<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
323
</numberChangedClasses>
<numberNewClasses>
37
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071893</classIRI>
<classLabel>BMP signaling pathway involved in nephric duct formation</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in nephric duct formation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nephric duct formation&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in nephric duct formation&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in nephric duct formation&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nephric duct formation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009860</classIRI>
<classLabel>pollen tube growth</classLabel>
<deletedAxiom>&apos;pollen tube growth&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007200</classIRI>
<classLabel>phospholipase C-activating G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;phospholipase C-activating G protein-coupled receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;inositol phosphate-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010862</classIRI>
<classLabel>positive regulation of pathway-restricted SMAD protein phosphorylation</classLabel>
<deletedAxiom>&apos;positive regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;pathway-restricted SMAD protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of pathway-restricted SMAD protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;pathway-restricted SMAD protein phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;regulation of pathway-restricted SMAD protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;positive regulation of protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007249</classIRI>
<classLabel>I-kappaB kinase/NF-kappaB signaling</classLabel>
<deletedAxiom>&apos;I-kappaB kinase/NF-kappaB signaling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007182</classIRI>
<classLabel>common-partner SMAD protein phosphorylation</classLabel>
<deletedAxiom>&apos;common-partner SMAD protein phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;common-partner SMAD protein phosphorylation&apos; SubClassOf &apos;protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032187</classIRI>
<classLabel>actomyosin contractile ring localization</classLabel>
<deletedAxiom>&apos;actomyosin contractile ring localization&apos; SubClassOf &apos;contractile ring localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032189</classIRI>
<classLabel>maintenance of actomyosin contractile ring localization</classLabel>
<deletedAxiom>&apos;maintenance of actomyosin contractile ring localization&apos; SubClassOf &apos;actomyosin contractile ring localization&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of actomyosin contractile ring localization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;actomyosin contractile ring maintenance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010769</classIRI>
<classLabel>regulation of cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;regulation of cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell morphogenesis involved in differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cell morphogenesis involved in differentiation&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010771</classIRI>
<classLabel>negative regulation of cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell morphogenesis involved in differentiation&apos;)</deletedAxiom>
<newAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
<newAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell morphogenesis&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010770</classIRI>
<classLabel>positive regulation of cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cell morphogenesis involved in differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cell morphogenesis&apos;</newAxiom>
<newAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cell morphogenesis&apos;)</newAxiom>
<newAxiom>&apos;positive regulation of cell morphogenesis involved in differentiation&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044066</classIRI>
<classLabel>modification by symbiont of host cell nucleus</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell nucleus&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host cell nucleus&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044067</classIRI>
<classLabel>modification by symbiont of host cell-cell junction</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell-cell junction&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host cell-cell junction&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071678</classIRI>
<classLabel>olfactory bulb axon guidance</classLabel>
<newAxiom>&apos;olfactory bulb axon guidance&apos; SubClassOf &apos;cell proliferation in forebrain&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044071</classIRI>
<classLabel>modulation by symbiont of host cell cycle</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host cell cycle&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host cell cycle&apos; SubClassOf &apos;regulation of cell cycle process&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host cell cycle&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;)</newAxiom>
<newAxiom>&apos;modulation by symbiont of host cell cycle&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010629</classIRI>
<classLabel>negative regulation of gene expression</classLabel>
<deletedAxiom>&apos;negative regulation of gene expression&apos; SubClassOf &apos;negative regulation of macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gene expression&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010628</classIRI>
<classLabel>positive regulation of gene expression</classLabel>
<deletedAxiom>&apos;positive regulation of gene expression&apos; SubClassOf &apos;positive regulation of macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of gene expression&apos; SubClassOf &apos;positive regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009678</classIRI>
<classLabel>pyrophosphate hydrolysis-driven proton transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyrophosphate hydrolysis-driven proton transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyrophosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;pyrophosphate hydrolysis-driven proton transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;inorganic diphosphate phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034519</classIRI>
<classLabel>cytoplasmic RNA cap binding complex</classLabel>
<deletedAxiom>&apos;cytoplasmic RNA cap binding complex&apos; SubClassOf &apos;RNA cap binding complex&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic RNA cap binding complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytosol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034518</classIRI>
<classLabel>RNA cap binding complex</classLabel>
<deletedAxiom>&apos;RNA cap binding complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;RNA cap binding complex&apos; SubClassOf &apos;intracellular protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010556</classIRI>
<classLabel>regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010557</classIRI>
<classLabel>positive regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010558</classIRI>
<classLabel>negative regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034412</classIRI>
<classLabel>ascospore wall beta-glucan biosynthetic process</classLabel>
<newAxiom>&apos;ascospore wall beta-glucan biosynthetic process&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010467</classIRI>
<classLabel>gene expression</classLabel>
<deletedAxiom>&apos;gene expression&apos; SubClassOf &apos;macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;gene expression&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010468</classIRI>
<classLabel>regulation of gene expression</classLabel>
<deletedAxiom>&apos;regulation of gene expression&apos; SubClassOf &apos;regulation of macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gene expression&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010431</classIRI>
<classLabel>seed maturation</classLabel>
<deletedAxiom>&apos;seed maturation&apos; SubClassOf &apos;anatomical structure maturation&apos;</deletedAxiom>
<newAxiom>&apos;seed maturation&apos; SubClassOf &apos;developmental maturation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010442</classIRI>
<classLabel>guard cell morphogenesis</classLabel>
<deletedAxiom>&apos;guard cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;guard cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048940</classIRI>
<classLabel>anterior lateral line nerve glial cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;anterior lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis involved in differentiation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;anterior lateral line nerve glial cell development&apos;)</deletedAxiom>
<newAxiom>&apos;anterior lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;anterior lateral line nerve glial cell development&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048942</classIRI>
<classLabel>posterior lateral line nerve glial cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;posterior lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis involved in differentiation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;posterior lateral line nerve glial cell development&apos;)</deletedAxiom>
<newAxiom>&apos;posterior lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;posterior lateral line nerve glial cell development&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048938</classIRI>
<classLabel>lateral line nerve glial cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis involved in differentiation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lateral line nerve glial cell development&apos;)</deletedAxiom>
<deletedAxiom>&apos;lateral line nerve glial cell morphogenesis involved in differentiation&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;lateral line nerve glial cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;lateral line nerve glial cell development&apos;)</newAxiom>
<newAxiom>&apos;lateral line nerve glial cell morphogenesis involved in differentiation&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061924</classIRI>
<classLabel>regulation of formation of radial glial scaffolds</classLabel>
<deletedAxiom>&apos;regulation of formation of radial glial scaffolds&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of formation of radial glial scaffolds&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000904</classIRI>
<classLabel>cell morphogenesis involved in differentiation</classLabel>
<deletedAxiom>&apos;cell morphogenesis involved in differentiation&apos; SubClassOf &apos;cell morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;cell morphogenesis involved in differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell development&apos;</deletedAxiom>
<deletedAxiom>&apos;cell morphogenesis involved in differentiation&apos; EquivalentTo &apos;cell morphogenesis&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell development&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034217</classIRI>
<classLabel>ascospore wall chitin biosynthetic process</classLabel>
<deletedAxiom>&apos;ascospore wall chitin biosynthetic process&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<newAxiom>&apos;ascospore wall chitin biosynthetic process&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034223</classIRI>
<classLabel>regulation of ascospore wall chitin biosynthetic process</classLabel>
<newAxiom>&apos;regulation of ascospore wall chitin biosynthetic process&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034246</classIRI>
<classLabel>mitochondrial transcription factor activity</classLabel>
<deletedAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;transcription regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;DNA-binding transcription factor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000712</classIRI>
<classLabel>resolution of meiotic recombination intermediates</classLabel>
<deletedAxiom>&apos;resolution of meiotic recombination intermediates&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic chromosome segregation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048768</classIRI>
<classLabel>root hair cell tip growth</classLabel>
<deletedAxiom>&apos;root hair cell tip growth&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048766</classIRI>
<classLabel>root hair initiation</classLabel>
<deletedAxiom>&apos;root hair initiation&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;root hair initiation&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061765</classIRI>
<classLabel>modulation by virus of host NIK/NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;modulation by virus of host NIK/NF-kappaB cascade&apos; SubClassOf &apos;modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host NIK/NF-kappaB cascade&apos; SubClassOf &apos;modulation by symbiont of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061792</classIRI>
<classLabel>secretory granule maturation</classLabel>
<deletedAxiom>&apos;secretory granule maturation&apos; SubClassOf &apos;developmental maturation&apos;</deletedAxiom>
<newAxiom>&apos;secretory granule maturation&apos; SubClassOf &apos;anatomical structure maturation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048601</classIRI>
<classLabel>oocyte morphogenesis</classLabel>
<deletedAxiom>&apos;oocyte morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;oocyte morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022024</classIRI>
<classLabel>BMP signaling pathway involved in forebrain neuron fate commitment</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in forebrain neuron fate commitment&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;forebrain neuron fate commitment&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;commitment of multipotent stem cells to neuronal lineage in forebrain&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009059</classIRI>
<classLabel>macromolecule biosynthetic process</classLabel>
<newAxiom>&apos;macromolecule biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048667</classIRI>
<classLabel>cell morphogenesis involved in neuron differentiation</classLabel>
<deletedAxiom>&apos;cell morphogenesis involved in neuron differentiation&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;cell morphogenesis involved in neuron differentiation&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061614</classIRI>
<classLabel>miRNA transcription</classLabel>
<deletedAxiom>&apos;miRNA transcription&apos; SubClassOf &apos;DNA-templated transcription&apos;</deletedAxiom>
<newAxiom>&apos;miRNA transcription&apos; SubClassOf &apos;ncRNA transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010090</classIRI>
<classLabel>trichome morphogenesis</classLabel>
<deletedAxiom>&apos;trichome morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;trichome morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010091</classIRI>
<classLabel>trichome branching</classLabel>
<deletedAxiom>&apos;trichome branching&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;trichome branching&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000278</classIRI>
<classLabel>regulation of DNA biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of DNA biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000279</classIRI>
<classLabel>negative regulation of DNA biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of DNA biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000223</classIRI>
<classLabel>regulation of BMP signaling pathway involved in heart jogging</classLabel>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in heart jogging&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;BMP signaling pathway involved in heart jogging&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in heart jogging&apos; SubClassOf &apos;regulation of BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in heart jogging&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;BMP signaling pathway involved in heart jogging&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036521</classIRI>
<classLabel>modulation by symbiont of host protein localization to phagocytic vesicle</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host protein localization to phagocytic vesicle&apos; SubClassOf &apos;regulation of protein localization to phagocytic vesicle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061541</classIRI>
<classLabel>rhabdomere morphogenesis</classLabel>
<newAxiom>&apos;rhabdomere morphogenesis&apos; SubClassOf &apos;cell proliferation involved in compound eye morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097485</classIRI>
<classLabel>neuron projection guidance</classLabel>
<deletedAxiom>&apos;neuron projection guidance&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chemotaxis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036480</classIRI>
<classLabel>neuron intrinsic apoptotic signaling pathway in response to oxidative stress</classLabel>
<deletedAxiom>&apos;neuron intrinsic apoptotic signaling pathway in response to oxidative stress&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neuron death in response to oxidative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036475</classIRI>
<classLabel>neuron death in response to oxidative stress</classLabel>
<deletedAxiom>&apos;neuron death in response to oxidative stress&apos; SubClassOf &apos;neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061353</classIRI>
<classLabel>BMP signaling pathway involved in Malpighian tubule cell chemotaxis</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in Malpighian tubule cell chemotaxis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell chemotaxis involved in Malpighian tubule morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in Malpighian tubule cell chemotaxis&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell chemotaxis involved in Malpighian tubule morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in Malpighian tubule cell chemotaxis&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061372</classIRI>
<classLabel>activin receptor signaling pathway involved in heart jogging</classLabel>
<deletedAxiom>&apos;activin receptor signaling pathway involved in heart jogging&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;activin receptor signaling pathway involved in heart jogging&apos; EquivalentTo &apos;activin receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;)</deletedAxiom>
<deletedAxiom>&apos;activin receptor signaling pathway involved in heart jogging&apos; SubClassOf &apos;activin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;activin receptor signaling pathway involved in heart jogging&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061336</classIRI>
<classLabel>cell morphogenesis involved in Malpighian tubule morphogenesis</classLabel>
<deletedAxiom>&apos;cell morphogenesis involved in Malpighian tubule morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;cell morphogenesis involved in Malpighian tubule morphogenesis&apos; EquivalentTo &apos;cell morphogenesis involved in differentiation&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Malpighian tubule morphogenesis&apos;)</deletedAxiom>
<newAxiom>&apos;cell morphogenesis involved in Malpighian tubule morphogenesis&apos; EquivalentTo &apos;cell morphogenesis&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Malpighian tubule morphogenesis&apos;)</newAxiom>
<newAxiom>&apos;cell morphogenesis involved in Malpighian tubule morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000444</classIRI>
<classLabel>MIS12/MIND type complex</classLabel>
<deletedAxiom>&apos;MIS12/MIND type complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;inner kinetochore&apos;</deletedAxiom>
<deletedAxiom>&apos;MIS12/MIND type complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;MIS12/MIND type complex&apos; SubClassOf &apos;outer kinetochore&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097393</classIRI>
<classLabel>telomeric repeat-containing RNA transcription</classLabel>
<deletedAxiom>&apos;telomeric repeat-containing RNA transcription&apos; SubClassOf &apos;ncRNA metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097394</classIRI>
<classLabel>telomeric repeat-containing RNA transcription by RNA polymerase II</classLabel>
<deletedAxiom>&apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos; SubClassOf &apos;telomeric repeat-containing RNA transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos; SubClassOf &apos;transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036344</classIRI>
<classLabel>platelet morphogenesis</classLabel>
<deletedAxiom>&apos;platelet morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;platelet morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160076</classIRI>
<classLabel>negative regulation of non-canonical inflammasome complex assembly</classLabel>
<newAxiom>&apos;negative regulation of non-canonical inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141086</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061312</classIRI>
<classLabel>BMP signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in heart development&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart development&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart development&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart development&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014815</classIRI>
<classLabel>initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration</classLabel>
<deletedAxiom>&apos;initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration&apos; SubClassOf &apos;positive regulation of satellite cell activation involved in skeletal muscle regeneration&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002807</classIRI>
<classLabel>positive regulation of antimicrobial peptide biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of antimicrobial peptide biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002806</classIRI>
<classLabel>negative regulation of antimicrobial peptide biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of antimicrobial peptide biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002805</classIRI>
<classLabel>regulation of antimicrobial peptide biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of antimicrobial peptide biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036212</classIRI>
<classLabel>contractile ring maintenance</classLabel>
<deletedAxiom>&apos;contractile ring maintenance&apos; SubClassOf &apos;cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring maintenance&apos; SubClassOf &apos;cellular component maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring maintenance&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytoskeleton-dependent cytokinesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036210</classIRI>
<classLabel>protein modification process in another organism</classLabel>
<deletedAxiom>&apos;protein modification process in another organism&apos; SubClassOf &apos;modulation by symbiont of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;protein modification process in another organism&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061151</classIRI>
<classLabel>BMP signaling pathway involved in renal system segmentation</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in renal system segmentation&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in renal system segmentation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;renal system segmentation&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in renal system segmentation&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;renal system segmentation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061149</classIRI>
<classLabel>BMP signaling pathway involved in ureter morphogenesis</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in ureter morphogenesis&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in ureter morphogenesis&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ureter morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in ureter morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ureter morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048015</classIRI>
<classLabel>phosphatidylinositol-mediated signaling</classLabel>
<deletedAxiom>&apos;phosphatidylinositol-mediated signaling&apos; SubClassOf &apos;inositol lipid-mediated signaling&apos;</deletedAxiom>
<newAxiom>&apos;phosphatidylinositol-mediated signaling&apos; SubClassOf &apos;intracellular signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048016</classIRI>
<classLabel>inositol phosphate-mediated signaling</classLabel>
<deletedAxiom>&apos;inositol phosphate-mediated signaling&apos; SubClassOf &apos;second-messenger-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048017</classIRI>
<classLabel>inositol lipid-mediated signaling</classLabel>
<deletedAxiom>&apos;inositol lipid-mediated signaling&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051699</classIRI>
<classLabel>proline oxidase activity</classLabel>
<deletedAxiom>&apos;proline oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000573</classIRI>
<classLabel>positive regulation of DNA biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of DNA biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061088</classIRI>
<classLabel>regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;regulation of sequestering of zinc ion&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;sequestering of zinc ion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of sequestering of zinc ion&apos; SubClassOf &apos;regulation of localization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of sequestering of zinc ion&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of sequestering of zinc ion&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;sequestering of zinc ion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061090</classIRI>
<classLabel>positive regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;positive regulation of sequestering of zinc ion&apos; SubClassOf &apos;regulation of sequestering of zinc ion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sequestering of zinc ion&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sequestering of zinc ion&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;sequestering of zinc ion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of sequestering of zinc ion&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;sequestering of zinc ion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085044</classIRI>
<classLabel>disassembly by symbiont of host cuticle</classLabel>
<deletedAxiom>&apos;disassembly by symbiont of host cuticle&apos; SubClassOf &apos;disruption of anatomical structure in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061089</classIRI>
<classLabel>negative regulation of sequestering of zinc ion</classLabel>
<deletedAxiom>&apos;negative regulation of sequestering of zinc ion&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;sequestering of zinc ion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sequestering of zinc ion&apos; SubClassOf &apos;regulation of sequestering of zinc ion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sequestering of zinc ion&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sequestering of zinc ion&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;sequestering of zinc ion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085033</classIRI>
<classLabel>induction by symbiont of host I-kappaB kinase/NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;induction by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;positive regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085032</classIRI>
<classLabel>modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085034</classIRI>
<classLabel>disruption of host I-kappaB kinase/NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;disruption of host I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;negative regulation of I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
<newAxiom>&apos;disruption of host I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000539</classIRI>
<classLabel>regulation of protein geranylgeranylation</classLabel>
<deletedAxiom>&apos;regulation of protein geranylgeranylation&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002749</classIRI>
<classLabel>antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen</classLabel>
<deletedAxiom>&apos;antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen&apos; SubClassOf &apos;antigen processing and presentation following phagocytosis&apos;</deletedAxiom>
<deletedAxiom>&apos;antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen&apos; SubClassOf &apos;antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099565</classIRI>
<classLabel>chemical synaptic transmission, postsynaptic</classLabel>
<deletedAxiom>&apos;chemical synaptic transmission, postsynaptic&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
<newAxiom>&apos;chemical synaptic transmission, postsynaptic&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000803</classIRI>
<classLabel>endosomal signal transduction</classLabel>
<deletedAxiom>&apos;endosomal signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;endosomal signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;endosome&apos;</deletedAxiom>
<deletedAxiom>&apos;endosomal signal transduction&apos; EquivalentTo &apos;signal transduction&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;endosome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051512</classIRI>
<classLabel>positive regulation of unidimensional cell growth</classLabel>
<newAxiom>&apos;positive regulation of unidimensional cell growth&apos; SubClassOf &apos;positive regulation of cell morphogenesis involved in differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051511</classIRI>
<classLabel>negative regulation of unidimensional cell growth</classLabel>
<newAxiom>&apos;negative regulation of unidimensional cell growth&apos; SubClassOf &apos;negative regulation of cell morphogenesis involved in differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051482</classIRI>
<classLabel>positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway&apos; SubClassOf &apos;positive regulation of cytosolic calcium ion concentration&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway&apos; EquivalentTo &apos;positive regulation of cytosolic calcium ion concentration&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;phospholipase C-activating G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;phospholipase C-activating G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051456</classIRI>
<classLabel>attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation</classLabel>
<deletedAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic sister chromatid segregation&apos;</deletedAxiom>
<deletedAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic sister chromatid segregation&apos;)</deletedAxiom>
<newAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase II plate congression&apos;)</newAxiom>
<newAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase II plate congression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051455</classIRI>
<classLabel>monopolar spindle attachment to meiosis I kinetochore</classLabel>
<deletedAxiom>&apos;monopolar spindle attachment to meiosis I kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;homologous chromosome segregation&apos;</deletedAxiom>
<deletedAxiom>&apos;monopolar spindle attachment to meiosis I kinetochore&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;homologous chromosome segregation&apos;)</deletedAxiom>
<newAxiom>&apos;monopolar spindle attachment to meiosis I kinetochore&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase I plate congression&apos;)</newAxiom>
<newAxiom>&apos;monopolar spindle attachment to meiosis I kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase I plate congression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051402</classIRI>
<classLabel>neuron apoptotic process</classLabel>
<deletedAxiom>&apos;neuron apoptotic process&apos; SubClassOf &apos;neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051316</classIRI>
<classLabel>attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation</classLabel>
<deletedAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic chromosome segregation&apos;)</deletedAxiom>
<deletedAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic chromosome segregation&apos;</deletedAxiom>
<newAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation&apos; EquivalentTo &apos;attachment of spindle microtubules to kinetochore&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase plate congression&apos;)</newAxiom>
<newAxiom>&apos;attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic metaphase plate congression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903107</classIRI>
<classLabel>insulin receptor signaling pathway involved in dauer larval development</classLabel>
<deletedAxiom>&apos;insulin receptor signaling pathway involved in dauer larval development&apos; SubClassOf &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway involved in dauer larval development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;dauer larval development&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway involved in dauer larval development&apos; EquivalentTo &apos;insulin receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;dauer larval development&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110135</classIRI>
<classLabel>Norrin signaling pathway</classLabel>
<deletedAxiom>&apos;Norrin signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
<newAxiom>&apos;Norrin signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110073</classIRI>
<classLabel>regulation of apical constriction involved in ventral furrow formation</classLabel>
<deletedAxiom>&apos;regulation of apical constriction involved in ventral furrow formation&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of apical constriction involved in ventral furrow formation&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038103</classIRI>
<classLabel>activin receptor antagonist activity involved in negative regulation of nodal signaling pathway</classLabel>
<deletedAxiom>&apos;activin receptor antagonist activity involved in negative regulation of nodal signaling pathway&apos; EquivalentTo &apos;activin receptor antagonist activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;negative regulation of nodal signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;activin receptor antagonist activity involved in negative regulation of nodal signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;negative regulation of nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;activin receptor antagonist activity involved in negative regulation of nodal signaling pathway&apos; SubClassOf &apos;activin receptor antagonist activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903321</classIRI>
<classLabel>negative regulation of protein modification by small protein conjugation or removal</classLabel>
<deletedAxiom>&apos;negative regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;negative regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903320</classIRI>
<classLabel>regulation of protein modification by small protein conjugation or removal</classLabel>
<deletedAxiom>&apos;regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903322</classIRI>
<classLabel>positive regulation of protein modification by small protein conjugation or removal</classLabel>
<deletedAxiom>&apos;positive regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;positive regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein modification by small protein conjugation or removal&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038168</classIRI>
<classLabel>epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf &apos;epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;I-kappaB kinase/NF-kappaB signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038167</classIRI>
<classLabel>epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity</classLabel>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity&apos; SubClassOf &apos;epidermal growth factor receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075130</classIRI>
<classLabel>modulation by symbiont of host protein kinase-mediated signal transduction</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host protein kinase-mediated signal transduction&apos; SubClassOf &apos;modulation by symbiont of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075132</classIRI>
<classLabel>disruption of host protein kinase-mediated signal transduction</classLabel>
<deletedAxiom>&apos;disruption of host protein kinase-mediated signal transduction&apos; SubClassOf &apos;disruption of host signal transduction pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption of host protein kinase-mediated signal transduction&apos; SubClassOf &apos;modulation by symbiont of host protein kinase-mediated signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075118</classIRI>
<classLabel>modulation by symbiont of host G protein-coupled receptor signal transduction</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;regulation of G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075120</classIRI>
<classLabel>disruption of host G protein-coupled receptor signal transduction</classLabel>
<deletedAxiom>&apos;disruption of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;negative regulation of G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;disruption of host transmembrane receptor-mediated signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;disruption of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;disruption of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099116</classIRI>
<classLabel>tRNA 5&apos;-end processing</classLabel>
<deletedAxiom>&apos;tRNA 5&apos;-end processing&apos; SubClassOf &apos;RNA 5&apos;-end processing&apos;</deletedAxiom>
<newAxiom>&apos;tRNA 5&apos;-end processing&apos; SubClassOf &apos;ncRNA 5&apos;-end processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903376</classIRI>
<classLabel>regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;neuron death in response to oxidative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903377</classIRI>
<classLabel>negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;neuron death in response to oxidative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038029</classIRI>
<classLabel>epidermal growth factor receptor signaling pathway via MAPK cascade</classLabel>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway via MAPK cascade&apos; SubClassOf &apos;epidermal growth factor receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038028</classIRI>
<classLabel>insulin receptor signaling pathway via phosphatidylinositol 3-kinase</classLabel>
<deletedAxiom>&apos;insulin receptor signaling pathway via phosphatidylinositol 3-kinase&apos; SubClassOf &apos;insulin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;insulin receptor signaling pathway via phosphatidylinositol 3-kinase&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014067</classIRI>
<classLabel>negative regulation of phosphatidylinositol 3-kinase signaling</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;negative regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;phosphatidylinositol 3-kinase signaling&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014068</classIRI>
<classLabel>positive regulation of phosphatidylinositol 3-kinase signaling</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;positive regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphatidylinositol 3-kinase signaling&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014065</classIRI>
<classLabel>phosphatidylinositol 3-kinase signaling</classLabel>
<deletedAxiom>&apos;phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;phosphatidylinositol-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014066</classIRI>
<classLabel>regulation of phosphatidylinositol 3-kinase signaling</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphatidylinositol 3-kinase signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphatidylinositol 3-kinase signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038030</classIRI>
<classLabel>non-canonical Wnt signaling pathway via MAPK cascade</classLabel>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway via MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway via MAPK cascade&apos; SubClassOf &apos;non-canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038031</classIRI>
<classLabel>non-canonical Wnt signaling pathway via JNK cascade</classLabel>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;non-canonical Wnt signaling pathway via MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;non-canonical Wnt signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038061</classIRI>
<classLabel>NIK/NF-kappaB signaling</classLabel>
<deletedAxiom>&apos;NIK/NF-kappaB signaling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of NF-kappaB transcription factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002021</classIRI>
<classLabel>response to dietary excess</classLabel>
<deletedAxiom>&apos;response to dietary excess&apos; SubClassOf &apos;multicellular organismal process&apos;</deletedAxiom>
<newAxiom>&apos;response to dietary excess&apos; SubClassOf &apos;energy homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016570</classIRI>
<classLabel>histone modification</classLabel>
<deletedAxiom>&apos;histone modification&apos; SubClassOf &apos;protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;histone modification&apos; SubClassOf &apos;post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901048</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of multicellular organism growth&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of multicellular organism growth&apos;)</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090378</classIRI>
<classLabel>seed trichome elongation</classLabel>
<deletedAxiom>&apos;seed trichome elongation&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901214</classIRI>
<classLabel>regulation of neuron death</classLabel>
<deletedAxiom>&apos;regulation of neuron death&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;neuron death&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of neuron death&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of neuron death&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901215</classIRI>
<classLabel>negative regulation of neuron death</classLabel>
<deletedAxiom>&apos;negative regulation of neuron death&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of neuron death&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;neuron death&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of neuron death&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;neuron death&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of neuron death&apos; SubClassOf &apos;regulation of neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901216</classIRI>
<classLabel>positive regulation of neuron death</classLabel>
<deletedAxiom>&apos;positive regulation of neuron death&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of neuron death&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;neuron death&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of neuron death&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;neuron death&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of neuron death&apos; SubClassOf &apos;regulation of neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000039</classIRI>
<classLabel>regulation of trichome morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of trichome morphogenesis&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of trichome morphogenesis&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016281</classIRI>
<classLabel>eukaryotic translation initiation factor 4F complex</classLabel>
<deletedAxiom>&apos;eukaryotic translation initiation factor 4F complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;eukaryotic translation initiation factor 4F complex&apos; SubClassOf &apos;RNA cap binding complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102662</classIRI>
<classLabel>malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity</classLabel>
<deletedAxiom>&apos;malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090153</classIRI>
<classLabel>regulation of sphingolipid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of sphingolipid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090171</classIRI>
<classLabel>chondrocyte morphogenesis</classLabel>
<deletedAxiom>&apos;chondrocyte morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;chondrocyte morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090013</classIRI>
<classLabel>regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation</classLabel>
<deletedAxiom>&apos;regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf &apos;regulation of transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090012</classIRI>
<classLabel>negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation</classLabel>
<deletedAxiom>&apos;negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf &apos;regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf &apos;negative regulation of transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090010</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in primitive streak formation</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;primitive streak formation&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in primitive streak formation&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;primitive streak formation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901580</classIRI>
<classLabel>regulation of telomeric RNA transcription from RNA pol II promoter</classLabel>
<deletedAxiom>&apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;regulation of ncRNA transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901581</classIRI>
<classLabel>negative regulation of telomeric RNA transcription from RNA pol II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of telomeric RNA transcription from RNA pol II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901582</classIRI>
<classLabel>positive regulation of telomeric RNA transcription from RNA pol II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of telomeric RNA transcription from RNA pol II promoter&apos; SubClassOf &apos;regulation of telomeric RNA transcription from RNA pol II promoter&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of telomeric RNA transcription from RNA pol II promoter&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;telomeric repeat-containing RNA transcription by RNA polymerase II&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031619</classIRI>
<classLabel>homologous chromosome orientation involved in meiotic metaphase I plate congression</classLabel>
<deletedAxiom>&apos;homologous chromosome orientation involved in meiotic metaphase I plate congression&apos; SubClassOf &apos;monopolar spindle attachment to meiosis I kinetochore&apos;</deletedAxiom>
<newAxiom>&apos;homologous chromosome orientation involved in meiotic metaphase I plate congression&apos; SubClassOf &apos;reproductive process&apos;</newAxiom>
<newAxiom>&apos;homologous chromosome orientation involved in meiotic metaphase I plate congression&apos; SubClassOf &apos;chromosome localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016055</classIRI>
<classLabel>Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;Wnt signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
<newAxiom>&apos;Wnt signaling pathway&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016063</classIRI>
<classLabel>rhodopsin biosynthetic process</classLabel>
<deletedAxiom>&apos;rhodopsin biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043523</classIRI>
<classLabel>regulation of neuron apoptotic process</classLabel>
<deletedAxiom>&apos;regulation of neuron apoptotic process&apos; SubClassOf &apos;regulation of neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043524</classIRI>
<classLabel>negative regulation of neuron apoptotic process</classLabel>
<deletedAxiom>&apos;negative regulation of neuron apoptotic process&apos; SubClassOf &apos;negative regulation of neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043525</classIRI>
<classLabel>positive regulation of neuron apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation of neuron apoptotic process&apos; SubClassOf &apos;positive regulation of neuron death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031566</classIRI>
<classLabel>actomyosin contractile ring maintenance</classLabel>
<deletedAxiom>&apos;actomyosin contractile ring maintenance&apos; SubClassOf &apos;contractile ring maintenance&apos;</deletedAxiom>
<newAxiom>&apos;actomyosin contractile ring maintenance&apos; SubClassOf &apos;cellular component maintenance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006417</classIRI>
<classLabel>regulation of translation</classLabel>
<deletedAxiom>&apos;regulation of translation&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of translation&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006457</classIRI>
<classLabel>protein folding</classLabel>
<newAxiom>&apos;protein folding&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein maturation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070997</classIRI>
<classLabel>neuron death</classLabel>
<deletedAxiom>&apos;neuron death&apos; SubClassOf &apos;cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021919</classIRI>
<classLabel>BMP signaling pathway involved in spinal cord dorsal/ventral patterning</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in spinal cord dorsal/ventral patterning&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;spinal cord dorsal/ventral patterning&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in spinal cord dorsal/ventral patterning&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in spinal cord dorsal/ventral patterning&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;spinal cord dorsal/ventral patterning&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021938</classIRI>
<classLabel>smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation</classLabel>
<deletedAxiom>&apos;smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021943</classIRI>
<classLabel>formation of radial glial scaffolds</classLabel>
<deletedAxiom>&apos;formation of radial glial scaffolds&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;formation of radial glial scaffolds&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102158</classIRI>
<classLabel>obsolete very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity</classLabel>
<newAxiom>&apos;obsolete very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity&apos; SubClassOf &apos;3-hydroxyacyl-CoA dehydratase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006351</classIRI>
<classLabel>DNA-templated transcription</classLabel>
<newAxiom>&apos;DNA-templated transcription&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031346</classIRI>
<classLabel>positive regulation of cell projection organization</classLabel>
<newAxiom>&apos;positive regulation of cell projection organization&apos; SubClassOf &apos;positive regulation of cell population proliferation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031345</classIRI>
<classLabel>negative regulation of cell projection organization</classLabel>
<newAxiom>&apos;negative regulation of cell projection organization&apos; SubClassOf &apos;negative regulation of cell population proliferation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006390</classIRI>
<classLabel>mitochondrial transcription</classLabel>
<newAxiom>&apos;mitochondrial transcription&apos; EquivalentTo &apos;DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;mitochondrion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031344</classIRI>
<classLabel>regulation of cell projection organization</classLabel>
<newAxiom>&apos;regulation of cell projection organization&apos; SubClassOf &apos;regulation of cell population proliferation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070930</classIRI>
<classLabel>trans-translation-dependent protein tagging</classLabel>
<deletedAxiom>&apos;trans-translation-dependent protein tagging&apos; SubClassOf &apos;protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;trans-translation-dependent protein tagging&apos; SubClassOf &apos;co-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031262</classIRI>
<classLabel>Ndc80 complex</classLabel>
<deletedAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;Ndc80 complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;outer kinetochore&apos;</deletedAxiom>
<newAxiom>&apos;Ndc80 complex&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180019</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080092</classIRI>
<classLabel>regulation of pollen tube growth</classLabel>
<deletedAxiom>&apos;regulation of pollen tube growth&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021707</classIRI>
<classLabel>cerebellar granule cell differentiation</classLabel>
<newAxiom>&apos;cerebellar granule cell differentiation&apos; SubClassOf &apos;glutamatergic neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045725</classIRI>
<classLabel>positive regulation of glycogen biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycogen biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045727</classIRI>
<classLabel>positive regulation of translation</classLabel>
<deletedAxiom>&apos;positive regulation of translation&apos; SubClassOf &apos;positive regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of translation&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021773</classIRI>
<classLabel>striatal medium spiny neuron differentiation</classLabel>
<newAxiom>&apos;striatal medium spiny neuron differentiation&apos; SubClassOf &apos;GABAergic neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031056</classIRI>
<classLabel>regulation of histone modification</classLabel>
<deletedAxiom>&apos;regulation of histone modification&apos; SubClassOf &apos;regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of histone modification&apos; SubClassOf &apos;regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031062</classIRI>
<classLabel>positive regulation of histone methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone methylation&apos; SubClassOf &apos;positive regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of histone methylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031065</classIRI>
<classLabel>positive regulation of histone deacetylation</classLabel>
<newAxiom>&apos;positive regulation of histone deacetylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031064</classIRI>
<classLabel>negative regulation of histone deacetylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone deacetylation&apos; SubClassOf &apos;negative regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of histone deacetylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031061</classIRI>
<classLabel>negative regulation of histone methylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone methylation&apos; SubClassOf &apos;negative regulation of protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of histone methylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070647</classIRI>
<classLabel>protein modification by small protein conjugation or removal</classLabel>
<deletedAxiom>&apos;protein modification by small protein conjugation or removal&apos; SubClassOf &apos;protein modification process&apos;</deletedAxiom>
<newAxiom>&apos;protein modification by small protein conjugation or removal&apos; SubClassOf &apos;post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008608</classIRI>
<classLabel>attachment of spindle microtubules to kinetochore</classLabel>
<deletedAxiom>&apos;attachment of spindle microtubules to kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nuclear chromosome segregation&apos;</deletedAxiom>
<newAxiom>&apos;attachment of spindle microtubules to kinetochore&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;metaphase plate congression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033656</classIRI>
<classLabel>modification by symbiont of host chloroplast</classLabel>
<deletedAxiom>&apos;modification by symbiont of host chloroplast&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host chloroplast&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033659</classIRI>
<classLabel>modification by symbiont of host mitochondrion</classLabel>
<deletedAxiom>&apos;modification by symbiont of host mitochondrion&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host mitochondrion&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008553</classIRI>
<classLabel>P-type proton-exporting transporter activity</classLabel>
<deletedAxiom>&apos;P-type proton-exporting transporter activity&apos; SubClassOf &apos;pyrophosphate hydrolysis-driven proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;P-type proton-exporting transporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070309</classIRI>
<classLabel>lens fiber cell morphogenesis</classLabel>
<deletedAxiom>&apos;lens fiber cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;lens fiber cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060902</classIRI>
<classLabel>regulation of hair cycle by BMP signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of hair cycle by BMP signaling pathway&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of hair cycle by BMP signaling pathway&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;hair cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of hair cycle by BMP signaling pathway&apos; SubClassOf &apos;regulation of hair cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060822</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;axial mesodermal cell fate specification&apos;)</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;axial mesodermal cell fate specification&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060826</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neural plate anterior/posterior regionalization&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neural plate anterior/posterior regionalization&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060835</classIRI>
<classLabel>transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification</classLabel>
<deletedAxiom>&apos;transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;oral/aboral axis specification&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;oral/aboral axis specification&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035893</classIRI>
<classLabel>negative regulation of platelet aggregation in another organism</classLabel>
<deletedAxiom>&apos;negative regulation of platelet aggregation in another organism&apos; SubClassOf &apos;negative regulation of platelet aggregation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035894</classIRI>
<classLabel>positive regulation of platelet aggregation in another organism</classLabel>
<deletedAxiom>&apos;positive regulation of platelet aggregation in another organism&apos; SubClassOf &apos;positive regulation of platelet aggregation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060803</classIRI>
<classLabel>BMP signaling pathway involved in mesodermal cell fate specification</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in mesodermal cell fate specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesodermal cell fate specification&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in mesodermal cell fate specification&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesodermal cell fate specification&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in mesodermal cell fate specification&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060804</classIRI>
<classLabel>positive regulation of Wnt signaling pathway by BMP signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of Wnt signaling pathway by BMP signaling pathway&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt signaling pathway by BMP signaling pathway&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;Wnt signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt signaling pathway by BMP signaling pathway&apos; SubClassOf &apos;positive regulation of Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060819</classIRI>
<classLabel>inactivation of X chromosome by genomic imprinting</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;regulation of gene expression by genomic imprinting&apos;</deletedAxiom>
<newAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;genomic imprinting&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035899</classIRI>
<classLabel>negative regulation of blood coagulation in another organism</classLabel>
<deletedAxiom>&apos;negative regulation of blood coagulation in another organism&apos; SubClassOf &apos;negative regulation of blood coagulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060880</classIRI>
<classLabel>cell morphogenesis involved in semicircular canal fusion</classLabel>
<deletedAxiom>&apos;cell morphogenesis involved in semicircular canal fusion&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;cell morphogenesis involved in semicircular canal fusion&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141042</classIRI>
<classLabel>cAMP intoxication in host</classLabel>
<deletedAxiom>&apos;cAMP intoxication in host&apos; SubClassOf &apos;disruption of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;cAMP intoxication in host&apos; SubClassOf &apos;modulation by symbiont of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035806</classIRI>
<classLabel>modulation of blood coagulation in another organism</classLabel>
<deletedAxiom>&apos;modulation of blood coagulation in another organism&apos; SubClassOf &apos;regulation of blood coagulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035807</classIRI>
<classLabel>positive regulation of blood coagulation in another organism</classLabel>
<deletedAxiom>&apos;positive regulation of blood coagulation in another organism&apos; SubClassOf &apos;positive regulation of blood coagulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060724</classIRI>
<classLabel>coreceptor activity involved in epidermal growth factor receptor signaling pathway</classLabel>
<deletedAxiom>&apos;coreceptor activity involved in epidermal growth factor receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;epidermal growth factor receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in epidermal growth factor receptor signaling pathway&apos; EquivalentTo &apos;coreceptor activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;epidermal growth factor receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in epidermal growth factor receptor signaling pathway&apos; SubClassOf &apos;coreceptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060783</classIRI>
<classLabel>mesenchymal smoothened signaling pathway involved in prostate gland development</classLabel>
<deletedAxiom>&apos;mesenchymal smoothened signaling pathway involved in prostate gland development&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033173</classIRI>
<classLabel>calcineurin-NFAT signaling cascade</classLabel>
<deletedAxiom>&apos;calcineurin-NFAT signaling cascade&apos; SubClassOf &apos;inositol phosphate-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060798</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesodermal cell fate specification&apos;)</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesodermal cell fate specification&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060799</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endodermal cell fate specification&apos;)</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endodermal cell fate specification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060797</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell fate commitment involved in formation of primary germ layer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060622</classIRI>
<classLabel>regulation of ascospore wall beta-glucan biosynthetic process</classLabel>
<newAxiom>&apos;regulation of ascospore wall beta-glucan biosynthetic process&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033039</classIRI>
<classLabel>salty taste receptor activity</classLabel>
<deletedAxiom>&apos;salty taste receptor activity&apos; SubClassOf &apos;taste receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;salty taste receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;detection of chemical stimulus involved in sensory perception of salty taste&apos;</deletedAxiom>
<newAxiom>&apos;salty taste receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170021</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045052</classIRI>
<classLabel>protein insertion into ER membrane by GPI attachment sequence</classLabel>
<deletedAxiom>&apos;protein insertion into ER membrane by GPI attachment sequence&apos; SubClassOf &apos;protein insertion into ER membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060506</classIRI>
<classLabel>smoothened signaling pathway involved in lung development</classLabel>
<deletedAxiom>&apos;smoothened signaling pathway involved in lung development&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060507</classIRI>
<classLabel>epidermal growth factor receptor signaling pathway involved in lung development</classLabel>
<deletedAxiom>&apos;epidermal growth factor receptor signaling pathway involved in lung development&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060499</classIRI>
<classLabel>fibroblast growth factor receptor signaling pathway involved in lung induction</classLabel>
<deletedAxiom>&apos;fibroblast growth factor receptor signaling pathway involved in lung induction&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035464</classIRI>
<classLabel>regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulation of transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035463</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060408</classIRI>
<classLabel>regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine metabolic process&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060394</classIRI>
<classLabel>negative regulation of pathway-restricted SMAD protein phosphorylation</classLabel>
<deletedAxiom>&apos;negative regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;pathway-restricted SMAD protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;negative regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of pathway-restricted SMAD protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;pathway-restricted SMAD protein phosphorylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;regulation of pathway-restricted SMAD protein phosphorylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060393</classIRI>
<classLabel>regulation of pathway-restricted SMAD protein phosphorylation</classLabel>
<deletedAxiom>&apos;regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;regulation of protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of pathway-restricted SMAD protein phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;pathway-restricted SMAD protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of pathway-restricted SMAD protein phosphorylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;pathway-restricted SMAD protein phosphorylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060389</classIRI>
<classLabel>pathway-restricted SMAD protein phosphorylation</classLabel>
<deletedAxiom>&apos;pathway-restricted SMAD protein phosphorylation&apos; SubClassOf &apos;protein phosphorylation&apos;</deletedAxiom>
<deletedAxiom>&apos;pathway-restricted SMAD protein phosphorylation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098994</classIRI>
<classLabel>disruption of host cell envelope during viral entry</classLabel>
<deletedAxiom>&apos;disruption of host cell envelope during viral entry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption of host cell envelope during viral entry&apos; EquivalentTo &apos;disruption by symbiont of host cell envelope&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098995</classIRI>
<classLabel>disruption by virus of host envelope lipopolysaccharide during virus entry</classLabel>
<deletedAxiom>&apos;disruption by virus of host envelope lipopolysaccharide during virus entry&apos; SubClassOf &apos;disruption of host cell envelope during viral entry&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host envelope lipopolysaccharide during virus entry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098996</classIRI>
<classLabel>disruption of host cell glycocalyx during viral entry</classLabel>
<deletedAxiom>&apos;disruption of host cell glycocalyx during viral entry&apos; SubClassOf &apos;disruption of host cell envelope during viral entry&apos;</deletedAxiom>
<newAxiom>&apos;disruption of host cell glycocalyx during viral entry&apos; SubClassOf &apos;disruption by symbiont of host cell envelope&apos;</newAxiom>
<newAxiom>&apos;disruption of host cell glycocalyx during viral entry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035318</classIRI>
<classLabel>imaginal disc-derived wing hair outgrowth</classLabel>
<newAxiom>&apos;imaginal disc-derived wing hair outgrowth&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035319</classIRI>
<classLabel>imaginal disc-derived wing hair elongation</classLabel>
<newAxiom>&apos;imaginal disc-derived wing hair elongation&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035317</classIRI>
<classLabel>imaginal disc-derived wing hair organization</classLabel>
<deletedAxiom>&apos;imaginal disc-derived wing hair organization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;imaginal disc-derived wing morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;imaginal disc-derived wing hair organization&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098932</classIRI>
<classLabel>disruption by virus of host cell wall peptidoglycan during virus entry</classLabel>
<deletedAxiom>&apos;disruption by virus of host cell wall peptidoglycan during virus entry&apos; SubClassOf &apos;disruption of host cell envelope during viral entry&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host cell wall peptidoglycan during virus entry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098933</classIRI>
<classLabel>disruption by symbiont of host cell envelope</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098865</classIRI>
<classLabel>disruption by symbiont of host tight cell-cell junction</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host tight cell-cell junction&apos; SubClassOf &apos;modification by symbiont of host tight cell-cell junction&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host tight cell-cell junction&apos; SubClassOf &apos;modification by symbiont of host cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001831</classIRI>
<classLabel>trophectodermal cellular morphogenesis</classLabel>
<deletedAxiom>&apos;trophectodermal cellular morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;trophectodermal cellular morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001828</classIRI>
<classLabel>inner cell mass cellular morphogenesis</classLabel>
<deletedAxiom>&apos;inner cell mass cellular morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;inner cell mass cellular morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098781</classIRI>
<classLabel>ncRNA transcription</classLabel>
<newAxiom>&apos;ncRNA transcription&apos; SubClassOf &apos;ncRNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072101</classIRI>
<classLabel>specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway</classLabel>
<deletedAxiom>&apos;specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway&apos; SubClassOf &apos;specification of ureteric bud anterior/posterior symmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098745</classIRI>
<classLabel>Dcp1-Dcp2 complex</classLabel>
<deletedAxiom>&apos;Dcp1-Dcp2 complex&apos; SubClassOf &apos;RNA cap binding complex&apos;</deletedAxiom>
<newAxiom>&apos;Dcp1-Dcp2 complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035066</classIRI>
<classLabel>positive regulation of histone acetylation</classLabel>
<newAxiom>&apos;positive regulation of histone acetylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035067</classIRI>
<classLabel>negative regulation of histone acetylation</classLabel>
<newAxiom>&apos;negative regulation of histone acetylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072097</classIRI>
<classLabel>negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway&apos; SubClassOf &apos;negative regulation of branch elongation involved in ureteric bud branching&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;branch elongation involved in ureteric bud branching&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098697</classIRI>
<classLabel>ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels</classLabel>
<deletedAxiom>&apos;ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of postsynaptic cytosolic calcium ion concentration&apos;</deletedAxiom>
<newAxiom>&apos;ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels&apos; SubClassOf &apos;calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905114</classIRI>
<classLabel>cell surface receptor signaling pathway involved in cell-cell signaling</classLabel>
<deletedAxiom>&apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos; EquivalentTo &apos;cell surface receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell-cell signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos; SubClassOf &apos;cell surface receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell-cell signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098508</classIRI>
<classLabel>endothelial to hematopoietic transition</classLabel>
<deletedAxiom>&apos;endothelial to hematopoietic transition&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;endothelial to hematopoietic transition&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905219</classIRI>
<classLabel>regulation of platelet formation</classLabel>
<deletedAxiom>&apos;regulation of platelet formation&apos; SubClassOf &apos;regulation of cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;regulation of platelet formation&apos; SubClassOf &apos;regulation of cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905226</classIRI>
<classLabel>regulation of adhesion of symbiont to host epithelial cell</classLabel>
<deletedAxiom>&apos;regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;adhesion of symbiont to host epithelial cell&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of adhesion of symbiont to host epithelial cell&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;adhesion of symbiont to host epithelial cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf &apos;regulation of biological process involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905227</classIRI>
<classLabel>negative regulation of adhesion of symbiont to host epithelial cell</classLabel>
<deletedAxiom>&apos;negative regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf &apos;regulation of adhesion of symbiont to host epithelial cell&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adhesion of symbiont to host epithelial cell&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;adhesion of symbiont to host epithelial cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;adhesion of symbiont to host epithelial cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905228</classIRI>
<classLabel>positive regulation of adhesion of symbiont to host epithelial cell</classLabel>
<deletedAxiom>&apos;positive regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adhesion of symbiont to host epithelial cell&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;adhesion of symbiont to host epithelial cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;adhesion of symbiont to host epithelial cell&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adhesion of symbiont to host epithelial cell&apos; SubClassOf &apos;regulation of adhesion of symbiont to host epithelial cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905313</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart development&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart development&apos;)</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart development&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart development&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905478</classIRI>
<classLabel>regulation of glutamate-ammonia ligase activity</classLabel>
<deletedAxiom>&apos;regulation of glutamate-ammonia ligase activity&apos; SubClassOf &apos;regulation of ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of glutamate-ammonia ligase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;glutamate-ammonia ligase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of glutamate-ammonia ligase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;glutamate-ammonia ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905479</classIRI>
<classLabel>negative regulation of glutamate-ammonia ligase activity</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate-ammonia ligase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;glutamate-ammonia ligase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate-ammonia ligase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;glutamate-ammonia ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate-ammonia ligase activity&apos; SubClassOf &apos;regulation of glutamate-ammonia ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glutamate-ammonia ligase activity&apos; SubClassOf &apos;negative regulation of ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905480</classIRI>
<classLabel>positive regulation of glutamate-ammonia ligase activity</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate-ammonia ligase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;glutamate-ammonia ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate-ammonia ligase activity&apos; SubClassOf &apos;regulation of glutamate-ammonia ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate-ammonia ligase activity&apos; SubClassOf &apos;positive regulation of ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutamate-ammonia ligase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;glutamate-ammonia ligase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003875</classIRI>
<classLabel>ADP-ribosylarginine hydrolase activity</classLabel>
<newAxiom>&apos;ADP-ribosylarginine hydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001172</classIRI>
<classLabel>RNA-templated transcription</classLabel>
<newAxiom>&apos;RNA-templated transcription&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003700</classIRI>
<classLabel>DNA-binding transcription factor activity</classLabel>
<deletedAxiom>&apos;DNA-binding transcription factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039657</classIRI>
<classLabel>suppression by virus of host gene expression</classLabel>
<deletedAxiom>&apos;suppression by virus of host gene expression&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039644</classIRI>
<classLabel>suppression by virus of host NF-kappaB cascade</classLabel>
<newAxiom>&apos;suppression by virus of host NF-kappaB cascade&apos; SubClassOf &apos;disruption of host I-kappaB kinase/NF-kappaB cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039514</classIRI>
<classLabel>disruption by virus of host JAK-STAT cascade</classLabel>
<deletedAxiom>&apos;disruption by virus of host JAK-STAT cascade&apos; SubClassOf &apos;disruption of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host JAK-STAT cascade&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141075</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039502</classIRI>
<classLabel>suppression by virus of host type I interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141077</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039519</classIRI>
<classLabel>modulation by virus of host autophagy</classLabel>
<deletedAxiom>&apos;modulation by virus of host autophagy&apos; SubClassOf &apos;regulation of autophagic cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host autophagy&apos; SubClassOf &apos;modulation by symbiont of host programmed cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host autophagy&apos; SubClassOf &apos;regulation of autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host autophagy&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;autophagic cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host autophagy&apos; SubClassOf &apos;modulation by symbiont of host autophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039527</classIRI>
<classLabel>disruption by virus of host TRAF-mediated signal transduction</classLabel>
<deletedAxiom>&apos;disruption by virus of host TRAF-mediated signal transduction&apos; SubClassOf &apos;disruption of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host TRAF-mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141076</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039521</classIRI>
<classLabel>suppression by virus of host autophagy</classLabel>
<deletedAxiom>&apos;suppression by virus of host autophagy&apos; SubClassOf &apos;suppression of host autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host autophagy&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;autophagy&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host autophagy&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host autophagy&apos; SubClassOf &apos;modulation by virus of host autophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039520</classIRI>
<classLabel>induction by virus of host autophagy</classLabel>
<newAxiom>&apos;induction by virus of host autophagy&apos; SubClassOf &apos;modulation by symbiont of host autophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003382</classIRI>
<classLabel>epithelial cell morphogenesis</classLabel>
<deletedAxiom>&apos;epithelial cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;epithelial cell morphogenesis&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003434</classIRI>
<classLabel>BMP signaling pathway involved in growth plate cartilage chondrocyte development</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in growth plate cartilage chondrocyte development&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;growth plate cartilage chondrocyte development&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in growth plate cartilage chondrocyte development&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in growth plate cartilage chondrocyte development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;growth plate cartilage chondrocyte development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904789</classIRI>
<classLabel>regulation of mitotic actomyosin contractile ring maintenance</classLabel>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring maintenance&apos; SubClassOf &apos;regulation of actomyosin structure organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring maintenance&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic actomyosin contractile ring maintenance&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring maintenance&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic actomyosin contractile ring maintenance&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring maintenance&apos; SubClassOf &apos;regulation of mitotic cytokinetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904929</classIRI>
<classLabel>coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway</classLabel>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway&apos; EquivalentTo &apos;coreceptor activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Wnt signaling pathway, planar cell polarity pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Wnt signaling pathway, planar cell polarity pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway&apos; SubClassOf &apos;coreceptor activity involved in Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904928</classIRI>
<classLabel>coreceptor activity involved in canonical Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;coreceptor activity involved in canonical Wnt signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in canonical Wnt signaling pathway&apos; EquivalentTo &apos;coreceptor activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;canonical Wnt signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in canonical Wnt signaling pathway&apos; SubClassOf &apos;coreceptor activity involved in Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003269</classIRI>
<classLabel>BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation&apos; EquivalentTo &apos;BMP signaling pathway involved in heart development&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of secondary heart field cardioblast proliferation&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of secondary heart field cardioblast proliferation&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation&apos; SubClassOf &apos;BMP signaling pathway involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001141</classIRI>
<classLabel>regulation of RNA biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of RNA biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003303</classIRI>
<classLabel>BMP signaling pathway involved in heart jogging</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in heart jogging&apos; SubClassOf &apos;BMP signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart jogging&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart jogging&apos; SubClassOf &apos;BMP signaling pathway involved in determination of left/right symmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart jogging&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003302</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway involved in heart jogging</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart jogging&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart jogging&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart jogging&apos; SubClassOf &apos;transforming growth factor beta receptor signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway involved in heart jogging&apos; EquivalentTo &apos;transforming growth factor beta receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart jogging&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990813</classIRI>
<classLabel>meiotic centromeric cohesion protection</classLabel>
<deletedAxiom>&apos;meiotic centromeric cohesion protection&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;monopolar spindle attachment to meiosis I kinetochore&apos;</deletedAxiom>
<newAxiom>&apos;meiotic centromeric cohesion protection&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;homologous chromosome segregation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005845</classIRI>
<classLabel>mRNA cap binding complex</classLabel>
<deletedAxiom>&apos;mRNA cap binding complex&apos; SubClassOf &apos;intracellular protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005846</classIRI>
<classLabel>nuclear cap binding complex</classLabel>
<deletedAxiom>&apos;nuclear cap binding complex&apos; SubClassOf &apos;intracellular protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003155</classIRI>
<classLabel>BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right asymmetry in lateral mesoderm&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;BMP signaling pathway involved in determination of left/right symmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right asymmetry in lateral mesoderm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003154</classIRI>
<classLabel>BMP signaling pathway involved in determination of left/right symmetry</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of left/right symmetry&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of left/right symmetry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in determination of left/right symmetry&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003130</classIRI>
<classLabel>BMP signaling pathway involved in heart induction</classLabel>
<deletedAxiom>&apos;BMP signaling pathway involved in heart induction&apos; EquivalentTo &apos;BMP signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart induction&apos;)</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart induction&apos; SubClassOf &apos;BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart induction&apos; SubClassOf &apos;cell surface receptor signaling pathway involved in cell-cell signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;BMP signaling pathway involved in heart induction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endodermal-mesodermal cell signaling involved in heart induction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902406</classIRI>
<classLabel>mitotic actomyosin contractile ring maintenance</classLabel>
<deletedAxiom>&apos;mitotic actomyosin contractile ring maintenance&apos; SubClassOf &apos;mitotic cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic actomyosin contractile ring maintenance&apos; EquivalentTo &apos;actomyosin contractile ring maintenance&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cell cycle&apos;)</deletedAxiom>
<newAxiom>&apos;mitotic actomyosin contractile ring maintenance&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cytokinesis&apos;</newAxiom>
<newAxiom>&apos;mitotic actomyosin contractile ring maintenance&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042729</classIRI>
<classLabel>DASH complex</classLabel>
<deletedAxiom>&apos;DASH complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;outer kinetochore&apos;</deletedAxiom>
<newAxiom>&apos;DASH complex&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180019</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042793</classIRI>
<classLabel>plastid transcription</classLabel>
<newAxiom>&apos;plastid transcription&apos; EquivalentTo &apos;DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;plastid&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052110</classIRI>
<classLabel>occlusion by symbiont of host vascular system</classLabel>
<deletedAxiom>&apos;occlusion by symbiont of host vascular system&apos; SubClassOf &apos;disruption of anatomical structure in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052111</classIRI>
<classLabel>modification by symbiont of host structure</classLabel>
<deletedAxiom>&apos;modification by symbiont of host structure&apos; SubClassOf &apos;modulation by symbiont of host process&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host structure&apos; SubClassOf &apos;disruption of anatomical structure in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052164</classIRI>
<classLabel>symbiont defense to host-produced reactive oxygen species</classLabel>
<deletedAxiom>&apos;symbiont defense to host-produced reactive oxygen species&apos; SubClassOf &apos;evasion of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;symbiont defense to host-produced reactive oxygen species&apos; SubClassOf &apos;cellular response to oxidative stress&apos;</newAxiom>
<newAxiom>&apos;symbiont defense to host-produced reactive oxygen species&apos; SubClassOf &apos;modulation by symbiont of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052163</classIRI>
<classLabel>symbiont defense to host-produced nitric oxide</classLabel>
<deletedAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;evasion of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;symbiont defense to host-produced reactive oxygen species&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052078</classIRI>
<classLabel>disruption of host pathogen-associated molecular pattern receptor signaling pathway</classLabel>
<deletedAxiom>&apos;disruption of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;modulation by symbiont of host innate immune response MAPK kinase signaling&apos;</deletedAxiom>
<newAxiom>&apos;disruption of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;disruption of host receptor-mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052080</classIRI>
<classLabel>modulation by symbiont of host innate immune response MAPK kinase signaling</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host innate immune response MAPK kinase signaling&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host innate immune response MAPK kinase signaling&apos; SubClassOf &apos;modulation by symbiont of host protein kinase-mediated signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host innate immune response MAPK kinase signaling&apos; SubClassOf &apos;modulation by symbiont of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030713</classIRI>
<classLabel>follicle cell of egg chamber stalk formation</classLabel>
<deletedAxiom>&apos;follicle cell of egg chamber stalk formation&apos; SubClassOf &apos;cell morphogenesis involved in differentiation&apos;</deletedAxiom>
<newAxiom>&apos;follicle cell of egg chamber stalk formation&apos; SubClassOf &apos;cell morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052008</classIRI>
<classLabel>disruption by symbiont of host cellular component</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cellular component&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cellular component&apos; SubClassOf &apos;modification by symbiont of host structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052009</classIRI>
<classLabel>disruption by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cell envelope&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;modification by symbiont of host cell wall&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052020</classIRI>
<classLabel>modification by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell wall&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052025</classIRI>
<classLabel>modification by symbiont of host cell membrane</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell membrane&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;modification by symbiont of host cell membrane&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052035</classIRI>
<classLabel>positive regulation by symbiont of host inflammatory response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host inflammatory response&apos; SubClassOf &apos;modulation by symbiont of host inflammatory response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052043</classIRI>
<classLabel>modification by symbiont of host cellular component</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cellular component&apos; SubClassOf &apos;modification by symbiont of host structure&apos;</deletedAxiom>
<deletedAxiom>&apos;modification by symbiont of host cellular component&apos; SubClassOf &apos;disruption of cellular anatomical structure in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902679</classIRI>
<classLabel>negative regulation of RNA biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of RNA biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140973</classIRI>
<classLabel>positive regulation of AIM2 inflammasome complex assembly</classLabel>
<newAxiom>&apos;positive regulation of AIM2 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141087</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140972</classIRI>
<classLabel>negative regulation of AIM2 inflammasome complex assembly</classLabel>
<newAxiom>&apos;negative regulation of AIM2 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141086</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140971</classIRI>
<classLabel>regulation of AIM2 inflammasome complex assembly</classLabel>
<newAxiom>&apos;regulation of AIM2 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141085</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902680</classIRI>
<classLabel>positive regulation of RNA biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of RNA biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140886</classIRI>
<classLabel>suppression by virus of host interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of cytokine-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;interferon-mediated signaling pathway&apos;)</deletedAxiom>
<newAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141077</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140885</classIRI>
<classLabel>suppression by virus of host type III interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141077</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140884</classIRI>
<classLabel>suppression by virus of host type II interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141077</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902812</classIRI>
<classLabel>regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of BMP signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902814</classIRI>
<classLabel>positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902813</classIRI>
<classLabel>negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;negative regulation of BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900225</classIRI>
<classLabel>regulation of NLRP3 inflammasome complex assembly</classLabel>
<newAxiom>&apos;regulation of NLRP3 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141085</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900226</classIRI>
<classLabel>negative regulation of NLRP3 inflammasome complex assembly</classLabel>
<newAxiom>&apos;negative regulation of NLRP3 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141086</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900227</classIRI>
<classLabel>positive regulation of NLRP3 inflammasome complex assembly</classLabel>
<newAxiom>&apos;positive regulation of NLRP3 inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141087</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902893</classIRI>
<classLabel>regulation of miRNA transcription</classLabel>
<deletedAxiom>&apos;regulation of miRNA transcription&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<newAxiom>&apos;regulation of miRNA transcription&apos; SubClassOf &apos;regulation of ncRNA transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140748</classIRI>
<classLabel>positive regulation of regulation of ascospore wall (1-3)-beta-D-glucan biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of regulation of ascospore wall (1-3)-beta-D-glucan biosynthetic process&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140742</classIRI>
<classLabel>lncRNA transcription</classLabel>
<deletedAxiom>&apos;lncRNA transcription&apos; SubClassOf &apos;ncRNA metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005219</classIRI>
<classLabel>ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;calcium-release channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;calcium-induced calcium release activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005220</classIRI>
<classLabel>inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;inositol phosphate-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044831</classIRI>
<classLabel>modulation by virus of host cytokine production</classLabel>
<newAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140632</classIRI>
<classLabel>canonical inflammasome complex assembly</classLabel>
<newAxiom>&apos;canonical inflammasome complex assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0141084</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019740</classIRI>
<classLabel>nitrogen utilization</classLabel>
<newAxiom>&apos;nitrogen utilization&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141067</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140541</classIRI>
<classLabel>piRNA transcription</classLabel>
<deletedAxiom>&apos;piRNA transcription&apos; SubClassOf &apos;ncRNA metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017148</classIRI>
<classLabel>negative regulation of translation</classLabel>
<deletedAxiom>&apos;negative regulation of translation&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of translation&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140506</classIRI>
<classLabel>endoplasmic reticulum-autophagosome adaptor activity</classLabel>
<deletedAxiom>&apos;endoplasmic reticulum-autophagosome adaptor activity&apos; SubClassOf &apos;protein-membrane adaptor activity&apos;</deletedAxiom>
<newAxiom>&apos;endoplasmic reticulum-autophagosome adaptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170009</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017179</classIRI>
<classLabel>peptidyl-diphthine metabolic process</classLabel>
<deletedAxiom>&apos;peptidyl-diphthine metabolic process&apos; SubClassOf &apos;peptidyl-histidine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017182</classIRI>
<classLabel>peptidyl-diphthamide metabolic process</classLabel>
<deletedAxiom>&apos;peptidyl-diphthamide metabolic process&apos; SubClassOf &apos;peptidyl-histidine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017181</classIRI>
<classLabel>peptidyl-diphthine catabolic process</classLabel>
<deletedAxiom>&apos;peptidyl-diphthine catabolic process&apos; SubClassOf &apos;peptidyl-diphthine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-diphthine catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017180</classIRI>
<classLabel>peptidyl-diphthine biosynthetic process from peptidyl-histidine</classLabel>
<deletedAxiom>&apos;peptidyl-diphthine biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;peptidyl-diphthine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-diphthine biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017184</classIRI>
<classLabel>peptidyl-diphthamide catabolic process</classLabel>
<deletedAxiom>&apos;peptidyl-diphthamide catabolic process&apos; SubClassOf &apos;peptidyl-diphthamide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-diphthamide catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017183</classIRI>
<classLabel>peptidyl-diphthamide biosynthetic process from peptidyl-histidine</classLabel>
<deletedAxiom>&apos;peptidyl-diphthamide biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-diphthamide biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;peptidyl-diphthamide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-diphthamide biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;regulation of cytoplasmic translational elongation&apos;</deletedAxiom>
<newAxiom>&apos;peptidyl-diphthamide biosynthetic process from peptidyl-histidine&apos; SubClassOf &apos;peptidyl-histidine modification&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042133</classIRI>
<classLabel>neurotransmitter metabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140474</classIRI>
<classLabel>mitochondrion-endoplasmic reticulum membrane tether activity</classLabel>
<deletedAxiom>&apos;mitochondrion-endoplasmic reticulum membrane tether activity&apos; SubClassOf &apos;protein-membrane adaptor activity&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrion-endoplasmic reticulum membrane tether activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170009</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032604</classIRI>
<classLabel>granulocyte macrophage colony-stimulating factor production</classLabel>
<newAxiom>&apos;granulocyte macrophage colony-stimulating factor production&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032605</classIRI>
<classLabel>hepatocyte growth factor production</classLabel>
<newAxiom>&apos;hepatocyte growth factor production&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032641</classIRI>
<classLabel>lymphotoxin A production</classLabel>
<newAxiom>&apos;lymphotoxin A production&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044658</classIRI>
<classLabel>pore formation in host plasma membrane</classLabel>
<deletedAxiom>&apos;pore formation in host plasma membrane&apos; SubClassOf &apos;modification by symbiont of host cellular component&apos;</deletedAxiom>
<newAxiom>&apos;pore formation in host plasma membrane&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030030</classIRI>
<classLabel>cell projection organization</classLabel>
<newAxiom>&apos;cell projection organization&apos; SubClassOf &apos;cell population proliferation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140293</classIRI>
<classLabel>ADP-ribosylglutamate hydrolase activity</classLabel>
<newAxiom>&apos;ADP-ribosylglutamate hydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140292</classIRI>
<classLabel>ADP-ribosylserine hydrolase activity</classLabel>
<newAxiom>&apos;ADP-ribosylserine hydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071936</classIRI>
<classLabel>coreceptor activity involved in Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway&apos; SubClassOf &apos;coreceptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;coreceptor activity involved in Wnt signaling pathway&apos; EquivalentTo &apos;coreceptor activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;Wnt signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010908</classIRI>
<classLabel>regulation of heparan sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of heparan sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010909</classIRI>
<classLabel>positive regulation of heparan sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of heparan sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140110</classIRI>
<classLabel>transcription regulator activity</classLabel>
<deletedAxiom>&apos;transcription regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;DNA-templated transcription&apos;</deletedAxiom>
<newAxiom>&apos;transcription regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of DNA-templated transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046961</classIRI>
<classLabel>proton-transporting ATPase activity, rotational mechanism</classLabel>
<deletedAxiom>&apos;proton-transporting ATPase activity, rotational mechanism&apos; SubClassOf &apos;pyrophosphate hydrolysis-driven proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;proton-transporting ATPase activity, rotational mechanism&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160080</classIRI>
<classLabel>ABC-type indole transporter activity</classLabel>
<newAxiom>'ABC-type indole transporter activity' SubClassOf 'ABC-type transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160082</classIRI>
<classLabel>hypoxia-inducible factor-proline dioxygenase activity</classLabel>
<newAxiom>'hypoxia-inducible factor-proline dioxygenase activity' SubClassOf 'peptidyl-proline 4-dioxygenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160081</classIRI>
<classLabel>iodide channel activity</classLabel>
<newAxiom>'iodide channel activity' SubClassOf 'monoatomic anion channel activity'</newAxiom>
<newAxiom>'iodide channel activity' SubClassOf 'iodide transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170007</classIRI>
<classLabel>endoplasmic reticulum-lipid droplet tether activity</classLabel>
<newAxiom>'endoplasmic reticulum-lipid droplet tether activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170009</classIRI>
<classLabel>endoplasmic reticulum-organelle membrane tether activity</classLabel>
<newAxiom>'endoplasmic reticulum-organelle membrane tether activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170021</classIRI>
<classLabel>ionotropic taste receptor activity</classLabel>
<newAxiom>'ionotropic taste receptor activity' SubClassOf 'taste receptor activity'</newAxiom>
<newAxiom>'ionotropic taste receptor activity' SubClassOf 'ligand-gated monoatomic ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170020</classIRI>
<classLabel>ionotropic olfactory receptor activity</classLabel>
<newAxiom>'ionotropic olfactory receptor activity' SubClassOf 'olfactory receptor activity'</newAxiom>
<newAxiom>'ionotropic olfactory receptor activity' SubClassOf 'ligand-gated monoatomic ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170016</classIRI>
<classLabel>endoplasmic reticulum-endosome tether activity</classLabel>
<newAxiom>'endoplasmic reticulum-endosome tether activity' SubClassOf 'endoplasmic reticulum-organelle membrane tether activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170023</classIRI>
<classLabel>ionotropic sweet taste receptor activity</classLabel>
<newAxiom>'ionotropic sweet taste receptor activity' SubClassOf 'ionotropic taste receptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170022</classIRI>
<classLabel>ionotropic bitter taste receptor activity</classLabel>
<newAxiom>'ionotropic bitter taste receptor activity' SubClassOf 'ionotropic taste receptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180021</classIRI>
<classLabel>snRNA 2'-O-ribose methyltransferase activity</classLabel>
<newAxiom>'snRNA 2'-O-ribose methyltransferase activity' SubClassOf 'RNA 2'-O-methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180019</classIRI>
<classLabel>Knl1/Spc105 complex</classLabel>
<newAxiom>'Knl1/Spc105 complex' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'outer kinetochore'</newAxiom>
<newAxiom>'Knl1/Spc105 complex' EquivalentTo 'protein-containing complex' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'outer kinetochore')</newAxiom>
<newAxiom>'Knl1/Spc105 complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180020</classIRI>
<classLabel>membrane bending activity</classLabel>
<newAxiom>'membrane bending activity' SubClassOf 'molecular_function'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141087</classIRI>
<classLabel>positive regulation of inflammasome-mediated signaling pathway</classLabel>
<newAxiom>'positive regulation of inflammasome-mediated signaling pathway' SubClassOf 'positive regulation of pattern recognition receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of inflammasome-mediated signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002213 some 'inflammasome-mediated signaling pathway')</newAxiom>
<newAxiom>'positive regulation of inflammasome-mediated signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some 'inflammasome-mediated signaling pathway'</newAxiom>
<newAxiom>'positive regulation of inflammasome-mediated signaling pathway' SubClassOf 'regulation of inflammasome-mediated signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141086</classIRI>
<classLabel>negative regulation of inflammasome-mediated signaling pathway</classLabel>
<newAxiom>'negative regulation of inflammasome-mediated signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'inflammasome-mediated signaling pathway')</newAxiom>
<newAxiom>'negative regulation of inflammasome-mediated signaling pathway' SubClassOf 'negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway'</newAxiom>
<newAxiom>'negative regulation of inflammasome-mediated signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'inflammasome-mediated signaling pathway'</newAxiom>
<newAxiom>'negative regulation of inflammasome-mediated signaling pathway' SubClassOf 'regulation of inflammasome-mediated signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141085</classIRI>
<classLabel>regulation of inflammasome-mediated signaling pathway</classLabel>
<newAxiom>'regulation of inflammasome-mediated signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some 'inflammasome-mediated signaling pathway'</newAxiom>
<newAxiom>'regulation of inflammasome-mediated signaling pathway' SubClassOf 'regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway'</newAxiom>
<newAxiom>'regulation of inflammasome-mediated signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002211 some 'inflammasome-mediated signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141084</classIRI>
<classLabel>inflammasome-mediated signaling pathway</classLabel>
<newAxiom>'inflammasome-mediated signaling pathway' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'inflammatory response'</newAxiom>
<newAxiom>'inflammasome-mediated signaling pathway' SubClassOf 'cytosolic pattern recognition receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141089</classIRI>
<classLabel>glucose sensor activity</classLabel>
<newAxiom>'glucose sensor activity' SubClassOf 'glucose binding'</newAxiom>
<newAxiom>'glucose sensor activity' SubClassOf 'small molecule sensor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141088</classIRI>
<classLabel>symbiont-mediated activation of host autophagy</classLabel>
<newAxiom>'symbiont-mediated activation of host autophagy' SubClassOf 'symbiont-mediated perturbation of host autophagy'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141083</classIRI>
<classLabel>symbiont-mediated suppression of host reactive oxygen species generation</classLabel>
<newAxiom>'symbiont-mediated suppression of host reactive oxygen species generation' SubClassOf 'symbiont defense to host-produced reactive oxygen species'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141082</classIRI>
<classLabel>symbiont-mediated detoxification of host-generated reactive oxygen species</classLabel>
<newAxiom>'symbiont-mediated detoxification of host-generated reactive oxygen species' SubClassOf 'symbiont defense to host-produced reactive oxygen species'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141081</classIRI>
<classLabel>symbiont-mediated suppression of host inflammasome-mediated signal transduction</classLabel>
<newAxiom>'symbiont-mediated suppression of host inflammasome-mediated signal transduction' SubClassOf 'symbiont-mediated activation of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141080</classIRI>
<classLabel>symbiont-mediated activation of host interferon signaling pathway</classLabel>
<newAxiom>'symbiont-mediated activation of host interferon signaling pathway' SubClassOf 'symbiont-mediated activation of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141076</classIRI>
<classLabel>symbiont-mediated suppression of host TRAF-mediated signal transduction</classLabel>
<newAxiom>'symbiont-mediated suppression of host TRAF-mediated signal transduction' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141075</classIRI>
<classLabel>symbiont-mediated suppression of host JAK-STAT cascade</classLabel>
<newAxiom>'symbiont-mediated suppression of host JAK-STAT cascade' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141074</classIRI>
<classLabel>symbiont-mediated suppression of host cGAS-STING signal transduction</classLabel>
<newAxiom>'symbiont-mediated suppression of host cGAS-STING signal transduction' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141073</classIRI>
<classLabel>disruption by symbiont of host opsonization</classLabel>
<newAxiom>'disruption by symbiont of host opsonization' SubClassOf 'modulation by symbiont of host cellular process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141079</classIRI>
<classLabel>symbiont-mediated activation of host inflammasome-mediated signal transduction</classLabel>
<newAxiom>'symbiont-mediated activation of host inflammasome-mediated signal transduction' SubClassOf 'symbiont-mediated activation of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141078</classIRI>
<classLabel>symbiont-mediated suppression of host RIG-I signaling pathway</classLabel>
<newAxiom>'symbiont-mediated suppression of host RIG-I signaling pathway' SubClassOf 'symbiont-mediated suppression of host receptor-mediated signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141077</classIRI>
<classLabel>suppression of host interferon-mediated signaling pathway</classLabel>
<newAxiom>'suppression of host interferon-mediated signaling pathway' SubClassOf 'negative regulation of cytokine-mediated signaling pathway'</newAxiom>
<newAxiom>'suppression of host interferon-mediated signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'interferon-mediated signaling pathway'</newAxiom>
<newAxiom>'suppression of host interferon-mediated signaling pathway' SubClassOf 'suppression by virus of host innate immune response'</newAxiom>
<newAxiom>'suppression of host interferon-mediated signaling pathway' EquivalentTo 'modulation by virus of host cellular process' and (http://purl.obolibrary.org/obo/RO_0002212 some 'interferon-mediated signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141072</classIRI>
<classLabel>symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway</classLabel>
<newAxiom>'symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141071</classIRI>
<classLabel>symbiont-mediated activation of host MAPK signal transduction pathway</classLabel>
<newAxiom>'symbiont-mediated activation of host MAPK signal transduction pathway' SubClassOf 'symbiont-mediated activation of host signal transduction pathway'</newAxiom>
<newAxiom>'symbiont-mediated activation of host MAPK signal transduction pathway' SubClassOf 'perturbation of host MAPK signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141070</classIRI>
<classLabel>symbiont-mediated suppression of host MAPK signal transduction pathway</classLabel>
<newAxiom>'symbiont-mediated suppression of host MAPK signal transduction pathway' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
<newAxiom>'symbiont-mediated suppression of host MAPK signal transduction pathway' SubClassOf 'perturbation of host MAPK signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141069</classIRI>
<classLabel>receptor ligand inhibitor activity</classLabel>
<newAxiom>'receptor ligand inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141068</classIRI>
<classLabel>autosome genomic imprinting</classLabel>
<newAxiom>'autosome genomic imprinting' SubClassOf 'genomic imprinting'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141067</classIRI>
<classLabel>intracellular nitrogen homeostasis</classLabel>
<newAxiom>'intracellular nitrogen homeostasis' SubClassOf 'intracellular chemical homeostasis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141066</classIRI>
<classLabel>disruption of host extracellular matrix</classLabel>
<newAxiom>'disruption of host extracellular matrix' SubClassOf 'disruption of extracellular matrix of another organism'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>