<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
1279
</numberChangedClasses>
<numberNewClasses>
17
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046885</classIRI>
<classLabel>regulation of hormone biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of hormone biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of hormone biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046886</classIRI>
<classLabel>positive regulation of hormone biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of hormone biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of hormone biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019261</classIRI>
<classLabel>1,4-dichlorobenzene catabolic process</classLabel>
<newAxiom>&apos;1,4-dichlorobenzene catabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044242</classIRI>
<classLabel>cellular lipid catabolic process</classLabel>
<deletedAxiom>&apos;cellular lipid catabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular lipid catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular lipid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044237</classIRI>
<classLabel>cellular metabolic process</classLabel>
<deletedAxiom>&apos;cellular metabolic process&apos; SubClassOf &apos;metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular metabolic process&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044269</classIRI>
<classLabel>glycerol ether catabolic process</classLabel>
<deletedAxiom>&apos;glycerol ether catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044255</classIRI>
<classLabel>cellular lipid metabolic process</classLabel>
<deletedAxiom>&apos;cellular lipid metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular lipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071875</classIRI>
<classLabel>adrenergic receptor signaling pathway</classLabel>
<newAxiom>&apos;adrenergic receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adrenergic receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044248</classIRI>
<classLabel>cellular catabolic process</classLabel>
<deletedAxiom>&apos;cellular catabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044249</classIRI>
<classLabel>cellular biosynthetic process</classLabel>
<deletedAxiom>&apos;cellular biosynthetic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044272</classIRI>
<classLabel>sulfur compound biosynthetic process</classLabel>
<deletedAxiom>&apos;sulfur compound biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;sulfur compound biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103086</classIRI>
<classLabel>methylthiopentylmalate isomerase activity</classLabel>
<deletedAxiom>&apos;methylthiopentylmalate isomerase activity&apos; SubClassOf &apos;intramolecular hydroxytransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103088</classIRI>
<classLabel>2-(6&apos;-methylthio)hexylmalate synthase activity</classLabel>
<deletedAxiom>&apos;2-(6&apos;-methylthio)hexylmalate synthase activity&apos; SubClassOf &apos;acyltransferase activity, acyl groups converted into alkyl on transfer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103089</classIRI>
<classLabel>methylthiohexylmalate isomerase activity</classLabel>
<deletedAxiom>&apos;methylthiohexylmalate isomerase activity&apos; SubClassOf &apos;intramolecular hydroxytransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103082</classIRI>
<classLabel>2-(4&apos;-methylthio)butylmalate synthase activity</classLabel>
<deletedAxiom>&apos;2-(4&apos;-methylthio)butylmalate synthase activity&apos; SubClassOf &apos;acyltransferase activity, acyl groups converted into alkyl on transfer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103083</classIRI>
<classLabel>methylthiobutylmalate isomerase activity</classLabel>
<deletedAxiom>&apos;methylthiobutylmalate isomerase activity&apos; SubClassOf &apos;intramolecular hydroxytransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103085</classIRI>
<classLabel>2-(5&apos;-methylthio)pentylmalate synthase activity</classLabel>
<deletedAxiom>&apos;2-(5&apos;-methylthio)pentylmalate synthase activity&apos; SubClassOf &apos;acyltransferase activity, acyl groups converted into alkyl on transfer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103080</classIRI>
<classLabel>methylthiopropylmalate isomerase activity</classLabel>
<deletedAxiom>&apos;methylthiopropylmalate isomerase activity&apos; SubClassOf &apos;intramolecular hydroxytransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103079</classIRI>
<classLabel>2-(3&apos;-methylthio)propylmalate synthase activity</classLabel>
<deletedAxiom>&apos;2-(3&apos;-methylthio)propylmalate synthase activity&apos; SubClassOf &apos;acyltransferase activity, acyl groups converted into alkyl on transfer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103097</classIRI>
<classLabel>CYP79F1 trihomomethionine monooxygenase activity</classLabel>
<deletedAxiom>&apos;CYP79F1 trihomomethionine monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103098</classIRI>
<classLabel>CYP79F1 tetrahomomethionine monooxygenase activity</classLabel>
<deletedAxiom>&apos;CYP79F1 tetrahomomethionine monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103096</classIRI>
<classLabel>CYP79F1 dihomomethionine monooxygenase activity</classLabel>
<deletedAxiom>&apos;CYP79F1 dihomomethionine monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103091</classIRI>
<classLabel>2-(7&apos;-methylthio)heptylmalate synthase activity</classLabel>
<deletedAxiom>&apos;2-(7&apos;-methylthio)heptylmalate synthase activity&apos; SubClassOf &apos;acyltransferase activity, acyl groups converted into alkyl on transfer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103092</classIRI>
<classLabel>methylthioalkylmalate isomerase activity</classLabel>
<deletedAxiom>&apos;methylthioalkylmalate isomerase activity&apos; SubClassOf &apos;intramolecular hydroxytransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103044</classIRI>
<classLabel>ribosomal protein S6 glutamate-glutamate ligase activity</classLabel>
<deletedAxiom>&apos;ribosomal protein S6 glutamate-glutamate ligase activity&apos; SubClassOf &apos;ribosomal S6-glutamic acid ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103054</classIRI>
<classLabel>gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)</classLabel>
<deletedAxiom>&apos;gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103055</classIRI>
<classLabel>gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103056</classIRI>
<classLabel>gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103057</classIRI>
<classLabel>gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009850</classIRI>
<classLabel>auxin metabolic process</classLabel>
<deletedAxiom>&apos;auxin metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009851</classIRI>
<classLabel>auxin biosynthetic process</classLabel>
<deletedAxiom>&apos;auxin biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103008</classIRI>
<classLabel>4-chloro-2-methylphenoxyacetate oxygenase activity</classLabel>
<deletedAxiom>&apos;4-chloro-2-methylphenoxyacetate oxygenase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103009</classIRI>
<classLabel>3-chlorotoluene monooxygenase activity</classLabel>
<deletedAxiom>&apos;3-chlorotoluene monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103003</classIRI>
<classLabel>oleate peroxygenase activity</classLabel>
<deletedAxiom>&apos;oleate peroxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on peroxide as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103005</classIRI>
<classLabel>9,10-epoxystearate hydrolase activity</classLabel>
<deletedAxiom>&apos;9,10-epoxystearate hydrolase activity&apos; SubClassOf &apos;ether hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010851</classIRI>
<classLabel>cyclase regulator activity</classLabel>
<newAxiom>&apos;cyclase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007206</classIRI>
<classLabel>phospholipase C-activating G protein-coupled glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;phospholipase C-activating G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;PLC activating G protein-coupled glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007208</classIRI>
<classLabel>phospholipase C-activating serotonin receptor signaling pathway</classLabel>
<newAxiom>&apos;phospholipase C-activating serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Gq/11-coupled serotonin receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010856</classIRI>
<classLabel>adenylate cyclase activator activity</classLabel>
<newAxiom>&apos;adenylate cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;adenylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010858</classIRI>
<classLabel>calcium-dependent protein kinase regulator activity</classLabel>
<newAxiom>&apos;calcium-dependent protein kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium-dependent protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010852</classIRI>
<classLabel>cyclase inhibitor activity</classLabel>
<newAxiom>&apos;cyclase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010853</classIRI>
<classLabel>cyclase activator activity</classLabel>
<newAxiom>&apos;cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010854</classIRI>
<classLabel>adenylate cyclase regulator activity</classLabel>
<newAxiom>&apos;adenylate cyclase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;adenylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010855</classIRI>
<classLabel>adenylate cyclase inhibitor activity</classLabel>
<newAxiom>&apos;adenylate cyclase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;adenylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007210</classIRI>
<classLabel>serotonin receptor signaling pathway</classLabel>
<newAxiom>&apos;serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;serotonin receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007213</classIRI>
<classLabel>G protein-coupled acetylcholine receptor signaling pathway</classLabel>
<newAxiom>&apos;G protein-coupled acetylcholine receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007215</classIRI>
<classLabel>glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007214</classIRI>
<classLabel>gamma-aminobutyric acid signaling pathway</classLabel>
<newAxiom>&apos;gamma-aminobutyric acid signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;GABA receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007216</classIRI>
<classLabel>G protein-coupled glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010867</classIRI>
<classLabel>positive regulation of triglyceride biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of triglyceride biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010868</classIRI>
<classLabel>negative regulation of triglyceride biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of triglyceride biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019207</classIRI>
<classLabel>kinase regulator activity</classLabel>
<newAxiom>&apos;kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019208</classIRI>
<classLabel>phosphatase regulator activity</classLabel>
<newAxiom>&apos;phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019209</classIRI>
<classLabel>kinase activator activity</classLabel>
<newAxiom>&apos;kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010866</classIRI>
<classLabel>regulation of triglyceride biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of triglyceride biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046811</classIRI>
<classLabel>histone deacetylase inhibitor activity</classLabel>
<newAxiom>&apos;histone deacetylase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;histone deacetylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103010</classIRI>
<classLabel>gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)</classLabel>
<deletedAxiom>&apos;gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019210</classIRI>
<classLabel>kinase inhibitor activity</classLabel>
<newAxiom>&apos;kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019211</classIRI>
<classLabel>phosphatase activator activity</classLabel>
<newAxiom>&apos;phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019212</classIRI>
<classLabel>phosphatase inhibitor activity</classLabel>
<newAxiom>&apos;phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019213</classIRI>
<classLabel>deacetylase activity</classLabel>
<deletedAxiom>&apos;deacetylase activity&apos; SubClassOf &apos;hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0160215</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019217</classIRI>
<classLabel>regulation of fatty acid metabolic process</classLabel>
<newAxiom>&apos;regulation of fatty acid metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009892</classIRI>
<classLabel>negative regulation of metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of metabolic process&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of metabolic process&apos; SubClassOf &apos;negative regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009893</classIRI>
<classLabel>positive regulation of metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of metabolic process&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of metabolic process&apos; SubClassOf &apos;positive regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019222</classIRI>
<classLabel>regulation of metabolic process</classLabel>
<deletedAxiom>&apos;regulation of metabolic process&apos; SubClassOf &apos;regulation of biological process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of metabolic process&apos; SubClassOf &apos;regulation of cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010895</classIRI>
<classLabel>negative regulation of ergosterol biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of ergosterol biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010896</classIRI>
<classLabel>regulation of triglyceride catabolic process</classLabel>
<deletedAxiom>&apos;regulation of triglyceride catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010897</classIRI>
<classLabel>negative regulation of triglyceride catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of triglyceride catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010898</classIRI>
<classLabel>positive regulation of triglyceride catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of triglyceride catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019243</classIRI>
<classLabel>methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione</classLabel>
<newAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactoylglutathione lyase activity&apos;</newAxiom>
<newAxiom>&apos;methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;hydroxyacylglutathione hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046863</classIRI>
<classLabel>ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity</classLabel>
<newAxiom>&apos;ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ribulose-bisphosphate carboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019248</classIRI>
<classLabel>D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde</classLabel>
<newAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;methylglyoxal reductase (NADH) activity&apos;</newAxiom>
<newAxiom>&apos;D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046785</classIRI>
<classLabel>microtubule polymerization</classLabel>
<newAxiom>&apos;microtubule polymerization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;microtubule nucleation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007186</classIRI>
<classLabel>G protein-coupled receptor signaling pathway</classLabel>
<newAxiom>&apos;G protein-coupled receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046773</classIRI>
<classLabel>symbiont-mediated suppression of host translation termination</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host translation termination&apos; SubClassOf &apos;symbiont-mediated suppression of host translation&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host translation termination&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046775</classIRI>
<classLabel>suppression by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;negative regulation of cytokine production&apos;</deletedAxiom>
<deletedAxiom>&apos;suppression by virus of host cytokine production&apos; EquivalentTo &apos;perturbation by virus of host immune response&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cytokine production&apos;)</deletedAxiom>
<newAxiom>&apos;suppression by virus of host cytokine production&apos; SubClassOf &apos;symbiont-mediated suppression of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032129</classIRI>
<classLabel>histone H3K9 deacetylase activity</classLabel>
<newAxiom>&apos;histone H3K9 deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141221</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007196</classIRI>
<classLabel>adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007198</classIRI>
<classLabel>adenylate cyclase-inhibiting serotonin receptor signaling pathway</classLabel>
<newAxiom>&apos;adenylate cyclase-inhibiting serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Gi/o-coupled serotonin receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010706</classIRI>
<classLabel>ganglioside biosynthetic process via lactosylceramide</classLabel>
<newAxiom>&apos;ganglioside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactosylceramide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010707</classIRI>
<classLabel>globoside biosynthetic process via lactosylceramide</classLabel>
<newAxiom>&apos;globoside biosynthetic process via lactosylceramide&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;lactosylceramide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010728</classIRI>
<classLabel>regulation of hydrogen peroxide biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of hydrogen peroxide biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010729</classIRI>
<classLabel>positive regulation of hydrogen peroxide biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of hydrogen peroxide biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010730</classIRI>
<classLabel>negative regulation of hydrogen peroxide biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of hydrogen peroxide biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019111</classIRI>
<classLabel>phenanthrol sulfotransferase activity</classLabel>
<deletedAxiom>&apos;phenanthrol sulfotransferase activity&apos; SubClassOf &apos;sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007131</classIRI>
<classLabel>reciprocal meiotic recombination</classLabel>
<newAxiom>&apos;reciprocal meiotic recombination&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010794</classIRI>
<classLabel>regulation of dolichol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of dolichol biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010796</classIRI>
<classLabel>regulation of multivesicular body size</classLabel>
<deletedAxiom>&apos;regulation of multivesicular body size&apos; SubClassOf &apos;regulation of endosome size&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010797</classIRI>
<classLabel>regulation of multivesicular body size involved in endosome transport</classLabel>
<deletedAxiom>&apos;regulation of multivesicular body size involved in endosome transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endosome transport via multivesicular body sorting pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of multivesicular body size involved in endosome transport&apos; SubClassOf &apos;regulation of multivesicular body size&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of multivesicular body size involved in endosome transport&apos; EquivalentTo &apos;regulation of multivesicular body size&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;endosomal transport&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010798</classIRI>
<classLabel>regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism</classLabel>
<deletedAxiom>&apos;regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism&apos; EquivalentTo &apos;regulation of multivesicular body size&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ubiquitin-dependent protein catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism&apos; SubClassOf &apos;regulation of multivesicular body size&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020013</classIRI>
<classLabel>modulation by symbiont of host erythrocyte aggregation</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host erythrocyte aggregation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;erythrocyte aggregation&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host erythrocyte aggregation&apos; EquivalentTo &apos;symbiont-mediated perturbation of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;erythrocyte aggregation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032000</classIRI>
<classLabel>positive regulation of fatty acid beta-oxidation</classLabel>
<deletedAxiom>&apos;positive regulation of fatty acid beta-oxidation&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010698</classIRI>
<classLabel>acetyltransferase activator activity</classLabel>
<newAxiom>&apos;acetyltransferase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;acetyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019057</classIRI>
<classLabel>symbiont-mediated perturbation of host translation</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host translation&apos; SubClassOf &apos;symbiont-mediated perturbation of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host translation&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032041</classIRI>
<classLabel>NAD-dependent histone H3K14 deacetylase activity</classLabel>
<deletedAxiom>&apos;NAD-dependent histone H3K14 deacetylase activity&apos; SubClassOf &apos;histone H3K14 deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;NAD-dependent histone H3K14 deacetylase activity&apos; SubClassOf &apos;histone H3K deacetylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044068</classIRI>
<classLabel>symbiont-mediated perturbation of host cellular process</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host cellular process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044069</classIRI>
<classLabel>modulation by symbiont of host anion transport</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host anion transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;monoatomic anion transport&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host anion transport&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host anion transport&apos; EquivalentTo &apos;symbiont-mediated perturbation of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;monoatomic anion transport&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044080</classIRI>
<classLabel>symbiont-mediated perturbation of host cGMP-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host cGMP-mediated signal transduction&apos; SubClassOf &apos;regulation of cGMP-mediated signaling&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated perturbation of host cGMP-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated perturbation of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044077</classIRI>
<classLabel>symbiont-mediated perturbation of host receptor-mediated endocytosis</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host receptor-mediated endocytosis&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host receptor-mediated endocytosis&apos; SubClassOf &apos;symbiont-mediated perturbation of host vesicle-mediated transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044079</classIRI>
<classLabel>symbiont-mediated perturbation of host neurotransmitter secretion</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host neurotransmitter secretion&apos; SubClassOf &apos;symbiont-mediated suppression of host exocytosis&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host neurotransmitter secretion&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010602</classIRI>
<classLabel>regulation of 1-aminocyclopropane-1-carboxylate metabolic process</classLabel>
<newAxiom>&apos;regulation of 1-aminocyclopropane-1-carboxylate metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009691</classIRI>
<classLabel>cytokinin biosynthetic process</classLabel>
<deletedAxiom>&apos;cytokinin biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010566</classIRI>
<classLabel>regulation of ketone biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of ketone biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ketone biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of ketone biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010567</classIRI>
<classLabel>regulation of ketone catabolic process</classLabel>
<deletedAxiom>&apos;regulation of ketone catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ketone catabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of ketone catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010578</classIRI>
<classLabel>regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;regulation of adenylate cyclase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;regulation of adenylate cyclase activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;adenylate cyclase-modulating G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;adenylate cyclase-modulating G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046504</classIRI>
<classLabel>glycerol ether biosynthetic process</classLabel>
<deletedAxiom>&apos;glycerol ether biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046503</classIRI>
<classLabel>glycerolipid catabolic process</classLabel>
<deletedAxiom>&apos;glycerolipid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glycerolipid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046505</classIRI>
<classLabel>sulfolipid metabolic process</classLabel>
<deletedAxiom>&apos;sulfolipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;sulfolipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0095500</classIRI>
<classLabel>acetylcholine receptor signaling pathway</classLabel>
<newAxiom>&apos;acetylcholine receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010508</classIRI>
<classLabel>positive regulation of autophagy</classLabel>
<deletedAxiom>&apos;positive regulation of autophagy&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of autophagy&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010506</classIRI>
<classLabel>regulation of autophagy</classLabel>
<deletedAxiom>&apos;regulation of autophagy&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of autophagy&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010507</classIRI>
<classLabel>negative regulation of autophagy</classLabel>
<deletedAxiom>&apos;negative regulation of autophagy&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of autophagy&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010511</classIRI>
<classLabel>regulation of phosphatidylinositol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylinositol biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010512</classIRI>
<classLabel>negative regulation of phosphatidylinositol biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylinositol biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010513</classIRI>
<classLabel>positive regulation of phosphatidylinositol biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylinositol biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010520</classIRI>
<classLabel>regulation of reciprocal meiotic recombination</classLabel>
<newAxiom>&apos;regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;regulation of reproductive process&apos;</newAxiom>
<newAxiom>&apos;regulation of reciprocal meiotic recombination&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010521</classIRI>
<classLabel>telomerase inhibitor activity</classLabel>
<newAxiom>&apos;telomerase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;telomerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010526</classIRI>
<classLabel>retrotransposon silencing</classLabel>
<deletedAxiom>&apos;retrotransposon silencing&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<newAxiom>&apos;retrotransposon silencing&apos; SubClassOf &apos;negative regulation of gene expression, epigenetic&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009555</classIRI>
<classLabel>pollen development</classLabel>
<newAxiom>&apos;pollen development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;microsporogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010556</classIRI>
<classLabel>regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010557</classIRI>
<classLabel>positive regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010558</classIRI>
<classLabel>negative regulation of macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of macromolecule biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010562</classIRI>
<classLabel>positive regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphorus metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of phosphorus metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010563</classIRI>
<classLabel>negative regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphorus metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of phosphorus metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010565</classIRI>
<classLabel>regulation of cellular ketone metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular ketone metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular ketone metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cellular ketone metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034408</classIRI>
<classLabel>ascospore wall beta-glucan metabolic process</classLabel>
<newAxiom>&apos;ascospore wall beta-glucan metabolic process&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034412</classIRI>
<classLabel>ascospore wall beta-glucan biosynthetic process</classLabel>
<deletedAxiom>&apos;ascospore wall beta-glucan biosynthetic process&apos; SubClassOf &apos;meiotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046414</classIRI>
<classLabel>organomercury biosynthetic process</classLabel>
<deletedAxiom>&apos;organomercury biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;organomercury biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046467</classIRI>
<classLabel>membrane lipid biosynthetic process</classLabel>
<deletedAxiom>&apos;membrane lipid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046466</classIRI>
<classLabel>membrane lipid catabolic process</classLabel>
<deletedAxiom>&apos;membrane lipid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;membrane lipid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046461</classIRI>
<classLabel>neutral lipid catabolic process</classLabel>
<deletedAxiom>&apos;neutral lipid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046460</classIRI>
<classLabel>neutral lipid biosynthetic process</classLabel>
<deletedAxiom>&apos;neutral lipid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046485</classIRI>
<classLabel>ether lipid metabolic process</classLabel>
<deletedAxiom>&apos;ether lipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;ether lipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046486</classIRI>
<classLabel>glycerolipid metabolic process</classLabel>
<deletedAxiom>&apos;glycerolipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glycerolipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009403</classIRI>
<classLabel>toxin biosynthetic process</classLabel>
<deletedAxiom>&apos;toxin biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009404</classIRI>
<classLabel>toxin metabolic process</classLabel>
<deletedAxiom>&apos;toxin metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010439</classIRI>
<classLabel>regulation of glucosinolate biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of glucosinolate biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010337</classIRI>
<classLabel>regulation of salicylic acid metabolic process</classLabel>
<newAxiom>&apos;regulation of salicylic acid metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010364</classIRI>
<classLabel>regulation of ethylene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of ethylene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010365</classIRI>
<classLabel>positive regulation of ethylene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of ethylene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010366</classIRI>
<classLabel>negative regulation of ethylene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of ethylene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010371</classIRI>
<classLabel>regulation of gibberellin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of gibberellin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gibberellin biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010372</classIRI>
<classLabel>positive regulation of gibberellin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of gibberellin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010373</classIRI>
<classLabel>negative regulation of gibberellin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of gibberellin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009395</classIRI>
<classLabel>phospholipid catabolic process</classLabel>
<deletedAxiom>&apos;phospholipid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phospholipid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046379</classIRI>
<classLabel>extracellular polysaccharide metabolic process</classLabel>
<deletedAxiom>&apos;extracellular polysaccharide metabolic process&apos; SubClassOf &apos;polysaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010307</classIRI>
<classLabel>acetylglutamate kinase regulator activity</classLabel>
<newAxiom>&apos;acetylglutamate kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;acetylglutamate kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009255</classIRI>
<classLabel>Entner-Doudoroff pathway through 6-phosphogluconate</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway through 6-phosphogluconate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000820</classIRI>
<classLabel>regulation of glutamine family amino acid metabolic process</classLabel>
<newAxiom>&apos;regulation of glutamine family amino acid metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000821</classIRI>
<classLabel>regulation of arginine metabolic process</classLabel>
<newAxiom>&apos;regulation of arginine metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046211</classIRI>
<classLabel>(+)-camphor biosynthetic process</classLabel>
<newAxiom>&apos;(+)-camphor biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;geranyl-diphosphate cyclase activity&apos;</newAxiom>
<newAxiom>&apos;(+)-camphor biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;(+)-borneol dehydrogenase activity&apos;</newAxiom>
<newAxiom>&apos;(+)-camphor biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;obsolete monoterpenyl-diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061857</classIRI>
<classLabel>endoplasmic reticulum stress-induced pre-emptive quality control</classLabel>
<newAxiom>&apos;endoplasmic reticulum stress-induced pre-emptive quality control&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;proteasome-mediated ubiquitin-dependent protein catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009111</classIRI>
<classLabel>vitamin catabolic process</classLabel>
<deletedAxiom>&apos;vitamin catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009110</classIRI>
<classLabel>vitamin biosynthetic process</classLabel>
<deletedAxiom>&apos;vitamin biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010109</classIRI>
<classLabel>regulation of photosynthesis</classLabel>
<deletedAxiom>&apos;regulation of photosynthesis&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of photosynthesis&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010115</classIRI>
<classLabel>regulation of abscisic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of abscisic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010116</classIRI>
<classLabel>positive regulation of abscisic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of abscisic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061719</classIRI>
<classLabel>glucose catabolic process to pyruvate utilizing ADP</classLabel>
<newAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to pyruvate utilizing ADP&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ADP-specific glucokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;</newAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061721</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)</classLabel>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;3-sulfolactaldehyde reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061720</classIRI>
<classLabel>6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde</classLabel>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;6-deoxy-6-sulfofructose-1-phosphate aldolase activity&apos;</newAxiom>
<newAxiom>&apos;6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sulfoquinovose isomerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061725</classIRI>
<classLabel>cytosolic lipolysis</classLabel>
<deletedAxiom>&apos;cytosolic lipolysis&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cytosolic lipolysis&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061729</classIRI>
<classLabel>GDP-mannose biosynthetic process from fructose-6-phosphate</classLabel>
<newAxiom>&apos;GDP-mannose biosynthetic process from fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose-6-phosphate isomerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061728</classIRI>
<classLabel>GDP-mannose biosynthetic process from mannose</classLabel>
<newAxiom>&apos;GDP-mannose biosynthetic process from mannose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061705</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate through glucose and fructose</classLabel>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose-6-phosphate isomerase activity&apos;</newAxiom>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sucrose alpha-glucosidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061706</classIRI>
<classLabel>glycolytic process from sucrose through glucose and fructose</classLabel>
<newAxiom>&apos;glycolytic process from sucrose through glucose and fructose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;sucrose catabolic process to fructose-6-phosphate through glucose and fructose&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097713</classIRI>
<classLabel>dolichol-phosphate-mannose synthase regulator activity</classLabel>
<newAxiom>&apos;dolichol-phosphate-mannose synthase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;dolichyl-phosphate-mannose-protein mannosyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061762</classIRI>
<classLabel>CAMKK-AMPK signaling cascade</classLabel>
<newAxiom>&apos;CAMKK-AMPK signaling cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;AMP-activated protein kinase activity&apos;</newAxiom>
<newAxiom>&apos;CAMKK-AMPK signaling cascade&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;calcium ion binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010191</classIRI>
<classLabel>mucilage metabolic process</classLabel>
<deletedAxiom>&apos;mucilage metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;mucilage metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010192</classIRI>
<classLabel>mucilage biosynthetic process</classLabel>
<deletedAxiom>&apos;mucilage biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;mucilage biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061739</classIRI>
<classLabel>protein lipidation involved in autophagosome assembly</classLabel>
<newAxiom>&apos;protein lipidation involved in autophagosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Atg8-family ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046184</classIRI>
<classLabel>aldehyde biosynthetic process</classLabel>
<deletedAxiom>&apos;aldehyde biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;aldehyde biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061781</classIRI>
<classLabel>mitotic cohesin unloading</classLabel>
<deletedAxiom>&apos;mitotic cohesin unloading&apos; SubClassOf &apos;cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic cohesin unloading&apos; EquivalentTo &apos;cohesin unloading&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cell cycle&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061780</classIRI>
<classLabel>mitotic cohesin loading</classLabel>
<deletedAxiom>&apos;mitotic cohesin loading&apos; EquivalentTo &apos;cohesin loading&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;mitotic cell cycle&apos;)</deletedAxiom>
<deletedAxiom>&apos;mitotic cohesin loading&apos; SubClassOf &apos;cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;establishment of mitotic sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;mitotic cohesin loading&apos; SubClassOf &apos;mitotic cell cycle process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046185</classIRI>
<classLabel>aldehyde catabolic process</classLabel>
<deletedAxiom>&apos;aldehyde catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;aldehyde catabolic process&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061774</classIRI>
<classLabel>cohesin unloading</classLabel>
<deletedAxiom>&apos;cohesin unloading&apos; SubClassOf &apos;negative regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;cohesin unloading&apos; SubClassOf &apos;negative regulation of sister chromatid cohesion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097690</classIRI>
<classLabel>iron ion transmembrane transporter inhibitor activity</classLabel>
<newAxiom>&apos;iron ion transmembrane transporter inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;iron ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000774</classIRI>
<classLabel>adenyl-nucleotide exchange factor activity</classLabel>
<newAxiom>&apos;adenyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ATP binding&apos;</newAxiom>
<newAxiom>&apos;adenyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ADP binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009051</classIRI>
<classLabel>pentose-phosphate shunt, oxidative branch</classLabel>
<newAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose-6-phosphate dehydrogenase activity&apos;</newAxiom>
<newAxiom>&apos;pentose-phosphate shunt, oxidative branch&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phosphogluconate dehydrogenase (decarboxylating) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009059</classIRI>
<classLabel>macromolecule biosynthetic process</classLabel>
<deletedAxiom>&apos;macromolecule biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;macromolecule biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009062</classIRI>
<classLabel>fatty acid catabolic process</classLabel>
<deletedAxiom>&apos;fatty acid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;fatty acid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061633</classIRI>
<classLabel>transport-coupled glycolytic process through glucose-6-phosphate</classLabel>
<newAxiom>&apos;transport-coupled glycolytic process through glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061632</classIRI>
<classLabel>RNA lariat debranching enzyme activator activity</classLabel>
<newAxiom>&apos;RNA lariat debranching enzyme activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA lariat debranching enzyme activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061613</classIRI>
<classLabel>glycolytic process from glycerol</classLabel>
<newAxiom>&apos;glycolytic process from glycerol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol to glycerone phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061612</classIRI>
<classLabel>galactose to glucose-1-phosphate metabolic process</classLabel>
<newAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;UTP:galactose-1-phosphate uridylyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;galactose to glucose-1-phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;galactokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061611</classIRI>
<classLabel>mannose to fructose-6-phosphate catabolic process</classLabel>
<newAxiom>&apos;mannose to fructose-6-phosphate catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannokinase activity&apos;</newAxiom>
<newAxiom>&apos;mannose to fructose-6-phosphate catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose-6-phosphate isomerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061610</classIRI>
<classLabel>glycerol to glycerone phosphate metabolic process</classLabel>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol-3-phosphate dehydrogenase (NAD+) activity&apos;</newAxiom>
<newAxiom>&apos;glycerol to glycerone phosphate metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycerol kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061616</classIRI>
<classLabel>glycolytic process from fructose through fructose-6-phosphate</classLabel>
<newAxiom>&apos;glycolytic process from fructose through fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fructokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061619</classIRI>
<classLabel>glycolytic process from mannose through fructose-6-phosphate</classLabel>
<newAxiom>&apos;glycolytic process from mannose through fructose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;mannose to fructose-6-phosphate catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061624</classIRI>
<classLabel>fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate</classLabel>
<newAxiom>&apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ketohexokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061623</classIRI>
<classLabel>glycolytic process from galactose</classLabel>
<newAxiom>&apos;glycolytic process from galactose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;galactose to glucose-1-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<newAxiom>&apos;canonical glycolysis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucokinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061625</classIRI>
<classLabel>glycolytic process through fructose-1-phosphate</classLabel>
<newAxiom>&apos;glycolytic process through fructose-1-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061681</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-phosphogluconate aldolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061680</classIRI>
<classLabel>Entner-Doudoroff pathway through gluconate to D-glyceraldehyde</classLabel>
<newAxiom>&apos;Entner-Doudoroff pathway through gluconate to D-glyceraldehyde&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;2-dehydro-3-deoxy-D-gluconate aldolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061684</classIRI>
<classLabel>chaperone-mediated autophagy</classLabel>
<newAxiom>&apos;chaperone-mediated autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein-folding chaperone binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061688</classIRI>
<classLabel>glycolytic process via Entner-Doudoroff Pathway</classLabel>
<newAxiom>&apos;glycolytic process via Entner-Doudoroff Pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Entner-Doudoroff pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000295</classIRI>
<classLabel>regulation of hydrogen peroxide catabolic process</classLabel>
<deletedAxiom>&apos;regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000296</classIRI>
<classLabel>negative regulation of hydrogen peroxide catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034084</classIRI>
<classLabel>steryl deacetylase activity</classLabel>
<newAxiom>&apos;steryl deacetylase activity&apos; SubClassOf &apos;hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061575</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase activator activity</classLabel>
<newAxiom>&apos;cyclin-dependent protein serine/threonine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000225</classIRI>
<classLabel>negative regulation of testosterone biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of testosterone biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000212</classIRI>
<classLabel>negative regulation of glutamate metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glutamate metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000215</classIRI>
<classLabel>negative regulation of proline metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of proline metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000216</classIRI>
<classLabel>positive regulation of proline metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of proline metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000213</classIRI>
<classLabel>positive regulation of glutamate metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glutamate metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036521</classIRI>
<classLabel>modulation by symbiont of host protein localization to phagocytic vesicle</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host protein localization to phagocytic vesicle&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036522</classIRI>
<classLabel>negative regulation by symbiont of host protein localization to phagocytic vesicle</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host protein localization to phagocytic vesicle&apos; SubClassOf &apos;negative regulation of protein localization to phagocytic vesicle&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host protein localization to phagocytic vesicle&apos; SubClassOf &apos;modulation by symbiont of host protein localization to phagocytic vesicle&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host protein localization to phagocytic vesicle&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061483</classIRI>
<classLabel>sulfinylpropanyl adenylate synthase</classLabel>
<deletedAxiom>&apos;sulfinylpropanyl adenylate synthase&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061463</classIRI>
<classLabel>O-acetyl-ADP-ribose deacetylase activity</classLabel>
<newAxiom>&apos;O-acetyl-ADP-ribose deacetylase activity&apos; SubClassOf &apos;carboxylic ester hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0012501</classIRI>
<classLabel>programmed cell death</classLabel>
<newAxiom>&apos;programmed cell death&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;signal transduction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120292</classIRI>
<classLabel>positive regulation of mitotic recombination-dependent replication fork processing</classLabel>
<newAxiom>&apos;positive regulation of mitotic recombination-dependent replication fork processing&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120291</classIRI>
<classLabel>negative regulation of mitotic recombination-dependent replication fork processing</classLabel>
<newAxiom>&apos;negative regulation of mitotic recombination-dependent replication fork processing&apos; SubClassOf &apos;negative regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036443</classIRI>
<classLabel>dermatan 6-sulfotransferase activity</classLabel>
<deletedAxiom>&apos;dermatan 6-sulfotransferase activity&apos; SubClassOf &apos;sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120215</classIRI>
<classLabel>positive regulation of histidine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of histidine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120214</classIRI>
<classLabel>negative regulation of histidine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of histidine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036487</classIRI>
<classLabel>nitric-oxide synthase inhibitor activity</classLabel>
<newAxiom>&apos;nitric-oxide synthase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nitric-oxide synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036479</classIRI>
<classLabel>peroxidase inhibitor activity</classLabel>
<newAxiom>&apos;peroxidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;peroxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036478</classIRI>
<classLabel>L-dopa decarboxylase activator activity</classLabel>
<newAxiom>&apos;L-dopa decarboxylase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;L-dopa decarboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036470</classIRI>
<classLabel>tyrosine 3-monooxygenase activator activity</classLabel>
<newAxiom>&apos;tyrosine 3-monooxygenase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;tyrosine 3-monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120213</classIRI>
<classLabel>regulation of histidine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of histidine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of histidine biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097354</classIRI>
<classLabel>prenylation</classLabel>
<deletedAxiom>&apos;prenylation&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;prenylation&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097384</classIRI>
<classLabel>cellular lipid biosynthetic process</classLabel>
<deletedAxiom>&apos;cellular lipid biosynthetic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular lipid biosynthetic process&apos; SubClassOf &apos;lipid biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048311</classIRI>
<classLabel>mitochondrion distribution</classLabel>
<deletedAxiom>&apos;mitochondrion distribution&apos; SubClassOf &apos;mitochondrion organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097200</classIRI>
<classLabel>cysteine-type endopeptidase activity involved in execution phase of apoptosis</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; EquivalentTo &apos;cysteine-type endopeptidase activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;execution phase of apoptosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000376</classIRI>
<classLabel>positive regulation of oxygen metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of oxygen metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of oxygen metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000377</classIRI>
<classLabel>regulation of reactive oxygen species metabolic process</classLabel>
<deletedAxiom>&apos;regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000374</classIRI>
<classLabel>regulation of oxygen metabolic process</classLabel>
<deletedAxiom>&apos;regulation of oxygen metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of oxygen metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000375</classIRI>
<classLabel>negative regulation of oxygen metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of oxygen metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of oxygen metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000378</classIRI>
<classLabel>negative regulation of reactive oxygen species metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000379</classIRI>
<classLabel>positive regulation of reactive oxygen species metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of reactive oxygen species metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048270</classIRI>
<classLabel>methionine adenosyltransferase regulator activity</classLabel>
<newAxiom>&apos;methionine adenosyltransferase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;methionine adenosyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097296</classIRI>
<classLabel>activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120083</classIRI>
<classLabel>rough endoplasmic reticulum cisterna</classLabel>
<newAxiom>&apos;rough endoplasmic reticulum cisterna&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;rough endoplasmic reticulum&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160159</classIRI>
<classLabel>positive regulation of N-acetylmuramic acid catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of N-acetylmuramic acid catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of N-acetylmuramic acid catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160186</classIRI>
<classLabel>phospholipase C inhibitor activity</classLabel>
<newAxiom>&apos;phospholipase C inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase C activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160185</classIRI>
<classLabel>phospholipase C activator activity</classLabel>
<newAxiom>&apos;phospholipase C activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phospholipase C activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160193</classIRI>
<classLabel>L-lactate dehydrogenase inhibitor activity</classLabel>
<newAxiom>&apos;L-lactate dehydrogenase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;L-lactate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990001</classIRI>
<classLabel>inhibition of cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;inhibition of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;inhibition of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;inhibition of cysteine-type endopeptidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061135</classIRI>
<classLabel>endopeptidase regulator activity</classLabel>
<newAxiom>&apos;endopeptidase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061134</classIRI>
<classLabel>peptidase regulator activity</classLabel>
<newAxiom>&apos;peptidase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;peptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061133</classIRI>
<classLabel>endopeptidase activator activity</classLabel>
<newAxiom>&apos;endopeptidase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000644</classIRI>
<classLabel>regulation of receptor catabolic process</classLabel>
<deletedAxiom>&apos;regulation of receptor catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of receptor catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000645</classIRI>
<classLabel>negative regulation of receptor catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of receptor catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of receptor catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000646</classIRI>
<classLabel>positive regulation of receptor catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of receptor catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of receptor catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097199</classIRI>
<classLabel>cysteine-type endopeptidase activity involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; EquivalentTo &apos;cysteine-type endopeptidase activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apoptotic signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000609</classIRI>
<classLabel>regulation of thyroid hormone generation</classLabel>
<deletedAxiom>&apos;regulation of thyroid hormone generation&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904025</classIRI>
<classLabel>positive regulation of glucose catabolic process to lactate via pyruvate</classLabel>
<deletedAxiom>&apos;positive regulation of glucose catabolic process to lactate via pyruvate&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000611</classIRI>
<classLabel>positive regulation of thyroid hormone generation</classLabel>
<deletedAxiom>&apos;positive regulation of thyroid hormone generation&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000610</classIRI>
<classLabel>negative regulation of thyroid hormone generation</classLabel>
<deletedAxiom>&apos;negative regulation of thyroid hormone generation&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097153</classIRI>
<classLabel>cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;cysteine-type endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cysteine-type endopeptidase activity involved in apoptotic process&apos; EquivalentTo &apos;cysteine-type endopeptidase activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apoptotic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160206</classIRI>
<classLabel>tRNA (cytidine(32)/uridine(32)-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine(32)/uridine(32)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine(32)/uridine(32)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (uridine) methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine(32)/uridine(32)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytidine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990162</classIRI>
<classLabel>histone H3K4 deacetylase activity</classLabel>
<newAxiom>&apos;histone H3K4 deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141221</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051767</classIRI>
<classLabel>nitric-oxide synthase biosynthetic process</classLabel>
<deletedAxiom>&apos;nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051769</classIRI>
<classLabel>regulation of nitric-oxide synthase biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nitric-oxide synthase biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of nitric-oxide synthase biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;nitric-oxide synthase biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051771</classIRI>
<classLabel>negative regulation of nitric-oxide synthase biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nitric-oxide synthase biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nitric-oxide synthase biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;nitric-oxide synthase biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;negative regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;regulation of nitric-oxide synthase biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051770</classIRI>
<classLabel>positive regulation of nitric-oxide synthase biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;regulation of nitric-oxide synthase biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nitric-oxide synthase biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;nitric-oxide synthase biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf &apos;positive regulation of macromolecule biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of nitric-oxide synthase biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;nitric-oxide synthase biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990119</classIRI>
<classLabel>RNA helicase inhibitor activity</classLabel>
<newAxiom>&apos;RNA helicase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA helicase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048018</classIRI>
<classLabel>receptor ligand activity</classLabel>
<deletedAxiom>&apos;receptor ligand activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099602</classIRI>
<classLabel>neurotransmitter receptor regulator activity</classLabel>
<newAxiom>&apos;neurotransmitter receptor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;neurotransmitter receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085033</classIRI>
<classLabel>symbiont-mediated activation of host NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host NF-kappaB cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;canonical NF-kappaB signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085032</classIRI>
<classLabel>symbiont-mediated perturbation of host NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host NF-kappaB cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;canonical NF-kappaB signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0085034</classIRI>
<classLabel>symbiont-mediated suppression of host NF-kappaB cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host NF-kappaB cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;canonical NF-kappaB signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host NF-kappaB cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000541</classIRI>
<classLabel>positive regulation of protein geranylgeranylation</classLabel>
<deletedAxiom>&apos;positive regulation of protein geranylgeranylation&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000540</classIRI>
<classLabel>negative regulation of protein geranylgeranylation</classLabel>
<deletedAxiom>&apos;negative regulation of protein geranylgeranylation&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904142</classIRI>
<classLabel>negative regulation of carotenoid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of carotenoid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904143</classIRI>
<classLabel>positive regulation of carotenoid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of carotenoid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097027</classIRI>
<classLabel>ubiquitin-protein transferase activator activity</classLabel>
<newAxiom>&apos;ubiquitin-protein transferase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ubiquitin-protein transferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000942</classIRI>
<classLabel>regulation of amylopectin metabolic process</classLabel>
<deletedAxiom>&apos;regulation of amylopectin metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000945</classIRI>
<classLabel>regulation of amylopectin catabolic process</classLabel>
<deletedAxiom>&apos;regulation of amylopectin catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of amylopectin catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000943</classIRI>
<classLabel>negative regulation of amylopectin metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of amylopectin metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000944</classIRI>
<classLabel>positive regulation of amylopectin metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of amylopectin metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036008</classIRI>
<classLabel>sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate</classLabel>
<newAxiom>&apos;sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990216</classIRI>
<classLabel>symbiont-mediated activation of host transcription</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host transcription&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA-templated transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host transcription&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host transcription&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;DNA-templated transcription&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated activation of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990215</classIRI>
<classLabel>symbiont-mediated perturbation of host vesicle-mediated transport</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host vesicle-mediated transport&apos; SubClassOf &apos;symbiont-mediated perturbation of host intracellular transport&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host vesicle-mediated transport&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000045</classIRI>
<classLabel>autophagosome assembly</classLabel>
<newAxiom>&apos;autophagosome assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;Atg1/ULK1 kinase complex assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904219</classIRI>
<classLabel>positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity</classLabel>
<deletedAxiom>&apos;positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos; SubClassOf &apos;regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos; SubClassOf &apos;positive regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;CDP-diacylglycerol-serine O-phosphatidyltransferase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904252</classIRI>
<classLabel>negative regulation of bile acid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of bile acid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904251</classIRI>
<classLabel>regulation of bile acid metabolic process</classLabel>
<deletedAxiom>&apos;regulation of bile acid metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904253</classIRI>
<classLabel>positive regulation of bile acid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of bile acid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904255</classIRI>
<classLabel>negative regulation of iron ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of iron ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of iron ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of iron ion transmembrane transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;iron ion transmembrane transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of iron ion transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;iron ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of iron ion transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of iron ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of iron ion transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002630</classIRI>
<classLabel>positive regulation of proteolysis associated with antigen processing and presentation</classLabel>
<deletedAxiom>&apos;positive regulation of proteolysis associated with antigen processing and presentation&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002629</classIRI>
<classLabel>negative regulation of proteolysis associated with antigen processing and presentation</classLabel>
<deletedAxiom>&apos;negative regulation of proteolysis associated with antigen processing and presentation&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000875</classIRI>
<classLabel>negative regulation of glyoxylate cycle</classLabel>
<deletedAxiom>&apos;negative regulation of glyoxylate cycle&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000876</classIRI>
<classLabel>positive regulation of glyoxylate cycle</classLabel>
<deletedAxiom>&apos;positive regulation of glyoxylate cycle&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000874</classIRI>
<classLabel>regulation of glyoxylate cycle</classLabel>
<newAxiom>&apos;regulation of glyoxylate cycle&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051499</classIRI>
<classLabel>D-aminoacyl-tRNA deacylase activity</classLabel>
<newAxiom>&apos;D-aminoacyl-tRNA deacylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0160215</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000772</classIRI>
<classLabel>regulation of cellular senescence</classLabel>
<deletedAxiom>&apos;regulation of cellular senescence&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cellular senescence&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000773</classIRI>
<classLabel>negative regulation of cellular senescence</classLabel>
<deletedAxiom>&apos;negative regulation of cellular senescence&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cellular senescence&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000777</classIRI>
<classLabel>positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia</classLabel>
<deletedAxiom>&apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to hypoxia&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia&apos; SubClassOf &apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia&apos; EquivalentTo &apos;positive regulation of proteasomal ubiquitin-dependent protein catabolic process&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular response to hypoxia&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000774</classIRI>
<classLabel>positive regulation of cellular senescence</classLabel>
<deletedAxiom>&apos;positive regulation of cellular senescence&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cellular senescence&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000752</classIRI>
<classLabel>regulation of glucosylceramide catabolic process</classLabel>
<deletedAxiom>&apos;regulation of glucosylceramide catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000753</classIRI>
<classLabel>positive regulation of glucosylceramide catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glucosylceramide catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905827</classIRI>
<classLabel>positive regulation of selenocysteine metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of selenocysteine metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905825</classIRI>
<classLabel>regulation of selenocysteine metabolic process</classLabel>
<newAxiom>&apos;regulation of selenocysteine metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905826</classIRI>
<classLabel>negative regulation of selenocysteine metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of selenocysteine metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905724</classIRI>
<classLabel>positive regulation of trypanothione biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905722</classIRI>
<classLabel>regulation of trypanothione biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905723</classIRI>
<classLabel>negative regulation of trypanothione biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of trypanothione biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905775</classIRI>
<classLabel>negative regulation of DNA helicase activity</classLabel>
<deletedAxiom>&apos;negative regulation of DNA helicase activity&apos; SubClassOf &apos;regulation of DNA helicase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA helicase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA helicase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA helicase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA helicase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA helicase activity&apos; SubClassOf &apos;negative regulation of helicase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA helicase activity&apos; SubClassOf &apos;negative regulation of DNA duplex unwinding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903196</classIRI>
<classLabel>negative regulation of L-dopa biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903195</classIRI>
<classLabel>regulation of L-dopa biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903197</classIRI>
<classLabel>positive regulation of L-dopa biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of L-dopa biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170005</classIRI>
<classLabel>cyclic nucleotide phosphodiesterase activator activity</classLabel>
<newAxiom>&apos;cyclic nucleotide phosphodiesterase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cyclic-nucleotide phosphodiesterase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170008</classIRI>
<classLabel>mRNA phosphatase activator activity</classLabel>
<newAxiom>&apos;mRNA phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mRNA 5&apos;-triphosphate monophosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170054</classIRI>
<classLabel>ribonuclease activator activity</classLabel>
<newAxiom>&apos;ribonuclease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA nuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170053</classIRI>
<classLabel>nuclease activator activity</classLabel>
<newAxiom>&apos;nuclease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;nuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903248</classIRI>
<classLabel>regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of citrulline biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of citrulline biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903249</classIRI>
<classLabel>negative regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of citrulline biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903221</classIRI>
<classLabel>regulation of mitotic recombination-dependent replication fork processing</classLabel>
<newAxiom>&apos;regulation of mitotic recombination-dependent replication fork processing&apos; SubClassOf &apos;regulation of cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903280</classIRI>
<classLabel>negative regulation of calcium:sodium antiporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of calcium:sodium antiporter activity&apos; SubClassOf &apos;regulation of calcium:sodium antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcium:sodium antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcium:sodium antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcium:sodium antiporter activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcium:sodium antiporter activity&apos; SubClassOf &apos;negative regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcium:sodium antiporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcium:sodium antiporter activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903285</classIRI>
<classLabel>positive regulation of hydrogen peroxide catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of hydrogen peroxide catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903250</classIRI>
<classLabel>positive regulation of citrulline biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of citrulline biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903266</classIRI>
<classLabel>regulation of ornithine catabolic process</classLabel>
<deletedAxiom>&apos;regulation of ornithine catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ornithine catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903268</classIRI>
<classLabel>positive regulation of ornithine catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of ornithine catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ornithine catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903267</classIRI>
<classLabel>negative regulation of ornithine catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of ornithine catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ornithine catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110051</classIRI>
<classLabel>metabolite repair</classLabel>
<deletedAxiom>&apos;metabolite repair&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;metabolite repair&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004857</classIRI>
<classLabel>enzyme inhibitor activity</classLabel>
<newAxiom>&apos;enzyme inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004858</classIRI>
<classLabel>dUTP pyrophosphatase inhibitor activity</classLabel>
<newAxiom>&apos;dUTP pyrophosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;dUTP diphosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004859</classIRI>
<classLabel>phospholipase inhibitor activity</classLabel>
<newAxiom>&apos;phospholipase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004860</classIRI>
<classLabel>protein kinase inhibitor activity</classLabel>
<newAxiom>&apos;protein kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004861</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase inhibitor activity</classLabel>
<newAxiom>&apos;cyclin-dependent protein serine/threonine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004862</classIRI>
<classLabel>cAMP-dependent protein kinase inhibitor activity</classLabel>
<newAxiom>&apos;cAMP-dependent protein kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cAMP-dependent protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004864</classIRI>
<classLabel>protein phosphatase inhibitor activity</classLabel>
<newAxiom>&apos;protein phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004865</classIRI>
<classLabel>protein serine/threonine phosphatase inhibitor activity</classLabel>
<newAxiom>&apos;protein serine/threonine phosphatase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein serine/threonine phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004866</classIRI>
<classLabel>endopeptidase inhibitor activity</classLabel>
<newAxiom>&apos;endopeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004867</classIRI>
<classLabel>serine-type endopeptidase inhibitor activity</classLabel>
<newAxiom>&apos;serine-type endopeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;serine-type endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004869</classIRI>
<classLabel>cysteine-type endopeptidase inhibitor activity</classLabel>
<newAxiom>&apos;cysteine-type endopeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004883</classIRI>
<classLabel>nuclear glucocorticoid receptor activity</classLabel>
<deletedAxiom>&apos;nuclear glucocorticoid receptor activity&apos; SubClassOf &apos;nuclear steroid receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear glucocorticoid receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;glucocorticoid mediated signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;nuclear glucocorticoid receptor activity&apos; SubClassOf &apos;nuclear receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075135</classIRI>
<classLabel>symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated perturbation of host calcium or calmodulin-mediated signal transduction&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host calcium or calmodulin-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038184</classIRI>
<classLabel>adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway</classLabel>
<newAxiom>&apos;adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled bile acid receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075133</classIRI>
<classLabel>symbiont-mediated perturbation of host calcium or calmodulin-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host calcium or calmodulin-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated perturbation of host signal transduction pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099104</classIRI>
<classLabel>potassium channel activator activity</classLabel>
<newAxiom>&apos;potassium channel activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038185</classIRI>
<classLabel>nuclear receptor-mediated bile acid signaling pathway</classLabel>
<newAxiom>&apos;nuclear receptor-mediated bile acid signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;bile acid nuclear receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099103</classIRI>
<classLabel>channel activator activity</classLabel>
<newAxiom>&apos;channel activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099106</classIRI>
<classLabel>ion channel regulator activity</classLabel>
<newAxiom>&apos;ion channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075118</classIRI>
<classLabel>symbiont-mediated perturbation of host G protein-coupled receptor signal transduction pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host G protein-coupled receptor signal transduction pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051175</classIRI>
<classLabel>negative regulation of sulfur metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of sulfur metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of sulfur metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075120</classIRI>
<classLabel>symbiont-mediated suppression of host G protein-coupled receptor signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host G protein-coupled receptor signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host G protein-coupled receptor signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051174</classIRI>
<classLabel>regulation of phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of phosphorus metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051176</classIRI>
<classLabel>positive regulation of sulfur metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of sulfur metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of sulfur metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038171</classIRI>
<classLabel>cannabinoid signaling pathway</classLabel>
<newAxiom>&apos;cannabinoid signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;cannabinoid receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0075071</classIRI>
<classLabel>symbiont-mediated perturbation of host autophagy</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;autophagy&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004740</classIRI>
<classLabel>pyruvate dehydrogenase (acetyl-transferring) kinase activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (acetyl-transferring) kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate dehydrogenase (acetyl-transferring) kinase activity&apos; SubClassOf &apos;protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903455</classIRI>
<classLabel>negative regulation of androst-4-ene-3,17-dione biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of androst-4-ene-3,17-dione biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903456</classIRI>
<classLabel>positive regulation of androst-4-ene-3,17-dione biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of androst-4-ene-3,17-dione biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903461</classIRI>
<classLabel>Okazaki fragment processing involved in mitotic DNA replication</classLabel>
<newAxiom>&apos;Okazaki fragment processing involved in mitotic DNA replication&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903469</classIRI>
<classLabel>removal of RNA primer involved in mitotic DNA replication</classLabel>
<newAxiom>&apos;removal of RNA primer involved in mitotic DNA replication&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051043</classIRI>
<classLabel>regulation of membrane protein ectodomain proteolysis</classLabel>
<deletedAxiom>&apos;regulation of membrane protein ectodomain proteolysis&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051045</classIRI>
<classLabel>negative regulation of membrane protein ectodomain proteolysis</classLabel>
<deletedAxiom>&apos;negative regulation of membrane protein ectodomain proteolysis&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051044</classIRI>
<classLabel>positive regulation of membrane protein ectodomain proteolysis</classLabel>
<deletedAxiom>&apos;positive regulation of membrane protein ectodomain proteolysis&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0038054</classIRI>
<classLabel>G protein-coupled estrogen receptor activity</classLabel>
<deletedAxiom>&apos;G protein-coupled estrogen receptor activity&apos; SubClassOf &apos;nuclear estrogen receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903591</classIRI>
<classLabel>negative regulation of lysozyme activity</classLabel>
<deletedAxiom>&apos;negative regulation of lysozyme activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;lysozyme activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lysozyme activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;lysozyme activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lysozyme activity&apos; SubClassOf &apos;negative regulation of hydrolase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lysozyme activity&apos; SubClassOf &apos;regulation of lysozyme activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102992</classIRI>
<classLabel>2-methylbutyronitrile hydroxylase activity</classLabel>
<deletedAxiom>&apos;2-methylbutyronitrile hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102989</classIRI>
<classLabel>5-pentadecatrienylresorcinol synthase activity</classLabel>
<deletedAxiom>&apos;5-pentadecatrienylresorcinol synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102951</classIRI>
<classLabel>indole-3-acetyl-phenylalanine synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-phenylalanine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102950</classIRI>
<classLabel>indole-3-acetyl-valine synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-valine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102940</classIRI>
<classLabel>phloroglucinol O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;phloroglucinol O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102941</classIRI>
<classLabel>3,5-dihydroxyanisole O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3,5-dihydroxyanisole O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102942</classIRI>
<classLabel>3,5-dimethoxyphenol O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3,5-dimethoxyphenol O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102939</classIRI>
<classLabel>3-methoxy-5-hydroxytoluene O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;3-methoxy-5-hydroxytoluene O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102972</classIRI>
<classLabel>gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)</classLabel>
<deletedAxiom>&apos;gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016504</classIRI>
<classLabel>peptidase activator activity</classLabel>
<newAxiom>&apos;peptidase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;peptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102910</classIRI>
<classLabel>dirigent protein activity</classLabel>
<deletedAxiom>&apos;dirigent protein activity&apos; SubClassOf &apos;oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;dirigent protein activity&apos; SubClassOf &apos;molecular_function&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102907</classIRI>
<classLabel>sesquisabinene synthase activity</classLabel>
<deletedAxiom>&apos;sesquisabinene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102900</classIRI>
<classLabel>dehydroabietadienal hydroxylase activity</classLabel>
<deletedAxiom>&apos;dehydroabietadienal hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102901</classIRI>
<classLabel>isopimaradienol hydroxylase activity</classLabel>
<deletedAxiom>&apos;isopimaradienol hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102902</classIRI>
<classLabel>isopimaradienal hydroxylase activity</classLabel>
<deletedAxiom>&apos;isopimaradienal hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016538</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase regulator activity</classLabel>
<newAxiom>&apos;cyclin-dependent protein serine/threonine kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclin-dependent protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102929</classIRI>
<classLabel>lachrymatory factor synthase activity</classLabel>
<deletedAxiom>&apos;lachrymatory factor synthase activity&apos; SubClassOf &apos;intramolecular oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102924</classIRI>
<classLabel>gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102911</classIRI>
<classLabel>(-)-secoisolariciresinol dehydrogenase activity</classLabel>
<deletedAxiom>&apos;(-)-secoisolariciresinol dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102912</classIRI>
<classLabel>(-)-lactol dehydrogenase activity</classLabel>
<deletedAxiom>&apos;(-)-lactol dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102914</classIRI>
<classLabel>N-methyl-3-aminomethylindole N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;N-methyl-3-aminomethylindole N-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903653</classIRI>
<classLabel>symbiont-mediated perturbation of host cell motility</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host cell motility&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell motility&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901003</classIRI>
<classLabel>negative regulation of fermentation</classLabel>
<deletedAxiom>&apos;negative regulation of fermentation&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of fermentation&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016483</classIRI>
<classLabel>tryptophan hydroxylase activator activity</classLabel>
<newAxiom>&apos;tryptophan hydroxylase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;tryptophan 5-monooxygenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090358</classIRI>
<classLabel>positive regulation of tryptophan metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of tryptophan metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of tryptophan metabolic process&apos; SubClassOf &apos;positive regulation of amine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090357</classIRI>
<classLabel>regulation of tryptophan metabolic process</classLabel>
<newAxiom>&apos;regulation of tryptophan metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of tryptophan metabolic process&apos; SubClassOf &apos;regulation of amine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090359</classIRI>
<classLabel>negative regulation of abscisic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of abscisic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090354</classIRI>
<classLabel>regulation of auxin metabolic process</classLabel>
<deletedAxiom>&apos;regulation of auxin metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090353</classIRI>
<classLabel>polygalacturonase inhibitor activity</classLabel>
<newAxiom>&apos;polygalacturonase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;polygalacturonase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090356</classIRI>
<classLabel>negative regulation of auxin metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of auxin metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090355</classIRI>
<classLabel>positive regulation of auxin metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of auxin metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090352</classIRI>
<classLabel>regulation of nitrate assimilation</classLabel>
<deletedAxiom>&apos;regulation of nitrate assimilation&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090347</classIRI>
<classLabel>regulation of cellular organohalogen metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular organohalogen metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of cellular organohalogen metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090349</classIRI>
<classLabel>negative regulation of cellular organohalogen metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular organohalogen metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cellular organohalogen metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090345</classIRI>
<classLabel>cellular organohalogen metabolic process</classLabel>
<deletedAxiom>&apos;cellular organohalogen metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular organohalogen metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090398</classIRI>
<classLabel>cellular senescence</classLabel>
<deletedAxiom>&apos;cellular senescence&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular senescence&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090399</classIRI>
<classLabel>replicative senescence</classLabel>
<deletedAxiom>&apos;replicative senescence&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;replicative senescence&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090382</classIRI>
<classLabel>phagosome maturation</classLabel>
<newAxiom>&apos;phagosome maturation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;exocytosis&apos;</newAxiom>
<newAxiom>&apos;phagosome maturation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;phagolysosome assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102896</classIRI>
<classLabel>colnelenate synthase activity</classLabel>
<deletedAxiom>&apos;colnelenate synthase activity&apos; SubClassOf &apos;hydro-lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102897</classIRI>
<classLabel>abietadienal hydroxylase activity</classLabel>
<deletedAxiom>&apos;abietadienal hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102898</classIRI>
<classLabel>levopimaradienol hydroxylase activity</classLabel>
<deletedAxiom>&apos;levopimaradienol hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102899</classIRI>
<classLabel>dehydroabietadienol hydroxylase activity</classLabel>
<deletedAxiom>&apos;dehydroabietadienol hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102880</classIRI>
<classLabel>isobazzanene synthase activity</classLabel>
<deletedAxiom>&apos;isobazzanene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102886</classIRI>
<classLabel>alpha-chamigrene synthase activity</classLabel>
<deletedAxiom>&apos;alpha-chamigrene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102888</classIRI>
<classLabel>delta-cuprenene synthase activity</classLabel>
<deletedAxiom>&apos;delta-cuprenene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090369</classIRI>
<classLabel>ornithine carbamoyltransferase inhibitor activity</classLabel>
<newAxiom>&apos;ornithine carbamoyltransferase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ornithine carbamoyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090368</classIRI>
<classLabel>regulation of ornithine metabolic process</classLabel>
<newAxiom>&apos;regulation of ornithine metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102827</classIRI>
<classLabel>galactosylononitol-raffinose galactosyltransferase activity</classLabel>
<deletedAxiom>&apos;galactosylononitol-raffinose galactosyltransferase activity&apos; SubClassOf &apos;hexosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102820</classIRI>
<classLabel>norbixin methyltransferase activity</classLabel>
<deletedAxiom>&apos;norbixin methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102821</classIRI>
<classLabel>bixin methyltransferase activity</classLabel>
<deletedAxiom>&apos;bixin methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102817</classIRI>
<classLabel>caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3&apos;-O-glucoside) 3&apos;-O-hydroxycinnamoyltransferase activity</classLabel>
<deletedAxiom>&apos;caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3&apos;-O-glucoside) 3&apos;-O-hydroxycinnamoyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102819</classIRI>
<classLabel>bixin aldehyde dehydrogenase activity</classLabel>
<deletedAxiom>&apos;bixin aldehyde dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102812</classIRI>
<classLabel>4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102814</classIRI>
<classLabel>caffeoyl-CoA:delphinidin-3,5,3&apos;-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity</classLabel>
<deletedAxiom>&apos;caffeoyl-CoA:delphinidin-3,5,3&apos;-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004407</classIRI>
<classLabel>histone deacetylase activity</classLabel>
<deletedAxiom>&apos;histone deacetylase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
<deletedAxiom>&apos;histone deacetylase activity&apos; SubClassOf &apos;histone modifying activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000082</classIRI>
<classLabel>regulation of L-ascorbic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of L-ascorbic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000083</classIRI>
<classLabel>negative regulation of L-ascorbic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of L-ascorbic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of L-ascorbic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102806</classIRI>
<classLabel>4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102800</classIRI>
<classLabel>caffeoyl-CoA:pelargonidin-3,5-diglucoside-6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;caffeoyl-CoA:pelargonidin-3,5-diglucoside-6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903869</classIRI>
<classLabel>negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity</classLabel>
<deletedAxiom>&apos;negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;methylenetetrahydrofolate reductase (NAD(P)H) activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;methylenetetrahydrofolate reductase (NAD(P)H) activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity&apos; SubClassOf &apos;regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031949</classIRI>
<classLabel>regulation of glucocorticoid catabolic process</classLabel>
<deletedAxiom>&apos;regulation of glucocorticoid catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031944</classIRI>
<classLabel>negative regulation of glucocorticoid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glucocorticoid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031943</classIRI>
<classLabel>regulation of glucocorticoid metabolic process</classLabel>
<deletedAxiom>&apos;regulation of glucocorticoid metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031945</classIRI>
<classLabel>positive regulation of glucocorticoid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glucocorticoid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018980</classIRI>
<classLabel>2,4,5-trichlorophenoxyacetic acid metabolic process</classLabel>
<newAxiom>&apos;2,4,5-trichlorophenoxyacetic acid metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000013</classIRI>
<classLabel>regulation of arginine biosynthetic process via ornithine</classLabel>
<deletedAxiom>&apos;regulation of arginine biosynthetic process via ornithine&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004355</classIRI>
<classLabel>glutamate synthase (NADPH) activity</classLabel>
<deletedAxiom>&apos;glutamate synthase (NADPH) activity&apos; SubClassOf &apos;glutamate synthase activity, NAD(P)H as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;glutamate synthase (NADPH) activity&apos; SubClassOf &apos;glutamate synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031951</classIRI>
<classLabel>positive regulation of glucocorticoid catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glucocorticoid catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031950</classIRI>
<classLabel>negative regulation of glucocorticoid catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glucocorticoid catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903787</classIRI>
<classLabel>negative regulation of glutathione biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of glutathione biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glutathione biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903786</classIRI>
<classLabel>regulation of glutathione biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of glutathione biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of glutathione biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903788</classIRI>
<classLabel>positive regulation of glutathione biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of glutathione biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glutathione biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031999</classIRI>
<classLabel>negative regulation of fatty acid beta-oxidation</classLabel>
<deletedAxiom>&apos;negative regulation of fatty acid beta-oxidation&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031998</classIRI>
<classLabel>regulation of fatty acid beta-oxidation</classLabel>
<deletedAxiom>&apos;regulation of fatty acid beta-oxidation&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901167</classIRI>
<classLabel>3-chlorocatechol metabolic process</classLabel>
<newAxiom>&apos;3-chlorocatechol metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090310</classIRI>
<classLabel>negative regulation of DNA methylation-dependent heterochromatin formation</classLabel>
<deletedAxiom>&apos;negative regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf &apos;regulation of DNA methylation-dependent heterochromatin formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090309</classIRI>
<classLabel>positive regulation of DNA methylation-dependent heterochromatin formation</classLabel>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf &apos;positive regulation of heterochromatin formation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA methylation-dependent heterochromatin formation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf &apos;regulation of DNA methylation-dependent heterochromatin formation&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of DNA methylation-dependent heterochromatin formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA methylation-dependent heterochromatin formation&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090308</classIRI>
<classLabel>regulation of DNA methylation-dependent heterochromatin formation</classLabel>
<deletedAxiom>&apos;regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf &apos;regulation of heterochromatin formation&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of DNA methylation-dependent heterochromatin formation&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;DNA methylation-dependent heterochromatin formation&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of DNA methylation-dependent heterochromatin formation&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;DNA methylation-dependent heterochromatin formation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102792</classIRI>
<classLabel>sinapaldehyde:NAD(P)+ oxidoreductase activity</classLabel>
<deletedAxiom>&apos;sinapaldehyde:NAD(P)+ oxidoreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102781</classIRI>
<classLabel>isofucosterol hydroxylase activity</classLabel>
<deletedAxiom>&apos;isofucosterol hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102787</classIRI>
<classLabel>caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102788</classIRI>
<classLabel>4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102782</classIRI>
<classLabel>cholestanol hydroxylase activity</classLabel>
<deletedAxiom>&apos;cholestanol hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090208</classIRI>
<classLabel>positive regulation of triglyceride metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of triglyceride metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090207</classIRI>
<classLabel>regulation of triglyceride metabolic process</classLabel>
<deletedAxiom>&apos;regulation of triglyceride metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090209</classIRI>
<classLabel>negative regulation of triglyceride metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of triglyceride metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102753</classIRI>
<classLabel>chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity</classLabel>
<deletedAxiom>&apos;chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102754</classIRI>
<classLabel>chlorophyllide-b:phytyl-diphosphate phytyltransferase activity</classLabel>
<deletedAxiom>&apos;chlorophyllide-b:phytyl-diphosphate phytyltransferase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102755</classIRI>
<classLabel>gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity</classLabel>
<deletedAxiom>&apos;gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102747</classIRI>
<classLabel>chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity</classLabel>
<deletedAxiom>&apos;chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102743</classIRI>
<classLabel>eriodictyol,NADPH:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;eriodictyol,NADPH:oxygen oxidoreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102739</classIRI>
<classLabel>(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102737</classIRI>
<classLabel>p-coumaroyltriacetic acid synthase activity</classLabel>
<deletedAxiom>&apos;p-coumaroyltriacetic acid synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102738</classIRI>
<classLabel>(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102775</classIRI>
<classLabel>6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity</classLabel>
<deletedAxiom>&apos;6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102774</classIRI>
<classLabel>p-coumaroyltriacetic acid lactone synthase activity</classLabel>
<deletedAxiom>&apos;p-coumaroyltriacetic acid lactone synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102768</classIRI>
<classLabel>anthocyanidin synthase activity</classLabel>
<deletedAxiom>&apos;anthocyanidin synthase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102764</classIRI>
<classLabel>6-deoxotyphasterol C-23 hydroxylase activity</classLabel>
<deletedAxiom>&apos;6-deoxotyphasterol C-23 hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102711</classIRI>
<classLabel>gibberellin A25,oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A25,oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102712</classIRI>
<classLabel>gibberellin A13,oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A13,oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102708</classIRI>
<classLabel>S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102709</classIRI>
<classLabel>S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity&apos; SubClassOf &apos;S-adenosylmethionine-dependent methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903954</classIRI>
<classLabel>positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization</classLabel>
<deletedAxiom>&apos;positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos; SubClassOf &apos;regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos; SubClassOf &apos;positive regulation of voltage-gated potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization&apos; SubClassOf &apos;positive regulation of membrane repolarization during cardiac muscle cell action potential&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006915</classIRI>
<classLabel>apoptotic process</classLabel>
<newAxiom>&apos;apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;apoptotic signaling pathway&apos;</newAxiom>
<newAxiom>&apos;apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;execution phase of apoptosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006914</classIRI>
<classLabel>autophagy</classLabel>
<deletedAxiom>&apos;autophagy&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;transmembrane transport&apos;</newAxiom>
<newAxiom>&apos;autophagy&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006919</classIRI>
<classLabel>activation of cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;activation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018901</classIRI>
<classLabel>2,4-dichlorophenoxyacetic acid metabolic process</classLabel>
<newAxiom>&apos;2,4-dichlorophenoxyacetic acid metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018911</classIRI>
<classLabel>1,2,4-trichlorobenzene catabolic process</classLabel>
<newAxiom>&apos;1,2,4-trichlorobenzene catabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018914</classIRI>
<classLabel>chlorobenzene catabolic process</classLabel>
<newAxiom>&apos;chlorobenzene catabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102730</classIRI>
<classLabel>cathasterone hydroxylase activity</classLabel>
<deletedAxiom>&apos;cathasterone hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903930</classIRI>
<classLabel>regulation of pyrimidine-containing compound salvage</classLabel>
<deletedAxiom>&apos;regulation of pyrimidine-containing compound salvage&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102725</classIRI>
<classLabel>24-methyldesmosterol reductase activity</classLabel>
<deletedAxiom>&apos;24-methyldesmosterol reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102727</classIRI>
<classLabel>3beta-hydroxysteroid dehydrogenase activity</classLabel>
<deletedAxiom>&apos;3beta-hydroxysteroid dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903931</classIRI>
<classLabel>positive regulation of pyrimidine-containing compound salvage</classLabel>
<deletedAxiom>&apos;positive regulation of pyrimidine-containing compound salvage&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018922</classIRI>
<classLabel>iprodione metabolic process</classLabel>
<newAxiom>&apos;iprodione metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102713</classIRI>
<classLabel>gibberellin A25 hydroxylase activity</classLabel>
<deletedAxiom>&apos;gibberellin A25 hydroxylase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102714</classIRI>
<classLabel>gibberellin A12,oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A12,oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102715</classIRI>
<classLabel>gibberellin A17,oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A17,oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102716</classIRI>
<classLabel>gibberellin A28,oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A28,oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006948</classIRI>
<classLabel>induction by virus of host cell-cell fusion</classLabel>
<deletedAxiom>&apos;induction by virus of host cell-cell fusion&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018929</classIRI>
<classLabel>methyl fluoride metabolic process</classLabel>
<newAxiom>&apos;methyl fluoride metabolic process&apos; SubClassOf &apos;cellular organofluorine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018942</classIRI>
<classLabel>organometal metabolic process</classLabel>
<deletedAxiom>&apos;organometal metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;organometal metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018961</classIRI>
<classLabel>pentachlorophenol metabolic process</classLabel>
<newAxiom>&apos;pentachlorophenol metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018873</classIRI>
<classLabel>atrazine metabolic process</classLabel>
<newAxiom>&apos;atrazine metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018881</classIRI>
<classLabel>bromoxynil metabolic process</classLabel>
<newAxiom>&apos;bromoxynil metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018888</classIRI>
<classLabel>3-chloroacrylic acid metabolic process</classLabel>
<newAxiom>&apos;3-chloroacrylic acid metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018889</classIRI>
<classLabel>2-chloro-N-isopropylacetanilide metabolic process</classLabel>
<newAxiom>&apos;2-chloro-N-isopropylacetanilide metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018898</classIRI>
<classLabel>2,4-dichlorobenzoate metabolic process</classLabel>
<newAxiom>&apos;2,4-dichlorobenzoate metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016236</classIRI>
<classLabel>macroautophagy</classLabel>
<newAxiom>&apos;macroautophagy&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;autophagosome assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016230</classIRI>
<classLabel>sphingomyelin phosphodiesterase activator activity</classLabel>
<newAxiom>&apos;sphingomyelin phosphodiesterase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;sphingomyelin phosphodiesterase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016248</classIRI>
<classLabel>channel inhibitor activity</classLabel>
<newAxiom>&apos;channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016247</classIRI>
<classLabel>channel regulator activity</classLabel>
<newAxiom>&apos;channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016289</classIRI>
<classLabel>acyl-CoA hydrolase activity</classLabel>
<newAxiom>&apos;acyl-CoA hydrolase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0160215</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016298</classIRI>
<classLabel>lipase activity</classLabel>
<deletedAxiom>&apos;lipase activity&apos; SubClassOf &apos;carboxylic ester hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;lipase activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102660</classIRI>
<classLabel>caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity</classLabel>
<deletedAxiom>&apos;caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102665</classIRI>
<classLabel>indole-3-acetyl-glutamate synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-glutamate synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102666</classIRI>
<classLabel>indole-3-acetyl-beta-4-D-glucose hydrolase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-beta-4-D-glucose hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102667</classIRI>
<classLabel>indole-3-acetyl-beta-1-D-glucose hydrolase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-beta-1-D-glucose hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102663</classIRI>
<classLabel>gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102664</classIRI>
<classLabel>indole-3-acetyl-leucine synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-leucine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102658</classIRI>
<classLabel>2-oxo-5-methylthiopentanoate aminotransferase activity</classLabel>
<deletedAxiom>&apos;2-oxo-5-methylthiopentanoate aminotransferase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102699</classIRI>
<classLabel>2-methylpropionitrile hydroxylase activity</classLabel>
<deletedAxiom>&apos;2-methylpropionitrile hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102680</classIRI>
<classLabel>campest-4-en-3-one hydroxylase activity</classLabel>
<deletedAxiom>&apos;campest-4-en-3-one hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102681</classIRI>
<classLabel>isoamylase (maltodextrin-releasing) activity</classLabel>
<deletedAxiom>&apos;isoamylase (maltodextrin-releasing) activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102633</classIRI>
<classLabel>flaviolin monooxygenase activity</classLabel>
<deletedAxiom>&apos;flaviolin monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102630</classIRI>
<classLabel>gossypetin 8-methyl ester 3&apos;-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;gossypetin 8-methyl ester 3&apos;-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102631</classIRI>
<classLabel>caffeoylglucose 3-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;caffeoylglucose 3-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102629</classIRI>
<classLabel>patuletin 3&apos;-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;patuletin 3&apos;-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090155</classIRI>
<classLabel>negative regulation of sphingolipid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of sphingolipid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090154</classIRI>
<classLabel>positive regulation of sphingolipid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of sphingolipid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102621</classIRI>
<classLabel>emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity</classLabel>
<deletedAxiom>&apos;emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102622</classIRI>
<classLabel>linuron hydrolase activity</classLabel>
<deletedAxiom>&apos;linuron hydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102620</classIRI>
<classLabel>3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity</classLabel>
<deletedAxiom>&apos;3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102615</classIRI>
<classLabel>ent-cassadiene-C2-hydroxylase activity</classLabel>
<deletedAxiom>&apos;ent-cassadiene-C2-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102650</classIRI>
<classLabel>cyclo-acetoacetyl-L-tryptophan synthetase activity</classLabel>
<deletedAxiom>&apos;cyclo-acetoacetyl-L-tryptophan synthetase activity&apos; SubClassOf &apos;acid-amino acid ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102652</classIRI>
<classLabel>gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102653</classIRI>
<classLabel>gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102647</classIRI>
<classLabel>D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity</classLabel>
<deletedAxiom>&apos;D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity&apos; SubClassOf &apos;transketolase or transaldolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102648</classIRI>
<classLabel>D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity</classLabel>
<deletedAxiom>&apos;D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity&apos; SubClassOf &apos;transketolase or transaldolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102649</classIRI>
<classLabel>acetoacetyl-ACP synthase activity</classLabel>
<deletedAxiom>&apos;acetoacetyl-ACP synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102640</classIRI>
<classLabel>paspalinine synthase activity</classLabel>
<deletedAxiom>&apos;paspalinine synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102639</classIRI>
<classLabel>paspalicine synthase activity</classLabel>
<deletedAxiom>&apos;paspalicine synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901413</classIRI>
<classLabel>regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA</classLabel>
<newAxiom>&apos;regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006805</classIRI>
<classLabel>xenobiotic metabolic process</classLabel>
<deletedAxiom>&apos;xenobiotic metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;xenobiotic metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090180</classIRI>
<classLabel>positive regulation of thiamine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of thiamine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102607</classIRI>
<classLabel>3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity</classLabel>
<deletedAxiom>&apos;3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102608</classIRI>
<classLabel>tetracenomycin B3 8-O-methyl transferase activity</classLabel>
<deletedAxiom>&apos;tetracenomycin B3 8-O-methyl transferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102603</classIRI>
<classLabel>12-demethyl-elloramycin C12a O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;12-demethyl-elloramycin C12a O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102605</classIRI>
<classLabel>cyclooctat-9-en-5,7-diol C18-monooxygenase activity</classLabel>
<deletedAxiom>&apos;cyclooctat-9-en-5,7-diol C18-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102606</classIRI>
<classLabel>octat-9-en-7-ol 5-monooxygenase activity</classLabel>
<deletedAxiom>&apos;octat-9-en-7-ol 5-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102600</classIRI>
<classLabel>cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity</classLabel>
<deletedAxiom>&apos;cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102602</classIRI>
<classLabel>cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity</classLabel>
<deletedAxiom>&apos;cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901466</classIRI>
<classLabel>regulation of ferulate catabolic process</classLabel>
<deletedAxiom>&apos;regulation of ferulate catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ferulate catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of ferulate catabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901467</classIRI>
<classLabel>negative regulation of ferulate catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of ferulate catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ferulate catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901468</classIRI>
<classLabel>positive regulation of ferulate catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of ferulate catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ferulate catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901434</classIRI>
<classLabel>regulation of toluene catabolic process</classLabel>
<deletedAxiom>&apos;regulation of toluene catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of toluene catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901435</classIRI>
<classLabel>negative regulation of toluene catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of toluene catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of toluene catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901436</classIRI>
<classLabel>positive regulation of toluene catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of toluene catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of toluene catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006857</classIRI>
<classLabel>oligopeptide transport</classLabel>
<deletedAxiom>&apos;oligopeptide transport&apos; SubClassOf &apos;amide transport&apos;</deletedAxiom>
<newAxiom>&apos;oligopeptide transport&apos; SubClassOf &apos;peptide transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901351</classIRI>
<classLabel>regulation of phosphatidylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylglycerol biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901352</classIRI>
<classLabel>negative regulation of phosphatidylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylglycerol biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901353</classIRI>
<classLabel>positive regulation of phosphatidylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylglycerol biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006790</classIRI>
<classLabel>sulfur compound metabolic process</classLabel>
<deletedAxiom>&apos;sulfur compound metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;sulfur compound metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006793</classIRI>
<classLabel>phosphorus metabolic process</classLabel>
<deletedAxiom>&apos;phosphorus metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phosphorus metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006799</classIRI>
<classLabel>polyphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;polyphosphate biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;polyphosphate biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043763</classIRI>
<classLabel>UTP:glucose-1-phosphate uridylyltransferase regulator activity</classLabel>
<newAxiom>&apos;UTP:glucose-1-phosphate uridylyltransferase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;UTP:glucose-1-phosphate uridylyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016176</classIRI>
<classLabel>superoxide-generating NADPH oxidase activator activity</classLabel>
<newAxiom>&apos;superoxide-generating NADPH oxidase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;superoxide-generating NADPH oxidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102591</classIRI>
<classLabel>delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity</classLabel>
<deletedAxiom>&apos;delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102592</classIRI>
<classLabel>delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity</classLabel>
<deletedAxiom>&apos;delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102594</classIRI>
<classLabel>cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity</classLabel>
<deletedAxiom>&apos;cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102599</classIRI>
<classLabel>cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity</classLabel>
<deletedAxiom>&apos;cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102595</classIRI>
<classLabel>cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity</classLabel>
<deletedAxiom>&apos;cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102581</classIRI>
<classLabel>cyanidin 3-O-glucoside-p-coumaroyltransferase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3-O-glucoside-p-coumaroyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102582</classIRI>
<classLabel>cyanidin 3-O-p-coumaroylglucoside 2-O&apos;&apos;-xylosyltransferase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3-O-p-coumaroylglucoside 2-O&apos;&apos;-xylosyltransferase activity&apos; SubClassOf &apos;pentosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102583</classIRI>
<classLabel>cyanidin 3-O-glucoside-(2&apos;&apos;-O-xyloside) 6&apos;&apos;-O-acyltransferase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3-O-glucoside-(2&apos;&apos;-O-xyloside) 6&apos;&apos;-O-acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102589</classIRI>
<classLabel>cyanidin 3-O-glucoside 3&apos;&apos;,6&apos;&apos;-O-dimalonyltransferase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3-O-glucoside 3&apos;&apos;,6&apos;&apos;-O-dimalonyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102586</classIRI>
<classLabel>cyanidin 3-O-[2&apos;&apos;-O-(2&apos;&apos;-O-(sinapoyl) xylosyl) 6&apos;&apos;-O-(p-coumaroyl) glucoside] 5-O-[6&apos;&apos;-O-(malonyl) glucoside] sinapoyltransferase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3-O-[2&apos;&apos;-O-(2&apos;&apos;-O-(sinapoyl) xylosyl) 6&apos;&apos;-O-(p-coumaroyl) glucoside] 5-O-[6&apos;&apos;-O-(malonyl) glucoside] sinapoyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102540</classIRI>
<classLabel>D-mannose 6-phosphate 1-epimerase activity</classLabel>
<deletedAxiom>&apos;D-mannose 6-phosphate 1-epimerase activity&apos; SubClassOf &apos;racemase and epimerase activity, acting on carbohydrates and derivatives&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102541</classIRI>
<classLabel>D-galactose 6-phosphate 1-epimerase activity</classLabel>
<deletedAxiom>&apos;D-galactose 6-phosphate 1-epimerase activity&apos; SubClassOf &apos;racemase and epimerase activity, acting on carbohydrates and derivatives&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102537</classIRI>
<classLabel>ecdysone-phosphate phosphatase activity</classLabel>
<deletedAxiom>&apos;ecdysone-phosphate phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102570</classIRI>
<classLabel>tyrosine:phenylpyruvate aminotransferase activity</classLabel>
<deletedAxiom>&apos;tyrosine:phenylpyruvate aminotransferase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102569</classIRI>
<classLabel>FR-33289 synthase activity</classLabel>
<deletedAxiom>&apos;FR-33289 synthase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102563</classIRI>
<classLabel>aurachin C monooxygenase activity</classLabel>
<deletedAxiom>&apos;aurachin C monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102564</classIRI>
<classLabel>aurachin C epoxide hydrolase/isomerase activity</classLabel>
<deletedAxiom>&apos;aurachin C epoxide hydrolase/isomerase activity&apos; SubClassOf &apos;ether hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102508</classIRI>
<classLabel>cyanidin 3,7-diglucoside glucosidase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3,7-diglucoside glucosidase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102509</classIRI>
<classLabel>cyanidin 3,5-diglucoside glucosidase activity</classLabel>
<deletedAxiom>&apos;cyanidin 3,5-diglucoside glucosidase activity&apos; SubClassOf &apos;hydrolase activity, hydrolyzing O-glycosyl compounds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102528</classIRI>
<classLabel>7,8,4&apos;-trihydroxyflavone methyltransferase activity</classLabel>
<deletedAxiom>&apos;7,8,4&apos;-trihydroxyflavone methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102520</classIRI>
<classLabel>L-threonine O-3-phosphate phosphatase activity</classLabel>
<deletedAxiom>&apos;L-threonine O-3-phosphate phosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090073</classIRI>
<classLabel>positive regulation of protein homodimerization activity</classLabel>
<deletedAxiom>&apos;positive regulation of protein homodimerization activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein homodimerization activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein homodimerization activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein homodimerization activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein homodimerization activity&apos; SubClassOf &apos;positive regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of protein homodimerization activity&apos; SubClassOf &apos;regulation of protein homodimerization activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901542</classIRI>
<classLabel>regulation of ent-pimara-8(14),15-diene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of ent-pimara-8(14),15-diene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901543</classIRI>
<classLabel>negative regulation of ent-pimara-8(14),15-diene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of ent-pimara-8(14),15-diene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901544</classIRI>
<classLabel>positive regulation of ent-pimara-8(14),15-diene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of ent-pimara-8(14),15-diene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090045</classIRI>
<classLabel>positive regulation of deacetylase activity</classLabel>
<deletedAxiom>&apos;positive regulation of deacetylase activity&apos; SubClassOf &apos;positive regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of deacetylase activity&apos; SubClassOf &apos;positive regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006700</classIRI>
<classLabel>C21-steroid hormone biosynthetic process</classLabel>
<deletedAxiom>&apos;C21-steroid hormone biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901577</classIRI>
<classLabel>regulation of alkane biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of alkane biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of alkane biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901578</classIRI>
<classLabel>negative regulation of alkane biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of alkane biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of alkane biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901579</classIRI>
<classLabel>positive regulation of alkane biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of alkane biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of alkane biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006720</classIRI>
<classLabel>isoprenoid metabolic process</classLabel>
<deletedAxiom>&apos;isoprenoid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;isoprenoid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006730</classIRI>
<classLabel>one-carbon metabolic process</classLabel>
<deletedAxiom>&apos;one-carbon metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090088</classIRI>
<classLabel>regulation of oligopeptide transport</classLabel>
<deletedAxiom>&apos;regulation of oligopeptide transport&apos; SubClassOf &apos;regulation of transport&apos;</deletedAxiom>
<newAxiom>&apos;regulation of oligopeptide transport&apos; SubClassOf &apos;regulation of peptide transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006631</classIRI>
<classLabel>fatty acid metabolic process</classLabel>
<deletedAxiom>&apos;fatty acid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;fatty acid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006635</classIRI>
<classLabel>fatty acid beta-oxidation</classLabel>
<newAxiom>&apos;fatty acid beta-oxidation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fatty acid ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006638</classIRI>
<classLabel>neutral lipid metabolic process</classLabel>
<deletedAxiom>&apos;neutral lipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;neutral lipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006643</classIRI>
<classLabel>membrane lipid metabolic process</classLabel>
<deletedAxiom>&apos;membrane lipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;membrane lipid metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;membrane&apos;</newAxiom>
<newAxiom>&apos;membrane lipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006644</classIRI>
<classLabel>phospholipid metabolic process</classLabel>
<deletedAxiom>&apos;phospholipid metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phospholipid metabolic process&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006657</classIRI>
<classLabel>CDP-choline pathway</classLabel>
<newAxiom>&apos;CDP-choline pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;choline kinase activity&apos;</newAxiom>
<newAxiom>&apos;CDP-choline pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;diacylglycerol cholinephosphotransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016005</classIRI>
<classLabel>phospholipase A2 activator activity</classLabel>
<newAxiom>&apos;phospholipase A2 activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phospholipase A2 activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016004</classIRI>
<classLabel>phospholipase activator activity</classLabel>
<newAxiom>&apos;phospholipase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phospholipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006696</classIRI>
<classLabel>ergosterol biosynthetic process</classLabel>
<deletedAxiom>&apos;ergosterol biosynthetic process&apos; SubClassOf &apos;cellular lipid biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016040</classIRI>
<classLabel>glutamate synthase (NADH) activity</classLabel>
<deletedAxiom>&apos;glutamate synthase (NADH) activity&apos; SubClassOf &apos;glutamate synthase activity, NAD(P)H as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;glutamate synthase (NADH) activity&apos; SubClassOf &apos;glutamate synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016053</classIRI>
<classLabel>organic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;organic acid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102472</classIRI>
<classLabel>eriodictyol 2-hydroxylase activity</classLabel>
<deletedAxiom>&apos;eriodictyol 2-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102476</classIRI>
<classLabel>pinocembrin 2-hydroxylase activity</classLabel>
<deletedAxiom>&apos;pinocembrin 2-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102466</classIRI>
<classLabel>beta-carotene 2,2&apos;-beta-hydroxylase activity</classLabel>
<deletedAxiom>&apos;beta-carotene 2,2&apos;-beta-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102494</classIRI>
<classLabel>GA20 2,3-desaturase activity</classLabel>
<deletedAxiom>&apos;GA20 2,3-desaturase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102495</classIRI>
<classLabel>GA5 3beta-hydroxylase activity</classLabel>
<deletedAxiom>&apos;GA5 3beta-hydroxylase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102496</classIRI>
<classLabel>GA5 2,3 epoxidase activity</classLabel>
<deletedAxiom>&apos;GA5 2,3 epoxidase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102436</classIRI>
<classLabel>7-methylmyricetin 4&apos;-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;7-methylmyricetin 4&apos;-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102433</classIRI>
<classLabel>phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity</classLabel>
<deletedAxiom>&apos;phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102427</classIRI>
<classLabel>allocryptopine 6-hydroxylase activity</classLabel>
<deletedAxiom>&apos;allocryptopine 6-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102438</classIRI>
<classLabel>laricitrin 4&apos;-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;laricitrin 4&apos;-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102400</classIRI>
<classLabel>dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity</classLabel>
<deletedAxiom>&apos;dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006507</classIRI>
<classLabel>GPI anchor release</classLabel>
<deletedAxiom>&apos;GPI anchor release&apos; SubClassOf &apos;GPI anchor metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006511</classIRI>
<classLabel>ubiquitin-dependent protein catabolic process</classLabel>
<newAxiom>&apos;ubiquitin-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein ubiquitination&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006521</classIRI>
<classLabel>regulation of cellular amino acid metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;regulation of amine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;regulation of cellular ketone metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031507</classIRI>
<classLabel>heterochromatin formation</classLabel>
<newAxiom>&apos;heterochromatin formation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;heterochromatin boundary formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006575</classIRI>
<classLabel>cellular modified amino acid metabolic process</classLabel>
<deletedAxiom>&apos;cellular modified amino acid metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular modified amino acid metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102398</classIRI>
<classLabel>dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102399</classIRI>
<classLabel>dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity</classLabel>
<deletedAxiom>&apos;dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031552</classIRI>
<classLabel>negative regulation of brain-derived neurotrophic factor-activated receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; SubClassOf &apos;negative regulation of brain-derived neurotrophic factor receptor signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; SubClassOf &apos;negative regulation of protein tyrosine kinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; SubClassOf &apos;regulation of brain-derived neurotrophic factor-activated receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; SubClassOf &apos;negative regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;brain-derived neurotrophic factor receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of brain-derived neurotrophic factor-activated receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;brain-derived neurotrophic factor receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102385</classIRI>
<classLabel>patchoulol synthase activity</classLabel>
<deletedAxiom>&apos;patchoulol synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043539</classIRI>
<classLabel>protein serine/threonine kinase activator activity</classLabel>
<newAxiom>&apos;protein serine/threonine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102352</classIRI>
<classLabel>phosphatidate kinase activity</classLabel>
<deletedAxiom>&apos;phosphatidate kinase activity&apos; SubClassOf &apos;phosphotransferase activity, phosphate group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102356</classIRI>
<classLabel>isoitalicene synthase activity</classLabel>
<deletedAxiom>&apos;isoitalicene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031586</classIRI>
<classLabel>negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;inositol 1,4,5-trisphosphate-gated calcium channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;inositol 1,4,5-trisphosphate-gated calcium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of release of sequestered calcium ion into cytosol&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;negative regulation of calcium-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102371</classIRI>
<classLabel>betulin dehydrogenase activity</classLabel>
<deletedAxiom>&apos;betulin dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102372</classIRI>
<classLabel>alpha-amyrin 28-monooxygenase activity</classLabel>
<deletedAxiom>&apos;alpha-amyrin 28-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102370</classIRI>
<classLabel>lupeol 28-monooxygenase activity</classLabel>
<deletedAxiom>&apos;lupeol 28-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102376</classIRI>
<classLabel>lupeol 28-oxidase activity</classLabel>
<deletedAxiom>&apos;lupeol 28-oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102363</classIRI>
<classLabel>isoscopoletin-O-methyltransferase activity</classLabel>
<deletedAxiom>&apos;isoscopoletin-O-methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102368</classIRI>
<classLabel>beta-amyrin 30-monooxygenase activity</classLabel>
<deletedAxiom>&apos;beta-amyrin 30-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102301</classIRI>
<classLabel>gamma-linolenate elongase activity</classLabel>
<deletedAxiom>&apos;gamma-linolenate elongase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102330</classIRI>
<classLabel>palmitoyl-[acp] elongase/decarboxylase activity</classLabel>
<deletedAxiom>&apos;palmitoyl-[acp] elongase/decarboxylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102331</classIRI>
<classLabel>heptadecanoyl-[acp] elongase/decarboxylase activity</classLabel>
<deletedAxiom>&apos;heptadecanoyl-[acp] elongase/decarboxylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102332</classIRI>
<classLabel>fatty-acyl-[acp] elongase/decarboxylase activity</classLabel>
<deletedAxiom>&apos;fatty-acyl-[acp] elongase/decarboxylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102333</classIRI>
<classLabel>stearoyl-[acp] elongase/decarboxylase activity</classLabel>
<deletedAxiom>&apos;stearoyl-[acp] elongase/decarboxylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901710</classIRI>
<classLabel>regulation of homoserine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of homoserine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of homoserine biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901711</classIRI>
<classLabel>negative regulation of homoserine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of homoserine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901712</classIRI>
<classLabel>positive regulation of homoserine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of homoserine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901715</classIRI>
<classLabel>regulation of gamma-aminobutyric acid catabolic process</classLabel>
<deletedAxiom>&apos;regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901716</classIRI>
<classLabel>negative regulation of gamma-aminobutyric acid catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901717</classIRI>
<classLabel>positive regulation of gamma-aminobutyric acid catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of gamma-aminobutyric acid catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006412</classIRI>
<classLabel>translation</classLabel>
<newAxiom>&apos;translation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;translational termination&apos;</newAxiom>
<newAxiom>&apos;translation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;translational initiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006413</classIRI>
<classLabel>translational initiation</classLabel>
<deletedAxiom>&apos;translational initiation&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;translational initiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;formation of translation initiation ternary complex&apos;</newAxiom>
<newAxiom>&apos;translational initiation&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102272</classIRI>
<classLabel>homophytochelatin synthase activity (polymer-forming)</classLabel>
<deletedAxiom>&apos;homophytochelatin synthase activity (polymer-forming)&apos; SubClassOf &apos;aminoacyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102273</classIRI>
<classLabel>homophytochelatin synthase (dimmer forming) activity</classLabel>
<deletedAxiom>&apos;homophytochelatin synthase (dimmer forming) activity&apos; SubClassOf &apos;aminoacyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102275</classIRI>
<classLabel>cysteine-S-conjugate N-malonyl transferase activity</classLabel>
<deletedAxiom>&apos;cysteine-S-conjugate N-malonyl transferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102295</classIRI>
<classLabel>4-methylumbelliferyl glucoside 6&apos;-O-malonyltransferase activity</classLabel>
<deletedAxiom>&apos;4-methylumbelliferyl glucoside 6&apos;-O-malonyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102297</classIRI>
<classLabel>selenate adenylyltransferase activity</classLabel>
<deletedAxiom>&apos;selenate adenylyltransferase activity&apos; SubClassOf &apos;nucleotidyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102292</classIRI>
<classLabel>30-hydroxy-beta-amyrin 11-hydroxylase activity</classLabel>
<deletedAxiom>&apos;30-hydroxy-beta-amyrin 11-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102298</classIRI>
<classLabel>selenocystathione synthase activity</classLabel>
<deletedAxiom>&apos;selenocystathione synthase activity&apos; SubClassOf &apos;transferase activity, transferring alkyl or aryl (other than methyl) groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102286</classIRI>
<classLabel>ornithine N-delta-acetyltransferase activity</classLabel>
<deletedAxiom>&apos;ornithine N-delta-acetyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102281</classIRI>
<classLabel>formylaminopyrimidine deformylase activity</classLabel>
<deletedAxiom>&apos;formylaminopyrimidine deformylase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102287</classIRI>
<classLabel>4-coumaroylhexanoylmethane synthase activity</classLabel>
<deletedAxiom>&apos;4-coumaroylhexanoylmethane synthase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043450</classIRI>
<classLabel>alkene biosynthetic process</classLabel>
<deletedAxiom>&apos;alkene biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043451</classIRI>
<classLabel>alkene catabolic process</classLabel>
<deletedAxiom>&apos;alkene catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043452</classIRI>
<classLabel>cellular alkyne metabolic process</classLabel>
<deletedAxiom>&apos;cellular alkyne metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043453</classIRI>
<classLabel>alkyne biosynthetic process</classLabel>
<deletedAxiom>&apos;alkyne biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043446</classIRI>
<classLabel>cellular alkane metabolic process</classLabel>
<deletedAxiom>&apos;cellular alkane metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043447</classIRI>
<classLabel>alkane biosynthetic process</classLabel>
<deletedAxiom>&apos;alkane biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043448</classIRI>
<classLabel>alkane catabolic process</classLabel>
<deletedAxiom>&apos;alkane catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043449</classIRI>
<classLabel>cellular alkene metabolic process</classLabel>
<deletedAxiom>&apos;cellular alkene metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043467</classIRI>
<classLabel>regulation of generation of precursor metabolites and energy</classLabel>
<deletedAxiom>&apos;regulation of generation of precursor metabolites and energy&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of generation of precursor metabolites and energy&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102247</classIRI>
<classLabel>malonyl-malonyl acyl carrier protein-condensing enzyme activity</classLabel>
<deletedAxiom>&apos;malonyl-malonyl acyl carrier protein-condensing enzyme activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102248</classIRI>
<classLabel>diacylglycerol transacylase activity</classLabel>
<deletedAxiom>&apos;diacylglycerol transacylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901856</classIRI>
<classLabel>negative regulation of cellular respiration</classLabel>
<deletedAxiom>&apos;negative regulation of cellular respiration&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cellular respiration&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901857</classIRI>
<classLabel>positive regulation of cellular respiration</classLabel>
<deletedAxiom>&apos;positive regulation of cellular respiration&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of cellular respiration&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021938</classIRI>
<classLabel>smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation</classLabel>
<deletedAxiom>&apos;smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0021937</classIRI>
<classLabel>cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation</classLabel>
<deletedAxiom>&apos;cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of cerebellar granule cell precursor proliferation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102181</classIRI>
<classLabel>4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102182</classIRI>
<classLabel>4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity</classLabel>
<deletedAxiom>&apos;4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045923</classIRI>
<classLabel>positive regulation of fatty acid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of fatty acid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045922</classIRI>
<classLabel>negative regulation of fatty acid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of fatty acid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102152</classIRI>
<classLabel>Delta12-linoleate epoxygenase activity</classLabel>
<deletedAxiom>&apos;Delta12-linoleate epoxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045952</classIRI>
<classLabel>regulation of juvenile hormone catabolic process</classLabel>
<deletedAxiom>&apos;regulation of juvenile hormone catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070917</classIRI>
<classLabel>inositol phosphoceramide synthase regulator activity</classLabel>
<newAxiom>&apos;inositol phosphoceramide synthase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;inositol phosphoceramide synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102141</classIRI>
<classLabel>[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity</classLabel>
<deletedAxiom>&apos;[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity&apos; SubClassOf &apos;sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102144</classIRI>
<classLabel>carboxyspermidine dehydrogenase II activity</classLabel>
<deletedAxiom>&apos;carboxyspermidine dehydrogenase II activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102147</classIRI>
<classLabel>3&apos;-O-methyltricetin O methyl transferase activity</classLabel>
<deletedAxiom>&apos;3&apos;-O-methyltricetin O methyl transferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102173</classIRI>
<classLabel>24-methylenecycloartanol 4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;24-methylenecycloartanol 4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102174</classIRI>
<classLabel>4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045970</classIRI>
<classLabel>negative regulation of juvenile hormone catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of juvenile hormone catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045971</classIRI>
<classLabel>positive regulation of juvenile hormone catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of juvenile hormone catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031324</classIRI>
<classLabel>negative regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031323</classIRI>
<classLabel>regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular metabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031326</classIRI>
<classLabel>regulation of cellular biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of cellular biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular biosynthetic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031325</classIRI>
<classLabel>positive regulation of cellular metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular metabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular metabolic process&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031328</classIRI>
<classLabel>positive regulation of cellular biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031327</classIRI>
<classLabel>negative regulation of cellular biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular biosynthetic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular biosynthetic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102178</classIRI>
<classLabel>4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102179</classIRI>
<classLabel>24-ethylidenelophenol 4alpha-methyl oxidase activity</classLabel>
<deletedAxiom>&apos;24-ethylidenelophenol 4alpha-methyl oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031329</classIRI>
<classLabel>regulation of cellular catabolic process</classLabel>
<deletedAxiom>&apos;regulation of cellular catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular catabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cellular catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031331</classIRI>
<classLabel>positive regulation of cellular catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of cellular catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular catabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cellular catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cellular catabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031330</classIRI>
<classLabel>negative regulation of cellular catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular catabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cellular catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cellular catabolic process&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045965</classIRI>
<classLabel>negative regulation of ecdysteroid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of ecdysteroid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ecdysteroid metabolic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045966</classIRI>
<classLabel>positive regulation of ecdysteroid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of ecdysteroid metabolic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ecdysteroid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102111</classIRI>
<classLabel>gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity</classLabel>
<deletedAxiom>&apos;gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102133</classIRI>
<classLabel>limonene hydroxylase activity</classLabel>
<deletedAxiom>&apos;limonene hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102122</classIRI>
<classLabel>gibberellin A34 carboxyl methyltransferase activity</classLabel>
<deletedAxiom>&apos;gibberellin A34 carboxyl methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102123</classIRI>
<classLabel>gibberellin A4 16alpha,17 epoxidase activity</classLabel>
<deletedAxiom>&apos;gibberellin A4 16alpha,17 epoxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102124</classIRI>
<classLabel>gibberellin A12 16alpha,17 epoxidase activity</classLabel>
<deletedAxiom>&apos;gibberellin A12 16alpha,17 epoxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102125</classIRI>
<classLabel>gibberellin A9 16alpha,17 epoxidase activity</classLabel>
<deletedAxiom>&apos;gibberellin A9 16alpha,17 epoxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102119</classIRI>
<classLabel>gibberellin A20 carboxyl methyltransferase activity</classLabel>
<deletedAxiom>&apos;gibberellin A20 carboxyl methyltransferase activity&apos; SubClassOf &apos;methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045998</classIRI>
<classLabel>positive regulation of ecdysteroid biosynthetic process</classLabel>
<newAxiom>&apos;positive regulation of ecdysteroid biosynthetic process&apos; SubClassOf &apos;positive regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045997</classIRI>
<classLabel>negative regulation of ecdysteroid biosynthetic process</classLabel>
<newAxiom>&apos;negative regulation of ecdysteroid biosynthetic process&apos; SubClassOf &apos;negative regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070875</classIRI>
<classLabel>positive regulation of glycogen metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycogen metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070874</classIRI>
<classLabel>negative regulation of glycogen metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycogen metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070857</classIRI>
<classLabel>regulation of bile acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of bile acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070859</classIRI>
<classLabel>positive regulation of bile acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of bile acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070858</classIRI>
<classLabel>negative regulation of bile acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of bile acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043280</classIRI>
<classLabel>positive regulation of cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043281</classIRI>
<classLabel>regulation of cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901997</classIRI>
<classLabel>negative regulation of indoleacetic acid biosynthetic process via tryptophan</classLabel>
<newAxiom>&apos;negative regulation of indoleacetic acid biosynthetic process via tryptophan&apos; SubClassOf &apos;negative regulation of amine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102071</classIRI>
<classLabel>9,10-epoxy-18-hydroxystearate hydrolase activity</classLabel>
<deletedAxiom>&apos;9,10-epoxy-18-hydroxystearate hydrolase activity&apos; SubClassOf &apos;ether hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102063</classIRI>
<classLabel>beta-curcumene synthase activity</classLabel>
<deletedAxiom>&apos;beta-curcumene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102065</classIRI>
<classLabel>patchoulene synthase activity</classLabel>
<deletedAxiom>&apos;patchoulene synthase activity&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102066</classIRI>
<classLabel>alpha-patchoulene synthase activityy</classLabel>
<deletedAxiom>&apos;alpha-patchoulene synthase activityy&apos; SubClassOf &apos;carbon-oxygen lyase activity, acting on phosphates&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102093</classIRI>
<classLabel>acrylate:acyl-coA CoA transferase activity</classLabel>
<deletedAxiom>&apos;acrylate:acyl-coA CoA transferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102081</classIRI>
<classLabel>homotaurine:2-oxoglutarate aminotransferase activity</classLabel>
<deletedAxiom>&apos;homotaurine:2-oxoglutarate aminotransferase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102089</classIRI>
<classLabel>dehydroscoulerine synthase activity</classLabel>
<deletedAxiom>&apos;dehydroscoulerine synthase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045821</classIRI>
<classLabel>positive regulation of glycolytic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycolytic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045828</classIRI>
<classLabel>positive regulation of isoprenoid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of isoprenoid metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045827</classIRI>
<classLabel>negative regulation of isoprenoid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of isoprenoid metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045819</classIRI>
<classLabel>positive regulation of glycogen catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of glycogen catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of glycogen catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045818</classIRI>
<classLabel>negative regulation of glycogen catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of glycogen catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of glycogen catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102052</classIRI>
<classLabel>indole-3-acetyl-proline synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-proline synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102050</classIRI>
<classLabel>indole-3-acetyl-tyrosine synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-tyrosine synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102051</classIRI>
<classLabel>indole-3-acetyl-tryptophan synthetase activity</classLabel>
<deletedAxiom>&apos;indole-3-acetyl-tryptophan synthetase activity&apos; SubClassOf &apos;ligase activity, forming carbon-nitrogen bonds&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018237</classIRI>
<classLabel>urease activator activity</classLabel>
<newAxiom>&apos;urease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;urease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102004</classIRI>
<classLabel>2-octaprenyl-6-hydroxyphenol methylase activity</classLabel>
<deletedAxiom>&apos;2-octaprenyl-6-hydroxyphenol methylase activity&apos; SubClassOf &apos;2-polyprenyl-6-hydroxyphenol O-methyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018173</classIRI>
<classLabel>peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine</classLabel>
<deletedAxiom>&apos;peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031147</classIRI>
<classLabel>1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process</classLabel>
<newAxiom>&apos;1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
<newAxiom>&apos;1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;DIF dechlorinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043154</classIRI>
<classLabel>negative regulation of cysteine-type endopeptidase activity involved in apoptotic process</classLabel>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;negative regulation of apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos; SubClassOf &apos;negative regulation of cysteine-type endopeptidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055104</classIRI>
<classLabel>ligase inhibitor activity</classLabel>
<newAxiom>&apos;ligase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055103</classIRI>
<classLabel>ligase regulator activity</classLabel>
<newAxiom>&apos;ligase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055102</classIRI>
<classLabel>lipase inhibitor activity</classLabel>
<newAxiom>&apos;lipase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;lipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055106</classIRI>
<classLabel>ubiquitin-protein transferase regulator activity</classLabel>
<newAxiom>&apos;ubiquitin-protein transferase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ubiquitin-protein transferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055105</classIRI>
<classLabel>ubiquitin-protein transferase inhibitor activity</classLabel>
<newAxiom>&apos;ubiquitin-protein transferase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ubiquitin-protein transferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080142</classIRI>
<classLabel>regulation of salicylic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of salicylic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of salicylic acid biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080093</classIRI>
<classLabel>regulation of photorespiration</classLabel>
<deletedAxiom>&apos;regulation of photorespiration&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of photorespiration&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008772</classIRI>
<classLabel>[isocitrate dehydrogenase (NADP+)] kinase activity</classLabel>
<deletedAxiom>&apos;[isocitrate dehydrogenase (NADP+)] kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;[isocitrate dehydrogenase (NADP+)] kinase activity&apos; SubClassOf &apos;protein serine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045723</classIRI>
<classLabel>positive regulation of fatty acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of fatty acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045722</classIRI>
<classLabel>positive regulation of gluconeogenesis</classLabel>
<deletedAxiom>&apos;positive regulation of gluconeogenesis&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of gluconeogenesis&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045721</classIRI>
<classLabel>negative regulation of gluconeogenesis</classLabel>
<deletedAxiom>&apos;negative regulation of gluconeogenesis&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of gluconeogenesis&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045717</classIRI>
<classLabel>negative regulation of fatty acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of fatty acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045754</classIRI>
<classLabel>positive regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of acetate catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of acetate catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045753</classIRI>
<classLabel>negative regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of acetate catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of acetate catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045734</classIRI>
<classLabel>regulation of acetate catabolic process</classLabel>
<deletedAxiom>&apos;regulation of acetate catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acetate catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
<newAxiom>&apos;regulation of acetate catabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045738</classIRI>
<classLabel>negative regulation of DNA repair</classLabel>
<deletedAxiom>&apos;negative regulation of DNA repair&apos; SubClassOf &apos;negative regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045739</classIRI>
<classLabel>positive regulation of DNA repair</classLabel>
<deletedAxiom>&apos;positive regulation of DNA repair&apos; SubClassOf &apos;positive regulation of cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045763</classIRI>
<classLabel>negative regulation of cellular amino acid metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;negative regulation of amine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of cellular amino acid metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043101</classIRI>
<classLabel>purine-containing compound salvage</classLabel>
<deletedAxiom>&apos;purine-containing compound salvage&apos; SubClassOf &apos;nucleobase-containing compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045764</classIRI>
<classLabel>positive regulation of amino acid metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of amino acid metabolic process&apos; SubClassOf &apos;positive regulation of amine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of amino acid metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033782</classIRI>
<classLabel>24-hydroxycholesterol 7alpha-hydroxylase activity</classLabel>
<newAxiom>&apos;24-hydroxycholesterol 7alpha-hydroxylase activity&apos; SubClassOf &apos;oxysterol 7-alpha-hydroxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033783</classIRI>
<classLabel>25-hydroxycholesterol 7alpha-hydroxylase activity</classLabel>
<newAxiom>&apos;25-hydroxycholesterol 7alpha-hydroxylase activity&apos; SubClassOf &apos;oxysterol 7-alpha-hydroxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070624</classIRI>
<classLabel>negative regulation of thiamine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of thiamine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070623</classIRI>
<classLabel>regulation of thiamine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of thiamine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006081</classIRI>
<classLabel>cellular aldehyde metabolic process</classLabel>
<deletedAxiom>&apos;cellular aldehyde metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular aldehyde metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006082</classIRI>
<classLabel>organic acid metabolic process</classLabel>
<deletedAxiom>&apos;organic acid metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070617</classIRI>
<classLabel>negative regulation of thiamine diphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006091</classIRI>
<classLabel>generation of precursor metabolites and energy</classLabel>
<deletedAxiom>&apos;generation of precursor metabolites and energy&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;generation of precursor metabolites and energy&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070616</classIRI>
<classLabel>regulation of thiamine diphosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of thiamine diphosphate biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<newAxiom>&apos;glycolytic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006098</classIRI>
<classLabel>pentose-phosphate shunt</classLabel>
<newAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pentose-phosphate shunt, oxidative branch&apos;</newAxiom>
<newAxiom>&apos;pentose-phosphate shunt&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pentose-phosphate shunt, non-oxidative branch&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031078</classIRI>
<classLabel>histone H3K14 deacetylase activity</classLabel>
<newAxiom>&apos;histone H3K14 deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141221</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043094</classIRI>
<classLabel>cellular metabolic compound salvage</classLabel>
<deletedAxiom>&apos;cellular metabolic compound salvage&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular metabolic compound salvage&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080020</classIRI>
<classLabel>regulation of coenzyme A biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of coenzyme A biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of coenzyme A biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080069</classIRI>
<classLabel>7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080068</classIRI>
<classLabel>5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080067</classIRI>
<classLabel>4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080066</classIRI>
<classLabel>3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080071</classIRI>
<classLabel>indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0080070</classIRI>
<classLabel>8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;desulfoglucosinolate sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008603</classIRI>
<classLabel>cAMP-dependent protein kinase regulator activity</classLabel>
<newAxiom>&apos;cAMP-dependent protein kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cAMP-dependent protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008607</classIRI>
<classLabel>phosphorylase kinase regulator activity</classLabel>
<newAxiom>&apos;phosphorylase kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphorylase kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008611</classIRI>
<classLabel>ether lipid biosynthetic process</classLabel>
<deletedAxiom>&apos;ether lipid biosynthetic process&apos; SubClassOf &apos;cellular lipid biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;ether lipid biosynthetic process&apos; SubClassOf &apos;lipid biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008635</classIRI>
<classLabel>activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c</classLabel>
<deletedAxiom>&apos;activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c&apos; SubClassOf &apos;activation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008657</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity</classLabel>
<newAxiom>&apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033668</classIRI>
<classLabel>symbiont-mediated suppression of host apoptosis</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900960</classIRI>
<classLabel>negative regulation of 17-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of 17-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900961</classIRI>
<classLabel>positive regulation of 17-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of 17-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900971</classIRI>
<classLabel>regulation of sarcinapterin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900972</classIRI>
<classLabel>negative regulation of sarcinapterin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900973</classIRI>
<classLabel>positive regulation of sarcinapterin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of sarcinapterin biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900974</classIRI>
<classLabel>regulation of tatiopterin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900975</classIRI>
<classLabel>negative regulation of tatiopterin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900976</classIRI>
<classLabel>positive regulation of tatiopterin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of tatiopterin biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900947</classIRI>
<classLabel>regulation of isoprene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of isoprene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900948</classIRI>
<classLabel>negative regulation of isoprene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of isoprene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900949</classIRI>
<classLabel>positive regulation of isoprene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of isoprene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900950</classIRI>
<classLabel>regulation of 18-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of 18-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900951</classIRI>
<classLabel>negative regulation of 18-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of 18-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900952</classIRI>
<classLabel>positive regulation of 18-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of 18-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900953</classIRI>
<classLabel>regulation of 18-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;regulation of 18-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900954</classIRI>
<classLabel>negative regulation of 18-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of 18-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900955</classIRI>
<classLabel>positive regulation of 18-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of 18-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900956</classIRI>
<classLabel>regulation of 17-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of 17-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900957</classIRI>
<classLabel>negative regulation of 17-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of 17-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900958</classIRI>
<classLabel>positive regulation of 17-methylnonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of 17-methylnonadec-1-ene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900959</classIRI>
<classLabel>regulation of 17-methylnonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;regulation of 17-methylnonadec-1-ene metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008568</classIRI>
<classLabel>microtubule severing ATPase activity</classLabel>
<deletedAxiom>&apos;microtubule severing ATPase activity&apos; SubClassOf &apos;protein-containing complex destabilizing activity&apos;</deletedAxiom>
<newAxiom>&apos;microtubule severing ATPase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0170060</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900916</classIRI>
<classLabel>positive regulation of octadecene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of octadecene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900917</classIRI>
<classLabel>regulation of octadecene metabolic process</classLabel>
<deletedAxiom>&apos;regulation of octadecene metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900918</classIRI>
<classLabel>negative regulation of octadecene metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of octadecene metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900919</classIRI>
<classLabel>positive regulation of octadecene metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of octadecene metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900932</classIRI>
<classLabel>regulation of nonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;regulation of nonadec-1-ene metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900933</classIRI>
<classLabel>negative regulation of nonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of nonadec-1-ene metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900934</classIRI>
<classLabel>positive regulation of nonadec-1-ene metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of nonadec-1-ene metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900935</classIRI>
<classLabel>regulation of nonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of nonadec-1-ene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900936</classIRI>
<classLabel>negative regulation of nonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of nonadec-1-ene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900937</classIRI>
<classLabel>positive regulation of nonadec-1-ene biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of nonadec-1-ene biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008597</classIRI>
<classLabel>calcium-dependent protein serine/threonine phosphatase regulator activity</classLabel>
<newAxiom>&apos;calcium-dependent protein serine/threonine phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium-dependent protein serine/threonine phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900900</classIRI>
<classLabel>negative regulation of heptadecane metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of heptadecane metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of heptadecane metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900901</classIRI>
<classLabel>positive regulation of heptadecane metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of heptadecane metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of heptadecane metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900902</classIRI>
<classLabel>regulation of hexadecanal biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900903</classIRI>
<classLabel>negative regulation of hexadecanal biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900904</classIRI>
<classLabel>positive regulation of hexadecanal biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of hexadecanal biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900905</classIRI>
<classLabel>regulation of hexadecanal metabolic process</classLabel>
<deletedAxiom>&apos;regulation of hexadecanal metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of hexadecanal metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900906</classIRI>
<classLabel>negative regulation of hexadecanal metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of hexadecanal metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of hexadecanal metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900907</classIRI>
<classLabel>positive regulation of hexadecanal metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of hexadecanal metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of hexadecanal metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900914</classIRI>
<classLabel>regulation of octadecene biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of octadecene biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900915</classIRI>
<classLabel>negative regulation of octadecene biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of octadecene biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070452</classIRI>
<classLabel>positive regulation of ergosterol biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of ergosterol biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141208</classIRI>
<classLabel>protein lysine delactylase activity</classLabel>
<deletedAxiom>&apos;protein lysine delactylase activity&apos; SubClassOf &apos;protein lysine deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein lysine delactylase activity&apos; SubClassOf &apos;NAD-dependent protein lysine deacetylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008427</classIRI>
<classLabel>calcium-dependent protein kinase inhibitor activity</classLabel>
<newAxiom>&apos;calcium-dependent protein kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcium-dependent protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008426</classIRI>
<classLabel>protein kinase C inhibitor activity</classLabel>
<newAxiom>&apos;protein kinase C inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;diacylglycerol-dependent serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008428</classIRI>
<classLabel>ribonuclease inhibitor activity</classLabel>
<newAxiom>&apos;ribonuclease inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA nuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008396</classIRI>
<classLabel>oxysterol 7-alpha-hydroxylase activity</classLabel>
<deletedAxiom>&apos;oxysterol 7-alpha-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<deletedAxiom>&apos;oxysterol 7-alpha-hydroxylase activity&apos; SubClassOf &apos;steroid hydroxylase activity&apos;</deletedAxiom>
<newAxiom>&apos;oxysterol 7-alpha-hydroxylase activity&apos; SubClassOf &apos;steroid 7-alpha-hydroxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060961</classIRI>
<classLabel>phospholipase D inhibitor activity</classLabel>
<newAxiom>&apos;phospholipase D inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase D activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141199</classIRI>
<classLabel>GDP-mannose biosynthetic process from glucose</classLabel>
<newAxiom>&apos;GDP-mannose biosynthetic process from glucose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucose-6-phosphate isomerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070320</classIRI>
<classLabel>inward rectifier potassium channel inhibitor activity</classLabel>
<newAxiom>&apos;inward rectifier potassium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;inward rectifier potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141159</classIRI>
<classLabel>symbiont-mediated suppression of host phagosome acidification</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host phagosome acidification&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host phagosome acidification&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141158</classIRI>
<classLabel>symbiont-mediated suppression of host phagosome maturation</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host phagosome maturation&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host phagosome maturation&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141157</classIRI>
<classLabel>symbiont-mediated suppression of host exocytosis</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host exocytosis&apos; SubClassOf &apos;symbiont-mediated perturbation of host vesicle-mediated transport&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host exocytosis&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141155</classIRI>
<classLabel>symbiont-mediated suppression of host translation elongation</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host translation elongation&apos; SubClassOf &apos;symbiont-mediated suppression of host translation&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host translation elongation&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141106</classIRI>
<classLabel>tRNA methyltransferase activator activity</classLabel>
<newAxiom>&apos;tRNA methyltransferase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141104</classIRI>
<classLabel>symbiont-mediated activation of host G protein-coupled receptor signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host G protein-coupled receptor signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141109</classIRI>
<classLabel>transporter activator activity</classLabel>
<newAxiom>&apos;transporter activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141108</classIRI>
<classLabel>transporter regulator activity</classLabel>
<newAxiom>&apos;transporter regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141107</classIRI>
<classLabel>methyltransferase regulator activity</classLabel>
<newAxiom>&apos;methyltransferase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141110</classIRI>
<classLabel>transporter inhibitor activity</classLabel>
<newAxiom>&apos;transporter inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008300</classIRI>
<classLabel>isoprenoid catabolic process</classLabel>
<deletedAxiom>&apos;isoprenoid catabolic process&apos; SubClassOf &apos;cellular lipid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;isoprenoid catabolic process&apos; SubClassOf &apos;lipid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047927</classIRI>
<classLabel>gibberellin-44 dioxygenase activity</classLabel>
<deletedAxiom>&apos;gibberellin-44 dioxygenase activity&apos; SubClassOf &apos;2-oxoglutarate-dependent dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047848</classIRI>
<classLabel>dephospho-[reductase kinase] kinase activity</classLabel>
<deletedAxiom>&apos;dephospho-[reductase kinase] kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060802</classIRI>
<classLabel>epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification</classLabel>
<deletedAxiom>&apos;epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;anterior/posterior axis specification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033249</classIRI>
<classLabel>positive regulation of penicillin catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of penicillin catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of penicillin catabolic process&apos; SubClassOf &apos;positive regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033248</classIRI>
<classLabel>negative regulation of penicillin catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of penicillin catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of penicillin catabolic process&apos; SubClassOf &apos;negative regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008299</classIRI>
<classLabel>isoprenoid biosynthetic process</classLabel>
<deletedAxiom>&apos;isoprenoid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045227</classIRI>
<classLabel>capsule polysaccharide biosynthetic process</classLabel>
<deletedAxiom>&apos;capsule polysaccharide biosynthetic process&apos; SubClassOf &apos;extracellular polysaccharide biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;capsule polysaccharide biosynthetic process&apos; SubClassOf &apos;polysaccharide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045228</classIRI>
<classLabel>slime layer polysaccharide biosynthetic process</classLabel>
<deletedAxiom>&apos;slime layer polysaccharide biosynthetic process&apos; SubClassOf &apos;extracellular polysaccharide biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;slime layer polysaccharide biosynthetic process&apos; SubClassOf &apos;polysaccharide biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045226</classIRI>
<classLabel>extracellular polysaccharide biosynthetic process</classLabel>
<deletedAxiom>&apos;extracellular polysaccharide biosynthetic process&apos; SubClassOf &apos;extracellular polysaccharide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;extracellular polysaccharide biosynthetic process&apos; SubClassOf &apos;polysaccharide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033244</classIRI>
<classLabel>regulation of penicillin metabolic process</classLabel>
<newAxiom>&apos;regulation of penicillin metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033247</classIRI>
<classLabel>regulation of penicillin catabolic process</classLabel>
<deletedAxiom>&apos;regulation of penicillin catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of penicillin catabolic process&apos; SubClassOf &apos;regulation of catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141088</classIRI>
<classLabel>symbiont-mediated activation of host autophagy</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host autophagy&apos; SubClassOf &apos;induction by virus of host autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host autophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host autophagy&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated activation of host autophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141083</classIRI>
<classLabel>symbiont-mediated suppression of host reactive oxygen species generation</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host reactive oxygen species generation&apos; SubClassOf &apos;symbiont defense to host-produced reactive oxygen species&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host reactive oxygen species generation&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141081</classIRI>
<classLabel>symbiont-mediated suppression of host inflammasome-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host inflammasome-mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;inflammasome-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host inflammasome-mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;inflammasome-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host inflammasome-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host inflammasome-mediated signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141080</classIRI>
<classLabel>symbiont-mediated activation of host interferon signaling pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host interferon signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;interferon-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host interferon signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;interferon-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141074</classIRI>
<classLabel>symbiont-mediated suppression of host cGAS-STING signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host cGAS-STING signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host cGAS-STING signal transduction&apos; SubClassOf &apos;symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141073</classIRI>
<classLabel>symbiont-mediated perturbation of host opsonization</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host opsonization&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host opsonization&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141079</classIRI>
<classLabel>symbiont-mediated activation of host inflammasome-mediated signal transduction</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host inflammasome-mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;inflammasome-mediated signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host inflammasome-mediated signal transduction&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;inflammasome-mediated signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141071</classIRI>
<classLabel>symbiont-mediated activation of host MAPK cascade</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;MAPK cascade&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host MAPK cascade&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;MAPK cascade&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141070</classIRI>
<classLabel>symbiont-mediated suppression of host MAPK cascade</classLabel>
<newAxiom>&apos;symbiont-mediated suppression of host MAPK cascade&apos; SubClassOf &apos;symbiont-mediated suppression of host signal transduction pathway&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141069</classIRI>
<classLabel>receptor ligand inhibitor activity</classLabel>
<newAxiom>&apos;receptor ligand inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;receptor ligand activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141029</classIRI>
<classLabel>symbiont-mediated disruption of host focal adhesion</classLabel>
<deletedAxiom>&apos;symbiont-mediated disruption of host focal adhesion&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated disruption of host focal adhesion&apos; SubClassOf &apos;symbiont-mediated disruption of host cellular anatomical entity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141023</classIRI>
<classLabel>symbiont-mediated disruption of host cell-cell adhesion</classLabel>
<deletedAxiom>&apos;symbiont-mediated disruption of host cell-cell adhesion&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cell-cell adhesion&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated disruption of host cell-cell adhesion&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cell-cell adhesion&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated disruption of host cell-cell adhesion&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated disruption of host cell-cell adhesion&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141005</classIRI>
<classLabel>retrotransposon silencing by heterochromatin formation</classLabel>
<deletedAxiom>&apos;retrotransposon silencing by heterochromatin formation&apos; SubClassOf &apos;heterochromatin formation&apos;</deletedAxiom>
<newAxiom>&apos;retrotransposon silencing by heterochromatin formation&apos; SubClassOf &apos;constitutive heterochromatin formation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035800</classIRI>
<classLabel>deubiquitinase activator activity</classLabel>
<newAxiom>&apos;deubiquitinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;deubiquitinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008200</classIRI>
<classLabel>ion channel inhibitor activity</classLabel>
<newAxiom>&apos;ion channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;monoatomic ion channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008204</classIRI>
<classLabel>ergosterol metabolic process</classLabel>
<deletedAxiom>&apos;ergosterol metabolic process&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008207</classIRI>
<classLabel>C21-steroid hormone metabolic process</classLabel>
<deletedAxiom>&apos;C21-steroid hormone metabolic process&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008212</classIRI>
<classLabel>mineralocorticoid metabolic process</classLabel>
<deletedAxiom>&apos;mineralocorticoid metabolic process&apos; SubClassOf &apos;cellular process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008218</classIRI>
<classLabel>bioluminescence</classLabel>
<deletedAxiom>&apos;bioluminescence&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;bioluminescence&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060703</classIRI>
<classLabel>deoxyribonuclease inhibitor activity</classLabel>
<newAxiom>&apos;deoxyribonuclease inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA nuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008152</classIRI>
<classLabel>metabolic process</classLabel>
<deletedAxiom>&apos;metabolic process&apos; SubClassOf &apos;biological_process&apos;</deletedAxiom>
<newAxiom>&apos;metabolic process&apos; SubClassOf &apos;cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008160</classIRI>
<classLabel>protein tyrosine phosphatase activator activity</classLabel>
<newAxiom>&apos;protein tyrosine phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein tyrosine phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008191</classIRI>
<classLabel>metalloendopeptidase inhibitor activity</classLabel>
<newAxiom>&apos;metalloendopeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;metalloendopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045129</classIRI>
<classLabel>NAD-independent histone deacetylase activity</classLabel>
<deletedAxiom>&apos;NAD-independent histone deacetylase activity&apos; SubClassOf &apos;histone deacetylase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045122</classIRI>
<classLabel>aflatoxin biosynthetic process</classLabel>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fatty-acyl-CoA synthase activity&apos;</newAxiom>
<newAxiom>&apos;aflatoxin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;aflatoxin B synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060732</classIRI>
<classLabel>positive regulation of inositol phosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of inositol phosphate biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045181</classIRI>
<classLabel>glutamate synthase activity, NAD(P)H as acceptor</classLabel>
<deletedAxiom>&apos;glutamate synthase activity, NAD(P)H as acceptor&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;glutamate synthase activity, NAD(P)H as acceptor&apos; SubClassOf &apos;glutamate synthase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008123</classIRI>
<classLabel>cholesterol 7-alpha-monooxygenase activity</classLabel>
<deletedAxiom>&apos;cholesterol 7-alpha-monooxygenase activity&apos; SubClassOf &apos;steroid hydroxylase activity&apos;</deletedAxiom>
<newAxiom>&apos;cholesterol 7-alpha-monooxygenase activity&apos; SubClassOf &apos;steroid 7-alpha-hydroxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008047</classIRI>
<classLabel>enzyme activator activity</classLabel>
<newAxiom>&apos;enzyme activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045017</classIRI>
<classLabel>glycerolipid biosynthetic process</classLabel>
<deletedAxiom>&apos;glycerolipid biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008073</classIRI>
<classLabel>ornithine decarboxylase inhibitor activity</classLabel>
<newAxiom>&apos;ornithine decarboxylase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ornithine decarboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060696</classIRI>
<classLabel>regulation of phospholipid catabolic process</classLabel>
<deletedAxiom>&apos;regulation of phospholipid catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060697</classIRI>
<classLabel>positive regulation of phospholipid catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of phospholipid catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060698</classIRI>
<classLabel>endoribonuclease inhibitor activity</classLabel>
<newAxiom>&apos;endoribonuclease inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072587</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity</classLabel>
<newAxiom>&apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072586</classIRI>
<classLabel>DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity</classLabel>
<newAxiom>&apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072592</classIRI>
<classLabel>oxygen metabolic process</classLabel>
<deletedAxiom>&apos;oxygen metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;oxygen metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072593</classIRI>
<classLabel>reactive oxygen species metabolic process</classLabel>
<deletedAxiom>&apos;reactive oxygen species metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;reactive oxygen species metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047500</classIRI>
<classLabel>(+)-borneol dehydrogenase activity</classLabel>
<newAxiom>&apos;(+)-borneol dehydrogenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;(+)-camphor biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060556</classIRI>
<classLabel>regulation of vitamin D biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of vitamin D biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060557</classIRI>
<classLabel>positive regulation of vitamin D biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of vitamin D biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106394</classIRI>
<classLabel>negative regulation of palmitic acid catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of palmitic acid catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106393</classIRI>
<classLabel>regulation of palmitic acid catabolic process</classLabel>
<deletedAxiom>&apos;regulation of palmitic acid catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106395</classIRI>
<classLabel>positive regulation of palmitic acid catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of palmitic acid catabolic process&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060590</classIRI>
<classLabel>ATPase regulator activity</classLabel>
<newAxiom>&apos;ATPase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ATP-dependent activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060589</classIRI>
<classLabel>nucleoside-triphosphatase regulator activity</classLabel>
<newAxiom>&apos;nucleoside-triphosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ribonucleoside triphosphate phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072542</classIRI>
<classLabel>protein phosphatase activator activity</classLabel>
<newAxiom>&apos;protein phosphatase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106340</classIRI>
<classLabel>tRNA (cytidine(32)/guanosine(34)-2&apos;-O)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;tRNA (cytidine(32)/guanosine(34)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;tRNA (cytidine(32)/guanosine(34)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (cytidine) methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA (cytidine(32)/guanosine(34)-2&apos;-O)-methyltransferase activity&apos; SubClassOf &apos;tRNA (guanine) methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060422</classIRI>
<classLabel>peptidyl-dipeptidase inhibitor activity</classLabel>
<newAxiom>&apos;peptidyl-dipeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;peptidyl-dipeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106231</classIRI>
<classLabel>protein-propionyllysine depropionylase activity</classLabel>
<deletedAxiom>&apos;protein-propionyllysine depropionylase activity&apos; SubClassOf &apos;protein lysine deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;protein-propionyllysine depropionylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141218</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098989</classIRI>
<classLabel>NMDA selective glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;NMDA selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;NMDA glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098990</classIRI>
<classLabel>AMPA selective glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;AMPA selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;AMPA glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098991</classIRI>
<classLabel>kainate selective glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;kainate selective glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;kainate selective glutamate receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060308</classIRI>
<classLabel>GTP cyclohydrolase I regulator activity</classLabel>
<newAxiom>&apos;GTP cyclohydrolase I regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;GTP cyclohydrolase I activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072316</classIRI>
<classLabel>alpha-glucan catabolic process involved in ascospore release from ascus</classLabel>
<deletedAxiom>&apos;alpha-glucan catabolic process involved in ascospore release from ascus&apos; SubClassOf &apos;extracellular polysaccharide catabolic process involved in ascospore release from ascus&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-glucan catabolic process involved in ascospore release from ascus&apos; SubClassOf &apos;alpha-glucan catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;alpha-glucan catabolic process involved in ascospore release from ascus&apos; EquivalentTo &apos;alpha-glucan catabolic process&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ascospore release from ascus&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106112</classIRI>
<classLabel>negative regulation of mitotic cohesin ssDNA (lagging strand) loading</classLabel>
<deletedAxiom>&apos;negative regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;negative regulation of mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin ssDNA (lagging strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106111</classIRI>
<classLabel>regulation of mitotic cohesin ssDNA (lagging strand) loading</classLabel>
<deletedAxiom>&apos;regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106114</classIRI>
<classLabel>regulation of mitotic cohesin dsDNA (leading strand) loading</classLabel>
<deletedAxiom>&apos;regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin dsDNA (leading strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106113</classIRI>
<classLabel>positive regulation of mitotic cohesin ssDNA (lagging strand) loading</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin ssDNA (lagging strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin ssDNA (lagging strand) loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;positive regulation of mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106116</classIRI>
<classLabel>positive regulation of mitotic cohesin dsDNA (leading strand) loading</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin dsDNA (leading strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;positive regulation of mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin dsDNA (leading strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106115</classIRI>
<classLabel>negative regulation of mitotic cohesin dsDNA (leading strand) loading</classLabel>
<deletedAxiom>&apos;negative regulation of mitotic cohesin dsDNA (leading strand) loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;regulation of mitotic cohesin dsDNA (leading strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin dsDNA (leading strand) loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;negative regulation of mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060271</classIRI>
<classLabel>cilium assembly</classLabel>
<newAxiom>&apos;cilium assembly&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;ciliary basal body-plasma membrane docking&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106109</classIRI>
<classLabel>positive regulation of (R)-mevalonic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106108</classIRI>
<classLabel>negative regulation of (R)-mevalonic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106107</classIRI>
<classLabel>regulation of (R)-mevalonic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of (R)-mevalonic acid biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098876</classIRI>
<classLabel>vesicle-mediated transport to the plasma membrane</classLabel>
<newAxiom>&apos;vesicle-mediated transport to the plasma membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;exocytosis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905038</classIRI>
<classLabel>regulation of membrane lipid metabolic process</classLabel>
<deletedAxiom>&apos;regulation of membrane lipid metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035209</classIRI>
<classLabel>pupal development</classLabel>
<newAxiom>&apos;pupal development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;apolysis&apos;</newAxiom>
<newAxiom>&apos;pupal development&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;eclosion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905085</classIRI>
<classLabel>regulation of bioluminescence</classLabel>
<deletedAxiom>&apos;regulation of bioluminescence&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of bioluminescence&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905086</classIRI>
<classLabel>negative regulation of bioluminescence</classLabel>
<deletedAxiom>&apos;negative regulation of bioluminescence&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of bioluminescence&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050812</classIRI>
<classLabel>regulation of acyl-CoA biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of acyl-CoA biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of acyl-CoA biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905087</classIRI>
<classLabel>positive regulation of bioluminescence</classLabel>
<deletedAxiom>&apos;positive regulation of bioluminescence&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of bioluminescence&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035235</classIRI>
<classLabel>ionotropic glutamate receptor signaling pathway</classLabel>
<newAxiom>&apos;ionotropic glutamate receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glutamate-gated receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060230</classIRI>
<classLabel>lipoprotein lipase activator activity</classLabel>
<newAxiom>&apos;lipoprotein lipase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;lipoprotein lipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060228</classIRI>
<classLabel>phosphatidylcholine-sterol O-acyltransferase activator activity</classLabel>
<newAxiom>&apos;phosphatidylcholine-sterol O-acyltransferase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phosphatidylcholine-sterol O-acyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060229</classIRI>
<classLabel>lipase activator activity</classLabel>
<newAxiom>&apos;lipase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;lipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060241</classIRI>
<classLabel>lysozyme inhibitor activity</classLabel>
<newAxiom>&apos;lysozyme inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;lysozyme activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047275</classIRI>
<classLabel>glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity</classLabel>
<deletedAxiom>&apos;glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity&apos; SubClassOf &apos;UDP-galactosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060141</classIRI>
<classLabel>positive regulation of syncytium formation by virus</classLabel>
<deletedAxiom>&apos;positive regulation of syncytium formation by virus&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of syncytium formation by virus&apos; SubClassOf &apos;modulation by virus of syncytium formation via plasma membrane fusion&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of syncytium formation by virus&apos; SubClassOf &apos;positive regulation of syncytium formation by plasma membrane fusion&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of syncytium formation by virus&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060140</classIRI>
<classLabel>modulation by virus of syncytium formation via plasma membrane fusion</classLabel>
<deletedAxiom>&apos;modulation by virus of syncytium formation via plasma membrane fusion&apos; SubClassOf &apos;regulation of syncytium formation by plasma membrane fusion&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of syncytium formation via plasma membrane fusion&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;induction by virus of host cell-cell fusion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098744</classIRI>
<classLabel>1-phosphatidylinositol 4-kinase activator activity</classLabel>
<newAxiom>&apos;1-phosphatidylinositol 4-kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;1-phosphatidylinositol 4-kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905013</classIRI>
<classLabel>negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan</classLabel>
<newAxiom>&apos;negative regulation of &apos;de novo&apos; NAD biosynthetic process from tryptophan&apos; SubClassOf &apos;negative regulation of amine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001887</classIRI>
<classLabel>selenium compound metabolic process</classLabel>
<deletedAxiom>&apos;selenium compound metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;selenium compound metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905156</classIRI>
<classLabel>negative regulation of photosynthesis</classLabel>
<deletedAxiom>&apos;negative regulation of photosynthesis&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of photosynthesis&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905157</classIRI>
<classLabel>positive regulation of photosynthesis</classLabel>
<deletedAxiom>&apos;positive regulation of photosynthesis&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of photosynthesis&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050746</classIRI>
<classLabel>regulation of lipoprotein metabolic process</classLabel>
<deletedAxiom>&apos;regulation of lipoprotein metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050747</classIRI>
<classLabel>positive regulation of lipoprotein metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of lipoprotein metabolic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of lipoprotein metabolic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050748</classIRI>
<classLabel>negative regulation of lipoprotein metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of lipoprotein metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098664</classIRI>
<classLabel>G protein-coupled serotonin receptor signaling pathway</classLabel>
<newAxiom>&apos;G protein-coupled serotonin receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;G protein-coupled serotonin receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098673</classIRI>
<classLabel>inhibition of host DNA replication by virus</classLabel>
<deletedAxiom>&apos;inhibition of host DNA replication by virus&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<newAxiom>&apos;inhibition of host DNA replication by virus&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0072000</classIRI>
<classLabel>extracellular polysaccharide catabolic process involved in ascospore release from ascus</classLabel>
<deletedAxiom>&apos;extracellular polysaccharide catabolic process involved in ascospore release from ascus&apos; EquivalentTo &apos;extracellular polysaccharide catabolic process&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ascospore release from ascus&apos;)</deletedAxiom>
<deletedAxiom>&apos;extracellular polysaccharide catabolic process involved in ascospore release from ascus&apos; SubClassOf &apos;extracellular polysaccharide catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;extracellular polysaccharide catabolic process involved in ascospore release from ascus&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;ascospore release from ascus&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098676</classIRI>
<classLabel>modulation of host virulence by virus</classLabel>
<deletedAxiom>&apos;modulation of host virulence by virus&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
<newAxiom>&apos;modulation of host virulence by virus&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050665</classIRI>
<classLabel>hydrogen peroxide biosynthetic process</classLabel>
<deletedAxiom>&apos;hydrogen peroxide biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047012</classIRI>
<classLabel>sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity</classLabel>
<deletedAxiom>&apos;sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035033</classIRI>
<classLabel>histone deacetylase regulator activity</classLabel>
<newAxiom>&apos;histone deacetylase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone deacetylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035034</classIRI>
<classLabel>histone acetyltransferase regulator activity</classLabel>
<newAxiom>&apos;histone acetyltransferase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;histone acetyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001671</classIRI>
<classLabel>ATPase activator activity</classLabel>
<newAxiom>&apos;ATPase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ATP-dependent activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905309</classIRI>
<classLabel>positive regulation of cohesin loading</classLabel>
<deletedAxiom>&apos;positive regulation of cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin loading&apos; SubClassOf &apos;positive regulation of cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin loading&apos; SubClassOf &apos;positive regulation of protein localization to chromatin&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cohesin loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin loading&apos; SubClassOf &apos;regulation of cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905339</classIRI>
<classLabel>positive regulation of cohesin unloading</classLabel>
<deletedAxiom>&apos;positive regulation of cohesin unloading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cohesin unloading&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin unloading&apos; SubClassOf &apos;positive regulation of biological process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cohesin unloading&apos; SubClassOf &apos;regulation of cohesin unloading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905338</classIRI>
<classLabel>negative regulation of cohesin unloading</classLabel>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cohesin unloading&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;regulation of cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;positive regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;positive regulation of sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin unloading&apos; SubClassOf &apos;negative regulation of biological process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905343</classIRI>
<classLabel>regulation of cohesin unloading</classLabel>
<deletedAxiom>&apos;regulation of cohesin unloading&apos; SubClassOf &apos;regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin unloading&apos; SubClassOf &apos;regulation of sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin unloading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cohesin unloading&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050359</classIRI>
<classLabel>tropomyosin kinase activity</classLabel>
<deletedAxiom>&apos;tropomyosin kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050321</classIRI>
<classLabel>tau-protein kinase activity</classLabel>
<deletedAxiom>&apos;tau-protein kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;tau-protein kinase activity&apos; SubClassOf &apos;protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905412</classIRI>
<classLabel>negative regulation of mitotic cohesin loading</classLabel>
<deletedAxiom>&apos;negative regulation of mitotic cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin loading&apos; SubClassOf &apos;negative regulation of cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin loading&apos; SubClassOf &apos;regulation of mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of mitotic cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;mitotic cohesin loading&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905410</classIRI>
<classLabel>regulation of mitotic cohesin unloading</classLabel>
<deletedAxiom>&apos;regulation of mitotic cohesin unloading&apos; SubClassOf &apos;regulation of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin unloading&apos; SubClassOf &apos;regulation of cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin unloading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin unloading&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905411</classIRI>
<classLabel>positive regulation of mitotic cohesin unloading</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic cohesin unloading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin unloading&apos; SubClassOf &apos;regulation of mitotic cohesin unloading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin unloading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin unloading&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin unloading&apos; SubClassOf &apos;positive regulation of cohesin unloading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050369</classIRI>
<classLabel>[tyrosine 3-monooxygenase] kinase activity</classLabel>
<deletedAxiom>&apos;[tyrosine 3-monooxygenase] kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;[tyrosine 3-monooxygenase] kinase activity&apos; SubClassOf &apos;protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905405</classIRI>
<classLabel>regulation of mitotic cohesin loading</classLabel>
<deletedAxiom>&apos;regulation of mitotic cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin loading&apos; SubClassOf &apos;regulation of cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of mitotic cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;mitotic cohesin loading&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905406</classIRI>
<classLabel>positive regulation of mitotic cohesin loading</classLabel>
<deletedAxiom>&apos;positive regulation of mitotic cohesin loading&apos; SubClassOf &apos;regulation of mitotic cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin loading&apos; SubClassOf &apos;positive regulation of cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mitotic cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905448</classIRI>
<classLabel>positive regulation of mitochondrial ATP synthesis coupled electron transport</classLabel>
<deletedAxiom>&apos;positive regulation of mitochondrial ATP synthesis coupled electron transport&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of mitochondrial ATP synthesis coupled electron transport&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015979</classIRI>
<classLabel>photosynthesis</classLabel>
<deletedAxiom>&apos;photosynthesis&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;photosynthesis&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050108</classIRI>
<classLabel>obsolete monoterpenyl-diphosphatase activity</classLabel>
<newAxiom>&apos;obsolete monoterpenyl-diphosphatase activity&apos; SubClassOf &apos;phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062133</classIRI>
<classLabel>negative regulation of L-glutamine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of L-glutamine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062132</classIRI>
<classLabel>regulation of L-glutamine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of L-glutamine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062134</classIRI>
<classLabel>positive regulation of L-glutamine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of L-glutamine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905694</classIRI>
<classLabel>negative regulation of phosphatidic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905695</classIRI>
<classLabel>positive regulation of phosphatidic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905693</classIRI>
<classLabel>regulation of phosphatidic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phosphatidic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039722</classIRI>
<classLabel>symbiont-mediated suppression of host toll-like receptor signaling pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host toll-like receptor signaling pathway&apos; SubClassOf &apos;symbiont-mediated suppression of host innate immune response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039672</classIRI>
<classLabel>suppression by virus of host natural killer cell activation</classLabel>
<deletedAxiom>&apos;suppression by virus of host natural killer cell activation&apos; SubClassOf &apos;negative regulation of natural killer cell activation&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052635</classIRI>
<classLabel>C-20 gibberellin 2-beta-dioxygenase activity</classLabel>
<deletedAxiom>&apos;C-20 gibberellin 2-beta-dioxygenase activity&apos; SubClassOf &apos;gibberellin 2-beta-dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052634</classIRI>
<classLabel>C-19 gibberellin 2-beta-dioxygenase activity</classLabel>
<deletedAxiom>&apos;C-19 gibberellin 2-beta-dioxygenase activity&apos; SubClassOf &apos;gibberellin 2-beta-dioxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062022</classIRI>
<classLabel>mitotic cohesin ssDNA (lagging strand) loading</classLabel>
<deletedAxiom>&apos;mitotic cohesin ssDNA (lagging strand) loading&apos; SubClassOf &apos;mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062021</classIRI>
<classLabel>mitotic cohesin dsDNA (leading strand) loading</classLabel>
<deletedAxiom>&apos;mitotic cohesin dsDNA (leading strand) loading&apos; SubClassOf &apos;mitotic cohesin loading&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052677</classIRI>
<classLabel>D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity</classLabel>
<deletedAxiom>&apos;D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062090</classIRI>
<classLabel>positive regulation of taurine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of taurine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of taurine biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062097</classIRI>
<classLabel>chemosynthesis</classLabel>
<deletedAxiom>&apos;chemosynthesis&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;chemosynthesis&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062089</classIRI>
<classLabel>regulation of taurine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of taurine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of taurine biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990505</classIRI>
<classLabel>mitotic DNA replication maintenance of fidelity</classLabel>
<newAxiom>&apos;mitotic DNA replication maintenance of fidelity&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039606</classIRI>
<classLabel>symbiont-mediated suppression of host translation initiation</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host translation initiation&apos; SubClassOf &apos;symbiont-mediated suppression of host translation&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host translation initiation&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039602</classIRI>
<classLabel>symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter&apos; SubClassOf &apos;symbiont-mediated suppression of host transcription&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host transcription initiation from RNA polymerase II promoter&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039604</classIRI>
<classLabel>symbiont-mediated suppression of host translation</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host translation&apos; SubClassOf &apos;symbiont-mediated perturbation of host translation&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host translation&apos; SubClassOf &apos;symbiont-mediated suppression of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host translation&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904605</classIRI>
<classLabel>positive regulation of advanced glycation end-product receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of advanced glycation end-product receptor activity&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of advanced glycation end-product receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;advanced glycation end-product receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of advanced glycation end-product receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;advanced glycation end-product receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of advanced glycation end-product receptor activity&apos; SubClassOf &apos;regulation of advanced glycation end-product receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990583</classIRI>
<classLabel>phospholipase D activator activity</classLabel>
<newAxiom>&apos;phospholipase D activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;phospholipase D activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039657</classIRI>
<classLabel>symbiont-mediated suppression of host gene expression</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host gene expression&apos; SubClassOf &apos;symbiont-mediated perturbation of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host gene expression&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039653</classIRI>
<classLabel>symbiont-mediated suppression of host transcription</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host transcription&apos; SubClassOf &apos;symbiont-mediated suppression of host gene expression&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host transcription&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039646</classIRI>
<classLabel>symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint&apos; SubClassOf &apos;symbiont-mediated perturbation of host cell cycle progression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host cell cycle G0/G1 transition checkpoint&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904514</classIRI>
<classLabel>positive regulation of initiation of premeiotic DNA replication</classLabel>
<newAxiom>&apos;positive regulation of initiation of premeiotic DNA replication&apos; SubClassOf &apos;positive regulation of reproductive process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039595</classIRI>
<classLabel>symbiont-mediated degradation of host mRNA</classLabel>
<deletedAxiom>&apos;symbiont-mediated degradation of host mRNA&apos; SubClassOf &apos;symbiont-mediated suppression of host translation&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated degradation of host mRNA&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;mRNA catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated degradation of host mRNA&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039592</classIRI>
<classLabel>symbiont-mediated arrest of host cell cycle during G2/M transition</classLabel>
<deletedAxiom>&apos;symbiont-mediated arrest of host cell cycle during G2/M transition&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated arrest of host cell cycle during G2/M transition&apos; SubClassOf &apos;symbiont-mediated perturbation of host cell cycle progression&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated arrest of host cell cycle during G2/M transition&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;G2/M transition of mitotic cell cycle&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated arrest of host cell cycle during G2/M transition&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052553</classIRI>
<classLabel>symbiont-mediated perturbation of host immune response</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated perturbation of host immune response&apos; SubClassOf &apos;response to host immune response&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052562</classIRI>
<classLabel>symbiont-mediated suppression of host immune response</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990610</classIRI>
<classLabel>acetolactate synthase regulator activity</classLabel>
<newAxiom>&apos;acetolactate synthase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;acetolactate synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904727</classIRI>
<classLabel>negative regulation of replicative senescence</classLabel>
<deletedAxiom>&apos;negative regulation of replicative senescence&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of replicative senescence&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904728</classIRI>
<classLabel>positive regulation of replicative senescence</classLabel>
<deletedAxiom>&apos;positive regulation of replicative senescence&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of replicative senescence&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904726</classIRI>
<classLabel>regulation of replicative senescence</classLabel>
<deletedAxiom>&apos;regulation of replicative senescence&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of replicative senescence&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039525</classIRI>
<classLabel>modulation by virus of host chromatin organization</classLabel>
<deletedAxiom>&apos;modulation by virus of host chromatin organization&apos; EquivalentTo &apos;modulation by virus of host process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin organization&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf &apos;modulation by virus of host process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chromatin organization&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host chromatin organization&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039522</classIRI>
<classLabel>symbiont-mediated suppression of host mRNA export from nucleus</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host mRNA export from nucleus&apos; SubClassOf &apos;symbiont-mediated suppression of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host mRNA export from nucleus&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0039524</classIRI>
<classLabel>symbiont-mediated suppression of host mRNA processing</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host mRNA processing&apos; SubClassOf &apos;symbiont-mediated suppression of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host mRNA processing&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902005</classIRI>
<classLabel>regulation of proline biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of proline biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902006</classIRI>
<classLabel>negative regulation of proline biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of proline biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990609</classIRI>
<classLabel>glutamate-cysteine ligase regulator activity</classLabel>
<newAxiom>&apos;glutamate-cysteine ligase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;glutamate-cysteine ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990600</classIRI>
<classLabel>single-stranded DNA endodeoxyribonuclease activator activity</classLabel>
<newAxiom>&apos;single-stranded DNA endodeoxyribonuclease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;single-stranded DNA endodeoxyribonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902090</classIRI>
<classLabel>regulation of fumagillin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902092</classIRI>
<classLabel>positive regulation of fumagillin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902091</classIRI>
<classLabel>negative regulation of fumagillin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of fumagillin biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990749</classIRI>
<classLabel>polynucleotide adenylyltransferase activator activity</classLabel>
<newAxiom>&apos;polynucleotide adenylyltransferase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;poly(A) RNA polymerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904826</classIRI>
<classLabel>regulation of hydrogen sulfide biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904827</classIRI>
<classLabel>negative regulation of hydrogen sulfide biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904828</classIRI>
<classLabel>positive regulation of hydrogen sulfide biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of hydrogen sulfide biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015459</classIRI>
<classLabel>potassium channel regulator activity</classLabel>
<newAxiom>&apos;potassium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904774</classIRI>
<classLabel>negative regulation of ubiquinone biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of ubiquinone biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of ubiquinone biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904775</classIRI>
<classLabel>positive regulation of ubiquinone biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of ubiquinone biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ubiquinone biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030995</classIRI>
<classLabel>cell septum edging catabolic process</classLabel>
<deletedAxiom>&apos;cell septum edging catabolic process&apos; SubClassOf &apos;extracellular polysaccharide catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cell septum edging catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cell septum edging catabolic process&apos; SubClassOf &apos;polysaccharide catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042979</classIRI>
<classLabel>ornithine decarboxylase regulator activity</classLabel>
<newAxiom>&apos;ornithine decarboxylase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ornithine decarboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042978</classIRI>
<classLabel>ornithine decarboxylase activator activity</classLabel>
<newAxiom>&apos;ornithine decarboxylase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ornithine decarboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052323</classIRI>
<classLabel>negative regulation of phytoalexin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phytoalexin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052322</classIRI>
<classLabel>positive regulation of phytoalexin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phytoalexin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052318</classIRI>
<classLabel>regulation of phytoalexin metabolic process</classLabel>
<deletedAxiom>&apos;regulation of phytoalexin metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052319</classIRI>
<classLabel>regulation of phytoalexin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phytoalexin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052321</classIRI>
<classLabel>negative regulation of phytoalexin metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of phytoalexin metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of phytoalexin metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052320</classIRI>
<classLabel>positive regulation of phytoalexin metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of phytoalexin metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of phytoalexin metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902160</classIRI>
<classLabel>negative regulation of cyclic nucleotide-gated ion channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;regulation of cyclic nucleotide-gated ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cyclic nucleotide-activated monoatomic ion channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cyclic nucleotide-gated ion channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cyclic nucleotide-activated monoatomic ion channel activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001196</classIRI>
<classLabel>positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine</classLabel>
<deletedAxiom>&apos;positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904965</classIRI>
<classLabel>regulation of vitamin E biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of vitamin E biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of vitamin E biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904966</classIRI>
<classLabel>positive regulation of vitamin E biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of vitamin E biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of vitamin E biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904963</classIRI>
<classLabel>regulation of phytol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phytol biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904964</classIRI>
<classLabel>positive regulation of phytol biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phytol biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001172</classIRI>
<classLabel>positive regulation of glycolytic fermentation to ethanol</classLabel>
<deletedAxiom>&apos;positive regulation of glycolytic fermentation to ethanol&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001158</classIRI>
<classLabel>positive regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;positive regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001157</classIRI>
<classLabel>negative regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;negative regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001156</classIRI>
<classLabel>regulation of proline catabolic process to glutamate</classLabel>
<deletedAxiom>&apos;regulation of proline catabolic process to glutamate&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902224</classIRI>
<classLabel>ketone body metabolic process</classLabel>
<newAxiom>&apos;ketone body metabolic process&apos; SubClassOf &apos;small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904876</classIRI>
<classLabel>negative regulation of DNA ligase activity</classLabel>
<deletedAxiom>&apos;negative regulation of DNA ligase activity&apos; SubClassOf &apos;negative regulation of ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA ligase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA ligase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA ligase activity&apos; SubClassOf &apos;negative regulation of DNA ligation&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA ligase activity&apos; SubClassOf &apos;regulation of DNA ligase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of DNA ligase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA ligase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003317</classIRI>
<classLabel>cardioblast cell midline fusion</classLabel>
<newAxiom>&apos;cardioblast cell midline fusion&apos; SubClassOf &apos;cell adhesion involved in heart morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003314</classIRI>
<classLabel>heart rudiment morphogenesis</classLabel>
<newAxiom>&apos;heart rudiment morphogenesis&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;heart morphogenesis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052201</classIRI>
<classLabel>response to symbiont defenses</classLabel>
<deletedAxiom>&apos;response to symbiont defenses&apos; SubClassOf &apos;response to defenses of other organism&apos;</deletedAxiom>
<deletedAxiom>&apos;response to symbiont defenses&apos; SubClassOf &apos;response to symbiont&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990846</classIRI>
<classLabel>ribonucleoside-diphosphate reductase inhibitor activity</classLabel>
<newAxiom>&apos;ribonucleoside-diphosphate reductase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ribonucleoside-diphosphate reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902292</classIRI>
<classLabel>cell cycle DNA replication initiation</classLabel>
<newAxiom>&apos;cell cycle DNA replication initiation&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902291</classIRI>
<classLabel>cell cycle DNA replication DNA ligation</classLabel>
<newAxiom>&apos;cell cycle DNA replication DNA ligation&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902294</classIRI>
<classLabel>cell cycle DNA replication termination</classLabel>
<newAxiom>&apos;cell cycle DNA replication termination&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902296</classIRI>
<classLabel>DNA strand elongation involved in cell cycle DNA replication</classLabel>
<newAxiom>&apos;DNA strand elongation involved in cell cycle DNA replication&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902298</classIRI>
<classLabel>cell cycle DNA replication maintenance of fidelity</classLabel>
<newAxiom>&apos;cell cycle DNA replication maintenance of fidelity&apos; SubClassOf &apos;cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042811</classIRI>
<classLabel>pheromone biosynthetic process</classLabel>
<deletedAxiom>&apos;pheromone biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042810</classIRI>
<classLabel>pheromone metabolic process</classLabel>
<deletedAxiom>&apos;pheromone metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001029</classIRI>
<classLabel>regulation of cellular glucuronidation</classLabel>
<newAxiom>&apos;regulation of cellular glucuronidation&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001031</classIRI>
<classLabel>positive regulation of cellular glucuronidation</classLabel>
<deletedAxiom>&apos;positive regulation of cellular glucuronidation&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001030</classIRI>
<classLabel>negative regulation of cellular glucuronidation</classLabel>
<deletedAxiom>&apos;negative regulation of cellular glucuronidation&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904984</classIRI>
<classLabel>regulation of quinolinate biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904985</classIRI>
<classLabel>negative regulation of quinolinate biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904986</classIRI>
<classLabel>positive regulation of quinolinate biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of quinolinate biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042762</classIRI>
<classLabel>regulation of sulfur metabolic process</classLabel>
<deletedAxiom>&apos;regulation of sulfur metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of sulfur metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042744</classIRI>
<classLabel>hydrogen peroxide catabolic process</classLabel>
<deletedAxiom>&apos;hydrogen peroxide catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;hydrogen peroxide catabolic process&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042783</classIRI>
<classLabel>evasion of host immune response</classLabel>
<newAxiom>&apos;evasion of host immune response&apos; SubClassOf &apos;response to host immune response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042768</classIRI>
<classLabel>ecdysteroid 2-hydroxylase activity</classLabel>
<newAxiom>&apos;ecdysteroid 2-hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052168</classIRI>
<classLabel>modulation by symbiont of defense-related host calcium-dependent protein kinase pathway</classLabel>
<deletedAxiom>&apos;modulation by symbiont of defense-related host calcium-dependent protein kinase pathway&apos; SubClassOf &apos;symbiont-mediated perturbation of host defense response&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052150</classIRI>
<classLabel>symbiont-mediated perturbation of host apoptosis</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host apoptosis&apos; SubClassOf &apos;regulation of apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052151</classIRI>
<classLabel>symbiont-mediated activation of host apoptosis</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host apoptosis&apos; SubClassOf &apos;positive regulation of apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052167</classIRI>
<classLabel>symbiont-mediated perturbation of host innate immune response</classLabel>
<newAxiom>&apos;symbiont-mediated perturbation of host innate immune response&apos; SubClassOf &apos;symbiont-mediated perturbation of host defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052160</classIRI>
<classLabel>symbiont-mediated perturbation of host systemic acquired resistance</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host systemic acquired resistance&apos; SubClassOf &apos;symbiont-mediated perturbation of host immune response&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host systemic acquired resistance&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052162</classIRI>
<classLabel>modulation by symbiont of defense-related host calcium ion flux</classLabel>
<deletedAxiom>&apos;modulation by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;symbiont-mediated perturbation of host defense response&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of defense-related host calcium ion flux&apos; SubClassOf &apos;regulation of calcium-mediated signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001310</classIRI>
<classLabel>gliotoxin biosynthetic process</classLabel>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;disulfide oxidoreductase activity&apos;</newAxiom>
<newAxiom>&apos;gliotoxin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;acid-amino acid ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015066</classIRI>
<classLabel>alpha-amylase inhibitor activity</classLabel>
<newAxiom>&apos;alpha-amylase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;alpha-amylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030695</classIRI>
<classLabel>GTPase regulator activity</classLabel>
<newAxiom>&apos;GTPase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;GTPase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052026</classIRI>
<classLabel>symbiont-mediated perturbation of host transcription</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host gene expression&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated perturbation of host transcription&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052028</classIRI>
<classLabel>symbiont-mediated activation of host signal transduction pathway</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host signal transduction pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;signal transduction&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host signal transduction pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;signal transduction&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052031</classIRI>
<classLabel>symbiont-mediated perturbation of host defense response</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host defense response&apos; SubClassOf &apos;response to host defenses&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052038</classIRI>
<classLabel>symbiont-mediated perturbation of host intracellular transport</classLabel>
<deletedAxiom>&apos;symbiont-mediated perturbation of host intracellular transport&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;intracellular transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052042</classIRI>
<classLabel>symbiont-mediated activation of host programmed cell death</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host programmed cell death&apos; SubClassOf &apos;symbiont-mediated perturbation of host programmed cell death&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host programmed cell death&apos; SubClassOf &apos;positive regulation of killing of cells of another organism&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated activation of host programmed cell death&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052041</classIRI>
<classLabel>symbiont-mediated suppression of host programmed cell death</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host programmed cell death&apos; SubClassOf &apos;symbiont-mediated perturbation of host programmed cell death&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host programmed cell death&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001290</classIRI>
<classLabel>hydroperoxide metabolic process</classLabel>
<deletedAxiom>&apos;hydroperoxide metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;hydroperoxide metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001268</classIRI>
<classLabel>negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;negative regulation of apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902642</classIRI>
<classLabel>negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001267</classIRI>
<classLabel>regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001269</classIRI>
<classLabel>positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway</classLabel>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in apoptotic signaling pathway&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001272</classIRI>
<classLabel>positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis</classLabel>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;positive regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001278</classIRI>
<classLabel>positive regulation of L-leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of L-leucine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001277</classIRI>
<classLabel>negative regulation of L-leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of L-leucine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001276</classIRI>
<classLabel>regulation of L-leucine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of L-leucine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of L-leucine biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001271</classIRI>
<classLabel>negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis</classLabel>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;negative regulation of execution phase of apoptosis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;negative regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001270</classIRI>
<classLabel>regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis</classLabel>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf &apos;regulation of cysteine-type endopeptidase activity involved in apoptotic process&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type endopeptidase activity involved in execution phase of apoptosis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001246</classIRI>
<classLabel>negative regulation of phosphatidylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylcholine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001245</classIRI>
<classLabel>regulation of phosphatidylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylcholine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001247</classIRI>
<classLabel>positive regulation of phosphatidylcholine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylcholine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030545</classIRI>
<classLabel>signaling receptor regulator activity</classLabel>
<newAxiom>&apos;signaling receptor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030546</classIRI>
<classLabel>signaling receptor activator activity</classLabel>
<newAxiom>&apos;signaling receptor activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030547</classIRI>
<classLabel>signaling receptor inhibitor activity</classLabel>
<newAxiom>&apos;signaling receptor inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030548</classIRI>
<classLabel>acetylcholine receptor regulator activity</classLabel>
<newAxiom>&apos;acetylcholine receptor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030549</classIRI>
<classLabel>acetylcholine receptor activator activity</classLabel>
<newAxiom>&apos;acetylcholine receptor activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030550</classIRI>
<classLabel>acetylcholine receptor inhibitor activity</classLabel>
<newAxiom>&apos;acetylcholine receptor inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;acetylcholine receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042557</classIRI>
<classLabel>eukaryotic elongation factor-2 kinase activator activity</classLabel>
<newAxiom>&apos;eukaryotic elongation factor-2 kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;elongation factor-2 kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042556</classIRI>
<classLabel>eukaryotic elongation factor-2 kinase regulator activity</classLabel>
<newAxiom>&apos;eukaryotic elongation factor-2 kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;elongation factor-2 kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902757</classIRI>
<classLabel>bis(molybdopterin guanine dinucleotide)molybdenum metabolic process</classLabel>
<deletedAxiom>&apos;bis(molybdopterin guanine dinucleotide)molybdenum metabolic process&apos; SubClassOf &apos;nucleotide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902758</classIRI>
<classLabel>bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process</classLabel>
<deletedAxiom>&apos;bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process&apos; SubClassOf &apos;nucleotide biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900052</classIRI>
<classLabel>regulation of retinoic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of retinoic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900053</classIRI>
<classLabel>negative regulation of retinoic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of retinoic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900054</classIRI>
<classLabel>positive regulation of retinoic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of retinoic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900080</classIRI>
<classLabel>positive regulation of arginine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of arginine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900081</classIRI>
<classLabel>regulation of arginine catabolic process</classLabel>
<deletedAxiom>&apos;regulation of arginine catabolic process&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030414</classIRI>
<classLabel>peptidase inhibitor activity</classLabel>
<newAxiom>&apos;peptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;peptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900082</classIRI>
<classLabel>negative regulation of arginine catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of arginine catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900079</classIRI>
<classLabel>regulation of arginine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of arginine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140883</classIRI>
<classLabel>induction by virus of host reticulophagy</classLabel>
<deletedAxiom>&apos;induction by virus of host reticulophagy&apos; SubClassOf &apos;induction by virus of host autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host reticulophagy&apos; EquivalentTo &apos;symbiont-mediated perturbation of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;reticulophagy&apos;)</deletedAxiom>
<deletedAxiom>&apos;induction by virus of host reticulophagy&apos; SubClassOf &apos;positive regulation of reticulophagy&apos;</deletedAxiom>
<newAxiom>&apos;induction by virus of host reticulophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
<newAxiom>&apos;induction by virus of host reticulophagy&apos; SubClassOf &apos;symbiont-mediated activation of host autophagy&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140878</classIRI>
<classLabel>griseofulvin biosynthetic process</classLabel>
<newAxiom>&apos;griseofulvin biosynthetic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140881</classIRI>
<classLabel>positive regulation terrein biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation terrein biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140871</classIRI>
<classLabel>repressor of RNA polymerase inhibitor activity</classLabel>
<newAxiom>&apos;repressor of RNA polymerase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA polymerase inhibitor activity&apos;</newAxiom>
<newAxiom>&apos;repressor of RNA polymerase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA polymerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140870</classIRI>
<classLabel>RNA polymerase inhibitor activity</classLabel>
<newAxiom>&apos;RNA polymerase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA polymerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019941</classIRI>
<classLabel>modification-dependent protein catabolic process</classLabel>
<newAxiom>&apos;modification-dependent protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;protein modification process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900177</classIRI>
<classLabel>regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900178</classIRI>
<classLabel>negative regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900179</classIRI>
<classLabel>positive regulation of aflatoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of aflatoxin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032923</classIRI>
<classLabel>organic phosphonate biosynthetic process</classLabel>
<deletedAxiom>&apos;organic phosphonate biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;organic phosphonate biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900184</classIRI>
<classLabel>negative regulation of xanthone-containing compound biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of xanthone-containing compound biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of xanthone-containing compound biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900185</classIRI>
<classLabel>positive regulation of xanthone-containing compound biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of xanthone-containing compound biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of xanthone-containing compound biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900196</classIRI>
<classLabel>regulation of penicillin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of penicillin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900197</classIRI>
<classLabel>negative regulation of penicillin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of penicillin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900198</classIRI>
<classLabel>positive regulation of penicillin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of penicillin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030337</classIRI>
<classLabel>DNA polymerase processivity factor activity</classLabel>
<newAxiom>&apos;DNA polymerase processivity factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA polymerase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042304</classIRI>
<classLabel>regulation of fatty acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of fatty acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140733</classIRI>
<classLabel>tRNA ligase activator activity</classLabel>
<newAxiom>&apos;tRNA ligase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;aminoacyl-tRNA ligase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140721</classIRI>
<classLabel>nuclease inhibitor activity</classLabel>
<newAxiom>&apos;nuclease inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;nuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030292</classIRI>
<classLabel>protein tyrosine kinase inhibitor activity</classLabel>
<newAxiom>&apos;protein tyrosine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030293</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase inhibitor activity</classLabel>
<newAxiom>&apos;transmembrane receptor protein tyrosine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030295</classIRI>
<classLabel>protein kinase activator activity</classLabel>
<newAxiom>&apos;protein kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030296</classIRI>
<classLabel>protein tyrosine kinase activator activity</classLabel>
<newAxiom>&apos;protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030297</classIRI>
<classLabel>transmembrane receptor protein tyrosine kinase activator activity</classLabel>
<newAxiom>&apos;transmembrane receptor protein tyrosine kinase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;transmembrane receptor protein tyrosine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030291</classIRI>
<classLabel>protein serine/threonine kinase inhibitor activity</classLabel>
<newAxiom>&apos;protein serine/threonine kinase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902948</classIRI>
<classLabel>negative regulation of tau-protein kinase activity</classLabel>
<deletedAxiom>&apos;negative regulation of tau-protein kinase activity&apos; SubClassOf &apos;negative regulation of protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of tau-protein kinase activity&apos; SubClassOf &apos;negative regulation of protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902947</classIRI>
<classLabel>regulation of tau-protein kinase activity</classLabel>
<deletedAxiom>&apos;regulation of tau-protein kinase activity&apos; SubClassOf &apos;regulation of protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of tau-protein kinase activity&apos; SubClassOf &apos;regulation of protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902949</classIRI>
<classLabel>positive regulation of tau-protein kinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of tau-protein kinase activity&apos; SubClassOf &apos;positive regulation of protein kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of tau-protein kinase activity&apos; SubClassOf &apos;positive regulation of protein serine/threonine kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902982</classIRI>
<classLabel>DNA strand elongation involved in premeiotic DNA replication</classLabel>
<newAxiom>&apos;DNA strand elongation involved in premeiotic DNA replication&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902983</classIRI>
<classLabel>DNA strand elongation involved in mitotic DNA replication</classLabel>
<newAxiom>&apos;DNA strand elongation involved in mitotic DNA replication&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902986</classIRI>
<classLabel>regulation of lysine biosynthetic process via aminoadipic acid</classLabel>
<deletedAxiom>&apos;regulation of lysine biosynthetic process via aminoadipic acid&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of lysine biosynthetic process via aminoadipic acid&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902987</classIRI>
<classLabel>negative regulation of lysine biosynthetic process via aminoadipic acid</classLabel>
<deletedAxiom>&apos;negative regulation of lysine biosynthetic process via aminoadipic acid&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900339</classIRI>
<classLabel>regulation of methane biosynthetic process from formic acid</classLabel>
<newAxiom>&apos;regulation of methane biosynthetic process from formic acid&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902963</classIRI>
<classLabel>negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;negative regulation of amyloid precursor protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;negative regulation of metalloendopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902973</classIRI>
<classLabel>mitotic DNA replication DNA ligation</classLabel>
<newAxiom>&apos;mitotic DNA replication DNA ligation&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902972</classIRI>
<classLabel>premeiotic DNA replication DNA ligation</classLabel>
<newAxiom>&apos;premeiotic DNA replication DNA ligation&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902975</classIRI>
<classLabel>mitotic DNA replication initiation</classLabel>
<newAxiom>&apos;mitotic DNA replication initiation&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902974</classIRI>
<classLabel>meiotic DNA replication initiation</classLabel>
<deletedAxiom>&apos;meiotic DNA replication initiation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;meiotic cell cycle&apos;</deletedAxiom>
<newAxiom>&apos;meiotic DNA replication initiation&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902979</classIRI>
<classLabel>mitotic DNA replication termination</classLabel>
<newAxiom>&apos;mitotic DNA replication termination&apos; SubClassOf &apos;mitotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902978</classIRI>
<classLabel>premeiotic DNA replication termination</classLabel>
<newAxiom>&apos;premeiotic DNA replication termination&apos; SubClassOf &apos;meiotic cell cycle process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019914</classIRI>
<classLabel>cyclin-dependent protein kinase activating kinase regulator activity</classLabel>
<newAxiom>&apos;cyclin-dependent protein kinase activating kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclin-dependent protein kinase activating kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150094</classIRI>
<classLabel>amyloid-beta clearance by cellular catabolic process</classLabel>
<deletedAxiom>&apos;amyloid-beta clearance by cellular catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;amyloid-beta clearance by cellular catabolic process&apos; SubClassOf &apos;amyloid-beta metabolic process&apos;</newAxiom>
<newAxiom>&apos;amyloid-beta clearance by cellular catabolic process&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150065</classIRI>
<classLabel>regulation of deacetylase activity</classLabel>
<deletedAxiom>&apos;regulation of deacetylase activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of deacetylase activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150067</classIRI>
<classLabel>regulation of tubulin deacetylase activity</classLabel>
<newAxiom>&apos;regulation of tubulin deacetylase activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150066</classIRI>
<classLabel>negative regulation of deacetylase activity</classLabel>
<deletedAxiom>&apos;negative regulation of deacetylase activity&apos; SubClassOf &apos;negative regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of deacetylase activity&apos; SubClassOf &apos;negative regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019834</classIRI>
<classLabel>phospholipase A2 inhibitor activity</classLabel>
<newAxiom>&apos;phospholipase A2 inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase A2 activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019828</classIRI>
<classLabel>aspartic-type endopeptidase inhibitor activity</classLabel>
<newAxiom>&apos;aspartic-type endopeptidase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;aspartic-type endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900261</classIRI>
<classLabel>positive regulation of RNA-dependent RNA polymerase activity</classLabel>
<deletedAxiom>&apos;positive regulation of RNA-dependent RNA polymerase activity&apos; SubClassOf &apos;regulation of RNA-dependent RNA polymerase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA-dependent RNA polymerase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA-dependent RNA polymerase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA-dependent RNA polymerase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA-dependent RNA polymerase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA-dependent RNA polymerase activity&apos; SubClassOf &apos;positive regulation of transferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019855</classIRI>
<classLabel>calcium channel inhibitor activity</classLabel>
<newAxiom>&apos;calcium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019869</classIRI>
<classLabel>chloride channel inhibitor activity</classLabel>
<newAxiom>&apos;chloride channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;chloride channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019870</classIRI>
<classLabel>potassium channel inhibitor activity</classLabel>
<newAxiom>&apos;potassium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019871</classIRI>
<classLabel>sodium channel inhibitor activity</classLabel>
<newAxiom>&apos;sodium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;sodium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019887</classIRI>
<classLabel>protein kinase regulator activity</classLabel>
<newAxiom>&apos;protein kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019888</classIRI>
<classLabel>protein phosphatase regulator activity</classLabel>
<newAxiom>&apos;protein phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phosphoprotein phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044831</classIRI>
<classLabel>modulation by virus of host cytokine production</classLabel>
<deletedAxiom>&apos;modulation by virus of host cytokine production&apos; EquivalentTo &apos;perturbation by virus of host immune response&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytokine production&apos;)</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytokine production&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host cytokine production&apos; SubClassOf &apos;symbiont-mediated perturbation of host gene expression&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005246</classIRI>
<classLabel>calcium channel regulator activity</classLabel>
<newAxiom>&apos;calcium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044833</classIRI>
<classLabel>modulation by virus of host protein transport</classLabel>
<deletedAxiom>&apos;modulation by virus of host protein transport&apos; SubClassOf &apos;modulation by virus of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by virus of host protein transport&apos; SubClassOf &apos;symbiont-mediated perturbation of host intracellular transport&apos;</deletedAxiom>
<newAxiom>&apos;modulation by virus of host protein transport&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044863</classIRI>
<classLabel>modulation by virus of host cell division</classLabel>
<newAxiom>&apos;modulation by virus of host cell division&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140659</classIRI>
<classLabel>cytoskeletal motor regulator activity</classLabel>
<newAxiom>&apos;cytoskeletal motor regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cytoskeletal motor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140656</classIRI>
<classLabel>endodeoxyribonuclease activator activity</classLabel>
<newAxiom>&apos;endodeoxyribonuclease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140661</classIRI>
<classLabel>cytoskeletal motor inhibitor activity</classLabel>
<newAxiom>&apos;cytoskeletal motor inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cytoskeletal motor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140660</classIRI>
<classLabel>cytoskeletal motor activator activity</classLabel>
<newAxiom>&apos;cytoskeletal motor activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cytoskeletal motor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030234</classIRI>
<classLabel>enzyme regulator activity</classLabel>
<newAxiom>&apos;enzyme regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030235</classIRI>
<classLabel>nitric-oxide synthase regulator activity</classLabel>
<newAxiom>&apos;nitric-oxide synthase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;nitric-oxide synthase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140631</classIRI>
<classLabel>aldehyde dehydrogenase (NAD+) inhibitor activity</classLabel>
<newAxiom>&apos;aldehyde dehydrogenase (NAD+) inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;aldehyde dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140629</classIRI>
<classLabel>small conductance calcium-activated potassium channel inhibitor activity</classLabel>
<newAxiom>&apos;small conductance calcium-activated potassium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;small conductance calcium-activated potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140628</classIRI>
<classLabel>outward rectifier potassium channel inhibitor activity</classLabel>
<newAxiom>&apos;outward rectifier potassium channel inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;outward rectifier potassium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030258</classIRI>
<classLabel>lipid modification</classLabel>
<deletedAxiom>&apos;lipid modification&apos; SubClassOf &apos;cellular lipid metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;lipid modification&apos; SubClassOf &apos;lipid metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140620</classIRI>
<classLabel>DNA strand exchange inhibitor activity</classLabel>
<newAxiom>&apos;DNA strand exchange inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;DNA strand exchange activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140626</classIRI>
<classLabel>opioid growth factor receptor signaling pathway</classLabel>
<newAxiom>&apos;opioid growth factor receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;opioid growth factor receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140619</classIRI>
<classLabel>DNA strand exchange activator activity</classLabel>
<newAxiom>&apos;DNA strand exchange activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;DNA strand exchange activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030249</classIRI>
<classLabel>guanylate cyclase regulator activity</classLabel>
<newAxiom>&apos;guanylate cyclase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;guanylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030250</classIRI>
<classLabel>guanylate cyclase activator activity</classLabel>
<newAxiom>&apos;guanylate cyclase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;guanylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030251</classIRI>
<classLabel>guanylate cyclase inhibitor activity</classLabel>
<newAxiom>&apos;guanylate cyclase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;guanylate cyclase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140608</classIRI>
<classLabel>cysteine-type endopeptidase activator activity</classLabel>
<newAxiom>&apos;cysteine-type endopeptidase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;cysteine-type endopeptidase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030284</classIRI>
<classLabel>nuclear estrogen receptor activity</classLabel>
<deletedAxiom>&apos;nuclear estrogen receptor activity&apos; SubClassOf &apos;nuclear steroid receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;nuclear estrogen receptor activity&apos; SubClassOf &apos;nuclear receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042182</classIRI>
<classLabel>ketone catabolic process</classLabel>
<deletedAxiom>&apos;ketone catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042181</classIRI>
<classLabel>ketone biosynthetic process</classLabel>
<deletedAxiom>&apos;ketone biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042180</classIRI>
<classLabel>cellular ketone metabolic process</classLabel>
<deletedAxiom>&apos;cellular ketone metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular ketone metabolic process&apos; SubClassOf &apos;small molecule metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;cellular ketone metabolic process&apos; SubClassOf &apos;metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042178</classIRI>
<classLabel>xenobiotic catabolic process</classLabel>
<deletedAxiom>&apos;xenobiotic catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;xenobiotic catabolic process&apos; SubClassOf &apos;catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042197</classIRI>
<classLabel>halogenated hydrocarbon metabolic process</classLabel>
<newAxiom>&apos;halogenated hydrocarbon metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900480</classIRI>
<classLabel>regulation of diacylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of diacylglycerol biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900481</classIRI>
<classLabel>negative regulation of diacylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of diacylglycerol biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900482</classIRI>
<classLabel>positive regulation of diacylglycerol biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of diacylglycerol biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900497</classIRI>
<classLabel>regulation of butyryl-CoA catabolic process to butanol</classLabel>
<deletedAxiom>&apos;regulation of butyryl-CoA catabolic process to butanol&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900498</classIRI>
<classLabel>negative regulation of butyryl-CoA catabolic process to butanol</classLabel>
<deletedAxiom>&apos;negative regulation of butyryl-CoA catabolic process to butanol&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900499</classIRI>
<classLabel>positive regulation of butyryl-CoA catabolic process to butanol</classLabel>
<deletedAxiom>&apos;positive regulation of butyryl-CoA catabolic process to butanol&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900468</classIRI>
<classLabel>regulation of phosphatidylserine biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of phosphatidylserine biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900469</classIRI>
<classLabel>negative regulation of phosphatidylserine biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylserine biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900470</classIRI>
<classLabel>positive regulation of phosphatidylserine biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of phosphatidylserine biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900380</classIRI>
<classLabel>negative regulation of asperthecin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of asperthecin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900381</classIRI>
<classLabel>positive regulation of asperthecin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of asperthecin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900395</classIRI>
<classLabel>negative regulation of kojic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of kojic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900396</classIRI>
<classLabel>positive regulation of kojic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of kojic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019747</classIRI>
<classLabel>regulation of isoprenoid metabolic process</classLabel>
<deletedAxiom>&apos;regulation of isoprenoid metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140594</classIRI>
<classLabel>xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity</classLabel>
<newAxiom>&apos;xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;xyloglucan-specific endo-beta-1,4-glucanase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140537</classIRI>
<classLabel>transcription regulator activator activity</classLabel>
<newAxiom>&apos;transcription regulator activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;transcription regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044760</classIRI>
<classLabel>modulation by symbiont of host cholinergic synaptic transmission</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host cholinergic synaptic transmission&apos; SubClassOf &apos;regulation of synaptic transmission, cholinergic&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044761</classIRI>
<classLabel>negative regulation by symbiont of host cholinergic synaptic transmission</classLabel>
<deletedAxiom>&apos;negative regulation by symbiont of host cholinergic synaptic transmission&apos; SubClassOf &apos;modulation by symbiont of host cholinergic synaptic transmission&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host cholinergic synaptic transmission&apos; SubClassOf &apos;negative regulation of synaptic transmission, cholinergic&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation by symbiont of host cholinergic synaptic transmission&apos; SubClassOf &apos;negative regulation by symbiont of host synaptic transmission&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation by symbiont of host cholinergic synaptic transmission&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044758</classIRI>
<classLabel>modulation by symbiont of host synaptic transmission</classLabel>
<deletedAxiom>&apos;modulation by symbiont of host synaptic transmission&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chemical synaptic transmission&apos;</deletedAxiom>
<deletedAxiom>&apos;modulation by symbiont of host synaptic transmission&apos; EquivalentTo &apos;symbiont-mediated perturbation of host cellular process&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chemical synaptic transmission&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017081</classIRI>
<classLabel>chloride channel regulator activity</classLabel>
<newAxiom>&apos;chloride channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chloride channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017080</classIRI>
<classLabel>sodium channel regulator activity</classLabel>
<newAxiom>&apos;sodium channel regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;sodium channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044692</classIRI>
<classLabel>exoribonuclease activator activity</classLabel>
<newAxiom>&apos;exoribonuclease activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA exonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042030</classIRI>
<classLabel>ATPase inhibitor activity</classLabel>
<newAxiom>&apos;ATPase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ATP-dependent activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900500</classIRI>
<classLabel>regulation of butyryl-CoA catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;regulation of butyryl-CoA catabolic process to butyrate&apos; SubClassOf &apos;regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900501</classIRI>
<classLabel>negative regulation of butyryl-CoA catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;negative regulation of butyryl-CoA catabolic process to butyrate&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900502</classIRI>
<classLabel>positive regulation of butyryl-CoA catabolic process to butyrate</classLabel>
<deletedAxiom>&apos;positive regulation of butyryl-CoA catabolic process to butyrate&apos; SubClassOf &apos;positive regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900517</classIRI>
<classLabel>positive regulation of xylose catabolic process to ethanol</classLabel>
<deletedAxiom>&apos;positive regulation of xylose catabolic process to ethanol&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019650</classIRI>
<classLabel>glycolytic fermentation to butanediol</classLabel>
<newAxiom>&apos;glycolytic fermentation to butanediol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;(R,R)-butanediol dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019655</classIRI>
<classLabel>glycolytic fermentation to ethanol</classLabel>
<newAxiom>&apos;glycolytic fermentation to ethanol&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycolytic process through fructose-6-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019657</classIRI>
<classLabel>glycolytic fermentation to propionate</classLabel>
<newAxiom>&apos;glycolytic fermentation to propionate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;transport-coupled glycolytic process through glucose-6-phosphate&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019660</classIRI>
<classLabel>glycolytic fermentation</classLabel>
<newAxiom>&apos;glycolytic fermentation&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glycolytic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019661</classIRI>
<classLabel>glucose catabolic process to lactate via pyruvate</classLabel>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;L(+)-lactate biosynthetic process from pyruvate&apos;</newAxiom>
<newAxiom>&apos;glucose catabolic process to lactate via pyruvate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;canonical glycolysis&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140416</classIRI>
<classLabel>transcription regulator inhibitor activity</classLabel>
<newAxiom>&apos;transcription regulator inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;transcription regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017020</classIRI>
<classLabel>myosin phosphatase regulator activity</classLabel>
<newAxiom>&apos;myosin phosphatase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;myosin phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005085</classIRI>
<classLabel>guanyl-nucleotide exchange factor activity</classLabel>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;GDP binding&apos;</newAxiom>
<newAxiom>&apos;guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;GTP binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005095</classIRI>
<classLabel>GTPase inhibitor activity</classLabel>
<newAxiom>&apos;GTPase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;GTPase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005096</classIRI>
<classLabel>GTPase activator activity</classLabel>
<newAxiom>&apos;GTPase activator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;GTPase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900646</classIRI>
<classLabel>regulation of chanoclavine-I aldehyde biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of chanoclavine-I aldehyde biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900647</classIRI>
<classLabel>negative regulation of chanoclavine-I aldehyde biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of chanoclavine-I aldehyde biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900648</classIRI>
<classLabel>positive regulation of chanoclavine-I aldehyde biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of chanoclavine-I aldehyde biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900683</classIRI>
<classLabel>regulation of fumonisin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of fumonisin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of fumonisin biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900684</classIRI>
<classLabel>negative regulation of fumonisin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of fumonisin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900685</classIRI>
<classLabel>positive regulation of fumonisin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of fumonisin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900686</classIRI>
<classLabel>regulation of gerfelin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of gerfelin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of gerfelin biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900687</classIRI>
<classLabel>negative regulation of gerfelin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of gerfelin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900688</classIRI>
<classLabel>positive regulation of gerfelin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of gerfelin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900689</classIRI>
<classLabel>regulation of gliotoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900690</classIRI>
<classLabel>negative regulation of gliotoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900691</classIRI>
<classLabel>positive regulation of gliotoxin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of gliotoxin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900698</classIRI>
<classLabel>regulation of o-orsellinic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of o-orsellinic acid biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of o-orsellinic acid biosynthetic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900699</classIRI>
<classLabel>negative regulation of o-orsellinic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of o-orsellinic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900665</classIRI>
<classLabel>negative regulation of emodin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of emodin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900666</classIRI>
<classLabel>positive regulation of emodin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of emodin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900668</classIRI>
<classLabel>negative regulation of endocrocin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of endocrocin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900669</classIRI>
<classLabel>positive regulation of endocrocin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of endocrocin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140380</classIRI>
<classLabel>psilocybin biosynthetic process</classLabel>
<newAxiom>&apos;psilocybin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;4-hydroxytryptamine 4-phosphate methyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;psilocybin biosynthetic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;L-tryptophan decarboxylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140321</classIRI>
<classLabel>symbiont-mediated suppression of host autophagy</classLabel>
<deletedAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host autophagy&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;autophagy&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated suppression of host autophagy&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019574</classIRI>
<classLabel>sucrose catabolic process via 3&apos;-ketosucrose</classLabel>
<newAxiom>&apos;sucrose catabolic process via 3&apos;-ketosucrose&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;glucoside 3-dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044542</classIRI>
<classLabel>symbiont-mediated activation of host plasminogen</classLabel>
<deletedAxiom>&apos;symbiont-mediated activation of host plasminogen&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;plasminogen activation&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host plasminogen&apos; SubClassOf &apos;symbiont-mediated perturbation of host cellular process&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host plasminogen&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;plasminogen activation&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-mediated activation of host plasminogen&apos; SubClassOf &apos;zymogen activation in another organism&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-mediated activation of host plasminogen&apos; SubClassOf &apos;symbiont-mediated perturbation of host process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044544</classIRI>
<classLabel>envenomation resulting in plasminogen activation in another organism</classLabel>
<deletedAxiom>&apos;envenomation resulting in plasminogen activation in another organism&apos; EquivalentTo &apos;envenomation resulting in modulation of process in another organism&apos; and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;fibrinolysis&apos;) and (http://purl.obolibrary.org/obo/BFO_0000051 some &apos;symbiont-mediated activation of host plasminogen&apos;)</deletedAxiom>
<deletedAxiom>&apos;envenomation resulting in plasminogen activation in another organism&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;symbiont-mediated activation of host plasminogen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900733</classIRI>
<classLabel>negative regulation of polyketide biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of polyketide biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900734</classIRI>
<classLabel>positive regulation of polyketide biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of polyketide biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900700</classIRI>
<classLabel>positive regulation of o-orsellinic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of o-orsellinic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900708</classIRI>
<classLabel>negative regulation of tensidol A biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of tensidol A biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900709</classIRI>
<classLabel>positive regulation of tensidol A biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of tensidol A biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900711</classIRI>
<classLabel>negative regulation of tensidol B biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of tensidol B biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900712</classIRI>
<classLabel>positive regulation of tensidol B biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of tensidol B biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900760</classIRI>
<classLabel>negative regulation of sterigmatocystin biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of sterigmatocystin biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019420</classIRI>
<classLabel>dissimilatory sulfate reduction</classLabel>
<newAxiom>&apos;dissimilatory sulfate reduction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;dissimilatory sulfite reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032443</classIRI>
<classLabel>regulation of ergosterol biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of ergosterol biosynthetic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900841</classIRI>
<classLabel>negative regulation of helvolic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of helvolic acid biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900842</classIRI>
<classLabel>positive regulation of helvolic acid biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of helvolic acid biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900844</classIRI>
<classLabel>negative regulation of monodictyphenone biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of monodictyphenone biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900845</classIRI>
<classLabel>positive regulation of monodictyphenone biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of monodictyphenone biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900847</classIRI>
<classLabel>negative regulation of naphtho-gamma-pyrone biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of naphtho-gamma-pyrone biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of naphtho-gamma-pyrone biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900848</classIRI>
<classLabel>positive regulation of naphtho-gamma-pyrone biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of naphtho-gamma-pyrone biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of naphtho-gamma-pyrone biosynthetic process&apos; SubClassOf &apos;positive regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032346</classIRI>
<classLabel>positive regulation of aldosterone metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of aldosterone metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032353</classIRI>
<classLabel>negative regulation of hormone biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of hormone biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of hormone biosynthetic process&apos; SubClassOf &apos;negative regulation of biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900854</classIRI>
<classLabel>positive regulation of terrequinone A biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of terrequinone A biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071999</classIRI>
<classLabel>extracellular polysaccharide catabolic process</classLabel>
<deletedAxiom>&apos;extracellular polysaccharide catabolic process&apos; SubClassOf &apos;polysaccharide catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;extracellular polysaccharide catabolic process&apos; SubClassOf &apos;extracellular polysaccharide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900890</classIRI>
<classLabel>regulation of pentadecane metabolic process</classLabel>
<deletedAxiom>&apos;regulation of pentadecane metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of pentadecane metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900891</classIRI>
<classLabel>negative regulation of pentadecane metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of pentadecane metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of pentadecane metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900892</classIRI>
<classLabel>positive regulation of pentadecane metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of pentadecane metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of pentadecane metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900893</classIRI>
<classLabel>regulation of tridecane metabolic process</classLabel>
<deletedAxiom>&apos;regulation of tridecane metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of tridecane metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900894</classIRI>
<classLabel>negative regulation of tridecane metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of tridecane metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of tridecane metabolic process&apos; SubClassOf &apos;negative regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900895</classIRI>
<classLabel>positive regulation of tridecane metabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of tridecane metabolic process&apos; SubClassOf &apos;positive regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of tridecane metabolic process&apos; SubClassOf &apos;positive regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900899</classIRI>
<classLabel>regulation of heptadecane metabolic process</classLabel>
<deletedAxiom>&apos;regulation of heptadecane metabolic process&apos; SubClassOf &apos;regulation of cellular metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;regulation of heptadecane metabolic process&apos; SubClassOf &apos;regulation of metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010900</classIRI>
<classLabel>negative regulation of phosphatidylcholine catabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of phosphatidylcholine catabolic process&apos; SubClassOf &apos;negative regulation of cellular catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010919</classIRI>
<classLabel>regulation of inositol phosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of inositol phosphate biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010913</classIRI>
<classLabel>regulation of sterigmatocystin biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of sterigmatocystin biosynthetic process&apos; SubClassOf &apos;regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010914</classIRI>
<classLabel>positive regulation of sterigmatocystin biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of sterigmatocystin biosynthetic process&apos; SubClassOf &apos;positive regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010920</classIRI>
<classLabel>negative regulation of inositol phosphate biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of inositol phosphate biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010957</classIRI>
<classLabel>negative regulation of vitamin D biosynthetic process</classLabel>
<deletedAxiom>&apos;negative regulation of vitamin D biosynthetic process&apos; SubClassOf &apos;negative regulation of cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046910</classIRI>
<classLabel>pectinesterase inhibitor activity</classLabel>
<newAxiom>&apos;pectinesterase inhibitor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;pectinesterase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0007340</classIRI>
<classLabel>acrosome reaction</classLabel>
<newAxiom>&apos;acrosome reaction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;acrosomal vesicle exocytosis&apos;</newAxiom>
<newAxiom>&apos;acrosome reaction&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;membrane fusion involved in acrosome reaction&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046935</classIRI>
<classLabel>1-phosphatidylinositol-3-kinase regulator activity</classLabel>
<newAxiom>&apos;1-phosphatidylinositol-3-kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;1-phosphatidylinositol-3-kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071922</classIRI>
<classLabel>regulation of cohesin loading</classLabel>
<deletedAxiom>&apos;regulation of cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cohesin loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin loading&apos; SubClassOf &apos;regulation of sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of cohesin loading&apos; SubClassOf &apos;regulation of protein localization to chromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071921</classIRI>
<classLabel>cohesin loading</classLabel>
<deletedAxiom>&apos;cohesin loading&apos; SubClassOf &apos;cell cycle process&apos;</deletedAxiom>
<deletedAxiom>&apos;cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;establishment of sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;cohesin loading&apos; SubClassOf &apos;protein localization to chromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071923</classIRI>
<classLabel>negative regulation of cohesin loading</classLabel>
<deletedAxiom>&apos;negative regulation of cohesin loading&apos; SubClassOf &apos;regulation of cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin loading&apos; SubClassOf &apos;negative regulation of sister chromatid cohesion&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin loading&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cohesin loading&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin loading&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cohesin loading&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cohesin loading&apos; SubClassOf &apos;negative regulation of protein localization to chromatin&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034979</classIRI>
<classLabel>NAD-dependent protein lysine deacetylase activity</classLabel>
<deletedAxiom>&apos;NAD-dependent protein lysine deacetylase activity&apos; SubClassOf &apos;protein lysine deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;NAD-dependent protein lysine deacetylase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0141218</newAxiom>
<newAxiom>&apos;NAD-dependent protein lysine deacetylase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046951</classIRI>
<classLabel>ketone body biosynthetic process</classLabel>
<deletedAxiom>&apos;ketone body biosynthetic process&apos; SubClassOf &apos;cellular ketone body metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ketone body biosynthetic process&apos; SubClassOf &apos;cellular biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046950</classIRI>
<classLabel>cellular ketone body metabolic process</classLabel>
<deletedAxiom>&apos;cellular ketone body metabolic process&apos; SubClassOf &apos;cellular metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cellular ketone body metabolic process&apos; SubClassOf &apos;small molecule metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046952</classIRI>
<classLabel>ketone body catabolic process</classLabel>
<deletedAxiom>&apos;ketone body catabolic process&apos; SubClassOf &apos;cellular catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;ketone body catabolic process&apos; SubClassOf &apos;cellular ketone body metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900816</classIRI>
<classLabel>ochratoxin A metabolic process</classLabel>
<newAxiom>&apos;ochratoxin A metabolic process&apos; SubClassOf &apos;cellular organohalogen metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103105</classIRI>
<classLabel>2-oxo-6-methylthiohexanoate aminotransferase activity</classLabel>
<deletedAxiom>&apos;2-oxo-6-methylthiohexanoate aminotransferase activity&apos; SubClassOf &apos;transaminase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103104</classIRI>
<classLabel>6-methylthiohexyldesulfoglucosinolate sulfotransferase activity</classLabel>
<deletedAxiom>&apos;6-methylthiohexyldesulfoglucosinolate sulfotransferase activity&apos; SubClassOf &apos;sulfotransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032345</classIRI>
<classLabel>negative regulation of aldosterone metabolic process</classLabel>
<deletedAxiom>&apos;negative regulation of aldosterone metabolic process&apos; SubClassOf &apos;negative regulation of cellular metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032344</classIRI>
<classLabel>regulation of aldosterone metabolic process</classLabel>
<newAxiom>&apos;regulation of aldosterone metabolic process&apos; SubClassOf &apos;regulation of small molecule metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046970</classIRI>
<classLabel>NAD-dependent histone H4K16 deacetylase activity</classLabel>
<deletedAxiom>&apos;NAD-dependent histone H4K16 deacetylase activity&apos; SubClassOf &apos;histone H4K16 deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;NAD-dependent histone H4K16 deacetylase activity&apos; SubClassOf &apos;histone H4K deacetylase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046969</classIRI>
<classLabel>NAD-dependent histone H3K9 deacetylase activity</classLabel>
<deletedAxiom>&apos;NAD-dependent histone H3K9 deacetylase activity&apos; SubClassOf &apos;histone H3K9 deacetylase activity&apos;</deletedAxiom>
<newAxiom>&apos;NAD-dependent histone H3K9 deacetylase activity&apos; SubClassOf &apos;histone H3K deacetylase activity&apos;</newAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120530</classIRI>
<classLabel>UDP-alpha-D-glucose biosynthetic process</classLabel>
<newAxiom>'UDP-alpha-D-glucose biosynthetic process' SubClassOf 'nucleotide-sugar biosynthetic process'</newAxiom>
<newAxiom>'UDP-alpha-D-glucose biosynthetic process' SubClassOf 'UDP-alpha-D-glucose metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160217</classIRI>
<classLabel>negative regulation of transcription initiation-coupled chromatin remodeling</classLabel>
<newAxiom>'negative regulation of transcription initiation-coupled chromatin remodeling' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'transcription initiation-coupled chromatin remodeling'</newAxiom>
<newAxiom>'negative regulation of transcription initiation-coupled chromatin remodeling' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'transcription initiation-coupled chromatin remodeling')</newAxiom>
<newAxiom>'negative regulation of transcription initiation-coupled chromatin remodeling' SubClassOf 'regulation of gene expression'</newAxiom>
<newAxiom>'negative regulation of transcription initiation-coupled chromatin remodeling' SubClassOf 'negative regulation of chromatin organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160216</classIRI>
<classLabel>protein lysine delactylase activity</classLabel>
<newAxiom>'protein lysine delactylase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'protein lysine delactylase activity' SubClassOf 'deacylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160215</classIRI>
<classLabel>deacylase activity</classLabel>
<newAxiom>'deacylase activity' SubClassOf 'catalytic activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160214</classIRI>
<classLabel>endoplasmic reticulum-plasma membrane adaptor activity</classLabel>
<newAxiom>'endoplasmic reticulum-plasma membrane adaptor activity' SubClassOf 'protein-membrane adaptor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160213</classIRI>
<classLabel>beta-arrestin-dependent dopamine receptor signaling pathway</classLabel>
<newAxiom>'beta-arrestin-dependent dopamine receptor signaling pathway' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cellular response to dopamine'</newAxiom>
<newAxiom>'beta-arrestin-dependent dopamine receptor signaling pathway' SubClassOf 'cell surface receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160212</classIRI>
<classLabel>glycine-gated cation channel activity</classLabel>
<newAxiom>'glycine-gated cation channel activity' SubClassOf 'ligand-gated monoatomic cation channel activity'</newAxiom>
<newAxiom>'glycine-gated cation channel activity' SubClassOf 'transmitter-gated monoatomic ion channel activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160218</classIRI>
<classLabel>negative regulation of acetyl-CoA biosynthetic process from pyruvate</classLabel>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of sulfur metabolic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' EquivalentTo 'biological regulation' and (http://purl.obolibrary.org/obo/RO_0002212 some 'acetyl-CoA biosynthetic process from pyruvate')</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of phosphate metabolic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of biosynthetic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some 'acetyl-CoA biosynthetic process from pyruvate'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of small molecule metabolic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of amide metabolic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'negative regulation of nucleobase-containing compound metabolic process'</newAxiom>
<newAxiom>'negative regulation of acetyl-CoA biosynthetic process from pyruvate' SubClassOf 'regulation of acetyl-CoA biosynthetic process from pyruvate'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170061</classIRI>
<classLabel>nickel chaperone activity</classLabel>
<newAxiom>'nickel chaperone activity' SubClassOf 'metallochaperone activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170060</classIRI>
<classLabel>microtubule destablizing activity</classLabel>
<newAxiom>'microtubule destablizing activity' SubClassOf 'protein-containing complex destabilizing activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180048</classIRI>
<classLabel>phosphatidylinositol 4-phosphate biosynthetic process</classLabel>
<newAxiom>'phosphatidylinositol 4-phosphate biosynthetic process' SubClassOf 'biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180047</classIRI>
<classLabel>dolichol phosphate mannose biosynthetic process</classLabel>
<newAxiom>'dolichol phosphate mannose biosynthetic process' SubClassOf 'biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141218</classIRI>
<classLabel>NAD-dependent protein lysine deacylase activity</classLabel>
<newAxiom>'NAD-dependent protein lysine deacylase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'NAD-dependent protein lysine deacylase activity' SubClassOf 'deacetylase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141217</classIRI>
<classLabel>RNA glycosylation</classLabel>
<newAxiom>'RNA glycosylation' SubClassOf 'RNA processing'</newAxiom>
<newAxiom>'RNA glycosylation' SubClassOf 'glycosylation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141223</classIRI>
<classLabel>cysteine synthase activity, acting on O-succinyl-L-serine</classLabel>
<newAxiom>'cysteine synthase activity, acting on O-succinyl-L-serine' SubClassOf 'transferase activity, transferring alkyl or aryl (other than methyl) groups'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141222</classIRI>
<classLabel>histone H3K4 deacetylase activity, NAD-dependent</classLabel>
<newAxiom>'histone H3K4 deacetylase activity, NAD-dependent' SubClassOf 'histone H3K deacetylase activity'</newAxiom>
<newAxiom>'histone H3K4 deacetylase activity, NAD-dependent' SubClassOf 'histone deacetylase activity, NAD-dependent'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141221</classIRI>
<classLabel>histone deacetylase activity, hydrolytic mechanism</classLabel>
<newAxiom>'histone deacetylase activity, hydrolytic mechanism' SubClassOf 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides'</newAxiom>
<newAxiom>'histone deacetylase activity, hydrolytic mechanism' SubClassOf 'histone deacetylase activity'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>