>inactivation of X chromosome by DNA methylation</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by DNA methylation&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033274</classIRI>
<classLabel>response to vitamin B2</classLabel>
<newAxiom>&apos;response to vitamin B2&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106310</classIRI>
<classLabel>protein serine kinase activity</classLabel>
<deletedAxiom>&apos;protein serine kinase activity&apos; SubClassOf &apos;protein serine/threonine kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein serine kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106311</classIRI>
<classLabel>protein threonine kinase activity</classLabel>
<deletedAxiom>&apos;protein threonine kinase activity&apos; SubClassOf &apos;protein serine/threonine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106264</classIRI>
<classLabel>protein serine kinase activity (using GTP as donor)</classLabel>
<deletedAxiom>&apos;protein serine kinase activity (using GTP as donor)&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein serine kinase activity (using GTP as donor)&apos; SubClassOf &apos;protein serine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060148</classIRI>
<classLabel>positive regulation of posttranscriptional gene silencing</classLabel>
<deletedAxiom>&apos;positive regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of posttranscriptional gene silencing&apos; SubClassOf &apos;positive regulation of biological process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098749</classIRI>
<classLabel>cerebellar neuron development</classLabel>
<deletedAxiom>&apos;cerebellar neuron development&apos; SubClassOf &apos;central nervous system neuron development&apos;</deletedAxiom>
<newAxiom>&apos;cerebellar neuron development&apos; SubClassOf &apos;neuron development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098546</classIRI>
<classLabel>2&apos;,5-3&apos;,5&apos;-cyclic GMP-AMP binding</classLabel>
<deletedAxiom>&apos;2&apos;,5-3&apos;,5&apos;-cyclic GMP-AMP binding&apos; SubClassOf &apos;guanyl ribonucleotide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;2&apos;,5-3&apos;,5&apos;-cyclic GMP-AMP binding&apos; SubClassOf &apos;adenyl ribonucleotide binding&apos;</deletedAxiom>
<deletedAxiom>&apos;2&apos;,5-3&apos;,5&apos;-cyclic GMP-AMP binding&apos; SubClassOf &apos;anion binding&apos;</deletedAxiom>
<deletedAxiom>&apos;2&apos;,5-3&apos;,5&apos;-cyclic GMP-AMP binding&apos; SubClassOf &apos;cyclic nucleotide binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905548</classIRI>
<classLabel>negative regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;subtelomeric heterochromatin assembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;subtelomeric heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of subtelomeric heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;negative regulation of heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905549</classIRI>
<classLabel>positive regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;positive regulation of heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;subtelomeric heterochromatin assembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of subtelomeric heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of subtelomeric heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;subtelomeric heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905547</classIRI>
<classLabel>regulation of subtelomeric heterochromatin assembly</classLabel>
<deletedAxiom>&apos;regulation of subtelomeric heterochromatin assembly&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;subtelomeric heterochromatin assembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of subtelomeric heterochromatin assembly&apos; SubClassOf &apos;regulation of heterochromatin assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of subtelomeric heterochromatin assembly&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;subtelomeric heterochromatin assembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015888</classIRI>
<classLabel>thiamine transport</classLabel>
<deletedAxiom>&apos;thiamine transport&apos; SubClassOf &apos;organic substance transport&apos;</deletedAxiom>
<newAxiom>&apos;thiamine transport&apos; SubClassOf &apos;organic cation transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904481</classIRI>
<classLabel>response to tetrahydrofolate</classLabel>
<deletedAxiom>&apos;response to tetrahydrofolate&apos; SubClassOf &apos;response to organic substance&apos;</deletedAxiom>
<newAxiom>&apos;response to tetrahydrofolate&apos; SubClassOf &apos;response to organonitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904482</classIRI>
<classLabel>cellular response to tetrahydrofolate</classLabel>
<newAxiom>&apos;cellular response to tetrahydrofolate&apos; SubClassOf &apos;cellular response to organonitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030974</classIRI>
<classLabel>thiamine pyrophosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;organic cation transport&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;sulfur compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;pyrimidine-containing compound transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;azole transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;thiamine transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;quaternary ammonium group transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030975</classIRI>
<classLabel>thiamine binding</classLabel>
<newAxiom>&apos;thiamine binding&apos; SubClassOf &apos;cation binding&apos;</newAxiom>
<newAxiom>&apos;thiamine binding&apos; SubClassOf &apos;alcohol binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030976</classIRI>
<classLabel>thiamine pyrophosphate binding</classLabel>
<newAxiom>&apos;thiamine pyrophosphate binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904948</classIRI>
<classLabel>midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;central nervous system neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015234</classIRI>
<classLabel>thiamine transmembrane transporter activity</classLabel>
<newAxiom>&apos;thiamine transmembrane transporter activity&apos; SubClassOf &apos;organic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042572</classIRI>
<classLabel>retinol metabolic process</classLabel>
<newAxiom>&apos;retinol metabolic process&apos; SubClassOf &apos;olefinic compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902795</classIRI>
<classLabel>heterochromatin domain assembly</classLabel>
<newAxiom>&apos;heterochromatin domain assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902794</classIRI>
<classLabel>heterochromatin island assembly</classLabel>
<newAxiom>&apos;heterochromatin island assembly&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902801</classIRI>
<classLabel>regulation of heterochromatin island assembly</classLabel>
<newAxiom>&apos;regulation of heterochromatin island assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902802</classIRI>
<classLabel>regulation of heterochromatin domain assembly</classLabel>
<newAxiom>&apos;regulation of heterochromatin domain assembly&apos; SubClassOf &apos;regulation of chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902860</classIRI>
<classLabel>propionyl-CoA biosynthetic process</classLabel>
<newAxiom>&apos;propionyl-CoA biosynthetic process&apos; SubClassOf &apos;lipid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902858</classIRI>
<classLabel>propionyl-CoA metabolic process</classLabel>
<newAxiom>&apos;propionyl-CoA metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902859</classIRI>
<classLabel>propionyl-CoA catabolic process</classLabel>
<newAxiom>&apos;propionyl-CoA catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019950</classIRI>
<classLabel>SMT3-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;SMT3-dependent protein catabolic process&apos; SubClassOf &apos;modification-dependent protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019951</classIRI>
<classLabel>Smt3-protein conjugation</classLabel>
<deletedAxiom>&apos;Smt3-protein conjugation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;SMT3-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;Smt3-protein conjugation&apos; SubClassOf &apos;protein modification by small protein conjugation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042358</classIRI>
<classLabel>thiamine diphosphate catabolic process</classLabel>
<deletedAxiom>&apos;thiamine diphosphate catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate catabolic process&apos; SubClassOf &apos;aromatic compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate catabolic process&apos; SubClassOf &apos;pyrimidine-containing compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;thiamine diphosphate catabolic process&apos; SubClassOf &apos;thiamine-containing compound catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042357</classIRI>
<classLabel>thiamine diphosphate metabolic process</classLabel>
<deletedAxiom>&apos;thiamine diphosphate metabolic process&apos; SubClassOf &apos;pyrimidine-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate metabolic process&apos; SubClassOf &apos;cellular aromatic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;thiamine diphosphate metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;thiamine diphosphate metabolic process&apos; SubClassOf &apos;thiamine-containing compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042377</classIRI>
<classLabel>vitamin K catabolic process</classLabel>
<newAxiom>&apos;vitamin K catabolic process&apos; SubClassOf &apos;quinone catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042376</classIRI>
<classLabel>phylloquinone catabolic process</classLabel>
<deletedAxiom>&apos;phylloquinone catabolic process&apos; SubClassOf &apos;quinone catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phylloquinone catabolic process&apos; SubClassOf &apos;vitamin K catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042374</classIRI>
<classLabel>phylloquinone metabolic process</classLabel>
<deletedAxiom>&apos;phylloquinone metabolic process&apos; SubClassOf &apos;quinone metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phylloquinone metabolic process&apos; SubClassOf &apos;vitamin K metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042373</classIRI>
<classLabel>vitamin K metabolic process</classLabel>
<newAxiom>&apos;vitamin K metabolic process&apos; SubClassOf &apos;quinone metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042372</classIRI>
<classLabel>phylloquinone biosynthetic process</classLabel>
<deletedAxiom>&apos;phylloquinone biosynthetic process&apos; SubClassOf &apos;quinone biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;phylloquinone biosynthetic process&apos; SubClassOf &apos;vitamin K biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042371</classIRI>
<classLabel>vitamin K biosynthetic process</classLabel>
<newAxiom>&apos;vitamin K biosynthetic process&apos; SubClassOf &apos;quinone biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019852</classIRI>
<classLabel>L-ascorbic acid metabolic process</classLabel>
<newAxiom>&apos;L-ascorbic acid metabolic process&apos; SubClassOf &apos;lactone metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019853</classIRI>
<classLabel>L-ascorbic acid biosynthetic process</classLabel>
<newAxiom>&apos;L-ascorbic acid biosynthetic process&apos; SubClassOf &apos;lactone biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019854</classIRI>
<classLabel>L-ascorbic acid catabolic process</classLabel>
<newAxiom>&apos;L-ascorbic acid catabolic process&apos; SubClassOf &apos;lactone catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140673</classIRI>
<classLabel>chromatin maintenance during transcription elongation</classLabel>
<deletedAxiom>&apos;chromatin maintenance during transcription elongation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transcription elongation from RNA polymerase II promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;chromatin maintenance during transcription elongation&apos; SubClassOf &apos;chromatin maintenance&apos;</deletedAxiom>
<newAxiom>&apos;chromatin maintenance during transcription elongation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transcription by RNA polymerase II&apos;</newAxiom>
<newAxiom>&apos;chromatin maintenance during transcription elongation&apos; SubClassOf &apos;chromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140458</classIRI>
<classLabel>pre-transcriptional gene silencing by RNA</classLabel>
<newAxiom>&apos;pre-transcriptional gene silencing by RNA&apos; SubClassOf &apos;heterochromatin assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140461</classIRI>
<classLabel>subtelomeric heterochromatin organization</classLabel>
<deletedAxiom>&apos;subtelomeric heterochromatin organization&apos; SubClassOf &apos;heterochromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;subtelomeric heterochromatin organization&apos; SubClassOf &apos;telomere organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032572</classIRI>
<classLabel>response to menaquinone</classLabel>
<deletedAxiom>&apos;response to menaquinone&apos; SubClassOf &apos;response to ketone&apos;</deletedAxiom>
<newAxiom>&apos;response to menaquinone&apos; SubClassOf &apos;response to vitamin K&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032571</classIRI>
<classLabel>response to vitamin K</classLabel>
<newAxiom>&apos;response to vitamin K&apos; SubClassOf &apos;response to ketone&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032573</classIRI>
<classLabel>response to phylloquinone</classLabel>
<deletedAxiom>&apos;response to phylloquinone&apos; SubClassOf &apos;response to ketone&apos;</deletedAxiom>
<newAxiom>&apos;response to phylloquinone&apos; SubClassOf &apos;response to vitamin K&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071934</classIRI>
<classLabel>thiamine transmembrane transport</classLabel>
<newAxiom>&apos;thiamine transmembrane transport&apos; SubClassOf &apos;cation transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140142</classIRI>
<classLabel>nucleocytoplasmic carrier activity</classLabel>
<deletedAxiom>&apos;nucleocytoplasmic carrier activity&apos; SubClassOf &apos;protein carrier activity&apos;</deletedAxiom>
<newAxiom>&apos;nucleocytoplasmic carrier activity&apos; SubClassOf &apos;molecular carrier activity&apos;</newAxiom>
<newAxiom>&apos;nucleocytoplasmic carrier activity&apos; EquivalentTo &apos;molecular carrier activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nucleocytoplasmic transport&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140706</classIRI>
<classLabel>protein-containing complex localization to centriolar satellite</classLabel>
<newAxiom>'protein-containing complex localization to centriolar satellite' SubClassOf 'cellular protein-containing complex localization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140704</classIRI>
<classLabel>3',2'-cyclic GMP-AMP binding</classLabel>
<newAxiom>'3',2'-cyclic GMP-AMP binding' SubClassOf 'cyclic nucleotide binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140703</classIRI>
<classLabel>3',3'-cyclic GMP-AMP binding</classLabel>
<newAxiom>'3',3'-cyclic GMP-AMP binding' SubClassOf 'cyclic nucleotide binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140702</classIRI>
<classLabel>cyclic GMP-AMP binding</classLabel>
<newAxiom>'cyclic GMP-AMP binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'cyclic GMP-AMP binding' SubClassOf 'adenyl ribonucleotide binding'</newAxiom>
<newAxiom>'cyclic GMP-AMP binding' SubClassOf 'cyclic nucleotide binding'</newAxiom>
<newAxiom>'cyclic GMP-AMP binding' SubClassOf 'guanyl ribonucleotide binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140701</classIRI>
<classLabel>3',3'-cyclic GMP-AMP synthase activity</classLabel>
<newAxiom>'3',3'-cyclic GMP-AMP synthase activity' SubClassOf 'cyclic GMP-AMP synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140700</classIRI>
<classLabel>3',2'-cyclic GMP-AMP synthase activity</classLabel>
<newAxiom>'3',2'-cyclic GMP-AMP synthase activity' SubClassOf 'cyclic GMP-AMP synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140699</classIRI>
<classLabel>cyclic GMP-AMP synthase activity</classLabel>
<newAxiom>'cyclic GMP-AMP synthase activity' SubClassOf 'nucleotidyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140698</classIRI>
<classLabel>attachment of telomeric heterochromatin to nuclear envelope</classLabel>
<newAxiom>'attachment of telomeric heterochromatin to nuclear envelope' SubClassOf 'chromosome attachment to the nuclear envelope'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036264</classIRI>
<classLabel>dopamine monooxygenase activity</classLabel>
<newAxiom>'dopamine monooxygenase activity' SubClassOf 'catechol oxidase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036263</classIRI>
<classLabel>L-DOPA monooxygenase activity</classLabel>
<newAxiom>'L-DOPA monooxygenase activity' SubClassOf 'catechol oxidase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102316</classIRI>
<classLabel>L-dopa oxidase activity</classLabel>
<newAxiom>'L-dopa oxidase activity' SubClassOf 'oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031454</classIRI>
<classLabel>regulation of extent of heterochromatin assembly</classLabel>
<newAxiom>'regulation of extent of heterochromatin assembly' SubClassOf 'regulation of heterochromatin assembly'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006342</classIRI>
<classLabel>chromatin silencing</classLabel>
<newAxiom>'chromatin silencing' SubClassOf 'negative regulation of gene expression, epigenetic'</newAxiom>
<newAxiom>'chromatin silencing' SubClassOf 'gene silencing'</newAxiom>
<newAxiom>'chromatin silencing' SubClassOf 'negative regulation of transcription, DNA-templated'</newAxiom>
<newAxiom>'chromatin silencing' SubClassOf 'chromatin organization involved in negative regulation of transcription'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006348</classIRI>
<classLabel>chromatin silencing at telomere</classLabel>
<newAxiom>'chromatin silencing at telomere' SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some 'chromosome, telomeric region'</newAxiom>
<newAxiom>'chromatin silencing at telomere' EquivalentTo 'chromatin silencing' and (http://purl.obolibrary.org/obo/BFO_0000066 some 'chromosome, telomeric region')</newAxiom>
<newAxiom>'chromatin silencing at telomere' SubClassOf 'chromatin silencing'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106311</classIRI>
<classLabel>protein threonine kinase activity</classLabel>
<newAxiom>'protein threonine kinase activity' SubClassOf 'protein serine/threonine kinase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098546</classIRI>
<classLabel>2',5-3',5'-cyclic GMP-AMP binding</classLabel>
<newAxiom>'2',5-3',5'-cyclic GMP-AMP binding' SubClassOf 'guanyl ribonucleotide binding'</newAxiom>
<newAxiom>'2',5-3',5'-cyclic GMP-AMP binding' SubClassOf 'adenyl ribonucleotide binding'</newAxiom>
<newAxiom>'2',5-3',5'-cyclic GMP-AMP binding' SubClassOf 'anion binding'</newAxiom>
<newAxiom>'2',5-3',5'-cyclic GMP-AMP binding' SubClassOf 'cyclic nucleotide binding'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019951</classIRI>
<classLabel>Smt3-protein conjugation</classLabel>
<newAxiom>'Smt3-protein conjugation' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'SMT3-dependent protein catabolic process'</newAxiom>
<newAxiom>'Smt3-protein conjugation' SubClassOf 'protein modification by small protein conjugation'</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>