<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
240
</numberChangedClasses>
<numberNewClasses>
37
</numberNewClasses>
<numberDeletedClasses>
11
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103073</classIRI>
<classLabel>anandamide amidohydrolase activity</classLabel>
<deletedAxiom>&apos;anandamide amidohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009815</classIRI>
<classLabel>1-aminocyclopropane-1-carboxylate oxidase activity</classLabel>
<deletedAxiom>&apos;1-aminocyclopropane-1-carboxylate oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;1-aminocyclopropane-1-carboxylate oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022821</classIRI>
<classLabel>potassium ion antiporter activity</classLabel>
<deletedAxiom>&apos;potassium ion antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;potassium ion antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;potassium ion antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140828</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103023</classIRI>
<classLabel>ITPase activity</classLabel>
<deletedAxiom>&apos;ITPase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;ITPase activity&apos; SubClassOf &apos;nucleoside-triphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010735</classIRI>
<classLabel>positive regulation of transcription via serum response element binding</classLabel>
<deletedAxiom>&apos;positive regulation of transcription via serum response element binding&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009758</classIRI>
<classLabel>carbohydrate utilization</classLabel>
<deletedAxiom>&apos;carbohydrate utilization&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<deletedAxiom>&apos;carbohydrate utilization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;detection of carbohydrate stimulus&apos;</deletedAxiom>
<newAxiom>&apos;carbohydrate utilization&apos; SubClassOf &apos;response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046737</classIRI>
<classLabel>induction of cell-mediated immune response in host by virus</classLabel>
<deletedAxiom>&apos;induction of cell-mediated immune response in host by virus&apos; SubClassOf &apos;induction by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046736</classIRI>
<classLabel>induction of humoral immune response in host by virus</classLabel>
<deletedAxiom>&apos;induction of humoral immune response in host by virus&apos; SubClassOf &apos;induction by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046738</classIRI>
<classLabel>induction of innate immune response in host by virus</classLabel>
<deletedAxiom>&apos;induction of innate immune response in host by virus&apos; SubClassOf &apos;induction by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046730</classIRI>
<classLabel>induction by virus of host immune response</classLabel>
<deletedAxiom>&apos;induction by virus of host immune response&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;immune response&apos;)</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host immune response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host immune response&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host immune response&apos; SubClassOf &apos;modulation by virus of host immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host immune response&apos; SubClassOf &apos;positive regulation of immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host immune response&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044022</classIRI>
<classLabel>histone kinase activity (H3-S28 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-S28 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-S28 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044023</classIRI>
<classLabel>histone kinase activity (H4-S1 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H4-S1 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H4-S1 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044024</classIRI>
<classLabel>histone kinase activity (H2A-S1 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H2A-S1 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H2A-S1 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044025</classIRI>
<classLabel>histone kinase activity (H2B-S14 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H2B-S14 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H2B-S14 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019098</classIRI>
<classLabel>reproductive behavior</classLabel>
<deletedAxiom>&apos;reproductive behavior&apos; EquivalentTo &apos;behavior&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;reproduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;reproductive behavior&apos; SubClassOf &apos;multicellular organismal reproductive process&apos;</deletedAxiom>
<newAxiom>&apos;reproductive behavior&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;multicellular organism reproduction&apos;</newAxiom>
<newAxiom>&apos;reproductive behavior&apos; SubClassOf &apos;reproductive process&apos;</newAxiom>
<newAxiom>&apos;reproductive behavior&apos; EquivalentTo &apos;behavior&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;multicellular organism reproduction&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034556</classIRI>
<classLabel>nitrobenzoate nitroreductase activity</classLabel>
<deletedAxiom>&apos;nitrobenzoate nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;nitrobenzoate nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046403</classIRI>
<classLabel>polynucleotide 3&apos;-phosphatase activity</classLabel>
<deletedAxiom>&apos;polynucleotide 3&apos;-phosphatase activity&apos; SubClassOf &apos;polynucleotide phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;polynucleotide 3&apos;-phosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;polynucleotide 3&apos; dephosphorylation&apos;</deletedAxiom>
<newAxiom>&apos;polynucleotide 3&apos;-phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034418</classIRI>
<classLabel>urate biosynthetic process</classLabel>
<deletedAxiom>&apos;urate biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;urate biosynthetic process&apos; SubClassOf &apos;purine-containing compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046415</classIRI>
<classLabel>urate metabolic process</classLabel>
<deletedAxiom>&apos;urate metabolic process&apos; SubClassOf &apos;organic acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;urate metabolic process&apos; SubClassOf &apos;purine-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;urate metabolic process&apos; SubClassOf &apos;small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034431</classIRI>
<classLabel>bis(5&apos;-adenosyl)-hexaphosphatase activity</classLabel>
<deletedAxiom>&apos;bis(5&apos;-adenosyl)-hexaphosphatase activity&apos; SubClassOf &apos;nucleotide diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;bis(5&apos;-adenosyl)-hexaphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034432</classIRI>
<classLabel>bis(5&apos;-adenosyl)-pentaphosphatase activity</classLabel>
<deletedAxiom>&apos;bis(5&apos;-adenosyl)-pentaphosphatase activity&apos; SubClassOf &apos;nucleotide diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;bis(5&apos;-adenosyl)-pentaphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034246</classIRI>
<classLabel>mitochondrial transcription factor activity</classLabel>
<deletedAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;DNA-binding transcription factor activity&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;transcription regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010292</classIRI>
<classLabel>GTP:GDP antiporter activity</classLabel>
<deletedAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;GTP:GDP antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061866</classIRI>
<classLabel>negative regulation of histone H3-S10 phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-S10 phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-S10 phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-S10 phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-S10 phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-S10 phosphorylation&apos; SubClassOf &apos;negative regulation of histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-S10 phosphorylation&apos; SubClassOf &apos;negative regulation of peptidyl-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061768</classIRI>
<classLabel>magnesium:sodium antiporter activity</classLabel>
<deletedAxiom>&apos;magnesium:sodium antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;magnesium:sodium antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140828</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061697</classIRI>
<classLabel>protein-glutaryllysine deglutarylase activity</classLabel>
<deletedAxiom>&apos;protein-glutaryllysine deglutarylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;peptidyl-lysine deglutarylation&apos;</deletedAxiom>
<newAxiom>&apos;protein-glutaryllysine deglutarylase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000281</classIRI>
<classLabel>regulation of histone H3-T3 phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation&apos; SubClassOf &apos;regulation of peptidyl-threonine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-T3 phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation&apos; SubClassOf &apos;regulation of histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-T3 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000514</classIRI>
<classLabel>3-sulfino-L-alanine: proton, glutamate antiporter activity</classLabel>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000515</classIRI>
<classLabel>aspartate:glutamate, proton antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036422</classIRI>
<classLabel>heptaprenyl diphosphate synthase activity</classLabel>
<deletedAxiom>&apos;heptaprenyl diphosphate synthase activity&apos; SubClassOf &apos;prenyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061426</classIRI>
<classLabel>positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;sulfite transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of sulfite transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061423</classIRI>
<classLabel>positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of sodium ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;sodium ion transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097301</classIRI>
<classLabel>regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;cellular potassium ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097382</classIRI>
<classLabel>deoxynucleoside-diphosphatase activity</classLabel>
<deletedAxiom>&apos;deoxynucleoside-diphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097383</classIRI>
<classLabel>dIDP diphosphatase activity</classLabel>
<deletedAxiom>&apos;dIDP diphosphatase activity&apos; SubClassOf &apos;deoxynucleoside-diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;dIDP diphosphatase activity&apos; SubClassOf &apos;nucleoside-diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051920</classIRI>
<classLabel>peroxiredoxin activity</classLabel>
<deletedAxiom>&apos;peroxiredoxin activity&apos; SubClassOf &apos;oxidoreductase activity, acting on peroxide as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxiredoxin activity&apos; SubClassOf &apos;antioxidant activity&apos;</deletedAxiom>
<newAxiom>&apos;peroxiredoxin activity&apos; SubClassOf &apos;peroxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120108</classIRI>
<classLabel>DNA-3&apos;-diphospho-5&apos;-guanosine diphosphatase</classLabel>
<deletedAxiom>&apos;DNA-3&apos;-diphospho-5&apos;-guanosine diphosphatase&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</deletedAxiom>
<newAxiom>&apos;DNA-3&apos;-diphospho-5&apos;-guanosine diphosphatase&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097226</classIRI>
<classLabel>sperm mitochondrial sheath</classLabel>
<deletedAxiom>&apos;sperm mitochondrial sheath&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;sperm flagellum&apos;</deletedAxiom>
<newAxiom>&apos;sperm mitochondrial sheath&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;sperm midpiece&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904089</classIRI>
<classLabel>negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;neuron apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of neuron apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990003</classIRI>
<classLabel>inosine-diphosphatase activity</classLabel>
<deletedAxiom>&apos;inosine-diphosphatase activity&apos; SubClassOf &apos;nucleotide phosphatase activity, acting on free nucleotides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061108</classIRI>
<classLabel>seminal vesicle epithelium development</classLabel>
<deletedAxiom>&apos;seminal vesicle epithelium development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;seminal vesicle epithelium development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990164</classIRI>
<classLabel>histone H2A phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A phosphorylation&apos; SubClassOf &apos;histone phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036054</classIRI>
<classLabel>protein-malonyllysine demalonylase activity</classLabel>
<deletedAxiom>&apos;protein-malonyllysine demalonylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;peptidyl-lysine demalonylation&apos;</deletedAxiom>
<newAxiom>&apos;protein-malonyllysine demalonylase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990245</classIRI>
<classLabel>histone H2A-T120 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A-T120 phosphorylation&apos; SubClassOf &apos;histone H2A phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A-T120 phosphorylation&apos; SubClassOf &apos;histone-threonine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990244</classIRI>
<classLabel>histone kinase activity (H2A-T120 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H2A-T120 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H2A-T120 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000817</classIRI>
<classLabel>regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore</classLabel>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; SubClassOf &apos;regulation of histone H3-T3 phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; EquivalentTo &apos;regulation of histone H3-T3 phosphorylation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromosome passenger complex localization to kinetochore&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromosome passenger complex localization to kinetochore&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000751</classIRI>
<classLabel>histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore</classLabel>
<deletedAxiom>&apos;histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; SubClassOf &apos;histone H3-T3 phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromosome passenger complex localization to kinetochore&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore&apos; EquivalentTo &apos;histone H3-T3 phosphorylation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromosome passenger complex localization to kinetochore&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110153</classIRI>
<classLabel>RNA NAD-cap (NMN-forming) hydrolase activity</classLabel>
<deletedAxiom>&apos;RNA NAD-cap (NMN-forming) hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;RNA NAD-cap (NMN-forming) hydrolase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905867</classIRI>
<classLabel>epididymis development</classLabel>
<deletedAxiom>&apos;epididymis development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110081</classIRI>
<classLabel>negative regulation of placenta blood vessel development</classLabel>
<deletedAxiom>&apos;negative regulation of placenta blood vessel development&apos; SubClassOf &apos;negative regulation of reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110080</classIRI>
<classLabel>positive regulation of placenta blood vessel development</classLabel>
<deletedAxiom>&apos;positive regulation of placenta blood vessel development&apos; SubClassOf &apos;positive regulation of reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110079</classIRI>
<classLabel>regulation of placenta blood vessel development</classLabel>
<deletedAxiom>&apos;regulation of placenta blood vessel development&apos; SubClassOf &apos;regulation of reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051139</classIRI>
<classLabel>metal ion:proton antiporter activity</classLabel>
<deletedAxiom>&apos;metal ion:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;metal ion:proton antiporter activity&apos; SubClassOf &apos;metal ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;metal ion:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;metal ion:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;metal ion:proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140828</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004651</classIRI>
<classLabel>polynucleotide 5&apos;-phosphatase activity</classLabel>
<deletedAxiom>&apos;polynucleotide 5&apos;-phosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;polynucleotide 5&apos; dephosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;polynucleotide 5&apos;-phosphatase activity&apos; SubClassOf &apos;polynucleotide phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;polynucleotide 5&apos;-phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004657</classIRI>
<classLabel>proline dehydrogenase activity</classLabel>
<deletedAxiom>&apos;proline dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors&apos;</deletedAxiom>
<newAxiom>&apos;proline dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016572</classIRI>
<classLabel>histone phosphorylation</classLabel>
<deletedAxiom>&apos;histone phosphorylation&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone phosphorylation&apos; SubClassOf &apos;protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903709</classIRI>
<classLabel>uterine gland development</classLabel>
<deletedAxiom>&apos;uterine gland development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043990</classIRI>
<classLabel>histone H2A-S1 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A-S1 phosphorylation&apos; SubClassOf &apos;histone H2A phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A-S1 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043991</classIRI>
<classLabel>histone H2B-S14 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2B-S14 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043987</classIRI>
<classLabel>histone H3-S10 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-S10 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043988</classIRI>
<classLabel>histone H3-S28 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-S28 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043989</classIRI>
<classLabel>histone H4-S1 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H4-S1 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090214</classIRI>
<classLabel>spongiotrophoblast layer developmental growth</classLabel>
<deletedAxiom>&apos;spongiotrophoblast layer developmental growth&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043872</classIRI>
<classLabel>lysine:cadaverine antiporter activity</classLabel>
<deletedAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043861</classIRI>
<classLabel>agmatine:putrescine antiporter activity</classLabel>
<deletedAxiom>&apos;agmatine:putrescine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;agmatine:putrescine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043862</classIRI>
<classLabel>arginine:agmatine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;arginine:agmatine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043858</classIRI>
<classLabel>arginine:ornithine antiporter activity</classLabel>
<deletedAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
<newAxiom>&apos;arginine:ornithine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016275</classIRI>
<classLabel>[cytochrome c]-arginine N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;[cytochrome c]-arginine N-methyltransferase activity&apos; SubClassOf &apos;protein-arginine N-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0100045</classIRI>
<classLabel>negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;arginine catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter&apos; SubClassOf &apos;transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;arginine catabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102668</classIRI>
<classLabel>liquiritigenin,NADPH:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;liquiritigenin,NADPH:oxygen oxidoreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0100026</classIRI>
<classLabel>positive regulation of DNA repair by transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of DNA repair by transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA repair&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA repair by transcription from RNA polymerase II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA repair&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA repair by transcription from RNA polymerase II promoter&apos; SubClassOf &apos;transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006808</classIRI>
<classLabel>regulation of nitrogen utilization</classLabel>
<deletedAxiom>&apos;regulation of nitrogen utilization&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of nitrogen utilization&apos; SubClassOf &apos;regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102604</classIRI>
<classLabel>naringenin,NADPH:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;naringenin,NADPH:oxygen oxidoreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006791</classIRI>
<classLabel>sulfur utilization</classLabel>
<deletedAxiom>&apos;sulfur utilization&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<newAxiom>&apos;sulfur utilization&apos; SubClassOf &apos;response to nutrient levels&apos;</newAxiom>
<newAxiom>&apos;sulfur utilization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sulfur compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006792</classIRI>
<classLabel>regulation of sulfur utilization</classLabel>
<deletedAxiom>&apos;regulation of sulfur utilization&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sulfur utilization&apos; SubClassOf &apos;regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006795</classIRI>
<classLabel>regulation of phosphorus utilization</classLabel>
<deletedAxiom>&apos;regulation of phosphorus utilization&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of phosphorus utilization&apos; SubClassOf &apos;regulation of phosphorus metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006794</classIRI>
<classLabel>phosphorus utilization</classLabel>
<deletedAxiom>&apos;phosphorus utilization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphorus utilization&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<newAxiom>&apos;phosphorus utilization&apos; SubClassOf &apos;phosphorus metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043799</classIRI>
<classLabel>glycine oxidase activity</classLabel>
<deletedAxiom>&apos;glycine oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;glycine oxidase activity&apos; SubClassOf &apos;aliphatic-amine oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102552</classIRI>
<classLabel>lipoyl synthase activity (acting on glycine-cleavage complex H protein</classLabel>
<deletedAxiom>&apos;lipoyl synthase activity (acting on glycine-cleavage complex H protein&apos; SubClassOf &apos;sulfurtransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102553</classIRI>
<classLabel>lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)</classLabel>
<deletedAxiom>&apos;lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)&apos; SubClassOf &apos;sulfurtransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102554</classIRI>
<classLabel>lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein</classLabel>
<deletedAxiom>&apos;lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein&apos; SubClassOf &apos;sulfurtransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043609</classIRI>
<classLabel>regulation of carbon utilization</classLabel>
<deletedAxiom>&apos;regulation of carbon utilization&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of carbon utilization&apos; SubClassOf &apos;regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043610</classIRI>
<classLabel>regulation of carbohydrate utilization</classLabel>
<deletedAxiom>&apos;regulation of carbohydrate utilization&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of carbohydrate utilization&apos; SubClassOf &apos;regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102490</classIRI>
<classLabel>8-oxo-dGTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;8-oxo-dGTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102491</classIRI>
<classLabel>dGTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;dGTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102489</classIRI>
<classLabel>GTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;GTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102485</classIRI>
<classLabel>dATP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;dATP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102486</classIRI>
<classLabel>dCTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;dCTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102487</classIRI>
<classLabel>dUTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;dUTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102488</classIRI>
<classLabel>dTTP phosphohydrolase activity</classLabel>
<deletedAxiom>&apos;dTTP phosphohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102459</classIRI>
<classLabel>8-oxo-deoxyadenine diphosphate phosphatase activity</classLabel>
<deletedAxiom>&apos;8-oxo-deoxyadenine diphosphate phosphatase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;8-oxo-deoxyadenine diphosphate phosphatase activity&apos; SubClassOf &apos;nucleoside-diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018546</classIRI>
<classLabel>nitrobenzene nitroreductase activity</classLabel>
<deletedAxiom>&apos;nitrobenzene nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;nitrobenzene nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043458</classIRI>
<classLabel>ethanol biosynthetic process involved in glucose fermentation to ethanol</classLabel>
<deletedAxiom>&apos;ethanol biosynthetic process involved in glucose fermentation to ethanol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;glycolytic fermentation to ethanol&apos;</deletedAxiom>
<deletedAxiom>&apos;ethanol biosynthetic process involved in glucose fermentation to ethanol&apos; SubClassOf &apos;ethanol biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ethanol biosynthetic process involved in glucose fermentation to ethanol&apos; EquivalentTo &apos;ethanol biosynthetic process&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;glycolytic fermentation to ethanol&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033943</classIRI>
<classLabel>galactan 1,3-beta-galactosidase activity</classLabel>
<deletedAxiom>&apos;galactan 1,3-beta-galactosidase activity&apos; SubClassOf &apos;galactosidase activity&apos;</deletedAxiom>
<newAxiom>&apos;galactan 1,3-beta-galactosidase activity&apos; SubClassOf &apos;beta-galactosidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045942</classIRI>
<classLabel>negative regulation of phosphorus utilization</classLabel>
<deletedAxiom>&apos;negative regulation of phosphorus utilization&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of phosphorus utilization&apos; SubClassOf &apos;negative regulation of phosphorus metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045949</classIRI>
<classLabel>positive regulation of phosphorus utilization</classLabel>
<deletedAxiom>&apos;positive regulation of phosphorus utilization&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of phosphorus utilization&apos; SubClassOf &apos;positive regulation of phosphorus metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070907</classIRI>
<classLabel>histidine:histamine antiporter activity</classLabel>
<deletedAxiom>&apos;histidine:histamine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;histidine:histamine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070906</classIRI>
<classLabel>aspartate:alanine antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;aspartate:alanine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006362</classIRI>
<classLabel>transcription elongation from RNA polymerase I promoter</classLabel>
<deletedAxiom>&apos;transcription elongation from RNA polymerase I promoter&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transcription by RNA polymerase I&apos;</deletedAxiom>
<newAxiom>&apos;transcription elongation from RNA polymerase I promoter&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nucleolar large rRNA transcription by RNA polymerase I&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070909</classIRI>
<classLabel>glutamate:gamma-aminobutyric acid antiporter activity</classLabel>
<deletedAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070908</classIRI>
<classLabel>tyrosine:tyramine antiporter activity</classLabel>
<deletedAxiom>&apos;tyrosine:tyramine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tyrosine:tyramine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102077</classIRI>
<classLabel>oleamide hydrolase activity</classLabel>
<deletedAxiom>&apos;oleamide hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102039</classIRI>
<classLabel>alkylhydroperoxide reductase activity</classLabel>
<deletedAxiom>&apos;alkylhydroperoxide reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;alkylhydroperoxide reductase activity&apos; SubClassOf &apos;peroxiredoxin activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045848</classIRI>
<classLabel>positive regulation of nitrogen utilization</classLabel>
<deletedAxiom>&apos;positive regulation of nitrogen utilization&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of nitrogen utilization&apos; SubClassOf &apos;positive regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045847</classIRI>
<classLabel>negative regulation of nitrogen utilization</classLabel>
<deletedAxiom>&apos;negative regulation of nitrogen utilization&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of nitrogen utilization&apos; SubClassOf &apos;negative regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045882</classIRI>
<classLabel>negative regulation of sulfur utilization</classLabel>
<deletedAxiom>&apos;negative regulation of sulfur utilization&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of sulfur utilization&apos; SubClassOf &apos;negative regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045883</classIRI>
<classLabel>positive regulation of sulfur utilization</classLabel>
<deletedAxiom>&apos;positive regulation of sulfur utilization&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of sulfur utilization&apos; SubClassOf &apos;positive regulation of response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070773</classIRI>
<classLabel>protein-N-terminal glutamine amidohydrolase activity</classLabel>
<newAxiom>&apos;protein-N-terminal glutamine amidohydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008734</classIRI>
<classLabel>L-aspartate oxidase activity</classLabel>
<deletedAxiom>&apos;L-aspartate oxidase activity&apos; SubClassOf &apos;aspartate oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008735</classIRI>
<classLabel>carnitine dehydratase activity</classLabel>
<deletedAxiom>&apos;carnitine dehydratase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<newAxiom>&apos;carnitine dehydratase activity&apos; SubClassOf &apos;CoA-transferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018110</classIRI>
<classLabel>histone arginine kinase activity</classLabel>
<deletedAxiom>&apos;histone arginine kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;peptidyl-arginine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008796</classIRI>
<classLabel>bis(5&apos;-nucleosyl)-tetraphosphatase activity</classLabel>
<deletedAxiom>&apos;bis(5&apos;-nucleosyl)-tetraphosphatase activity&apos; SubClassOf &apos;nucleotide diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;bis(5&apos;-nucleosyl)-tetraphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033739</classIRI>
<classLabel>preQ1 synthase activity</classLabel>
<deletedAxiom>&apos;preQ1 synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;preQ1 synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033770</classIRI>
<classLabel>2-hydroxyisoflavanone synthase activity</classLabel>
<deletedAxiom>&apos;2-hydroxyisoflavanone synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<newAxiom>&apos;2-hydroxyisoflavanone synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008518</classIRI>
<classLabel>folate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;folate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008418</classIRI>
<classLabel>protein-N-terminal asparagine amidohydrolase activity</classLabel>
<newAxiom>&apos;protein-N-terminal asparagine amidohydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008445</classIRI>
<classLabel>D-aspartate oxidase activity</classLabel>
<deletedAxiom>&apos;D-aspartate oxidase activity&apos; SubClassOf &apos;aspartate oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008379</classIRI>
<classLabel>thioredoxin peroxidase activity</classLabel>
<deletedAxiom>&apos;thioredoxin peroxidase activity&apos; SubClassOf &apos;peroxiredoxin activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035978</classIRI>
<classLabel>histone H2A-S139 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A-S139 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A-S139 phosphorylation&apos; SubClassOf &apos;histone H2A phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035979</classIRI>
<classLabel>histone kinase activity (H2A-S139 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H2A-S139 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H2A-S139 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047883</classIRI>
<classLabel>ethanolamine oxidase activity</classLabel>
<deletedAxiom>&apos;ethanolamine oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;ethanolamine oxidase activity&apos; SubClassOf &apos;aliphatic-amine oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035846</classIRI>
<classLabel>oviduct epithelium development</classLabel>
<deletedAxiom>&apos;oviduct epithelium development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;oviduct epithelium development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060710</classIRI>
<classLabel>chorio-allantoic fusion</classLabel>
<deletedAxiom>&apos;chorio-allantoic fusion&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060711</classIRI>
<classLabel>labyrinthine layer development</classLabel>
<deletedAxiom>&apos;labyrinthine layer development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;labyrinthine layer development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060714</classIRI>
<classLabel>labyrinthine layer formation</classLabel>
<deletedAxiom>&apos;labyrinthine layer formation&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060712</classIRI>
<classLabel>spongiotrophoblast layer development</classLabel>
<deletedAxiom>&apos;spongiotrophoblast layer development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060713</classIRI>
<classLabel>labyrinthine layer morphogenesis</classLabel>
<deletedAxiom>&apos;labyrinthine layer morphogenesis&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060716</classIRI>
<classLabel>labyrinthine layer blood vessel development</classLabel>
<deletedAxiom>&apos;labyrinthine layer blood vessel development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033128</classIRI>
<classLabel>negative regulation of histone phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone phosphorylation&apos; SubClassOf &apos;regulation of histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone phosphorylation&apos; SubClassOf &apos;negative regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone phosphorylation&apos; SubClassOf &apos;negative regulation of histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033127</classIRI>
<classLabel>regulation of histone phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of histone phosphorylation&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone phosphorylation&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone phosphorylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033129</classIRI>
<classLabel>positive regulation of histone phosphorylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone phosphorylation&apos; SubClassOf &apos;positive regulation of histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone phosphorylation&apos; SubClassOf &apos;regulation of histone phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone phosphorylation&apos; SubClassOf &apos;positive regulation of protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060722</classIRI>
<classLabel>cell proliferation involved in embryonic placenta development</classLabel>
<deletedAxiom>&apos;cell proliferation involved in embryonic placenta development&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060723</classIRI>
<classLabel>regulation of cell proliferation involved in embryonic placenta development</classLabel>
<deletedAxiom>&apos;regulation of cell proliferation involved in embryonic placenta development&apos; SubClassOf &apos;regulation of reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045119</classIRI>
<classLabel>azole:proton antiporter activity</classLabel>
<deletedAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;azole:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033196</classIRI>
<classLabel>tryparedoxin peroxidase activity</classLabel>
<deletedAxiom>&apos;tryparedoxin peroxidase activity&apos; SubClassOf &apos;peroxiredoxin activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047710</classIRI>
<classLabel>bis(5&apos;-adenosyl)-triphosphatase activity</classLabel>
<deletedAxiom>&apos;bis(5&apos;-adenosyl)-triphosphatase activity&apos; SubClassOf &apos;nucleotide diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;bis(5&apos;-adenosyl)-triphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060670</classIRI>
<classLabel>branching involved in labyrinthine layer morphogenesis</classLabel>
<deletedAxiom>&apos;branching involved in labyrinthine layer morphogenesis&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060669</classIRI>
<classLabel>embryonic placenta morphogenesis</classLabel>
<deletedAxiom>&apos;embryonic placenta morphogenesis&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060673</classIRI>
<classLabel>cell-cell signaling involved in placenta development</classLabel>
<deletedAxiom>&apos;cell-cell signaling involved in placenta development&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060674</classIRI>
<classLabel>placenta blood vessel development</classLabel>
<deletedAxiom>&apos;placenta blood vessel development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106421</classIRI>
<classLabel>L-glutamate:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
<newAxiom>&apos;L-glutamate:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060525</classIRI>
<classLabel>prostate glandular acinus development</classLabel>
<deletedAxiom>&apos;prostate glandular acinus development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;prostate glandular acinus development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
<newAxiom>&apos;prostate glandular acinus development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072541</classIRI>
<classLabel>peroxynitrite reductase activity</classLabel>
<deletedAxiom>&apos;peroxynitrite reductase activity&apos; SubClassOf &apos;peroxiredoxin activity&apos;</deletedAxiom>
<newAxiom>&apos;peroxynitrite reductase activity&apos; SubClassOf &apos;peroxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106378</classIRI>
<classLabel>2-hydroxy-dATP hydrolase activity</classLabel>
<deletedAxiom>&apos;2-hydroxy-dATP hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;2-hydroxy-dATP hydrolase activity&apos; SubClassOf &apos;nucleoside-triphosphate diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106377</classIRI>
<classLabel>2-hydroxy-ATP hydrolase activity</classLabel>
<deletedAxiom>&apos;2-hydroxy-ATP hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;2-hydroxy-ATP hydrolase activity&apos; SubClassOf &apos;nucleoside-triphosphate diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106379</classIRI>
<classLabel>8-oxo-(d)RTP hydrolase activity</classLabel>
<deletedAxiom>&apos;8-oxo-(d)RTP hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;8-oxo-(d)RTP hydrolase activity&apos; SubClassOf &apos;nucleoside-triphosphate diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035406</classIRI>
<classLabel>histone-tyrosine phosphorylation</classLabel>
<deletedAxiom>&apos;histone-tyrosine phosphorylation&apos; SubClassOf &apos;peptidyl-tyrosine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone-tyrosine phosphorylation&apos; SubClassOf &apos;histone phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035407</classIRI>
<classLabel>histone H3-T11 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-T11 phosphorylation&apos; SubClassOf &apos;histone-threonine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035404</classIRI>
<classLabel>histone-serine phosphorylation</classLabel>
<deletedAxiom>&apos;histone-serine phosphorylation&apos; SubClassOf &apos;peptidyl-serine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone-serine phosphorylation&apos; SubClassOf &apos;histone phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035405</classIRI>
<classLabel>histone-threonine phosphorylation</classLabel>
<deletedAxiom>&apos;histone-threonine phosphorylation&apos; SubClassOf &apos;peptidyl-threonine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone-threonine phosphorylation&apos; SubClassOf &apos;histone phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035408</classIRI>
<classLabel>histone H3-T6 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-T6 phosphorylation&apos; SubClassOf &apos;histone-threonine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035409</classIRI>
<classLabel>histone H3-Y41 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-Y41 phosphorylation&apos; SubClassOf &apos;histone-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035402</classIRI>
<classLabel>histone kinase activity (H3-T11 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-T11 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-T11 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035403</classIRI>
<classLabel>histone kinase activity (H3-T6 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-T6 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-T6 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035400</classIRI>
<classLabel>histone tyrosine kinase activity</classLabel>
<deletedAxiom>&apos;histone tyrosine kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone-tyrosine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035401</classIRI>
<classLabel>histone kinase activity (H3-Y41 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-Y41 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-Y41 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072370</classIRI>
<classLabel>histone H2A-S121 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A-S121 phosphorylation&apos; SubClassOf &apos;histone-serine phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A-S121 phosphorylation&apos; SubClassOf &apos;histone H2A phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072371</classIRI>
<classLabel>histone kinase activity (H2A-S121 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H2A-S121 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H2A-S121 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072354</classIRI>
<classLabel>histone kinase activity (H3-T3 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-T3 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-T3 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072355</classIRI>
<classLabel>histone H3-T3 phosphorylation</classLabel>
<deletedAxiom>&apos;histone H3-T3 phosphorylation&apos; SubClassOf &apos;histone-threonine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035184</classIRI>
<classLabel>histone threonine kinase activity</classLabel>
<deletedAxiom>&apos;histone threonine kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone-threonine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001892</classIRI>
<classLabel>embryonic placenta development</classLabel>
<deletedAxiom>&apos;embryonic placenta development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001890</classIRI>
<classLabel>placenta development</classLabel>
<deletedAxiom>&apos;placenta development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047119</classIRI>
<classLabel>2-methyl-branched-chain-enoyl-CoA reductase activity</classLabel>
<deletedAxiom>&apos;2-methyl-branched-chain-enoyl-CoA reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035174</classIRI>
<classLabel>histone serine kinase activity</classLabel>
<deletedAxiom>&apos;histone serine kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035175</classIRI>
<classLabel>histone kinase activity (H3-S10 specific)</classLabel>
<deletedAxiom>&apos;histone kinase activity (H3-S10 specific)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone H3-S10 phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035173</classIRI>
<classLabel>histone kinase activity</classLabel>
<deletedAxiom>&apos;histone kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047066</classIRI>
<classLabel>phospholipid-hydroperoxide glutathione peroxidase activity</classLabel>
<deletedAxiom>&apos;phospholipid-hydroperoxide glutathione peroxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on peroxide as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;phospholipid-hydroperoxide glutathione peroxidase activity&apos; SubClassOf &apos;peroxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035042</classIRI>
<classLabel>fertilization, exchange of chromosomal proteins</classLabel>
<deletedAxiom>&apos;fertilization, exchange of chromosomal proteins&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;fertilization, exchange of chromosomal proteins&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;sperm DNA decondensation&apos;</deletedAxiom>
<deletedAxiom>&apos;fertilization, exchange of chromosomal proteins&apos; SubClassOf &apos;histone exchange&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050568</classIRI>
<classLabel>protein-glutamine glutaminase activity</classLabel>
<newAxiom>&apos;protein-glutamine glutaminase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098518</classIRI>
<classLabel>polynucleotide phosphatase activity</classLabel>
<deletedAxiom>&apos;polynucleotide phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098519</classIRI>
<classLabel>nucleotide phosphatase activity, acting on free nucleotides</classLabel>
<deletedAxiom>&apos;nucleotide phosphatase activity, acting on free nucleotides&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001541</classIRI>
<classLabel>ovarian follicle development</classLabel>
<deletedAxiom>&apos;ovarian follicle development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;ovarian follicle development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</newAxiom>
<newAxiom>&apos;ovarian follicle development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050347</classIRI>
<classLabel>trans-octaprenyltranstransferase activity</classLabel>
<deletedAxiom>&apos;trans-octaprenyltranstransferase activity&apos; SubClassOf &apos;prenyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050333</classIRI>
<classLabel>thiamin-triphosphatase activity</classLabel>
<deletedAxiom>&apos;thiamin-triphosphatase activity&apos; SubClassOf &apos;nucleoside-triphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;thiamin-triphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050340</classIRI>
<classLabel>thymidylate 5&apos;-phosphatase activity</classLabel>
<deletedAxiom>&apos;thymidylate 5&apos;-phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;thymidylate 5&apos;-phosphatase activity&apos; SubClassOf &apos;5&apos;-nucleotidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015922</classIRI>
<classLabel>aspartate oxidase activity</classLabel>
<deletedAxiom>&apos;aspartate oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015976</classIRI>
<classLabel>carbon utilization</classLabel>
<deletedAxiom>&apos;carbon utilization&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<deletedAxiom>&apos;carbon utilization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;detection of organic substance&apos;</deletedAxiom>
<newAxiom>&apos;carbon utilization&apos; SubClassOf &apos;response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050232</classIRI>
<classLabel>putrescine oxidase activity</classLabel>
<deletedAxiom>&apos;putrescine oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;putrescine oxidase activity&apos; SubClassOf &apos;diamine oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050254</classIRI>
<classLabel>rhodopsin kinase activity</classLabel>
<deletedAxiom>&apos;rhodopsin kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;rhodopsin kinase activity&apos; SubClassOf &apos;G protein-coupled receptor kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003998</classIRI>
<classLabel>acylphosphatase activity</classLabel>
<deletedAxiom>&apos;acylphosphatase activity&apos; SubClassOf &apos;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides&apos;</deletedAxiom>
<newAxiom>&apos;acylphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003920</classIRI>
<classLabel>GMP reductase activity</classLabel>
<deletedAxiom>&apos;GMP reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;GMP reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001184</classIRI>
<classLabel>promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript</classLabel>
<deletedAxiom>&apos;promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nucleolar large rRNA transcription by RNA polymerase I&apos;</deletedAxiom>
<deletedAxiom>&apos;promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript&apos; SubClassOf &apos;promoter clearance from RNA polymerase I promoter&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001183</classIRI>
<classLabel>transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript</classLabel>
<deletedAxiom>&apos;transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nucleolar large rRNA transcription by RNA polymerase I&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript&apos; SubClassOf &apos;transcription elongation from RNA polymerase I promoter&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062103</classIRI>
<classLabel>double-stranded RNA biosynthetic process</classLabel>
<deletedAxiom>&apos;double-stranded RNA biosynthetic process&apos; SubClassOf &apos;RNA biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003853</classIRI>
<classLabel>2-methylacyl-CoA dehydrogenase activity</classLabel>
<newAxiom>&apos;2-methylacyl-CoA dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050173</classIRI>
<classLabel>phenylalanine adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;phenylalanine adenylyltransferase activity&apos; SubClassOf &apos;adenylyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062158</classIRI>
<classLabel>chloride:proton antiporter activity</classLabel>
<deletedAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;inorganic anion exchanger activity&apos;</newAxiom>
<newAxiom>&apos;chloride:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015747</classIRI>
<classLabel>urate transport</classLabel>
<newAxiom>&apos;urate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904488</classIRI>
<classLabel>regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of reactive oxygen species metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;reactive oxygen species metabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904489</classIRI>
<classLabel>regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;reactive oxygen species metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of reactive oxygen species metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904490</classIRI>
<classLabel>negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of response to stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitochondrial unfolded protein response&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitochondrial unfolded protein response&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of cellular response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062057</classIRI>
<classLabel>L-aspartate:fumarate antiporter activity</classLabel>
<deletedAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;L-aspartate:fumarate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003700</classIRI>
<classLabel>DNA-binding transcription factor activity</classLabel>
<newAxiom>&apos;DNA-binding transcription factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of transcription, DNA-templated&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052593</classIRI>
<classLabel>tryptamine:oxygen oxidoreductase (deaminating) activity</classLabel>
<deletedAxiom>&apos;tryptamine:oxygen oxidoreductase (deaminating) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;tryptamine:oxygen oxidoreductase (deaminating) activity&apos; SubClassOf &apos;aliphatic-amine oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052598</classIRI>
<classLabel>histamine oxidase activity</classLabel>
<deletedAxiom>&apos;histamine oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;histamine oxidase activity&apos; SubClassOf &apos;diamine oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015515</classIRI>
<classLabel>citrate:succinate antiporter activity</classLabel>
<deletedAxiom>&apos;citrate:succinate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;citrate:succinate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015516</classIRI>
<classLabel>tartrate:succinate antiporter activity</classLabel>
<deletedAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;tartrate:succinate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015520</classIRI>
<classLabel>tetracycline:proton antiporter activity</classLabel>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;tetracycline:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015496</classIRI>
<classLabel>putrescine:ornithine antiporter activity</classLabel>
<deletedAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;putrescine:ornithine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015491</classIRI>
<classLabel>cation:cation antiporter activity</classLabel>
<deletedAxiom>&apos;cation:cation antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cation:cation antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cation:cation antiporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015367</classIRI>
<classLabel>oxoglutarate:malate antiporter activity</classLabel>
<deletedAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;oxoglutarate:malate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015368</classIRI>
<classLabel>calcium:cation antiporter activity</classLabel>
<deletedAxiom>&apos;calcium:cation antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;calcium:cation antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140828</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015364</classIRI>
<classLabel>dicarboxylate:inorganic phosphate antiporter activity</classLabel>
<deletedAxiom>&apos;dicarboxylate:inorganic phosphate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;dicarboxylate:inorganic phosphate antiporter activity&apos; SubClassOf &apos;inorganic anion exchanger activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042962</classIRI>
<classLabel>acridine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acridine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015383</classIRI>
<classLabel>sulfate:bicarbonate antiporter activity</classLabel>
<deletedAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf &apos;bicarbonate transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140829</newAxiom>
<newAxiom>&apos;sulfate:bicarbonate antiporter activity&apos; SubClassOf &apos;inorganic anion exchanger activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990853</classIRI>
<classLabel>histone H2A SQE motif phosphorylation</classLabel>
<deletedAxiom>&apos;histone H2A SQE motif phosphorylation&apos; SubClassOf &apos;histone H2A phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A SQE motif phosphorylation&apos; SubClassOf &apos;peptidyl-serine phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015301</classIRI>
<classLabel>anion:anion antiporter activity</classLabel>
<deletedAxiom>&apos;anion:anion antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;anion:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;anion:anion antiporter activity&apos; SubClassOf &apos;anion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015309</classIRI>
<classLabel>cycloheximide:proton antiporter activity</classLabel>
<deletedAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cycloheximide:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015308</classIRI>
<classLabel>amiloride:proton antiporter activity</classLabel>
<deletedAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;amiloride:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015315</classIRI>
<classLabel>organophosphate:inorganic phosphate antiporter activity</classLabel>
<deletedAxiom>&apos;organophosphate:inorganic phosphate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;organophosphate:inorganic phosphate antiporter activity&apos; SubClassOf &apos;inorganic anion exchanger activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015312</classIRI>
<classLabel>polyamine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;polyamine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015310</classIRI>
<classLabel>benomyl:proton antiporter activity</classLabel>
<deletedAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;benomyl:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015311</classIRI>
<classLabel>monoamine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;monoamine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015327</classIRI>
<classLabel>cystine:glutamate antiporter activity</classLabel>
<deletedAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;cystine:glutamate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015325</classIRI>
<classLabel>acetyl-CoA:CoA antiporter activity</classLabel>
<deletedAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;acetyl-CoA:CoA antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015299</classIRI>
<classLabel>solute:proton antiporter activity</classLabel>
<deletedAxiom>&apos;solute:proton antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;solute:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;solute:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015298</classIRI>
<classLabel>solute:cation antiporter activity</classLabel>
<newAxiom>&apos;solute:cation antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;solute:cation antiporter activity&apos; SubClassOf &apos;cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005451</classIRI>
<classLabel>monovalent cation:proton antiporter activity</classLabel>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;monovalent cation:proton antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005452</classIRI>
<classLabel>inorganic anion exchanger activity</classLabel>
<deletedAxiom>&apos;inorganic anion exchanger activity&apos; SubClassOf &apos;secondary active transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;inorganic anion exchanger activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005469</classIRI>
<classLabel>succinate:fumarate antiporter activity</classLabel>
<deletedAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;succinate:fumarate antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005471</classIRI>
<classLabel>ATP:ADP antiporter activity</classLabel>
<deletedAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;ATP:ADP antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005476</classIRI>
<classLabel>carnitine:acyl carnitine antiporter activity</classLabel>
<deletedAxiom>&apos;carnitine:acyl carnitine antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;carnitine:acyl carnitine antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140818</classIRI>
<classLabel>mRNA 5&apos;-phosphatase activity</classLabel>
<deletedAxiom>&apos;mRNA 5&apos;-phosphatase activity&apos; SubClassOf &apos;polynucleotide 5&apos;-phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;mRNA 5&apos;-phosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140813</classIRI>
<classLabel>urate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;urate:anion antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140812</classIRI>
<classLabel>orotate:anion antiporter activity</classLabel>
<deletedAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;active ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;orotate:anion antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140800</classIRI>
<classLabel>gamma-aminobutyric acid:proton antiporter activity</classLabel>
<deletedAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;gamma-aminobutyric acid:proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140799</classIRI>
<classLabel>glycine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
<newAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;glycine:proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140708</classIRI>
<classLabel>CAT tailing</classLabel>
<newAxiom>&apos;CAT tailing&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;rescue of stalled ribosome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140665</classIRI>
<classLabel>ATP-dependent H3-H4 histone complex chaperone activity</classLabel>
<newAxiom>&apos;ATP-dependent H3-H4 histone complex chaperone activity&apos; SubClassOf &apos;H3-H4 histone complex chaperone activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005278</classIRI>
<classLabel>acetylcholine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900400</classIRI>
<classLabel>regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of cellular localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of iron ion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;iron import into cell&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;regulation of biological process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;transcription by RNA polymerase II&apos;) and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;iron import into cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900404</classIRI>
<classLabel>positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;regulation of biological process&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;positive regulation of DNA repair by transcription from RNA polymerase II promoter&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;positive regulation of DNA repair by transcription from RNA polymerase II promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of DNA repair&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019740</classIRI>
<classLabel>nitrogen utilization</classLabel>
<deletedAxiom>&apos;nitrogen utilization&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<newAxiom>&apos;nitrogen utilization&apos; SubClassOf &apos;response to nutrient levels&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019628</classIRI>
<classLabel>urate catabolic process</classLabel>
<deletedAxiom>&apos;urate catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;urate catabolic process&apos; SubClassOf &apos;purine-containing compound catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140407</classIRI>
<classLabel>L-alanine:proton antiporter activity</classLabel>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;monovalent cation:proton antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;anion:anion antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140848</newAxiom>
<newAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;solute:proton antiporter activity&apos;</newAxiom>
<newAxiom>&apos;L-alanine:proton antiporter activity&apos; SubClassOf &apos;solute:anion antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044667</classIRI>
<classLabel>(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity</classLabel>
<deletedAxiom>&apos;(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity&apos; SubClassOf &apos;cation:cation antiporter activity&apos;</deletedAxiom>
<newAxiom>&apos;(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity&apos; SubClassOf &apos;solute:cation antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900622</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling&apos; SubClassOf &apos;calcium-mediated signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling&apos; EquivalentTo &apos;calcium-mediated signaling&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;transcription by RNA polymerase II&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007506</classIRI>
<classLabel>gonadal mesoderm development</classLabel>
<deletedAxiom>&apos;gonadal mesoderm development&apos; SubClassOf &apos;reproductive structure development&apos;</deletedAxiom>
<newAxiom>&apos;gonadal mesoderm development&apos; SubClassOf &apos;developmental process involved in reproduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140110</classIRI>
<classLabel>transcription regulator activity</classLabel>
<deletedAxiom>&apos;transcription regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of transcription, DNA-templated&apos;</deletedAxiom>
<newAxiom>&apos;transcription regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;DNA-templated transcription, elongation&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120331</classIRI>
<classLabel>endothelial tube formation</classLabel>
<newAxiom>'endothelial tube formation' SubClassOf 'epithelial tube formation'</newAxiom>
<newAxiom>'endothelial tube formation' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'endothelial tube morphogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160031</classIRI>
<classLabel>endoplasmic reticulum membrane biogenesis</classLabel>
<newAxiom>'endoplasmic reticulum membrane biogenesis' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'endoplasmic reticulum membrane organization'</newAxiom>
<newAxiom>'endoplasmic reticulum membrane biogenesis' SubClassOf 'membrane biogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160030</classIRI>
<classLabel>pollen intine formation</classLabel>
<newAxiom>'pollen intine formation' SubClassOf 'pollen wall assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106424</classIRI>
<classLabel>succinyl-CoA 3-ketoacid-CoA transferase activity</classLabel>
<newAxiom>'succinyl-CoA 3-ketoacid-CoA transferase activity' SubClassOf '3-oxoacid CoA-transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106423</classIRI>
<classLabel>tubulin-tyrosine carboxypeptidase</classLabel>
<newAxiom>'tubulin-tyrosine carboxypeptidase' SubClassOf 'metallocarboxypeptidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140853</classIRI>
<classLabel>cholesterol-protein transferase activity</classLabel>
<newAxiom>'cholesterol-protein transferase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'cholesterol-protein transferase activity' SubClassOf 'transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140852</classIRI>
<classLabel>histone ubiquitin ligase activity</classLabel>
<newAxiom>'histone ubiquitin ligase activity' SubClassOf 'ubiquitin protein ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140851</classIRI>
<classLabel>histone ubiquitin ligase activity (H3-K14 specific)</classLabel>
<newAxiom>'histone ubiquitin ligase activity (H3-K14 specific)' SubClassOf 'histone ubiquitin ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140850</classIRI>
<classLabel>histone ubiquitin ligase activity (H2B-K120 specific)</classLabel>
<newAxiom>'histone ubiquitin ligase activity (H2B-K120 specific)' SubClassOf 'histone ubiquitin ligase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140849</classIRI>
<classLabel>ATP-dependent H2AZ histone chaperone activity</classLabel>
<newAxiom>'ATP-dependent H2AZ histone chaperone activity' SubClassOf 'ATP-dependent histone chaperone activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140848</classIRI>
<classLabel>amino acid:monoatomic cation antiporter activity</classLabel>
<newAxiom>'amino acid:monoatomic cation antiporter activity' SubClassOf 'amino acid transmembrane transporter activity'</newAxiom>
<newAxiom>'amino acid:monoatomic cation antiporter activity' SubClassOf 'solute:cation antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140847</classIRI>
<classLabel>negative regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<newAxiom>'negative regulation of promoter clearance from RNA polymerase II promoter' SubClassOf 'biological regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140842</classIRI>
<classLabel>RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity' SubClassOf 'RNA polymerase II C-terminal domain O-GlcNAc transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140841</classIRI>
<classLabel>RNA polymerase II C-terminal domain O-GlcNAc transferase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain O-GlcNAc transferase activity' SubClassOf 'protein O-GlcNAc transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140840</classIRI>
<classLabel>RNA polymerase II C-terminal domain P6 isomerase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain P6 isomerase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140846</classIRI>
<classLabel>positive regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<newAxiom>'positive regulation of promoter clearance from RNA polymerase II promoter' SubClassOf 'biological regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140845</classIRI>
<classLabel>regulation of promoter clearance from RNA polymerase II promoter</classLabel>
<newAxiom>'regulation of promoter clearance from RNA polymerase II promoter' SubClassOf 'biological regulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140844</classIRI>
<classLabel>NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E2 specific)</classLabel>
<newAxiom>'NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E2 specific)' SubClassOf 'NAD+-protein-glutamate ADP-ribosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140843</classIRI>
<classLabel>RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity' SubClassOf 'RNA polymerase II C-terminal domain O-GlcNAc transferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140839</classIRI>
<classLabel>RNA polymerase II C-terminal domain P3 isomerase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain P3 isomerase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140838</classIRI>
<classLabel>RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity</classLabel>
<newAxiom>'RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity' SubClassOf 'peptidyl-prolyl cis-trans isomerase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140837</classIRI>
<classLabel>RNA polymerase II C-terminal domain S7 kinase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain S7 kinase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140836</classIRI>
<classLabel>RNA polymerase II C-terminal domain S5 kinase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain S5 kinase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140831</classIRI>
<classLabel>L-asparagine, sodium:proton antiporter activity</classLabel>
<newAxiom>'L-asparagine, sodium:proton antiporter activity' SubClassOf 'solute:anion antiporter activity'</newAxiom>
<newAxiom>'L-asparagine, sodium:proton antiporter activity' SubClassOf 'L-asparagine transmembrane transporter activity'</newAxiom>
<newAxiom>'L-asparagine, sodium:proton antiporter activity' SubClassOf 'amino acid:monoatomic cation antiporter activity'</newAxiom>
<newAxiom>'L-asparagine, sodium:proton antiporter activity' SubClassOf 'sodium:proton antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140830</classIRI>
<classLabel>L-glutamine, sodium:proton antiporter activity</classLabel>
<newAxiom>'L-glutamine, sodium:proton antiporter activity' SubClassOf 'L-glutamine transmembrane transporter activity'</newAxiom>
<newAxiom>'L-glutamine, sodium:proton antiporter activity' SubClassOf 'sodium:proton antiporter activity'</newAxiom>
<newAxiom>'L-glutamine, sodium:proton antiporter activity' SubClassOf 'solute:anion antiporter activity'</newAxiom>
<newAxiom>'L-glutamine, sodium:proton antiporter activity' SubClassOf 'amino acid:monoatomic cation antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140835</classIRI>
<classLabel>RNA polymerase II C-terminal domain T4 kinase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain T4 kinase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140834</classIRI>
<classLabel>RNA polymerase II C-terminal domain S2 kinase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain S2 kinase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140833</classIRI>
<classLabel>RNA polymerase II C-terminal domain Y1 kinase activity</classLabel>
<newAxiom>'RNA polymerase II C-terminal domain Y1 kinase activity' SubClassOf 'RNA polymerase II CTD heptapeptide repeat kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140832</classIRI>
<classLabel>L-histidine, sodium:proton antiporter activity</classLabel>
<newAxiom>'L-histidine, sodium:proton antiporter activity' SubClassOf 'L-histidine transmembrane transporter activity'</newAxiom>
<newAxiom>'L-histidine, sodium:proton antiporter activity' SubClassOf 'azole:proton antiporter activity'</newAxiom>
<newAxiom>'L-histidine, sodium:proton antiporter activity' SubClassOf 'amino acid:monoatomic cation antiporter activity'</newAxiom>
<newAxiom>'L-histidine, sodium:proton antiporter activity' SubClassOf 'sodium:proton antiporter activity'</newAxiom>
<newAxiom>'L-histidine, sodium:proton antiporter activity' SubClassOf 'solute:anion antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140828</classIRI>
<classLabel>metal cation:monoatomic cation antiporter activity</classLabel>
<newAxiom>'metal cation:monoatomic cation antiporter activity' SubClassOf 'metal ion transmembrane transporter activity'</newAxiom>
<newAxiom>'metal cation:monoatomic cation antiporter activity' SubClassOf 'solute:cation antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140827</classIRI>
<classLabel>zinc chaperone activity</classLabel>
<newAxiom>'zinc chaperone activity' SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some 'zinc ion binding'</newAxiom>
<newAxiom>'zinc chaperone activity' SubClassOf 'metallochaperone activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140826</classIRI>
<classLabel>zinc:proton antiporter activity</classLabel>
<newAxiom>'zinc:proton antiporter activity' SubClassOf 'metal cation:proton antiporter activity'</newAxiom>
<newAxiom>'zinc:proton antiporter activity' SubClassOf 'transition metal ion transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140825</classIRI>
<classLabel>lactoperoxidase activity</classLabel>
<newAxiom>'lactoperoxidase activity' SubClassOf 'peroxidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140829</classIRI>
<classLabel>bicarbonate:anion antiporter activity</classLabel>
<newAxiom>'bicarbonate:anion antiporter activity' SubClassOf 'active ion transmembrane transporter activity'</newAxiom>
<newAxiom>'bicarbonate:anion antiporter activity' SubClassOf 'bicarbonate transmembrane transporter activity'</newAxiom>
<newAxiom>'bicarbonate:anion antiporter activity' SubClassOf 'solute:anion antiporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140824</classIRI>
<classLabel>thioredoxin-dependent peroxiredoxin activity</classLabel>
<newAxiom>'thioredoxin-dependent peroxiredoxin activity' SubClassOf 'peroxiredoxin activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140823</classIRI>
<classLabel>histone kinase activity (H2B-S36 specific)</classLabel>
<newAxiom>'histone kinase activity (H2B-S36 specific)' SubClassOf 'histone serine kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140822</classIRI>
<classLabel>NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E35 specific)</classLabel>
<newAxiom>'NAD+-histone-glutamate ADP-ribosyltransferase activity (H2B-E35 specific)' SubClassOf 'NAD+-protein-glutamate ADP-ribosyltransferase activity'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103073</classIRI>
<classLabel>anandamide amidohydrolase activity</classLabel>
<newAxiom>'anandamide amidohydrolase activity' SubClassOf 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036422</classIRI>
<classLabel>heptaprenyl diphosphate synthase activity</classLabel>
<newAxiom>'heptaprenyl diphosphate synthase activity' SubClassOf 'prenyltransferase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102668</classIRI>
<classLabel>liquiritigenin,NADPH:oxygen oxidoreductase activity</classLabel>
<newAxiom>'liquiritigenin,NADPH:oxygen oxidoreductase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102604</classIRI>
<classLabel>naringenin,NADPH:oxygen oxidoreductase activity</classLabel>
<newAxiom>'naringenin,NADPH:oxygen oxidoreductase activity' SubClassOf 'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043458</classIRI>
<classLabel>ethanol biosynthetic process involved in glucose fermentation to ethanol</classLabel>
<newAxiom>'ethanol biosynthetic process involved in glucose fermentation to ethanol' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'glycolytic fermentation to ethanol'</newAxiom>
<newAxiom>'ethanol biosynthetic process involved in glucose fermentation to ethanol' SubClassOf 'ethanol biosynthetic process'</newAxiom>
<newAxiom>'ethanol biosynthetic process involved in glucose fermentation to ethanol' EquivalentTo 'ethanol biosynthetic process' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'glycolytic fermentation to ethanol')</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102077</classIRI>
<classLabel>oleamide hydrolase activity</classLabel>
<newAxiom>'oleamide hydrolase activity' SubClassOf 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047119</classIRI>
<classLabel>2-methyl-branched-chain-enoyl-CoA reductase activity</classLabel>
<newAxiom>'2-methyl-branched-chain-enoyl-CoA reductase activity' SubClassOf 'oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050347</classIRI>
<classLabel>trans-octaprenyltranstransferase activity</classLabel>
<newAxiom>'trans-octaprenyltranstransferase activity' SubClassOf 'prenyltransferase activity'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001184</classIRI>
<classLabel>promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript</classLabel>
<newAxiom>'promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'nucleolar large rRNA transcription by RNA polymerase I'</newAxiom>
<newAxiom>'promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript' SubClassOf 'promoter clearance from RNA polymerase I promoter'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001183</classIRI>
<classLabel>transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript</classLabel>
<newAxiom>'transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'nucleolar large rRNA transcription by RNA polymerase I'</newAxiom>
<newAxiom>'transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript' SubClassOf 'transcription elongation from RNA polymerase I promoter'</newAxiom>
</deletedClass>
<deletedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062103</classIRI>
<classLabel>double-stranded RNA biosynthetic process</classLabel>
<newAxiom>'double-stranded RNA biosynthetic process' SubClassOf 'RNA biosynthetic process'</newAxiom>
</deletedClass>
</deletedClasses>
</diffReport>