<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
288
</numberChangedClasses>
<numberNewClasses>
21
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140021</classIRI>
<classLabel>mitochondrial ADP transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial ADP transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022828</classIRI>
<classLabel>phosphorylation-gated channel activity</classLabel>
<deletedAxiom>&apos;phosphorylation-gated channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022859</classIRI>
<classLabel>dephosphorylation-gated channel activity</classLabel>
<deletedAxiom>&apos;dephosphorylation-gated channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022889</classIRI>
<classLabel>serine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;serine transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;serine transport&apos;</deletedAxiom>
<deletedAxiom>&apos;serine transmembrane transporter activity&apos; SubClassOf &apos;neutral L-amino acid transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046775</classIRI>
<classLabel>suppression by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;suppression of host defenses by symbiont&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;suppression by symbiont of host cytokine production&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010723</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to iron</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to iron&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019090</classIRI>
<classLabel>mitochondrial rRNA export from mitochondrion</classLabel>
<newAxiom>&apos;mitochondrial rRNA export from mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071678</classIRI>
<classLabel>olfactory bulb axon guidance</classLabel>
<deletedAxiom>&apos;olfactory bulb axon guidance&apos; SubClassOf &apos;cell proliferation in forebrain&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044075</classIRI>
<classLabel>modulation by symbiont of host vacuole organization</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host vacuole organization&apos; SubClassOf &apos;regulation of vacuole organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044076</classIRI>
<classLabel>positive regulation by symbiont of host vacuole organization</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host vacuole organization&apos; SubClassOf &apos;modulation by symbiont of host vacuole organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host vacuole organization&apos; SubClassOf &apos;positive regulation of vacuole organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034463</classIRI>
<classLabel>90S preribosome assembly</classLabel>
<deletedAxiom>&apos;90S preribosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ribosomal small subunit assembly&apos;</deletedAxiom>
<deletedAxiom>&apos;90S preribosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ribosomal large subunit assembly&apos;</deletedAxiom>
<newAxiom>&apos;90S preribosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytosolic ribosome assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034462</classIRI>
<classLabel>small-subunit processome assembly</classLabel>
<deletedAxiom>&apos;small-subunit processome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ribosomal small subunit assembly&apos;</deletedAxiom>
<newAxiom>&apos;small-subunit processome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0180025</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034471</classIRI>
<classLabel>ncRNA 5&apos;-end processing</classLabel>
<deletedAxiom>&apos;ncRNA 5&apos;-end processing&apos; SubClassOf &apos;RNA capping&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034395</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter in response to iron</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to iron ion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034396</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to iron</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to iron&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to iron&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009255</classIRI>
<classLabel>Entner-Doudoroff pathway through 6-phosphogluconate</classLabel>
<deletedAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf &apos;small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf &apos;glyceraldehyde-3-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048858</classIRI>
<classLabel>cell projection morphogenesis</classLabel>
<deletedAxiom>&apos;cell projection morphogenesis&apos; SubClassOf &apos;cell part morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;cell projection morphogenesis&apos; SubClassOf &apos;cellular component morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034246</classIRI>
<classLabel>mitochondrial transcription factor activity</classLabel>
<deletedAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;DNA-binding transcription factor activity&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial transcription factor activity&apos; SubClassOf &apos;transcription regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061891</classIRI>
<classLabel>calcium ion sensor activity</classLabel>
<deletedAxiom>&apos;calcium ion sensor activity&apos; SubClassOf &apos;calcium ion binding&apos;</deletedAxiom>
<newAxiom>&apos;calcium ion sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;calcium ion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;NADH metabolic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097690</classIRI>
<classLabel>iron ion transmembrane transporter inhibitor activity</classLabel>
<deletedAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
<newAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141110</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009033</classIRI>
<classLabel>trimethylamine-N-oxide reductase activity</classLabel>
<deletedAxiom>&apos;trimethylamine-N-oxide reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;trimethylamine-N-oxide reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009052</classIRI>
<classLabel>pentose-phosphate shunt, non-oxidative branch</classLabel>
<newAxiom>&apos;pentose-phosphate shunt, non-oxidative branch&apos; SubClassOf &apos;ribose phosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;pentose-phosphate shunt, non-oxidative branch&apos; SubClassOf &apos;glyceraldehyde-3-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061611</classIRI>
<classLabel>mannose to fructose-6-phosphate metabolic process</classLabel>
<newAxiom>&apos;mannose to fructose-6-phosphate metabolic process&apos; SubClassOf &apos;fructose 6-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061610</classIRI>
<classLabel>glycerol to glycerone phosphate metabolic process</classLabel>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf &apos;organophosphate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf &apos;carbohydrate derivative metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf &apos;cellular ketone metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf &apos;primary alcohol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<newAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;NAD catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061681</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate&apos; SubClassOf &apos;glyceraldehyde-3-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061680</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde&apos; SubClassOf &apos;monosaccharide metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061678</classIRI>
<classLabel>Entner-Doudoroff pathway</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway&apos; SubClassOf &apos;pyruvate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061502</classIRI>
<classLabel>early endosome to recycling endosome transport</classLabel>
<deletedAxiom>&apos;early endosome to recycling endosome transport&apos; SubClassOf &apos;cytosolic transport&apos;</deletedAxiom>
<newAxiom>&apos;early endosome to recycling endosome transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061541</classIRI>
<classLabel>rhabdomere morphogenesis</classLabel>
<deletedAxiom>&apos;rhabdomere morphogenesis&apos; SubClassOf &apos;cell proliferation involved in compound eye morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000149</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in ventricular septum morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000148</classIRI>
<classLabel>regulation of planar cell polarity pathway involved in ventricular septum morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in ventricular septum morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in ventricular septum morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in ventricular septum morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in heart morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in ventricular septum morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in ventricular septum morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000150</classIRI>
<classLabel>regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in heart morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000151</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000163</classIRI>
<classLabel>regulation of planar cell polarity pathway involved in outflow tract morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in outflow tract morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in outflow tract morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in outflow tract morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in heart morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in outflow tract morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in outflow tract morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000164</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in outflow tract morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000161</classIRI>
<classLabel>regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in heart morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000162</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000168</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in neural tube closure</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in neural tube closure&apos; SubClassOf &apos;negative regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of planar cell polarity pathway involved in neural tube closure&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141113</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000165</classIRI>
<classLabel>regulation of planar cell polarity pathway involved in pericardium morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in pericardium morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in pericardium morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in pericardium morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;planar cell polarity pathway involved in pericardium morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of planar cell polarity pathway involved in pericardium morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in heart morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000166</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in pericardium morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in pericardium morphogenesis&apos; SubClassOf &apos;regulation of planar cell polarity pathway involved in pericardium morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000160</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in heart morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in heart morphogenesis&apos; SubClassOf &apos;negative regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of planar cell polarity pathway involved in heart morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141113</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120286</classIRI>
<classLabel>tryptophan sensor activity</classLabel>
<deletedAxiom>&apos;tryptophan sensor activity&apos; SubClassOf &apos;tryptophan binding&apos;</deletedAxiom>
<newAxiom>&apos;tryptophan sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;tryptophan binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120285</classIRI>
<classLabel>tyrosine sensor activity</classLabel>
<deletedAxiom>&apos;tyrosine sensor activity&apos; SubClassOf &apos;tyrosine binding&apos;</deletedAxiom>
<newAxiom>&apos;tyrosine sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;tyrosine binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061402</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to acidic pH</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to acidic pH&apos; SubClassOf &apos;cellular response to acidic pH&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to acidic pH&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061408</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to heat stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to heat stress&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to heat stress&apos; SubClassOf &apos;cellular response to heat&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061407</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to hydrogen peroxide&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061406</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation&apos; SubClassOf &apos;cellular response to glucose starvation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061411</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to cold</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to cold&apos; SubClassOf &apos;cellular response to cold&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to cold&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061419</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to hypoxia</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061418</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter in response to hypoxia</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to hypoxia&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061417</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061428</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to hypoxia</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to hypoxia&apos; SubClassOf &apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061310</classIRI>
<classLabel>canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cardiac neural crest cell differentiation involved in heart development&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in neural crest cell differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cardiac neural crest cell differentiation involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061315</classIRI>
<classLabel>canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in regulation of cell proliferation&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation&apos; EquivalentTo &apos;canonical Wnt signaling pathway involved in heart development&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cardiac muscle cell proliferation&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cardiac muscle cell proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061324</classIRI>
<classLabel>canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation&apos; SubClassOf &apos;regulation of cell proliferation involved in outflow tract morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in regulation of cell proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097201</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to stress</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061157</classIRI>
<classLabel>mRNA destabilization</classLabel>
<deletedAxiom>&apos;mRNA destabilization&apos; SubClassOf &apos;negative regulation of translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000642</classIRI>
<classLabel>negative regulation of early endosome to late endosome transport</classLabel>
<deletedAxiom>&apos;negative regulation of early endosome to late endosome transport&apos; SubClassOf &apos;negative regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of early endosome to late endosome transport&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000643</classIRI>
<classLabel>positive regulation of early endosome to late endosome transport</classLabel>
<deletedAxiom>&apos;positive regulation of early endosome to late endosome transport&apos; SubClassOf &apos;positive regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of early endosome to late endosome transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904052</classIRI>
<classLabel>negative regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904051</classIRI>
<classLabel>regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904053</classIRI>
<classLabel>positive regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000641</classIRI>
<classLabel>regulation of early endosome to late endosome transport</classLabel>
<deletedAxiom>&apos;regulation of early endosome to late endosome transport&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of early endosome to late endosome transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036086</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036091</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097063</classIRI>
<classLabel>cadmium ion sensor activity</classLabel>
<deletedAxiom>&apos;cadmium ion sensor activity&apos; SubClassOf &apos;cadmium ion binding&apos;</deletedAxiom>
<newAxiom>&apos;cadmium ion sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;cadmium ion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097077</classIRI>
<classLabel>copper ion sensor activity</classLabel>
<deletedAxiom>&apos;copper ion sensor activity&apos; SubClassOf &apos;copper ion binding&apos;</deletedAxiom>
<newAxiom>&apos;copper ion sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;copper ion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036003</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;positive regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904216</classIRI>
<classLabel>positive regulation of protein import into chloroplast stroma</classLabel>
<deletedAxiom>&apos;positive regulation of protein import into chloroplast stroma&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein import into chloroplast stroma&apos; SubClassOf &apos;positive regulation of protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904215</classIRI>
<classLabel>regulation of protein import into chloroplast stroma</classLabel>
<deletedAxiom>&apos;regulation of protein import into chloroplast stroma&apos; SubClassOf &apos;regulation of protein targeting&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein import into chloroplast stroma&apos; SubClassOf &apos;regulation of protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004970</classIRI>
<classLabel>ionotropic glutamate receptor activity</classLabel>
<newAxiom>&apos;ionotropic glutamate receptor activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;ionotropic glutamate receptor activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;ionotropic glutamate receptor activity&apos; SubClassOf &apos;amino acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004993</classIRI>
<classLabel>G protein-coupled serotonin receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor activity&apos; SubClassOf &apos;serotonin receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051204</classIRI>
<classLabel>protein insertion into mitochondrial membrane</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial membrane&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein insertion into mitochondrial membrane&apos; SubClassOf &apos;intracellular protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903215</classIRI>
<classLabel>negative regulation of protein targeting to mitochondrion</classLabel>
<deletedAxiom>&apos;negative regulation of protein targeting to mitochondrion&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004809</classIRI>
<classLabel>tRNA (guanine-N2-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (guanine-N2-)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tRNA (guanine-N2-)-methyltransferase activity&apos; SubClassOf &apos;N-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0089700</classIRI>
<classLabel>protein kinase D signaling</classLabel>
<deletedAxiom>&apos;protein kinase D signaling&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099100</classIRI>
<classLabel>G-protein gated monoatomic cation channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic cation channel activity&apos; SubClassOf &apos;G-protein gated monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099103</classIRI>
<classLabel>channel activator activity</classLabel>
<deletedAxiom>&apos;channel activator activity&apos; SubClassOf &apos;molecular function activator activity&apos;</deletedAxiom>
<newAxiom>&apos;channel activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141109</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099074</classIRI>
<classLabel>mitochondrion to lysosome transport</classLabel>
<deletedAxiom>&apos;mitochondrion to lysosome transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099075</classIRI>
<classLabel>mitochondrion-derived vesicle mediated transport</classLabel>
<newAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099099</classIRI>
<classLabel>G-protein gated monoatomic ion channel activity</classLabel>
<deletedAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;channel activity&apos;</deletedAxiom>
<newAxiom>&apos;G-protein gated monoatomic ion channel activity&apos; SubClassOf &apos;gated channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038031</classIRI>
<classLabel>non-canonical Wnt signaling pathway via JNK cascade</classLabel>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;JNK cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903637</classIRI>
<classLabel>negative regulation of protein insertion into mitochondrial outer membrane</classLabel>
<newAxiom>&apos;negative regulation of protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903636</classIRI>
<classLabel>regulation of protein insertion into mitochondrial outer membrane</classLabel>
<newAxiom>&apos;regulation of protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903638</classIRI>
<classLabel>positive regulation of protein insertion into mitochondrial outer membrane</classLabel>
<newAxiom>&apos;positive regulation of protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016657</classIRI>
<classLabel>oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor</classLabel>
<deletedAxiom>&apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016558</classIRI>
<classLabel>protein import into peroxisome matrix</classLabel>
<deletedAxiom>&apos;protein import into peroxisome matrix&apos; SubClassOf &apos;protein targeting to peroxisome&apos;</deletedAxiom>
<newAxiom>&apos;protein import into peroxisome matrix&apos; SubClassOf &apos;establishment of protein localization to peroxisome&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903533</classIRI>
<classLabel>regulation of protein targeting</classLabel>
<deletedAxiom>&apos;regulation of protein targeting&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of protein targeting&apos; SubClassOf &apos;regulation of establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903570</classIRI>
<classLabel>regulation of protein kinase D signaling</classLabel>
<deletedAxiom>&apos;regulation of protein kinase D signaling&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein kinase D signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein kinase D signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein kinase D signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein kinase D signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903572</classIRI>
<classLabel>positive regulation of protein kinase D signaling</classLabel>
<deletedAxiom>&apos;positive regulation of protein kinase D signaling&apos; SubClassOf &apos;regulation of protein kinase D signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase D signaling&apos; SubClassOf &apos;positive regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase D signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein kinase D signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein kinase D signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein kinase D signaling&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903571</classIRI>
<classLabel>negative regulation of protein kinase D signaling</classLabel>
<deletedAxiom>&apos;negative regulation of protein kinase D signaling&apos; SubClassOf &apos;regulation of protein kinase D signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase D signaling&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein kinase D signaling&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase D signaling&apos; SubClassOf &apos;negative regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of protein kinase D signaling&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein kinase D signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016429</classIRI>
<classLabel>tRNA (adenine-N1)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (adenine-N1)-methyltransferase activity&apos; SubClassOf &apos;tRNA (adenine) methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090375</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090374</classIRI>
<classLabel>oligopeptide export from mitochondrion</classLabel>
<newAxiom>&apos;oligopeptide export from mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000095</classIRI>
<classLabel>regulation of Wnt signaling pathway, planar cell polarity pathway</classLabel>
<deletedAxiom>&apos;regulation of Wnt signaling pathway, planar cell polarity pathway&apos; SubClassOf &apos;regulation of establishment of planar polarity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901229</classIRI>
<classLabel>regulation of non-canonical Wnt signaling pathway via JNK cascade</classLabel>
<deletedAxiom>&apos;regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000057</classIRI>
<classLabel>negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;Wnt signaling pathway involved in digestive tract morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf &apos;regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;Wnt signaling pathway involved in digestive tract morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf &apos;negative regulation of developmental process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf &apos;negative regulation of Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000056</classIRI>
<classLabel>regulation of Wnt signaling pathway involved in digestive tract morphogenesis</classLabel>
<deletedAxiom>&apos;regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf &apos;regulation of Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;Wnt signaling pathway involved in digestive tract morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt signaling pathway involved in digestive tract morphogenesis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;Wnt signaling pathway involved in digestive tract morphogenesis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000041</classIRI>
<classLabel>negative regulation of planar cell polarity pathway involved in axis elongation</classLabel>
<deletedAxiom>&apos;negative regulation of planar cell polarity pathway involved in axis elongation&apos; SubClassOf &apos;negative regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of planar cell polarity pathway involved in axis elongation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141113</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043963</classIRI>
<classLabel>perturbation of host adenylate cyclase-mediated signal transduction</classLabel>
<deletedAxiom>&apos;perturbation of host adenylate cyclase-mediated signal transduction&apos; SubClassOf &apos;perturbation of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043965</classIRI>
<classLabel>symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction&apos; SubClassOf &apos;perturbation of host adenylate cyclase-mediated signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090314</classIRI>
<classLabel>positive regulation of protein targeting to membrane</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to membrane&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein targeting to membrane&apos; SubClassOf &apos;positive regulation of establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090315</classIRI>
<classLabel>negative regulation of protein targeting to membrane</classLabel>
<deletedAxiom>&apos;negative regulation of protein targeting to membrane&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein targeting to membrane&apos; SubClassOf &apos;negative regulation of establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090305</classIRI>
<classLabel>nucleic acid phosphodiester bond hydrolysis</classLabel>
<deletedAxiom>&apos;nucleic acid phosphodiester bond hydrolysis&apos; SubClassOf &apos;nucleic acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903955</classIRI>
<classLabel>positive regulation of protein targeting to mitochondrion</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to mitochondrion&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006877</classIRI>
<classLabel>intracellular cobalt ion homeostasis</classLabel>
<deletedAxiom>&apos;intracellular cobalt ion homeostasis&apos; SubClassOf &apos;cobalt ion homeostasis&apos;</deletedAxiom>
<newAxiom>&apos;intracellular cobalt ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901230</classIRI>
<classLabel>negative regulation of non-canonical Wnt signaling pathway via JNK cascade</classLabel>
<deletedAxiom>&apos;negative regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;regulation of non-canonical Wnt signaling pathway via JNK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;negative regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901231</classIRI>
<classLabel>positive regulation of non-canonical Wnt signaling pathway via JNK cascade</classLabel>
<deletedAxiom>&apos;positive regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;non-canonical Wnt signaling pathway via JNK cascade&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;positive regulation of non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of non-canonical Wnt signaling pathway via JNK cascade&apos; SubClassOf &apos;regulation of non-canonical Wnt signaling pathway via JNK cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901295</classIRI>
<classLabel>regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment</classLabel>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<newAxiom>&apos;regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;regulation of Wnt signaling pathway involved in heart development&apos;</newAxiom>
<newAxiom>&apos;regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901296</classIRI>
<classLabel>negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment</classLabel>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway&apos;</newAxiom>
<newAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;negative regulation of Wnt signaling pathway involved in heart development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901297</classIRI>
<classLabel>positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment</classLabel>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016248</classIRI>
<classLabel>channel inhibitor activity</classLabel>
<deletedAxiom>&apos;channel inhibitor activity&apos; SubClassOf &apos;molecular function inhibitor activity&apos;</deletedAxiom>
<newAxiom>&apos;channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141110</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016247</classIRI>
<classLabel>channel regulator activity</classLabel>
<deletedAxiom>&apos;channel regulator activity&apos; SubClassOf &apos;molecular function regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141108</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0100012</classIRI>
<classLabel>regulation of heart induction by canonical Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of heart induction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by canonical Wnt signaling pathway&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;heart induction&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006839</classIRI>
<classLabel>mitochondrial transport</classLabel>
<deletedAxiom>&apos;mitochondrial transport&apos; SubClassOf &apos;intracellular transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial transport&apos; SubClassOf &apos;transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006850</classIRI>
<classLabel>mitochondrial pyruvate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial pyruvate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006851</classIRI>
<classLabel>mitochondrial calcium ion transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial calcium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006853</classIRI>
<classLabel>carnitine shuttle</classLabel>
<deletedAxiom>&apos;carnitine shuttle&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018847</classIRI>
<classLabel>alpha-pinene lyase activity</classLabel>
<deletedAxiom>&apos;alpha-pinene lyase activity&apos; SubClassOf &apos;intramolecular lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090021</classIRI>
<classLabel>positive regulation of posterior neural plate formation by Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of posterior neural plate formation by Wnt signaling pathway&apos; SubClassOf &apos;regulation of embryonic development&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of posterior neural plate formation by Wnt signaling pathway&apos; SubClassOf &apos;Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of posterior neural plate formation by Wnt signaling pathway&apos; SubClassOf &apos;regulation of animal organ morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of posterior neural plate formation by Wnt signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;posterior neural plate formation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of posterior neural plate formation by Wnt signaling pathway&apos; SubClassOf &apos;positive regulation of developmental process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090082</classIRI>
<classLabel>positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;negative regulation of Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;positive regulation of heart induction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090081</classIRI>
<classLabel>regulation of heart induction by regulation of canonical Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of cell fate specification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of heart induction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; EquivalentTo &apos;regulation of biological process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;regulation of heart induction by canonical Wnt signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of heart induction by regulation of canonical Wnt signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;regulation of heart induction by canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006735</classIRI>
<classLabel>NADH regeneration</classLabel>
<deletedAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;NADH metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043620</classIRI>
<classLabel>regulation of DNA-templated transcription in response to stress</classLabel>
<deletedAxiom>&apos;regulation of DNA-templated transcription in response to stress&apos; SubClassOf &apos;cellular response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of DNA-templated transcription in response to stress&apos; SubClassOf &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043618</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter in response to stress</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;regulation of DNA-templated transcription in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos; SubClassOf &apos;regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043619</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter in response to oxidative stress</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to oxidative stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to oxidative stress&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004050</classIRI>
<classLabel>obsolete apyrase activity</classLabel>
<newAxiom>&apos;obsolete apyrase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006602</classIRI>
<classLabel>creatinine catabolic process</classLabel>
<deletedAxiom>&apos;creatinine catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;creatinine catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006605</classIRI>
<classLabel>protein targeting</classLabel>
<deletedAxiom>&apos;protein targeting&apos; SubClassOf &apos;intracellular protein transport&apos;</deletedAxiom>
<newAxiom>&apos;protein targeting&apos; SubClassOf &apos;establishment of protein localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018600</classIRI>
<classLabel>alpha-pinene dehydrogenase activity</classLabel>
<deletedAxiom>&apos;alpha-pinene dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006623</classIRI>
<classLabel>protein targeting to vacuole</classLabel>
<deletedAxiom>&apos;protein targeting to vacuole&apos; SubClassOf &apos;vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006622</classIRI>
<classLabel>protein targeting to lysosome</classLabel>
<deletedAxiom>&apos;protein targeting to lysosome&apos; SubClassOf &apos;lysosomal transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006625</classIRI>
<classLabel>protein targeting to peroxisome</classLabel>
<deletedAxiom>&apos;protein targeting to peroxisome&apos; SubClassOf &apos;peroxisomal transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006626</classIRI>
<classLabel>protein targeting to mitochondrion</classLabel>
<deletedAxiom>&apos;protein targeting to mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein targeting to mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitochondrion organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006540</classIRI>
<classLabel>glutamate decarboxylation to succinate</classLabel>
<newAxiom>&apos;glutamate decarboxylation to succinate&apos; SubClassOf &apos;succinate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018543</classIRI>
<classLabel>4-amino-2-nitroso-6-nitrotoluene reductase activity</classLabel>
<deletedAxiom>&apos;4-amino-2-nitroso-6-nitrotoluene reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018544</classIRI>
<classLabel>4-carboxy-4&apos;-sulfoazobenzene reductase activity</classLabel>
<deletedAxiom>&apos;4-carboxy-4&apos;-sulfoazobenzene reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018545</classIRI>
<classLabel>NAD(P)H nitroreductase activity</classLabel>
<deletedAxiom>&apos;NAD(P)H nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018595</classIRI>
<classLabel>alpha-pinene monooxygenase activity</classLabel>
<deletedAxiom>&apos;alpha-pinene monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-pinene monooxygenase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018400</classIRI>
<classLabel>peptidyl-proline hydroxylation to 3-hydroxy-L-proline</classLabel>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;heterocycle metabolic process&apos;</newAxiom>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018401</classIRI>
<classLabel>peptidyl-proline hydroxylation to 4-hydroxy-L-proline</classLabel>
<newAxiom>&apos;peptidyl-proline hydroxylation to 4-hydroxy-L-proline&apos; SubClassOf &apos;4-hydroxyproline metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031346</classIRI>
<classLabel>positive regulation of cell projection organization</classLabel>
<deletedAxiom>&apos;positive regulation of cell projection organization&apos; SubClassOf &apos;positive regulation of cell population proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031345</classIRI>
<classLabel>negative regulation of cell projection organization</classLabel>
<deletedAxiom>&apos;negative regulation of cell projection organization&apos; SubClassOf &apos;negative regulation of cell population proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031344</classIRI>
<classLabel>regulation of cell projection organization</classLabel>
<deletedAxiom>&apos;regulation of cell projection organization&apos; SubClassOf &apos;regulation of cell population proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018396</classIRI>
<classLabel>peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine</classLabel>
<newAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070864</classIRI>
<classLabel>sperm individualization complex</classLabel>
<deletedAxiom>&apos;sperm individualization complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;sperm individualization complex&apos; SubClassOf &apos;cellular anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043265</classIRI>
<classLabel>ectoplasm</classLabel>
<deletedAxiom>&apos;ectoplasm&apos; SubClassOf &apos;cellular anatomical entity&apos;</deletedAxiom>
<deletedAxiom>&apos;ectoplasm&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033807</classIRI>
<classLabel>icosanoyl-CoA synthase activity</classLabel>
<deletedAxiom>&apos;icosanoyl-CoA synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045821</classIRI>
<classLabel>positive regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of purine nucleotide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045820</classIRI>
<classLabel>negative regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of purine nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glycolytic process&apos; SubClassOf &apos;negative regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045815</classIRI>
<classLabel>transcription initiation-coupled chromatin remodeling</classLabel>
<deletedAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf &apos;positive regulation of gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf &apos;epigenetic regulation of gene expression&apos;</deletedAxiom>
<newAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf &apos;chromatin remodeling&apos;</newAxiom>
<newAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;transcription initiation at RNA polymerase II promoter&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070832</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline</classLabel>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline&apos; SubClassOf &apos;primary amino compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070834</classIRI>
<classLabel>phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine</classLabel>
<newAxiom>&apos;phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine&apos; SubClassOf &apos;primary amino compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006110</classIRI>
<classLabel>regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of purine nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of glycolytic process&apos; SubClassOf &apos;regulation of ATP metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006116</classIRI>
<classLabel>NADH oxidation</classLabel>
<deletedAxiom>&apos;NADH oxidation&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;NADH oxidation&apos; SubClassOf &apos;NADH metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006127</classIRI>
<classLabel>glycerophosphate shuttle</classLabel>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glycerophosphate shuttle&apos; SubClassOf &apos;organophosphate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043100</classIRI>
<classLabel>pyrimidine nucleobase salvage</classLabel>
<newAxiom>&apos;pyrimidine nucleobase salvage&apos; SubClassOf &apos;pyrimidine nucleobase biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006180</classIRI>
<classLabel>deoxyguanosine salvage</classLabel>
<newAxiom>&apos;deoxyguanosine salvage&apos; SubClassOf &apos;deoxyguanosine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031049</classIRI>
<classLabel>programmed DNA elimination</classLabel>
<deletedAxiom>&apos;programmed DNA elimination&apos; SubClassOf &apos;epigenetic regulation of gene expression&apos;</deletedAxiom>
<newAxiom>&apos;programmed DNA elimination&apos; SubClassOf &apos;negative regulation of gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;pyridine nucleotide catabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;ATP metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic process&apos; SubClassOf &apos;ADP catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055068</classIRI>
<classLabel>cobalt ion homeostasis</classLabel>
<deletedAxiom>&apos;cobalt ion homeostasis&apos; SubClassOf &apos;monoatomic cation homeostasis&apos;</deletedAxiom>
<deletedAxiom>&apos;cobalt ion homeostasis&apos; SubClassOf &apos;inorganic ion homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080007</classIRI>
<classLabel>S-nitrosoglutathione reductase activity</classLabel>
<deletedAxiom>&apos;S-nitrosoglutathione reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;S-nitrosoglutathione reductase activity&apos; SubClassOf &apos;alcohol dehydrogenase (NAD+) activity&apos;</newAxiom>
<newAxiom>&apos;S-nitrosoglutathione reductase activity&apos; SubClassOf &apos;S-(hydroxymethyl)glutathione dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080004</classIRI>
<classLabel>thalian-diol desaturase activity</classLabel>
<deletedAxiom>&apos;thalian-diol desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors&apos;</deletedAxiom>
<newAxiom>&apos;thalian-diol desaturase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008655</classIRI>
<classLabel>pyrimidine-containing compound salvage</classLabel>
<newAxiom>&apos;pyrimidine-containing compound salvage&apos; SubClassOf &apos;pyrimidine-containing compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033569</classIRI>
<classLabel>lactoferrin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;lactoferrin transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;lactoferrin transmembrane transporter activity&apos; SubClassOf &apos;protein transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070584</classIRI>
<classLabel>mitochondrion morphogenesis</classLabel>
<deletedAxiom>&apos;mitochondrion morphogenesis&apos; SubClassOf &apos;cell part morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrion morphogenesis&apos; SubClassOf &apos;mitochondrion organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035991</classIRI>
<classLabel>nitric oxide sensor activity</classLabel>
<deletedAxiom>&apos;nitric oxide sensor activity&apos; SubClassOf &apos;nitric oxide binding&apos;</deletedAxiom>
<newAxiom>&apos;nitric oxide sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;nitric oxide binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035945</classIRI>
<classLabel>mitochondrial ncRNA surveillance</classLabel>
<newAxiom>&apos;mitochondrial ncRNA surveillance&apos; SubClassOf &apos;ncRNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035946</classIRI>
<classLabel>mitochondrial mRNA surveillance</classLabel>
<newAxiom>&apos;mitochondrial mRNA surveillance&apos; SubClassOf &apos;mitochondrial mRNA catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033217</classIRI>
<classLabel>regulation of transcription from RNA polymerase II promoter in response to iron ion starvation</classLabel>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of transcription from RNA polymerase II promoter in response to iron ion starvation&apos; SubClassOf &apos;cellular response to iron ion starvation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141089</classIRI>
<classLabel>glucose sensor activity</classLabel>
<deletedAxiom>&apos;glucose sensor activity&apos; SubClassOf &apos;glucose binding&apos;</deletedAxiom>
<newAxiom>&apos;glucose sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035615</classIRI>
<classLabel>clathrin adaptor activity</classLabel>
<deletedAxiom>&apos;clathrin adaptor activity&apos; SubClassOf &apos;clathrin binding&apos;</deletedAxiom>
<newAxiom>&apos;clathrin adaptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;clathrin binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035658</classIRI>
<classLabel>Mon1-Ccz1 complex</classLabel>
<deletedAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;Mon1-Ccz1 complex&apos; SubClassOf &apos;guanyl-nucleotide exchange factor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045016</classIRI>
<classLabel>mitochondrial magnesium ion transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial magnesium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045037</classIRI>
<classLabel>protein import into chloroplast stroma</classLabel>
<deletedAxiom>&apos;protein import into chloroplast stroma&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into chloroplast stroma&apos; SubClassOf &apos;protein targeting to chloroplast&apos;</deletedAxiom>
<newAxiom>&apos;protein import into chloroplast stroma&apos; SubClassOf &apos;establishment of protein localization to chloroplast&apos;</newAxiom>
<newAxiom>&apos;protein import into chloroplast stroma&apos; SubClassOf &apos;protein transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045038</classIRI>
<classLabel>protein import into chloroplast thylakoid membrane</classLabel>
<deletedAxiom>&apos;protein import into chloroplast thylakoid membrane&apos; SubClassOf &apos;protein targeting to chloroplast&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into chloroplast thylakoid membrane&apos; SubClassOf &apos;protein targeting to membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into chloroplast thylakoid membrane&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;protein import into chloroplast thylakoid membrane&apos; SubClassOf &apos;establishment of protein localization to membrane&apos;</newAxiom>
<newAxiom>&apos;protein import into chloroplast thylakoid membrane&apos; SubClassOf &apos;establishment of protein localization to chloroplast&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045039</classIRI>
<classLabel>protein insertion into mitochondrial inner membrane</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial inner membrane&apos; SubClassOf &apos;protein insertion into mitochondrial membrane&apos;</deletedAxiom>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane&apos; SubClassOf &apos;intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane&apos; SubClassOf &apos;establishment of protein localization to mitochondrial membrane&apos;</newAxiom>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045022</classIRI>
<classLabel>early endosome to late endosome transport</classLabel>
<deletedAxiom>&apos;early endosome to late endosome transport&apos; SubClassOf &apos;cytosolic transport&apos;</deletedAxiom>
<newAxiom>&apos;early endosome to late endosome transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045046</classIRI>
<classLabel>protein import into peroxisome membrane</classLabel>
<deletedAxiom>&apos;protein import into peroxisome membrane&apos; SubClassOf &apos;protein targeting to peroxisome&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into peroxisome membrane&apos; SubClassOf &apos;protein targeting to membrane&apos;</deletedAxiom>
<newAxiom>&apos;protein import into peroxisome membrane&apos; SubClassOf &apos;establishment of protein localization to peroxisome&apos;</newAxiom>
<newAxiom>&apos;protein import into peroxisome membrane&apos; SubClassOf &apos;intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;protein import into peroxisome membrane&apos; SubClassOf &apos;establishment of protein localization to membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045040</classIRI>
<classLabel>protein insertion into mitochondrial outer membrane</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;protein insertion into mitochondrial membrane&apos;</deletedAxiom>
<newAxiom>&apos;protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;establishment of protein localization to mitochondrial membrane&apos;</newAxiom>
<newAxiom>&apos;protein insertion into mitochondrial outer membrane&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045041</classIRI>
<classLabel>protein import into mitochondrial intermembrane space</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070027</classIRI>
<classLabel>carbon monoxide sensor activity</classLabel>
<deletedAxiom>&apos;carbon monoxide sensor activity&apos; SubClassOf &apos;carbon monoxide binding&apos;</deletedAxiom>
<newAxiom>&apos;carbon monoxide sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;carbon monoxide binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106399</classIRI>
<classLabel>acyl-coenzyme A diphosphatase activity</classLabel>
<deletedAxiom>&apos;acyl-coenzyme A diphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060497</classIRI>
<classLabel>mesenchymal-endodermal cell signaling</classLabel>
<deletedAxiom>&apos;mesenchymal-endodermal cell signaling&apos; SubClassOf &apos;mesenchymal-epithelial cell signaling&apos;</deletedAxiom>
<newAxiom>&apos;mesenchymal-endodermal cell signaling&apos; SubClassOf &apos;cell-cell signaling&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072344</classIRI>
<classLabel>rescue of stalled ribosome</classLabel>
<newAxiom>&apos;rescue of stalled ribosome&apos; SubClassOf &apos;ribosome disassembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106219</classIRI>
<classLabel>zinc ion sensor activity</classLabel>
<deletedAxiom>&apos;zinc ion sensor activity&apos; SubClassOf &apos;zinc ion binding&apos;</deletedAxiom>
<newAxiom>&apos;zinc ion sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;zinc ion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035318</classIRI>
<classLabel>imaginal disc-derived wing hair outgrowth</classLabel>
<deletedAxiom>&apos;imaginal disc-derived wing hair outgrowth&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035319</classIRI>
<classLabel>imaginal disc-derived wing hair elongation</classLabel>
<deletedAxiom>&apos;imaginal disc-derived wing hair elongation&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035317</classIRI>
<classLabel>imaginal disc-derived wing hair organization</classLabel>
<deletedAxiom>&apos;imaginal disc-derived wing hair organization&apos; SubClassOf &apos;cell proliferation involved in imaginal disc-derived wing morphogenesis&apos;</deletedAxiom>
<newAxiom>&apos;imaginal disc-derived wing hair organization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;imaginal disc-derived wing morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098927</classIRI>
<classLabel>vesicle-mediated transport between endosomal compartments</classLabel>
<deletedAxiom>&apos;vesicle-mediated transport between endosomal compartments&apos; SubClassOf &apos;vesicle-mediated transport&apos;</deletedAxiom>
<newAxiom>&apos;vesicle-mediated transport between endosomal compartments&apos; SubClassOf &apos;endosomal transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072340</classIRI>
<classLabel>lactam catabolic process</classLabel>
<newAxiom>&apos;lactam catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</newAxiom>
<newAxiom>&apos;lactam catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001844</classIRI>
<classLabel>protein insertion into mitochondrial membrane involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;protein insertion into mitochondrial membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; EquivalentTo &apos;protein insertion into mitochondrial membrane&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apoptotic signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitochondrial outer membrane permeabilization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905067</classIRI>
<classLabel>negative regulation of canonical Wnt signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in heart development&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;negative regulation of Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905068</classIRI>
<classLabel>positive regulation of canonical Wnt signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in heart development&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;positive regulation of developmental process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;positive regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905066</classIRI>
<classLabel>regulation of canonical Wnt signaling pathway involved in heart development</classLabel>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in heart development&apos; SubClassOf &apos;regulation of Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in heart development&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in heart development&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098664</classIRI>
<classLabel>G protein-coupled serotonin receptor signaling pathway</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf &apos;serotonin receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098666</classIRI>
<classLabel>G protein-coupled serotonin receptor complex</classLabel>
<deletedAxiom>&apos;G protein-coupled serotonin receptor complex&apos; SubClassOf &apos;serotonin receptor complex&apos;</deletedAxiom>
<newAxiom>&apos;G protein-coupled serotonin receptor complex&apos; SubClassOf &apos;receptor complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060071</classIRI>
<classLabel>Wnt signaling pathway, planar cell polarity pathway</classLabel>
<deletedAxiom>&apos;Wnt signaling pathway, planar cell polarity pathway&apos; SubClassOf &apos;regulation of establishment of planar polarity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098506</classIRI>
<classLabel>polynucleotide 3&apos; dephosphorylation</classLabel>
<newAxiom>&apos;polynucleotide 3&apos; dephosphorylation&apos; SubClassOf &apos;nucleobase-containing compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;polynucleotide 3&apos; dephosphorylation&apos; SubClassOf &apos;macromolecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098507</classIRI>
<classLabel>polynucleotide 5&apos; dephosphorylation</classLabel>
<newAxiom>&apos;polynucleotide 5&apos; dephosphorylation&apos; SubClassOf &apos;macromolecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;polynucleotide 5&apos; dephosphorylation&apos; SubClassOf &apos;nucleobase-containing compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905239</classIRI>
<classLabel>regulation of canonical Wnt signaling pathway involved in osteoblast differentiation</classLabel>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905240</classIRI>
<classLabel>negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905241</classIRI>
<classLabel>positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;positive regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905424</classIRI>
<classLabel>regulation of Wnt-mediated midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;regulation of Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;regulation of midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905425</classIRI>
<classLabel>negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;negative regulation of Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905426</classIRI>
<classLabel>positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;positive regulation of midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;positive regulation of Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905438</classIRI>
<classLabel>non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;non-canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;non-canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052781</classIRI>
<classLabel>chitobiose catabolic process</classLabel>
<newAxiom>&apos;chitobiose catabolic process&apos; SubClassOf &apos;chitobiose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990417</classIRI>
<classLabel>snoRNA release from pre-rRNA</classLabel>
<newAxiom>&apos;snoRNA release from pre-rRNA&apos; SubClassOf &apos;sno(s)RNA metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990441</classIRI>
<classLabel>negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress</classLabel>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress&apos; SubClassOf &apos;negative regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress&apos; SubClassOf &apos;response to endoplasmic reticulum stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990440</classIRI>
<classLabel>positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress</classLabel>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress&apos; SubClassOf &apos;positive regulation of transcription from RNA polymerase II promoter in response to stress&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress&apos; SubClassOf &apos;response to endoplasmic reticulum stress&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990491</classIRI>
<classLabel>methane biosynthetic process from methanol and hydrogen</classLabel>
<deletedAxiom>&apos;methane biosynthetic process from methanol and hydrogen&apos; SubClassOf &apos;methanol metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052704</classIRI>
<classLabel>ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide</classLabel>
<newAxiom>&apos;ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide&apos; SubClassOf &apos;aromatic amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide&apos; SubClassOf &apos;imidazole-containing compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062032</classIRI>
<classLabel>cichorine biosynthetic process</classLabel>
<newAxiom>&apos;cichorine biosynthetic process&apos; SubClassOf &apos;phenol-containing compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;cichorine biosynthetic process&apos; SubClassOf &apos;heterocycle biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;cichorine biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003700</classIRI>
<classLabel>DNA-binding transcription factor activity</classLabel>
<newAxiom>&apos;DNA-binding transcription factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of DNA-templated transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990554</classIRI>
<classLabel>mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990553</classIRI>
<classLabel>mitochondrial 5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial 5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990551</classIRI>
<classLabel>mitochondrial 2-oxoadipate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial 2-oxoadipate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990550</classIRI>
<classLabel>mitochondrial alpha-ketoglutarate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial alpha-ketoglutarate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990549</classIRI>
<classLabel>mitochondrial NAD transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial NAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990548</classIRI>
<classLabel>mitochondrial FAD transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial FAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990547</classIRI>
<classLabel>mitochondrial phosphate ion transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial phosphate ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990546</classIRI>
<classLabel>mitochondrial tricarboxylic acid transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial tricarboxylic acid transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990545</classIRI>
<classLabel>mitochondrial thiamine pyrophosphate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990544</classIRI>
<classLabel>mitochondrial ATP transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial ATP transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990543</classIRI>
<classLabel>mitochondrial S-adenosyl-L-methionine transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990542</classIRI>
<classLabel>mitochondrial transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990540</classIRI>
<classLabel>mitochondrial manganese ion transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial manganese ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990575</classIRI>
<classLabel>mitochondrial L-ornithine transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial L-ornithine transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990559</classIRI>
<classLabel>mitochondrial coenzyme A transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial coenzyme A transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990558</classIRI>
<classLabel>mitochondrial malonate(1-) transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial malonate(1-) transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990557</classIRI>
<classLabel>mitochondrial sulfate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990556</classIRI>
<classLabel>mitochondrial isopropylmalate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial isopropylmalate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990555</classIRI>
<classLabel>mitochondrial oxaloacetate transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial oxaloacetate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990504</classIRI>
<classLabel>dense core granule exocytosis</classLabel>
<newAxiom>&apos;dense core granule exocytosis&apos; SubClassOf &apos;dense core granule localization&apos;</newAxiom>
<newAxiom>&apos;dense core granule exocytosis&apos; SubClassOf &apos;establishment of vesicle localization&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052602</classIRI>
<classLabel>4-chloronitrobenzene nitroreductase activity</classLabel>
<deletedAxiom>&apos;4-chloronitrobenzene nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052603</classIRI>
<classLabel>1-chloro-4-nitrosobenzene nitroreductase activity</classLabel>
<deletedAxiom>&apos;1-chloro-4-nitrosobenzene nitroreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990624</classIRI>
<classLabel>guanyl nucleotide exchange factor inhibitor activity</classLabel>
<deletedAxiom>&apos;guanyl nucleotide exchange factor inhibitor activity&apos; SubClassOf &apos;enzyme regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;guanyl nucleotide exchange factor inhibitor activity&apos; SubClassOf &apos;enzyme inhibitor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042945</classIRI>
<classLabel>D-serine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;D-serine transmembrane transporter activity&apos; SubClassOf &apos;serine transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001159</classIRI>
<classLabel>regulation of protein localization by the Cvt pathway</classLabel>
<deletedAxiom>&apos;regulation of protein localization by the Cvt pathway&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003267</classIRI>
<classLabel>canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation&apos; EquivalentTo &apos;canonical Wnt signaling pathway involved in heart development&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of secondary heart field cardioblast proliferation&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in regulation of cell proliferation&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of secondary heart field cardioblast proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001172</classIRI>
<classLabel>positive regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;positive regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;positive regulation of glucose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001154</classIRI>
<classLabel>regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;regulation of glucose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904954</classIRI>
<classLabel>canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904955</classIRI>
<classLabel>planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;Wnt signaling pathway, planar cell polarity pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;Wnt signaling pathway, planar cell polarity pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904953</classIRI>
<classLabel>Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation</classLabel>
<deletedAxiom>&apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf &apos;Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; EquivalentTo &apos;Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;midbrain dopaminergic neuron differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;midbrain dopaminergic neuron differentiation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001155</classIRI>
<classLabel>negative regulation of glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;negative regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003136</classIRI>
<classLabel>negative regulation of heart induction by canonical Wnt signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;regulation of heart induction by canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in heart development&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;negative regulation of heart induction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of heart induction by canonical Wnt signaling pathway&apos; SubClassOf &apos;negative regulation of cardioblast cell fate specification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015194</classIRI>
<classLabel>L-serine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-serine transmembrane transporter activity&apos; SubClassOf &apos;serine transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030655</classIRI>
<classLabel>beta-lactam antibiotic catabolic process</classLabel>
<deletedAxiom>&apos;beta-lactam antibiotic catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;beta-lactam antibiotic catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902626</classIRI>
<classLabel>assembly of large subunit precursor of preribosome</classLabel>
<newAxiom>&apos;assembly of large subunit precursor of preribosome&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ribosomal large subunit assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032935</classIRI>
<classLabel>sterol sensor activity</classLabel>
<deletedAxiom>&apos;sterol sensor activity&apos; SubClassOf &apos;sterol binding&apos;</deletedAxiom>
<newAxiom>&apos;sterol sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sterol binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900151</classIRI>
<classLabel>regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay</classLabel>
<deletedAxiom>&apos;regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay&apos; SubClassOf &apos;regulation of translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900152</classIRI>
<classLabel>negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay</classLabel>
<deletedAxiom>&apos;negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay&apos; SubClassOf &apos;positive regulation of translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032979</classIRI>
<classLabel>protein insertion into mitochondrial inner membrane from matrix</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;intracellular protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;establishment of protein localization to mitochondrial membrane&apos;</deletedAxiom>
<newAxiom>&apos;protein insertion into mitochondrial inner membrane from matrix&apos; SubClassOf &apos;protein insertion into mitochondrial membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032990</classIRI>
<classLabel>cell part morphogenesis</classLabel>
<deletedAxiom>&apos;cell part morphogenesis&apos; SubClassOf &apos;cellular component morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902955</classIRI>
<classLabel>positive regulation of early endosome to recycling endosome transport</classLabel>
<deletedAxiom>&apos;positive regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;positive regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902954</classIRI>
<classLabel>regulation of early endosome to recycling endosome transport</classLabel>
<deletedAxiom>&apos;regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of early endosome to recycling endosome transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019826</classIRI>
<classLabel>oxygen sensor activity</classLabel>
<deletedAxiom>&apos;oxygen sensor activity&apos; SubClassOf &apos;oxygen binding&apos;</deletedAxiom>
<newAxiom>&apos;oxygen sensor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxygen binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150038</classIRI>
<classLabel>postsynaptic dense core vesicle exocytosis</classLabel>
<deletedAxiom>&apos;postsynaptic dense core vesicle exocytosis&apos; SubClassOf &apos;establishment of localization in cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900483</classIRI>
<classLabel>regulation of protein targeting to vacuolar membrane</classLabel>
<deletedAxiom>&apos;regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900484</classIRI>
<classLabel>negative regulation of protein targeting to vacuolar membrane</classLabel>
<deletedAxiom>&apos;negative regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900485</classIRI>
<classLabel>positive regulation of protein targeting to vacuolar membrane</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900477</classIRI>
<classLabel>negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter&apos; EquivalentTo &apos;negative regulation of transcription by RNA polymerase II&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;G1/S transition of mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of G1/S transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter&apos; SubClassOf &apos;negative regulation of transcription by RNA polymerase II&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030150</classIRI>
<classLabel>protein import into mitochondrial matrix</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140466</classIRI>
<classLabel>iron-sulfur cluster export from the mitochondrion</classLabel>
<newAxiom>&apos;iron-sulfur cluster export from the mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019650</classIRI>
<classLabel>glycolytic fermentation to butanediol</classLabel>
<newAxiom>&apos;glycolytic fermentation to butanediol&apos; SubClassOf &apos;glucose metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic fermentation to butanediol&apos; SubClassOf &apos;butanediol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019655</classIRI>
<classLabel>glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;glycolytic fermentation to ethanol&apos; SubClassOf &apos;glucose metabolic process&apos;</newAxiom>
<newAxiom>&apos;glycolytic fermentation to ethanol&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019658</classIRI>
<classLabel>glucose fermentation to lactate and acetate</classLabel>
<deletedAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;glucose catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glucose fermentation to lactate and acetate&apos; SubClassOf &apos;glucose catabolic process to lactate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019664</classIRI>
<classLabel>mixed acid fermentation</classLabel>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;lactate metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;2-oxoglutarate metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;succinate metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;ethanol metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;formate metabolic process&apos;</newAxiom>
<newAxiom>&apos;mixed acid fermentation&apos; SubClassOf &apos;glucose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019667</classIRI>
<classLabel>anaerobic L-alanine catabolic process</classLabel>
<newAxiom>&apos;anaerobic L-alanine catabolic process&apos; SubClassOf &apos;L-alanine catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019669</classIRI>
<classLabel>anaerobic glycine catabolic process</classLabel>
<newAxiom>&apos;anaerobic glycine catabolic process&apos; SubClassOf &apos;glycine catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019670</classIRI>
<classLabel>anaerobic glutamate catabolic process</classLabel>
<newAxiom>&apos;anaerobic glutamate catabolic process&apos; SubClassOf &apos;glutamate catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030030</classIRI>
<classLabel>cell projection organization</classLabel>
<deletedAxiom>&apos;cell projection organization&apos; SubClassOf &apos;cell population proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019549</classIRI>
<classLabel>glutamate catabolic process to succinate via succinate semialdehyde</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to succinate via succinate semialdehyde&apos; SubClassOf &apos;succinate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900739</classIRI>
<classLabel>regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of establishment of protein localization to mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of mitochondrion organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of protein localization to membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900740</classIRI>
<classLabel>positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of establishment of protein localization to mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of protein localization to membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900789</classIRI>
<classLabel>pseurotin A catabolic process</classLabel>
<deletedAxiom>&apos;pseurotin A catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pseurotin A catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019462</classIRI>
<classLabel>glutamine catabolic process to fumarate, using glutaminase</classLabel>
<deletedAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;glutamate catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutamine catabolic process to fumarate, using glutaminase&apos; SubClassOf &apos;glutamine catabolic process to fumarate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019384</classIRI>
<classLabel>caprolactam catabolic process</classLabel>
<deletedAxiom>&apos;caprolactam catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;caprolactam catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019385</classIRI>
<classLabel>methanogenesis, from acetate</classLabel>
<newAxiom>&apos;methanogenesis, from acetate&apos; SubClassOf &apos;acetate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019387</classIRI>
<classLabel>methanogenesis, from methanol</classLabel>
<newAxiom>&apos;methanogenesis, from methanol&apos; SubClassOf &apos;methanol metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044339</classIRI>
<classLabel>canonical Wnt signaling pathway involved in osteoblast differentiation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;osteoblast differentiation&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;osteoblast differentiation&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in osteoblast differentiation&apos; SubClassOf &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140141</classIRI>
<classLabel>mitochondrial potassium ion transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial potassium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140140</classIRI>
<classLabel>mitochondrial guanine nucleotide transmembrane transport</classLabel>
<newAxiom>&apos;mitochondrial guanine nucleotide transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140110</classIRI>
<classLabel>transcription regulator activity</classLabel>
<deletedAxiom>&apos;transcription regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of DNA-templated transcription&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160118</classIRI>
<classLabel>tRNA (guanine(7)-N2)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(7)-N2)-methyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(7)-N2)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160117</classIRI>
<classLabel>tRNA (guanine(6)-N2)-methyltransferase activity</classLabel>
<newAxiom>'tRNA (guanine(6)-N2)-methyltransferase activity' SubClassOf 'tRNA (guanine) methyltransferase activity'</newAxiom>
<newAxiom>'tRNA (guanine(6)-N2)-methyltransferase activity' SubClassOf 'N-methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160119</classIRI>
<classLabel>cuproptosis</classLabel>
<newAxiom>'cuproptosis' SubClassOf 'programmed cell death'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160121</classIRI>
<classLabel>bis(monoacylglycero)phosphate synthase activity</classLabel>
<newAxiom>'bis(monoacylglycero)phosphate synthase activity' SubClassOf 'acyltransferase activity, transferring groups other than amino-acyl groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160120</classIRI>
<classLabel>branched-chain alpha-keto acid dehydrogenase complex</classLabel>
<newAxiom>'branched-chain alpha-keto acid dehydrogenase complex' SubClassOf 'mitochondrial protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160124</classIRI>
<classLabel>guanyl nucleotide exchange factor activator activity</classLabel>
<newAxiom>'guanyl nucleotide exchange factor activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160123</classIRI>
<classLabel>structural constituent of nuclear lamina</classLabel>
<newAxiom>'structural constituent of nuclear lamina' SubClassOf 'structural molecule activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160122</classIRI>
<classLabel>corneal epithelial cell differentiation</classLabel>
<newAxiom>'corneal epithelial cell differentiation' SubClassOf 'epithelial cell differentiation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180024</classIRI>
<classLabel>membrane grommet activity</classLabel>
<newAxiom>'membrane grommet activity' SubClassOf 'molecular_function'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180023</classIRI>
<classLabel>cytosolic large ribosomal subunit assembly</classLabel>
<newAxiom>'cytosolic large ribosomal subunit assembly' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosolic ribosome assembly'</newAxiom>
<newAxiom>'cytosolic large ribosomal subunit assembly' SubClassOf 'ribosomal large subunit assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180022</classIRI>
<classLabel>RQC-trigger complex</classLabel>
<newAxiom>'RQC-trigger complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180026</classIRI>
<classLabel>mitochondrial small ribosomal subunit assembly</classLabel>
<newAxiom>'mitochondrial small ribosomal subunit assembly' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'mitochondrial ribosome assembly'</newAxiom>
<newAxiom>'mitochondrial small ribosomal subunit assembly' SubClassOf 'ribosomal small subunit assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180025</classIRI>
<classLabel>cytosolic small ribosomal subunit assembly</classLabel>
<newAxiom>'cytosolic small ribosomal subunit assembly' SubClassOf 'ribosomal small subunit assembly'</newAxiom>
<newAxiom>'cytosolic small ribosomal subunit assembly' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosolic ribosome assembly'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141106</classIRI>
<classLabel>tRNA methyltransferase activator activity</classLabel>
<newAxiom>'tRNA methyltransferase activator activity' SubClassOf 'methyltransferase regulator activity'</newAxiom>
<newAxiom>'tRNA methyltransferase activator activity' SubClassOf 'enzyme activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141109</classIRI>
<classLabel>transporter activator activity</classLabel>
<newAxiom>'transporter activator activity' SubClassOf 'transporter regulator activity'</newAxiom>
<newAxiom>'transporter activator activity' SubClassOf 'molecular function activator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141108</classIRI>
<classLabel>transporter regulator activity</classLabel>
<newAxiom>'transporter regulator activity' SubClassOf 'molecular function regulator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141107</classIRI>
<classLabel>methyltransferase regulator activity</classLabel>
<newAxiom>'methyltransferase regulator activity' SubClassOf 'enzyme regulator activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141113</classIRI>
<classLabel>negative regulation of Wnt signaling pathway, planar cell polarity pathway</classLabel>
<newAxiom>'negative regulation of Wnt signaling pathway, planar cell polarity pathway' SubClassOf 'regulation of Wnt signaling pathway, planar cell polarity pathway'</newAxiom>
<newAxiom>'negative regulation of Wnt signaling pathway, planar cell polarity pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'Wnt signaling pathway, planar cell polarity pathway')</newAxiom>
<newAxiom>'negative regulation of Wnt signaling pathway, planar cell polarity pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'Wnt signaling pathway, planar cell polarity pathway'</newAxiom>
<newAxiom>'negative regulation of Wnt signaling pathway, planar cell polarity pathway' SubClassOf 'negative regulation of non-canonical Wnt signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141112</classIRI>
<classLabel>broken chromosome clustering</classLabel>
<newAxiom>'broken chromosome clustering' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'DNA damage response'</newAxiom>
<newAxiom>'broken chromosome clustering' SubClassOf 'chromosome organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141111</classIRI>
<classLabel>positive regulation of cGAS/STING signaling pathway</classLabel>
<newAxiom>'positive regulation of cGAS/STING signaling pathway' SubClassOf 'regulation of cytoplasmic pattern recognition receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of cGAS/STING signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some 'cGAS/STING signaling pathway'</newAxiom>
<newAxiom>'positive regulation of cGAS/STING signaling pathway' SubClassOf 'positive regulation of pattern recognition receptor signaling pathway'</newAxiom>
<newAxiom>'positive regulation of cGAS/STING signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002213 some 'cGAS/STING signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141110</classIRI>
<classLabel>transporter inhibitor activity</classLabel>
<newAxiom>'transporter inhibitor activity' SubClassOf 'transporter regulator activity'</newAxiom>
<newAxiom>'transporter inhibitor activity' SubClassOf 'molecular function inhibitor activity'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>