<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
1168
</numberChangedClasses>
<numberNewClasses>
71
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071847</classIRI>
<classLabel>TNFSF11-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;TNFSF11-mediated signaling pathway&apos; SubClassOf &apos;tumor necrosis factor-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071848</classIRI>
<classLabel>positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling</classLabel>
<deletedAxiom>&apos;positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling&apos; SubClassOf &apos;positive regulation of ERK1 and ERK2 cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling&apos; SubClassOf &apos;TNFSF11-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019279</classIRI>
<classLabel>L-methionine biosynthetic process from L-homoserine via cystathionine</classLabel>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via cystathionine&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019288</classIRI>
<classLabel>isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway</classLabel>
<deletedAxiom>&apos;isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; SubClassOf &apos;pyruvate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019283</classIRI>
<classLabel>L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine</classLabel>
<newAxiom>&apos;L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071872</classIRI>
<classLabel>cellular response to epinephrine stimulus</classLabel>
<deletedAxiom>&apos;cellular response to epinephrine stimulus&apos; SubClassOf &apos;cellular response to catecholamine stimulus&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to epinephrine stimulus&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071871</classIRI>
<classLabel>response to epinephrine</classLabel>
<deletedAxiom>&apos;response to epinephrine&apos; SubClassOf &apos;response to catecholamine&apos;</deletedAxiom>
<newAxiom>&apos;response to epinephrine&apos; SubClassOf &apos;response to chemical&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071894</classIRI>
<classLabel>histone H2B conserved C-terminal lysine ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2B conserved C-terminal lysine ubiquitination&apos; SubClassOf &apos;histone H2B ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140062</classIRI>
<classLabel>5-formylcytosine dioxygenase activity</classLabel>
<deletedAxiom>&apos;5-formylcytosine dioxygenase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140061</classIRI>
<classLabel>5-hydroxymethylcytosine dioxygenase activity</classLabel>
<deletedAxiom>&apos;5-hydroxymethylcytosine dioxygenase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140021</classIRI>
<classLabel>mitochondrial ADP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ADP transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial ADP transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009861</classIRI>
<classLabel>jasmonic acid and ethylene-dependent systemic resistance</classLabel>
<deletedAxiom>&apos;jasmonic acid and ethylene-dependent systemic resistance&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;jasmonic acid and ethylene-dependent systemic resistance&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007228</classIRI>
<classLabel>positive regulation of hh target transcription factor activity</classLabel>
<deletedAxiom>&apos;positive regulation of hh target transcription factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;signal transduction downstream of smoothened&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of hh target transcription factor activity&apos; SubClassOf &apos;positive regulation of DNA-binding transcription factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007227</classIRI>
<classLabel>signal transduction downstream of smoothened</classLabel>
<deletedAxiom>&apos;signal transduction downstream of smoothened&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;signal transduction downstream of smoothened&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;smoothened signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046804</classIRI>
<classLabel>peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide</classLabel>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide&apos; SubClassOf &apos;peptidyl-threonine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007249</classIRI>
<classLabel>canonical NF-kappaB signal transduction</classLabel>
<deletedAxiom>&apos;canonical NF-kappaB signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;canonical NF-kappaB signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007254</classIRI>
<classLabel>JNK cascade</classLabel>
<deletedAxiom>&apos;JNK cascade&apos; SubClassOf &apos;stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;JNK cascade&apos; SubClassOf &apos;MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019240</classIRI>
<classLabel>citrulline biosynthetic process</classLabel>
<newAxiom>&apos;citrulline biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019241</classIRI>
<classLabel>citrulline catabolic process</classLabel>
<newAxiom>&apos;citrulline catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032217</classIRI>
<classLabel>riboflavin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;riboflavin transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007264</classIRI>
<classLabel>small GTPase mediated signal transduction</classLabel>
<deletedAxiom>&apos;small GTPase mediated signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;small GTPase mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007263</classIRI>
<classLabel>nitric oxide mediated signal transduction</classLabel>
<deletedAxiom>&apos;nitric oxide mediated signal transduction&apos; SubClassOf &apos;second-messenger-mediated signaling&apos;</deletedAxiom>
<newAxiom>&apos;nitric oxide mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007266</classIRI>
<classLabel>Rho protein signal transduction</classLabel>
<deletedAxiom>&apos;Rho protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Rho protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046848</classIRI>
<classLabel>hydroxyapatite binding</classLabel>
<deletedAxiom>&apos;hydroxyapatite binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;hydroxyapatite binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071712</classIRI>
<classLabel>ER-associated misfolded protein catabolic process</classLabel>
<deletedAxiom>&apos;ER-associated misfolded protein catabolic process&apos; SubClassOf &apos;protein quality control for misfolded or incompletely synthesized proteins&apos;</deletedAxiom>
<deletedAxiom>&apos;ER-associated misfolded protein catabolic process&apos; SubClassOf &apos;ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;ER-associated misfolded protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to misfolded protein&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034772</classIRI>
<classLabel>histone H4-K20 dimethylation</classLabel>
<deletedAxiom>&apos;histone H4-K20 dimethylation&apos; SubClassOf &apos;peptidyl-lysine dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H4-K20 dimethylation&apos; SubClassOf &apos;histone H4-K20 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034770</classIRI>
<classLabel>histone H4-K20 methylation</classLabel>
<deletedAxiom>&apos;histone H4-K20 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034775</classIRI>
<classLabel>glutathione transmembrane transport</classLabel>
<deletedAxiom>&apos;glutathione transmembrane transport&apos; SubClassOf &apos;transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glutathione transmembrane transport&apos; SubClassOf &apos;tripeptide transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034773</classIRI>
<classLabel>histone H4-K20 trimethylation</classLabel>
<deletedAxiom>&apos;histone H4-K20 trimethylation&apos; SubClassOf &apos;histone H4-K20 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H4-K20 trimethylation&apos; SubClassOf &apos;peptidyl-lysine trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046783</classIRI>
<classLabel>modification by virus of host polysomes</classLabel>
<deletedAxiom>&apos;modification by virus of host polysomes&apos; SubClassOf &apos;modulation by virus of host translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046778</classIRI>
<classLabel>modification by virus of host mRNA processing</classLabel>
<deletedAxiom>&apos;modification by virus of host mRNA processing&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046773</classIRI>
<classLabel>suppression by virus of host translation termination</classLabel>
<deletedAxiom>&apos;suppression by virus of host translation termination&apos; SubClassOf &apos;modulation by virus of host translation&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host translation termination&apos; SubClassOf &apos;suppression by virus of host translation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046776</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;antigen processing and presentation of peptide antigen via MHC class I&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;antigen processing and presentation of peptide antigen via MHC class I&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046792</classIRI>
<classLabel>suppression by virus of host cell cycle arrest</classLabel>
<deletedAxiom>&apos;suppression by virus of host cell cycle arrest&apos; SubClassOf &apos;perturbation by virus of host cell cycle regulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046790</classIRI>
<classLabel>virion binding</classLabel>
<deletedAxiom>&apos;virion binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;virion binding&apos; SubClassOf &apos;protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044154</classIRI>
<classLabel>histone H3-K14 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K14 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034720</classIRI>
<classLabel>histone H3-K4 demethylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 demethylation&apos; SubClassOf &apos;histone lysine demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034721</classIRI>
<classLabel>histone H3-K4 demethylation, trimethyl-H3-K4-specific</classLabel>
<deletedAxiom>&apos;histone H3-K4 demethylation, trimethyl-H3-K4-specific&apos; SubClassOf &apos;histone H3-K4 demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034729</classIRI>
<classLabel>histone H3-K79 methylation</classLabel>
<deletedAxiom>&apos;histone H3-K79 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020013</classIRI>
<classLabel>modulation by symbiont of host erythrocyte aggregation</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host erythrocyte aggregation&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;erythrocyte aggregation&apos;)</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host erythrocyte aggregation&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;erythrocyte aggregation&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044000</classIRI>
<classLabel>movement in host</classLabel>
<deletedAxiom>&apos;movement in host&apos; SubClassOf &apos;biological process involved in interaction with host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044001</classIRI>
<classLabel>migration in host</classLabel>
<deletedAxiom>&apos;migration in host&apos; SubClassOf &apos;movement in host&apos;</deletedAxiom>
<newAxiom>&apos;migration in host&apos; SubClassOf &apos;biological process involved in interaction with host&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032017</classIRI>
<classLabel>positive regulation of Ran protein signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of Ran protein signal transduction&apos; SubClassOf &apos;positive regulation of Ras protein signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Ran protein signal transduction&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;Ran protein signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Ran protein signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;Ran protein signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Ran protein signal transduction&apos; SubClassOf &apos;regulation of Ran protein signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032016</classIRI>
<classLabel>negative regulation of Ran protein signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of Ran protein signal transduction&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;Ran protein signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Ran protein signal transduction&apos; SubClassOf &apos;regulation of Ran protein signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Ran protein signal transduction&apos; SubClassOf &apos;negative regulation of Ras protein signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of Ran protein signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;Ran protein signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019054</classIRI>
<classLabel>modulation by virus of host cellular process</classLabel>
<deletedAxiom>&apos;modulation by virus of host cellular process&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host cellular process&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019055</classIRI>
<classLabel>perturbation by virus of host cell cycle regulation</classLabel>
<deletedAxiom>&apos;perturbation by virus of host cell cycle regulation&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host cell cycle regulation&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;perturbation by virus of host cell cycle regulation&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019056</classIRI>
<classLabel>modulation by virus of host transcription</classLabel>
<deletedAxiom>&apos;modulation by virus of host transcription&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host transcription&apos; SubClassOf &apos;modulation by symbiont of host transcription&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019057</classIRI>
<classLabel>modulation by virus of host translation</classLabel>
<deletedAxiom>&apos;modulation by virus of host translation&apos; SubClassOf &apos;modulation by symbiont of host translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032011</classIRI>
<classLabel>ARF protein signal transduction</classLabel>
<deletedAxiom>&apos;ARF protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;ARF protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032013</classIRI>
<classLabel>negative regulation of ARF protein signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of ARF protein signal transduction&apos; SubClassOf &apos;negative regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ARF protein signal transduction&apos; SubClassOf &apos;negative regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032012</classIRI>
<classLabel>regulation of ARF protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of ARF protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ARF protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032015</classIRI>
<classLabel>regulation of Ran protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Ran protein signal transduction&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;Ran protein signal transduction&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of Ran protein signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;Ran protein signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Ran protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032014</classIRI>
<classLabel>positive regulation of ARF protein signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of ARF protein signal transduction&apos; SubClassOf &apos;positive regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ARF protein signal transduction&apos; SubClassOf &apos;positive regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019050</classIRI>
<classLabel>suppression by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host process&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host apoptotic process&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019051</classIRI>
<classLabel>induction by virus of host apoptotic process</classLabel>
<deletedAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
<newAxiom>&apos;induction by virus of host apoptotic process&apos; SubClassOf &apos;modulation by virus of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046687</classIRI>
<classLabel>response to chromate</classLabel>
<deletedAxiom>&apos;response to chromate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046679</classIRI>
<classLabel>response to streptomycin</classLabel>
<deletedAxiom>&apos;response to streptomycin&apos; SubClassOf &apos;response to nitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to streptomycin&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044032</classIRI>
<classLabel>modulation by symbiont of indole acetic acid levels in host</classLabel>
<deletedAxiom>&apos;modulation by symbiont of indole acetic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019090</classIRI>
<classLabel>mitochondrial rRNA export from mitochondrion</classLabel>
<deletedAxiom>&apos;mitochondrial rRNA export from mitochondrion&apos; SubClassOf &apos;transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial rRNA export from mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial rRNA export from mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170037</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044029</classIRI>
<classLabel>positive regulation of gene expression via CpG island demethylation</classLabel>
<deletedAxiom>&apos;positive regulation of gene expression via CpG island demethylation&apos; SubClassOf &apos;transcription initiation-coupled chromatin remodeling&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of gene expression via CpG island demethylation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141137</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044083</classIRI>
<classLabel>perturbation of host Rho protein signal transduction</classLabel>
<deletedAxiom>&apos;perturbation of host Rho protein signal transduction&apos; SubClassOf &apos;regulation of Rho protein signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044079</classIRI>
<classLabel>modulation by symbiont of host neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host neurotransmitter secretion&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;neurotransmitter secretion&apos;)</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host neurotransmitter secretion&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;neurotransmitter secretion&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044071</classIRI>
<classLabel>perturbation of host cell cycle progression</classLabel>
<deletedAxiom>&apos;perturbation of host cell cycle progression&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;)</deletedAxiom>
<deletedAxiom>&apos;perturbation of host cell cycle progression&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044072</classIRI>
<classLabel>suppression of host cell cycle progression</classLabel>
<deletedAxiom>&apos;suppression of host cell cycle progression&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of host cell cycle progression&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell cycle process&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression of host cell cycle progression&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044073</classIRI>
<classLabel>modulation by symbiont of host translation</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host translation&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host translation&apos; SubClassOf &apos;regulation of translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044074</classIRI>
<classLabel>negative regulation by symbiont of host translation</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host translation&apos; SubClassOf &apos;negative regulation of translation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host translation&apos; SubClassOf &apos;modulation by symbiont of host translation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009627</classIRI>
<classLabel>systemic acquired resistance</classLabel>
<deletedAxiom>&apos;systemic acquired resistance&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;systemic acquired resistance&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034634</classIRI>
<classLabel>glutathione transmembrane transporter activity</classLabel>
<newAxiom>&apos;glutathione transmembrane transporter activity&apos; SubClassOf &apos;tripeptide transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glutathione transmembrane transporter activity&apos; SubClassOf &apos;sulfur compound transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glutathione transmembrane transporter activity&apos; SubClassOf &apos;modified amino acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034635</classIRI>
<classLabel>glutathione transport</classLabel>
<newAxiom>&apos;glutathione transport&apos; SubClassOf &apos;tripeptide transport&apos;</newAxiom>
<newAxiom>&apos;glutathione transport&apos; SubClassOf &apos;sulfur compound transport&apos;</newAxiom>
<newAxiom>&apos;glutathione transport&apos; SubClassOf &apos;modified amino acid transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046516</classIRI>
<classLabel>hypusine metabolic process</classLabel>
<deletedAxiom>&apos;hypusine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;hypusine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;hypusine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071524</classIRI>
<classLabel>pyrrolysine biosynthetic process</classLabel>
<deletedAxiom>&apos;pyrrolysine biosynthetic process&apos; SubClassOf &apos;carboxylic acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;pyrrolysine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071525</classIRI>
<classLabel>pyrrolysine metabolic process</classLabel>
<deletedAxiom>&apos;pyrrolysine metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;pyrrolysine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046557</classIRI>
<classLabel>glucan endo-1,6-beta-glucosidase activity</classLabel>
<deletedAxiom>&apos;glucan endo-1,6-beta-glucosidase activity&apos; SubClassOf &apos;beta-glucosidase activity&apos;</deletedAxiom>
<newAxiom>&apos;glucan endo-1,6-beta-glucosidase activity&apos; SubClassOf &apos;glucosidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071506</classIRI>
<classLabel>cellular response to mycophenolic acid</classLabel>
<deletedAxiom>&apos;cellular response to mycophenolic acid&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071505</classIRI>
<classLabel>response to mycophenolic acid</classLabel>
<deletedAxiom>&apos;response to mycophenolic acid&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071557</classIRI>
<classLabel>histone H3-K27 demethylation</classLabel>
<deletedAxiom>&apos;histone H3-K27 demethylation&apos; SubClassOf &apos;histone lysine demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071572</classIRI>
<classLabel>histone H3-K56 deacetylation</classLabel>
<deletedAxiom>&apos;histone H3-K56 deacetylation&apos; SubClassOf &apos;histone H3 deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010452</classIRI>
<classLabel>histone H3-K36 methylation</classLabel>
<deletedAxiom>&apos;histone H3-K36 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046416</classIRI>
<classLabel>D-amino acid metabolic process</classLabel>
<newAxiom>&apos;D-amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046418</classIRI>
<classLabel>nopaline metabolic process</classLabel>
<deletedAxiom>&apos;nopaline metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;nopaline metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009496</classIRI>
<classLabel>plastoquinol--plastocyanin reductase activity</classLabel>
<newAxiom>&apos;plastoquinol--plastocyanin reductase activity&apos; SubClassOf &apos;electron transfer activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046440</classIRI>
<classLabel>L-lysine metabolic process</classLabel>
<newAxiom>&apos;L-lysine metabolic process&apos; SubClassOf &apos;aspartate family amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046444</classIRI>
<classLabel>FMN metabolic process</classLabel>
<deletedAxiom>&apos;FMN metabolic process&apos; SubClassOf &apos;ribitol phosphate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046437</classIRI>
<classLabel>D-amino acid biosynthetic process</classLabel>
<newAxiom>&apos;D-amino acid biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;D-amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046439</classIRI>
<classLabel>L-cysteine metabolic process</classLabel>
<deletedAxiom>&apos;L-cysteine metabolic process&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-cysteine metabolic process&apos; SubClassOf &apos;serine family amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046498</classIRI>
<classLabel>S-adenosylhomocysteine metabolic process</classLabel>
<deletedAxiom>&apos;S-adenosylhomocysteine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;S-adenosylhomocysteine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;S-adenosylhomocysteine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071414</classIRI>
<classLabel>cellular response to methotrexate</classLabel>
<deletedAxiom>&apos;cellular response to methotrexate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071462</classIRI>
<classLabel>cellular response to water stimulus</classLabel>
<deletedAxiom>&apos;cellular response to water stimulus&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071399</classIRI>
<classLabel>cellular response to linoleic acid</classLabel>
<deletedAxiom>&apos;cellular response to linoleic acid&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009415</classIRI>
<classLabel>response to water</classLabel>
<deletedAxiom>&apos;response to water&apos; SubClassOf &apos;response to organic substance&apos;</deletedAxiom>
<deletedAxiom>&apos;response to water&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010420</classIRI>
<classLabel>3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity</classLabel>
<newAxiom>&apos;3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ubiquinone biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009444</classIRI>
<classLabel>pyruvate oxidation</classLabel>
<deletedAxiom>&apos;pyruvate oxidation&apos; SubClassOf &apos;pyruvate metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009449</classIRI>
<classLabel>gamma-aminobutyric acid biosynthetic process</classLabel>
<newAxiom>&apos;gamma-aminobutyric acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009448</classIRI>
<classLabel>gamma-aminobutyric acid metabolic process</classLabel>
<deletedAxiom>&apos;gamma-aminobutyric acid metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;gamma-aminobutyric acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009450</classIRI>
<classLabel>gamma-aminobutyric acid catabolic process</classLabel>
<newAxiom>&apos;gamma-aminobutyric acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046300</classIRI>
<classLabel>2,4-dichlorophenoxyacetic acid catabolic process</classLabel>
<deletedAxiom>&apos;2,4-dichlorophenoxyacetic acid catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010348</classIRI>
<classLabel>lithium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;lithium:proton antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010363</classIRI>
<classLabel>regulation of plant-type hypersensitive response</classLabel>
<deletedAxiom>&apos;regulation of plant-type hypersensitive response&apos; SubClassOf &apos;regulation of biological process involved in symbiotic interaction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046313</classIRI>
<classLabel>phosphoarginine catabolic process</classLabel>
<deletedAxiom>&apos;phosphoarginine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;phosphoarginine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phosphoarginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;phosphoarginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046312</classIRI>
<classLabel>phosphoarginine biosynthetic process</classLabel>
<deletedAxiom>&apos;phosphoarginine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;phosphoarginine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;phosphoarginine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046343</classIRI>
<classLabel>streptomycin metabolic process</classLabel>
<deletedAxiom>&apos;streptomycin metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;streptomycin metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010390</classIRI>
<classLabel>histone monoubiquitination</classLabel>
<deletedAxiom>&apos;histone monoubiquitination&apos; SubClassOf &apos;protein monoubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;histone monoubiquitination&apos; SubClassOf &apos;histone ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046330</classIRI>
<classLabel>positive regulation of JNK cascade</classLabel>
<deletedAxiom>&apos;positive regulation of JNK cascade&apos; SubClassOf &apos;positive regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of JNK cascade&apos; SubClassOf &apos;positive regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046328</classIRI>
<classLabel>regulation of JNK cascade</classLabel>
<deletedAxiom>&apos;regulation of JNK cascade&apos; SubClassOf &apos;regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;regulation of JNK cascade&apos; SubClassOf &apos;regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046329</classIRI>
<classLabel>negative regulation of JNK cascade</classLabel>
<deletedAxiom>&apos;negative regulation of JNK cascade&apos; SubClassOf &apos;negative regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of JNK cascade&apos; SubClassOf &apos;negative regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071311</classIRI>
<classLabel>cellular response to acetate</classLabel>
<deletedAxiom>&apos;cellular response to acetate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to acetate&apos; SubClassOf &apos;cellular response to nitrogen compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071315</classIRI>
<classLabel>cellular response to morphine</classLabel>
<deletedAxiom>&apos;cellular response to morphine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071314</classIRI>
<classLabel>cellular response to cocaine</classLabel>
<deletedAxiom>&apos;cellular response to cocaine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071319</classIRI>
<classLabel>cellular response to benzoic acid</classLabel>
<deletedAxiom>&apos;cellular response to benzoic acid&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071318</classIRI>
<classLabel>cellular response to ATP</classLabel>
<deletedAxiom>&apos;cellular response to ATP&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071302</classIRI>
<classLabel>cellular response to vitamin B2</classLabel>
<deletedAxiom>&apos;cellular response to vitamin B2&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071301</classIRI>
<classLabel>cellular response to vitamin B1</classLabel>
<deletedAxiom>&apos;cellular response to vitamin B1&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071277</classIRI>
<classLabel>cellular response to calcium ion</classLabel>
<deletedAxiom>&apos;cellular response to calcium ion&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to calcium ion&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071283</classIRI>
<classLabel>cellular response to iron(III) ion</classLabel>
<deletedAxiom>&apos;cellular response to iron(III) ion&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071285</classIRI>
<classLabel>cellular response to lithium ion</classLabel>
<deletedAxiom>&apos;cellular response to lithium ion&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to lithium ion&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071268</classIRI>
<classLabel>homocysteine biosynthetic process</classLabel>
<newAxiom>&apos;homocysteine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;homocysteine biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071272</classIRI>
<classLabel>morphine metabolic process</classLabel>
<deletedAxiom>&apos;morphine metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071273</classIRI>
<classLabel>morphine catabolic process</classLabel>
<deletedAxiom>&apos;morphine catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071298</classIRI>
<classLabel>cellular response to L-ascorbic acid</classLabel>
<deletedAxiom>&apos;cellular response to L-ascorbic acid&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010323</classIRI>
<classLabel>negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway</classLabel>
<deletedAxiom>&apos;negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061809</classIRI>
<classLabel>NAD+ nucleotidase, cyclic ADP-ribose generating</classLabel>
<deletedAxiom>&apos;NAD+ nucleotidase, cyclic ADP-ribose generating&apos; SubClassOf &apos;NAD+ nucleosidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NAD+ nucleotidase, cyclic ADP-ribose generating&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ADP-ribosyl cyclase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NAD+ nucleotidase, cyclic ADP-ribose generating&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;cyclic ADP-ribose hydrolase&apos;</deletedAxiom>
<newAxiom>&apos;NAD+ nucleotidase, cyclic ADP-ribose generating&apos; SubClassOf &apos;hydrolase activity, hydrolyzing N-glycosyl compounds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010226</classIRI>
<classLabel>response to lithium ion</classLabel>
<deletedAxiom>&apos;response to lithium ion&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;response to lithium ion&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009258</classIRI>
<classLabel>10-formyltetrahydrofolate catabolic process</classLabel>
<newAxiom>&apos;10-formyltetrahydrofolate catabolic process&apos; SubClassOf &apos;folic acid-containing compound catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009256</classIRI>
<classLabel>10-formyltetrahydrofolate metabolic process</classLabel>
<newAxiom>&apos;10-formyltetrahydrofolate metabolic process&apos; SubClassOf &apos;tetrahydrofolate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009257</classIRI>
<classLabel>10-formyltetrahydrofolate biosynthetic process</classLabel>
<newAxiom>&apos;10-formyltetrahydrofolate biosynthetic process&apos; SubClassOf &apos;tetrahydrofolate biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046202</classIRI>
<classLabel>cyanide biosynthetic process</classLabel>
<deletedAxiom>&apos;cyanide biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;cyanide biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010266</classIRI>
<classLabel>response to vitamin B1</classLabel>
<deletedAxiom>&apos;response to vitamin B1&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000828</classIRI>
<classLabel>inositol hexakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol hexakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol hexakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000829</classIRI>
<classLabel>inositol heptakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol heptakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol heptakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000827</classIRI>
<classLabel>inositol-1,3,4,5,6-pentakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol-1,3,4,5,6-pentakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol-1,3,4,5,6-pentakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000821</classIRI>
<classLabel>regulation of arginine metabolic process</classLabel>
<deletedAxiom>&apos;regulation of arginine metabolic process&apos; SubClassOf &apos;regulation of glutamine family amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of arginine metabolic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061811</classIRI>
<classLabel>ADP-ribosyl cyclase activity</classLabel>
<deletedAxiom>&apos;ADP-ribosyl cyclase activity&apos; SubClassOf &apos;cyclase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061810</classIRI>
<classLabel>NAD glycohydrolase activity</classLabel>
<deletedAxiom>&apos;NAD glycohydrolase activity&apos; SubClassOf &apos;NAD+ nucleosidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061812</classIRI>
<classLabel>cyclic ADP-ribose hydrolase</classLabel>
<deletedAxiom>&apos;cyclic ADP-ribose hydrolase&apos; SubClassOf &apos;hydrolase activity, hydrolyzing N-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034269</classIRI>
<classLabel>discadenine catabolic process</classLabel>
<deletedAxiom>&apos;discadenine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;discadenine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;discadenine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;discadenine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034267</classIRI>
<classLabel>discadenine metabolic process</classLabel>
<deletedAxiom>&apos;discadenine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;discadenine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;discadenine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034268</classIRI>
<classLabel>discadenine biosynthetic process</classLabel>
<deletedAxiom>&apos;discadenine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;discadenine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;discadenine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071247</classIRI>
<classLabel>cellular response to chromate</classLabel>
<deletedAxiom>&apos;cellular response to chromate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071246</classIRI>
<classLabel>cellular response to chlorate</classLabel>
<deletedAxiom>&apos;cellular response to chlorate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071249</classIRI>
<classLabel>cellular response to nitrate</classLabel>
<deletedAxiom>&apos;cellular response to nitrate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071239</classIRI>
<classLabel>cellular response to streptomycin</classLabel>
<deletedAxiom>&apos;cellular response to streptomycin&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to streptomycin&apos; SubClassOf &apos;cellular response to nitrogen compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071164</classIRI>
<classLabel>RNA trimethylguanosine synthase activity</classLabel>
<newAxiom>&apos;RNA trimethylguanosine synthase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010133</classIRI>
<classLabel>proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;proline catabolic process to glutamate&apos; SubClassOf &apos;amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010134</classIRI>
<classLabel>sulfate assimilation via adenylyl sulfate reduction</classLabel>
<deletedAxiom>&apos;sulfate assimilation via adenylyl sulfate reduction&apos; SubClassOf &apos;sulfate reduction&apos;</deletedAxiom>
<newAxiom>&apos;sulfate assimilation via adenylyl sulfate reduction&apos; EquivalentTo &apos;sulfate assimilation&apos; and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adenylyl-sulfate reductase activity&apos;)</newAxiom>
<newAxiom>&apos;sulfate assimilation via adenylyl sulfate reduction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adenylyl-sulfate reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010142</classIRI>
<classLabel>farnesyl diphosphate biosynthetic process, mevalonate pathway</classLabel>
<deletedAxiom>&apos;farnesyl diphosphate biosynthetic process, mevalonate pathway&apos; SubClassOf &apos;isoprenoid biosynthetic process via mevalonate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010157</classIRI>
<classLabel>response to chlorate</classLabel>
<deletedAxiom>&apos;response to chlorate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010167</classIRI>
<classLabel>response to nitrate</classLabel>
<deletedAxiom>&apos;response to nitrate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061765</classIRI>
<classLabel>perturbation by virus of host non-canonical NF-kappaB signal transduction</classLabel>
<deletedAxiom>&apos;perturbation by virus of host non-canonical NF-kappaB signal transduction&apos; SubClassOf &apos;perturbation of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061797</classIRI>
<classLabel>pH-gated chloride channel activity</classLabel>
<deletedAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;gated channel activity&apos;</deletedAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0160128</newAxiom>
<newAxiom>&apos;pH-gated chloride channel activity&apos; SubClassOf &apos;ligand-gated monoatomic anion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046177</classIRI>
<classLabel>D-gluconate catabolic process</classLabel>
<deletedAxiom>&apos;D-gluconate catabolic process&apos; SubClassOf &apos;oligosaccharide catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;D-gluconate catabolic process&apos; SubClassOf &apos;carbohydrate catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046178</classIRI>
<classLabel>D-gluconate biosynthetic process</classLabel>
<deletedAxiom>&apos;D-gluconate biosynthetic process&apos; SubClassOf &apos;oligosaccharide biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;D-gluconate biosynthetic process&apos; SubClassOf &apos;carbohydrate biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097676</classIRI>
<classLabel>histone H3-K36 dimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K36 dimethylation&apos; SubClassOf &apos;peptidyl-lysine dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K36 dimethylation&apos; SubClassOf &apos;histone H3-K36 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097692</classIRI>
<classLabel>histone H3-K4 monomethylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 monomethylation&apos; SubClassOf &apos;histone H3-K4 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097638</classIRI>
<classLabel>L-arginine import across plasma membrane</classLabel>
<deletedAxiom>&apos;L-arginine import across plasma membrane&apos; SubClassOf &apos;modified amino acid transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010034</classIRI>
<classLabel>response to acetate</classLabel>
<deletedAxiom>&apos;response to acetate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;response to acetate&apos; SubClassOf &apos;response to nitrogen compound&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009055</classIRI>
<classLabel>electron transfer activity</classLabel>
<deletedAxiom>&apos;electron transfer activity&apos; EquivalentTo &apos;oxidoreductase activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;electron transport chain&apos;)</deletedAxiom>
<deletedAxiom>&apos;electron transfer activity&apos; SubClassOf &apos;oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;electron transfer activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;electron transport chain&apos;</deletedAxiom>
<newAxiom>&apos;electron transfer activity&apos; SubClassOf &apos;molecular_function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010041</classIRI>
<classLabel>response to iron(III) ion</classLabel>
<deletedAxiom>&apos;response to iron(III) ion&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009063</classIRI>
<classLabel>amino acid catabolic process</classLabel>
<deletedAxiom>&apos;amino acid catabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009064</classIRI>
<classLabel>glutamine family amino acid metabolic process</classLabel>
<deletedAxiom>&apos;glutamine family amino acid metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutamine family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
<newAxiom>&apos;glutamine family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009067</classIRI>
<classLabel>aspartate family amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;aspartate family amino acid biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;aspartate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;aspartate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009068</classIRI>
<classLabel>aspartate family amino acid catabolic process</classLabel>
<deletedAxiom>&apos;aspartate family amino acid catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate family amino acid catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;aspartate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
<newAxiom>&apos;aspartate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009065</classIRI>
<classLabel>glutamine family amino acid catabolic process</classLabel>
<deletedAxiom>&apos;glutamine family amino acid catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamine family amino acid catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutamine family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
<newAxiom>&apos;glutamine family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009066</classIRI>
<classLabel>aspartate family amino acid metabolic process</classLabel>
<deletedAxiom>&apos;aspartate family amino acid metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;aspartate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
<newAxiom>&apos;aspartate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009069</classIRI>
<classLabel>serine family amino acid metabolic process</classLabel>
<deletedAxiom>&apos;serine family amino acid metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;serine family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;serine family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009070</classIRI>
<classLabel>serine family amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;serine family amino acid biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;serine family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;serine family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009071</classIRI>
<classLabel>serine family amino acid catabolic process</classLabel>
<deletedAxiom>&apos;serine family amino acid catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;serine family amino acid catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;serine family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170040</newAxiom>
<newAxiom>&apos;serine family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009072</classIRI>
<classLabel>aromatic amino acid metabolic process</classLabel>
<newAxiom>&apos;aromatic amino acid metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;aromatic amino acid metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009078</classIRI>
<classLabel>pyruvate family amino acid metabolic process</classLabel>
<deletedAxiom>&apos;pyruvate family amino acid metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;pyruvate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009079</classIRI>
<classLabel>pyruvate family amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;pyruvate family amino acid biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
<newAxiom>&apos;pyruvate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034013</classIRI>
<classLabel>aliphatic aldoxime dehydratase activity</classLabel>
<deletedAxiom>&apos;aliphatic aldoxime dehydratase activity&apos; SubClassOf &apos;acid-amino acid ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;aliphatic aldoxime dehydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141122</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061647</classIRI>
<classLabel>histone H3-K9 modification</classLabel>
<deletedAxiom>&apos;histone H3-K9 modification&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009081</classIRI>
<classLabel>branched-chain amino acid metabolic process</classLabel>
<newAxiom>&apos;branched-chain amino acid metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;branched-chain amino acid metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009080</classIRI>
<classLabel>pyruvate family amino acid catabolic process</classLabel>
<deletedAxiom>&apos;pyruvate family amino acid catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate family amino acid catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
<newAxiom>&apos;pyruvate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009084</classIRI>
<classLabel>glutamine family amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;glutamine family amino acid biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;glutamine family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
<newAxiom>&apos;glutamine family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009093</classIRI>
<classLabel>cysteine catabolic process</classLabel>
<deletedAxiom>&apos;cysteine catabolic process&apos; SubClassOf &apos;serine family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cysteine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;cysteine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034050</classIRI>
<classLabel>programmed cell death induced by symbiont</classLabel>
<deletedAxiom>&apos;programmed cell death induced by symbiont&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<deletedAxiom>&apos;programmed cell death induced by symbiont&apos; SubClassOf &apos;biological process involved in interaction with symbiont&apos;</deletedAxiom>
<newAxiom>&apos;programmed cell death induced by symbiont&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000284</classIRI>
<classLabel>positive regulation of amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of amino acid biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of amino acid biosynthetic process&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of amino acid biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000282</classIRI>
<classLabel>regulation of cellular amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of cellular amino acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cellular amino acid biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of cellular amino acid biosynthetic process&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000283</classIRI>
<classLabel>negative regulation of amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of amino acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of amino acid biosynthetic process&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of amino acid biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000211</classIRI>
<classLabel>regulation of glutamate metabolic process</classLabel>
<deletedAxiom>&apos;regulation of glutamate metabolic process&apos; SubClassOf &apos;regulation of amide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000212</classIRI>
<classLabel>negative regulation of glutamate metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate metabolic process&apos; SubClassOf &apos;negative regulation of amide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glutamate metabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of glutamate metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000215</classIRI>
<classLabel>negative regulation of proline metabolic process</classLabel>
<newAxiom>&apos;negative regulation of proline metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of proline metabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000216</classIRI>
<classLabel>positive regulation of proline metabolic process</classLabel>
<newAxiom>&apos;positive regulation of proline metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of proline metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000213</classIRI>
<classLabel>positive regulation of glutamate metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate metabolic process&apos; SubClassOf &apos;positive regulation of amide metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glutamate metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of glutamate metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000514</classIRI>
<classLabel>3-sulfino-L-alanine: proton, glutamate antiporter activity</classLabel>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;3-sulfino-L-alanine: proton, glutamate antiporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000515</classIRI>
<classLabel>aspartate:glutamate, proton antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061529</classIRI>
<classLabel>epinephrine secretion, neurotransmission</classLabel>
<deletedAxiom>&apos;epinephrine secretion, neurotransmission&apos; SubClassOf &apos;catecholamine secretion, neurotransmission&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine secretion, neurotransmission&apos; SubClassOf &apos;neurotransmitter secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061543</classIRI>
<classLabel>3-demethylubiquinol-6 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinol-6 3-O-methyltransferase activity&apos; SubClassOf &apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061542</classIRI>
<classLabel>3-demethylubiquinol-n 3-O-methyltransferase activity</classLabel>
<newAxiom>&apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ubiquinone biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061459</classIRI>
<classLabel>L-arginine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transporter activity&apos; SubClassOf &apos;modified amino acid transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097466</classIRI>
<classLabel>ubiquitin-dependent glycoprotein ERAD pathway</classLabel>
<deletedAxiom>&apos;ubiquitin-dependent glycoprotein ERAD pathway&apos; SubClassOf &apos;ubiquitin-dependent ERAD pathway&apos;</deletedAxiom>
<newAxiom>&apos;ubiquitin-dependent glycoprotein ERAD pathway&apos; SubClassOf &apos;ERAD pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036444</classIRI>
<classLabel>calcium import into the mitochondrion</classLabel>
<deletedAxiom>&apos;calcium import into the mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;calcium import into the mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061359</classIRI>
<classLabel>regulation of Wnt signaling pathway by Wnt protein secretion</classLabel>
<deletedAxiom>&apos;regulation of Wnt signaling pathway by Wnt protein secretion&apos; SubClassOf &apos;Wnt protein secretion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt signaling pathway by Wnt protein secretion&apos; EquivalentTo &apos;Wnt protein secretion&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;Wnt signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of Wnt signaling pathway by Wnt protein secretion&apos; SubClassOf &apos;regulation of Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097344</classIRI>
<classLabel>Rix1 complex</classLabel>
<deletedAxiom>&apos;Rix1 complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000412</classIRI>
<classLabel>histone peptidyl-prolyl isomerization</classLabel>
<deletedAxiom>&apos;histone peptidyl-prolyl isomerization&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone peptidyl-prolyl isomerization&apos; SubClassOf &apos;protein peptidyl-prolyl isomerization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160007</classIRI>
<classLabel>glutathione import into mitochondrion</classLabel>
<deletedAxiom>&apos;glutathione import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glutathione import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051958</classIRI>
<classLabel>methotrexate transport</classLabel>
<deletedAxiom>&apos;methotrexate transport&apos; SubClassOf &apos;modified amino acid transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120151</classIRI>
<classLabel>positive regulation of mitotic actomyosin contractile ring disassembly</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic actomyosin contractile ring disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;positive regulation of cytoskeleton organization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;regulation of mitotic actomyosin contractile ring disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;positive regulation of mitotic cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic actomyosin contractile ring disassembly&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic actomyosin contractile ring disassembly&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120150</classIRI>
<classLabel>regulation of mitotic actomyosin contractile ring disassembly</classLabel>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;regulation of actomyosin structure organization&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic actomyosin contractile ring disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring disassembly&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic actomyosin contractile ring disassembly&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;regulation of mitotic cytokinetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051938</classIRI>
<classLabel>L-glutamate import</classLabel>
<deletedAxiom>&apos;L-glutamate import&apos; SubClassOf &apos;amide transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036346</classIRI>
<classLabel>cellular response to L-cysteine</classLabel>
<deletedAxiom>&apos;cellular response to L-cysteine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036353</classIRI>
<classLabel>histone H2A-K119 monoubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A-K119 monoubiquitination&apos; SubClassOf &apos;histone H2A monoubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036352</classIRI>
<classLabel>histone H2A-K15 ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A-K15 ubiquitination&apos; SubClassOf &apos;histone H2A ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036351</classIRI>
<classLabel>histone H2A-K13 ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A-K13 ubiquitination&apos; SubClassOf &apos;histone H2A ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036280</classIRI>
<classLabel>cellular response to L-canavanine</classLabel>
<deletedAxiom>&apos;cellular response to L-canavanine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048250</classIRI>
<classLabel>iron import into the mitochondrion</classLabel>
<deletedAxiom>&apos;iron import into the mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;iron import into the mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036272</classIRI>
<classLabel>response to gemcitabine</classLabel>
<deletedAxiom>&apos;response to gemcitabine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061293</classIRI>
<classLabel>canonical Wnt signaling pathway involved in mesonephric nephron development</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in mesonephric nephron development&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in mesonephros development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in mesonephric nephron development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesonephric nephron development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in mesonephric nephron development&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mesonephric nephron development&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061291</classIRI>
<classLabel>canonical Wnt signaling pathway involved in ureteric bud branching</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in ureteric bud branching&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;branching involved in ureteric bud morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in ureteric bud branching&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in mesonephros development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in ureteric bud branching&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;branching involved in ureteric bud morphogenesis&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in ureteric bud branching&apos; SubClassOf &apos;canonical Wnt signaling pathway involved in metanephric kidney development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061290</classIRI>
<classLabel>canonical Wnt signaling pathway involved in metanephric kidney development</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in metanephric kidney development&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;metanephros development&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in metanephric kidney development&apos; SubClassOf &apos;Wnt signaling pathway involved in kidney development&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in metanephric kidney development&apos; SubClassOf &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in metanephric kidney development&apos; SubClassOf &apos;cell-cell signaling involved in metanephros development&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097290</classIRI>
<classLabel>alpha-ribazole biosynthetic process</classLabel>
<deletedAxiom>&apos;alpha-ribazole biosynthetic process&apos; SubClassOf &apos;alpha-ribazole metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-ribazole biosynthetic process&apos; SubClassOf &apos;heterocycle biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-ribazole biosynthetic process&apos; SubClassOf &apos;glycosyl compound biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-ribazole biosynthetic process&apos; SubClassOf &apos;organic cyclic compound biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-ribazole biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097295</classIRI>
<classLabel>morphine biosynthetic process</classLabel>
<deletedAxiom>&apos;morphine biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000319</classIRI>
<classLabel>sulfite transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sulfite transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097253</classIRI>
<classLabel>beta-hydroxybutyrate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;beta-hydroxybutyrate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120028</classIRI>
<classLabel>negative regulation of osmosensory signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of osmosensory signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;osmosensory signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling pathway&apos; SubClassOf &apos;regulation of osmosensory signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling pathway&apos; SubClassOf &apos;negative regulation of intracellular signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;osmosensory signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120027</classIRI>
<classLabel>regulation of osmosensory signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of osmosensory signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;osmosensory signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;osmosensory signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling pathway&apos; SubClassOf &apos;regulation of cellular response to osmotic stress&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling pathway&apos; SubClassOf &apos;regulation of intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036210</classIRI>
<classLabel>protein modification process in another organism</classLabel>
<deletedAxiom>&apos;protein modification process in another organism&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051873</classIRI>
<classLabel>killing by host of symbiont cells</classLabel>
<deletedAxiom>&apos;killing by host of symbiont cells&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;killing by host of symbiont cells&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048242</classIRI>
<classLabel>epinephrine secretion</classLabel>
<deletedAxiom>&apos;epinephrine secretion&apos; SubClassOf &apos;catecholamine secretion&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine secretion&apos; SubClassOf &apos;secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048241</classIRI>
<classLabel>epinephrine transport</classLabel>
<deletedAxiom>&apos;epinephrine transport&apos; SubClassOf &apos;catecholamine transport&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine transport&apos; SubClassOf &apos;transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036256</classIRI>
<classLabel>cellular response to methylamine</classLabel>
<deletedAxiom>&apos;cellular response to methylamine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036255</classIRI>
<classLabel>response to methylamine</classLabel>
<deletedAxiom>&apos;response to methylamine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051870</classIRI>
<classLabel>methotrexate binding</classLabel>
<deletedAxiom>&apos;methotrexate binding&apos; SubClassOf &apos;modified amino acid binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097184</classIRI>
<classLabel>response to azide</classLabel>
<deletedAxiom>&apos;response to azide&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097185</classIRI>
<classLabel>cellular response to azide</classLabel>
<deletedAxiom>&apos;cellular response to azide&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097198</classIRI>
<classLabel>histone H3-K36 trimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K36 trimethylation&apos; SubClassOf &apos;histone H3-K36 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K36 trimethylation&apos; SubClassOf &apos;peptidyl-lysine trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000620</classIRI>
<classLabel>positive regulation of histone H4-K16 acetylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H4-K16 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H4-K16 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H4-K16 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H4-K16 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H4-K16 acetylation&apos; SubClassOf &apos;positive regulation of histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904052</classIRI>
<classLabel>negative regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of establishment of protein localization&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</newAxiom>
<newAxiom>&apos;negative regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904051</classIRI>
<classLabel>regulation of protein targeting to vacuole involved in autophagy</classLabel>
<newAxiom>&apos;regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
<newAxiom>&apos;regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904053</classIRI>
<classLabel>positive regulation of protein targeting to vacuole involved in autophagy</classLabel>
<deletedAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of establishment of protein localization&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;positive regulation of protein targeting to vacuole involved in autophagy&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000617</classIRI>
<classLabel>positive regulation of histone H3-K9 acetylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K9 acetylation&apos; SubClassOf &apos;regulation of histone H3-K9 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 acetylation&apos; SubClassOf &apos;positive regulation of histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000615</classIRI>
<classLabel>regulation of histone H3-K9 acetylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K9 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 acetylation&apos; SubClassOf &apos;regulation of histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000616</classIRI>
<classLabel>negative regulation of histone H3-K9 acetylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K9 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 acetylation&apos; SubClassOf &apos;negative regulation of histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 acetylation&apos; SubClassOf &apos;regulation of histone H3-K9 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904187</classIRI>
<classLabel>regulation of transformation of host cell by virus</classLabel>
<deletedAxiom>&apos;regulation of transformation of host cell by virus&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048108</classIRI>
<classLabel>peptide cross-linking via 4-amino-3-isothiazolidinone</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 4-amino-3-isothiazolidinone&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 4-amino-3-isothiazolidinone&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036124</classIRI>
<classLabel>histone H3-K9 trimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 trimethylation&apos; SubClassOf &apos;peptidyl-lysine trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K9 trimethylation&apos; SubClassOf &apos;histone H3-K9 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036123</classIRI>
<classLabel>histone H3-K9 dimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 dimethylation&apos; SubClassOf &apos;peptidyl-lysine dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K9 dimethylation&apos; SubClassOf &apos;histone H3-K9 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051766</classIRI>
<classLabel>inositol trisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol trisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol trisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051765</classIRI>
<classLabel>inositol tetrakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol tetrakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol tetrakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051740</classIRI>
<classLabel>ethylene binding</classLabel>
<deletedAxiom>&apos;ethylene binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;ethylene binding&apos; SubClassOf &apos;alkene binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048109</classIRI>
<classLabel>peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine&apos; SubClassOf &apos;peptide cross-linking via 4-amino-3-isothiazolidinone&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099636</classIRI>
<classLabel>cytoplasmic streaming</classLabel>
<deletedAxiom>&apos;cytoplasmic streaming&apos; SubClassOf &apos;cytosolic transport&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic streaming&apos; SubClassOf &apos;intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048038</classIRI>
<classLabel>quinone binding</classLabel>
<deletedAxiom>&apos;quinone binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;quinone binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000165</classIRI>
<classLabel>MAPK cascade</classLabel>
<deletedAxiom>&apos;MAPK cascade&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000161</classIRI>
<classLabel>osmosensory signaling MAPK cascade</classLabel>
<deletedAxiom>&apos;osmosensory signaling MAPK cascade&apos; SubClassOf &apos;stress-activated MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;osmosensory signaling MAPK cascade&apos; SubClassOf &apos;osmosensory signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000162</classIRI>
<classLabel>tryptophan biosynthetic process</classLabel>
<newAxiom>&apos;tryptophan biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036088</classIRI>
<classLabel>D-serine catabolic process</classLabel>
<deletedAxiom>&apos;D-serine catabolic process&apos; SubClassOf &apos;serine family amino acid catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061087</classIRI>
<classLabel>positive regulation of histone H3-K27 methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K27 methylation&apos; SubClassOf &apos;regulation of histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 methylation&apos; SubClassOf &apos;positive regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K27 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061086</classIRI>
<classLabel>negative regulation of histone H3-K27 methylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K27 methylation&apos; SubClassOf &apos;regulation of histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 methylation&apos; SubClassOf &apos;negative regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K27 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061085</classIRI>
<classLabel>regulation of histone H3-K27 methylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K27 methylation&apos; SubClassOf &apos;regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K27 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K27 methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K27 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K27 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097043</classIRI>
<classLabel>histone H3-K56 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K56 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097052</classIRI>
<classLabel>L-kynurenine metabolic process</classLabel>
<newAxiom>&apos;L-kynurenine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097053</classIRI>
<classLabel>L-kynurenine catabolic process</classLabel>
<deletedAxiom>&apos;L-kynurenine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;L-kynurenine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-kynurenine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;L-kynurenine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085034</classIRI>
<classLabel>symbiont-mediated suppression of host canonical NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host canonical NF-kappaB cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097068</classIRI>
<classLabel>response to thyroxine</classLabel>
<deletedAxiom>&apos;response to thyroxine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097069</classIRI>
<classLabel>cellular response to thyroxine stimulus</classLabel>
<deletedAxiom>&apos;cellular response to thyroxine stimulus&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085017</classIRI>
<classLabel>entry into host cell by a symbiont-containing vacuole</classLabel>
<deletedAxiom>&apos;entry into host cell by a symbiont-containing vacuole&apos; SubClassOf &apos;entry into host&apos;</deletedAxiom>
<newAxiom>&apos;entry into host cell by a symbiont-containing vacuole&apos; SubClassOf &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097079</classIRI>
<classLabel>selenite:proton symporter activity</classLabel>
<deletedAxiom>&apos;selenite:proton symporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990212</classIRI>
<classLabel>positive regulation by symbiont of ethylene levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of ethylene levels in host&apos; SubClassOf &apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of ethylene levels in host&apos; SubClassOf &apos;modulation by symbiont of ethylene levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990213</classIRI>
<classLabel>negative regulation by symbiont of salicylic acid levels in host</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of salicylic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of salicylic acid levels in host&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of salicylic acid levels in host&apos; SubClassOf &apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990210</classIRI>
<classLabel>positive regulation by symbiont of indole acetic acid levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of indole acetic acid levels in host&apos; SubClassOf &apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of indole acetic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of indole acetic acid levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990211</classIRI>
<classLabel>positive regulation by symbiont of jasmonic acid levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of jasmonic acid levels in host&apos; SubClassOf &apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of jasmonic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of jasmonic acid levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000901</classIRI>
<classLabel>cyclodextrin catabolic process</classLabel>
<deletedAxiom>&apos;cyclodextrin catabolic process&apos; SubClassOf &apos;glucan catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cyclodextrin catabolic process&apos; SubClassOf &apos;dextrin catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990274</classIRI>
<classLabel>mitotic actomyosin contractile ring disassembly</classLabel>
<deletedAxiom>&apos;mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;actomyosin contractile ring disassembly&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic actomyosin contractile ring disassembly&apos; SubClassOf &apos;mitotic cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic actomyosin contractile ring disassembly&apos; EquivalentTo &apos;actomyosin contractile ring disassembly&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cytokinesis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990258</classIRI>
<classLabel>histone glutamine methylation</classLabel>
<deletedAxiom>&apos;histone glutamine methylation&apos; SubClassOf &apos;histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone glutamine methylation&apos; SubClassOf &apos;peptidyl-glutamine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990223</classIRI>
<classLabel>positive regulation by symbiont of cytokinin levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of cytokinin levels in host&apos; SubClassOf &apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990218</classIRI>
<classLabel>positive regulation by symbiont of abscisic acid levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of abscisic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of abscisic acid levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051625</classIRI>
<classLabel>epinephrine uptake</classLabel>
<deletedAxiom>&apos;epinephrine uptake&apos; SubClassOf &apos;catecholamine uptake&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051568</classIRI>
<classLabel>histone H3-K4 methylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051567</classIRI>
<classLabel>histone H3-K9 methylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K9 methylation&apos; SubClassOf &apos;histone H3-K9 modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051569</classIRI>
<classLabel>regulation of histone H3-K4 methylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K4 methylation&apos; SubClassOf &apos;regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K4 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K4 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K4 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051571</classIRI>
<classLabel>positive regulation of histone H3-K4 methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K4 methylation&apos; SubClassOf &apos;positive regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K4 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K4 methylation&apos; SubClassOf &apos;regulation of histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K4 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K4 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051570</classIRI>
<classLabel>regulation of histone H3-K9 methylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K9 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 methylation&apos; SubClassOf &apos;regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051573</classIRI>
<classLabel>negative regulation of histone H3-K9 methylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K9 methylation&apos; SubClassOf &apos;negative regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 methylation&apos; SubClassOf &apos;regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051572</classIRI>
<classLabel>negative regulation of histone H3-K4 methylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K4 methylation&apos; SubClassOf &apos;negative regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K4 methylation&apos; SubClassOf &apos;regulation of histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K4 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K4 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K4 methylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051540</classIRI>
<classLabel>metal cluster binding</classLabel>
<deletedAxiom>&apos;metal cluster binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;metal cluster binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000053</classIRI>
<classLabel>argininosuccinate metabolic process</classLabel>
<deletedAxiom>&apos;argininosuccinate metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;argininosuccinate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;argininosuccinate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000052</classIRI>
<classLabel>citrulline metabolic process</classLabel>
<newAxiom>&apos;citrulline metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000035</classIRI>
<classLabel>acyl binding</classLabel>
<deletedAxiom>&apos;acyl binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;acyl binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051574</classIRI>
<classLabel>positive regulation of histone H3-K9 methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K9 methylation&apos; SubClassOf &apos;regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 methylation&apos; SubClassOf &apos;positive regulation of histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051592</classIRI>
<classLabel>response to calcium ion</classLabel>
<deletedAxiom>&apos;response to calcium ion&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to calcium ion&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;response to calcium ion&apos; SubClassOf &apos;response to organic substance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099587</classIRI>
<classLabel>inorganic ion import across plasma membrane</classLabel>
<deletedAxiom>&apos;inorganic ion import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000890</classIRI>
<classLabel>cellodextrin catabolic process</classLabel>
<deletedAxiom>&apos;cellodextrin catabolic process&apos; SubClassOf &apos;glucan catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellodextrin catabolic process&apos; SubClassOf &apos;dextrin catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904313</classIRI>
<classLabel>response to methamphetamine hydrochloride</classLabel>
<deletedAxiom>&apos;response to methamphetamine hydrochloride&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904314</classIRI>
<classLabel>cellular response to methamphetamine hydrochloride</classLabel>
<deletedAxiom>&apos;cellular response to methamphetamine hydrochloride&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904379</classIRI>
<classLabel>protein localization to cytosolic proteasome complex involved in ERAD pathway</classLabel>
<deletedAxiom>&apos;protein localization to cytosolic proteasome complex involved in ERAD pathway&apos; EquivalentTo &apos;protein localization to cytosolic proteasome complex&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ERAD pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;protein localization to cytosolic proteasome complex involved in ERAD pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;protein localization to cytosolic proteasome complex involved in ERAD pathway&apos; SubClassOf &apos;protein localization to cytosolic proteasome complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905827</classIRI>
<classLabel>positive regulation of selenocysteine metabolic process</classLabel>
<newAxiom>&apos;positive regulation of selenocysteine metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of selenocysteine metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905826</classIRI>
<classLabel>negative regulation of selenocysteine metabolic process</classLabel>
<newAxiom>&apos;negative regulation of selenocysteine metabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of selenocysteine metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051379</classIRI>
<classLabel>epinephrine binding</classLabel>
<deletedAxiom>&apos;epinephrine binding&apos; SubClassOf &apos;catecholamine binding&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine binding&apos; SubClassOf &apos;hormone binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051378</classIRI>
<classLabel>serotonin binding</classLabel>
<newAxiom>&apos;serotonin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905794</classIRI>
<classLabel>response to puromycin</classLabel>
<deletedAxiom>&apos;response to puromycin&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905795</classIRI>
<classLabel>cellular response to puromycin</classLabel>
<deletedAxiom>&apos;cellular response to puromycin&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903135</classIRI>
<classLabel>cupric ion binding</classLabel>
<deletedAxiom>&apos;cupric ion binding&apos; SubClassOf &apos;sulfur compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051381</classIRI>
<classLabel>histamine binding</classLabel>
<newAxiom>&apos;histamine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075343</classIRI>
<classLabel>modulation by symbiont of abscisic acid levels in host</classLabel>
<deletedAxiom>&apos;modulation by symbiont of abscisic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903196</classIRI>
<classLabel>negative regulation of L-dopa biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903195</classIRI>
<classLabel>regulation of L-dopa biosynthetic process</classLabel>
<newAxiom>&apos;regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903197</classIRI>
<classLabel>positive regulation of L-dopa biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903185</classIRI>
<classLabel>L-dopa biosynthetic process</classLabel>
<deletedAxiom>&apos;L-dopa biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-dopa biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;L-dopa biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903184</classIRI>
<classLabel>L-dopa metabolic process</classLabel>
<deletedAxiom>&apos;L-dopa metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-dopa metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;L-dopa metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110141</classIRI>
<classLabel>L-glutamate import into mitochondrion</classLabel>
<deletedAxiom>&apos;L-glutamate import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;L-glutamate import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004970</classIRI>
<classLabel>glutamate-gated receptor activity</classLabel>
<deletedAxiom>&apos;glutamate-gated receptor activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate-gated receptor activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905949</classIRI>
<classLabel>negative regulation of calcium ion import across plasma membrane</classLabel>
<newAxiom>&apos;negative regulation of calcium ion import across plasma membrane&apos; SubClassOf &apos;negative regulation of calcium ion import&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903248</classIRI>
<classLabel>regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of citrulline biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of citrulline biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of citrulline biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903249</classIRI>
<classLabel>negative regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of citrulline biosynthetic process&apos; SubClassOf &apos;negative regulation of amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of citrulline biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of citrulline biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of citrulline biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903250</classIRI>
<classLabel>positive regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of citrulline biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of citrulline biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of citrulline biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of citrulline biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903253</classIRI>
<classLabel>hercynylcysteine sulfoxide biosynthetic process</classLabel>
<deletedAxiom>&apos;hercynylcysteine sulfoxide biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;hercynylcysteine sulfoxide biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903252</classIRI>
<classLabel>hercynylcysteine sulfoxide metabolic process</classLabel>
<deletedAxiom>&apos;hercynylcysteine sulfoxide metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;hercynylcysteine sulfoxide metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903255</classIRI>
<classLabel>hercynylselenocysteine biosynthetic process</classLabel>
<deletedAxiom>&apos;hercynylselenocysteine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;hercynylselenocysteine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903254</classIRI>
<classLabel>hercynylselenocysteine metabolic process</classLabel>
<deletedAxiom>&apos;hercynylselenocysteine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;hercynylselenocysteine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903264</classIRI>
<classLabel>nitrate reductase activity involved in anaerobic electron transport chain</classLabel>
<deletedAxiom>&apos;nitrate reductase activity involved in anaerobic electron transport chain&apos; SubClassOf &apos;electron transfer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903268</classIRI>
<classLabel>positive regulation of ornithine catabolic process</classLabel>
<newAxiom>&apos;positive regulation of ornithine catabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903267</classIRI>
<classLabel>negative regulation of ornithine catabolic process</classLabel>
<newAxiom>&apos;negative regulation of ornithine catabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004848</classIRI>
<classLabel>ureidoglycolate hydrolase activity</classLabel>
<deletedAxiom>&apos;ureidoglycolate hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines&apos;</deletedAxiom>
<newAxiom>&apos;ureidoglycolate hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002195</classIRI>
<classLabel>2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis</classLabel>
<deletedAxiom>&apos;2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis&apos; SubClassOf &apos;tRNA modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903329</classIRI>
<classLabel>regulation of iron-sulfur cluster assembly</classLabel>
<deletedAxiom>&apos;regulation of iron-sulfur cluster assembly&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0089718</classIRI>
<classLabel>amino acid import across plasma membrane</classLabel>
<deletedAxiom>&apos;amino acid import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903330</classIRI>
<classLabel>negative regulation of iron-sulfur cluster assembly</classLabel>
<deletedAxiom>&apos;negative regulation of iron-sulfur cluster assembly&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903331</classIRI>
<classLabel>positive regulation of iron-sulfur cluster assembly</classLabel>
<deletedAxiom>&apos;positive regulation of iron-sulfur cluster assembly&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075135</classIRI>
<classLabel>symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075114</classIRI>
<classLabel>symbiont-mediated suppression of host transmembrane receptor-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host transmembrane receptor-mediated signal transduction&apos; SubClassOf &apos;perturbation of host transmembrane receptor-mediated signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host transmembrane receptor-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host receptor-mediated signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075118</classIRI>
<classLabel>perturbation of host G protein-coupled receptor signal transduction pathway</classLabel>
<deletedAxiom>&apos;perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf &apos;perturbation of host transmembrane receptor-mediated signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf &apos;symbiont-mediated activation of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf &apos;perturbation of host receptor-mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075120</classIRI>
<classLabel>symbiont-mediated suppression of host G protein-coupled receptor signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099119</classIRI>
<classLabel>3-demethylubiquinol-8 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinol-8 3-O-methyltransferase activity&apos; SubClassOf &apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075112</classIRI>
<classLabel>perturbation of host transmembrane receptor-mediated signal transduction</classLabel>
<deletedAxiom>&apos;perturbation of host transmembrane receptor-mediated signal transduction&apos; SubClassOf &apos;perturbation of host receptor-mediated signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075111</classIRI>
<classLabel>symbiont-mediated suppression of host receptor-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host receptor-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099093</classIRI>
<classLabel>calcium export from the mitochondrion</classLabel>
<newAxiom>&apos;calcium export from the mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170037</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099018</classIRI>
<classLabel>evasion by virus of host restriction-modification system</classLabel>
<deletedAxiom>&apos;evasion by virus of host restriction-modification system&apos; SubClassOf &apos;virus-mediated perturbation of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;evasion by virus of host restriction-modification system&apos; SubClassOf &apos;evasion of host innate immune recognition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099046</classIRI>
<classLabel>clearance of foreign intracellular nucleic acids</classLabel>
<deletedAxiom>&apos;clearance of foreign intracellular nucleic acids&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;clearance of foreign intracellular nucleic acids&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004791</classIRI>
<classLabel>thioredoxin-disulfide reductase (NADP) activity</classLabel>
<deletedAxiom>&apos;thioredoxin-disulfide reductase (NADP) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;thioredoxin-disulfide reductase (NADP) activity&apos; SubClassOf &apos;protein-disulfide reductase (NAD(P)) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038008</classIRI>
<classLabel>TRAF-mediated signal transduction</classLabel>
<deletedAxiom>&apos;TRAF-mediated signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014047</classIRI>
<classLabel>glutamate secretion</classLabel>
<deletedAxiom>&apos;glutamate secretion&apos; SubClassOf &apos;amide transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903425</classIRI>
<classLabel>fluoride transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;fluoride transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0014060</classIRI>
<classLabel>regulation of epinephrine secretion</classLabel>
<deletedAxiom>&apos;regulation of epinephrine secretion&apos; SubClassOf &apos;regulation of catecholamine secretion&apos;</deletedAxiom>
<newAxiom>&apos;regulation of epinephrine secretion&apos; SubClassOf &apos;regulation of secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038035</classIRI>
<classLabel>G protein-coupled receptor signaling in absence of ligand</classLabel>
<deletedAxiom>&apos;G protein-coupled receptor signaling in absence of ligand&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;G protein-coupled receptor signaling in absence of ligand&apos; SubClassOf &apos;adenylate cyclase-activating G protein-coupled receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038066</classIRI>
<classLabel>p38MAPK cascade</classLabel>
<deletedAxiom>&apos;p38MAPK cascade&apos; SubClassOf &apos;stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;p38MAPK cascade&apos; SubClassOf &apos;MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038061</classIRI>
<classLabel>non-canonical NF-kappaB signal transduction</classLabel>
<deletedAxiom>&apos;non-canonical NF-kappaB signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;non-canonical NF-kappaB signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038058</classIRI>
<classLabel>TNFSF11 receptor activity</classLabel>
<deletedAxiom>&apos;TNFSF11 receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;TNFSF11-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;TNFSF11 receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;TNFSF11 binding&apos;</deletedAxiom>
<deletedAxiom>&apos;TNFSF11 receptor activity&apos; SubClassOf &apos;tumor necrosis factor receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903493</classIRI>
<classLabel>response to clopidogrel</classLabel>
<deletedAxiom>&apos;response to clopidogrel&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099001</classIRI>
<classLabel>viral genome ejection through host cell envelope, long flexible tail mechanism</classLabel>
<deletedAxiom>&apos;viral genome ejection through host cell envelope, long flexible tail mechanism&apos; SubClassOf &apos;transport of virus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099002</classIRI>
<classLabel>viral genome ejection through host cell envelope, short tail mechanism</classLabel>
<deletedAxiom>&apos;viral genome ejection through host cell envelope, short tail mechanism&apos; SubClassOf &apos;transport of virus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099016</classIRI>
<classLabel>evasion by virus of DNA end degradation</classLabel>
<deletedAxiom>&apos;evasion by virus of DNA end degradation&apos; SubClassOf &apos;virus-mediated perturbation of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;evasion by virus of DNA end degradation&apos; SubClassOf &apos;evasion of host innate immune recognition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016601</classIRI>
<classLabel>Rac protein signal transduction</classLabel>
<deletedAxiom>&apos;Rac protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Rac protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903649</classIRI>
<classLabel>regulation of cytoplasmic transport</classLabel>
<deletedAxiom>&apos;regulation of cytoplasmic transport&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytosolic transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cytoplasmic transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytosolic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cytoplasmic transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004668</classIRI>
<classLabel>protein-arginine deiminase activity</classLabel>
<deletedAxiom>&apos;protein-arginine deiminase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903558</classIRI>
<classLabel>3-cyano-L-alanine metabolic process</classLabel>
<deletedAxiom>&apos;3-cyano-L-alanine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;3-cyano-L-alanine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903559</classIRI>
<classLabel>3-cyano-L-alanine catabolic process</classLabel>
<deletedAxiom>&apos;3-cyano-L-alanine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;3-cyano-L-alanine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;3-cyano-L-alanine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;3-cyano-L-alanine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903560</classIRI>
<classLabel>3-cyano-L-alanine biosynthetic process</classLabel>
<deletedAxiom>&apos;3-cyano-L-alanine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;3-cyano-L-alanine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;3-cyano-L-alanine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016578</classIRI>
<classLabel>histone deubiquitination</classLabel>
<deletedAxiom>&apos;histone deubiquitination&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone deubiquitination&apos; SubClassOf &apos;protein deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016577</classIRI>
<classLabel>histone demethylation</classLabel>
<deletedAxiom>&apos;histone demethylation&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone demethylation&apos; SubClassOf &apos;protein demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016575</classIRI>
<classLabel>histone deacetylation</classLabel>
<deletedAxiom>&apos;histone deacetylation&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone deacetylation&apos; SubClassOf &apos;protein deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016574</classIRI>
<classLabel>histone ubiquitination</classLabel>
<deletedAxiom>&apos;histone ubiquitination&apos; SubClassOf &apos;protein ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;histone ubiquitination&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016573</classIRI>
<classLabel>histone acetylation</classLabel>
<deletedAxiom>&apos;histone acetylation&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone acetylation&apos; SubClassOf &apos;internal peptidyl-lysine acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016571</classIRI>
<classLabel>histone methylation</classLabel>
<deletedAxiom>&apos;histone methylation&apos; SubClassOf &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone methylation&apos; SubClassOf &apos;protein methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016570</classIRI>
<classLabel>histone modification</classLabel>
<deletedAxiom>&apos;histone modification&apos; SubClassOf &apos;post-translational protein modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903545</classIRI>
<classLabel>cellular response to butyrate</classLabel>
<deletedAxiom>&apos;cellular response to butyrate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903544</classIRI>
<classLabel>response to butyrate</classLabel>
<deletedAxiom>&apos;response to butyrate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016595</classIRI>
<classLabel>glutamate binding</classLabel>
<deletedAxiom>&apos;glutamate binding&apos; SubClassOf &apos;amide binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903585</classIRI>
<classLabel>negative regulation of histone deubiquitination</classLabel>
<deletedAxiom>&apos;negative regulation of histone deubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deubiquitination&apos; SubClassOf &apos;regulation of histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deubiquitination&apos; SubClassOf &apos;negative regulation of protein deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903584</classIRI>
<classLabel>regulation of histone deubiquitination</classLabel>
<deletedAxiom>&apos;regulation of histone deubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deubiquitination&apos; SubClassOf &apos;regulation of protein deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deubiquitination&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903586</classIRI>
<classLabel>positive regulation of histone deubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of histone deubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deubiquitination&apos; SubClassOf &apos;positive regulation of protein deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deubiquitination&apos; SubClassOf &apos;regulation of histone deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090454</classIRI>
<classLabel>glutamate transmembrane import into vacuole</classLabel>
<deletedAxiom>&apos;glutamate transmembrane import into vacuole&apos; SubClassOf &apos;amide transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102991</classIRI>
<classLabel>myristoyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;myristoyl-CoA hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903753</classIRI>
<classLabel>negative regulation of p38MAPK cascade</classLabel>
<deletedAxiom>&apos;negative regulation of p38MAPK cascade&apos; SubClassOf &apos;negative regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of p38MAPK cascade&apos; SubClassOf &apos;negative regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901101</classIRI>
<classLabel>gramicidin S metabolic process</classLabel>
<deletedAxiom>&apos;gramicidin S metabolic process&apos; SubClassOf &apos;peptide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901102</classIRI>
<classLabel>gramicidin S catabolic process</classLabel>
<deletedAxiom>&apos;gramicidin S catabolic process&apos; SubClassOf &apos;gramicidin S metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;gramicidin S catabolic process&apos; SubClassOf &apos;peptide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901103</classIRI>
<classLabel>gramicidin S biosynthetic process</classLabel>
<deletedAxiom>&apos;gramicidin S biosynthetic process&apos; SubClassOf &apos;gramicidin S metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901010</classIRI>
<classLabel>(S)-reticuline metabolic process</classLabel>
<deletedAxiom>&apos;(S)-reticuline metabolic process&apos; SubClassOf &apos;benzyl isoquinoline alkaloid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-reticuline metabolic process&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-reticuline metabolic process&apos; SubClassOf &apos;organic hydroxy compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-reticuline metabolic process&apos; SubClassOf &apos;heterocycle metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901012</classIRI>
<classLabel>(S)-reticuline biosynthetic process</classLabel>
<deletedAxiom>&apos;(S)-reticuline biosynthetic process&apos; SubClassOf &apos;(S)-reticuline metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903651</classIRI>
<classLabel>positive regulation of cytoplasmic transport</classLabel>
<deletedAxiom>&apos;positive regulation of cytoplasmic transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cytoplasmic transport&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cytoplasmic transport&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cytosolic transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cytoplasmic transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cytosolic transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903650</classIRI>
<classLabel>negative regulation of cytoplasmic transport</classLabel>
<deletedAxiom>&apos;negative regulation of cytoplasmic transport&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cytoplasmic transport&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cytosolic transport&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cytoplasmic transport&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cytoplasmic transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cytosolic transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903652</classIRI>
<classLabel>modulation by virus of host cytoplasmic transport</classLabel>
<deletedAxiom>&apos;modulation by virus of host cytoplasmic transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytosolic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host cytoplasmic transport&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytosolic transport&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901007</classIRI>
<classLabel>(S)-scoulerine metabolic process</classLabel>
<deletedAxiom>&apos;(S)-scoulerine metabolic process&apos; SubClassOf &apos;heterocycle metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-scoulerine metabolic process&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-scoulerine metabolic process&apos; SubClassOf &apos;isoquinoline alkaloid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901009</classIRI>
<classLabel>(S)-scoulerine biosynthetic process</classLabel>
<deletedAxiom>&apos;(S)-scoulerine biosynthetic process&apos; SubClassOf &apos;(S)-scoulerine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901052</classIRI>
<classLabel>sarcosine metabolic process</classLabel>
<newAxiom>&apos;sarcosine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901053</classIRI>
<classLabel>sarcosine catabolic process</classLabel>
<newAxiom>&apos;sarcosine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901054</classIRI>
<classLabel>sarcosine biosynthetic process</classLabel>
<newAxiom>&apos;sarcosine biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;sarcosine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901055</classIRI>
<classLabel>trimethylenediamine metabolic process</classLabel>
<deletedAxiom>&apos;trimethylenediamine metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;trimethylenediamine metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;trimethylenediamine metabolic process&apos; SubClassOf &apos;polyamine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901056</classIRI>
<classLabel>trimethylenediamine catabolic process</classLabel>
<deletedAxiom>&apos;trimethylenediamine catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;trimethylenediamine catabolic process&apos; SubClassOf &apos;polyamine catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901057</classIRI>
<classLabel>trimethylenediamine biosynthetic process</classLabel>
<deletedAxiom>&apos;trimethylenediamine biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;trimethylenediamine biosynthetic process&apos; SubClassOf &apos;polyamine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901083</classIRI>
<classLabel>pyrrolizidine alkaloid metabolic process</classLabel>
<deletedAxiom>&apos;pyrrolizidine alkaloid metabolic process&apos; SubClassOf &apos;alkaloid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901085</classIRI>
<classLabel>pyrrolizidine alkaloid biosynthetic process</classLabel>
<deletedAxiom>&apos;pyrrolizidine alkaloid biosynthetic process&apos; SubClassOf &apos;pyrrolizidine alkaloid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090422</classIRI>
<classLabel>thiamine pyrophosphate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;thiamine pyrophosphate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090358</classIRI>
<classLabel>positive regulation of tryptophan metabolic process</classLabel>
<newAxiom>&apos;positive regulation of tryptophan metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of tryptophan metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090374</classIRI>
<classLabel>oligopeptide export from mitochondrion</classLabel>
<deletedAxiom>&apos;oligopeptide export from mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;oligopeptide export from mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170037</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903826</classIRI>
<classLabel>L-arginine transmembrane transport</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane transport&apos; SubClassOf &apos;modified amino acid transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903787</classIRI>
<classLabel>negative regulation of glutathione biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of glutathione biosynthetic process&apos; SubClassOf &apos;negative regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903786</classIRI>
<classLabel>regulation of glutathione biosynthetic process</classLabel>
<newAxiom>&apos;regulation of glutathione biosynthetic process&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903788</classIRI>
<classLabel>positive regulation of glutathione biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of glutathione biosynthetic process&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043970</classIRI>
<classLabel>histone H3-K9 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 acetylation&apos; SubClassOf &apos;histone H3-K9 modification&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K9 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043971</classIRI>
<classLabel>histone H3-K18 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K18 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043972</classIRI>
<classLabel>histone H3-K23 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K23 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043966</classIRI>
<classLabel>histone H3 acetylation</classLabel>
<deletedAxiom>&apos;histone H3 acetylation&apos; SubClassOf &apos;histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043967</classIRI>
<classLabel>histone H4 acetylation</classLabel>
<deletedAxiom>&apos;histone H4 acetylation&apos; SubClassOf &apos;histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043968</classIRI>
<classLabel>histone H2A acetylation</classLabel>
<deletedAxiom>&apos;histone H2A acetylation&apos; SubClassOf &apos;histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043969</classIRI>
<classLabel>histone H2B acetylation</classLabel>
<deletedAxiom>&apos;histone H2B acetylation&apos; SubClassOf &apos;histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901150</classIRI>
<classLabel>vistamycin metabolic process</classLabel>
<deletedAxiom>&apos;vistamycin metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901151</classIRI>
<classLabel>vistamycin catabolic process</classLabel>
<deletedAxiom>&apos;vistamycin catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901152</classIRI>
<classLabel>vistamycin biosynthetic process</classLabel>
<deletedAxiom>&apos;vistamycin biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004395</classIRI>
<classLabel>hexaprenyldihydroxybenzoate methyltransferase activity</classLabel>
<deletedAxiom>&apos;hexaprenyldihydroxybenzoate methyltransferase activity&apos; SubClassOf &apos;3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043984</classIRI>
<classLabel>histone H4-K16 acetylation</classLabel>
<deletedAxiom>&apos;histone H4-K16 acetylation&apos; SubClassOf &apos;histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043985</classIRI>
<classLabel>histone H4-R3 methylation</classLabel>
<deletedAxiom>&apos;histone H4-R3 methylation&apos; SubClassOf &apos;histone arginine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043980</classIRI>
<classLabel>histone H2B-K12 acetylation</classLabel>
<deletedAxiom>&apos;histone H2B-K12 acetylation&apos; SubClassOf &apos;histone H2B acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043981</classIRI>
<classLabel>histone H4-K5 acetylation</classLabel>
<deletedAxiom>&apos;histone H4-K5 acetylation&apos; SubClassOf &apos;histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043982</classIRI>
<classLabel>histone H4-K8 acetylation</classLabel>
<deletedAxiom>&apos;histone H4-K8 acetylation&apos; SubClassOf &apos;histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043983</classIRI>
<classLabel>histone H4-K12 acetylation</classLabel>
<deletedAxiom>&apos;histone H4-K12 acetylation&apos; SubClassOf &apos;histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043973</classIRI>
<classLabel>histone H3-K4 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043974</classIRI>
<classLabel>histone H3-K27 acetylation</classLabel>
<deletedAxiom>&apos;histone H3-K27 acetylation&apos; SubClassOf &apos;histone H3 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043977</classIRI>
<classLabel>histone H2A-K5 acetylation</classLabel>
<deletedAxiom>&apos;histone H2A-K5 acetylation&apos; SubClassOf &apos;histone H2A acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043979</classIRI>
<classLabel>histone H2B-K5 acetylation</classLabel>
<deletedAxiom>&apos;histone H2B-K5 acetylation&apos; SubClassOf &apos;histone H2B acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180015</classIRI>
<classLabel>nucleoside import across plasma membrane</classLabel>
<deletedAxiom>&apos;nucleoside import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090239</classIRI>
<classLabel>regulation of histone H4 acetylation</classLabel>
<deletedAxiom>&apos;regulation of histone H4 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H4 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H4 acetylation&apos; SubClassOf &apos;regulation of histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H4 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H4 acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102783</classIRI>
<classLabel>beta-carotene oxygenase activity</classLabel>
<deletedAxiom>&apos;beta-carotene oxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090226</classIRI>
<classLabel>regulation of microtubule nucleation by Ran protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of microtubule nucleation by Ran protein signal transduction&apos; EquivalentTo &apos;Ran protein signal transduction&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;microtubule nucleation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule nucleation by Ran protein signal transduction&apos; SubClassOf &apos;regulation of microtubule nucleation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule nucleation by Ran protein signal transduction&apos; SubClassOf &apos;Ran protein signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903927</classIRI>
<classLabel>response to cyanide</classLabel>
<deletedAxiom>&apos;response to cyanide&apos; SubClassOf &apos;response to organonitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to cyanide&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
<newAxiom>&apos;response to cyanide&apos; SubClassOf &apos;response to organic substance&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903928</classIRI>
<classLabel>cellular response to cyanide</classLabel>
<deletedAxiom>&apos;cellular response to cyanide&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to cyanide&apos; SubClassOf &apos;cellular response to organonitrogen compound&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to cyanide&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090240</classIRI>
<classLabel>positive regulation of histone H4 acetylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H4 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H4 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H4 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H4 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H4 acetylation&apos; SubClassOf &apos;regulation of histone H4 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H4 acetylation&apos; SubClassOf &apos;positive regulation of histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090241</classIRI>
<classLabel>negative regulation of histone H4 acetylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H4 acetylation&apos; SubClassOf &apos;regulation of histone H4 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H4 acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H4 acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H4 acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H4 acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H4 acetylation&apos; SubClassOf &apos;negative regulation of histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018901</classIRI>
<classLabel>2,4-dichlorophenoxyacetic acid metabolic process</classLabel>
<deletedAxiom>&apos;2,4-dichlorophenoxyacetic acid metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018908</classIRI>
<classLabel>organosulfide cycle</classLabel>
<deletedAxiom>&apos;organosulfide cycle&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031925</classIRI>
<classLabel>pyridoxal transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyridoxal transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031928</classIRI>
<classLabel>pyridoxine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyridoxine transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031927</classIRI>
<classLabel>pyridoxamine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyridoxamine transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901314</classIRI>
<classLabel>regulation of histone H2A K63-linked ubiquitination</classLabel>
<deletedAxiom>&apos;regulation of histone H2A K63-linked ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2A K63-linked ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;regulation of protein K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2A K63-linked ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901315</classIRI>
<classLabel>negative regulation of histone H2A K63-linked ubiquitination</classLabel>
<deletedAxiom>&apos;negative regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H2A K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H2A K63-linked ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H2A K63-linked ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;negative regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;regulation of histone H2A K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;negative regulation of protein K63-linked ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901316</classIRI>
<classLabel>positive regulation of histone H2A K63-linked ubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;positive regulation of protein K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2A K63-linked ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H2A K63-linked ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;positive regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;regulation of histone H2A K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2A K63-linked ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H2A K63-linked ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903981</classIRI>
<classLabel>enterobactin binding</classLabel>
<newAxiom>&apos;enterobactin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004320</classIRI>
<classLabel>oleoyl-[acyl-carrier-protein] hydrolase activity</classLabel>
<deletedAxiom>&apos;oleoyl-[acyl-carrier-protein] hydrolase activity&apos; SubClassOf &apos;acyl-[acyl-carrier-protein] hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018864</classIRI>
<classLabel>acetylene metabolic process</classLabel>
<deletedAxiom>&apos;acetylene metabolic process&apos; SubClassOf &apos;organometal metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018871</classIRI>
<classLabel>1-aminocyclopropane-1-carboxylate metabolic process</classLabel>
<newAxiom>&apos;1-aminocyclopropane-1-carboxylate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901238</classIRI>
<classLabel>ABC-type tungstate transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type tungstate transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043820</classIRI>
<classLabel>propionyl-CoA dehydrogenase activity</classLabel>
<deletedAxiom>&apos;propionyl-CoA dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901239</classIRI>
<classLabel>malonate(1-) transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;malonate(1-) transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043826</classIRI>
<classLabel>sulfur oxygenase reductase activity</classLabel>
<deletedAxiom>&apos;sulfur oxygenase reductase activity&apos; SubClassOf &apos;oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016226</classIRI>
<classLabel>iron-sulfur cluster assembly</classLabel>
<deletedAxiom>&apos;iron-sulfur cluster assembly&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043841</classIRI>
<classLabel>(S)-lactate 2-kinase activity</classLabel>
<deletedAxiom>&apos;(S)-lactate 2-kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;(S)-lactate 2-kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043872</classIRI>
<classLabel>lysine:cadaverine antiporter activity</classLabel>
<deletedAxiom>&apos;lysine:cadaverine antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043879</classIRI>
<classLabel>glycolate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;glycolate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016290</classIRI>
<classLabel>palmitoyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;palmitoyl-CoA hydrolase activity&apos; SubClassOf &apos;acyl-CoA hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016296</classIRI>
<classLabel>palmitoyl-[acyl-carrier-protein] hydrolase activity</classLabel>
<deletedAxiom>&apos;palmitoyl-[acyl-carrier-protein] hydrolase activity&apos; SubClassOf &apos;acyl-[acyl-carrier-protein] hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016295</classIRI>
<classLabel>myristoyl-[acyl-carrier-protein] hydrolase activity</classLabel>
<deletedAxiom>&apos;myristoyl-[acyl-carrier-protein] hydrolase activity&apos; SubClassOf &apos;acyl-[acyl-carrier-protein] hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901425</classIRI>
<classLabel>response to formic acid</classLabel>
<deletedAxiom>&apos;response to formic acid&apos; SubClassOf &apos;response to nitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to formic acid&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006816</classIRI>
<classLabel>calcium ion transport</classLabel>
<deletedAxiom>&apos;calcium ion transport&apos; SubClassOf &apos;organic substance transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018814</classIRI>
<classLabel>phenylacetaldoxime dehydratase activity</classLabel>
<deletedAxiom>&apos;phenylacetaldoxime dehydratase activity&apos; SubClassOf &apos;acid-amino acid ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;phenylacetaldoxime dehydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141122</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006833</classIRI>
<classLabel>water transport</classLabel>
<deletedAxiom>&apos;water transport&apos; SubClassOf &apos;organic substance transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006846</classIRI>
<classLabel>acetate transport</classLabel>
<deletedAxiom>&apos;acetate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006850</classIRI>
<classLabel>mitochondrial pyruvate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial pyruvate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial pyruvate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006851</classIRI>
<classLabel>mitochondrial calcium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial calcium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial calcium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006749</classIRI>
<classLabel>glutathione metabolic process</classLabel>
<deletedAxiom>&apos;glutathione metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutathione metabolic process&apos; SubClassOf &apos;cellular modified amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutathione metabolic process&apos; SubClassOf &apos;peptide metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutathione metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901370</classIRI>
<classLabel>response to glutathione</classLabel>
<deletedAxiom>&apos;response to glutathione&apos; SubClassOf &apos;response to organic substance&apos;</deletedAxiom>
<newAxiom>&apos;response to glutathione&apos; SubClassOf &apos;response to peptide&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006751</classIRI>
<classLabel>glutathione catabolic process</classLabel>
<deletedAxiom>&apos;glutathione catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutathione catabolic process&apos; SubClassOf &apos;peptide catabolic process&apos;</newAxiom>
<newAxiom>&apos;glutathione catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</newAxiom>
<newAxiom>&apos;glutathione catabolic process&apos; SubClassOf &apos;cellular modified amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006750</classIRI>
<classLabel>glutathione biosynthetic process</classLabel>
<newAxiom>&apos;glutathione biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;glutathione biosynthetic process&apos; SubClassOf &apos;cellular modified amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901354</classIRI>
<classLabel>response to L-canavanine</classLabel>
<deletedAxiom>&apos;response to L-canavanine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901367</classIRI>
<classLabel>response to L-cysteine</classLabel>
<deletedAxiom>&apos;response to L-cysteine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006799</classIRI>
<classLabel>polyphosphate biosynthetic process</classLabel>
<newAxiom>&apos;polyphosphate biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006798</classIRI>
<classLabel>polyphosphate catabolic process</classLabel>
<newAxiom>&apos;polyphosphate catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004164</classIRI>
<classLabel>diphthine synthase activity</classLabel>
<newAxiom>&apos;diphthine synthase activity&apos; SubClassOf &apos;protein methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043734</classIRI>
<classLabel>DNA-N1-methyladenine dioxygenase activity</classLabel>
<deletedAxiom>&apos;DNA-N1-methyladenine dioxygenase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043759</classIRI>
<classLabel>methylbutanoate-CoA ligase activity</classLabel>
<deletedAxiom>&apos;methylbutanoate-CoA ligase activity&apos; SubClassOf &apos;medium-chain fatty acid-CoA ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;methylbutanoate-CoA ligase activity&apos; SubClassOf &apos;short-chain fatty acid-CoA ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102574</classIRI>
<classLabel>3-oxo-myristoyl-ACP hydrolase activity</classLabel>
<deletedAxiom>&apos;3-oxo-myristoyl-ACP hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102575</classIRI>
<classLabel>3-oxo-dodecanoyl-ACP hydrolase activity</classLabel>
<deletedAxiom>&apos;3-oxo-dodecanoyl-ACP hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102576</classIRI>
<classLabel>3-oxo-palmitoyl-ACP hydrolase activity</classLabel>
<deletedAxiom>&apos;3-oxo-palmitoyl-ACP hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901530</classIRI>
<classLabel>response to hypochlorite</classLabel>
<deletedAxiom>&apos;response to hypochlorite&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901585</classIRI>
<classLabel>regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;acid-sensing ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;acid-sensing ion channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of monoatomic ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901586</classIRI>
<classLabel>negative regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;acid-sensing ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;acid-sensing ion channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of acid-sensing ion channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901587</classIRI>
<classLabel>positive regulation of acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;acid-sensing ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;acid-sensing ion channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of acid-sensing ion channel activity&apos; SubClassOf &apos;regulation of acid-sensing ion channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901562</classIRI>
<classLabel>response to paraquat</classLabel>
<deletedAxiom>&apos;response to paraquat&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018657</classIRI>
<classLabel>toluene 3-monooxygenase activity</classLabel>
<deletedAxiom>&apos;toluene 3-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043682</classIRI>
<classLabel>P-type divalent copper transporter activity</classLabel>
<deletedAxiom>&apos;P-type divalent copper transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;P-type divalent copper transporter activity&apos; SubClassOf &apos;sulfur compound transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901605</classIRI>
<classLabel>alpha-amino acid metabolic process</classLabel>
<newAxiom>&apos;alpha-amino acid metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;alpha-amino acid metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901607</classIRI>
<classLabel>alpha-amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;alpha-amino acid biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;alpha-amino acid biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;alpha-amino acid biosynthetic process&apos; SubClassOf &apos;carboxylic acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006604</classIRI>
<classLabel>phosphoarginine metabolic process</classLabel>
<deletedAxiom>&apos;phosphoarginine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phosphoarginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;phosphoarginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006623</classIRI>
<classLabel>protein targeting to vacuole</classLabel>
<newAxiom>&apos;protein targeting to vacuole&apos; SubClassOf &apos;vacuolar transport&apos;</newAxiom>
<newAxiom>&apos;protein targeting to vacuole&apos; SubClassOf &apos;intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006622</classIRI>
<classLabel>protein targeting to lysosome</classLabel>
<newAxiom>&apos;protein targeting to lysosome&apos; SubClassOf &apos;lysosomal transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006520</classIRI>
<classLabel>amino acid metabolic process</classLabel>
<deletedAxiom>&apos;amino acid metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;amino acid metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;amino acid metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006522</classIRI>
<classLabel>alanine metabolic process</classLabel>
<deletedAxiom>&apos;alanine metabolic process&apos; SubClassOf &apos;pyruvate family amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;alanine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006524</classIRI>
<classLabel>alanine catabolic process</classLabel>
<deletedAxiom>&apos;alanine catabolic process&apos; SubClassOf &apos;pyruvate family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;alanine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;alanine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006523</classIRI>
<classLabel>alanine biosynthetic process</classLabel>
<deletedAxiom>&apos;alanine biosynthetic process&apos; SubClassOf &apos;pyruvate family amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;alanine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;alanine biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006525</classIRI>
<classLabel>arginine metabolic process</classLabel>
<deletedAxiom>&apos;arginine metabolic process&apos; SubClassOf &apos;glutamine family amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;arginine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006534</classIRI>
<classLabel>cysteine metabolic process</classLabel>
<deletedAxiom>&apos;cysteine metabolic process&apos; SubClassOf &apos;serine family amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cysteine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006537</classIRI>
<classLabel>glutamate biosynthetic process</classLabel>
<deletedAxiom>&apos;glutamate biosynthetic process&apos; SubClassOf &apos;amide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006536</classIRI>
<classLabel>glutamate metabolic process</classLabel>
<deletedAxiom>&apos;glutamate metabolic process&apos; SubClassOf &apos;amide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006547</classIRI>
<classLabel>histidine metabolic process</classLabel>
<deletedAxiom>&apos;histidine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;histidine metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;histidine metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006553</classIRI>
<classLabel>lysine metabolic process</classLabel>
<deletedAxiom>&apos;lysine metabolic process&apos; SubClassOf &apos;aspartate family amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;lysine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006554</classIRI>
<classLabel>lysine catabolic process</classLabel>
<deletedAxiom>&apos;lysine catabolic process&apos; SubClassOf &apos;aspartate family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;lysine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;lysine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006581</classIRI>
<classLabel>acetylcholine catabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102393</classIRI>
<classLabel>decanoyl-[acp] 2-dehydrogenase activity</classLabel>
<deletedAxiom>&apos;decanoyl-[acp] 2-dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006591</classIRI>
<classLabel>ornithine metabolic process</classLabel>
<newAxiom>&apos;ornithine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006593</classIRI>
<classLabel>ornithine catabolic process</classLabel>
<newAxiom>&apos;ornithine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006592</classIRI>
<classLabel>ornithine biosynthetic process</classLabel>
<newAxiom>&apos;ornithine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;ornithine biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031533</classIRI>
<classLabel>mRNA cap methyltransferase complex</classLabel>
<deletedAxiom>&apos;mRNA cap methyltransferase complex&apos; SubClassOf &apos;methyltransferase complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043491</classIRI>
<classLabel>phosphatidylinositol 3-kinase/protein kinase B signal transduction</classLabel>
<deletedAxiom>&apos;phosphatidylinositol 3-kinase/protein kinase B signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;phosphatidylinositol 3-kinase/protein kinase B signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102327</classIRI>
<classLabel>3-oxoacyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;3-oxoacyl-CoA hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901710</classIRI>
<classLabel>regulation of homoserine biosynthetic process</classLabel>
<newAxiom>&apos;regulation of homoserine biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901711</classIRI>
<classLabel>negative regulation of homoserine biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of homoserine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901712</classIRI>
<classLabel>positive regulation of homoserine biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of homoserine biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901716</classIRI>
<classLabel>negative regulation of gamma-aminobutyric acid catabolic process</classLabel>
<newAxiom>&apos;negative regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901717</classIRI>
<classLabel>positive regulation of gamma-aminobutyric acid catabolic process</classLabel>
<newAxiom>&apos;positive regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901725</classIRI>
<classLabel>regulation of histone deacetylase activity</classLabel>
<deletedAxiom>&apos;regulation of histone deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deacetylase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylase activity&apos; SubClassOf &apos;regulation of histone deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylase activity&apos; SubClassOf &apos;regulation of deacetylase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901726</classIRI>
<classLabel>negative regulation of histone deacetylase activity</classLabel>
<deletedAxiom>&apos;negative regulation of histone deacetylase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deacetylase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylase activity&apos; SubClassOf &apos;negative regulation of deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylase activity&apos; SubClassOf &apos;negative regulation of histone deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylase activity&apos; SubClassOf &apos;regulation of histone deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deacetylase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901727</classIRI>
<classLabel>positive regulation of histone deacetylase activity</classLabel>
<deletedAxiom>&apos;positive regulation of histone deacetylase activity&apos; SubClassOf &apos;positive regulation of deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylase activity&apos; SubClassOf &apos;regulation of histone deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deacetylase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deacetylase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylase activity&apos; SubClassOf &apos;positive regulation of histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006407</classIRI>
<classLabel>rRNA export from nucleus</classLabel>
<deletedAxiom>&apos;rRNA export from nucleus&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ribosome biogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;rRNA export from nucleus&apos; SubClassOf &apos;ncRNA export from nucleus&apos;</deletedAxiom>
<deletedAxiom>&apos;rRNA export from nucleus&apos; SubClassOf &apos;rRNA transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018400</classIRI>
<classLabel>peptidyl-proline hydroxylation to 3-hydroxy-L-proline</classLabel>
<deletedAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;peptidyl-proline hydroxylation to 3-hydroxy-L-proline&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018401</classIRI>
<classLabel>peptidyl-proline hydroxylation to 4-hydroxy-L-proline</classLabel>
<newAxiom>&apos;peptidyl-proline hydroxylation to 4-hydroxy-L-proline&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031427</classIRI>
<classLabel>response to methotrexate</classLabel>
<deletedAxiom>&apos;response to methotrexate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102278</classIRI>
<classLabel>N,N&apos;-diacetylchitobiose synthase activity</classLabel>
<deletedAxiom>&apos;N,N&apos;-diacetylchitobiose synthase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043430</classIRI>
<classLabel>2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043428</classIRI>
<classLabel>2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043429</classIRI>
<classLabel>2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043418</classIRI>
<classLabel>homocysteine catabolic process</classLabel>
<newAxiom>&apos;homocysteine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031458</classIRI>
<classLabel>ABC-type betaine transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type betaine transporter activity&apos; SubClassOf &apos;ABC-type quaternary ammonium compound transporting activity&apos;</deletedAxiom>
<newAxiom>&apos;ABC-type betaine transporter activity&apos; SubClassOf &apos;ABC-type transporter activity&apos;</newAxiom>
<newAxiom>&apos;ABC-type betaine transporter activity&apos; SubClassOf &apos;organic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102190</classIRI>
<classLabel>4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102184</classIRI>
<classLabel>cycloartenol 4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;cycloartenol 4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102185</classIRI>
<classLabel>4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102186</classIRI>
<classLabel>4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102188</classIRI>
<classLabel>4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033913</classIRI>
<classLabel>glucan endo-1,2-beta-glucosidase activity</classLabel>
<deletedAxiom>&apos;glucan endo-1,2-beta-glucosidase activity&apos; SubClassOf &apos;beta-glucosidase activity&apos;</deletedAxiom>
<newAxiom>&apos;glucan endo-1,2-beta-glucosidase activity&apos; SubClassOf &apos;glucosidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018313</classIRI>
<classLabel>peptide cross-linking via L-alanyl-5-imidazolinone glycine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-alanyl-5-imidazolinone glycine&apos; SubClassOf &apos;peptidyl-alanine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-alanyl-5-imidazolinone glycine&apos; SubClassOf &apos;peptide cross-linking via 5-imidazolinone glycine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102150</classIRI>
<classLabel>3-oxo-myristoyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;3-oxo-myristoyl-CoA hydrolase activity&apos; SubClassOf &apos;thiolester hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070909</classIRI>
<classLabel>glutamate:gamma-aminobutyric acid antiporter activity</classLabel>
<deletedAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate:gamma-aminobutyric acid antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043333</classIRI>
<classLabel>2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity</classLabel>
<deletedAxiom>&apos;2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity&apos; SubClassOf &apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043334</classIRI>
<classLabel>2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018396</classIRI>
<classLabel>peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine</classLabel>
<deletedAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070932</classIRI>
<classLabel>histone H3 deacetylation</classLabel>
<deletedAxiom>&apos;histone H3 deacetylation&apos; SubClassOf &apos;histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070933</classIRI>
<classLabel>histone H4 deacetylation</classLabel>
<deletedAxiom>&apos;histone H4 deacetylation&apos; SubClassOf &apos;histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043278</classIRI>
<classLabel>response to morphine</classLabel>
<deletedAxiom>&apos;response to morphine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031291</classIRI>
<classLabel>Ran protein signal transduction</classLabel>
<deletedAxiom>&apos;Ran protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Ran protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043295</classIRI>
<classLabel>glutathione binding</classLabel>
<newAxiom>&apos;glutathione binding&apos; SubClassOf &apos;modified amino acid binding&apos;</newAxiom>
<newAxiom>&apos;glutathione binding&apos; SubClassOf &apos;oligopeptide binding&apos;</newAxiom>
<newAxiom>&apos;glutathione binding&apos; SubClassOf &apos;sulfur compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901974</classIRI>
<classLabel>glycerate transmembrane transporter activity</classLabel>
<newAxiom>&apos;glycerate transmembrane transporter activity&apos; SubClassOf &apos;carbohydrate transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;glycerate transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901975</classIRI>
<classLabel>glycerate transmembrane transport</classLabel>
<newAxiom>&apos;glycerate transmembrane transport&apos; SubClassOf &apos;carbohydrate transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043287</classIRI>
<classLabel>poly(3-hydroxyalkanoate) binding</classLabel>
<deletedAxiom>&apos;poly(3-hydroxyalkanoate) binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;poly(3-hydroxyalkanoate) binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901997</classIRI>
<classLabel>negative regulation of indoleacetic acid biosynthetic process via tryptophan</classLabel>
<newAxiom>&apos;negative regulation of indoleacetic acid biosynthetic process via tryptophan&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021808</classIRI>
<classLabel>cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration</classLabel>
<deletedAxiom>&apos;cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;initiation of movement involved in cerebral cortex radial glia guided migration&apos;</deletedAxiom>
<deletedAxiom>&apos;cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration&apos; SubClassOf &apos;calcium-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102030</classIRI>
<classLabel>dTDP-L-rhamnose synthetase activity</classLabel>
<deletedAxiom>&apos;dTDP-L-rhamnose synthetase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102035</classIRI>
<classLabel>isobutyryl-CoA:FAD oxidoreductase activity</classLabel>
<deletedAxiom>&apos;isobutyryl-CoA:FAD oxidoreductase activity&apos; SubClassOf &apos;acyl-CoA dehydrogenase activity&apos;</deletedAxiom>
<newAxiom>&apos;isobutyryl-CoA:FAD oxidoreductase activity&apos; SubClassOf &apos;short-chain-acyl-CoA dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102025</classIRI>
<classLabel>ABC-type thiosulfate transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type thiosulfate transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045815</classIRI>
<classLabel>transcription initiation-coupled chromatin remodeling</classLabel>
<deletedAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf &apos;chromatin remodeling&apos;</deletedAxiom>
<newAxiom>&apos;transcription initiation-coupled chromatin remodeling&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141137</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021880</classIRI>
<classLabel>Notch signaling pathway involved in forebrain neuron fate commitment</classLabel>
<deletedAxiom>&apos;Notch signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;commitment of multipotent stem cells to neuronal lineage in forebrain&apos;</deletedAxiom>
<deletedAxiom>&apos;Notch signaling pathway involved in forebrain neuron fate commitment&apos; EquivalentTo &apos;Notch signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;forebrain neuron fate commitment&apos;)</deletedAxiom>
<deletedAxiom>&apos;Notch signaling pathway involved in forebrain neuron fate commitment&apos; SubClassOf &apos;Notch signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102053</classIRI>
<classLabel>(-)-jasmonoyl-isoleucine synthetase activity</classLabel>
<deletedAxiom>&apos;(-)-jasmonoyl-isoleucine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018232</classIRI>
<classLabel>peptide cross-linking via S-(L-isoglutamyl)-L-cysteine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via S-(L-isoglutamyl)-L-cysteine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(L-isoglutamyl)-L-cysteine&apos; SubClassOf &apos;peptidyl-glutamine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(L-isoglutamyl)-L-cysteine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018233</classIRI>
<classLabel>peptide cross-linking via 2&apos;-(S-L-cysteinyl)-L-histidine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 2&apos;-(S-L-cysteinyl)-L-histidine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 2&apos;-(S-L-cysteinyl)-L-histidine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 2&apos;-(S-L-cysteinyl)-L-histidine&apos; SubClassOf &apos;peptidyl-histidine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018234</classIRI>
<classLabel>peptide cross-linking via 3&apos;-(S-L-cysteinyl)-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(S-L-cysteinyl)-L-tyrosine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(S-L-cysteinyl)-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(S-L-cysteinyl)-L-tyrosine&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102057</classIRI>
<classLabel>jasmonoyl-valine synthetase activity</classLabel>
<deletedAxiom>&apos;jasmonoyl-valine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102058</classIRI>
<classLabel>jasmonoyl-leucine synthetase activity</classLabel>
<deletedAxiom>&apos;jasmonoyl-leucine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031210</classIRI>
<classLabel>phosphatidylcholine binding</classLabel>
<newAxiom>&apos;phosphatidylcholine binding&apos; SubClassOf &apos;quaternary ammonium group binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102040</classIRI>
<classLabel>fumarate reductase (menaquinone)</classLabel>
<deletedAxiom>&apos;fumarate reductase (menaquinone)&apos; SubClassOf &apos;succinate dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033857</classIRI>
<classLabel>diphosphoinositol-pentakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;diphosphoinositol-pentakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;diphosphoinositol-pentakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018253</classIRI>
<classLabel>peptide cross-linking via 5-imidazolinone glycine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 5-imidazolinone glycine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 5-imidazolinone glycine&apos; SubClassOf &apos;peptidyl-glycine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901905</classIRI>
<classLabel>response to tamsulosin</classLabel>
<deletedAxiom>&apos;response to tamsulosin&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018274</classIRI>
<classLabel>peptide cross-linking via L-lysinoalanine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-lysinoalanine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-lysinoalanine&apos; SubClassOf &apos;peptidyl-lysine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-lysinoalanine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102006</classIRI>
<classLabel>4-methyl-2-oxopentanoate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;4-methyl-2-oxopentanoate dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070734</classIRI>
<classLabel>histone H3-K27 methylation</classLabel>
<deletedAxiom>&apos;histone H3-K27 methylation&apos; SubClassOf &apos;histone lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043167</classIRI>
<classLabel>ion binding</classLabel>
<deletedAxiom>&apos;ion binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;ion binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080185</classIRI>
<classLabel>effector-mediated activation of plant hypersensitive response by symbiont</classLabel>
<deletedAxiom>&apos;effector-mediated activation of plant hypersensitive response by symbiont&apos; SubClassOf &apos;symbiont-mediated perturbation of host defense-related programmed cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;effector-mediated activation of plant hypersensitive response by symbiont&apos; SubClassOf &apos;induction by symbiont of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080182</classIRI>
<classLabel>histone H3-K4 trimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 trimethylation&apos; SubClassOf &apos;histone H3-K4 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K4 trimethylation&apos; SubClassOf &apos;peptidyl-lysine trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080170</classIRI>
<classLabel>hydrogen peroxide transmembrane transport</classLabel>
<deletedAxiom>&apos;hydrogen peroxide transmembrane transport&apos; SubClassOf &apos;organic substance transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006101</classIRI>
<classLabel>citrate metabolic process</classLabel>
<deletedAxiom>&apos;citrate metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018124</classIRI>
<classLabel>peptide cross-linking via 5&apos;-(N6-L-lysine)-L-topaquinone</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 5&apos;-(N6-L-lysine)-L-topaquinone&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 5&apos;-(N6-L-lysine)-L-topaquinone&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 5&apos;-(N6-L-lysine)-L-topaquinone&apos; SubClassOf &apos;peptidyl-lysine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018132</classIRI>
<classLabel>peptide cross-linking via L-cysteine oxazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018133</classIRI>
<classLabel>peptide cross-linking via L-cysteine oxazolinecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolinecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolinecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine oxazolinecarboxylic acid&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018134</classIRI>
<classLabel>peptide cross-linking via glycine oxazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via glycine oxazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via glycine oxazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-glycine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via glycine oxazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045754</classIRI>
<classLabel>positive regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetate catabolic process&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045753</classIRI>
<classLabel>negative regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetate catabolic process&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018137</classIRI>
<classLabel>peptide cross-linking via glycine thiazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via glycine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via glycine thiazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via glycine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-glycine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018138</classIRI>
<classLabel>peptide cross-linking via L-serine thiazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-serine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-serine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-serine thiazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018139</classIRI>
<classLabel>peptide cross-linking via L-phenylalanine thiazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-phenylalanine thiazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-phenylalanine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-phenylalanine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-phenylalanine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018140</classIRI>
<classLabel>peptide cross-linking via L-cysteine thiazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteine thiazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018141</classIRI>
<classLabel>peptide cross-linking via L-lysine thiazolecarboxylic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-lysine thiazolecarboxylic acid&apos; SubClassOf &apos;peptide cross-linking via an oxazole or thiazole&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-lysine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-lysine thiazolecarboxylic acid&apos; SubClassOf &apos;peptidyl-lysine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018142</classIRI>
<classLabel>protein-DNA covalent cross-linking</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking&apos; SubClassOf &apos;nucleic acid-protein covalent cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018145</classIRI>
<classLabel>protein-DNA covalent cross-linking via peptidyl-serine</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-serine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-serine&apos; SubClassOf &apos;protein-DNA covalent cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045734</classIRI>
<classLabel>regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;regulation of acetate catabolic process&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018151</classIRI>
<classLabel>peptide cross-linking via L-histidyl-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-histidyl-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-histidyl-L-tyrosine&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-histidyl-L-tyrosine&apos; SubClassOf &apos;peptidyl-histidine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018152</classIRI>
<classLabel>peptide cross-linking via 3&apos;-(1&apos;-L-histidyl)-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(1&apos;-L-histidyl)-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking via L-histidyl-L-tyrosine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018154</classIRI>
<classLabel>peptide cross-linking via (2R,6R)-lanthionine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via (2R,6R)-lanthionine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2R,6R)-lanthionine&apos; SubClassOf &apos;peptide cross-linking via lanthionine or 3-methyl-lanthionine&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2R,6R)-lanthionine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018155</classIRI>
<classLabel>peptide cross-linking via sn-(2S,6R)-lanthionine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via sn-(2S,6R)-lanthionine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via sn-(2S,6R)-lanthionine&apos; SubClassOf &apos;peptide cross-linking via lanthionine or 3-methyl-lanthionine&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via sn-(2S,6R)-lanthionine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018156</classIRI>
<classLabel>peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine&apos; SubClassOf &apos;peptidyl-threonine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018157</classIRI>
<classLabel>peptide cross-linking via an oxazole or thiazole</classLabel>
<deletedAxiom>&apos;peptide cross-linking via an oxazole or thiazole&apos; SubClassOf &apos;oxazole or thiazole biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via an oxazole or thiazole&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031126</classIRI>
<classLabel>sno(s)RNA 3&apos;-end processing</classLabel>
<deletedAxiom>&apos;sno(s)RNA 3&apos;-end processing&apos; SubClassOf &apos;regulatory ncRNA 3&apos;-end processing&apos;</deletedAxiom>
<newAxiom>&apos;sno(s)RNA 3&apos;-end processing&apos; SubClassOf &apos;RNA 3&apos;-end processing&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018150</classIRI>
<classLabel>peptide cross-linking via 3-(3&apos;-L-histidyl)-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3-(3&apos;-L-histidyl)-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking via L-histidyl-L-tyrosine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018162</classIRI>
<classLabel>peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine&apos; SubClassOf &apos;peptidyl-threonine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018163</classIRI>
<classLabel>protein-DNA covalent cross-linking via the 5&apos;-end to peptidyl-tyrosine</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via the 5&apos;-end to peptidyl-tyrosine&apos; SubClassOf &apos;protein-DNA covalent cross-linking via peptidyl-tyrosine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018164</classIRI>
<classLabel>protein-DNA covalent cross-linking via peptidyl-threonine</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-threonine&apos; SubClassOf &apos;protein-DNA covalent cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-threonine&apos; SubClassOf &apos;peptidyl-threonine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045763</classIRI>
<classLabel>negative regulation of cellular amino acid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045764</classIRI>
<classLabel>positive regulation of amino acid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of amino acid metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of amino acid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031029</classIRI>
<classLabel>regulation of septation initiation signaling</classLabel>
<deletedAxiom>&apos;regulation of septation initiation signaling&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of septation initiation signaling&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031028</classIRI>
<classLabel>septation initiation signaling</classLabel>
<deletedAxiom>&apos;septation initiation signaling&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;septation initiation signaling&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031030</classIRI>
<classLabel>negative regulation of septation initiation signaling</classLabel>
<deletedAxiom>&apos;negative regulation of septation initiation signaling&apos; SubClassOf &apos;negative regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of septation initiation signaling&apos; SubClassOf &apos;negative regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031031</classIRI>
<classLabel>positive regulation of septation initiation signaling</classLabel>
<deletedAxiom>&apos;positive regulation of septation initiation signaling&apos; SubClassOf &apos;positive regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of septation initiation signaling&apos; SubClassOf &apos;positive regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018064</classIRI>
<classLabel>protein-L-histidine N-tele-methyltransferase activity</classLabel>
<newAxiom>&apos;protein-L-histidine N-tele-methyltransferase activity&apos; SubClassOf &apos;protein methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018069</classIRI>
<classLabel>peptide cross-linking via 4&apos;-(L-tryptophan)-L-tryptophyl quinone</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 4&apos;-(L-tryptophan)-L-tryptophyl quinone&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 4&apos;-(L-tryptophan)-L-tryptophyl quinone&apos; SubClassOf &apos;peptidyl-tryptophan modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006083</classIRI>
<classLabel>acetate metabolic process</classLabel>
<deletedAxiom>&apos;acetate metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031056</classIRI>
<classLabel>regulation of histone modification</classLabel>
<deletedAxiom>&apos;regulation of histone modification&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone modification&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone modification&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone modification&apos; SubClassOf &apos;regulation of post-translational protein modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018081</classIRI>
<classLabel>peptide cross-linking via lanthionine or 3-methyl-lanthionine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via lanthionine or 3-methyl-lanthionine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018096</classIRI>
<classLabel>peptide cross-linking via S-(2-aminovinyl)-D-cysteine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-D-cysteine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-D-cysteine&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-(2-aminovinyl)-D-cysteine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031063</classIRI>
<classLabel>regulation of histone deacetylation</classLabel>
<deletedAxiom>&apos;regulation of histone deacetylation&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylation&apos; SubClassOf &apos;regulation of protein deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deacetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone deacetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031062</classIRI>
<classLabel>positive regulation of histone methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone methylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone methylation&apos; SubClassOf &apos;regulation of histone methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031065</classIRI>
<classLabel>positive regulation of histone deacetylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone deacetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylation&apos; SubClassOf &apos;regulation of histone deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone deacetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone deacetylation&apos; SubClassOf &apos;positive regulation of protein deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031064</classIRI>
<classLabel>negative regulation of histone deacetylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone deacetylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deacetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylation&apos; SubClassOf &apos;regulation of histone deacetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone deacetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031061</classIRI>
<classLabel>negative regulation of histone methylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone methylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone methylation&apos; SubClassOf &apos;regulation of histone methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031060</classIRI>
<classLabel>regulation of histone methylation</classLabel>
<deletedAxiom>&apos;regulation of histone methylation&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone methylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone methylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone methylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080021</classIRI>
<classLabel>response to benzoic acid</classLabel>
<deletedAxiom>&apos;response to benzoic acid&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033609</classIRI>
<classLabel>oxalate metabolic process</classLabel>
<deletedAxiom>&apos;oxalate metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008652</classIRI>
<classLabel>amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;amino acid biosynthetic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008659</classIRI>
<classLabel>(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity</classLabel>
<deletedAxiom>&apos;(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
<newAxiom>&apos;(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity&apos; SubClassOf &apos;(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008689</classIRI>
<classLabel>3-demethylubiquinone-9 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinone-9 3-O-methyltransferase activity&apos; SubClassOf &apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033643</classIRI>
<classLabel>host cell part</classLabel>
<deletedAxiom>&apos;host cell part&apos; EquivalentTo &apos;host cellular component&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;host cell&apos;)</deletedAxiom>
<deletedAxiom>&apos;host cell part&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;host cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070512</classIRI>
<classLabel>positive regulation of histone H4-K20 methylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H4-K20 methylation&apos; SubClassOf &apos;positive regulation of histone methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033591</classIRI>
<classLabel>response to L-ascorbic acid</classLabel>
<deletedAxiom>&apos;response to L-ascorbic acid&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070543</classIRI>
<classLabel>response to linoleic acid</classLabel>
<deletedAxiom>&apos;response to linoleic acid&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070544</classIRI>
<classLabel>histone H3-K36 demethylation</classLabel>
<deletedAxiom>&apos;histone H3-K36 demethylation&apos; SubClassOf &apos;histone lysine demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070535</classIRI>
<classLabel>histone H2A K63-linked ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;protein K63-linked ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A K63-linked ubiquitination&apos; SubClassOf &apos;histone H2A ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070537</classIRI>
<classLabel>histone H2A K63-linked deubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A K63-linked deubiquitination&apos; SubClassOf &apos;histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A K63-linked deubiquitination&apos; SubClassOf &apos;protein K63-linked deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900992</classIRI>
<classLabel>(-)-secologanin metabolic process</classLabel>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;olefinic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;organic cyclic compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;beta-glucoside metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;monoterpenoid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;heterocycle metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin metabolic process&apos; SubClassOf &apos;cellular aldehyde metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900993</classIRI>
<classLabel>(-)-secologanin catabolic process</classLabel>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;heterocycle catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;monoterpenoid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;organic cyclic compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;aldehyde catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;beta-glucoside catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;(-)-secologanin metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;(-)-secologanin catabolic process&apos; SubClassOf &apos;olefinic compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900994</classIRI>
<classLabel>(-)-secologanin biosynthetic process</classLabel>
<deletedAxiom>&apos;(-)-secologanin biosynthetic process&apos; SubClassOf &apos;(-)-secologanin metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033507</classIRI>
<classLabel>glucosinolate biosynthetic process from phenylalanine</classLabel>
<deletedAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glucosinolate biosynthetic process from phenylalanine&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033523</classIRI>
<classLabel>histone H2B ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2B ubiquitination&apos; SubClassOf &apos;histone ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033522</classIRI>
<classLabel>histone H2A ubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A ubiquitination&apos; SubClassOf &apos;histone ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070431</classIRI>
<classLabel>nucleotide-binding oligomerization domain containing 2 signaling pathway</classLabel>
<deletedAxiom>&apos;nucleotide-binding oligomerization domain containing 2 signaling pathway&apos; SubClassOf &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide-binding oligomerization domain containing 2 signaling pathway&apos; SubClassOf &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070423</classIRI>
<classLabel>nucleotide-binding oligomerization domain containing signaling pathway</classLabel>
<deletedAxiom>&apos;nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf &apos;cytoplasmic pattern recognition receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070424</classIRI>
<classLabel>regulation of nucleotide-binding oligomerization domain containing signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;)</deletedAxiom>
<newAxiom>&apos;regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;)</newAxiom>
<newAxiom>&apos;regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070425</classIRI>
<classLabel>negative regulation of nucleotide-binding oligomerization domain containing signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;)</newAxiom>
<newAxiom>&apos;negative regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070426</classIRI>
<classLabel>positive regulation of nucleotide-binding oligomerization domain containing signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</newAxiom>
<newAxiom>&apos;positive regulation of nucleotide-binding oligomerization domain containing signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070427</classIRI>
<classLabel>nucleotide-binding oligomerization domain containing 1 signaling pathway</classLabel>
<deletedAxiom>&apos;nucleotide-binding oligomerization domain containing 1 signaling pathway&apos; SubClassOf &apos;nucleotide-binding oligomerization domain containing signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide-binding oligomerization domain containing 1 signaling pathway&apos; SubClassOf &apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033487</classIRI>
<classLabel>pelargonidin 3-O-glucoside biosynthetic process</classLabel>
<deletedAxiom>&apos;pelargonidin 3-O-glucoside biosynthetic process&apos; SubClassOf &apos;anthocyanin-containing compound biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;pelargonidin 3-O-glucoside biosynthetic process&apos; SubClassOf &apos;flavonoid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008425</classIRI>
<classLabel>2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;quinone cofactor methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf &apos;C-methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ubiquinone biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008430</classIRI>
<classLabel>selenium binding</classLabel>
<deletedAxiom>&apos;selenium binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;selenium binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008470</classIRI>
<classLabel>isovaleryl-CoA dehydrogenase activity</classLabel>
<deletedAxiom>&apos;isovaleryl-CoA dehydrogenase activity&apos; SubClassOf &apos;acyl-CoA dehydrogenase activity&apos;</deletedAxiom>
<newAxiom>&apos;isovaleryl-CoA dehydrogenase activity&apos; SubClassOf &apos;short-chain-acyl-CoA dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045301</classIRI>
<classLabel>tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity</classLabel>
<deletedAxiom>&apos;tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033321</classIRI>
<classLabel>homomethionine metabolic process</classLabel>
<deletedAxiom>&apos;homomethionine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;homomethionine metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
<newAxiom>&apos;homomethionine metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045326</classIRI>
<classLabel>protein-DNA covalent cross-linking via the 3&apos;-end to peptidyl-tyrosine</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via the 3&apos;-end to peptidyl-tyrosine&apos; SubClassOf &apos;protein-DNA covalent cross-linking via peptidyl-tyrosine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045327</classIRI>
<classLabel>protein-DNA covalent cross-linking via peptidyl-tyrosine</classLabel>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-tyrosine&apos; SubClassOf &apos;protein-DNA covalent cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;protein-DNA covalent cross-linking via peptidyl-tyrosine&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035998</classIRI>
<classLabel>7,8-dihydroneopterin 3&apos;-triphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;7,8-dihydroneopterin 3&apos;-triphosphate biosynthetic process&apos; SubClassOf &apos;dihydrobiopterin metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;7,8-dihydroneopterin 3&apos;-triphosphate biosynthetic process&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;7,8-dihydroneopterin 3&apos;-triphosphate biosynthetic process&apos; SubClassOf &apos;organophosphate biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;7,8-dihydroneopterin 3&apos;-triphosphate biosynthetic process&apos; SubClassOf &apos;pteridine-containing compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070360</classIRI>
<classLabel>actin polymerization-dependent cell migration in host</classLabel>
<deletedAxiom>&apos;actin polymerization-dependent cell migration in host&apos; SubClassOf &apos;migration in host&apos;</deletedAxiom>
<newAxiom>&apos;actin polymerization-dependent cell migration in host&apos; SubClassOf &apos;cell-to-cell migration in host&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141105</classIRI>
<classLabel>symbiont-mediated suppression of host toll-like receptor signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host toll-like receptor signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141104</classIRI>
<classLabel>symbiont-mediated activation of host G protein-coupled receptor signal transduction</classLabel>
<newAxiom>&apos;symbiont-mediated activation of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;symbiont-mediated activation of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035927</classIRI>
<classLabel>RNA import into mitochondrion</classLabel>
<deletedAxiom>&apos;RNA import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;RNA import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047901</classIRI>
<classLabel>formyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;formyl-CoA hydrolase activity&apos; SubClassOf &apos;CoA hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047904</classIRI>
<classLabel>fructose 5-dehydrogenase activity</classLabel>
<deletedAxiom>&apos;fructose 5-dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on CH-OH group of donors&apos;</deletedAxiom>
<newAxiom>&apos;fructose 5-dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060919</classIRI>
<classLabel>auxin import into cell</classLabel>
<deletedAxiom>&apos;auxin import into cell&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035975</classIRI>
<classLabel>carbamoyl phosphate catabolic process</classLabel>
<deletedAxiom>&apos;carbamoyl phosphate catabolic process&apos; SubClassOf &apos;carbamoyl phosphate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;carbamoyl phosphate catabolic process&apos; SubClassOf &apos;organophosphate catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;carbamoyl phosphate catabolic process&apos; SubClassOf &apos;cellular nitrogen compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035872</classIRI>
<classLabel>nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway</classLabel>
<deletedAxiom>&apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos; SubClassOf &apos;intracellular receptor signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway&apos; SubClassOf &apos;cytoplasmic pattern recognition receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060823</classIRI>
<classLabel>canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation</classLabel>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neural plate anterior/posterior regionalization&apos;</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; EquivalentTo &apos;canonical Wnt signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;neural plate anterior/posterior regionalization&apos;)</deletedAxiom>
<deletedAxiom>&apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;canonical Wnt signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060829</classIRI>
<classLabel>negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation</classLabel>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;negative regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060827</classIRI>
<classLabel>regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation</classLabel>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;regulation of anatomical structure morphogenesis&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;regulation of embryonic development&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf &apos;regulation of canonical Wnt signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035864</classIRI>
<classLabel>response to potassium ion</classLabel>
<deletedAxiom>&apos;response to potassium ion&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to potassium ion&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035865</classIRI>
<classLabel>cellular response to potassium ion</classLabel>
<deletedAxiom>&apos;cellular response to potassium ion&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to potassium ion&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033226</classIRI>
<classLabel>2-aminoethylphosphonate binding</classLabel>
<deletedAxiom>&apos;2-aminoethylphosphonate binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;2-aminoethylphosphonate binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008272</classIRI>
<classLabel>sulfate transport</classLabel>
<deletedAxiom>&apos;sulfate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035891</classIRI>
<classLabel>exit from host cell</classLabel>
<deletedAxiom>&apos;exit from host cell&apos; SubClassOf &apos;movement in host&apos;</deletedAxiom>
<newAxiom>&apos;exit from host cell&apos; SubClassOf &apos;biological process involved in interaction with host&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008292</classIRI>
<classLabel>acetylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;acetylcholine biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008291</classIRI>
<classLabel>acetylcholine metabolic process</classLabel>
<deletedAxiom>&apos;acetylcholine metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045251</classIRI>
<classLabel>electron transfer flavoprotein complex</classLabel>
<deletedAxiom>&apos;electron transfer flavoprotein complex&apos; SubClassOf &apos;oxidoreductase complex&apos;</deletedAxiom>
<newAxiom>&apos;electron transfer flavoprotein complex&apos; SubClassOf &apos;protein-containing complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033274</classIRI>
<classLabel>response to vitamin B2</classLabel>
<deletedAxiom>&apos;response to vitamin B2&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033266</classIRI>
<classLabel>ABC-type choline transporter activity</classLabel>
<deletedAxiom>&apos;ABC-type choline transporter activity&apos; SubClassOf &apos;ABC-type quaternary ammonium compound transporting activity&apos;</deletedAxiom>
<newAxiom>&apos;ABC-type choline transporter activity&apos; SubClassOf &apos;ABC-type transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141076</classIRI>
<classLabel>symbiont-mediated suppression of host TRAF-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host TRAF-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141075</classIRI>
<classLabel>symbiont-mediated suppression of host JAK-STAT cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host JAK-STAT cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141077</classIRI>
<classLabel>suppression of host interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression of host interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of host interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression of host interferon-mediated signaling pathway&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;interferon-mediated signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141070</classIRI>
<classLabel>symbiont-mediated suppression of host MAPK signal transduction pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host MAPK signal transduction pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070209</classIRI>
<classLabel>ASTRA complex</classLabel>
<deletedAxiom>&apos;ASTRA complex&apos; SubClassOf &apos;nuclear protein-containing complex&apos;</deletedAxiom>
<deletedAxiom>&apos;ASTRA complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;chromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070189</classIRI>
<classLabel>kynurenine metabolic process</classLabel>
<newAxiom>&apos;kynurenine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070178</classIRI>
<classLabel>D-serine metabolic process</classLabel>
<deletedAxiom>&apos;D-serine metabolic process&apos; SubClassOf &apos;serine family amino acid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070179</classIRI>
<classLabel>D-serine biosynthetic process</classLabel>
<deletedAxiom>&apos;D-serine biosynthetic process&apos; SubClassOf &apos;serine family amino acid biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047720</classIRI>
<classLabel>indoleacetaldoxime dehydratase activity</classLabel>
<deletedAxiom>&apos;indoleacetaldoxime dehydratase activity&apos; SubClassOf &apos;lyase activity&apos;</deletedAxiom>
<newAxiom>&apos;indoleacetaldoxime dehydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141122</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047751</classIRI>
<classLabel>3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)</classLabel>
<newAxiom>&apos;3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)&apos; SubClassOf &apos;3-oxo-5-alpha-steroid 4-dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035756</classIRI>
<classLabel>transepithelial migration of symbiont in host</classLabel>
<deletedAxiom>&apos;transepithelial migration of symbiont in host&apos; SubClassOf &apos;migration in host&apos;</deletedAxiom>
<newAxiom>&apos;transepithelial migration of symbiont in host&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141142</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008199</classIRI>
<classLabel>ferric iron binding</classLabel>
<deletedAxiom>&apos;ferric iron binding&apos; SubClassOf &apos;sulfur compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072707</classIRI>
<classLabel>cellular response to sodium dodecyl sulfate</classLabel>
<deletedAxiom>&apos;cellular response to sodium dodecyl sulfate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072706</classIRI>
<classLabel>response to sodium dodecyl sulfate</classLabel>
<deletedAxiom>&apos;response to sodium dodecyl sulfate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070100</classIRI>
<classLabel>negative regulation of chemokine-mediated signaling pathway</classLabel>
<newAxiom>&apos;negative regulation of chemokine-mediated signaling pathway&apos; SubClassOf &apos;negative regulation of G protein-coupled receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070101</classIRI>
<classLabel>positive regulation of chemokine-mediated signaling pathway</classLabel>
<newAxiom>&apos;positive regulation of chemokine-mediated signaling pathway&apos; SubClassOf &apos;positive regulation of G protein-coupled receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033169</classIRI>
<classLabel>histone H3-K9 demethylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 demethylation&apos; SubClassOf &apos;histone lysine demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072753</classIRI>
<classLabel>cellular response to glutathione</classLabel>
<deletedAxiom>&apos;cellular response to glutathione&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to glutathione&apos; SubClassOf &apos;cellular response to peptide&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072756</classIRI>
<classLabel>cellular response to paraquat</classLabel>
<deletedAxiom>&apos;cellular response to paraquat&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033198</classIRI>
<classLabel>response to ATP</classLabel>
<deletedAxiom>&apos;response to ATP&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033182</classIRI>
<classLabel>regulation of histone ubiquitination</classLabel>
<deletedAxiom>&apos;regulation of histone ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone ubiquitination&apos; SubClassOf &apos;regulation of protein ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone ubiquitination&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone ubiquitination&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033184</classIRI>
<classLabel>positive regulation of histone ubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of histone ubiquitination&apos; SubClassOf &apos;positive regulation of protein ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone ubiquitination&apos; SubClassOf &apos;regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033183</classIRI>
<classLabel>negative regulation of histone ubiquitination</classLabel>
<deletedAxiom>&apos;negative regulation of histone ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone ubiquitination&apos; SubClassOf &apos;regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone ubiquitination&apos; SubClassOf &apos;negative regulation of protein ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone ubiquitination&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070076</classIRI>
<classLabel>histone lysine demethylation</classLabel>
<deletedAxiom>&apos;histone lysine demethylation&apos; SubClassOf &apos;histone demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070078</classIRI>
<classLabel>histone H3-R2 demethylation</classLabel>
<deletedAxiom>&apos;histone H3-R2 demethylation&apos; SubClassOf &apos;histone demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070079</classIRI>
<classLabel>histone H4-R3 demethylation</classLabel>
<deletedAxiom>&apos;histone H4-R3 demethylation&apos; SubClassOf &apos;histone demethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070098</classIRI>
<classLabel>chemokine-mediated signaling pathway</classLabel>
<newAxiom>&apos;chemokine-mediated signaling pathway&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070099</classIRI>
<classLabel>regulation of chemokine-mediated signaling pathway</classLabel>
<newAxiom>&apos;regulation of chemokine-mediated signaling pathway&apos; SubClassOf &apos;regulation of G protein-coupled receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035731</classIRI>
<classLabel>dinitrosyl-iron complex binding</classLabel>
<deletedAxiom>&apos;dinitrosyl-iron complex binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;dinitrosyl-iron complex binding&apos; SubClassOf &apos;metal cluster binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047702</classIRI>
<classLabel>beta-lysine 5,6-aminomutase activity</classLabel>
<deletedAxiom>&apos;beta-lysine 5,6-aminomutase activity&apos; SubClassOf &apos;intramolecular aminotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035616</classIRI>
<classLabel>histone H2B conserved C-terminal lysine deubiquitination</classLabel>
<deletedAxiom>&apos;histone H2B conserved C-terminal lysine deubiquitination&apos; SubClassOf &apos;histone deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035647</classIRI>
<classLabel>3-oxo-delta(4,5)-steroid 5-beta-reductase activity</classLabel>
<deletedAxiom>&apos;3-oxo-delta(4,5)-steroid 5-beta-reductase activity&apos; SubClassOf &apos;enone reductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035639</classIRI>
<classLabel>purine ribonucleoside triphosphate binding</classLabel>
<newAxiom>&apos;purine ribonucleoside triphosphate binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045016</classIRI>
<classLabel>mitochondrial magnesium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial magnesium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial magnesium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033054</classIRI>
<classLabel>D-glutamate metabolic process</classLabel>
<deletedAxiom>&apos;D-glutamate metabolic process&apos; SubClassOf &apos;macromolecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033052</classIRI>
<classLabel>cyanoamino acid metabolic process</classLabel>
<deletedAxiom>&apos;cyanoamino acid metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cyanoamino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045041</classIRI>
<classLabel>protein import into mitochondrial intermembrane space</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070025</classIRI>
<classLabel>carbon monoxide binding</classLabel>
<deletedAxiom>&apos;carbon monoxide binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;carbon monoxide binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070026</classIRI>
<classLabel>nitric oxide binding</classLabel>
<deletedAxiom>&apos;nitric oxide binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;nitric oxide binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045087</classIRI>
<classLabel>innate immune response</classLabel>
<deletedAxiom>&apos;innate immune response&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;innate immune response&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035518</classIRI>
<classLabel>histone H2A monoubiquitination</classLabel>
<deletedAxiom>&apos;histone H2A monoubiquitination&apos; SubClassOf &apos;histone monoubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H2A monoubiquitination&apos; SubClassOf &apos;histone H2A ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035521</classIRI>
<classLabel>monoubiquitinated histone deubiquitination</classLabel>
<deletedAxiom>&apos;monoubiquitinated histone deubiquitination&apos; SubClassOf &apos;histone deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;monoubiquitinated histone deubiquitination&apos; SubClassOf &apos;monoubiquitinated protein deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035522</classIRI>
<classLabel>monoubiquitinated histone H2A deubiquitination</classLabel>
<deletedAxiom>&apos;monoubiquitinated histone H2A deubiquitination&apos; SubClassOf &apos;monoubiquitinated histone deubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072570</classIRI>
<classLabel>ADP-D-ribose binding</classLabel>
<newAxiom>&apos;ADP-D-ribose binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106314</classIRI>
<classLabel>nitrite reductase NADPH activity</classLabel>
<deletedAxiom>&apos;nitrite reductase NADPH activity&apos; SubClassOf &apos;nitrite reductase [NAD(P)H] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106316</classIRI>
<classLabel>nitrite reductase NADH activity</classLabel>
<deletedAxiom>&apos;nitrite reductase NADH activity&apos; SubClassOf &apos;nitrite reductase [NAD(P)H] activity&apos;</deletedAxiom>
<newAxiom>&apos;nitrite reductase NADH activity&apos; SubClassOf &apos;nitrite reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047410</classIRI>
<classLabel>N-formylmethionylaminoacyl-tRNA deformylase activity</classLabel>
<deletedAxiom>&apos;N-formylmethionylaminoacyl-tRNA deformylase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047409</classIRI>
<classLabel>alkenylglycerophosphoethanolamine hydrolase activity</classLabel>
<deletedAxiom>&apos;alkenylglycerophosphoethanolamine hydrolase activity&apos; SubClassOf &apos;ether hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035498</classIRI>
<classLabel>carnosine metabolic process</classLabel>
<newAxiom>&apos;carnosine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060395</classIRI>
<classLabel>SMAD protein signal transduction</classLabel>
<deletedAxiom>&apos;SMAD protein signal transduction&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;SMAD protein signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098994</classIRI>
<classLabel>disruption of host cell envelope during viral entry</classLabel>
<newAxiom>&apos;disruption of host cell envelope during viral entry&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098995</classIRI>
<classLabel>disruption by virus of host envelope lipopolysaccharide during virus entry</classLabel>
<deletedAxiom>&apos;disruption by virus of host envelope lipopolysaccharide during virus entry&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098932</classIRI>
<classLabel>disruption by virus of host cell wall peptidoglycan during virus entry</classLabel>
<deletedAxiom>&apos;disruption by virus of host cell wall peptidoglycan during virus entry&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050992</classIRI>
<classLabel>dimethylallyl diphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;dimethylallyl diphosphate biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;dimethylallyl diphosphate biosynthetic process&apos; SubClassOf &apos;phospholipid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050993</classIRI>
<classLabel>dimethylallyl diphosphate metabolic process</classLabel>
<deletedAxiom>&apos;dimethylallyl diphosphate metabolic process&apos; SubClassOf &apos;phosphorus metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dimethylallyl diphosphate metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;dimethylallyl diphosphate metabolic process&apos; SubClassOf &apos;phospholipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047379</classIRI>
<classLabel>ADP-dependent short-chain-acyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;ADP-dependent short-chain-acyl-CoA hydrolase activity&apos; SubClassOf &apos;acyl-CoA hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047381</classIRI>
<classLabel>dodecanoyl-[acyl-carrier-protein] hydrolase activity</classLabel>
<deletedAxiom>&apos;dodecanoyl-[acyl-carrier-protein] hydrolase activity&apos; SubClassOf &apos;acyl-[acyl-carrier-protein] hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047380</classIRI>
<classLabel>ADP-dependent medium-chain-acyl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;ADP-dependent medium-chain-acyl-CoA hydrolase activity&apos; SubClassOf &apos;medium-chain acyl-CoA hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050833</classIRI>
<classLabel>pyruvate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;pyruvate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050837</classIRI>
<classLabel>peptide cross-linking via L-cysteinyl-L-selenocysteine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-cysteinyl-L-selenocysteine&apos; SubClassOf &apos;peptidyl-selenocysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteinyl-L-selenocysteine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteinyl-L-selenocysteine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035276</classIRI>
<classLabel>ethanol binding</classLabel>
<newAxiom>&apos;ethanol binding&apos; SubClassOf &apos;anion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035299</classIRI>
<classLabel>inositol pentakisphosphate 2-kinase activity</classLabel>
<deletedAxiom>&apos;inositol pentakisphosphate 2-kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol pentakisphosphate 2-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060153</classIRI>
<classLabel>perturbation by virus of host cell cycle progression</classLabel>
<deletedAxiom>&apos;perturbation by virus of host cell cycle progression&apos; SubClassOf &apos;perturbation by virus of host cell cycle regulation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060141</classIRI>
<classLabel>positive regulation of syncytium formation by virus</classLabel>
<newAxiom>&apos;positive regulation of syncytium formation by virus&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098720</classIRI>
<classLabel>succinate import across plasma membrane</classLabel>
<deletedAxiom>&apos;succinate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098721</classIRI>
<classLabel>uracil import across plasma membrane</classLabel>
<deletedAxiom>&apos;uracil import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098739</classIRI>
<classLabel>import across plasma membrane</classLabel>
<newAxiom>&apos;import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050745</classIRI>
<classLabel>peptide cross-linking via L-cysteinyl-5-imidazolinone glycine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via L-cysteinyl-5-imidazolinone glycine&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via L-cysteinyl-5-imidazolinone glycine&apos; SubClassOf &apos;peptide cross-linking via 5-imidazolinone glycine&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098702</classIRI>
<classLabel>adenine import across plasma membrane</classLabel>
<deletedAxiom>&apos;adenine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098703</classIRI>
<classLabel>calcium ion import across plasma membrane</classLabel>
<newAxiom>&apos;calcium ion import across plasma membrane&apos; SubClassOf &apos;calcium ion import&apos;</newAxiom>
<newAxiom>&apos;calcium ion import across plasma membrane&apos; SubClassOf &apos;calcium ion import into cytosol&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098704</classIRI>
<classLabel>carbohydrate import across plasma membrane</classLabel>
<deletedAxiom>&apos;carbohydrate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098709</classIRI>
<classLabel>glutathione import across plasma membrane</classLabel>
<deletedAxiom>&apos;glutathione import across plasma membrane&apos; SubClassOf &apos;import across plasma membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;glutathione import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
<newAxiom>&apos;glutathione import across plasma membrane&apos; SubClassOf &apos;tripeptide import across plasma membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098710</classIRI>
<classLabel>guanine import across plasma membrane</classLabel>
<deletedAxiom>&apos;guanine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098714</classIRI>
<classLabel>malate import across plasma membrane</classLabel>
<deletedAxiom>&apos;malate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098715</classIRI>
<classLabel>malonic acid import across plasma membrane</classLabel>
<deletedAxiom>&apos;malonic acid import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050739</classIRI>
<classLabel>peptide cross-linking via S-[5&apos;-(L-tryptoph-6&apos;-yl)-L-tyrosin-3&apos;-yl]-L-methionin-S-ium</classLabel>
<deletedAxiom>&apos;peptide cross-linking via S-[5&apos;-(L-tryptoph-6&apos;-yl)-L-tyrosin-3&apos;-yl]-L-methionin-S-ium&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-[5&apos;-(L-tryptoph-6&apos;-yl)-L-tyrosin-3&apos;-yl]-L-methionin-S-ium&apos; SubClassOf &apos;peptidyl-tryptophan modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-[5&apos;-(L-tryptoph-6&apos;-yl)-L-tyrosin-3&apos;-yl]-L-methionin-S-ium&apos; SubClassOf &apos;peptidyl-methionine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via S-[5&apos;-(L-tryptoph-6&apos;-yl)-L-tyrosin-3&apos;-yl]-L-methionin-S-ium&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098717</classIRI>
<classLabel>pantothenate import across plasma membrane</classLabel>
<deletedAxiom>&apos;pantothenate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035071</classIRI>
<classLabel>salivary gland cell autophagic cell death</classLabel>
<deletedAxiom>&apos;salivary gland cell autophagic cell death&apos; SubClassOf &apos;autophagic cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;salivary gland cell autophagic cell death&apos; SubClassOf &apos;programmed cell death involved in cell development&apos;</deletedAxiom>
<deletedAxiom>&apos;salivary gland cell autophagic cell death&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;salivary gland histolysis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035072</classIRI>
<classLabel>ecdysone-mediated induction of salivary gland cell autophagic cell death</classLabel>
<deletedAxiom>&apos;ecdysone-mediated induction of salivary gland cell autophagic cell death&apos; SubClassOf &apos;induction of programmed cell death by ecdysone&apos;</deletedAxiom>
<deletedAxiom>&apos;ecdysone-mediated induction of salivary gland cell autophagic cell death&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;salivary gland cell autophagic cell death&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035066</classIRI>
<classLabel>positive regulation of histone acetylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone acetylation&apos; SubClassOf &apos;regulation of histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone acetylation&apos; SubClassOf &apos;positive regulation of peptidyl-lysine acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone acetylation&apos; SubClassOf &apos;positive regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035067</classIRI>
<classLabel>negative regulation of histone acetylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone acetylation&apos; SubClassOf &apos;negative regulation of post-translational protein modification&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone acetylation&apos; SubClassOf &apos;regulation of histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone acetylation&apos; SubClassOf &apos;negative regulation of peptidyl-lysine acetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035065</classIRI>
<classLabel>regulation of histone acetylation</classLabel>
<deletedAxiom>&apos;regulation of histone acetylation&apos; SubClassOf &apos;regulation of peptidyl-lysine acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone acetylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone acetylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone acetylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone acetylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone acetylation&apos; SubClassOf &apos;regulation of histone modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098672</classIRI>
<classLabel>inhibition of host CRISPR-cas system by virus</classLabel>
<deletedAxiom>&apos;inhibition of host CRISPR-cas system by virus&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;CRISPR-cas system&apos;</deletedAxiom>
<deletedAxiom>&apos;inhibition of host CRISPR-cas system by virus&apos; SubClassOf &apos;virus-mediated perturbation of host defense response&apos;</deletedAxiom>
<newAxiom>&apos;inhibition of host CRISPR-cas system by virus&apos; SubClassOf &apos;suppression of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098633</classIRI>
<classLabel>collagen fibril binding</classLabel>
<deletedAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;collagen fibril binding&apos; SubClassOf &apos;extracellular matrix binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905130</classIRI>
<classLabel>carcinine import across plasma membrane</classLabel>
<deletedAxiom>&apos;carcinine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905135</classIRI>
<classLabel>biotin import across plasma membrane</classLabel>
<deletedAxiom>&apos;biotin import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905136</classIRI>
<classLabel>dethiobiotin import across plasma membrane</classLabel>
<deletedAxiom>&apos;dethiobiotin import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905144</classIRI>
<classLabel>response to acetylcholine</classLabel>
<deletedAxiom>&apos;response to acetylcholine&apos; SubClassOf &apos;response to organonitrogen compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to acetylcholine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
<newAxiom>&apos;response to acetylcholine&apos; SubClassOf &apos;response to organic substance&apos;</newAxiom>
<newAxiom>&apos;response to acetylcholine&apos; SubClassOf &apos;response to nitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905145</classIRI>
<classLabel>cellular response to acetylcholine</classLabel>
<deletedAxiom>&apos;cellular response to acetylcholine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to acetylcholine&apos; SubClassOf &apos;cellular response to organonitrogen compound&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to acetylcholine&apos; SubClassOf &apos;cellular response to nitrogen compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905279</classIRI>
<classLabel>regulation of retrograde transport, endosome to Golgi</classLabel>
<deletedAxiom>&apos;regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905280</classIRI>
<classLabel>negative regulation of retrograde transport, endosome to Golgi</classLabel>
<deletedAxiom>&apos;negative regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;negative regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905281</classIRI>
<classLabel>positive regulation of retrograde transport, endosome to Golgi</classLabel>
<deletedAxiom>&apos;positive regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;positive regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of retrograde transport, endosome to Golgi&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050665</classIRI>
<classLabel>hydrogen peroxide biosynthetic process</classLabel>
<deletedAxiom>&apos;hydrogen peroxide biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050667</classIRI>
<classLabel>homocysteine metabolic process</classLabel>
<newAxiom>&apos;homocysteine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035024</classIRI>
<classLabel>negative regulation of Rho protein signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of Rho protein signal transduction&apos; SubClassOf &apos;negative regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of Rho protein signal transduction&apos; SubClassOf &apos;negative regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035025</classIRI>
<classLabel>positive regulation of Rho protein signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of Rho protein signal transduction&apos; SubClassOf &apos;positive regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of Rho protein signal transduction&apos; SubClassOf &apos;positive regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035022</classIRI>
<classLabel>positive regulation of Rac protein signal transduction</classLabel>
<deletedAxiom>&apos;positive regulation of Rac protein signal transduction&apos; SubClassOf &apos;positive regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of Rac protein signal transduction&apos; SubClassOf &apos;positive regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035023</classIRI>
<classLabel>regulation of Rho protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Rho protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of Rho protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035020</classIRI>
<classLabel>regulation of Rac protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Rac protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of Rac protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035021</classIRI>
<classLabel>negative regulation of Rac protein signal transduction</classLabel>
<deletedAxiom>&apos;negative regulation of Rac protein signal transduction&apos; SubClassOf &apos;negative regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of Rac protein signal transduction&apos; SubClassOf &apos;negative regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098532</classIRI>
<classLabel>histone H3-K27 trimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K27 trimethylation&apos; SubClassOf &apos;histone H3-K27 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050562</classIRI>
<classLabel>lysine-tRNA(Pyl) ligase activity</classLabel>
<deletedAxiom>&apos;lysine-tRNA(Pyl) ligase activity&apos; SubClassOf &apos;aminoacyl-tRNA ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001692</classIRI>
<classLabel>histamine metabolic process</classLabel>
<deletedAxiom>&apos;histamine metabolic process&apos; SubClassOf &apos;phosphate-containing compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905232</classIRI>
<classLabel>cellular response to L-glutamate</classLabel>
<deletedAxiom>&apos;cellular response to L-glutamate&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905243</classIRI>
<classLabel>cellular response to 3,3&apos;,5-triiodo-L-thyronine</classLabel>
<deletedAxiom>&apos;cellular response to 3,3&apos;,5-triiodo-L-thyronine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905242</classIRI>
<classLabel>response to 3,3&apos;,5-triiodo-L-thyronine</classLabel>
<deletedAxiom>&apos;response to 3,3&apos;,5-triiodo-L-thyronine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905376</classIRI>
<classLabel>negative regulation of cytochrome-c oxidase activity</classLabel>
<newAxiom>&apos;negative regulation of cytochrome-c oxidase activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050436</classIRI>
<classLabel>microfibril binding</classLabel>
<deletedAxiom>&apos;microfibril binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;microfibril binding&apos; SubClassOf &apos;extracellular matrix binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905427</classIRI>
<classLabel>intracellular signal transduction involved in positive regulation of cell growth</classLabel>
<deletedAxiom>&apos;intracellular signal transduction involved in positive regulation of cell growth&apos; EquivalentTo &apos;intracellular signal transduction&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cell growth&apos;)</deletedAxiom>
<deletedAxiom>&apos;intracellular signal transduction involved in positive regulation of cell growth&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cell growth&apos;</deletedAxiom>
<deletedAxiom>&apos;intracellular signal transduction involved in positive regulation of cell growth&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905439</classIRI>
<classLabel>response to chondroitin 6&apos;-sulfate</classLabel>
<deletedAxiom>&apos;response to chondroitin 6&apos;-sulfate&apos; SubClassOf &apos;response to monosaccharide&apos;</deletedAxiom>
<newAxiom>&apos;response to chondroitin 6&apos;-sulfate&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905441</classIRI>
<classLabel>response to chondroitin 4&apos;-sulfate</classLabel>
<deletedAxiom>&apos;response to chondroitin 4&apos;-sulfate&apos; SubClassOf &apos;response to monosaccharide&apos;</deletedAxiom>
<newAxiom>&apos;response to chondroitin 4&apos;-sulfate&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905442</classIRI>
<classLabel>cellular response to chondroitin 4&apos;-sulfate</classLabel>
<deletedAxiom>&apos;cellular response to chondroitin 4&apos;-sulfate&apos; SubClassOf &apos;cellular response to monosaccharide stimulus&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to chondroitin 4&apos;-sulfate&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905440</classIRI>
<classLabel>cellular response to chondroitin 6&apos;-sulfate</classLabel>
<deletedAxiom>&apos;cellular response to chondroitin 6&apos;-sulfate&apos; SubClassOf &apos;cellular response to monosaccharide stimulus&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to chondroitin 6&apos;-sulfate&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003908</classIRI>
<classLabel>methylated-DNA-[protein]-cysteine S-methyltransferase activity</classLabel>
<newAxiom>&apos;methylated-DNA-[protein]-cysteine S-methyltransferase activity&apos; SubClassOf &apos;protein methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015942</classIRI>
<classLabel>formate metabolic process</classLabel>
<deletedAxiom>&apos;formate metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050218</classIRI>
<classLabel>propionate-CoA ligase activity</classLabel>
<deletedAxiom>&apos;propionate-CoA ligase activity&apos; SubClassOf &apos;acid-thiol ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;propionate-CoA ligase activity&apos; SubClassOf &apos;CoA-ligase activity&apos;</deletedAxiom>
<newAxiom>&apos;propionate-CoA ligase activity&apos; SubClassOf &apos;short-chain fatty acid-CoA ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050245</classIRI>
<classLabel>quercitrinase activity</classLabel>
<deletedAxiom>&apos;quercitrinase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015871</classIRI>
<classLabel>choline transport</classLabel>
<deletedAxiom>&apos;choline transport&apos; SubClassOf &apos;quaternary ammonium group transport&apos;</deletedAxiom>
<newAxiom>&apos;choline transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015870</classIRI>
<classLabel>acetylcholine transport</classLabel>
<deletedAxiom>&apos;acetylcholine transport&apos; SubClassOf &apos;quaternary ammonium group transport&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052859</classIRI>
<classLabel>glucan endo-1,4-beta-glucosidase activity</classLabel>
<deletedAxiom>&apos;glucan endo-1,4-beta-glucosidase activity&apos; SubClassOf &apos;beta-glucosidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052836</classIRI>
<classLabel>inositol 5-diphosphate pentakisphosphate 5-kinase activity</classLabel>
<deletedAxiom>&apos;inositol 5-diphosphate pentakisphosphate 5-kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol 5-diphosphate pentakisphosphate 5-kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052839</classIRI>
<classLabel>inositol diphosphate tetrakisphosphate kinase activity</classLabel>
<deletedAxiom>&apos;inositol diphosphate tetrakisphosphate kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;inositol diphosphate tetrakisphosphate kinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180030</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062133</classIRI>
<classLabel>negative regulation of L-glutamine biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of L-glutamine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086102</classIRI>
<classLabel>adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate</classLabel>
<deletedAxiom>&apos;adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate&apos; SubClassOf &apos;adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate&apos; SubClassOf &apos;G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate&apos; EquivalentTo &apos;adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;negative regulation of heart rate&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062143</classIRI>
<classLabel>L-propargylglycine biosynthetic process</classLabel>
<deletedAxiom>&apos;L-propargylglycine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-propargylglycine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;L-propargylglycine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062142</classIRI>
<classLabel>L-beta-ethynylserine biosynthetic process</classLabel>
<deletedAxiom>&apos;L-beta-ethynylserine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-beta-ethynylserine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;L-beta-ethynylserine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905665</classIRI>
<classLabel>positive regulation of calcium ion import across plasma membrane</classLabel>
<newAxiom>&apos;positive regulation of calcium ion import across plasma membrane&apos; SubClassOf &apos;positive regulation of calcium ion import&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062134</classIRI>
<classLabel>positive regulation of L-glutamine biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of L-glutamine biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905664</classIRI>
<classLabel>regulation of calcium ion import across plasma membrane</classLabel>
<newAxiom>&apos;regulation of calcium ion import across plasma membrane&apos; SubClassOf &apos;regulation of calcium ion import&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003860</classIRI>
<classLabel>3-hydroxyisobutyryl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;3-hydroxyisobutyryl-CoA hydrolase activity&apos; SubClassOf &apos;CoA hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;3-hydroxyisobutyryl-CoA hydrolase activity&apos; SubClassOf &apos;short-chain-acyl-CoA dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003853</classIRI>
<classLabel>2-methylacyl-CoA dehydrogenase activity</classLabel>
<deletedAxiom>&apos;2-methylacyl-CoA dehydrogenase activity&apos; SubClassOf &apos;acyl-CoA dehydrogenase activity&apos;</deletedAxiom>
<newAxiom>&apos;2-methylacyl-CoA dehydrogenase activity&apos; SubClassOf &apos;short-chain-acyl-CoA dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903071</classIRI>
<classLabel>positive regulation of ER-associated ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;positive regulation of ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;ubiquitin-dependent ERAD pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ubiquitin-dependent ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903070</classIRI>
<classLabel>negative regulation of ER-associated ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;negative regulation of proteasomal ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ubiquitin-dependent ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;negative regulation of ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;ubiquitin-dependent ERAD pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903075</classIRI>
<classLabel>pyridoxine import across plasma membrane</classLabel>
<deletedAxiom>&apos;pyridoxine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903069</classIRI>
<classLabel>regulation of ER-associated ubiquitin-dependent protein catabolic process</classLabel>
<deletedAxiom>&apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;regulation of ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;ubiquitin-dependent ERAD pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf &apos;regulation of proteasomal ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ER-associated ubiquitin-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ubiquitin-dependent ERAD pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086094</classIRI>
<classLabel>positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction</classLabel>
<deletedAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction&apos; SubClassOf &apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cardiac muscle contraction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086096</classIRI>
<classLabel>adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;G protein-coupled receptor signaling pathway involved in heart process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990417</classIRI>
<classLabel>snoRNA release from pre-rRNA</classLabel>
<deletedAxiom>&apos;snoRNA release from pre-rRNA&apos; SubClassOf &apos;sno(s)RNA metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015701</classIRI>
<classLabel>bicarbonate transport</classLabel>
<deletedAxiom>&apos;bicarbonate transport&apos; SubClassOf &apos;one-carbon compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015709</classIRI>
<classLabel>thiosulfate transport</classLabel>
<deletedAxiom>&apos;thiosulfate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015724</classIRI>
<classLabel>formate transport</classLabel>
<deletedAxiom>&apos;formate transport&apos; SubClassOf &apos;one-carbon compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;formate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015728</classIRI>
<classLabel>mevalonate transport</classLabel>
<deletedAxiom>&apos;mevalonate transport&apos; SubClassOf &apos;organic hydroxy compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;mevalonate transport&apos; SubClassOf &apos;monocarboxylic acid transport&apos;</deletedAxiom>
<newAxiom>&apos;mevalonate transport&apos; SubClassOf &apos;transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015730</classIRI>
<classLabel>propanoate transmembrane transport</classLabel>
<deletedAxiom>&apos;propanoate transmembrane transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039707</classIRI>
<classLabel>virus-mediated pore formation in host cell membrane</classLabel>
<deletedAxiom>&apos;virus-mediated pore formation in host cell membrane&apos; SubClassOf &apos;viral process&apos;</deletedAxiom>
<deletedAxiom>&apos;virus-mediated pore formation in host cell membrane&apos; SubClassOf &apos;symbiont-mediated pore formation in host plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015745</classIRI>
<classLabel>tartrate transmembrane transport</classLabel>
<deletedAxiom>&apos;tartrate transmembrane transport&apos; SubClassOf &apos;sulfur compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015746</classIRI>
<classLabel>citrate transport</classLabel>
<deletedAxiom>&apos;citrate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039722</classIRI>
<classLabel>suppression by virus of host toll-like receptor signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host toll-like receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host toll-like receptor signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host toll-like receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052709</classIRI>
<classLabel>N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process</classLabel>
<deletedAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052708</classIRI>
<classLabel>N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process</classLabel>
<deletedAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052710</classIRI>
<classLabel>N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process</classLabel>
<deletedAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039678</classIRI>
<classLabel>viral genome ejection through host cell envelope</classLabel>
<deletedAxiom>&apos;viral genome ejection through host cell envelope&apos; SubClassOf &apos;viral entry into host cell&apos;</deletedAxiom>
<newAxiom>&apos;viral genome ejection through host cell envelope&apos; SubClassOf &apos;viral process&apos;</newAxiom>
<newAxiom>&apos;viral genome ejection through host cell envelope&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039672</classIRI>
<classLabel>suppression by virus of host natural killer cell activation</classLabel>
<newAxiom>&apos;suppression by virus of host natural killer cell activation&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039668</classIRI>
<classLabel>viral entry into host cell via pilus basal pore</classLabel>
<deletedAxiom>&apos;viral entry into host cell via pilus basal pore&apos; SubClassOf &apos;viral entry into host cell via pilus retraction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039669</classIRI>
<classLabel>viral entry into host cell via pilus retraction and membrane fusion</classLabel>
<deletedAxiom>&apos;viral entry into host cell via pilus retraction and membrane fusion&apos; SubClassOf &apos;viral entry into host cell via pilus retraction&apos;</deletedAxiom>
<deletedAxiom>&apos;viral entry into host cell via pilus retraction and membrane fusion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fusion of virus membrane with host plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039666</classIRI>
<classLabel>virion attachment to host cell pilus</classLabel>
<newAxiom>&apos;virion attachment to host cell pilus&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039667</classIRI>
<classLabel>viral entry into host cell via pilus retraction</classLabel>
<deletedAxiom>&apos;viral entry into host cell via pilus retraction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pilus retraction&apos;</deletedAxiom>
<deletedAxiom>&apos;viral entry into host cell via pilus retraction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;transport of virus&apos;</deletedAxiom>
<deletedAxiom>&apos;viral entry into host cell via pilus retraction&apos; SubClassOf &apos;viral entry into host cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039699</classIRI>
<classLabel>viral mRNA cap methylation</classLabel>
<deletedAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</deletedAxiom>
<newAxiom>&apos;viral mRNA cap methylation&apos; SubClassOf &apos;evasion of host innate immune recognition&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904447</classIRI>
<classLabel>folate import across plasma membrane</classLabel>
<deletedAxiom>&apos;folate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0086024</classIRI>
<classLabel>adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate</classLabel>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; SubClassOf &apos;positive regulation of heart rate by epinephrine-norepinephrine&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; EquivalentTo &apos;adenylate cyclase-activating adrenergic receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of heart rate&apos;)</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; SubClassOf &apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of heart rate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904493</classIRI>
<classLabel>tetrahydrofolyl-poly(glutamate) polymer binding</classLabel>
<deletedAxiom>&apos;tetrahydrofolyl-poly(glutamate) polymer binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;tetrahydrofolyl-poly(glutamate) polymer binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003712</classIRI>
<classLabel>transcription coregulator activity</classLabel>
<newAxiom>&apos;transcription coregulator activity&apos; SubClassOf &apos;protein-macromolecule adaptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990554</classIRI>
<classLabel>mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990553</classIRI>
<classLabel>mitochondrial 5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial 5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990551</classIRI>
<classLabel>mitochondrial 2-oxoadipate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 2-oxoadipate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial 2-oxoadipate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990550</classIRI>
<classLabel>mitochondrial alpha-ketoglutarate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial alpha-ketoglutarate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial alpha-ketoglutarate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990549</classIRI>
<classLabel>mitochondrial NAD transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial NAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial NAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990548</classIRI>
<classLabel>mitochondrial FAD transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial FAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial FAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990547</classIRI>
<classLabel>mitochondrial phosphate ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial phosphate ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial phosphate ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990546</classIRI>
<classLabel>mitochondrial tricarboxylic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial tricarboxylic acid transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial tricarboxylic acid transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990545</classIRI>
<classLabel>mitochondrial thiamine pyrophosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990544</classIRI>
<classLabel>mitochondrial ATP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ATP transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial ATP transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990543</classIRI>
<classLabel>mitochondrial S-adenosyl-L-methionine transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990540</classIRI>
<classLabel>mitochondrial manganese ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial manganese ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial manganese ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990575</classIRI>
<classLabel>mitochondrial L-ornithine transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial L-ornithine transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial L-ornithine transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990559</classIRI>
<classLabel>mitochondrial coenzyme A transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial coenzyme A transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial coenzyme A transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990558</classIRI>
<classLabel>mitochondrial malonate(1-) transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial malonate(1-) transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial malonate(1-) transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990557</classIRI>
<classLabel>mitochondrial sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990556</classIRI>
<classLabel>mitochondrial isopropylmalate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial isopropylmalate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial isopropylmalate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990555</classIRI>
<classLabel>mitochondrial oxaloacetate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial oxaloacetate transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial oxaloacetate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990519</classIRI>
<classLabel>pyrimidine nucleotide import into mitochondrion</classLabel>
<deletedAxiom>&apos;pyrimidine nucleotide import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;pyrimidine nucleotide import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039604</classIRI>
<classLabel>suppression by virus of host translation</classLabel>
<newAxiom>&apos;suppression by virus of host translation&apos; SubClassOf &apos;suppression by virus of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015654</classIRI>
<classLabel>tellurite transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;tellurite transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015689</classIRI>
<classLabel>molybdate ion transport</classLabel>
<deletedAxiom>&apos;molybdate ion transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039653</classIRI>
<classLabel>suppression by virus of host transcription</classLabel>
<deletedAxiom>&apos;suppression by virus of host transcription&apos; SubClassOf &apos;modulation by virus of host transcription&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host transcription&apos; SubClassOf &apos;modulation by symbiont of host transcription&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039656</classIRI>
<classLabel>modulation by virus of host gene expression</classLabel>
<deletedAxiom>&apos;modulation by virus of host gene expression&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;gene expression&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host gene expression&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host gene expression&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;gene expression&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host gene expression&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039652</classIRI>
<classLabel>induction by virus of host NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;induction by virus of host NF-kappaB cascade&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host NF-kappaB cascade&apos; SubClassOf &apos;induction of host canonical NF-kappaB signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039646</classIRI>
<classLabel>perturbation by virus of host G0/G1 transition checkpoint</classLabel>
<deletedAxiom>&apos;perturbation by virus of host G0/G1 transition checkpoint&apos; SubClassOf &apos;perturbation by virus of host cell cycle progression&apos;</deletedAxiom>
<newAxiom>&apos;perturbation by virus of host G0/G1 transition checkpoint&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039648</classIRI>
<classLabel>modulation by symbiont of host protein ubiquitination</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host protein ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host protein ubiquitination&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host protein ubiquitination&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host protein ubiquitination&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039644</classIRI>
<classLabel>suppression by virus of host NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;suppression by virus of host NF-kappaB cascade&apos; SubClassOf &apos;virus-mediated perturbation of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host NF-kappaB cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host canonical NF-kappaB cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039645</classIRI>
<classLabel>perturbation by virus of host G1/S transition checkpoint</classLabel>
<deletedAxiom>&apos;perturbation by virus of host G1/S transition checkpoint&apos; SubClassOf &apos;perturbation by virus of host cell cycle progression&apos;</deletedAxiom>
<newAxiom>&apos;perturbation by virus of host G1/S transition checkpoint&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039573</classIRI>
<classLabel>suppression by virus of host complement activation</classLabel>
<deletedAxiom>&apos;suppression by virus of host complement activation&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;complement activation&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host complement activation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;complement activation&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host complement activation&apos; SubClassOf &apos;perturbation by virus of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039595</classIRI>
<classLabel>induction by virus of catabolism of host mRNA</classLabel>
<deletedAxiom>&apos;induction by virus of catabolism of host mRNA&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;induction by virus of catabolism of host mRNA&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</newAxiom>
<newAxiom>&apos;induction by virus of catabolism of host mRNA&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039592</classIRI>
<classLabel>perturbation by virus of G2/M transition of host mitotic cell cycle</classLabel>
<deletedAxiom>&apos;perturbation by virus of G2/M transition of host mitotic cell cycle&apos; SubClassOf &apos;perturbation by virus of host cell cycle progression&apos;</deletedAxiom>
<newAxiom>&apos;perturbation by virus of G2/M transition of host mitotic cell cycle&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039593</classIRI>
<classLabel>peturbation by virus of host exit from mitosis</classLabel>
<deletedAxiom>&apos;peturbation by virus of host exit from mitosis&apos; SubClassOf &apos;perturbation by virus of host cell cycle progression&apos;</deletedAxiom>
<newAxiom>&apos;peturbation by virus of host exit from mitosis&apos; SubClassOf &apos;perturbation of host cell cycle progression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039585</classIRI>
<classLabel>PKR-mediated signaling</classLabel>
<deletedAxiom>&apos;PKR-mediated signaling&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;PKR-mediated signaling&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039580</classIRI>
<classLabel>suppression by virus of host PKR signaling</classLabel>
<deletedAxiom>&apos;suppression by virus of host PKR signaling&apos; SubClassOf &apos;suppression by virus of host innate immune response&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host PKR signaling&apos; SubClassOf &apos;modulation by virus of host translation&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host PKR signaling&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
<newAxiom>&apos;suppression by virus of host PKR signaling&apos; SubClassOf &apos;suppression by virus of host translation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052559</classIRI>
<classLabel>induction by symbiont of host immune response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052594</classIRI>
<classLabel>aminoacetone:oxygen oxidoreductase(deaminating) activity</classLabel>
<deletedAxiom>&apos;aminoacetone:oxygen oxidoreductase(deaminating) activity&apos; SubClassOf &apos;aliphatic amine oxidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aminoacetone:oxygen oxidoreductase(deaminating) activity&apos; SubClassOf &apos;primary amine oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052593</classIRI>
<classLabel>tryptamine:oxygen oxidoreductase (deaminating) activity</classLabel>
<deletedAxiom>&apos;tryptamine:oxygen oxidoreductase (deaminating) activity&apos; SubClassOf &apos;aliphatic amine oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052596</classIRI>
<classLabel>phenethylamine:oxygen oxidoreductase (deaminating) activity</classLabel>
<deletedAxiom>&apos;phenethylamine:oxygen oxidoreductase (deaminating) activity&apos; SubClassOf &apos;primary amine oxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990679</classIRI>
<classLabel>histone H4-K12 deacetylation</classLabel>
<deletedAxiom>&apos;histone H4-K12 deacetylation&apos; SubClassOf &apos;histone H4 deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990678</classIRI>
<classLabel>histone H4-K16 deacetylation</classLabel>
<deletedAxiom>&apos;histone H4-K16 deacetylation&apos; SubClassOf &apos;histone H4 deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990619</classIRI>
<classLabel>histone H3-K9 deacetylation</classLabel>
<deletedAxiom>&apos;histone H3-K9 deacetylation&apos; SubClassOf &apos;histone H3 deacetylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990616</classIRI>
<classLabel>magnesium ion export from mitochondrion</classLabel>
<newAxiom>&apos;magnesium ion export from mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170037</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015501</classIRI>
<classLabel>glutamate:sodium symporter activity</classLabel>
<deletedAxiom>&apos;glutamate:sodium symporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039507</classIRI>
<classLabel>suppression by virus of host molecular function</classLabel>
<deletedAxiom>&apos;suppression by virus of host molecular function&apos; SubClassOf &apos;modulation by virus of host catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host molecular function&apos; SubClassOf &apos;negative regulation by symbiont of host catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host molecular function&apos; SubClassOf &apos;modulation by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039514</classIRI>
<classLabel>disruption by virus of host JAK-STAT cascade</classLabel>
<deletedAxiom>&apos;disruption by virus of host JAK-STAT cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host JAK-STAT cascade&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host JAK-STAT cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039516</classIRI>
<classLabel>modulation by virus of host catalytic activity</classLabel>
<deletedAxiom>&apos;modulation by virus of host catalytic activity&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host catalytic activity&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host catalytic activity&apos; SubClassOf &apos;modulation by symbiont of host catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039513</classIRI>
<classLabel>suppression by virus of host catalytic activity</classLabel>
<deletedAxiom>&apos;suppression by virus of host catalytic activity&apos; SubClassOf &apos;suppression by virus of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039504</classIRI>
<classLabel>suppression by virus of host adaptive immune response</classLabel>
<deletedAxiom>&apos;suppression by virus of host adaptive immune response&apos; SubClassOf &apos;virus-mediated perturbation of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039505</classIRI>
<classLabel>suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II</classLabel>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;negative regulation of antigen processing and presentation of peptide antigen via MHC class II&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;antigen processing and presentation of peptide antigen via MHC class II&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039506</classIRI>
<classLabel>modulation by virus of host molecular function</classLabel>
<deletedAxiom>&apos;modulation by virus of host molecular function&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;molecular_function&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host molecular function&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host molecular function&apos; SubClassOf &apos;modulation by symbiont of host molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904734</classIRI>
<classLabel>positive regulation of electron transfer activity</classLabel>
<deletedAxiom>&apos;positive regulation of electron transfer activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of electron transfer activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015552</classIRI>
<classLabel>propionate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;propionate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904732</classIRI>
<classLabel>regulation of electron transfer activity</classLabel>
<deletedAxiom>&apos;regulation of electron transfer activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of electron transfer activity&apos; SubClassOf &apos;regulation of molecular function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039502</classIRI>
<classLabel>suppression by virus of host type I interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;type I interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;type I interferon-mediated signaling pathway&apos;)</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type I interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904733</classIRI>
<classLabel>negative regulation of electron transfer activity</classLabel>
<deletedAxiom>&apos;negative regulation of electron transfer activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of electron transfer activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039537</classIRI>
<classLabel>suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway</classLabel>
<newAxiom>&apos;suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039525</classIRI>
<classLabel>modulation by virus of host chromatin organization</classLabel>
<deletedAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf &apos;modulation by virus of host process&apos;</newAxiom>
<newAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039527</classIRI>
<classLabel>disruption by virus of host TRAF-mediated signal transduction</classLabel>
<deletedAxiom>&apos;disruption by virus of host TRAF-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host TRAF-mediated signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;disruption by virus of host TRAF-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039524</classIRI>
<classLabel>suppression by virus of host mRNA processing</classLabel>
<deletedAxiom>&apos;suppression by virus of host mRNA processing&apos; SubClassOf &apos;negative regulation of mRNA processing&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host mRNA processing&apos; SubClassOf &apos;modification by virus of host mRNA processing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015499</classIRI>
<classLabel>formate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;formate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904679</classIRI>
<classLabel>myo-inositol import across plasma membrane</classLabel>
<deletedAxiom>&apos;myo-inositol import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052489</classIRI>
<classLabel>negative regulation by host of symbiont programmed cell death</classLabel>
<deletedAxiom>&apos;negative regulation by host of symbiont programmed cell death&apos; SubClassOf &apos;negative regulation of killing of cells of another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902061</classIRI>
<classLabel>betaine aldehyde metabolic process</classLabel>
<deletedAxiom>&apos;betaine aldehyde metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;betaine aldehyde metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</newAxiom>
<newAxiom>&apos;betaine aldehyde metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902063</classIRI>
<classLabel>betaine aldehyde biosynthetic process</classLabel>
<deletedAxiom>&apos;betaine aldehyde biosynthetic process&apos; SubClassOf &apos;organonitrogen compound biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;betaine aldehyde biosynthetic process&apos; SubClassOf &apos;organic substance biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902062</classIRI>
<classLabel>betaine aldehyde catabolic process</classLabel>
<deletedAxiom>&apos;betaine aldehyde catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;betaine aldehyde catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902065</classIRI>
<classLabel>response to L-glutamate</classLabel>
<deletedAxiom>&apos;response to L-glutamate&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904809</classIRI>
<classLabel>regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;regulation of dense core granule transport&apos; SubClassOf &apos;regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of dense core granule transport&apos; SubClassOf &apos;regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904811</classIRI>
<classLabel>positive regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;positive regulation of dense core granule transport&apos; SubClassOf &apos;positive regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of dense core granule transport&apos; SubClassOf &apos;positive regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904810</classIRI>
<classLabel>negative regulation of dense core granule transport</classLabel>
<deletedAxiom>&apos;negative regulation of dense core granule transport&apos; SubClassOf &apos;negative regulation of cytoplasmic transport&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of dense core granule transport&apos; SubClassOf &apos;negative regulation of intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042956</classIRI>
<classLabel>maltodextrin transmembrane transport</classLabel>
<deletedAxiom>&apos;maltodextrin transmembrane transport&apos; SubClassOf &apos;polysaccharide transport&apos;</deletedAxiom>
<newAxiom>&apos;maltodextrin transmembrane transport&apos; SubClassOf &apos;dextrin transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042958</classIRI>
<classLabel>maltodextrin transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;maltodextrin transmembrane transporter activity&apos; SubClassOf &apos;polysaccharide transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;maltodextrin transmembrane transporter activity&apos; SubClassOf &apos;dextrin transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030960</classIRI>
<classLabel>peptide cross-linking via 3&apos;-(O4&apos;-L-tyrosinyl)-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(O4&apos;-L-tyrosinyl)-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(O4&apos;-L-tyrosinyl)-L-tyrosine&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015350</classIRI>
<classLabel>methotrexate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;methotrexate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;methotrexate transmembrane transporter activity&apos; SubClassOf &apos;modified amino acid transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042973</classIRI>
<classLabel>glucan endo-1,3-beta-D-glucosidase activity</classLabel>
<deletedAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity&apos; SubClassOf &apos;beta-glucosidase activity&apos;</deletedAxiom>
<newAxiom>&apos;glucan endo-1,3-beta-D-glucosidase activity&apos; SubClassOf &apos;glucosidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052344</classIRI>
<classLabel>positive regulation by symbiont of host phytoalexin production</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host phytoalexin production&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052390</classIRI>
<classLabel>induction by symbiont of host innate immune response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host innate immune response&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005905</classIRI>
<classLabel>clathrin-coated pit</classLabel>
<deletedAxiom>&apos;clathrin-coated pit&apos; SubClassOf &apos;plasma membrane region&apos;</deletedAxiom>
<newAxiom>&apos;clathrin-coated pit&apos; SubClassOf &apos;membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990887</classIRI>
<classLabel>2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity&apos; SubClassOf &apos;O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001196</classIRI>
<classLabel>positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine</classLabel>
<newAxiom>&apos;positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001159</classIRI>
<classLabel>regulation of protein localization by the Cvt pathway</classLabel>
<newAxiom>&apos;regulation of protein localization by the Cvt pathway&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
<newAxiom>&apos;regulation of protein localization by the Cvt pathway&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904960</classIRI>
<classLabel>positive regulation of cytochrome-c oxidase activity</classLabel>
<newAxiom>&apos;positive regulation of cytochrome-c oxidase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001168</classIRI>
<classLabel>positive regulation of histone H2B ubiquitination</classLabel>
<deletedAxiom>&apos;positive regulation of histone H2B ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H2B ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2B ubiquitination&apos; SubClassOf &apos;regulation of histone H2B ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2B ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H2B ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H2B ubiquitination&apos; SubClassOf &apos;positive regulation of histone ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001166</classIRI>
<classLabel>regulation of histone H2B ubiquitination</classLabel>
<deletedAxiom>&apos;regulation of histone H2B ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2B ubiquitination&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2B ubiquitination&apos; SubClassOf &apos;regulation of histone ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2B ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2B ubiquitination&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001173</classIRI>
<classLabel>regulation of histone H2B conserved C-terminal lysine ubiquitination</classLabel>
<deletedAxiom>&apos;regulation of histone H2B conserved C-terminal lysine ubiquitination&apos; SubClassOf &apos;regulation of histone H2B ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2B conserved C-terminal lysine ubiquitination&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2B conserved C-terminal lysine ubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H2B conserved C-terminal lysine ubiquitination&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H2B conserved C-terminal lysine ubiquitination&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030959</classIRI>
<classLabel>peptide cross-linking via 3&apos;-(3&apos;-L-tyrosinyl)-L-tyrosine</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(3&apos;-L-tyrosinyl)-L-tyrosine&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3&apos;-(3&apos;-L-tyrosinyl)-L-tyrosine&apos; SubClassOf &apos;peptidyl-tyrosine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904947</classIRI>
<classLabel>folate import into mitochondrion</classLabel>
<deletedAxiom>&apos;folate import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;folate import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001158</classIRI>
<classLabel>positive regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;positive regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;positive regulation of amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001157</classIRI>
<classLabel>negative regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;negative regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;negative regulation of amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001156</classIRI>
<classLabel>regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;regulation of amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904959</classIRI>
<classLabel>regulation of cytochrome-c oxidase activity</classLabel>
<newAxiom>&apos;regulation of cytochrome-c oxidase activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042925</classIRI>
<classLabel>benzoate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;benzoate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902221</classIRI>
<classLabel>erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process</classLabel>
<deletedAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170039</newAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015229</classIRI>
<classLabel>L-ascorbic acid transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-ascorbic acid transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902223</classIRI>
<classLabel>erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process</classLabel>
<deletedAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170038</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902222</classIRI>
<classLabel>erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process</classLabel>
<deletedAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
<newAxiom>&apos;erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170040</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015220</classIRI>
<classLabel>choline transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;choline transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;choline transmembrane transporter activity&apos; SubClassOf &apos;quaternary ammonium group transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;choline transmembrane transporter activity&apos; SubClassOf &apos;organic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042856</classIRI>
<classLabel>eugenol catabolic process</classLabel>
<newAxiom>&apos;eugenol catabolic process&apos; SubClassOf &apos;olefinic compound catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042855</classIRI>
<classLabel>eugenol biosynthetic process</classLabel>
<newAxiom>&apos;eugenol biosynthetic process&apos; SubClassOf &apos;olefinic compound biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042854</classIRI>
<classLabel>eugenol metabolic process</classLabel>
<newAxiom>&apos;eugenol metabolic process&apos; SubClassOf &apos;olefinic compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042853</classIRI>
<classLabel>L-alanine catabolic process</classLabel>
<newAxiom>&apos;L-alanine catabolic process&apos; SubClassOf &apos;pyruvate family amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042852</classIRI>
<classLabel>L-alanine biosynthetic process</classLabel>
<newAxiom>&apos;L-alanine biosynthetic process&apos; SubClassOf &apos;pyruvate family amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042851</classIRI>
<classLabel>L-alanine metabolic process</classLabel>
<newAxiom>&apos;L-alanine metabolic process&apos; SubClassOf &apos;pyruvate family amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990818</classIRI>
<classLabel>L-arginine transmembrane export from vacuole</classLabel>
<deletedAxiom>&apos;L-arginine transmembrane export from vacuole&apos; SubClassOf &apos;modified amino acid transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990983</classIRI>
<classLabel>tRNA demethylation</classLabel>
<deletedAxiom>&apos;tRNA demethylation&apos; SubClassOf &apos;oxidative RNA demethylation&apos;</deletedAxiom>
<newAxiom>&apos;tRNA demethylation&apos; SubClassOf &apos;regulation of translational initiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001080</classIRI>
<classLabel>chitosan binding</classLabel>
<newAxiom>&apos;chitosan binding&apos; SubClassOf &apos;cation binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005844</classIRI>
<classLabel>polysome</classLabel>
<deletedAxiom>&apos;polysome&apos; SubClassOf &apos;ribonucleoprotein complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005845</classIRI>
<classLabel>mRNA cap binding complex</classLabel>
<deletedAxiom>&apos;mRNA cap binding complex&apos; SubClassOf &apos;RNA cap binding complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902438</classIRI>
<classLabel>response to vanadate(3-)</classLabel>
<deletedAxiom>&apos;response to vanadate(3-)&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902439</classIRI>
<classLabel>cellular response to vanadate(3-)</classLabel>
<deletedAxiom>&apos;cellular response to vanadate(3-)&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015200</classIRI>
<classLabel>methylammonium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;methylammonium transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015217</classIRI>
<classLabel>ADP transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ADP transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015107</classIRI>
<classLabel>chlorate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;chlorate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015108</classIRI>
<classLabel>chloride transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;chloride transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015106</classIRI>
<classLabel>bicarbonate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;bicarbonate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;bicarbonate transmembrane transporter activity&apos; SubClassOf &apos;inorganic molecular entity transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902349</classIRI>
<classLabel>response to chloroquine</classLabel>
<deletedAxiom>&apos;response to chloroquine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015109</classIRI>
<classLabel>chromate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;chromate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902350</classIRI>
<classLabel>cellular response to chloroquine</classLabel>
<deletedAxiom>&apos;cellular response to chloroquine&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015116</classIRI>
<classLabel>sulfate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sulfate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015115</classIRI>
<classLabel>silicate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;silicate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015112</classIRI>
<classLabel>nitrate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;nitrate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015129</classIRI>
<classLabel>lactate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;lactate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904983</classIRI>
<classLabel>glycine import into mitochondrion</classLabel>
<deletedAxiom>&apos;glycine import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;glycine import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015123</classIRI>
<classLabel>acetate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;acetate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015138</classIRI>
<classLabel>fumarate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;fumarate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015137</classIRI>
<classLabel>citrate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;citrate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015130</classIRI>
<classLabel>mevalonate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;mevalonate transmembrane transporter activity&apos; SubClassOf &apos;organic hydroxy compound transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;mevalonate transmembrane transporter activity&apos; SubClassOf &apos;monocarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;mevalonate transmembrane transporter activity&apos; SubClassOf &apos;transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015141</classIRI>
<classLabel>succinate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;succinate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042744</classIRI>
<classLabel>hydrogen peroxide catabolic process</classLabel>
<deletedAxiom>&apos;hydrogen peroxide catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042743</classIRI>
<classLabel>hydrogen peroxide metabolic process</classLabel>
<deletedAxiom>&apos;hydrogen peroxide metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042784</classIRI>
<classLabel>evasion of host immune response via modulation of host complement system</classLabel>
<deletedAxiom>&apos;evasion of host immune response via modulation of host complement system&apos; SubClassOf &apos;evasion of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;evasion of host immune response via modulation of host complement system&apos; SubClassOf &apos;suppression of host innate immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015189</classIRI>
<classLabel>L-lysine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-lysine transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042788</classIRI>
<classLabel>polysomal ribosome</classLabel>
<deletedAxiom>&apos;polysomal ribosome&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;polysome&apos;</deletedAxiom>
<deletedAxiom>&apos;polysomal ribosome&apos; SubClassOf &apos;ribosome&apos;</deletedAxiom>
<deletedAxiom>&apos;polysomal ribosome&apos; EquivalentTo &apos;ribosome&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;polysome&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042786</classIRI>
<classLabel>evasion of host immune response via modulation of host antigen processing and presentation</classLabel>
<deletedAxiom>&apos;evasion of host immune response via modulation of host antigen processing and presentation&apos; SubClassOf &apos;evasion of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042785</classIRI>
<classLabel>evasion of host immune response via modulation of host cytokine network</classLabel>
<deletedAxiom>&apos;evasion of host immune response via modulation of host cytokine network&apos; SubClassOf &apos;evasion of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052103</classIRI>
<classLabel>induction of host induced systemic resistance</classLabel>
<deletedAxiom>&apos;induction of host induced systemic resistance&apos; SubClassOf &apos;induction by symbiont of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052102</classIRI>
<classLabel>positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052104</classIRI>
<classLabel>induction by symbiont of host systemic acquired resistance</classLabel>
<deletedAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;perturbation of host systemic acquired resistance&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by symbiont of host systemic acquired resistance&apos; SubClassOf &apos;induction by symbiont of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052148</classIRI>
<classLabel>modulation by symbiont of host catalytic activity</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host catalytic activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host catalytic activity&apos; SubClassOf &apos;modulation by symbiont of host molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host catalytic activity&apos; EquivalentTo &apos;modulation by symbiont of host molecular function&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;catalytic activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052078</classIRI>
<classLabel>symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;suppression of host defenses by symbiont&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host receptor-mediated signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052075</classIRI>
<classLabel>induction by symbiont of host jasmonic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;induction by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by symbiont of host jasmonic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052074</classIRI>
<classLabel>positive regulation by symbiont of host salicylic acid-mediated defense response</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;systemic acquired resistance, salicylic acid mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;positive regulation of systemic acquired resistance&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;positive regulation of signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation by symbiont of host salicylic acid-mediated defense response&apos; SubClassOf &apos;modulation by symbiont of host salicylic acid-mediated defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902465</classIRI>
<classLabel>negative regulation of histone H3-K27 trimethylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K27 trimethylation&apos; SubClassOf &apos;negative regulation of histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K27 trimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K27 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K27 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K27 trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902464</classIRI>
<classLabel>regulation of histone H3-K27 trimethylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K27 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K27 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K27 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K27 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K27 trimethylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902466</classIRI>
<classLabel>positive regulation of histone H3-K27 trimethylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K27 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K27 trimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K27 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 trimethylation&apos; SubClassOf &apos;positive regulation of histone H3-K27 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K27 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K27 trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902444</classIRI>
<classLabel>riboflavin binding</classLabel>
<newAxiom>&apos;riboflavin binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902485</classIRI>
<classLabel>L-cysteine binding</classLabel>
<deletedAxiom>&apos;L-cysteine binding&apos; SubClassOf &apos;modified amino acid binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052009</classIRI>
<classLabel>symbiont-mediated disruption of host cell wall</classLabel>
<deletedAxiom>&apos;symbiont-mediated disruption of host cell wall&apos; SubClassOf &apos;symbiont-mediated disruption of host cellular anatomical entity&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated disruption of host cell wall&apos; SubClassOf &apos;symbiont-mediated disruption of host cell envelope&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052003</classIRI>
<classLabel>symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052019</classIRI>
<classLabel>modulation by symbiont of host hormone or growth regulator levels</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host hormone or growth regulator levels&apos; SubClassOf &apos;modulation by symbiont of host process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015079</classIRI>
<classLabel>potassium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;potassium ion transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052022</classIRI>
<classLabel>modulation by symbiont of jasmonic acid levels in host</classLabel>
<deletedAxiom>&apos;modulation by symbiont of jasmonic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052021</classIRI>
<classLabel>modulation by symbiont of ethylene levels in host</classLabel>
<deletedAxiom>&apos;modulation by symbiont of ethylene levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052024</classIRI>
<classLabel>positive regulation by symbiont of hormone or growth regulator levels in host</classLabel>
<deletedAxiom>&apos;positive regulation by symbiont of hormone or growth regulator levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052023</classIRI>
<classLabel>modulation by symbiont of salicylic acid levels in host</classLabel>
<deletedAxiom>&apos;modulation by symbiont of salicylic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of host hormone or growth regulator levels&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015081</classIRI>
<classLabel>sodium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sodium ion transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015085</classIRI>
<classLabel>calcium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;calcium ion transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015091</classIRI>
<classLabel>ferric iron transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ferric iron transmembrane transporter activity&apos; SubClassOf &apos;sulfur compound transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ferric iron transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015098</classIRI>
<classLabel>molybdate ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;molybdate ion transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052055</classIRI>
<classLabel>modulation by symbiont of host molecular function</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host molecular function&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;molecular_function&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host molecular function&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;molecular_function&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host molecular function&apos; SubClassOf &apos;modulation by symbiont of host process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052053</classIRI>
<classLabel>negative regulation by symbiont of host catalytic activity</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host catalytic activity&apos; EquivalentTo &apos;modulation by symbiont of host molecular function&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;catalytic activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host catalytic activity&apos; SubClassOf &apos;modulation by symbiont of host catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host catalytic activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052062</classIRI>
<classLabel>induction by symbiont of host phytoalexin production</classLabel>
<deletedAxiom>&apos;induction by symbiont of host phytoalexin production&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052064</classIRI>
<classLabel>induction by symbiont of defense-related host reactive oxygen species production</classLabel>
<deletedAxiom>&apos;induction by symbiont of defense-related host reactive oxygen species production&apos; SubClassOf &apos;induction by symbiont of host immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052026</classIRI>
<classLabel>modulation by symbiont of host transcription</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host transcription&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host transcription&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052027</classIRI>
<classLabel>perturbation of host signal transduction pathway</classLabel>
<deletedAxiom>&apos;perturbation of host signal transduction pathway&apos; SubClassOf &apos;perturbation of signal transduction in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902621</classIRI>
<classLabel>actomyosin contractile ring disassembly</classLabel>
<deletedAxiom>&apos;actomyosin contractile ring disassembly&apos; SubClassOf &apos;cytokinetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;actomyosin contractile ring disassembly&apos; SubClassOf &apos;actomyosin contractile ring organization&apos;</deletedAxiom>
<deletedAxiom>&apos;actomyosin contractile ring disassembly&apos; SubClassOf &apos;cellular component disassembly&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902618</classIRI>
<classLabel>cellular response to fluoride</classLabel>
<deletedAxiom>&apos;cellular response to fluoride&apos; SubClassOf &apos;cellular response to salt&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular response to fluoride&apos; SubClassOf &apos;cellular response to oxygen-containing compound&apos;</deletedAxiom>
<newAxiom>&apos;cellular response to fluoride&apos; SubClassOf &apos;cellular response to chemical stimulus&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902617</classIRI>
<classLabel>response to fluoride</classLabel>
<deletedAxiom>&apos;response to fluoride&apos; SubClassOf &apos;response to oxygen-containing compound&apos;</deletedAxiom>
<deletedAxiom>&apos;response to fluoride&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902670</classIRI>
<classLabel>carbon dioxide binding</classLabel>
<deletedAxiom>&apos;carbon dioxide binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;carbon dioxide binding&apos; SubClassOf &apos;small molecule binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001297</classIRI>
<classLabel>N(omega)-methyl-L-arginine catabolic process</classLabel>
<deletedAxiom>&apos;N(omega)-methyl-L-arginine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;N(omega)-methyl-L-arginine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N(omega)-methyl-L-arginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
<newAxiom>&apos;N(omega)-methyl-L-arginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001296</classIRI>
<classLabel>N(omega)-methyl-L-arginine metabolic process</classLabel>
<deletedAxiom>&apos;N(omega)-methyl-L-arginine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N(omega)-methyl-L-arginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;N(omega)-methyl-L-arginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001299</classIRI>
<classLabel>N(omega),N(omega)-dimethyl-L-arginine catabolic process</classLabel>
<deletedAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001298</classIRI>
<classLabel>N(omega),N(omega)-dimethyl-L-arginine metabolic process</classLabel>
<deletedAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
<newAxiom>&apos;N(omega),N(omega)-dimethyl-L-arginine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001278</classIRI>
<classLabel>positive regulation of leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of leucine biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of leucine biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of leucine biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;positive regulation of leucine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001277</classIRI>
<classLabel>negative regulation of leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of leucine biosynthetic process&apos; SubClassOf &apos;negative regulation of amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of leucine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of leucine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;negative regulation of leucine biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001276</classIRI>
<classLabel>regulation of leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of leucine biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of leucine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</newAxiom>
<newAxiom>&apos;regulation of leucine biosynthetic process&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042542</classIRI>
<classLabel>response to hydrogen peroxide</classLabel>
<deletedAxiom>&apos;response to hydrogen peroxide&apos; SubClassOf &apos;response to organic substance&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030580</classIRI>
<classLabel>quinone cofactor methyltransferase activity</classLabel>
<deletedAxiom>&apos;quinone cofactor methyltransferase activity&apos; SubClassOf &apos;C-methyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;quinone cofactor methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140933</classIRI>
<classLabel>5&apos;-(N(7)-methylguanosine 5&apos;-triphospho)-[mRNA] hydrolase activity</classLabel>
<deletedAxiom>&apos;5&apos;-(N(7)-methylguanosine 5&apos;-triphospho)-[mRNA] hydrolase activity&apos; SubClassOf &apos;mRNA 5&apos;-phosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;5&apos;-(N(7)-methylguanosine 5&apos;-triphospho)-[mRNA] hydrolase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140932</classIRI>
<classLabel>5&apos;-(N(7)-methyl 5&apos;-triphosphoguanosine)-[mRNA] diphosphatase activity</classLabel>
<deletedAxiom>&apos;5&apos;-(N(7)-methyl 5&apos;-triphosphoguanosine)-[mRNA] diphosphatase activity&apos; SubClassOf &apos;mRNA 5&apos;-diphosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;5&apos;-(N(7)-methyl 5&apos;-triphosphoguanosine)-[mRNA] diphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140917</classIRI>
<classLabel>zinc ion import into mitochondrion</classLabel>
<deletedAxiom>&apos;zinc ion import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;zinc ion import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900109</classIRI>
<classLabel>regulation of histone H3-K9 dimethylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K9 dimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 dimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 dimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 dimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 dimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900110</classIRI>
<classLabel>negative regulation of histone H3-K9 dimethylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K9 dimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 dimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 dimethylation&apos; SubClassOf &apos;negative regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 dimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 dimethylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900111</classIRI>
<classLabel>positive regulation of histone H3-K9 dimethylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K9 dimethylation&apos; SubClassOf &apos;positive regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 dimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 dimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 dimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 dimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 dimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900112</classIRI>
<classLabel>regulation of histone H3-K9 trimethylation</classLabel>
<deletedAxiom>&apos;regulation of histone H3-K9 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 trimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of histone H3-K9 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone H3-K9 trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900113</classIRI>
<classLabel>negative regulation of histone H3-K9 trimethylation</classLabel>
<deletedAxiom>&apos;negative regulation of histone H3-K9 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 trimethylation&apos; SubClassOf &apos;negative regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of histone H3-K9 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone H3-K9 trimethylation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900114</classIRI>
<classLabel>positive regulation of histone H3-K9 trimethylation</classLabel>
<deletedAxiom>&apos;positive regulation of histone H3-K9 trimethylation&apos; SubClassOf &apos;regulation of histone H3-K9 trimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 trimethylation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 trimethylation&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 trimethylation&apos; SubClassOf &apos;positive regulation of histone H3-K9 methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of histone H3-K9 trimethylation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;histone H3-K9 trimethylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900080</classIRI>
<classLabel>positive regulation of arginine biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of arginine biosynthetic process&apos; SubClassOf &apos;positive regulation of amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900081</classIRI>
<classLabel>regulation of arginine catabolic process</classLabel>
<newAxiom>&apos;regulation of arginine catabolic process&apos; SubClassOf &apos;regulation of glutamine family amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900082</classIRI>
<classLabel>negative regulation of arginine catabolic process</classLabel>
<newAxiom>&apos;negative regulation of arginine catabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030417</classIRI>
<classLabel>nicotianamine metabolic process</classLabel>
<newAxiom>&apos;nicotianamine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030433</classIRI>
<classLabel>ubiquitin-dependent ERAD pathway</classLabel>
<deletedAxiom>&apos;ubiquitin-dependent ERAD pathway&apos; SubClassOf &apos;ERAD pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;ubiquitin-dependent ERAD pathway&apos; SubClassOf &apos;proteasome-mediated ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042418</classIRI>
<classLabel>epinephrine biosynthetic process</classLabel>
<deletedAxiom>&apos;epinephrine biosynthetic process&apos; SubClassOf &apos;catecholamine biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042414</classIRI>
<classLabel>epinephrine metabolic process</classLabel>
<deletedAxiom>&apos;epinephrine metabolic process&apos; SubClassOf &apos;catecholamine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042419</classIRI>
<classLabel>epinephrine catabolic process</classLabel>
<deletedAxiom>&apos;epinephrine catabolic process&apos; SubClassOf &apos;catecholamine catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;epinephrine catabolic process&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900079</classIRI>
<classLabel>regulation of arginine biosynthetic process</classLabel>
<newAxiom>&apos;regulation of arginine biosynthetic process&apos; SubClassOf &apos;regulation of glutamine family amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140886</classIRI>
<classLabel>suppression by virus of host interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host interferon-mediated signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140885</classIRI>
<classLabel>suppression by virus of host type III interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;type III interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;type III interferon-mediated signaling pathway&apos;)</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type III interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140884</classIRI>
<classLabel>suppression by virus of host type II interferon-mediated signaling pathway</classLabel>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; EquivalentTo &apos;modulation by virus of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;type II interferon-mediated signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;type II interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression of host interferon-mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;suppression by virus of host type II interferon-mediated signaling pathway&apos; SubClassOf &apos;suppression by virus of host interferon-mediated signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140812</classIRI>
<classLabel>orotate:monoatomic anion antiporter activity</classLabel>
<deletedAxiom>&apos;orotate:monoatomic anion antiporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005302</classIRI>
<classLabel>L-tyrosine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-tyrosine transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900177</classIRI>
<classLabel>regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900178</classIRI>
<classLabel>negative regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900179</classIRI>
<classLabel>positive regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005313</classIRI>
<classLabel>L-glutamate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;L-glutamate transmembrane transporter activity&apos; SubClassOf &apos;amide transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-glutamate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005347</classIRI>
<classLabel>ATP transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;ATP transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005372</classIRI>
<classLabel>water transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;water transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005385</classIRI>
<classLabel>zinc ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;zinc ion transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030393</classIRI>
<classLabel>fructoselysine metabolic process</classLabel>
<deletedAxiom>&apos;fructoselysine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;fructoselysine metabolic process&apos; SubClassOf &apos;carboxylic acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;fructoselysine metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902986</classIRI>
<classLabel>regulation of lysine biosynthetic process via aminoadipic acid</classLabel>
<newAxiom>&apos;regulation of lysine biosynthetic process via aminoadipic acid&apos; SubClassOf &apos;regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902987</classIRI>
<classLabel>negative regulation of lysine biosynthetic process via aminoadipic acid</classLabel>
<newAxiom>&apos;negative regulation of lysine biosynthetic process via aminoadipic acid&apos; SubClassOf &apos;negative regulation of cellular amino acid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900339</classIRI>
<classLabel>regulation of methane biosynthetic process from formic acid</classLabel>
<deletedAxiom>&apos;regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019926</classIRI>
<classLabel>peptidyl-tryptophan oxidation to tryptophyl quinone</classLabel>
<deletedAxiom>&apos;peptidyl-tryptophan oxidation to tryptophyl quinone&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;peptide cross-linking via 4&apos;-(L-tryptophan)-L-tryptophyl quinone&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-tryptophan oxidation to tryptophyl quinone&apos; SubClassOf &apos;peptidyl-tryptophan modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptidyl-tryptophan oxidation to tryptophyl quinone&apos; SubClassOf &apos;protein oxidation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900340</classIRI>
<classLabel>negative regulation of methane biosynthetic process from formic acid</classLabel>
<deletedAxiom>&apos;negative regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;negative regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900341</classIRI>
<classLabel>positive regulation of methane biosynthetic process from formic acid</classLabel>
<deletedAxiom>&apos;positive regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;positive regulation of nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019932</classIRI>
<classLabel>second-messenger-mediated signaling</classLabel>
<deletedAxiom>&apos;second-messenger-mediated signaling&apos; SubClassOf &apos;intracellular signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019935</classIRI>
<classLabel>cyclic-nucleotide-mediated signaling</classLabel>
<deletedAxiom>&apos;cyclic-nucleotide-mediated signaling&apos; SubClassOf &apos;second-messenger-mediated signaling&apos;</deletedAxiom>
<newAxiom>&apos;cyclic-nucleotide-mediated signaling&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019927</classIRI>
<classLabel>peptide cross-linking via 4&apos;-(S-L-cysteinyl)-L-tryptophyl quinone</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 4&apos;-(S-L-cysteinyl)-L-tryptophyl quinone&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 4&apos;-(S-L-cysteinyl)-L-tryptophyl quinone&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019928</classIRI>
<classLabel>peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid&apos; SubClassOf &apos;peptidyl-aspartic acid modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019929</classIRI>
<classLabel>peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid</classLabel>
<deletedAxiom>&apos;peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid&apos; SubClassOf &apos;peptidyl-cysteine modification&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid&apos; SubClassOf &apos;peptidyl-glutamic acid modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032811</classIRI>
<classLabel>negative regulation of epinephrine secretion</classLabel>
<deletedAxiom>&apos;negative regulation of epinephrine secretion&apos; SubClassOf &apos;negative regulation of catecholamine secretion&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of epinephrine secretion&apos; SubClassOf &apos;negative regulation of secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032812</classIRI>
<classLabel>positive regulation of epinephrine secretion</classLabel>
<deletedAxiom>&apos;positive regulation of epinephrine secretion&apos; SubClassOf &apos;positive regulation of catecholamine secretion&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of epinephrine secretion&apos; SubClassOf &apos;positive regulation of secretion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019872</classIRI>
<classLabel>streptomycin biosynthetic process</classLabel>
<deletedAxiom>&apos;streptomycin biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044831</classIRI>
<classLabel>modulation by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf &apos;modulation by virus of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044832</classIRI>
<classLabel>induction by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; SubClassOf &apos;positive regulation of cytokine production&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; SubClassOf &apos;induction by symbiont of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; SubClassOf &apos;modulation by virus of host cytokine production&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host cytokine production&apos; EquivalentTo &apos;perturbation by virus of host immune response&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cytokine production&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044863</classIRI>
<classLabel>modulation by virus of host cell division</classLabel>
<newAxiom>&apos;modulation by virus of host cell division&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030209</classIRI>
<classLabel>dermatan sulfate catabolic process</classLabel>
<deletedAxiom>&apos;dermatan sulfate catabolic process&apos; SubClassOf &apos;monosaccharide catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dermatan sulfate catabolic process&apos; SubClassOf &apos;amino disaccharide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140655</classIRI>
<classLabel>mitochondrial proliferation</classLabel>
<deletedAxiom>&apos;mitochondrial proliferation&apos; SubClassOf &apos;mitochondrion organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030205</classIRI>
<classLabel>dermatan sulfate metabolic process</classLabel>
<deletedAxiom>&apos;dermatan sulfate metabolic process&apos; SubClassOf &apos;monosaccharide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;dermatan sulfate metabolic process&apos; SubClassOf &apos;amino disaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030208</classIRI>
<classLabel>dermatan sulfate biosynthetic process</classLabel>
<deletedAxiom>&apos;dermatan sulfate biosynthetic process&apos; SubClassOf &apos;monosaccharide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005277</classIRI>
<classLabel>acetylcholine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;acetylcholine transmembrane transporter activity&apos; SubClassOf &apos;quaternary ammonium group transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;acetylcholine transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;acetylcholine transmembrane transporter activity&apos; SubClassOf &apos;organic cation transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044846</classIRI>
<classLabel>negative regulation by symbiont of indole acetic acid levels in host</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of indole acetic acid levels in host&apos; SubClassOf &apos;modulation by symbiont of indole acetic acid levels in host&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042220</classIRI>
<classLabel>response to cocaine</classLabel>
<deletedAxiom>&apos;response to cocaine&apos; SubClassOf &apos;response to salt&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042218</classIRI>
<classLabel>1-aminocyclopropane-1-carboxylate biosynthetic process</classLabel>
<newAxiom>&apos;1-aminocyclopropane-1-carboxylate biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;1-aminocyclopropane-1-carboxylate biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042217</classIRI>
<classLabel>1-aminocyclopropane-1-carboxylate catabolic process</classLabel>
<newAxiom>&apos;1-aminocyclopropane-1-carboxylate catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140636</classIRI>
<classLabel>copper import into the mitochondrion</classLabel>
<deletedAxiom>&apos;copper import into the mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;copper import into the mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900483</classIRI>
<classLabel>regulation of protein targeting to vacuolar membrane</classLabel>
<newAxiom>&apos;regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;regulation of intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900484</classIRI>
<classLabel>negative regulation of protein targeting to vacuolar membrane</classLabel>
<newAxiom>&apos;negative regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;negative regulation of vacuolar transport&apos;</newAxiom>
<newAxiom>&apos;negative regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;negative regulation of intracellular protein transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900485</classIRI>
<classLabel>positive regulation of protein targeting to vacuolar membrane</classLabel>
<newAxiom>&apos;positive regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;positive regulation of intracellular protein transport&apos;</newAxiom>
<newAxiom>&apos;positive regulation of protein targeting to vacuolar membrane&apos; SubClassOf &apos;positive regulation of vacuolar transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019800</classIRI>
<classLabel>peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan</classLabel>
<deletedAxiom>&apos;peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan&apos; SubClassOf &apos;chondroitin sulfate metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan&apos; SubClassOf &apos;peptide cross-linking&apos;</deletedAxiom>
<deletedAxiom>&apos;peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan&apos; SubClassOf &apos;peptidyl-serine modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019811</classIRI>
<classLabel>cocaine binding</classLabel>
<newAxiom>&apos;cocaine binding&apos; SubClassOf &apos;heterocyclic compound binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019808</classIRI>
<classLabel>polyamine binding</classLabel>
<deletedAxiom>&apos;polyamine binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;polyamine binding&apos; SubClassOf &apos;amine binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019722</classIRI>
<classLabel>calcium-mediated signaling</classLabel>
<deletedAxiom>&apos;calcium-mediated signaling&apos; SubClassOf &apos;second-messenger-mediated signaling&apos;</deletedAxiom>
<newAxiom>&apos;calcium-mediated signaling&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141124</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019730</classIRI>
<classLabel>antimicrobial humoral response</classLabel>
<deletedAxiom>&apos;antimicrobial humoral response&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;antimicrobial humoral response&apos; SubClassOf &apos;defense response to symbiont&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019749</classIRI>
<classLabel>cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte</classLabel>
<deletedAxiom>&apos;cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte&apos; EquivalentTo &apos;cytoplasmic transport, nurse cell to oocyte&apos; and &apos;cytoskeleton-dependent intracellular transport&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte&apos; SubClassOf &apos;cytoplasmic transport, nurse cell to oocyte&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044736</classIRI>
<classLabel>acid-sensing ion channel activity</classLabel>
<deletedAxiom>&apos;acid-sensing ion channel activity&apos; SubClassOf &apos;ligand-gated monoatomic ion channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140532</classIRI>
<classLabel>negative regulation of osmosensory signaling MAPK cascade</classLabel>
<deletedAxiom>&apos;negative regulation of osmosensory signaling MAPK cascade&apos; SubClassOf &apos;negative regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling MAPK cascade&apos; SubClassOf &apos;regulation of osmosensory signaling MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling MAPK cascade&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;osmosensory signaling MAPK cascade&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;osmosensory signaling MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of osmosensory signaling MAPK cascade&apos; SubClassOf &apos;negative regulation of osmosensory signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140531</classIRI>
<classLabel>regulation of osmosensory signaling MAPK cascade</classLabel>
<deletedAxiom>&apos;regulation of osmosensory signaling MAPK cascade&apos; SubClassOf &apos;regulation of osmosensory signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling MAPK cascade&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;osmosensory signaling MAPK cascade&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;osmosensory signaling MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of osmosensory signaling MAPK cascade&apos; SubClassOf &apos;regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044758</classIRI>
<classLabel>modulation by symbiont of host synaptic transmission</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host synaptic transmission&apos; EquivalentTo &apos;modulation by symbiont of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
<newAxiom>&apos;modulation by symbiont of host synaptic transmission&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chemical synaptic transmission&apos;)</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030150</classIRI>
<classLabel>protein import into mitochondrial matrix</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044694</classIRI>
<classLabel>pore-mediated entry of viral genome into host cell</classLabel>
<deletedAxiom>&apos;pore-mediated entry of viral genome into host cell&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;virus-mediated pore formation in host cell membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;pore-mediated entry of viral genome into host cell&apos; SubClassOf &apos;transport of virus&apos;</deletedAxiom>
<deletedAxiom>&apos;pore-mediated entry of viral genome into host cell&apos; SubClassOf &apos;viral entry into host cell&apos;</deletedAxiom>
<newAxiom>&apos;pore-mediated entry of viral genome into host cell&apos; SubClassOf &apos;symbiont-mediated disruption of host cellular anatomical entity&apos;</newAxiom>
<newAxiom>&apos;pore-mediated entry of viral genome into host cell&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140485</classIRI>
<classLabel>5-aminolevulinic acid transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;5-aminolevulinic acid transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140466</classIRI>
<classLabel>iron-sulfur cluster export from the mitochondrion</classLabel>
<deletedAxiom>&apos;iron-sulfur cluster export from the mitochondrion&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;iron-sulfur cluster export from the mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019651</classIRI>
<classLabel>citrate catabolic process to diacetyl</classLabel>
<deletedAxiom>&apos;citrate catabolic process to diacetyl&apos; SubClassOf &apos;nitrogenous compound fermentation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019654</classIRI>
<classLabel>acetate fermentation</classLabel>
<deletedAxiom>&apos;acetate fermentation&apos; SubClassOf &apos;nitrogenous compound fermentation&apos;</deletedAxiom>
<newAxiom>&apos;acetate fermentation&apos; SubClassOf &apos;fermentation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044604</classIRI>
<classLabel>ABC-type phytochelatin transporter activity</classLabel>
<newAxiom>&apos;ABC-type phytochelatin transporter activity&apos; SubClassOf &apos;organic anion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044640</classIRI>
<classLabel>envenomation resulting in negative regulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, lectin pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;negative regulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044641</classIRI>
<classLabel>envenomation resulting in positive regulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, lectin pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044642</classIRI>
<classLabel>envenomation resulting in modulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, alternative pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044643</classIRI>
<classLabel>envenomation resulting in positive regulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, alternative pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044633</classIRI>
<classLabel>modulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;modulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;modulation of complement activation in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;regulation of complement activation, alternative pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044634</classIRI>
<classLabel>negative regulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;negative regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;negative regulation of complement activation, alternative pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044635</classIRI>
<classLabel>positive regulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;positive regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;positive regulation of complement activation, alternative pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044636</classIRI>
<classLabel>envenomation resulting in modulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, classical pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044637</classIRI>
<classLabel>envenomation resulting in negative regulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, classical pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;negative regulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044638</classIRI>
<classLabel>envenomation resulting in positive regulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in positive regulation of complement activation, classical pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;positive regulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044639</classIRI>
<classLabel>envenomation resulting in modulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation, lectin pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019695</classIRI>
<classLabel>choline metabolic process</classLabel>
<deletedAxiom>&apos;choline metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;choline metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044630</classIRI>
<classLabel>modulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;modulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;modulation of complement activation in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;regulation of complement activation, lectin pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044631</classIRI>
<classLabel>positive regulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;positive regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;positive regulation of complement activation, lectin pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044632</classIRI>
<classLabel>negative regulation of complement activation, lectin pathway in another organism</classLabel>
<deletedAxiom>&apos;negative regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;negative regulation of complement activation, lectin pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of complement activation, lectin pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, lectin pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044627</classIRI>
<classLabel>modulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;modulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;modulation of complement activation in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;regulation of complement activation, classical pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044628</classIRI>
<classLabel>positive regulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;positive regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;positive regulation of complement activation, classical pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044629</classIRI>
<classLabel>negative regulation of complement activation, classical pathway in another organism</classLabel>
<deletedAxiom>&apos;negative regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;negative regulation of complement activation, classical pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of complement activation, classical pathway in another organism&apos; SubClassOf &apos;modulation of complement activation, classical pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005078</classIRI>
<classLabel>MAP-kinase scaffold activity</classLabel>
<deletedAxiom>&apos;MAP-kinase scaffold activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;MAP-kinase scaffold activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044644</classIRI>
<classLabel>envenomation resulting in negative regulation of complement activation, alternative pathway in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, alternative pathway in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;negative regulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in negative regulation of complement activation, alternative pathway in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of complement activation, alternative pathway in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044645</classIRI>
<classLabel>modulation of complement activation in another organism</classLabel>
<deletedAxiom>&apos;modulation of complement activation in another organism&apos; SubClassOf &apos;modulation of process of another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation of complement activation in another organism&apos; SubClassOf &apos;regulation of innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044646</classIRI>
<classLabel>envenomation resulting in modulation of complement activation in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of process in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of complement activation in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of complement activation in another organism&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044648</classIRI>
<classLabel>histone H3-K4 dimethylation</classLabel>
<deletedAxiom>&apos;histone H3-K4 dimethylation&apos; SubClassOf &apos;peptidyl-lysine dimethylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone H3-K4 dimethylation&apos; SubClassOf &apos;histone H3-K4 methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044595</classIRI>
<classLabel>decaprenyldihydroxybenzoate methyltransferase activity</classLabel>
<deletedAxiom>&apos;decaprenyldihydroxybenzoate methyltransferase activity&apos; SubClassOf &apos;3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044596</classIRI>
<classLabel>3-demethylubiquinol-10 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-demethylubiquinol-10 3-O-methyltransferase activity&apos; SubClassOf &apos;3-demethylubiquinol-n 3-O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044590</classIRI>
<classLabel>iron-sulfur-molybdenum cofactor binding</classLabel>
<deletedAxiom>&apos;iron-sulfur-molybdenum cofactor binding&apos; SubClassOf &apos;binding&apos;</deletedAxiom>
<newAxiom>&apos;iron-sulfur-molybdenum cofactor binding&apos; SubClassOf &apos;iron-sulfur cluster binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140361</classIRI>
<classLabel>cyclic-GMP-AMP transmembrane import across plasma membrane</classLabel>
<deletedAxiom>&apos;cyclic-GMP-AMP transmembrane import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019500</classIRI>
<classLabel>cyanide catabolic process</classLabel>
<deletedAxiom>&apos;cyanide catabolic process&apos; SubClassOf &apos;organonitrogen compound catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cyanide catabolic process&apos; SubClassOf &apos;organic substance catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019502</classIRI>
<classLabel>L-proline betaine metabolic process</classLabel>
<deletedAxiom>&apos;L-proline betaine metabolic process&apos; SubClassOf &apos;alpha-amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-proline betaine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
<newAxiom>&apos;L-proline betaine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170033</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019503</classIRI>
<classLabel>L-proline betaine biosynthetic process</classLabel>
<deletedAxiom>&apos;L-proline betaine biosynthetic process&apos; SubClassOf &apos;alpha-amino acid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-proline betaine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170034</newAxiom>
<newAxiom>&apos;L-proline betaine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019504</classIRI>
<classLabel>L-proline betaine catabolic process</classLabel>
<deletedAxiom>&apos;L-proline betaine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;L-proline betaine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-proline betaine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;L-proline betaine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019510</classIRI>
<classLabel>S-adenosylhomocysteine catabolic process</classLabel>
<deletedAxiom>&apos;S-adenosylhomocysteine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;S-adenosylhomocysteine catabolic process&apos; SubClassOf &apos;amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;S-adenosylhomocysteine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
<newAxiom>&apos;S-adenosylhomocysteine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170035</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019521</classIRI>
<classLabel>D-gluconate metabolic process</classLabel>
<deletedAxiom>&apos;D-gluconate metabolic process&apos; SubClassOf &apos;oligosaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019531</classIRI>
<classLabel>oxalate transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;oxalate transmembrane transporter activity&apos; SubClassOf &apos;salt transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019532</classIRI>
<classLabel>oxalate transport</classLabel>
<deletedAxiom>&apos;oxalate transport&apos; SubClassOf &apos;nitrogen compound transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140321</classIRI>
<classLabel>symbiont-mediated suppression of host autophagy</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; EquivalentTo &apos;modulation by symbiont of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;autophagy&apos;)</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf &apos;modulation by symbiont of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019541</classIRI>
<classLabel>propionate metabolic process</classLabel>
<deletedAxiom>&apos;propionate metabolic process&apos; SubClassOf &apos;nitrogen compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019544</classIRI>
<classLabel>arginine catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;arginine catabolic process to glutamate&apos; SubClassOf &apos;amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140300</classIRI>
<classLabel>serine import into mitochondrion</classLabel>
<deletedAxiom>&apos;serine import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;serine import into mitochondrion&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170036</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019557</classIRI>
<classLabel>histidine catabolic process to glutamate and formate</classLabel>
<deletedAxiom>&apos;histidine catabolic process to glutamate and formate&apos; SubClassOf &apos;amide catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032500</classIRI>
<classLabel>muramyl dipeptide binding</classLabel>
<newAxiom>&apos;muramyl dipeptide binding&apos; SubClassOf &apos;monocarboxylic acid binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044534</classIRI>
<classLabel>envenomation resulting in modulation of apoptotic process in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in modulation of apoptotic process in another organism&apos; SubClassOf &apos;envenomation resulting in modulation of process in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of apoptotic process in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of apoptotic process in another organism&apos;</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in modulation of apoptotic process in another organism&apos; EquivalentTo &apos;envenomation resulting in modulation of process in another organism&apos; and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;modulation of apoptotic process in another organism&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044523</classIRI>
<classLabel>envenomation resulting in damage of muscle extracellular matrix in another organism</classLabel>
<newAxiom>&apos;envenomation resulting in damage of muscle extracellular matrix in another organism&apos; SubClassOf &apos;disruption of extracellular matrix of another organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044466</classIRI>
<classLabel>glutaryl-CoA hydrolase activity</classLabel>
<deletedAxiom>&apos;glutaryl-CoA hydrolase activity&apos; SubClassOf &apos;acyl-CoA hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032482</classIRI>
<classLabel>Rab protein signal transduction</classLabel>
<deletedAxiom>&apos;Rab protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Rab protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032484</classIRI>
<classLabel>Ral protein signal transduction</classLabel>
<deletedAxiom>&apos;Ral protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Ral protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032483</classIRI>
<classLabel>regulation of Rab protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Rab protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of Rab protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032486</classIRI>
<classLabel>Rap protein signal transduction</classLabel>
<deletedAxiom>&apos;Rap protein signal transduction&apos; SubClassOf &apos;Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;Rap protein signal transduction&apos; SubClassOf &apos;small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032485</classIRI>
<classLabel>regulation of Ral protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Ral protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of Ral protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032487</classIRI>
<classLabel>regulation of Rap protein signal transduction</classLabel>
<deletedAxiom>&apos;regulation of Rap protein signal transduction&apos; SubClassOf &apos;regulation of Ras protein signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;regulation of Rap protein signal transduction&apos; SubClassOf &apos;regulation of small GTPase mediated signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900744</classIRI>
<classLabel>regulation of p38MAPK cascade</classLabel>
<deletedAxiom>&apos;regulation of p38MAPK cascade&apos; SubClassOf &apos;regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;regulation of p38MAPK cascade&apos; SubClassOf &apos;regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900745</classIRI>
<classLabel>positive regulation of p38MAPK cascade</classLabel>
<deletedAxiom>&apos;positive regulation of p38MAPK cascade&apos; SubClassOf &apos;positive regulation of stress-activated MAPK cascade&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of p38MAPK cascade&apos; SubClassOf &apos;positive regulation of MAPK cascade&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140267</classIRI>
<classLabel>viral entry via permeabilization of host membrane</classLabel>
<deletedAxiom>&apos;viral entry via permeabilization of host membrane&apos; SubClassOf &apos;viral entry into host cell&apos;</deletedAxiom>
<newAxiom>&apos;viral entry via permeabilization of host membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;viral entry into host cell&apos;</newAxiom>
<newAxiom>&apos;viral entry via permeabilization of host membrane&apos; SubClassOf &apos;symbiont-mediated disruption of host cellular anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140270</classIRI>
<classLabel>gluconate import across plasma membrane</classLabel>
<deletedAxiom>&apos;gluconate import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140204</classIRI>
<classLabel>pyridoxal import across plasma membrane</classLabel>
<deletedAxiom>&apos;pyridoxal import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140202</classIRI>
<classLabel>polyamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;polyamine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140201</classIRI>
<classLabel>urea import across plasma membrane</classLabel>
<deletedAxiom>&apos;urea import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140205</classIRI>
<classLabel>oligopeptide import across plasma membrane</classLabel>
<deletedAxiom>&apos;oligopeptide import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019419</classIRI>
<classLabel>sulfate reduction</classLabel>
<deletedAxiom>&apos;sulfate reduction&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140200</classIRI>
<classLabel>adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate</classLabel>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos; EquivalentTo &apos;adenylate cyclase-activating adrenergic receptor signaling pathway&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of heart rate&apos;)</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;regulation of heart rate by chemical signal&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos; SubClassOf &apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;membrane depolarization during action potential&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019420</classIRI>
<classLabel>dissimilatory sulfate reduction</classLabel>
<deletedAxiom>&apos;dissimilatory sulfate reduction&apos; SubClassOf &apos;sulfate reduction&apos;</deletedAxiom>
<newAxiom>&apos;dissimilatory sulfate reduction&apos; SubClassOf &apos;anaerobic respiration&apos;</newAxiom>
<newAxiom>&apos;dissimilatory sulfate reduction&apos; SubClassOf &apos;sulfate assimilation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019424</classIRI>
<classLabel>sulfide oxidation, using siroheme sulfite reductase</classLabel>
<deletedAxiom>&apos;sulfide oxidation, using siroheme sulfite reductase&apos; SubClassOf &apos;sulfide oxidation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019426</classIRI>
<classLabel>bisulfite reduction</classLabel>
<deletedAxiom>&apos;bisulfite reduction&apos; SubClassOf &apos;sulfate reduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019448</classIRI>
<classLabel>L-cysteine catabolic process</classLabel>
<deletedAxiom>&apos;L-cysteine catabolic process&apos; SubClassOf &apos;cellular modified amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-cysteine catabolic process&apos; SubClassOf &apos;serine family amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019471</classIRI>
<classLabel>4-hydroxyproline metabolic process</classLabel>
<newAxiom>&apos;4-hydroxyproline metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019472</classIRI>
<classLabel>4-hydroxyproline biosynthetic process</classLabel>
<newAxiom>&apos;4-hydroxyproline biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
<newAxiom>&apos;4-hydroxyproline biosynthetic process&apos; SubClassOf &apos;amino acid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019477</classIRI>
<classLabel>L-lysine catabolic process</classLabel>
<newAxiom>&apos;L-lysine catabolic process&apos; SubClassOf &apos;aspartate family amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019478</classIRI>
<classLabel>D-amino acid catabolic process</classLabel>
<newAxiom>&apos;D-amino acid catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019470</classIRI>
<classLabel>4-hydroxyproline catabolic process</classLabel>
<newAxiom>&apos;4-hydroxyproline catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044409</classIRI>
<classLabel>entry into host</classLabel>
<deletedAxiom>&apos;entry into host&apos; SubClassOf &apos;movement in host&apos;</deletedAxiom>
<newAxiom>&apos;entry into host&apos; SubClassOf &apos;biological process involved in interaction with host&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019482</classIRI>
<classLabel>beta-alanine metabolic process</classLabel>
<deletedAxiom>&apos;beta-alanine metabolic process&apos; SubClassOf &apos;amino acid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;beta-alanine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019483</classIRI>
<classLabel>beta-alanine biosynthetic process</classLabel>
<newAxiom>&apos;beta-alanine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019484</classIRI>
<classLabel>beta-alanine catabolic process</classLabel>
<newAxiom>&apos;beta-alanine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019499</classIRI>
<classLabel>cyanide metabolic process</classLabel>
<deletedAxiom>&apos;cyanide metabolic process&apos; SubClassOf &apos;organonitrogen compound metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cyanide metabolic process&apos; SubClassOf &apos;organic substance metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071993</classIRI>
<classLabel>phytochelatin transport</classLabel>
<newAxiom>&apos;phytochelatin transport&apos; SubClassOf &apos;organic anion transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140196</classIRI>
<classLabel>positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140195</classIRI>
<classLabel>positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;positive regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140194</classIRI>
<classLabel>negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;negative regulation of G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;negative regulation of multicellular organismal process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140193</classIRI>
<classLabel>regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of system process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140199</classIRI>
<classLabel>negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140192</classIRI>
<classLabel>regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process</classLabel>
<deletedAxiom>&apos;regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf &apos;regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140141</classIRI>
<classLabel>mitochondrial potassium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial potassium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial potassium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140140</classIRI>
<classLabel>mitochondrial guanine nucleotide transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial guanine nucleotide transmembrane transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial guanine nucleotide transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009917</classIRI>
<classLabel>sterol 5-alpha reductase activity</classLabel>
<deletedAxiom>&apos;sterol 5-alpha reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009918</classIRI>
<classLabel>sterol delta7 reductase activity</classLabel>
<deletedAxiom>&apos;sterol delta7 reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140125</classIRI>
<classLabel>thiamine import across plasma membrane</classLabel>
<deletedAxiom>&apos;thiamine import across plasma membrane&apos; SubClassOf &apos;import into cell&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007303</classIRI>
<classLabel>cytoplasmic transport, nurse cell to oocyte</classLabel>
<deletedAxiom>&apos;cytoplasmic transport, nurse cell to oocyte&apos; SubClassOf &apos;cytosolic transport&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transport, nurse cell to oocyte&apos; SubClassOf &apos;cellular process involved in reproduction in multicellular organism&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic transport, nurse cell to oocyte&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ovarian nurse cell to oocyte transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034968</classIRI>
<classLabel>histone lysine methylation</classLabel>
<deletedAxiom>&apos;histone lysine methylation&apos; SubClassOf &apos;histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone lysine methylation&apos; SubClassOf &apos;peptidyl-lysine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034969</classIRI>
<classLabel>histone arginine methylation</classLabel>
<deletedAxiom>&apos;histone arginine methylation&apos; SubClassOf &apos;histone methylation&apos;</deletedAxiom>
<deletedAxiom>&apos;histone arginine methylation&apos; SubClassOf &apos;peptidyl-arginine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034970</classIRI>
<classLabel>histone H3-R2 methylation</classLabel>
<deletedAxiom>&apos;histone H3-R2 methylation&apos; SubClassOf &apos;histone arginine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034971</classIRI>
<classLabel>histone H3-R17 methylation</classLabel>
<deletedAxiom>&apos;histone H3-R17 methylation&apos; SubClassOf &apos;histone arginine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034972</classIRI>
<classLabel>histone H3-R26 methylation</classLabel>
<deletedAxiom>&apos;histone H3-R26 methylation&apos; SubClassOf &apos;histone arginine methylation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046946</classIRI>
<classLabel>hydroxylysine metabolic process</classLabel>
<newAxiom>&apos;hydroxylysine metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170041</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046948</classIRI>
<classLabel>hydroxylysine catabolic process</classLabel>
<newAxiom>&apos;hydroxylysine catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170044</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046947</classIRI>
<classLabel>hydroxylysine biosynthetic process</classLabel>
<newAxiom>&apos;hydroxylysine biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170043</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019379</classIRI>
<classLabel>sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)</classLabel>
<deletedAxiom>&apos;sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)&apos; SubClassOf &apos;sulfate reduction&apos;</deletedAxiom>
<newAxiom>&apos;sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphoadenylyl-sulfate reductase (thioredoxin) activity&apos;</newAxiom>
<newAxiom>&apos;sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)&apos; EquivalentTo &apos;sulfate assimilation&apos; and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphoadenylyl-sulfate reductase (thioredoxin) activity&apos;)</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160129</classIRI>
<classLabel>protein-DNA covalent cross-linking activity</classLabel>
<newAxiom>'protein-DNA covalent cross-linking activity' SubClassOf 'lyase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160128</classIRI>
<classLabel>pH-gated monoatomic ion channel activity</classLabel>
<newAxiom>'pH-gated monoatomic ion channel activity' SubClassOf 'ligand-gated monoatomic ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160127</classIRI>
<classLabel>protein-RNA covalent cross-linking repair</classLabel>
<newAxiom>'protein-RNA covalent cross-linking repair' SubClassOf 'rescue of stalled ribosome'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160126</classIRI>
<classLabel>pH-gated calcium channel activity</classLabel>
<newAxiom>'pH-gated calcium channel activity' SubClassOf 'pH-gated monoatomic ion channel activity'</newAxiom>
<newAxiom>'pH-gated calcium channel activity' SubClassOf 'ligand-gated calcium channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160125</classIRI>
<classLabel>pH-gated sodium channel activity</classLabel>
<newAxiom>'pH-gated sodium channel activity' SubClassOf 'ligand-gated sodium channel activity'</newAxiom>
<newAxiom>'pH-gated sodium channel activity' SubClassOf 'pH-gated monoatomic ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160132</classIRI>
<classLabel>meisosome</classLabel>
<newAxiom>'meisosome' SubClassOf 'cellular anatomical entity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160131</classIRI>
<classLabel>sperm migration through the uterotubal junction</classLabel>
<newAxiom>'sperm migration through the uterotubal junction' SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some 'flagellated sperm motility'</newAxiom>
<newAxiom>'sperm migration through the uterotubal junction' SubClassOf 'cellular process involved in reproduction in multicellular organism'</newAxiom>
<newAxiom>'sperm migration through the uterotubal junction' SubClassOf 'cell migration'</newAxiom>
<newAxiom>'sperm migration through the uterotubal junction' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'multicellular organismal reproductive process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160139</classIRI>
<classLabel>23S rRNA pseudouridine(2605) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(2605) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160138</classIRI>
<classLabel>23S rRNA pseudouridine(2604) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(2604) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160137</classIRI>
<classLabel>23S rRNA pseudouridine(2457) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(2457) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160136</classIRI>
<classLabel>16S rRNA pseudouridine(516) synthase activity</classLabel>
<newAxiom>'16S rRNA pseudouridine(516) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160135</classIRI>
<classLabel>phospholipase C-activating endothelin receptor signaling pathway</classLabel>
<newAxiom>'phospholipase C-activating endothelin receptor signaling pathway' SubClassOf 'endothelin receptor signaling pathway'</newAxiom>
<newAxiom>'phospholipase C-activating endothelin receptor signaling pathway' SubClassOf 'phospholipase C-activating G protein-coupled receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160134</classIRI>
<classLabel>protein-RNA sequence-specific adaptor activity</classLabel>
<newAxiom>'protein-RNA sequence-specific adaptor activity' SubClassOf 'protein-RNA adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160133</classIRI>
<classLabel>bicarbonate channel activity</classLabel>
<newAxiom>'bicarbonate channel activity' SubClassOf 'channel activity'</newAxiom>
<newAxiom>'bicarbonate channel activity' SubClassOf 'bicarbonate transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160143</classIRI>
<classLabel>21S rRNA pseudouridine(2819) synthase activity</classLabel>
<newAxiom>'21S rRNA pseudouridine(2819) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160142</classIRI>
<classLabel>23S rRNA pseudouridine(746) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(746) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160141</classIRI>
<classLabel>23S rRNA pseudouridine(955/2504/2580) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(955/2504/2580) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160140</classIRI>
<classLabel>23S rRNA pseudouridine(1911/1915/1917) synthase activity</classLabel>
<newAxiom>'23S rRNA pseudouridine(1911/1915/1917) synthase activity' SubClassOf 'rRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160149</classIRI>
<classLabel>tRNA pseudouridine(65) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(65) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160148</classIRI>
<classLabel>tRNA pseudouridine(55) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(55) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160147</classIRI>
<classLabel>tRNA pseudouridine(38-40) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(38-40) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160145</classIRI>
<classLabel>negative regulation of GDF15-GFRAL signaling pathway</classLabel>
<newAxiom>'negative regulation of GDF15-GFRAL signaling pathway' SubClassOf 'regulation of cellular response to stress'</newAxiom>
<newAxiom>'negative regulation of GDF15-GFRAL signaling pathway' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'GDF15-GFRAL signaling pathway'</newAxiom>
<newAxiom>'negative regulation of GDF15-GFRAL signaling pathway' SubClassOf 'negative regulation of signal transduction'</newAxiom>
<newAxiom>'negative regulation of GDF15-GFRAL signaling pathway' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'GDF15-GFRAL signaling pathway')</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160144</classIRI>
<classLabel>GDF15-GFRAL signaling pathway</classLabel>
<newAxiom>'GDF15-GFRAL signaling pathway' SubClassOf 'cellular response to stress'</newAxiom>
<newAxiom>'GDF15-GFRAL signaling pathway' SubClassOf 'glial cell-derived neurotrophic factor receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160154</classIRI>
<classLabel>tRNA pseudouridine(38/39) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(38/39) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160153</classIRI>
<classLabel>mitochondrial tRNA pseudouridine(27/28) synthase activity</classLabel>
<newAxiom>'mitochondrial tRNA pseudouridine(27/28) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160152</classIRI>
<classLabel>tRNA pseudouridine(31) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(31) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160151</classIRI>
<classLabel>tRNA pseudouridine(32) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(32) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160150</classIRI>
<classLabel>tRNA pseudouridine(13) synthase activity</classLabel>
<newAxiom>'tRNA pseudouridine(13) synthase activity' SubClassOf 'tRNA pseudouridine synthase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170041</classIRI>
<classLabel>non-proteinogenic amino acid metabolic process</classLabel>
<newAxiom>'non-proteinogenic amino acid metabolic process' SubClassOf 'amino acid metabolic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid metabolic process' SubClassOf 'organonitrogen compound metabolic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid metabolic process' SubClassOf 'carboxylic acid metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170040</classIRI>
<classLabel>proteinogenic amino acid catabolic process</classLabel>
<newAxiom>'proteinogenic amino acid catabolic process' SubClassOf 'carboxylic acid catabolic process'</newAxiom>
<newAxiom>'proteinogenic amino acid catabolic process' SubClassOf 'proteinogenic amino acid metabolic process'</newAxiom>
<newAxiom>'proteinogenic amino acid catabolic process' SubClassOf 'organonitrogen compound catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170043</classIRI>
<classLabel>non-proteinogenic amino acid biosynthetic process</classLabel>
<newAxiom>'non-proteinogenic amino acid biosynthetic process' SubClassOf 'organonitrogen compound biosynthetic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid biosynthetic process' SubClassOf 'carboxylic acid biosynthetic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid biosynthetic process' SubClassOf 'non-proteinogenic amino acid metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170038</classIRI>
<classLabel>proteinogenic amino acid biosynthetic process</classLabel>
<newAxiom>'proteinogenic amino acid biosynthetic process' SubClassOf 'proteinogenic amino acid metabolic process'</newAxiom>
<newAxiom>'proteinogenic amino acid biosynthetic process' SubClassOf 'carboxylic acid biosynthetic process'</newAxiom>
<newAxiom>'proteinogenic amino acid biosynthetic process' SubClassOf 'organonitrogen compound biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170037</classIRI>
<classLabel>export from the mitochondrion</classLabel>
<newAxiom>'export from the mitochondrion' SubClassOf 'mitochondrial transmembrane transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170039</classIRI>
<classLabel>proteinogenic amino acid metabolic process</classLabel>
<newAxiom>'proteinogenic amino acid metabolic process' SubClassOf 'carboxylic acid metabolic process'</newAxiom>
<newAxiom>'proteinogenic amino acid metabolic process' SubClassOf 'amino acid metabolic process'</newAxiom>
<newAxiom>'proteinogenic amino acid metabolic process' SubClassOf 'organonitrogen compound metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170034</classIRI>
<classLabel>L-amino acid biosynthetic process</classLabel>
<newAxiom>'L-amino acid biosynthetic process' SubClassOf 'L-amino acid metabolic process'</newAxiom>
<newAxiom>'L-amino acid biosynthetic process' SubClassOf 'alpha-amino acid biosynthetic process'</newAxiom>
<newAxiom>'L-amino acid biosynthetic process' SubClassOf 'amino acid biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170033</classIRI>
<classLabel>L-amino acid metabolic process</classLabel>
<newAxiom>'L-amino acid metabolic process' SubClassOf 'alpha-amino acid metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170036</classIRI>
<classLabel>import into the mitochondrion</classLabel>
<newAxiom>'import into the mitochondrion' SubClassOf 'mitochondrial transmembrane transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170035</classIRI>
<classLabel>L-amino acid catabolic process</classLabel>
<newAxiom>'L-amino acid catabolic process' SubClassOf 'L-amino acid metabolic process'</newAxiom>
<newAxiom>'L-amino acid catabolic process' SubClassOf 'alpha-amino acid catabolic process'</newAxiom>
<newAxiom>'L-amino acid catabolic process' SubClassOf 'amino acid catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170045</classIRI>
<classLabel>isopentenyl pyrophosphate transmembrate transporter activity</classLabel>
<newAxiom>'isopentenyl pyrophosphate transmembrate transporter activity' SubClassOf 'organophosphate ester transmembrane transporter activity'</newAxiom>
<newAxiom>'isopentenyl pyrophosphate transmembrate transporter activity' SubClassOf 'phospholipid transporter activity'</newAxiom>
<newAxiom>'isopentenyl pyrophosphate transmembrate transporter activity' SubClassOf 'organic anion transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170044</classIRI>
<classLabel>non-proteinogenic amino acid catabolic process</classLabel>
<newAxiom>'non-proteinogenic amino acid catabolic process' SubClassOf 'non-proteinogenic amino acid metabolic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid catabolic process' SubClassOf 'carboxylic acid catabolic process'</newAxiom>
<newAxiom>'non-proteinogenic amino acid catabolic process' SubClassOf 'organonitrogen compound catabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170046</classIRI>
<classLabel>isopentenyl pyrophosphate import into mitochondrion</classLabel>
<newAxiom>'isopentenyl pyrophosphate import into mitochondrion' SubClassOf 'mitochondrial transmembrane transport'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180028</classIRI>
<classLabel>mitotic spindle pole body attachment site</classLabel>
<newAxiom>'mitotic spindle pole body attachment site' SubClassOf 'microtubule organizing center attachment site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180027</classIRI>
<classLabel>inner nuclear membrane-associated protein degradation pathway</classLabel>
<newAxiom>'inner nuclear membrane-associated protein degradation pathway' SubClassOf 'nuclear protein quality control by the ubiquitin-proteasome system'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180029</classIRI>
<classLabel>phosphate ion export across plasma membrane</classLabel>
<newAxiom>'phosphate ion export across plasma membrane' SubClassOf 'phosphate ion transmembrane transport'</newAxiom>
<newAxiom>'phosphate ion export across plasma membrane' SubClassOf 'export across plasma membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180030</classIRI>
<classLabel>inositol phosphate kinase activity</classLabel>
<newAxiom>'inositol phosphate kinase activity' SubClassOf 'kinase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141139</classIRI>
<classLabel>symbiont-mediated disruption of host mucosa</classLabel>
<newAxiom>'symbiont-mediated disruption of host mucosa' SubClassOf 'disruption of tissue in another organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141137</classIRI>
<classLabel>positive regulation of gene expression, epigenetic</classLabel>
<newAxiom>'positive regulation of gene expression, epigenetic' SubClassOf 'positive regulation of gene expression'</newAxiom>
<newAxiom>'positive regulation of gene expression, epigenetic' SubClassOf 'epigenetic regulation of gene expression'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141142</classIRI>
<classLabel>symbiont-mediated migration across host tissue barrier</classLabel>
<newAxiom>'symbiont-mediated migration across host tissue barrier' SubClassOf 'migration in host'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141141</classIRI>
<classLabel>evasion of symbiont recognition by host pattern recognition receptor</classLabel>
<newAxiom>'evasion of symbiont recognition by host pattern recognition receptor' SubClassOf 'evasion of host innate immune recognition'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141140</classIRI>
<classLabel>symbiont-mediated suppression of host immunoglobulin-mediated immune response</classLabel>
<newAxiom>'symbiont-mediated suppression of host immunoglobulin-mediated immune response' SubClassOf 'symbiont-mediated suppression of host immune response'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141143</classIRI>
<classLabel>symbiont-mediated disruption of host cell adhesion to extracellular matrix</classLabel>
<newAxiom>'symbiont-mediated disruption of host cell adhesion to extracellular matrix' SubClassOf 'symbiont-mediated perturbation of host cellular process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141128</classIRI>
<classLabel>symbiont-mediated non-specific activation of host T-cells</classLabel>
<newAxiom>'symbiont-mediated non-specific activation of host T-cells' SubClassOf 'symbiont-mediated perturbation of host cellular process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141127</classIRI>
<classLabel>symbiont-mediated perturbation of host Rab signal transduction</classLabel>
<newAxiom>'symbiont-mediated perturbation of host Rab signal transduction' SubClassOf 'symbiont-mediated perturbation of host small GTPase-mediated signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141126</classIRI>
<classLabel>short-chain fatty acyl-CoA hydrolase activity</classLabel>
<newAxiom>'short-chain fatty acyl-CoA hydrolase activity' SubClassOf 'fatty acyl-CoA hydrolase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141125</classIRI>
<classLabel>tRNA-queuosine(34) galactosyltransferase activity</classLabel>
<newAxiom>'tRNA-queuosine(34) galactosyltransferase activity' SubClassOf 'catalytic activity, acting on a tRNA'</newAxiom>
<newAxiom>'tRNA-queuosine(34) galactosyltransferase activity' SubClassOf 'UDP-galactosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141129</classIRI>
<classLabel>symbiont-mediated suppression of host signal transduction pathway via antagonism of host cell surface receptor</classLabel>
<newAxiom>'symbiont-mediated suppression of host signal transduction pathway via antagonism of host cell surface receptor' SubClassOf 'symbiont-mediated suppression of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141131</classIRI>
<classLabel>DNA N6-methyladenine demethylase activity</classLabel>
<newAxiom>'DNA N6-methyladenine demethylase activity' SubClassOf 'DNA demethylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141130</classIRI>
<classLabel>symbiont-mediated inactivation of host ribosome</classLabel>
<newAxiom>'symbiont-mediated inactivation of host ribosome' SubClassOf 'symbiont-mediated suppression of host translation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141135</classIRI>
<classLabel>symbiont-mediated suppression of host chemokine signal transduction pathway</classLabel>
<newAxiom>'symbiont-mediated suppression of host chemokine signal transduction pathway' SubClassOf 'symbiont-mediated suppression of host G protein-coupled receptor signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141134</classIRI>
<classLabel>symbiont-mediated activation of host signal transduction pathway via agonism of host cell surface receptor</classLabel>
<newAxiom>'symbiont-mediated activation of host signal transduction pathway via agonism of host cell surface receptor' SubClassOf 'symbiont-mediated activation of host signal transduction pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141133</classIRI>
<classLabel>diphthine methyl ester synthase activity</classLabel>
<newAxiom>'diphthine methyl ester synthase activity' SubClassOf 'S-adenosylmethionine-dependent methyltransferase activity'</newAxiom>
<newAxiom>'diphthine methyl ester synthase activity' SubClassOf 'protein methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141132</classIRI>
<classLabel>defense response to host</classLabel>
<newAxiom>'defense response to host' SubClassOf 'defense response to other organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141117</classIRI>
<classLabel>symbiont-mediated suppression of host complement activation by recruitment of complement control protein</classLabel>
<newAxiom>'symbiont-mediated suppression of host complement activation by recruitment of complement control protein' SubClassOf 'symbiont-mediated suppression of host complement activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141116</classIRI>
<classLabel>symbiont-mediated suppression of host complement activation by complement sequestering</classLabel>
<newAxiom>'symbiont-mediated suppression of host complement activation by complement sequestering' SubClassOf 'symbiont-mediated suppression of host complement activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141115</classIRI>
<classLabel>symbiont-mediated suppression of host complement activation by inactivation of complement proteins</classLabel>
<newAxiom>'symbiont-mediated suppression of host complement activation by inactivation of complement proteins' SubClassOf 'symbiont-mediated suppression of host complement activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141114</classIRI>
<classLabel>obsolete symbiont-mediated suppression of host complement activation</classLabel>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141119</classIRI>
<classLabel>chromosomal DNA methylation maintenance following DNA replication</classLabel>
<newAxiom>'chromosomal DNA methylation maintenance following DNA replication' SubClassOf 'chromatin organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141118</classIRI>
<classLabel>nitric oxide dioxygenase activity, heme protein as donor</classLabel>
<newAxiom>'nitric oxide dioxygenase activity, heme protein as donor' SubClassOf 'oxidoreductase activity, acting on a heme group of donors'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141124</classIRI>
<classLabel>intracellular signaling cassette</classLabel>
<newAxiom>'intracellular signaling cassette' SubClassOf 'intracellular signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141123</classIRI>
<classLabel>dermonecrosis in another organism</classLabel>
<newAxiom>'dermonecrosis in another organism' SubClassOf 'disruption of tissue in another organism'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141122</classIRI>
<classLabel>nitrogen-oxygen hydrolyase activity</classLabel>
<newAxiom>'nitrogen-oxygen hydrolyase activity' SubClassOf 'lyase activity'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>