<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
343
</numberChangedClasses>
<numberNewClasses>
42
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103048</classIRI>
<classLabel>tRNA m2A37 methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA m2A37 methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022839</classIRI>
<classLabel>monoatomic ion gated channel activity</classLabel>
<deletedAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;monoatomic ion gated channel activity&apos; SubClassOf &apos;ligand-gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022851</classIRI>
<classLabel>GABA-gated chloride ion channel activity</classLabel>
<deletedAxiom>&apos;GABA-gated chloride ion channel activity&apos; SubClassOf &apos;GABA receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019215</classIRI>
<classLabel>intermediate filament binding</classLabel>
<deletedAxiom>&apos;intermediate filament binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<newAxiom>&apos;intermediate filament binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007250</classIRI>
<classLabel>activation of NF-kappaB-inducing kinase activity</classLabel>
<deletedAxiom>&apos;activation of NF-kappaB-inducing kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;NF-kappaB-inducing kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;activation of NF-kappaB-inducing kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;NF-kappaB-inducing kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007269</classIRI>
<classLabel>neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;neurotransmitter secretion&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007179</classIRI>
<classLabel>transforming growth factor beta receptor signaling pathway</classLabel>
<deletedAxiom>&apos;transforming growth factor beta receptor signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;transforming growth factor beta receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046775</classIRI>
<classLabel>suppression by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046774</classIRI>
<classLabel>suppression by virus of host intracellular interferon activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host intracellular interferon activity&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010723</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to iron</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007105</classIRI>
<classLabel>cytokinesis, division site positioning</classLabel>
<deletedAxiom>&apos;cytokinesis, division site positioning&apos; SubClassOf &apos;contractile ring localization&apos;</deletedAxiom>
<newAxiom>&apos;cytokinesis, division site positioning&apos; SubClassOf &apos;cytokinetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007073</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007072</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;exit from mitosis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;exit from mitosis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007075</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007074</classIRI>
<classLabel>positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter&apos; SubClassOf &apos;positive regulation of transcription involved in exit from mitosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019050</classIRI>
<classLabel>suppression by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;suppression by symbiont of host apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host apoptotic process&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;apoptotic process&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019051</classIRI>
<classLabel>induction by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;positive regulation by symbiont of host apoptotic process&apos;</deletedAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;apoptotic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019071</classIRI>
<classLabel>viral DNA cleavage involved in viral genome maturation</classLabel>
<deletedAxiom>&apos;viral DNA cleavage involved in viral genome maturation&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<newAxiom>&apos;viral DNA cleavage involved in viral genome maturation&apos; SubClassOf &apos;DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044081</classIRI>
<classLabel>symbiont-mediated suppression of host nitric oxide-mediated signaling</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host nitric oxide-mediated signaling&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034617</classIRI>
<classLabel>tetrahydrobiopterin binding</classLabel>
<deletedAxiom>&apos;tetrahydrobiopterin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010672</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010673</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010674</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034517</classIRI>
<classLabel>ribophagy</classLabel>
<deletedAxiom>&apos;ribophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;ribophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061912</classIRI>
<classLabel>selective autophagy</classLabel>
<deletedAxiom>&apos;selective autophagy&apos; SubClassOf &apos;macroautophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061903</classIRI>
<classLabel>positive regulation of 1-phosphatidylinositol-3-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-3-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046333</classIRI>
<classLabel>octopamine metabolic process</classLabel>
<deletedAxiom>&apos;octopamine metabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046334</classIRI>
<classLabel>octopamine catabolic process</classLabel>
<deletedAxiom>&apos;octopamine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061816</classIRI>
<classLabel>proteaphagy</classLabel>
<deletedAxiom>&apos;proteaphagy&apos; SubClassOf &apos;aggrephagy&apos;</deletedAxiom>
<newAxiom>&apos;proteaphagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048718</classIRI>
<classLabel>cibarial fish-trap bristle morphogenesis</classLabel>
<deletedAxiom>&apos;cibarial fish-trap bristle morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061723</classIRI>
<classLabel>glycophagy</classLabel>
<deletedAxiom>&apos;glycophagy&apos; SubClassOf &apos;glycogen catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glycophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;glycophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061726</classIRI>
<classLabel>mitochondrion disassembly</classLabel>
<deletedAxiom>&apos;mitochondrion disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion disassembly&apos; SubClassOf &apos;mitochondrion organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061724</classIRI>
<classLabel>lipophagy</classLabel>
<deletedAxiom>&apos;lipophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;lipophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061709</classIRI>
<classLabel>reticulophagy</classLabel>
<deletedAxiom>&apos;reticulophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;reticulophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061738</classIRI>
<classLabel>late endosomal microautophagy</classLabel>
<deletedAxiom>&apos;late endosomal microautophagy&apos; SubClassOf &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;late endosomal microautophagy&apos; SubClassOf &apos;lysosomal microautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061797</classIRI>
<classLabel>pH-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009019</classIRI>
<classLabel>tRNA (guanine-N1-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine-N1-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009020</classIRI>
<classLabel>tRNA (guanosine-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA 2&apos;-O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048612</classIRI>
<classLabel>post-embryonic ectodermal digestive tract development</classLabel>
<deletedAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ectodermal digestive tract development&apos;</deletedAxiom>
<newAxiom>&apos;post-embryonic ectodermal digestive tract development&apos; SubClassOf &apos;ectodermal digestive tract development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009048</classIRI>
<classLabel>dosage compensation by inactivation of X chromosome</classLabel>
<newAxiom>&apos;dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;heterochromatin formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097603</classIRI>
<classLabel>temperature-gated ion channel activity</classLabel>
<deletedAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
<newAxiom>&apos;temperature-gated ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034054</classIRI>
<classLabel>suppression by symbiont of host defense-related programmed cell death</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host defense-related programmed cell death&apos; SubClassOf &apos;negative regulation of programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036524</classIRI>
<classLabel>protein deglycase activity</classLabel>
<deletedAxiom>&apos;protein deglycase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein deglycase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048563</classIRI>
<classLabel>post-embryonic animal organ morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf &apos;post-embryonic animal morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;post-embryonic animal organ morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048569</classIRI>
<classLabel>post-embryonic animal organ development</classLabel>
<deletedAxiom>&apos;post-embryonic animal organ development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061542</classIRI>
<classLabel>3-demethylubiquinol-n 3-O-methyltransferase activity</classLabel>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097457</classIRI>
<classLabel>hippocampal mossy fiber</classLabel>
<deletedAxiom>&apos;hippocampal mossy fiber&apos; SubClassOf &apos;dentate gyrus mossy fiber&apos;</deletedAxiom>
<newAxiom>&apos;hippocampal mossy fiber&apos; SubClassOf &apos;axon&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061419</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to hypoxia</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000425</classIRI>
<classLabel>pexophagy</classLabel>
<deletedAxiom>&apos;pexophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;pexophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000422</classIRI>
<classLabel>autophagy of mitochondrion</classLabel>
<deletedAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;mitochondrion disassembly&apos;</deletedAxiom>
<newAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;organelle disassembly&apos;</newAxiom>
<newAxiom>&apos;autophagy of mitochondrion&apos; SubClassOf &apos;mitochondrion organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000423</classIRI>
<classLabel>mitophagy</classLabel>
<deletedAxiom>&apos;mitophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;mitophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160079</classIRI>
<classLabel>metabotropic glycine receptor activity</classLabel>
<deletedAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;transmembrane signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;neurotransmitter receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;metabotropic glycine receptor activity&apos; SubClassOf &apos;G protein-coupled neurotransmitter receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097247</classIRI>
<classLabel>epigallocatechin 3-gallate binding</classLabel>
<deletedAxiom>&apos;epigallocatechin 3-gallate binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904081</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000714</classIRI>
<classLabel>positive regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;positive regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000712</classIRI>
<classLabel>regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000713</classIRI>
<classLabel>negative regulation of maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;negative regulation of maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;regulation of maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;maintenance of meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036214</classIRI>
<classLabel>contractile ring localization</classLabel>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;localization&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf &apos;cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;contractile ring localization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytoskeleton-dependent cytokinesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051760</classIRI>
<classLabel>meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;meiotic sister chromatid cohesion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051740</classIRI>
<classLabel>ethylene binding</classLabel>
<deletedAxiom>&apos;ethylene binding&apos; SubClassOf &apos;alkene binding&apos;</deletedAxiom>
<newAxiom>&apos;ethylene binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000166</classIRI>
<classLabel>nucleotide binding</classLabel>
<deletedAxiom>&apos;nucleotide binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048050</classIRI>
<classLabel>post-embryonic eye morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic eye morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036091</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000117</classIRI>
<classLabel>regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097019</classIRI>
<classLabel>neurotransmitter receptor catabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor catabolic process&apos; SubClassOf &apos;receptor catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter receptor catabolic process&apos; SubClassOf &apos;neurotransmitter receptor metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990247</classIRI>
<classLabel>N6-methyladenosine-containing RNA binding</classLabel>
<deletedAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf &apos;RNA binding&apos;</deletedAxiom>
<newAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;RNA binding&apos;</newAxiom>
<newAxiom>&apos;N6-methyladenosine-containing RNA binding&apos; SubClassOf &apos;protein-RNA adaptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075528</classIRI>
<classLabel>perturbation by virus of host immune response</classLabel>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;immune response&apos;)</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
<newAxiom>&apos;perturbation by virus of host immune response&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000083</classIRI>
<classLabel>regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051580</classIRI>
<classLabel>regulation of neurotransmitter uptake</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter uptake&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000820</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;smooth muscle cell differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;smooth muscle cell differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990375</classIRI>
<classLabel>baculum development</classLabel>
<deletedAxiom>&apos;baculum development&apos; SubClassOf &apos;bone development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002561</classIRI>
<classLabel>basophil degranulation</classLabel>
<deletedAxiom>&apos;basophil degranulation&apos; SubClassOf &apos;basophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;basophil degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;basophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000763</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;norepinephrine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;norepinephrine biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051378</classIRI>
<classLabel>serotonin binding</classLabel>
<deletedAxiom>&apos;serotonin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051381</classIRI>
<classLabel>histamine binding</classLabel>
<deletedAxiom>&apos;histamine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110129</classIRI>
<classLabel>SHREC2 complex</classLabel>
<deletedAxiom>&apos;SHREC2 complex&apos; SubClassOf &apos;NuRD complex&apos;</deletedAxiom>
<deletedAxiom>&apos;SHREC2 complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;SHREC complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905905</classIRI>
<classLabel>pharyngeal gland morphogenesis</classLabel>
<deletedAxiom>&apos;pharyngeal gland morphogenesis&apos; SubClassOf &apos;gland morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal gland morphogenesis&apos; SubClassOf &apos;anatomical structure morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002281</classIRI>
<classLabel>macrophage activation involved in immune response</classLabel>
<deletedAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf &apos;myeloid cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf &apos;leukocyte activation involved in immune response&apos;</newAxiom>
<newAxiom>&apos;macrophage activation involved in immune response&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;myeloid cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002276</classIRI>
<classLabel>basophil activation involved in immune response</classLabel>
<deletedAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf &apos;myeloid cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf &apos;leukocyte activation involved in immune response&apos;</newAxiom>
<newAxiom>&apos;basophil activation involved in immune response&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;myeloid cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905922</classIRI>
<classLabel>negative regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905923</classIRI>
<classLabel>positive regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905921</classIRI>
<classLabel>regulation of acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acetylcholine biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110041</classIRI>
<classLabel>regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of pharynx morphogenesis&apos; SubClassOf &apos;regulation of anatomical structure morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pharynx morphogenesis&apos; SubClassOf &apos;regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110040</classIRI>
<classLabel>pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;anatomical structure morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;pharynx morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110043</classIRI>
<classLabel>positive regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;positive regulation of pharynx morphogenesis&apos; SubClassOf &apos;positive regulation of developmental process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of pharynx morphogenesis&apos; SubClassOf &apos;positive regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110042</classIRI>
<classLabel>negative regulation of pharynx morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of pharynx morphogenesis&apos; SubClassOf &apos;negative regulation of developmental process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of pharynx morphogenesis&apos; SubClassOf &apos;negative regulation of animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004808</classIRI>
<classLabel>tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038107</classIRI>
<classLabel>nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;nodal signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right symmetry&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903341</classIRI>
<classLabel>regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of macromolecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903343</classIRI>
<classLabel>positive regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;positive regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903342</classIRI>
<classLabel>negative regulation of meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of macromolecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of nucleobase-containing compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of meiotic DNA double-strand break formation&apos; SubClassOf &apos;negative regulation of DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099100</classIRI>
<classLabel>G-protein gated monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;monoatomic cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;G-protein gated monoatomic ion channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099101</classIRI>
<classLabel>G-protein gated potassium channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated potassium channel activity&apos; SubClassOf &apos;G-protein gated monoatomic cation channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075118</classIRI>
<classLabel>perturbation of host G protein-coupled receptor signal transduction pathway</classLabel>
<newAxiom>&apos;perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf &apos;symbiont-mediated activation of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090686</classIRI>
<classLabel>glycine betaine-activated nonselective monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;glycine betaine-activated nonselective monoatomic cation channel activity&apos; SubClassOf &apos;amino-acid betaine transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004704</classIRI>
<classLabel>NF-kappaB-inducing kinase activity</classLabel>
<deletedAxiom>&apos;NF-kappaB-inducing kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;non-canonical NF-kappaB signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;NF-kappaB-inducing kinase activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016719</classIRI>
<classLabel>carotene 7,8-desaturase activity</classLabel>
<deletedAxiom>&apos;carotene 7,8-desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<newAxiom>&apos;carotene 7,8-desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004741</classIRI>
<classLabel>[pyruvate dehydrogenase (lipoamide)] phosphatase activity</classLabel>
<deletedAxiom>&apos;[pyruvate dehydrogenase (lipoamide)] phosphatase activity&apos; SubClassOf &apos;phosphoprotein phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;[pyruvate dehydrogenase (lipoamide)] phosphatase activity&apos; SubClassOf &apos;protein serine/threonine phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002054</classIRI>
<classLabel>nucleobase binding</classLabel>
<deletedAxiom>&apos;nucleobase binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051039</classIRI>
<classLabel>positive regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051038</classIRI>
<classLabel>negative regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in meiotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051037</classIRI>
<classLabel>regulation of transcription involved in meiotic cell cycle</classLabel>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; EquivalentTo &apos;regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription involved in meiotic cell cycle&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038056</classIRI>
<classLabel>negative regulation of BMP signaling pathway by negative regulation of BMP secretion</classLabel>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; SubClassOf &apos;negative regulation of BMP secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; SubClassOf &apos;negative regulation of BMP signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of BMP signaling pathway by negative regulation of BMP secretion&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;BMP signaling pathway&apos;) and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;BMP secretion&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016580</classIRI>
<classLabel>Sin3 complex</classLabel>
<deletedAxiom>&apos;Sin3 complex&apos; SubClassOf &apos;Sin3-type complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903595</classIRI>
<classLabel>positive regulation of histamine secretion by mast cell</classLabel>
<newAxiom>&apos;positive regulation of histamine secretion by mast cell&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016596</classIRI>
<classLabel>thienylcyclohexylpiperidine binding</classLabel>
<deletedAxiom>&apos;thienylcyclohexylpiperidine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903581</classIRI>
<classLabel>regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of basophil degranulation&apos; SubClassOf &apos;regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903583</classIRI>
<classLabel>positive regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of basophil degranulation&apos; SubClassOf &apos;positive regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903582</classIRI>
<classLabel>negative regulation of basophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of basophil degranulation&apos; SubClassOf &apos;negative regulation of leukocyte activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090508</classIRI>
<classLabel>phenylethylamine biosynthetic process involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;phenylethylamine biosynthetic process involved in synaptic transmission&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090507</classIRI>
<classLabel>phenylethylamine metabolic process involved in synaptic transmission</classLabel>
<deletedAxiom>&apos;phenylethylamine metabolic process involved in synaptic transmission&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903702</classIRI>
<classLabel>esophagus development</classLabel>
<deletedAxiom>&apos;esophagus development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;esophagus development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090419</classIRI>
<classLabel>negative regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000073</classIRI>
<classLabel>regulation of cytokinesis, site selection</classLabel>
<deletedAxiom>&apos;regulation of cytokinesis, site selection&apos; SubClassOf &apos;regulation of localization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006990</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endoplasmic reticulum unfolded protein response&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endoplasmic reticulum unfolded protein response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180019</classIRI>
<classLabel>Knl1/Spc105 complex</classLabel>
<deletedAxiom>&apos;Knl1/Spc105 complex&apos; EquivalentTo &apos;protein-containing complex&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;outer kinetochore&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090215</classIRI>
<classLabel>regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090217</classIRI>
<classLabel>negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;negative regulation of lipid kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090216</classIRI>
<classLabel>positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos; SubClassOf &apos;regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090282</classIRI>
<classLabel>positive regulation of transcription involved in G2/M transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G2/M transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G2/M transition of mitotic cell cycle&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102772</classIRI>
<classLabel>sphingolipid long-chain base 4-hydroxylase activity</classLabel>
<deletedAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<newAxiom>&apos;sphingolipid long-chain base 4-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901265</classIRI>
<classLabel>nucleoside phosphate binding</classLabel>
<deletedAxiom>&apos;nucleoside phosphate binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043827</classIRI>
<classLabel>tRNA (adenine-57, 58-N(1)-) methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (adenine-57, 58-N(1)-) methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090172</classIRI>
<classLabel>microtubule cytoskeleton organization involved in homologous chromosome segregation</classLabel>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf &apos;meiotic cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;homologous chromosome segregation&apos;</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; EquivalentTo &apos;microtubule cytoskeleton organization&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;homologous chromosome segregation&apos;)</deletedAxiom>
<deletedAxiom>&apos;microtubule cytoskeleton organization involved in homologous chromosome segregation&apos; SubClassOf &apos;microtubule cytoskeleton organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901363</classIRI>
<classLabel>heterocyclic compound binding</classLabel>
<deletedAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;heterocyclic compound binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016156</classIRI>
<classLabel>fumarate reductase (NADH) activity</classLabel>
<deletedAxiom>&apos;fumarate reductase (NADH) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;fumarate reductase (NADH) activity&apos; SubClassOf &apos;succinate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901522</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to chemical stimulus&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to chemical stimulus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901585</classIRI>
<classLabel>regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of monoatomic ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901586</classIRI>
<classLabel>negative regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901587</classIRI>
<classLabel>positive regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090086</classIRI>
<classLabel>negative regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;negative regulation of protein deubiquitination&apos; SubClassOf &apos;negative regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090085</classIRI>
<classLabel>regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;regulation of protein deubiquitination&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031626</classIRI>
<classLabel>beta-endorphin binding</classLabel>
<deletedAxiom>&apos;beta-endorphin binding&apos; SubClassOf &apos;neurotransmitter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006581</classIRI>
<classLabel>acetylcholine catabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006589</classIRI>
<classLabel>octopamine biosynthetic process</classLabel>
<deletedAxiom>&apos;octopamine biosynthetic process&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043551</classIRI>
<classLabel>regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043552</classIRI>
<classLabel>positive regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;positive regulation of lipid kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043553</classIRI>
<classLabel>negative regulation of phosphatidylinositol 3-kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;negative regulation of lipid kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf &apos;regulation of phosphatidylinositol 3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;1-phosphatidylinositol-3-kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol 3-kinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;1-phosphatidylinositol-3-kinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043544</classIRI>
<classLabel>lipoamide binding</classLabel>
<deletedAxiom>&apos;lipoamide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043546</classIRI>
<classLabel>molybdopterin cofactor binding</classLabel>
<deletedAxiom>&apos;molybdopterin cofactor binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031419</classIRI>
<classLabel>cobalamin binding</classLabel>
<newAxiom>&apos;cobalamin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102189</classIRI>
<classLabel>4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006349</classIRI>
<classLabel>regulation of gene expression by genomic imprinting</classLabel>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; EquivalentTo &apos;epigenetic regulation of gene expression&apos; and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;genomic imprinting&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;genomic imprinting&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of gene expression by genomic imprinting&apos; SubClassOf &apos;epigenetic regulation of gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043310</classIRI>
<classLabel>negative regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of eosinophil degranulation&apos; SubClassOf &apos;negative regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043311</classIRI>
<classLabel>positive regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of eosinophil degranulation&apos; SubClassOf &apos;positive regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043312</classIRI>
<classLabel>neutrophil degranulation</classLabel>
<deletedAxiom>&apos;neutrophil degranulation&apos; SubClassOf &apos;neutrophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;neutrophil degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neutrophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043303</classIRI>
<classLabel>mast cell degranulation</classLabel>
<deletedAxiom>&apos;mast cell degranulation&apos; SubClassOf &apos;mast cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;mast cell degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mast cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043304</classIRI>
<classLabel>regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of mast cell degranulation&apos; SubClassOf &apos;regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043305</classIRI>
<classLabel>negative regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of mast cell degranulation&apos; SubClassOf &apos;negative regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043306</classIRI>
<classLabel>positive regulation of mast cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of mast cell degranulation&apos; SubClassOf &apos;positive regulation of mast cell activation involved in immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043308</classIRI>
<classLabel>eosinophil degranulation</classLabel>
<deletedAxiom>&apos;eosinophil degranulation&apos; SubClassOf &apos;eosinophil activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;eosinophil degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;eosinophil activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043309</classIRI>
<classLabel>regulation of eosinophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of eosinophil degranulation&apos; SubClassOf &apos;regulation of eosinophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043320</classIRI>
<classLabel>natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;natural killer cell degranulation&apos; SubClassOf &apos;natural killer cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;natural killer cell degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;natural killer cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043321</classIRI>
<classLabel>regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of natural killer cell degranulation&apos; SubClassOf &apos;regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043322</classIRI>
<classLabel>negative regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of natural killer cell degranulation&apos; SubClassOf &apos;negative regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043323</classIRI>
<classLabel>positive regulation of natural killer cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of natural killer cell degranulation&apos; SubClassOf &apos;positive regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043313</classIRI>
<classLabel>regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;regulation of neutrophil degranulation&apos; SubClassOf &apos;regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043314</classIRI>
<classLabel>negative regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of neutrophil degranulation&apos; SubClassOf &apos;negative regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043315</classIRI>
<classLabel>positive regulation of neutrophil degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of neutrophil degranulation&apos; SubClassOf &apos;positive regulation of neutrophil activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043316</classIRI>
<classLabel>cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;cytotoxic T cell degranulation&apos; SubClassOf &apos;T cell activation involved in immune response&apos;</deletedAxiom>
<newAxiom>&apos;cytotoxic T cell degranulation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;T cell activation involved in immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043317</classIRI>
<classLabel>regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043318</classIRI>
<classLabel>negative regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;negative regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;negative regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043319</classIRI>
<classLabel>positive regulation of cytotoxic T cell degranulation</classLabel>
<deletedAxiom>&apos;positive regulation of cytotoxic T cell degranulation&apos; SubClassOf &apos;positive regulation of T cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031262</classIRI>
<classLabel>Ndc80 complex</classLabel>
<deletedAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;Knl1/Spc105 complex&apos;</deletedAxiom>
<newAxiom>&apos;Ndc80 complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
<newAxiom>&apos;Ndc80 complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;outer kinetochore&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043282</classIRI>
<classLabel>pharyngeal muscle development</classLabel>
<deletedAxiom>&apos;pharyngeal muscle development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;pharynx development&apos;</deletedAxiom>
<newAxiom>&apos;pharyngeal muscle development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0160093</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021818</classIRI>
<classLabel>modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration</classLabel>
<deletedAxiom>&apos;modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration&apos; SubClassOf &apos;actin cytoskeleton organization&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cell motility involved in cerebral cortex radial glia guided migration&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031210</classIRI>
<classLabel>phosphatidylcholine binding</classLabel>
<deletedAxiom>&apos;phosphatidylcholine binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102040</classIRI>
<classLabel>fumarate reductase (menaquinone)</classLabel>
<deletedAxiom>&apos;fumarate reductase (menaquinone)&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;fumarate reductase (menaquinone)&apos; SubClassOf &apos;succinate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006127</classIRI>
<classLabel>glycerophosphate shuttle</classLabel>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol-3-phosphate dehydrogenase (quinone) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033771</classIRI>
<classLabel>licodione synthase activity</classLabel>
<deletedAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<newAxiom>&apos;licodione synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031077</classIRI>
<classLabel>post-embryonic camera-type eye development</classLabel>
<deletedAxiom>&apos;post-embryonic camera-type eye development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070646</classIRI>
<classLabel>protein modification by small protein removal</classLabel>
<deletedAxiom>&apos;protein modification by small protein removal&apos; SubClassOf &apos;proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031087</classIRI>
<classLabel>deadenylation-independent decapping of nuclear-transcribed mRNA</classLabel>
<deletedAxiom>&apos;deadenylation-independent decapping of nuclear-transcribed mRNA&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008689</classIRI>
<classLabel>3-demethylubiquinone-9 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinone-9 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033668</classIRI>
<classLabel>suppression by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; SubClassOf &apos;negative regulation of apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; SubClassOf &apos;modulation by symbiont of host apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;apoptotic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033657</classIRI>
<classLabel>disruption by symbiont of host chloroplast part</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host chloroplast part&apos; SubClassOf &apos;disruption by symbiont of host chloroplast&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033658</classIRI>
<classLabel>disruption by symbiont of host chloroplast thylakoid</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host chloroplast thylakoid&apos; SubClassOf &apos;disruption by symbiont of host chloroplast part&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host chloroplast thylakoid&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070525</classIRI>
<classLabel>tRNA threonylcarbamoyladenosine metabolic process</classLabel>
<deletedAxiom>&apos;tRNA threonylcarbamoyladenosine metabolic process&apos; SubClassOf &apos;RNA metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;tRNA threonylcarbamoyladenosine metabolic process&apos; SubClassOf &apos;tRNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021510</classIRI>
<classLabel>spinal cord development</classLabel>
<deletedAxiom>&apos;spinal cord development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;spinal cord development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008381</classIRI>
<classLabel>mechanosensitive monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
<newAxiom>&apos;mechanosensitive monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035973</classIRI>
<classLabel>aggrephagy</classLabel>
<deletedAxiom>&apos;aggrephagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;aggrephagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060820</classIRI>
<classLabel>inactivation of X chromosome by heterochromatin formation</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by heterochromatin formation&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of X chromosome by heterochromatin formation&apos; SubClassOf &apos;constitutive heterochromatin formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035876</classIRI>
<classLabel>maintenance of meiotic sister chromatid cohesion, arms</classLabel>
<deletedAxiom>&apos;maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic sister chromatid cohesion, arms&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of meiotic sister chromatid cohesion, arms&apos; SubClassOf &apos;maintenance of meiotic sister chromatid cohesion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045213</classIRI>
<classLabel>neurotransmitter receptor metabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor metabolic process&apos; SubClassOf &apos;receptor metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060819</classIRI>
<classLabel>inactivation of X chromosome by genomic imprinting</classLabel>
<deletedAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;genomic imprinting&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of X chromosome by genomic imprinting&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060817</classIRI>
<classLabel>inactivation of paternal X chromosome</classLabel>
<deletedAxiom>&apos;inactivation of paternal X chromosome&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060818</classIRI>
<classLabel>inactivation of paternal X chromosome by genomic imprinting</classLabel>
<deletedAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;inactivation of paternal X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;inactivation of X chromosome by genomic imprinting&apos;</deletedAxiom>
<newAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;dosage compensation by inactivation of X chromosome&apos;</newAxiom>
<newAxiom>&apos;inactivation of paternal X chromosome by genomic imprinting&apos; SubClassOf &apos;genomic imprinting&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008292</classIRI>
<classLabel>acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;acetylcholine biosynthetic process&apos; SubClassOf &apos;neurotransmitter biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008291</classIRI>
<classLabel>acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine metabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060865</classIRI>
<classLabel>negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; EquivalentTo &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;floral organ abscission&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;regulation of floral organ abscission by signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway&apos; SubClassOf &apos;negative regulation of floral organ abscission&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060869</classIRI>
<classLabel>transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission</classLabel>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf &apos;reproductive process&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;floral organ abscission&apos;</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; EquivalentTo &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;floral organ abscission&apos;)</deletedAxiom>
<deletedAxiom>&apos;transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045253</classIRI>
<classLabel>pyruvate dehydrogenase (lipoamide) phosphatase complex</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (lipoamide) phosphatase complex&apos; SubClassOf &apos;phosphatase complex&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate dehydrogenase (lipoamide) phosphatase complex&apos; SubClassOf &apos;protein serine/threonine phosphatase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033265</classIRI>
<classLabel>choline binding</classLabel>
<deletedAxiom>&apos;choline binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141077</classIRI>
<classLabel>suppression of host interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression of host interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of cytokine-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141066</classIRI>
<classLabel>disruption of host extracellular matrix</classLabel>
<newAxiom>&apos;disruption of host extracellular matrix&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070209</classIRI>
<classLabel>ASTRA complex</classLabel>
<deletedAxiom>&apos;ASTRA complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;TTT complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141006</classIRI>
<classLabel>piRNA-mediated retrotransposon silencing by heterochromatin formation</classLabel>
<newAxiom>&apos;piRNA-mediated retrotransposon silencing by heterochromatin formation&apos; SubClassOf &apos;piRNA-mediated heterochromatin formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141009</classIRI>
<classLabel>piRNA-mediated retrotransposon silencing by mRNA destabilization</classLabel>
<newAxiom>&apos;piRNA-mediated retrotransposon silencing by mRNA destabilization&apos; SubClassOf &apos;piRNA-mediated gene silencing by mRNA destabilization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141014</classIRI>
<classLabel>ribosome hibernation</classLabel>
<deletedAxiom>&apos;ribosome hibernation&apos; SubClassOf &apos;negative regulation of ribosome biogenesis&apos;</deletedAxiom>
<newAxiom>&apos;ribosome hibernation&apos; SubClassOf &apos;negative regulation of translation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008173</classIRI>
<classLabel>RNA methyltransferase activity</classLabel>
<deletedAxiom>&apos;RNA methyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;RNA methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008175</classIRI>
<classLabel>tRNA methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA methyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;tRNA methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008177</classIRI>
<classLabel>succinate dehydrogenase (ubiquinone) activity</classLabel>
<deletedAxiom>&apos;succinate dehydrogenase (ubiquinone) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047780</classIRI>
<classLabel>citrate dehydratase activity</classLabel>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;citrate dehydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;aconitate hydratase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070089</classIRI>
<classLabel>chloride-activated potassium channel activity</classLabel>
<deletedAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;chloride channel activity&apos;</deletedAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
<newAxiom>&apos;chloride-activated potassium channel activity&apos; SubClassOf &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060625</classIRI>
<classLabel>regulation of protein deneddylation</classLabel>
<deletedAxiom>&apos;regulation of protein deneddylation&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047671</classIRI>
<classLabel>anthranilate adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;anthranilate adenylyltransferase activity&apos; SubClassOf &apos;adenylyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;anthranilate adenylyltransferase activity&apos; SubClassOf &apos;acid-amino acid ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072570</classIRI>
<classLabel>ADP-D-ribose binding</classLabel>
<deletedAxiom>&apos;ADP-D-ribose binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106340</classIRI>
<classLabel>tRNA (guanosine 34-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanosine 34-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106339</classIRI>
<classLabel>tRNA (cytidine 32-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine 32-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106335</classIRI>
<classLabel>tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060408</classIRI>
<classLabel>regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;regulation of acetylcholine metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060409</classIRI>
<classLabel>positive regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetylcholine metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060410</classIRI>
<classLabel>negative regulation of acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetylcholine metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050997</classIRI>
<classLabel>quaternary ammonium group binding</classLabel>
<deletedAxiom>&apos;quaternary ammonium group binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;quaternary ammonium group binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098933</classIRI>
<classLabel>disruption by symbiont of host cell envelope</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;modification by symbiont of host cell wall&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cell envelope&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072328</classIRI>
<classLabel>alkene binding</classLabel>
<deletedAxiom>&apos;alkene binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;alkene binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047388</classIRI>
<classLabel>[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase</classLabel>
<deletedAxiom>&apos;[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase&apos; SubClassOf &apos;phosphoric diester hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098864</classIRI>
<classLabel>stabilization of host tight cell-cell junction</classLabel>
<deletedAxiom>&apos;stabilization of host tight cell-cell junction&apos; SubClassOf &apos;disruption of host cell-cell junction&apos;</deletedAxiom>
<newAxiom>&apos;stabilization of host tight cell-cell junction&apos; SubClassOf &apos;disruption of host tight cell-cell junction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050825</classIRI>
<classLabel>ice binding</classLabel>
<deletedAxiom>&apos;ice binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;ice binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050809</classIRI>
<classLabel>diazepam binding</classLabel>
<deletedAxiom>&apos;diazepam binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106059</classIRI>
<classLabel>tRNA (cytidine 56-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine 56-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098792</classIRI>
<classLabel>xenophagy</classLabel>
<deletedAxiom>&apos;xenophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;xenophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060190</classIRI>
<classLabel>negative regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;negative regulation of protein desumoylation&apos; SubClassOf &apos;negative regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060189</classIRI>
<classLabel>positive regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;positive regulation of protein desumoylation&apos; SubClassOf &apos;positive regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060188</classIRI>
<classLabel>regulation of protein desumoylation</classLabel>
<deletedAxiom>&apos;regulation of protein desumoylation&apos; SubClassOf &apos;regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001897</classIRI>
<classLabel>cytolysis by symbiont of host cells</classLabel>
<deletedAxiom>&apos;cytolysis by symbiont of host cells&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;disruption by symbiont of host cell membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001882</classIRI>
<classLabel>nucleoside binding</classLabel>
<deletedAxiom>&apos;nucleoside binding&apos; SubClassOf &apos;small molecule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035126</classIRI>
<classLabel>post-embryonic genitalia morphogenesis</classLabel>
<deletedAxiom>&apos;post-embryonic genitalia morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047151</classIRI>
<classLabel>methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity</classLabel>
<deletedAxiom>&apos;methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035166</classIRI>
<classLabel>post-embryonic hemopoiesis</classLabel>
<deletedAxiom>&apos;post-embryonic hemopoiesis&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098633</classIRI>
<classLabel>collagen fibril binding</classLabel>
<deletedAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
<newAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001695</classIRI>
<classLabel>histamine catabolic process</classLabel>
<deletedAxiom>&apos;histamine catabolic process&apos; SubClassOf &apos;neurotransmitter catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001504</classIRI>
<classLabel>neurotransmitter uptake</classLabel>
<deletedAxiom>&apos;neurotransmitter uptake&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001505</classIRI>
<classLabel>regulation of neurotransmitter levels</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter levels&apos; SubClassOf &apos;regulation of biological quality&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052906</classIRI>
<classLabel>tRNA (guanine(37)-N(1))-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine(37)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanine(37)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052905</classIRI>
<classLabel>tRNA (guanine(9)-N(1))-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine(9)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine-N1-)-methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (guanine(9)-N(1))-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050155</classIRI>
<classLabel>ornithine(lysine) transaminase activity</classLabel>
<deletedAxiom>&apos;ornithine(lysine) transaminase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903003</classIRI>
<classLabel>positive regulation of protein deubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of protein deubiquitination&apos; SubClassOf &apos;positive regulation of proteolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062153</classIRI>
<classLabel>C5-methylcytidine-containing RNA binding</classLabel>
<deletedAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf &apos;RNA binding&apos;</deletedAxiom>
<newAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;RNA binding&apos;</newAxiom>
<newAxiom>&apos;C5-methylcytidine-containing RNA binding&apos; SubClassOf &apos;protein-RNA adaptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905683</classIRI>
<classLabel>peroxisome disassembly</classLabel>
<deletedAxiom>&apos;peroxisome disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisome disassembly&apos; SubClassOf &apos;peroxisome organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039722</classIRI>
<classLabel>suppression by virus of host toll-like receptor signaling pathway</classLabel>
<newAxiom>&apos;suppression by virus of host toll-like receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141105</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904408</classIRI>
<classLabel>melatonin binding</classLabel>
<deletedAxiom>&apos;melatonin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039699</classIRI>
<classLabel>viral mRNA cap methylation</classLabel>
<deletedAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
<newAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052633</classIRI>
<classLabel>isocitrate hydro-lyase (cis-aconitate-forming) activity</classLabel>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;aconitate hydratase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;isocitrate hydro-lyase (cis-aconitate-forming) activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052666</classIRI>
<classLabel>tRNA (cytosine-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytosine-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytosine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062094</classIRI>
<classLabel>stomach development</classLabel>
<deletedAxiom>&apos;stomach development&apos; SubClassOf &apos;animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;stomach development&apos; SubClassOf &apos;anatomical structure development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062093</classIRI>
<classLabel>lysophagy</classLabel>
<deletedAxiom>&apos;lysophagy&apos; SubClassOf &apos;selective autophagy&apos;</deletedAxiom>
<newAxiom>&apos;lysophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039604</classIRI>
<classLabel>suppression by virus of host translation</classLabel>
<deletedAxiom>&apos;suppression by virus of host translation&apos; SubClassOf &apos;suppression by virus of host gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host translation&apos; SubClassOf &apos;induction by virus of catabolism of host mRNA&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039573</classIRI>
<classLabel>suppression by virus of host complement activation</classLabel>
<deletedAxiom>&apos;suppression by virus of host complement activation&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003676</classIRI>
<classLabel>nucleic acid binding</classLabel>
<deletedAxiom>&apos;nucleic acid binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052553</classIRI>
<classLabel>perturbation of host immune response</classLabel>
<newAxiom>&apos;perturbation of host immune response&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052590</classIRI>
<classLabel>sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity</classLabel>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos; SubClassOf &apos;glycerol-3-phosphate dehydrogenase (quinone) activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052591</classIRI>
<classLabel>sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity</classLabel>
<deletedAxiom>&apos;sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity&apos; SubClassOf &apos;sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039503</classIRI>
<classLabel>suppression by virus of host innate immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host innate immune response&apos; SubClassOf &apos;mitigation of host antiviral defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039504</classIRI>
<classLabel>suppression by virus of host adaptive immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;adaptive immune response&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;adaptive immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;perturbation by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039505</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;negative regulation of adaptive immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039502</classIRI>
<classLabel>suppression by virus of host type I interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of type I interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;type I interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039532</classIRI>
<classLabel>negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway&apos; SubClassOf &apos;negative regulation of defense response to virus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039526</classIRI>
<classLabel>modulation by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;modulation by virus of host apoptotic process&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;apoptotic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902097</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;defense response to Gram-negative bacterium&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium&apos; EquivalentTo &apos;positive regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;defense response to Gram-negative bacterium&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990760</classIRI>
<classLabel>osmolarity-sensing monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;osmolarity-sensing monoatomic cation channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;osmolarity-sensing monoatomic cation channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001147</classIRI>
<classLabel>camalexin binding</classLabel>
<deletedAxiom>&apos;camalexin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015277</classIRI>
<classLabel>kainate selective glutamate receptor activity</classLabel>
<deletedAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;sodium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;kainate selective glutamate receptor activity&apos; SubClassOf &apos;ligand-gated sodium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015278</classIRI>
<classLabel>calcium-release channel activity</classLabel>
<deletedAxiom>&apos;calcium-release channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;release of sequestered calcium ion into cytosol&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015276</classIRI>
<classLabel>ligand-gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;ligand-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042729</classIRI>
<classLabel>DASH complex</classLabel>
<deletedAxiom>&apos;DASH complex&apos; SubClassOf &apos;Knl1/Spc105 complex&apos;</deletedAxiom>
<newAxiom>&apos;DASH complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;outer kinetochore&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042783</classIRI>
<classLabel>evasion of host immune response</classLabel>
<deletedAxiom>&apos;evasion of host immune response&apos; SubClassOf &apos;response to host immune response&apos;</deletedAxiom>
<newAxiom>&apos;evasion of host immune response&apos; SubClassOf &apos;perturbation of host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052110</classIRI>
<classLabel>occlusion by symbiont of host vascular system</classLabel>
<deletedAxiom>&apos;occlusion by symbiont of host vascular system&apos; SubClassOf &apos;disruption by symbiont of host anatomical structure&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052112</classIRI>
<classLabel>occlusion by symbiont of host xylem</classLabel>
<deletedAxiom>&apos;occlusion by symbiont of host xylem&apos; SubClassOf &apos;occlusion by symbiont of host vascular system&apos;</deletedAxiom>
<newAxiom>&apos;occlusion by symbiont of host xylem&apos; SubClassOf &apos;disruption by symbiont of host anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052183</classIRI>
<classLabel>disruption of symbiont cellular component</classLabel>
<deletedAxiom>&apos;disruption of symbiont cellular component&apos; SubClassOf &apos;disruption of cellular anatomical structure in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;disruption of symbiont cellular component&apos; SubClassOf &apos;biological process involved in interaction with symbiont&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052150</classIRI>
<classLabel>modulation by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host apoptotic process&apos; SubClassOf &apos;regulation of apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052151</classIRI>
<classLabel>positive regulation by symbiont of host apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; SubClassOf &apos;positive regulation of apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host apoptotic process&apos; SubClassOf &apos;induction by symbiont of host programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052163</classIRI>
<classLabel>symbiont defense to host-produced nitric oxide</classLabel>
<deletedAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;symbiont defense to host-produced reactive oxygen species&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont defense to host-produced nitric oxide&apos; SubClassOf &apos;cellular response to nitrosative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052078</classIRI>
<classLabel>symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902444</classIRI>
<classLabel>riboflavin binding</classLabel>
<deletedAxiom>&apos;riboflavin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052009</classIRI>
<classLabel>disruption by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;modification by symbiont of host cell wall&apos;</deletedAxiom>
<newAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;disruption of cell wall in another organism&apos;</newAxiom>
<newAxiom>&apos;disruption by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030696</classIRI>
<classLabel>tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030697</classIRI>
<classLabel>S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (m5U54) methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (uracil) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030698</classIRI>
<classLabel>5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity</classLabel>
<deletedAxiom>&apos;5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;tRNA (m5U54) methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity&apos; SubClassOf &apos;5,10-methylenetetrahydrofolate-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052020</classIRI>
<classLabel>modification by symbiont of host cell wall</classLabel>
<deletedAxiom>&apos;modification by symbiont of host cell wall&apos; SubClassOf &apos;disruption by symbiont of host cellular component&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0040025</classIRI>
<classLabel>vulval development</classLabel>
<deletedAxiom>&apos;vulval development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
<newAxiom>&apos;vulval development&apos; SubClassOf &apos;animal organ development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052040</classIRI>
<classLabel>modulation by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host programmed cell death&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;programmed cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;programmed cell death&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052042</classIRI>
<classLabel>induction by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;induction by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;programmed cell death&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052041</classIRI>
<classLabel>suppression by symbiont of host programmed cell death</classLabel>
<deletedAxiom>&apos;suppression by symbiont of host programmed cell death&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;programmed cell death&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by symbiont of host programmed cell death&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;programmed cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030509</classIRI>
<classLabel>BMP signaling pathway</classLabel>
<deletedAxiom>&apos;BMP signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;BMP signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030594</classIRI>
<classLabel>neurotransmitter receptor activity</classLabel>
<deletedAxiom>&apos;neurotransmitter receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;neurotransmitter binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005527</classIRI>
<classLabel>macrolide binding</classLabel>
<deletedAxiom>&apos;macrolide binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900095</classIRI>
<classLabel>regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900096</classIRI>
<classLabel>negative regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;negative regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900097</classIRI>
<classLabel>positive regulation of dosage compensation by inactivation of X chromosome</classLabel>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;regulation of dosage compensation by inactivation of X chromosome&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; SubClassOf &apos;positive regulation of chromatin organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of dosage compensation by inactivation of X chromosome&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;dosage compensation by inactivation of X chromosome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140884</classIRI>
<classLabel>suppression by virus of host type II interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of type II interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;type II interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900224</classIRI>
<classLabel>positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;positive regulation of activin receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900164</classIRI>
<classLabel>nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;nodal signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right asymmetry in lateral mesoderm&apos;)</deletedAxiom>
<deletedAxiom>&apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;determination of left/right asymmetry in lateral mesoderm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900175</classIRI>
<classLabel>regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900176</classIRI>
<classLabel>negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry</classLabel>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf &apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900145</classIRI>
<classLabel>regulation of nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900146</classIRI>
<classLabel>negative regulation of nodal signaling pathway involved in determination of left/right asymmetry</classLabel>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of nodal signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of developmental process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nodal signaling pathway involved in determination of left/right asymmetry&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032924</classIRI>
<classLabel>activin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;activin receptor signaling pathway&apos; SubClassOf &apos;transmembrane receptor protein serine/threonine kinase signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;activin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141091</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032979</classIRI>
<classLabel>protein insertion into mitochondrial inner membrane from matrix</classLabel>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;inner mitochondrial membrane organization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140740</classIRI>
<classLabel>ADP-riboxanase activity</classLabel>
<deletedAxiom>&apos;ADP-riboxanase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;post-translational protein modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030398</classIRI>
<classLabel>peroxisomal membrane disassembly</classLabel>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;organelle disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf &apos;membrane disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;peroxisomal membrane disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;autophagy of peroxisome&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005227</classIRI>
<classLabel>calcium activated cation channel activity</classLabel>
<deletedAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;monoatomic cation channel activity&apos;</deletedAxiom>
<newAxiom>&apos;calcium activated cation channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005228</classIRI>
<classLabel>intracellular sodium activated potassium channel activity</classLabel>
<newAxiom>&apos;intracellular sodium activated potassium channel activity&apos; SubClassOf &apos;ligand-gated monoatomic cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044804</classIRI>
<classLabel>nucleophagy</classLabel>
<deletedAxiom>&apos;nucleophagy&apos; SubClassOf &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;nucleophagy&apos; SubClassOf &apos;macroautophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044805</classIRI>
<classLabel>late nucleophagy</classLabel>
<deletedAxiom>&apos;late nucleophagy&apos; SubClassOf &apos;nucleophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005244</classIRI>
<classLabel>voltage-gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;voltage-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;voltage-gated monoatomic ion channel activity&apos; SubClassOf &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044832</classIRI>
<classLabel>induction by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; SubClassOf &apos;regulation of immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030242</classIRI>
<classLabel>autophagy of peroxisome</classLabel>
<deletedAxiom>&apos;autophagy of peroxisome&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;peroxisome disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042166</classIRI>
<classLabel>acetylcholine binding</classLabel>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;neurotransmitter binding&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042165</classIRI>
<classLabel>neurotransmitter binding</classLabel>
<deletedAxiom>&apos;neurotransmitter binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019811</classIRI>
<classLabel>cocaine binding</classLabel>
<deletedAxiom>&apos;cocaine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019726</classIRI>
<classLabel>mevaldate reductase (NADPH) activity</classLabel>
<deletedAxiom>&apos;mevaldate reductase (NADPH) activity&apos; SubClassOf &apos;mevaldate reductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140587</classIRI>
<classLabel>chromatin loop anchoring activity</classLabel>
<newAxiom>&apos;chromatin loop anchoring activity&apos; SubClassOf &apos;chromatin DNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044736</classIRI>
<classLabel>acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;acid-sensing ion channel activity&apos; SubClassOf &apos;ligand-gated sodium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;acid-sensing ion channel activity&apos; SubClassOf &apos;ligand-gated monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005158</classIRI>
<classLabel>insulin receptor binding</classLabel>
<deletedAxiom>&apos;insulin receptor binding&apos; SubClassOf &apos;protein-containing complex binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032777</classIRI>
<classLabel>Piccolo NuA4 histone acetyltransferase complex</classLabel>
<deletedAxiom>&apos;Piccolo NuA4 histone acetyltransferase complex&apos; SubClassOf &apos;NuA4 histone acetyltransferase complex&apos;</deletedAxiom>
<newAxiom>&apos;Piccolo NuA4 histone acetyltransferase complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042138</classIRI>
<classLabel>meiotic DNA double-strand break formation</classLabel>
<deletedAxiom>&apos;meiotic DNA double-strand break formation&apos; SubClassOf &apos;nucleic acid phosphodiester bond hydrolysis&apos;</deletedAxiom>
<newAxiom>&apos;meiotic DNA double-strand break formation&apos; SubClassOf &apos;DNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042137</classIRI>
<classLabel>sequestering of neurotransmitter</classLabel>
<deletedAxiom>&apos;sequestering of neurotransmitter&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042136</classIRI>
<classLabel>neurotransmitter biosynthetic process</classLabel>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter biosynthetic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042135</classIRI>
<classLabel>neurotransmitter catabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;neurotransmitter catabolic process&apos; SubClassOf &apos;neurotransmitter metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042133</classIRI>
<classLabel>neurotransmitter metabolic process</classLabel>
<deletedAxiom>&apos;neurotransmitter metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044689</classIRI>
<classLabel>7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity</classLabel>
<deletedAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity&apos; SubClassOf &apos;ammonia-lyase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044660</classIRI>
<classLabel>viral release via pore formation in host cell membrane</classLabel>
<deletedAxiom>&apos;viral release via pore formation in host cell membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;disruption of plasma membrane integrity in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044658</classIRI>
<classLabel>pore formation in host plasma membrane</classLabel>
<newAxiom>&apos;pore formation in host plasma membrane&apos; SubClassOf &apos;disruption of plasma membrane integrity in another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017041</classIRI>
<classLabel>galactosylgalactosylglucosylceramidase activity</classLabel>
<deletedAxiom>&apos;galactosylgalactosylglucosylceramidase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044673</classIRI>
<classLabel>7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex</classLabel>
<deletedAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex&apos; SubClassOf &apos;transferase complex&apos;</deletedAxiom>
<newAxiom>&apos;7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex&apos; SubClassOf &apos;catalytic complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044596</classIRI>
<classLabel>3-demethylubiquinol-10 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinol-10 3-O-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007504</classIRI>
<classLabel>larval fat body development</classLabel>
<deletedAxiom>&apos;larval fat body development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007508</classIRI>
<classLabel>larval heart development</classLabel>
<deletedAxiom>&apos;larval heart development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140355</classIRI>
<classLabel>cargo receptor ligand activity</classLabel>
<deletedAxiom>&apos;cargo receptor ligand activity&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;cargo receptor ligand activity&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007523</classIRI>
<classLabel>larval visceral muscle development</classLabel>
<deletedAxiom>&apos;larval visceral muscle development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007526</classIRI>
<classLabel>larval somatic muscle development</classLabel>
<deletedAxiom>&apos;larval somatic muscle development&apos; SubClassOf &apos;post-embryonic animal organ development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007560</classIRI>
<classLabel>imaginal disc morphogenesis</classLabel>
<deletedAxiom>&apos;imaginal disc morphogenesis&apos; SubClassOf &apos;post-embryonic animal organ morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;imaginal disc morphogenesis&apos; SubClassOf &apos;animal organ morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140272</classIRI>
<classLabel>exogenous protein binding</classLabel>
<deletedAxiom>&apos;exogenous protein binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;exogenous protein binding&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044414</classIRI>
<classLabel>suppression of host defenses by symbiont</classLabel>
<deletedAxiom>&apos;suppression of host defenses by symbiont&apos; SubClassOf &apos;negative regulation of defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of host defenses by symbiont&apos; SubClassOf &apos;modulation by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044405</classIRI>
<classLabel>detection of host</classLabel>
<deletedAxiom>&apos;detection of host&apos; SubClassOf &apos;detection of other organism&apos;</deletedAxiom>
<deletedAxiom>&apos;detection of host&apos; SubClassOf &apos;response to host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071947</classIRI>
<classLabel>protein deubiquitination involved in ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;protein deubiquitination involved in ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;proteolysis involved in protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071931</classIRI>
<classLabel>positive regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;positive regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;positive regulation of DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071930</classIRI>
<classLabel>negative regulation of transcription involved in G1/S transition of mitotic cell cycle</classLabel>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; EquivalentTo &apos;negative regulation of DNA-templated transcription&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;regulation of transcription involved in G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription involved in G1/S transition of mitotic cell cycle&apos; SubClassOf &apos;negative regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046906</classIRI>
<classLabel>tetrapyrrole binding</classLabel>
<deletedAxiom>&apos;tetrapyrrole binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046928</classIRI>
<classLabel>regulation of neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;regulation of neurotransmitter secretion&apos; SubClassOf &apos;regulation of neurotransmitter levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044302</classIRI>
<classLabel>dentate gyrus mossy fiber</classLabel>
<deletedAxiom>&apos;dentate gyrus mossy fiber&apos; SubClassOf &apos;axon&apos;</deletedAxiom>
<newAxiom>&apos;dentate gyrus mossy fiber&apos; SubClassOf &apos;hippocampal mossy fiber&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160087</classIRI>
<classLabel>spermatid cytoplasm removal during spermiation of flagellated sperm</classLabel>
<newAxiom>'spermatid cytoplasm removal during spermiation of flagellated sperm' SubClassOf 'developmental process involved in reproduction'</newAxiom>
<newAxiom>'spermatid cytoplasm removal during spermiation of flagellated sperm' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'spermatogenesis'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160086</classIRI>
<classLabel>protein localization to polar microtubule</classLabel>
<newAxiom>'protein localization to polar microtubule' SubClassOf 'protein localization to spindle microtubule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160083</classIRI>
<classLabel>exhausted T cell differentiation</classLabel>
<newAxiom>'exhausted T cell differentiation' SubClassOf 'T cell differentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160089</classIRI>
<classLabel>internal N(7)-methylguanine-containing RNA reader activity</classLabel>
<newAxiom>'internal N(7)-methylguanine-containing RNA reader activity' SubClassOf 'protein-RNA adaptor activity'</newAxiom>
<newAxiom>'internal N(7)-methylguanine-containing RNA reader activity' SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some 'RNA binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160091</classIRI>
<classLabel>spliceosome-depend formation of circular RNA</classLabel>
<newAxiom>'spliceosome-depend formation of circular RNA' SubClassOf 'mRNA splicing, via spliceosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160090</classIRI>
<classLabel>internal mRNA (guanine-N7-)-methyltransferase activity</classLabel>
<newAxiom>'internal mRNA (guanine-N7-)-methyltransferase activity' SubClassOf 'mRNA methyltransferase activity'</newAxiom>
<newAxiom>'internal mRNA (guanine-N7-)-methyltransferase activity' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'RNA (guanine-N7)-methylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160097</classIRI>
<classLabel>reverse gyrase activity</classLabel>
<newAxiom>'reverse gyrase activity' SubClassOf 'DNA topoisomerase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160096</classIRI>
<classLabel>nematode pharyngeal muscle development</classLabel>
<newAxiom>'nematode pharyngeal muscle development' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'nematode pharynx development'</newAxiom>
<newAxiom>'nematode pharyngeal muscle development' SubClassOf 'muscle organ development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160095</classIRI>
<classLabel>insect pharynx development</classLabel>
<newAxiom>'insect pharynx development' SubClassOf 'pharynx development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160094</classIRI>
<classLabel>nematode pharynx development</classLabel>
<newAxiom>'nematode pharynx development' SubClassOf 'pharynx development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160093</classIRI>
<classLabel>chordate pharynx development</classLabel>
<newAxiom>'chordate pharynx development' SubClassOf 'pharynx development'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160092</classIRI>
<classLabel>hemozoin formation complex</classLabel>
<newAxiom>'hemozoin formation complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160107</classIRI>
<classLabel>tRNA (adenine(58)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(58)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160106</classIRI>
<classLabel>tRNA (adenine(9)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(9)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160105</classIRI>
<classLabel>tRNA (adenine(22)-N1)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (adenine(22)-N1)-methyltransferase activity' SubClassOf 'tRNA (adenine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160104</classIRI>
<classLabel>tRNA (guanine(26)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160103</classIRI>
<classLabel>tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160102</classIRI>
<classLabel>tRNA (guanine(10)-N2)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-methyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160101</classIRI>
<classLabel>tRNA (guanine(10)-N2)-dimethyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(10)-N2)-dimethyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160109</classIRI>
<classLabel>plant gross anatomical part developmental process</classLabel>
<newAxiom>'plant gross anatomical part developmental process' SubClassOf 'developmental process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160108</classIRI>
<classLabel>animal gross anatomical part developmental process</classLabel>
<newAxiom>'animal gross anatomical part developmental process' SubClassOf 'developmental process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160110</classIRI>
<classLabel>axonemal microtubule doublet inner sheath</classLabel>
<newAxiom>'axonemal microtubule doublet inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal microtubule doublet inner sheath' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal outer doublet'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160115</classIRI>
<classLabel>axonemal microtubule doublet ribbon</classLabel>
<newAxiom>'axonemal microtubule doublet ribbon' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal outer doublet'</newAxiom>
<newAxiom>'axonemal microtubule doublet ribbon' SubClassOf 'cellular anatomical entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160114</classIRI>
<classLabel>axonemal microtubule doublet outer junction</classLabel>
<newAxiom>'axonemal microtubule doublet outer junction' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal microtubule doublet outer junction' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal outer doublet'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160113</classIRI>
<classLabel>axonemal microtubule doublet inner junction</classLabel>
<newAxiom>'axonemal microtubule doublet inner junction' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal microtubule doublet inner junction' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal outer doublet'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160112</classIRI>
<classLabel>axonemal B tubule inner sheath</classLabel>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal microtubule doublet inner sheath'</newAxiom>
<newAxiom>'axonemal B tubule inner sheath' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'A axonemal microtubule'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160111</classIRI>
<classLabel>axonemal A tubule inner sheath</classLabel>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'A axonemal microtubule'</newAxiom>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf 'cellular anatomical entity'</newAxiom>
<newAxiom>'axonemal A tubule inner sheath' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'axonemal microtubule doublet inner sheath'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170027</classIRI>
<classLabel>SKA complex</classLabel>
<newAxiom>'SKA complex' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'outer kinetochore'</newAxiom>
<newAxiom>'SKA complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141105</classIRI>
<classLabel>symbiont-mediated suppression of host toll-like receptor signal transduction</classLabel>
<newAxiom>'symbiont-mediated suppression of host toll-like receptor signal transduction' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141104</classIRI>
<classLabel>symbiont-mediated activation of host G protein-coupled receptor signal transduction</classLabel>
<newAxiom>'symbiont-mediated activation of host G protein-coupled receptor signal transduction' SubClassOf 'perturbation of host G protein-coupled receptor signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141102</classIRI>
<classLabel>tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (uridine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141101</classIRI>
<classLabel>tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity</classLabel>
<newAxiom>'tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity' SubClassOf 'tRNA (uridine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141100</classIRI>
<classLabel>tRNA (guanine(18)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(18)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141098</classIRI>
<classLabel>tRNA (cytidine(34)-2'-O)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (cytidine(34)-2'-O)-methyltransferase activity' SubClassOf 'tRNA (cytidine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141097</classIRI>
<classLabel>ligand-activated transcription activator activity</classLabel>
<newAxiom>'ligand-activated transcription activator activity' SubClassOf 'ligand-activated transcription factor activity'</newAxiom>
<newAxiom>'ligand-activated transcription activator activity' SubClassOf 'DNA-binding transcription activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141096</classIRI>
<classLabel>ligand-activated transcription repressor activity</classLabel>
<newAxiom>'ligand-activated transcription repressor activity' SubClassOf 'ligand-activated transcription factor activity'</newAxiom>
<newAxiom>'ligand-activated transcription repressor activity' SubClassOf 'DNA-binding transcription repressor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141095</classIRI>
<classLabel>retrotransposon silencing by DNA methylation-dependent heterochromatin formation</classLabel>
<newAxiom>'retrotransposon silencing by DNA methylation-dependent heterochromatin formation' SubClassOf 'retrotransposon silencing by heterochromatin formation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141090</classIRI>
<classLabel>protein serine pyrophosphorylase activity</classLabel>
<newAxiom>'protein serine pyrophosphorylase activity' SubClassOf 'phosphotransferase activity, phosphate group as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141094</classIRI>
<classLabel>DNA loop anchor binding</classLabel>
<newAxiom>'DNA loop anchor binding' SubClassOf 'sequence-specific DNA binding'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141093</classIRI>
<classLabel>5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity</classLabel>
<newAxiom>'5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity' SubClassOf 'transferase activity, transferring alkyl or aryl (other than methyl) groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141092</classIRI>
<classLabel>positive regulation of nodal signaling pathway</classLabel>
<newAxiom>'positive regulation of nodal signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002213 some 'nodal signaling pathway')</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some 'nodal signaling pathway'</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf 'regulation of nodal signaling pathway'</newAxiom>
<newAxiom>'positive regulation of nodal signaling pathway' SubClassOf 'positive regulation of activin receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141091</classIRI>
<classLabel>transforming growth factor beta receptor superfamily signaling pathway</classLabel>
<newAxiom>'transforming growth factor beta receptor superfamily signaling pathway' SubClassOf 'transmembrane receptor protein serine/threonine kinase signaling pathway'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>