<?xml version="1.0"?>
<diffReport>
<diffSummary>
<numberChangedClasses>
478
</numberChangedClasses>
<numberNewClasses>
71
</numberNewClasses>
<numberDeletedClasses>
0
</numberDeletedClasses>
</diffSummary>
<changedClasses>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019280</classIRI>
<classLabel>L-methionine biosynthetic process from L-homoserine via O-acetyl-L-homoserine</classLabel>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via O-acetyl-L-homoserine&apos; SubClassOf &apos;non-proteinogenic amino acid metabolic process&apos;</newAxiom>
<newAxiom>&apos;L-methionine biosynthetic process from L-homoserine via O-acetyl-L-homoserine&apos; SubClassOf &apos;L-methionine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032296</classIRI>
<classLabel>double-stranded RNA-specific ribonuclease activity</classLabel>
<newAxiom>&apos;double-stranded RNA-specific ribonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140021</classIRI>
<classLabel>mitochondrial ADP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ADP transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0103036</classIRI>
<classLabel>NADH:menaquinone oxidoreductase activity</classLabel>
<deletedAxiom>&apos;NADH:menaquinone oxidoreductase activity&apos; SubClassOf &apos;NADH dehydrogenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NADH:menaquinone oxidoreductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;NADH:menaquinone oxidoreductase activity&apos; SubClassOf &apos;NADH:ubiquinone reductase (non-electrogenic) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019206</classIRI>
<classLabel>nucleoside kinase activity</classLabel>
<newAxiom>&apos;nucleoside kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0022871</classIRI>
<classLabel>protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity</classLabel>
<deletedAxiom>&apos;protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity&apos; SubClassOf &apos;sorbose transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019194</classIRI>
<classLabel>sorbose transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;sorbose transmembrane transporter activity&apos; SubClassOf &apos;hexose transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010722</classIRI>
<classLabel>regulation of ferrochelatase activity</classLabel>
<deletedAxiom>&apos;regulation of ferrochelatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ferrochelatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ferrochelatase activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ferrochelatase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;ferrochelatase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000984</classIRI>
<classLabel>negative regulation of ATP citrate synthase activity</classLabel>
<deletedAxiom>&apos;negative regulation of ATP citrate synthase activity&apos; SubClassOf &apos;negative regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ATP citrate synthase activity&apos; SubClassOf &apos;regulation of ATP citrate synthase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ATP citrate synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;ATP citrate synthase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ATP citrate synthase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;ATP citrate synthase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000969</classIRI>
<classLabel>positive regulation of AMPA receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of AMPA receptor activity&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019136</classIRI>
<classLabel>deoxynucleoside kinase activity</classLabel>
<deletedAxiom>&apos;deoxynucleoside kinase activity&apos; SubClassOf &apos;nucleoside kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;deoxynucleoside kinase activity&apos; SubClassOf &apos;nucleobase-containing compound kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020006</classIRI>
<classLabel>symbiont-containing vacuolar membrane network</classLabel>
<deletedAxiom>&apos;symbiont-containing vacuolar membrane network&apos; SubClassOf &apos;host cell part&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-containing vacuolar membrane network&apos; SubClassOf &apos;cellular anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020004</classIRI>
<classLabel>symbiont-containing vacuolar space</classLabel>
<deletedAxiom>&apos;symbiont-containing vacuolar space&apos; SubClassOf &apos;host cell part&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-containing vacuolar space&apos; SubClassOf &apos;membrane-enclosed lumen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020005</classIRI>
<classLabel>symbiont-containing vacuole membrane</classLabel>
<deletedAxiom>&apos;symbiont-containing vacuole membrane&apos; SubClassOf &apos;host cell part&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-containing vacuole membrane&apos; SubClassOf &apos;organelle membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020026</classIRI>
<classLabel>merozoite dense granule</classLabel>
<deletedAxiom>&apos;merozoite dense granule&apos; SubClassOf &apos;cytoplasmic vesicle&apos;</deletedAxiom>
<newAxiom>&apos;merozoite dense granule&apos; SubClassOf &apos;secretory granule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032075</classIRI>
<classLabel>positive regulation of nuclease activity</classLabel>
<deletedAxiom>&apos;positive regulation of nuclease activity&apos; SubClassOf &apos;positive regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of nuclease activity&apos; SubClassOf &apos;positive regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032074</classIRI>
<classLabel>negative regulation of nuclease activity</classLabel>
<deletedAxiom>&apos;negative regulation of nuclease activity&apos; SubClassOf &apos;negative regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of nuclease activity&apos; SubClassOf &apos;negative regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032071</classIRI>
<classLabel>regulation of endodeoxyribonuclease activity</classLabel>
<deletedAxiom>&apos;regulation of endodeoxyribonuclease activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of endodeoxyribonuclease activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032072</classIRI>
<classLabel>regulation of restriction endodeoxyribonuclease activity</classLabel>
<newAxiom>&apos;regulation of restriction endodeoxyribonuclease activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034603</classIRI>
<classLabel>pyruvate dehydrogenase [NAD(P)+] activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;pyruvate dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034604</classIRI>
<classLabel>pyruvate dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (NAD+) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate dehydrogenase (acetyl-transferring) activity&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate dehydrogenase (NAD+) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;dihydrolipoyllysine-residue acetyltransferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate dehydrogenase (NAD+) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;pyruvate decarboxylation to acetyl-CoA&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate dehydrogenase (NAD+) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;dihydrolipoyl dehydrogenase (NADH) activity&apos;</deletedAxiom>
<deletedAxiom>&apos;pyruvate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;pyruvate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034601</classIRI>
<classLabel>oxoglutarate dehydrogenase [NAD(P)+] activity</classLabel>
<deletedAxiom>&apos;oxoglutarate dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034602</classIRI>
<classLabel>oxoglutarate dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;oxoglutarate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxoglutarate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034610</classIRI>
<classLabel>oligodeoxyribonucleotidase activity</classLabel>
<deletedAxiom>&apos;oligodeoxyribonucleotidase activity&apos; SubClassOf &apos;oligonucleotidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;oligodeoxyribonucleotidase activity&apos; SubClassOf &apos;DNA nuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034611</classIRI>
<classLabel>oligoribonucleotidase activity</classLabel>
<deletedAxiom>&apos;oligoribonucleotidase activity&apos; SubClassOf &apos;RNA nuclease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;oligoribonucleotidase activity&apos; SubClassOf &apos;oligonucleotidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0020003</classIRI>
<classLabel>symbiont-containing vacuole</classLabel>
<deletedAxiom>&apos;symbiont-containing vacuole&apos; SubClassOf &apos;extracellular membrane-bounded organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;symbiont-containing vacuole&apos; SubClassOf &apos;host cell cytoplasm part&apos;</deletedAxiom>
<newAxiom>&apos;symbiont-containing vacuole&apos; SubClassOf &apos;cellular anatomical structure&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046589</classIRI>
<classLabel>ribonuclease T1 activity</classLabel>
<deletedAxiom>&apos;ribonuclease T1 activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease T1 activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
<newAxiom>&apos;ribonuclease T1 activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010519</classIRI>
<classLabel>negative regulation of phospholipase activity</classLabel>
<deletedAxiom>&apos;negative regulation of phospholipase activity&apos; SubClassOf &apos;regulation of phospholipase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phospholipase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phospholipase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;phospholipase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phospholipase activity&apos; SubClassOf &apos;negative regulation of lipase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034317</classIRI>
<classLabel>nicotinate riboside kinase activity</classLabel>
<deletedAxiom>&apos;nicotinate riboside kinase activity&apos; SubClassOf &apos;nucleoside kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;nicotinate riboside kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009381</classIRI>
<classLabel>excinuclease ABC activity</classLabel>
<newAxiom>&apos;excinuclease ABC activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061974</classIRI>
<classLabel>perichondral bone morphogenesis</classLabel>
<deletedAxiom>&apos;perichondral bone morphogenesis&apos; SubClassOf &apos;endochondral bone morphogenesis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0071254</classIRI>
<classLabel>cytoplasmic U snRNP body</classLabel>
<deletedAxiom>&apos;cytoplasmic U snRNP body&apos; SubClassOf &apos;ribonucleoprotein complex&apos;</deletedAxiom>
<deletedAxiom>&apos;cytoplasmic U snRNP body&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytoplasm&apos;</deletedAxiom>
<newAxiom>&apos;cytoplasmic U snRNP body&apos; SubClassOf &apos;cytoplasmic ribonucleoprotein granule&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010122</classIRI>
<classLabel>arginine catabolic process to alanine via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;arginine catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;arginine metabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to alanine via ornithine&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010121</classIRI>
<classLabel>arginine catabolic process to proline via ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to proline via ornithine&apos; SubClassOf &apos;arginine catabolic process to proline&apos;</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to proline via ornithine&apos; SubClassOf &apos;arginine catabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to proline via ornithine&apos; SubClassOf &apos;proline metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061722</classIRI>
<classLabel>sulphoglycolysis</classLabel>
<deletedAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;NADH metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;sulphoglycolysis&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046117</classIRI>
<classLabel>queuosine catabolic process</classLabel>
<deletedAxiom>&apos;queuosine catabolic process&apos; SubClassOf &apos;queuosine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;queuosine catabolic process&apos; SubClassOf &apos;ribonucleoside catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046116</classIRI>
<classLabel>queuosine metabolic process</classLabel>
<deletedAxiom>&apos;queuosine metabolic process&apos; SubClassOf &apos;ribonucleoside metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046089</classIRI>
<classLabel>cytosine biosynthetic process</classLabel>
<deletedAxiom>&apos;cytosine biosynthetic process&apos; SubClassOf &apos;cytosine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cytosine biosynthetic process&apos; SubClassOf &apos;pyrimidine nucleobase biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046088</classIRI>
<classLabel>cytidine biosynthetic process</classLabel>
<deletedAxiom>&apos;cytidine biosynthetic process&apos; SubClassOf &apos;cytidine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cytidine biosynthetic process&apos; SubClassOf &apos;pyrimidine ribonucleoside biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009041</classIRI>
<classLabel>UMP/dUMP kinase activity</classLabel>
<deletedAxiom>&apos;UMP/dUMP kinase activity&apos; SubClassOf &apos;nucleobase-containing compound kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046027</classIRI>
<classLabel>phospholipid:diacylglycerol acyltransferase activity</classLabel>
<deletedAxiom>&apos;phospholipid:diacylglycerol acyltransferase activity&apos; SubClassOf &apos;N-acetyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;phospholipid:diacylglycerol acyltransferase activity&apos; SubClassOf &apos;acyltransferase activity, transferring groups other than amino-acyl groups&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046028</classIRI>
<classLabel>electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity</classLabel>
<deletedAxiom>&apos;electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity&apos; SubClassOf &apos;electron transfer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097619</classIRI>
<classLabel>PTEX complex</classLabel>
<deletedAxiom>&apos;PTEX complex&apos; SubClassOf &apos;protein-containing complex&apos;</deletedAxiom>
<newAxiom>&apos;PTEX complex&apos; SubClassOf &apos;membrane protein complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009091</classIRI>
<classLabel>homoserine catabolic process</classLabel>
<deletedAxiom>&apos;homoserine catabolic process&apos; SubClassOf &apos;serine family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;homoserine catabolic process&apos; SubClassOf &apos;carboxylic acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061621</classIRI>
<classLabel>canonical glycolysis</classLabel>
<deletedAxiom>&apos;canonical glycolysis&apos; SubClassOf &apos;NADH metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0034070</classIRI>
<classLabel>aminoglycoside 1-N-acetyltransferase activity</classLabel>
<deletedAxiom>&apos;aminoglycoside 1-N-acetyltransferase activity&apos; SubClassOf &apos;aminoglycoside N-acetyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000273</classIRI>
<classLabel>positive regulation of signaling receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;signaling receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of signaling receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000276</classIRI>
<classLabel>negative regulation of oxidative phosphorylation uncoupler activity</classLabel>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf &apos;negative regulation of cation transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf &apos;negative regulation of transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf &apos;regulation of transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;oxidative phosphorylation uncoupler activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of oxidative phosphorylation uncoupler activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;oxidative phosphorylation uncoupler activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000515</classIRI>
<classLabel>aspartate:glutamate, proton antiporter activity</classLabel>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;amino acid:monoatomic cation antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;C4-dicarboxylate transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;dicarboxylic acid transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;proton transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;L-aspartate transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;aspartate:glutamate, proton antiporter activity&apos; SubClassOf &apos;L-glutamate:proton antiporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061510</classIRI>
<classLabel>asymmetric protein localization to new mitotic spindle pole body</classLabel>
<deletedAxiom>&apos;asymmetric protein localization to new mitotic spindle pole body&apos; SubClassOf &apos;protein localization to mitotic spindle pole body&apos;</deletedAxiom>
<deletedAxiom>&apos;asymmetric protein localization to new mitotic spindle pole body&apos; SubClassOf &apos;asymmetric protein localization to old or new spindle pole body&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061509</classIRI>
<classLabel>asymmetric protein localization to old mitotic spindle pole body</classLabel>
<deletedAxiom>&apos;asymmetric protein localization to old mitotic spindle pole body&apos; SubClassOf &apos;asymmetric protein localization to old or new spindle pole body&apos;</deletedAxiom>
<deletedAxiom>&apos;asymmetric protein localization to old mitotic spindle pole body&apos; SubClassOf &apos;protein localization to mitotic spindle pole body&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000152</classIRI>
<classLabel>regulation of ubiquitin-specific protease activity</classLabel>
<deletedAxiom>&apos;regulation of ubiquitin-specific protease activity&apos; SubClassOf &apos;regulation of peptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-specific protease activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type deubiquitinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ubiquitin-specific protease activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;cysteine-type deubiquitinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000157</classIRI>
<classLabel>negative regulation of ubiquitin-specific protease activity</classLabel>
<deletedAxiom>&apos;negative regulation of ubiquitin-specific protease activity&apos; SubClassOf &apos;negative regulation of peptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-specific protease activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type deubiquitinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-specific protease activity&apos; SubClassOf &apos;regulation of ubiquitin-specific protease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of ubiquitin-specific protease activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cysteine-type deubiquitinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000158</classIRI>
<classLabel>positive regulation of ubiquitin-specific protease activity</classLabel>
<deletedAxiom>&apos;positive regulation of ubiquitin-specific protease activity&apos; SubClassOf &apos;regulation of ubiquitin-specific protease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061492</classIRI>
<classLabel>asymmetric protein localization to old or new spindle pole body</classLabel>
<deletedAxiom>&apos;asymmetric protein localization to old or new spindle pole body&apos; SubClassOf &apos;protein localization to spindle pole body&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036402</classIRI>
<classLabel>proteasome-activating activity</classLabel>
<deletedAxiom>&apos;proteasome-activating activity&apos; EquivalentTo &apos;ATP-dependent activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of proteasomal protein catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;proteasome-activating activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;positive regulation of proteasomal protein catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;proteasome-activating activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;proteasomal protein catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036444</classIRI>
<classLabel>calcium import into the mitochondrion</classLabel>
<deletedAxiom>&apos;calcium import into the mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036431</classIRI>
<classLabel>dCMP kinase activity</classLabel>
<deletedAxiom>&apos;dCMP kinase activity&apos; SubClassOf &apos;(d)CMP kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036430</classIRI>
<classLabel>CMP kinase activity</classLabel>
<deletedAxiom>&apos;CMP kinase activity&apos; SubClassOf &apos;(d)CMP kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120216</classIRI>
<classLabel>matrilin complex</classLabel>
<deletedAxiom>&apos;matrilin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;matrilin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160007</classIRI>
<classLabel>glutathione import into mitochondrion</classLabel>
<deletedAxiom>&apos;glutathione import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120127</classIRI>
<classLabel>response to zinc ion starvation</classLabel>
<deletedAxiom>&apos;response to zinc ion starvation&apos; SubClassOf &apos;response to starvation&apos;</deletedAxiom>
<newAxiom>&apos;response to zinc ion starvation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180055</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120126</classIRI>
<classLabel>response to copper ion starvation</classLabel>
<deletedAxiom>&apos;response to copper ion starvation&apos; SubClassOf &apos;response to starvation&apos;</deletedAxiom>
<newAxiom>&apos;response to copper ion starvation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180055</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120136</classIRI>
<classLabel>dUMP kinase activity</classLabel>
<deletedAxiom>&apos;dUMP kinase activity&apos; SubClassOf &apos;UMP/dUMP kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048256</classIRI>
<classLabel>flap endonuclease activity</classLabel>
<newAxiom>&apos;flap endonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0048250</classIRI>
<classLabel>iron import into the mitochondrion</classLabel>
<deletedAxiom>&apos;iron import into the mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000363</classIRI>
<classLabel>positive regulation of prostaglandin-E synthase activity</classLabel>
<deletedAxiom>&apos;positive regulation of prostaglandin-E synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;prostaglandin-E synthase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of prostaglandin-E synthase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;prostaglandin-E synthase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of prostaglandin-E synthase activity&apos; SubClassOf &apos;positive regulation of catalytic activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097256</classIRI>
<classLabel>phenyllactate dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;phenyllactate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;phenyllactate dehydrogenase (NAD+) activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160157</classIRI>
<classLabel>branched-chain alpha-ketoacid dehydrogenase complex</classLabel>
<newAxiom>&apos;branched-chain alpha-ketoacid dehydrogenase complex&apos; SubClassOf &apos;transferase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990042</classIRI>
<classLabel>glycerol dehydrogenase [NAD(P)+] activity</classLabel>
<deletedAxiom>&apos;glycerol dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036241</classIRI>
<classLabel>glutamate catabolic process to 4-hydroxybutyrate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to 4-hydroxybutyrate&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;4-hydroxybutyrate dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036188</classIRI>
<classLabel>abieta-7,13-dien-18-al dehydrogenase activity</classLabel>
<deletedAxiom>&apos;abieta-7,13-dien-18-al dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;abieta-7,13-dien-18-al dehydrogenase activity&apos; SubClassOf &apos;aldehyde dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0036191</classIRI>
<classLabel>indolin-2-one monooxygenase activity</classLabel>
<deletedAxiom>&apos;indolin-2-one monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen&apos;</deletedAxiom>
<newAxiom>&apos;indolin-2-one monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0097165</classIRI>
<classLabel>nuclear stress granule</classLabel>
<deletedAxiom>&apos;nuclear stress granule&apos; SubClassOf &apos;ribonucleoprotein granule&apos;</deletedAxiom>
<deletedAxiom>&apos;nuclear stress granule&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;nucleus&apos;</deletedAxiom>
<newAxiom>&apos;nuclear stress granule&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140168</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000650</classIRI>
<classLabel>negative regulation of sodium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of sodium ion transmembrane transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;sodium ion transmembrane transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sodium ion transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sodium ion transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sodium ion transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of sodium ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000213</classIRI>
<classLabel>tRNA-intron lyase activity</classLabel>
<deletedAxiom>&apos;tRNA-intron lyase activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;tRNA-intron lyase activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
<newAxiom>&apos;tRNA-intron lyase activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000657</classIRI>
<classLabel>negative regulation of apolipoprotein binding</classLabel>
<deletedAxiom>&apos;negative regulation of apolipoprotein binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;apolipoprotein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of apolipoprotein binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;apolipoprotein binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of apolipoprotein binding&apos; SubClassOf &apos;negative regulation of protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904042</classIRI>
<classLabel>negative regulation of cystathionine beta-synthase activity</classLabel>
<deletedAxiom>&apos;negative regulation of cystathionine beta-synthase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cystathionine beta-synthase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cystathionine beta-synthase activity&apos; SubClassOf &apos;negative regulation of lyase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cystathionine beta-synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cystathionine beta-synthase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904027</classIRI>
<classLabel>negative regulation of collagen fibril organization</classLabel>
<deletedAxiom>&apos;negative regulation of collagen fibril organization&apos; SubClassOf &apos;negative regulation of supramolecular fiber organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904026</classIRI>
<classLabel>regulation of collagen fibril organization</classLabel>
<deletedAxiom>&apos;regulation of collagen fibril organization&apos; SubClassOf &apos;regulation of supramolecular fiber organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904028</classIRI>
<classLabel>positive regulation of collagen fibril organization</classLabel>
<deletedAxiom>&apos;positive regulation of collagen fibril organization&apos; SubClassOf &apos;positive regulation of supramolecular fiber organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904182</classIRI>
<classLabel>regulation of pyruvate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;regulation of pyruvate dehydrogenase activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of pyruvate dehydrogenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;pyruvate dehydrogenase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of pyruvate dehydrogenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;pyruvate dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000171</classIRI>
<classLabel>ribonuclease MRP activity</classLabel>
<newAxiom>&apos;ribonuclease MRP activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0061077</classIRI>
<classLabel>chaperone-mediated protein folding</classLabel>
<deletedAxiom>&apos;chaperone-mediated protein folding&apos; SubClassOf &apos;protein folding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051607</classIRI>
<classLabel>defense response to virus</classLabel>
<deletedAxiom>&apos;defense response to virus&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to virus&apos; SubClassOf &apos;defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990229</classIRI>
<classLabel>iron-sulfur cluster assembly complex</classLabel>
<deletedAxiom>&apos;iron-sulfur cluster assembly complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytosol&apos;</deletedAxiom>
<newAxiom>&apos;iron-sulfur cluster assembly complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cytoplasm&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990238</classIRI>
<classLabel>double-stranded DNA endonuclease activity</classLabel>
<newAxiom>&apos;double-stranded DNA endonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051596</classIRI>
<classLabel>methylglyoxal catabolic process</classLabel>
<newAxiom>&apos;methylglyoxal catabolic process&apos; SubClassOf &apos;cellular detoxification of methylglyoxal&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990194</classIRI>
<classLabel>cytoplasmic U snRNP body assembly</classLabel>
<newAxiom>&apos;cytoplasmic U snRNP body assembly&apos; SubClassOf &apos;membraneless organelle assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0000014</classIRI>
<classLabel>single-stranded DNA endodeoxyribonuclease activity</classLabel>
<newAxiom>&apos;single-stranded DNA endodeoxyribonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904258</classIRI>
<classLabel>nuclear dicing body assembly</classLabel>
<deletedAxiom>&apos;nuclear dicing body assembly&apos; SubClassOf &apos;cellular component assembly&apos;</deletedAxiom>
<newAxiom>&apos;nuclear dicing body assembly&apos; SubClassOf &apos;membraneless organelle assembly&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904227</classIRI>
<classLabel>negative regulation of glycogen synthase activity, transferring glucose-1-phosphate</classLabel>
<deletedAxiom>&apos;negative regulation of glycogen synthase activity, transferring glucose-1-phosphate&apos; SubClassOf &apos;negative regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycogen synthase activity, transferring glucose-1-phosphate&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;glycogen synthase activity, transferring glucose-1-phosphate&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of glycogen synthase activity, transferring glucose-1-phosphate&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;glycogen synthase activity, transferring glucose-1-phosphate&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904234</classIRI>
<classLabel>positive regulation of aconitate hydratase activity</classLabel>
<deletedAxiom>&apos;positive regulation of aconitate hydratase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;aconitate hydratase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aconitate hydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;aconitate hydratase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aconitate hydratase activity&apos; SubClassOf &apos;positive regulation of lyase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904233</classIRI>
<classLabel>negative regulation of aconitate hydratase activity</classLabel>
<deletedAxiom>&apos;negative regulation of aconitate hydratase activity&apos; SubClassOf &apos;negative regulation of lyase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of aconitate hydratase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;aconitate hydratase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of aconitate hydratase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;aconitate hydratase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099535</classIRI>
<classLabel>synapse-associated extracellular matrix</classLabel>
<deletedAxiom>&apos;synapse-associated extracellular matrix&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000825</classIRI>
<classLabel>positive regulation of androgen receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of androgen receptor activity&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of androgen receptor activity&apos; SubClassOf &apos;regulation of signaling receptor activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990326</classIRI>
<classLabel>collagen type XXVIII trimer</classLabel>
<deletedAxiom>&apos;collagen type XXVIII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen type XXVIII trimer&apos; SubClassOf &apos;collagen trimer&apos;</deletedAxiom>
<newAxiom>&apos;collagen type XXVIII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140158</newAxiom>
<newAxiom>&apos;collagen type XXVIII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0140143</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990324</classIRI>
<classLabel>collagen type XXVI trimer</classLabel>
<deletedAxiom>&apos;collagen type XXVI trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;collagen type XXVI trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990318</classIRI>
<classLabel>collagen type XIX trimer</classLabel>
<deletedAxiom>&apos;collagen type XIX trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;basement membrane&apos;</deletedAxiom>
<newAxiom>&apos;collagen type XIX trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0140143</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990397</classIRI>
<classLabel>queuosine salvage</classLabel>
<deletedAxiom>&apos;queuosine salvage&apos; SubClassOf &apos;queuosine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;queuosine salvage&apos; SubClassOf &apos;nucleoside salvage&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990355</classIRI>
<classLabel>L-methionine salvage from methionine sulphoxide</classLabel>
<deletedAxiom>&apos;L-methionine salvage from methionine sulphoxide&apos; SubClassOf &apos;L-methionine salvage&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905778</classIRI>
<classLabel>negative regulation of exonuclease activity</classLabel>
<deletedAxiom>&apos;negative regulation of exonuclease activity&apos; SubClassOf &apos;negative regulation of nuclease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of exonuclease activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;exonuclease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of exonuclease activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;exonuclease activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051392</classIRI>
<classLabel>tRNA N4-acetyltransferase activity</classLabel>
<newAxiom>&apos;tRNA N4-acetyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110141</classIRI>
<classLabel>L-glutamate import into mitochondrion</classLabel>
<deletedAxiom>&apos;L-glutamate import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170046</classIRI>
<classLabel>isopentenyl pyrophosphate import into mitochondrion</classLabel>
<deletedAxiom>&apos;isopentenyl pyrophosphate import into mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;isopentenyl pyrophosphate import into mitochondrion&apos; SubClassOf &apos;organic anion transport&apos;</newAxiom>
<newAxiom>&apos;isopentenyl pyrophosphate import into mitochondrion&apos; SubClassOf &apos;intracellular lipid transport&apos;</newAxiom>
<newAxiom>&apos;isopentenyl pyrophosphate import into mitochondrion&apos; SubClassOf &apos;phospholipid transport&apos;</newAxiom>
<newAxiom>&apos;isopentenyl pyrophosphate import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110113</classIRI>
<classLabel>positive regulation of lipid transporter activity</classLabel>
<deletedAxiom>&apos;positive regulation of lipid transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;lipid transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid transporter activity&apos; SubClassOf &apos;positive regulation of transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid transporter activity&apos; SubClassOf &apos;positive regulation of lipid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of lipid transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;lipid transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0110114</classIRI>
<classLabel>negative regulation of lipid transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of lipid transporter activity&apos; SubClassOf &apos;negative regulation of transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid transporter activity&apos; SubClassOf &apos;negative regulation of lipid transport&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;lipid transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of lipid transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;lipid transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905919</classIRI>
<classLabel>negative regulation of CoA-transferase activity</classLabel>
<deletedAxiom>&apos;negative regulation of CoA-transferase activity&apos; SubClassOf &apos;negative regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of CoA-transferase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;CoA-transferase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of CoA-transferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;CoA-transferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905920</classIRI>
<classLabel>positive regulation of CoA-transferase activity</classLabel>
<deletedAxiom>&apos;positive regulation of CoA-transferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;CoA-transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of CoA-transferase activity&apos; SubClassOf &apos;positive regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of CoA-transferase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;CoA-transferase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903231</classIRI>
<classLabel>mRNA base-pairing translational repressor activity</classLabel>
<deletedAxiom>&apos;mRNA base-pairing translational repressor activity&apos; SubClassOf &apos;mRNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;mRNA base-pairing translational repressor activity&apos; SubClassOf &apos;translation repressor activity&apos;</deletedAxiom>
<newAxiom>&apos;mRNA base-pairing translational repressor activity&apos; SubClassOf &apos;sequence-specific mRNA binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903281</classIRI>
<classLabel>positive regulation of calcium:sodium antiporter activity</classLabel>
<deletedAxiom>&apos;positive regulation of calcium:sodium antiporter activity&apos; SubClassOf &apos;positive regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium:sodium antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcium:sodium antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium:sodium antiporter activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium:sodium antiporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcium:sodium antiporter activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903284</classIRI>
<classLabel>positive regulation of glutathione peroxidase activity</classLabel>
<deletedAxiom>&apos;positive regulation of glutathione peroxidase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;glutathione peroxidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutathione peroxidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;glutathione peroxidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutathione peroxidase activity&apos; SubClassOf &apos;positive regulation of peroxidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of glutathione peroxidase activity&apos; SubClassOf &apos;regulation of glutathione peroxidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903258</classIRI>
<classLabel>sorbose import across plasma membrane</classLabel>
<deletedAxiom>&apos;sorbose import across plasma membrane&apos; SubClassOf &apos;hexose import across plasma membrane&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016889</classIRI>
<classLabel>DNA endonuclease activity, producing 3&apos;-phosphomonoesters</classLabel>
<newAxiom>&apos;DNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016888</classIRI>
<classLabel>DNA endonuclease activity, producing 5&apos;-phosphomonoesters</classLabel>
<newAxiom>&apos;DNA endonuclease activity, producing 5&apos;-phosphomonoesters&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903407</classIRI>
<classLabel>negative regulation of P-type sodium:potassium-exchanging transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of P-type sodium:potassium-exchanging transporter activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016894</classIRI>
<classLabel>endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3&apos;-phosphomonoesters</classLabel>
<deletedAxiom>&apos;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3&apos;-phosphomonoesters&apos; SubClassOf &apos;endonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016893</classIRI>
<classLabel>endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5&apos;-phosphomonoesters</classLabel>
<deletedAxiom>&apos;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5&apos;-phosphomonoesters&apos; SubClassOf &apos;endonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016892</classIRI>
<classLabel>RNA endonuclease activity, producing 3&apos;-phosphomonoesters</classLabel>
<newAxiom>&apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016891</classIRI>
<classLabel>RNA endonuclease activity, producing 5&apos;-phosphomonoesters</classLabel>
<newAxiom>&apos;RNA endonuclease activity, producing 5&apos;-phosphomonoesters&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016890</classIRI>
<classLabel>site-specific endodeoxyribonuclease activity, specific for altered base</classLabel>
<deletedAxiom>&apos;site-specific endodeoxyribonuclease activity, specific for altered base&apos; SubClassOf &apos;DNA endonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016797</classIRI>
<classLabel>exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3&apos;-phosphomonoesters</classLabel>
<deletedAxiom>&apos;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3&apos;-phosphomonoesters&apos; SubClassOf &apos;exonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016796</classIRI>
<classLabel>exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5&apos;-phosphomonoesters</classLabel>
<deletedAxiom>&apos;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5&apos;-phosphomonoesters&apos; SubClassOf &apos;exonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002229</classIRI>
<classLabel>defense response to oomycetes</classLabel>
<deletedAxiom>&apos;defense response to oomycetes&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to oomycetes&apos; SubClassOf &apos;defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002215</classIRI>
<classLabel>defense response to nematode</classLabel>
<deletedAxiom>&apos;defense response to nematode&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to nematode&apos; SubClassOf &apos;response to other organism&apos;</newAxiom>
<newAxiom>&apos;defense response to nematode&apos; SubClassOf &apos;defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002213</classIRI>
<classLabel>defense response to insect</classLabel>
<deletedAxiom>&apos;defense response to insect&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to insect&apos; SubClassOf &apos;defense response&apos;</newAxiom>
<newAxiom>&apos;defense response to insect&apos; SubClassOf &apos;response to other organism&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099108</classIRI>
<classLabel>potassium channel activator activity involved in G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;potassium channel activator activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;potassium channel activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;potassium channel activator activity involved in G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;potassium channel activator activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;potassium channel activator activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;ion channel regulator activity involved in G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099107</classIRI>
<classLabel>ion channel regulator activity involved in G protein-coupled receptor signaling pathway</classLabel>
<deletedAxiom>&apos;ion channel regulator activity involved in G protein-coupled receptor signaling pathway&apos; EquivalentTo &apos;ion channel regulator activity&apos; and (http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G protein-coupled receptor signaling pathway&apos;)</deletedAxiom>
<deletedAxiom>&apos;ion channel regulator activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf &apos;ion channel regulator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;ion channel regulator activity involved in G protein-coupled receptor signaling pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;G protein-coupled receptor signaling pathway&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090733</classIRI>
<classLabel>tenascin complex</classLabel>
<deletedAxiom>&apos;tenascin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;tenascin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099126</classIRI>
<classLabel>transforming growth factor beta complex</classLabel>
<deletedAxiom>&apos;transforming growth factor beta complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;transforming growth factor beta complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099074</classIRI>
<classLabel>mitochondrion to lysosome vesicle-mediated transport</classLabel>
<newAxiom>&apos;mitochondrion to lysosome vesicle-mediated transport&apos; SubClassOf &apos;mitochondrial transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099075</classIRI>
<classLabel>mitochondrion-derived vesicle mediated transport</classLabel>
<deletedAxiom>&apos;mitochondrion-derived vesicle mediated transport&apos; SubClassOf &apos;mitochondrial transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0099093</classIRI>
<classLabel>calcium export from the mitochondrion</classLabel>
<deletedAxiom>&apos;calcium export from the mitochondrion&apos; SubClassOf &apos;export from the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004738</classIRI>
<classLabel>pyruvate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004739</classIRI>
<classLabel>pyruvate dehydrogenase (acetyl-transferring) activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (acetyl-transferring) activity&apos; SubClassOf &apos;pyruvate dehydrogenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0002099</classIRI>
<classLabel>tRNA wobble guanine modification</classLabel>
<newAxiom>&apos;tRNA wobble guanine modification&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;queuosine biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051001</classIRI>
<classLabel>negative regulation of nitric-oxide synthase activity</classLabel>
<deletedAxiom>&apos;negative regulation of nitric-oxide synthase activity&apos; SubClassOf &apos;negative regulation of monooxygenase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of nitric-oxide synthase activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051000</classIRI>
<classLabel>positive regulation of nitric-oxide synthase activity</classLabel>
<deletedAxiom>&apos;positive regulation of nitric-oxide synthase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of nitric-oxide synthase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051086</classIRI>
<classLabel>chaperone mediated protein folding independent of cofactor</classLabel>
<deletedAxiom>&apos;chaperone mediated protein folding independent of cofactor&apos; SubClassOf &apos;chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;chaperone mediated protein folding independent of cofactor&apos; SubClassOf &apos;&apos;de novo&apos; post-translational protein folding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0051085</classIRI>
<classLabel>chaperone cofactor-dependent protein refolding</classLabel>
<deletedAxiom>&apos;chaperone cofactor-dependent protein refolding&apos; SubClassOf &apos;&apos;de novo&apos; post-translational protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;chaperone cofactor-dependent protein refolding&apos; SubClassOf &apos;chaperone-mediated protein folding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016604</classIRI>
<classLabel>nuclear body</classLabel>
<deletedAxiom>&apos;nuclear body&apos; SubClassOf &apos;cellular anatomical structure&apos;</deletedAxiom>
<newAxiom>&apos;nuclear body&apos; SubClassOf &apos;intracellular membraneless organelle&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004622</classIRI>
<classLabel>lysophospholipase activity</classLabel>
<deletedAxiom>&apos;lysophospholipase activity&apos; SubClassOf &apos;carboxylic ester hydrolase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;lysophospholipase activity&apos; SubClassOf &apos;phospholipase activity&apos;</deletedAxiom>
<newAxiom>&apos;lysophospholipase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120558</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903609</classIRI>
<classLabel>negative regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of inward rectifier potassium channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016607</classIRI>
<classLabel>nuclear speck</classLabel>
<deletedAxiom>&apos;nuclear speck&apos; SubClassOf &apos;nuclear body&apos;</deletedAxiom>
<newAxiom>&apos;nuclear speck&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140168</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903644</classIRI>
<classLabel>regulation of chaperone-mediated protein folding</classLabel>
<deletedAxiom>&apos;regulation of chaperone-mediated protein folding&apos; SubClassOf &apos;regulation of protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chaperone-mediated protein folding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of chaperone-mediated protein folding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;chaperone-mediated protein folding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903646</classIRI>
<classLabel>positive regulation of chaperone-mediated protein folding</classLabel>
<deletedAxiom>&apos;positive regulation of chaperone-mediated protein folding&apos; SubClassOf &apos;regulation of chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chaperone-mediated protein folding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;chaperone-mediated protein folding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chaperone-mediated protein folding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of chaperone-mediated protein folding&apos; SubClassOf &apos;positive regulation of protein folding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903645</classIRI>
<classLabel>negative regulation of chaperone-mediated protein folding</classLabel>
<deletedAxiom>&apos;negative regulation of chaperone-mediated protein folding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chaperone-mediated protein folding&apos; SubClassOf &apos;negative regulation of protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chaperone-mediated protein folding&apos; SubClassOf &apos;regulation of chaperone-mediated protein folding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of chaperone-mediated protein folding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;chaperone-mediated protein folding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016558</classIRI>
<classLabel>protein import into peroxisome matrix</classLabel>
<deletedAxiom>&apos;protein import into peroxisome matrix&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004578</classIRI>
<classLabel>chitobiosyldiphosphodolichol beta-mannosyltransferase activity</classLabel>
<newAxiom>&apos;chitobiosyldiphosphodolichol beta-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090551</classIRI>
<classLabel>response to manganese starvation</classLabel>
<deletedAxiom>&apos;response to manganese starvation&apos; SubClassOf &apos;response to starvation&apos;</deletedAxiom>
<newAxiom>&apos;response to manganese starvation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180055</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004518</classIRI>
<classLabel>nuclease activity</classLabel>
<deletedAxiom>&apos;nuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</deletedAxiom>
<newAxiom>&apos;nuclease activity&apos; SubClassOf &apos;catalytic activity, acting on a nucleic acid&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004522</classIRI>
<classLabel>ribonuclease A activity</classLabel>
<deletedAxiom>&apos;ribonuclease A activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease A activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
<newAxiom>&apos;ribonuclease A activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004527</classIRI>
<classLabel>exonuclease activity</classLabel>
<newAxiom>&apos;exonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903755</classIRI>
<classLabel>positive regulation of SUMO transferase activity</classLabel>
<deletedAxiom>&apos;positive regulation of SUMO transferase activity&apos; SubClassOf &apos;positive regulation of transferase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of SUMO transferase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;SUMO transferase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of SUMO transferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;SUMO transferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016538</classIRI>
<classLabel>cyclin-dependent protein serine/threonine kinase regulator activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein serine/threonine kinase regulator activity&apos; SubClassOf &apos;protein kinase regulator activity&apos;</deletedAxiom>
<newAxiom>&apos;cyclin-dependent protein serine/threonine kinase regulator activity&apos; SubClassOf &apos;cyclin-dependent protein kinase activating kinase regulator activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901019</classIRI>
<classLabel>regulation of calcium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of calcium ion transmembrane transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium ion transmembrane transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of monoatomic ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of calcium ion transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004458</classIRI>
<classLabel>D-lactate dehydrogenase (cytochrome) activity</classLabel>
<deletedAxiom>&apos;D-lactate dehydrogenase (cytochrome) activity&apos; SubClassOf &apos;lactate dehydrogenase activity&apos;</deletedAxiom>
<newAxiom>&apos;D-lactate dehydrogenase (cytochrome) activity&apos; SubClassOf &apos;D-2-hydroxy-acid dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004459</classIRI>
<classLabel>L-lactate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;L-lactate dehydrogenase activity&apos; SubClassOf &apos;lactate dehydrogenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;L-lactate dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;L-lactate dehydrogenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140171</newAxiom>
<newAxiom>&apos;L-lactate dehydrogenase activity&apos; SubClassOf &apos;L-2-hydroxycarboxylate dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901020</classIRI>
<classLabel>negative regulation of calcium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901021</classIRI>
<classLabel>positive regulation of calcium ion transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;positive regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium ion transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium ion transmembrane transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcium ion transmembrane transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcium ion transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004460</classIRI>
<classLabel>L-lactate dehydrogenase (cytochrome) activity</classLabel>
<deletedAxiom>&apos;L-lactate dehydrogenase (cytochrome) activity&apos; SubClassOf &apos;lactate dehydrogenase activity&apos;</deletedAxiom>
<newAxiom>&apos;L-lactate dehydrogenase (cytochrome) activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140171</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004483</classIRI>
<classLabel>mRNA (nucleoside-2&apos;-O-)-methyltransferase activity</classLabel>
<deletedAxiom>&apos;mRNA (nucleoside-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;mRNA methyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;mRNA (nucleoside-2&apos;-O-)-methyltransferase activity&apos; SubClassOf &apos;RNA methyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004486</classIRI>
<classLabel>methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity</classLabel>
<deletedAxiom>&apos;methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004487</classIRI>
<classLabel>methylenetetrahydrofolate dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;methylenetetrahydrofolate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<newAxiom>&apos;methylenetetrahydrofolate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004488</classIRI>
<classLabel>methylenetetrahydrofolate dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;methylenetetrahydrofolate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<newAxiom>&apos;methylenetetrahydrofolate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090374</classIRI>
<classLabel>oligopeptide export from mitochondrion</classLabel>
<deletedAxiom>&apos;oligopeptide export from mitochondrion&apos; SubClassOf &apos;export from the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2000013</classIRI>
<classLabel>regulation of arginine biosynthetic process via ornithine</classLabel>
<deletedAxiom>&apos;regulation of arginine biosynthetic process via ornithine&apos; SubClassOf &apos;regulation of ornithine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004358</classIRI>
<classLabel>glutamate N-acetyltransferase activity</classLabel>
<deletedAxiom>&apos;glutamate N-acetyltransferase activity&apos; SubClassOf &apos;N-acetyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;glutamate N-acetyltransferase activity&apos; SubClassOf &apos;L-amino-acid N-acetyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004377</classIRI>
<classLabel>GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity</classLabel>
<deletedAxiom>&apos;GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity&apos; SubClassOf &apos;glycolipid mannosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004378</classIRI>
<classLabel>GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity</classLabel>
<deletedAxiom>&apos;GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity&apos; SubClassOf &apos;glycolipid mannosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102704</classIRI>
<classLabel>GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity</classLabel>
<deletedAxiom>&apos;GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity&apos; SubClassOf &apos;glycolipid 1,6-alpha-mannosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity&apos; SubClassOf &apos;alpha-1,6-mannosyltransferase activity&apos;</newAxiom>
<newAxiom>&apos;GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901339</classIRI>
<classLabel>regulation of store-operated calcium channel activity</classLabel>
<deletedAxiom>&apos;regulation of store-operated calcium channel activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901341</classIRI>
<classLabel>positive regulation of store-operated calcium channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of store-operated calcium channel activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016257</classIRI>
<classLabel>N-glycan processing to secreted and cell-surface N-glycans</classLabel>
<deletedAxiom>&apos;N-glycan processing to secreted and cell-surface N-glycans&apos; SubClassOf &apos;N-glycan processing&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043867</classIRI>
<classLabel>7-cyano-7-deazaguanine tRNA-ribosyltransferase activity</classLabel>
<newAxiom>&apos;7-cyano-7-deazaguanine tRNA-ribosyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0016261</classIRI>
<classLabel>selenocysteine catabolic process</classLabel>
<deletedAxiom>&apos;selenocysteine catabolic process&apos; SubClassOf &apos;serine family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;selenocysteine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090144</classIRI>
<classLabel>mitochondrial nucleoid organization</classLabel>
<deletedAxiom>&apos;mitochondrial nucleoid organization&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;mitochondrial nucleoid organization&apos; EquivalentTo &apos;nucleoid organization&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;mitochondrion&apos;)</deletedAxiom>
<deletedAxiom>&apos;mitochondrial nucleoid organization&apos; SubClassOf &apos;nucleoid organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0090143</classIRI>
<classLabel>nucleoid organization</classLabel>
<deletedAxiom>&apos;nucleoid organization&apos; SubClassOf &apos;cellular component organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006839</classIRI>
<classLabel>mitochondrial transport</classLabel>
<deletedAxiom>&apos;mitochondrial transport&apos; SubClassOf &apos;transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial transport&apos; SubClassOf &apos;intracellular transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006850</classIRI>
<classLabel>mitochondrial pyruvate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial pyruvate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;mitochondrial pyruvate transmembrane transport&apos; SubClassOf &apos;import into the mitochondrion&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006851</classIRI>
<classLabel>mitochondrial calcium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial calcium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901385</classIRI>
<classLabel>regulation of voltage-gated calcium channel activity</classLabel>
<deletedAxiom>&apos;regulation of voltage-gated calcium channel activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901387</classIRI>
<classLabel>positive regulation of voltage-gated calcium channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of voltage-gated calcium channel activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004108</classIRI>
<classLabel>citrate (Si)-synthase activity</classLabel>
<deletedAxiom>&apos;citrate (Si)-synthase activity&apos; SubClassOf &apos;citrate synthase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004127</classIRI>
<classLabel>(d)CMP kinase activity</classLabel>
<deletedAxiom>&apos;(d)CMP kinase activity&apos; SubClassOf &apos;nucleobase-containing compound kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004129</classIRI>
<classLabel>cytochrome-c oxidase activity</classLabel>
<deletedAxiom>&apos;cytochrome-c oxidase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on a heme group of donors&apos;</deletedAxiom>
<newAxiom>&apos;cytochrome-c oxidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxidoreductase activity, acting on a heme group of donors&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043771</classIRI>
<classLabel>cytidine kinase activity</classLabel>
<deletedAxiom>&apos;cytidine kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006735</classIRI>
<classLabel>NADH regeneration</classLabel>
<deletedAxiom>&apos;NADH regeneration&apos; SubClassOf &apos;NADH metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006734</classIRI>
<classLabel>NADH metabolic process</classLabel>
<deletedAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;nicotinamide nucleotide metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;NADH metabolic process&apos; SubClassOf &apos;purine nucleotide metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004001</classIRI>
<classLabel>adenosine kinase activity</classLabel>
<deletedAxiom>&apos;adenosine kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004033</classIRI>
<classLabel>aldo-keto reductase (NADPH) activity</classLabel>
<deletedAxiom>&apos;aldo-keto reductase (NADPH) activity&apos; SubClassOf &apos;alcohol dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0004057</classIRI>
<classLabel>arginyl-tRNA--protein transferase activity</classLabel>
<newAxiom>&apos;arginyl-tRNA--protein transferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006530</classIRI>
<classLabel>asparagine catabolic process</classLabel>
<deletedAxiom>&apos;asparagine catabolic process&apos; SubClassOf &apos;asparagine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;asparagine catabolic process&apos; SubClassOf &apos;glutamine family amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;asparagine catabolic process&apos; SubClassOf &apos;L-asparagine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018538</classIRI>
<classLabel>epoxide carboxylase activity</classLabel>
<deletedAxiom>&apos;epoxide carboxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006550</classIRI>
<classLabel>isoleucine catabolic process</classLabel>
<deletedAxiom>&apos;isoleucine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;isoleucine catabolic process&apos; SubClassOf &apos;aspartate family amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031526</classIRI>
<classLabel>brush border membrane</classLabel>
<newAxiom>&apos;brush border membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apical plasma membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006574</classIRI>
<classLabel>valine catabolic process</classLabel>
<deletedAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;valine catabolic process&apos; SubClassOf &apos;pyruvate family amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006593</classIRI>
<classLabel>ornithine catabolic process</classLabel>
<deletedAxiom>&apos;ornithine catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;ornithine catabolic process&apos; SubClassOf &apos;L-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018591</classIRI>
<classLabel>methyl tertiary butyl ether 3-monooxygenase activity</classLabel>
<deletedAxiom>&apos;methyl tertiary butyl ether 3-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
<deletedAxiom>&apos;methyl tertiary butyl ether 3-monooxygenase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018594</classIRI>
<classLabel>tert-butanol 2-monooxygenase activity</classLabel>
<deletedAxiom>&apos;tert-butanol 2-monooxygenase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;tert-butanol 2-monooxygenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031587</classIRI>
<classLabel>positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102354</classIRI>
<classLabel>11-cis-retinol dehydrogenase activity</classLabel>
<deletedAxiom>&apos;11-cis-retinol dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;11-cis-retinol dehydrogenase activity&apos; SubClassOf &apos;alcohol dehydrogenase (NADP+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0031585</classIRI>
<classLabel>regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043490</classIRI>
<classLabel>malate-aspartate shuttle</classLabel>
<deletedAxiom>&apos;malate-aspartate shuttle&apos; SubClassOf &apos;NADH metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0018421</classIRI>
<classLabel>UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity</classLabel>
<deletedAxiom>&apos;UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity&apos; SubClassOf &apos;phosphotransferase activity, for other substituted phosphate groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102237</classIRI>
<classLabel>ATP:farnesol kinase activity</classLabel>
<deletedAxiom>&apos;ATP:farnesol kinase activity&apos; SubClassOf &apos;prenol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102238</classIRI>
<classLabel>ATP:geraniol kinase activity</classLabel>
<deletedAxiom>&apos;ATP:geraniol kinase activity&apos; SubClassOf &apos;geraniol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102243</classIRI>
<classLabel>ATP:geranylgeraniol kinase activity</classLabel>
<deletedAxiom>&apos;ATP:geranylgeraniol kinase activity&apos; SubClassOf &apos;geranylgeraniol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0043395</classIRI>
<classLabel>heparan sulfate proteoglycan binding</classLabel>
<deletedAxiom>&apos;heparan sulfate proteoglycan binding&apos; SubClassOf &apos;sulfur compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901894</classIRI>
<classLabel>regulation of ATPase-coupled calcium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;regulation of ATPase-coupled calcium transmembrane transporter activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ATPase-coupled calcium transmembrane transporter activity&apos; SubClassOf &apos;regulation of monoatomic ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901896</classIRI>
<classLabel>positive regulation of ATPase-coupled calcium transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;positive regulation of ATPase-coupled calcium transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of ATPase-coupled calcium transmembrane transporter activity&apos; SubClassOf &apos;positive regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008946</classIRI>
<classLabel>oligonucleotidase activity</classLabel>
<deletedAxiom>&apos;oligonucleotidase activity&apos; SubClassOf &apos;nuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033902</classIRI>
<classLabel>rRNA endonuclease activity</classLabel>
<deletedAxiom>&apos;rRNA endonuclease activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;rRNA endonuclease activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
<newAxiom>&apos;rRNA endonuclease activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102198</classIRI>
<classLabel>L-idonate 5-dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;L-idonate 5-dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;L-idonate 5-dehydrogenase (NAD+) activity&apos; SubClassOf &apos;L-idonate 5-dehydrogenase [NAD(P)+] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008995</classIRI>
<classLabel>ribonuclease E activity</classLabel>
<deletedAxiom>&apos;ribonuclease E activity&apos; SubClassOf &apos;RNA nuclease activity&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease E activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 5&apos;-phosphomonoesters&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070926</classIRI>
<classLabel>regulation of ATP:ADP antiporter activity</classLabel>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;regulation of monoatomic anion transmembrane transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;regulation of nucleobase-containing compound transport&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;ATP:ADP antiporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; SubClassOf &apos;regulation of transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of ATP:ADP antiporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;ATP:ADP antiporter activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901919</classIRI>
<classLabel>positive regulation of exoribonuclease activity</classLabel>
<newAxiom>&apos;positive regulation of exoribonuclease activity&apos; SubClassOf &apos;positive regulation of hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901979</classIRI>
<classLabel>regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;inward rectifier potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of potassium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of inward rectifier potassium channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;inward rectifier potassium channel activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1901980</classIRI>
<classLabel>positive regulation of inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;inward rectifier potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;inward rectifier potassium channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of inward rectifier potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of inward rectifier potassium channel activity&apos; SubClassOf &apos;positive regulation of voltage-gated potassium channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008914</classIRI>
<classLabel>leucyl-tRNA--protein transferase activity</classLabel>
<newAxiom>&apos;leucyl-tRNA--protein transferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008842</classIRI>
<classLabel>diphosphate-purine nucleoside kinase activity</classLabel>
<deletedAxiom>&apos;diphosphate-purine nucleoside kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;diphosphate-purine nucleoside kinase activity&apos; SubClassOf &apos;nucleoside kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008847</classIRI>
<classLabel>Enterobacter ribonuclease activity</classLabel>
<deletedAxiom>&apos;Enterobacter ribonuclease activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;Enterobacter ribonuclease activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
<newAxiom>&apos;Enterobacter ribonuclease activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102091</classIRI>
<classLabel>phosphatidylinositol-5-phosphate phosphatase activity</classLabel>
<newAxiom>&apos;phosphatidylinositol-5-phosphate phosphatase activity&apos; SubClassOf &apos;phosphatidylinositol phosphate 5-phosphatase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008888</classIRI>
<classLabel>glycerol dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;glycerol dehydrogenase (NAD+) activity&apos; SubClassOf &apos;glycerol dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<newAxiom>&apos;glycerol dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006236</classIRI>
<classLabel>cytidine salvage</classLabel>
<deletedAxiom>&apos;cytidine salvage&apos; SubClassOf &apos;cytidine biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;cytidine salvage&apos; SubClassOf &apos;pyrimidine nucleoside salvage&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0102029</classIRI>
<classLabel>D-lactate dehydrogenase (quinone) activity</classLabel>
<deletedAxiom>&apos;D-lactate dehydrogenase (quinone) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;D-lactate dehydrogenase (quinone) activity&apos; SubClassOf &apos;D-2-hydroxyacid dehydrogenase (quinone) activity&apos;</newAxiom>
<newAxiom>&apos;D-lactate dehydrogenase (quinone) activity&apos; SubClassOf &apos;D-2-hydroxy-acid dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033862</classIRI>
<classLabel>UMP kinase activity</classLabel>
<deletedAxiom>&apos;UMP kinase activity&apos; SubClassOf &apos;UMP/dUMP kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033892</classIRI>
<classLabel>deoxyribonuclease (pyrimidine dimer) activity</classLabel>
<deletedAxiom>&apos;deoxyribonuclease (pyrimidine dimer) activity&apos; SubClassOf &apos;site-specific endodeoxyribonuclease activity, specific for altered base&apos;</deletedAxiom>
<newAxiom>&apos;deoxyribonuclease (pyrimidine dimer) activity&apos; SubClassOf &apos;DNA endonuclease activity&apos;</newAxiom>
<newAxiom>&apos;deoxyribonuclease (pyrimidine dimer) activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033899</classIRI>
<classLabel>ribonuclease U2 activity</classLabel>
<deletedAxiom>&apos;ribonuclease U2 activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease U2 activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
<newAxiom>&apos;ribonuclease U2 activity&apos; SubClassOf &apos;phosphorus-oxygen lyase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033897</classIRI>
<classLabel>ribonuclease T2 activity</classLabel>
<deletedAxiom>&apos;ribonuclease T2 activity&apos; SubClassOf &apos;RNA endonuclease activity, producing 3&apos;-phosphomonoesters&apos;</deletedAxiom>
<newAxiom>&apos;ribonuclease T2 activity&apos; SubClassOf &apos;RNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055108</classIRI>
<classLabel>Golgi to transport vesicle transport</classLabel>
<deletedAxiom>&apos;Golgi to transport vesicle transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0055107</classIRI>
<classLabel>Golgi to secretory granule transport</classLabel>
<deletedAxiom>&apos;Golgi to secretory granule transport&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000066 some &apos;cytoplasm&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008705</classIRI>
<classLabel>methionine synthase activity</classLabel>
<deletedAxiom>&apos;methionine synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;methionine biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;methionine synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;L-methionine salvage&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008720</classIRI>
<classLabel>D-lactate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;D-lactate dehydrogenase activity&apos; SubClassOf &apos;lactate dehydrogenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;D-lactate dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;D-lactate dehydrogenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140175</newAxiom>
<newAxiom>&apos;D-lactate dehydrogenase activity&apos; SubClassOf &apos;D-2-hydroxy-acid dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006127</classIRI>
<classLabel>glycerol-3-phosphate shuttle</classLabel>
<deletedAxiom>&apos;glycerol-3-phosphate shuttle&apos; SubClassOf &apos;NADH metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045741</classIRI>
<classLabel>positive regulation of epidermal growth factor-activated receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of epidermal growth factor-activated receptor activity&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006086</classIRI>
<classLabel>pyruvate decarboxylation to acetyl-CoA</classLabel>
<newAxiom>&apos;pyruvate decarboxylation to acetyl-CoA&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;dihydrolipoyl dehydrogenase (NADH) activity&apos;</newAxiom>
<newAxiom>&apos;pyruvate decarboxylation to acetyl-CoA&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;pyruvate dehydrogenase (acetyl-transferring) activity&apos;</newAxiom>
<newAxiom>&apos;pyruvate decarboxylation to acetyl-CoA&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;cellular respiration&apos;</newAxiom>
<newAxiom>&apos;pyruvate decarboxylation to acetyl-CoA&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;dihydrolipoyllysine-residue acetyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0006096</classIRI>
<classLabel>glycolytic process</classLabel>
<newAxiom>&apos;glycolytic process&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;aerobic respiration&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008616</classIRI>
<classLabel>queuosine biosynthetic process</classLabel>
<deletedAxiom>&apos;queuosine biosynthetic process&apos; SubClassOf &apos;ribonucleoside biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;queuosine biosynthetic process&apos; SubClassOf &apos;queuosine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;queuosine biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033556</classIRI>
<classLabel>dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity</classLabel>
<deletedAxiom>&apos;dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity&apos; SubClassOf &apos;glucosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0070577</classIRI>
<classLabel>lysine-acetylated histone binding</classLabel>
<deletedAxiom>&apos;lysine-acetylated histone binding&apos; SubClassOf &apos;acetylation-dependent protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;lysine-acetylated histone binding&apos; SubClassOf &apos;histone binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008414</classIRI>
<classLabel>CDP-alcohol phosphotransferase activity</classLabel>
<deletedAxiom>&apos;CDP-alcohol phosphotransferase activity&apos; SubClassOf &apos;transferase activity, transferring phosphorus-containing groups&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008418</classIRI>
<classLabel>protein-N-terminal asparagine amidohydrolase activity</classLabel>
<deletedAxiom>&apos;protein-N-terminal asparagine amidohydrolase activity&apos; SubClassOf &apos;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides&apos;</deletedAxiom>
<deletedAxiom>&apos;protein-N-terminal asparagine amidohydrolase activity&apos; SubClassOf &apos;catalytic activity, acting on a protein&apos;</deletedAxiom>
<newAxiom>&apos;protein-N-terminal asparagine amidohydrolase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0160260</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047956</classIRI>
<classLabel>glycerol dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;glycerol dehydrogenase (NADP+) activity&apos; SubClassOf &apos;glycerol dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<newAxiom>&apos;glycerol dehydrogenase (NADP+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047995</classIRI>
<classLabel>hydroxyphenylpyruvate reductase activity</classLabel>
<deletedAxiom>&apos;hydroxyphenylpyruvate reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;hydroxyphenylpyruvate reductase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140175</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008399</classIRI>
<classLabel>naphthalene hydroxylase activity</classLabel>
<deletedAxiom>&apos;naphthalene hydroxylase activity&apos; SubClassOf &apos;monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;naphthalene hydroxylase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033342</classIRI>
<classLabel>negative regulation of collagen binding</classLabel>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;collagen binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;collagen binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of collagen binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141153</classIRI>
<classLabel>glycerol-3-phosphate dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;glycerol-3-phosphate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;glycerol-3-phosphate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;glycerol-3-phosphate dehydrogenase [NAD(P)+] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0141152</classIRI>
<classLabel>glycerol-3-phosphate dehydrogenase (NAD+) activity</classLabel>
<deletedAxiom>&apos;glycerol-3-phosphate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;glycerol-3-phosphate dehydrogenase (NAD+) activity&apos; SubClassOf &apos;glycerol-3-phosphate dehydrogenase [NAD(P)+] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035927</classIRI>
<classLabel>RNA import into mitochondrion</classLabel>
<deletedAxiom>&apos;RNA import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
<newAxiom>&apos;RNA import into mitochondrion&apos; SubClassOf &apos;transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008251</classIRI>
<classLabel>tRNA-specific adenosine deaminase activity</classLabel>
<newAxiom>&apos;tRNA-specific adenosine deaminase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033214</classIRI>
<classLabel>siderophore-dependent iron import into cell</classLabel>
<deletedAxiom>&apos;siderophore-dependent iron import into cell&apos; SubClassOf &apos;iron import into cell&apos;</deletedAxiom>
<newAxiom>&apos;siderophore-dependent iron import into cell&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180060</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047874</classIRI>
<classLabel>dolichyldiphosphatase activity</classLabel>
<deletedAxiom>&apos;dolichyldiphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;dolichyldiphosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045252</classIRI>
<classLabel>oxoglutarate dehydrogenase complex</classLabel>
<newAxiom>&apos;oxoglutarate dehydrogenase complex&apos; SubClassOf &apos;transferase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045254</classIRI>
<classLabel>pyruvate dehydrogenase complex</classLabel>
<newAxiom>&apos;pyruvate dehydrogenase complex&apos; SubClassOf &apos;acetyltransferase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045275</classIRI>
<classLabel>respiratory chain complex III</classLabel>
<deletedAxiom>&apos;respiratory chain complex III&apos; SubClassOf &apos;oxidoreductase complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045277</classIRI>
<classLabel>respiratory chain complex IV</classLabel>
<deletedAxiom>&apos;respiratory chain complex IV&apos; SubClassOf &apos;oxidoreductase complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047809</classIRI>
<classLabel>D-2-hydroxy-acid dehydrogenase activity</classLabel>
<deletedAxiom>&apos;D-2-hydroxy-acid dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on CH-OH group of donors&apos;</deletedAxiom>
<newAxiom>&apos;D-2-hydroxy-acid dehydrogenase activity&apos; SubClassOf &apos;2-oxo-acid reductase activity&apos;</newAxiom>
<newAxiom>&apos;D-2-hydroxy-acid dehydrogenase activity&apos; SubClassOf &apos;lactate dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060700</classIRI>
<classLabel>regulation of ribonuclease activity</classLabel>
<deletedAxiom>&apos;regulation of ribonuclease activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of ribonuclease activity&apos; SubClassOf &apos;regulation of catalytic activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008137</classIRI>
<classLabel>NADH dehydrogenase (ubiquinone) activity</classLabel>
<deletedAxiom>&apos;NADH dehydrogenase (ubiquinone) activity&apos; SubClassOf &apos;NADH dehydrogenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;NADH dehydrogenase (ubiquinone) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;NADH dehydrogenase (ubiquinone) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor&apos;</newAxiom>
<newAxiom>&apos;NADH dehydrogenase (ubiquinone) activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;NADH dehydrogenase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047759</classIRI>
<classLabel>butanal dehydrogenase activity</classLabel>
<deletedAxiom>&apos;butanal dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;butanal dehydrogenase activity&apos; SubClassOf &apos;aldehyde dehydrogenase [NAD(P)+] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047791</classIRI>
<classLabel>cucurbitacin Delta23 reductase [NAD(P)H] activity</classLabel>
<deletedAxiom>&apos;cucurbitacin Delta23 reductase [NAD(P)H] activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045156</classIRI>
<classLabel>electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity</classLabel>
<deletedAxiom>&apos;electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity&apos; SubClassOf &apos;electron transfer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045157</classIRI>
<classLabel>electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity</classLabel>
<deletedAxiom>&apos;electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity&apos; SubClassOf &apos;electron transfer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045158</classIRI>
<classLabel>electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity</classLabel>
<deletedAxiom>&apos;electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity&apos; SubClassOf &apos;electron transfer activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033164</classIRI>
<classLabel>glycolipid 1,6-alpha-mannosyltransferase activity</classLabel>
<deletedAxiom>&apos;glycolipid 1,6-alpha-mannosyltransferase activity&apos; SubClassOf &apos;glycolipid mannosyltransferase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033166</classIRI>
<classLabel>hyaline layer</classLabel>
<deletedAxiom>&apos;hyaline layer&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;hyaline layer&apos; SubClassOf &apos;specialized extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033165</classIRI>
<classLabel>interphotoreceptor matrix</classLabel>
<deletedAxiom>&apos;interphotoreceptor matrix&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008106</classIRI>
<classLabel>alcohol dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;alcohol dehydrogenase (NADP+) activity&apos; SubClassOf &apos;aldo-keto reductase (NADPH) activity&apos;</deletedAxiom>
<newAxiom>&apos;alcohol dehydrogenase (NADP+) activity&apos; SubClassOf &apos;alcohol dehydrogenase [NAD(P)+] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0008121</classIRI>
<classLabel>ubiquinol-cytochrome-c reductase activity</classLabel>
<deletedAxiom>&apos;ubiquinol-cytochrome-c reductase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on diphenols and related substances as donors&apos;</deletedAxiom>
<newAxiom>&apos;ubiquinol-cytochrome-c reductase activity&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;oxidoreductase activity, acting on diphenols and related substances as donors&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035624</classIRI>
<classLabel>receptor transactivation</classLabel>
<deletedAxiom>&apos;receptor transactivation&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045016</classIRI>
<classLabel>mitochondrial magnesium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial magnesium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0033019</classIRI>
<classLabel>5-hydroxyvalerate dehydrogenase activity</classLabel>
<deletedAxiom>&apos;5-hydroxyvalerate dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045039</classIRI>
<classLabel>protein insertion into mitochondrial inner membrane</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial inner membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein targeting to mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045040</classIRI>
<classLabel>protein insertion into mitochondrial outer membrane</classLabel>
<deletedAxiom>&apos;protein insertion into mitochondrial outer membrane&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein targeting to mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0045041</classIRI>
<classLabel>protein import into mitochondrial intermembrane space</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;protein transmembrane import into intracellular organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein targeting to mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;protein import into mitochondrial intermembrane space&apos; SubClassOf &apos;protein transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060695</classIRI>
<classLabel>negative regulation of cholesterol transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of cholesterol transporter activity&apos; SubClassOf &apos;negative regulation of lipid transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cholesterol transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;cholesterol transfer activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of cholesterol transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;cholesterol transfer activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106429</classIRI>
<classLabel>11-cis-retinol dehydrogenase</classLabel>
<deletedAxiom>&apos;11-cis-retinol dehydrogenase&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;11-cis-retinol dehydrogenase&apos; SubClassOf &apos;alcohol dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060550</classIRI>
<classLabel>positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity</classLabel>
<deletedAxiom>&apos;positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;fructose 1,6-bisphosphate 1-phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity&apos; SubClassOf &apos;positive regulation of phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;fructose 1,6-bisphosphate 1-phosphatase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060558</classIRI>
<classLabel>regulation of calcidiol 1-monooxygenase activity</classLabel>
<deletedAxiom>&apos;regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcidiol 1-monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of calcidiol 1-monooxygenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;calcidiol 1-monooxygenase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060559</classIRI>
<classLabel>positive regulation of calcidiol 1-monooxygenase activity</classLabel>
<deletedAxiom>&apos;positive regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcidiol 1-monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcidiol 1-monooxygenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;calcidiol 1-monooxygenase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;regulation of calcidiol 1-monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060585</classIRI>
<classLabel>positive regulation of prostaglandin-endoperoxide synthase activity</classLabel>
<deletedAxiom>&apos;positive regulation of prostaglandin-endoperoxide synthase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of prostaglandin-endoperoxide synthase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;prostaglandin-endoperoxide synthase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106366</classIRI>
<classLabel>guanosine kinase activity</classLabel>
<deletedAxiom>&apos;guanosine kinase activity&apos; SubClassOf &apos;phosphotransferase activity, alcohol group as acceptor&apos;</deletedAxiom>
<deletedAxiom>&apos;guanosine kinase activity&apos; SubClassOf &apos;kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;guanosine kinase activity&apos; SubClassOf &apos;nucleoside kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106314</classIRI>
<classLabel>obsolete nitrite reductase NADPH activity</classLabel>
<newAxiom>&apos;obsolete nitrite reductase NADPH activity&apos; SubClassOf &apos;nitrite reductase [NAD(P)H] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106316</classIRI>
<classLabel>nitrite reductase NADH activity</classLabel>
<deletedAxiom>&apos;nitrite reductase NADH activity&apos; SubClassOf &apos;nitrite reductase activity&apos;</deletedAxiom>
<newAxiom>&apos;nitrite reductase NADH activity&apos; SubClassOf &apos;nitrite reductase [NAD(P)H] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106261</classIRI>
<classLabel>tRNA uridine(34) acetyltransferase activity</classLabel>
<newAxiom>&apos;tRNA uridine(34) acetyltransferase activity&apos; SubClassOf &apos;catalytic activity, acting on a tRNA&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106294</classIRI>
<classLabel>NADPH oxidase H202-forming activity</classLabel>
<deletedAxiom>&apos;NADPH oxidase H202-forming activity&apos; SubClassOf &apos;NAD(P)H oxidase H2O2-forming activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106293</classIRI>
<classLabel>NADH oxidase H202-forming activity</classLabel>
<deletedAxiom>&apos;NADH oxidase H202-forming activity&apos; SubClassOf &apos;NAD(P)H oxidase H2O2-forming activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098965</classIRI>
<classLabel>extracellular matrix of synaptic cleft</classLabel>
<deletedAxiom>&apos;extracellular matrix of synaptic cleft&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;extracellular matrix of synaptic cleft&apos; SubClassOf &apos;specialized extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098966</classIRI>
<classLabel>perisynaptic extracellular matrix</classLabel>
<deletedAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<deletedAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;synapse-associated extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;perisynaptic extracellular matrix&apos; SubClassOf &apos;synapse-associated extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060314</classIRI>
<classLabel>regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060316</classIRI>
<classLabel>positive regulation of ryanodine-sensitive calcium-release channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of ryanodine-sensitive calcium-release channel activity&apos; SubClassOf &apos;positive regulation of calcium ion transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035373</classIRI>
<classLabel>chondroitin sulfate proteoglycan binding</classLabel>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan binding&apos; SubClassOf &apos;glycosaminoglycan binding&apos;</deletedAxiom>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan binding&apos; SubClassOf &apos;sulfur compound binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035363</classIRI>
<classLabel>histone locus body</classLabel>
<deletedAxiom>&apos;histone locus body&apos; SubClassOf &apos;nuclear body&apos;</deletedAxiom>
<newAxiom>&apos;histone locus body&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140168</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060274</classIRI>
<classLabel>maintenance of stationary phase</classLabel>
<deletedAxiom>&apos;maintenance of stationary phase&apos; SubClassOf &apos;cellular homeostasis&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060275</classIRI>
<classLabel>maintenance of stationary phase in response to starvation</classLabel>
<deletedAxiom>&apos;maintenance of stationary phase in response to starvation&apos; SubClassOf &apos;response to starvation&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of stationary phase in response to starvation&apos; SubClassOf &apos;maintenance of stationary phase&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060276</classIRI>
<classLabel>maintenance of stationary phase in response to toxin</classLabel>
<deletedAxiom>&apos;maintenance of stationary phase in response to toxin&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;response to toxic substance&apos;</deletedAxiom>
<deletedAxiom>&apos;maintenance of stationary phase in response to toxin&apos; SubClassOf &apos;maintenance of stationary phase&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905097</classIRI>
<classLabel>regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of GTPase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of guanyl-nucleotide exchange factor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;guanyl-nucleotide exchange factor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905098</classIRI>
<classLabel>negative regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;negative regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of GTPase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905099</classIRI>
<classLabel>positive regulation of guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;guanyl-nucleotide exchange factor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;positive regulation of GTP binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050832</classIRI>
<classLabel>defense response to fungus</classLabel>
<deletedAxiom>&apos;defense response to fungus&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to fungus&apos; SubClassOf &apos;defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0106073</classIRI>
<classLabel>dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity</classLabel>
<deletedAxiom>&apos;dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity&apos; SubClassOf &apos;glucosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity&apos; SubClassOf &apos;dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060130</classIRI>
<classLabel>thyroid-stimulating hormone-secreting cell development</classLabel>
<deletedAxiom>&apos;thyroid-stimulating hormone-secreting cell development&apos; SubClassOf &apos;neuron development&apos;</deletedAxiom>
<newAxiom>&apos;thyroid-stimulating hormone-secreting cell development&apos; SubClassOf &apos;forebrain neuron development&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060129</classIRI>
<classLabel>thyroid-stimulating hormone-secreting cell differentiation</classLabel>
<newAxiom>&apos;thyroid-stimulating hormone-secreting cell differentiation&apos; SubClassOf &apos;forebrain neuron differentiation&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905151</classIRI>
<classLabel>negative regulation of voltage-gated sodium channel activity</classLabel>
<deletedAxiom>&apos;negative regulation of voltage-gated sodium channel activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of voltage-gated sodium channel activity&apos; SubClassOf &apos;negative regulation of cation channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of voltage-gated sodium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;voltage-gated sodium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of voltage-gated sodium channel activity&apos; SubClassOf &apos;regulation of voltage-gated sodium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of voltage-gated sodium channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;voltage-gated sodium channel activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047101</classIRI>
<classLabel>branched-chain alpha-keto acid dehydrogenase activity</classLabel>
<deletedAxiom>&apos;branched-chain alpha-keto acid dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047104</classIRI>
<classLabel>hexadecanal dehydrogenase (acylating) activity</classLabel>
<deletedAxiom>&apos;hexadecanal dehydrogenase (acylating) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;hexadecanal dehydrogenase (acylating) activity&apos; SubClassOf &apos;long-chain fatty aldehyde dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0060102</classIRI>
<classLabel>cuticular extracellular matrix</classLabel>
<deletedAxiom>&apos;cuticular extracellular matrix&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098643</classIRI>
<classLabel>banded collagen fibril</classLabel>
<deletedAxiom>&apos;banded collagen fibril&apos; SubClassOf &apos;supramolecular fiber&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098644</classIRI>
<classLabel>complex of collagen trimers</classLabel>
<deletedAxiom>&apos;complex of collagen trimers&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;complex of collagen trimers&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098645</classIRI>
<classLabel>collagen network</classLabel>
<deletedAxiom>&apos;collagen network&apos; SubClassOf &apos;supramolecular polymer&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0098646</classIRI>
<classLabel>interstitial hexagonal collagen network</classLabel>
<newAxiom>&apos;interstitial hexagonal collagen network&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;interstitial matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047042</classIRI>
<classLabel>androsterone dehydrogenase (B-specific) activity</classLabel>
<deletedAxiom>&apos;androsterone dehydrogenase (B-specific) activity&apos; SubClassOf &apos;androsterone dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0035064</classIRI>
<classLabel>methylated histone binding</classLabel>
<deletedAxiom>&apos;methylated histone binding&apos; SubClassOf &apos;methylation-dependent protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;methylated histone binding&apos; SubClassOf &apos;histone binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0001758</classIRI>
<classLabel>retinal dehydrogenase activity</classLabel>
<deletedAxiom>&apos;retinal dehydrogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;retinal dehydrogenase activity&apos; SubClassOf &apos;aldehyde dehydrogenase (NAD+) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905118</classIRI>
<classLabel>positive regulation of ribonucleoside-diphosphate reductase activity</classLabel>
<deletedAxiom>&apos;positive regulation of ribonucleoside-diphosphate reductase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ribonucleoside-diphosphate reductase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ribonucleoside-diphosphate reductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ribonucleoside-diphosphate reductase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;ribonucleoside-diphosphate reductase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905123</classIRI>
<classLabel>regulation of glucosylceramidase activity</classLabel>
<deletedAxiom>&apos;regulation of glucosylceramidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;glucosylceramidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of glucosylceramidase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;glucosylceramidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of glucosylceramidase activity&apos; SubClassOf &apos;regulation of hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047005</classIRI>
<classLabel>16-alpha-hydroxysteroid dehydrogenase [NAD(P)+] activity</classLabel>
<deletedAxiom>&apos;16-alpha-hydroxysteroid dehydrogenase [NAD(P)+] activity&apos; SubClassOf &apos;steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050654</classIRI>
<classLabel>chondroitin sulfate proteoglycan metabolic process</classLabel>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan metabolic process&apos; SubClassOf &apos;glycosaminoglycan metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0047026</classIRI>
<classLabel>androsterone dehydrogenase (A-specific) activity</classLabel>
<deletedAxiom>&apos;androsterone dehydrogenase (A-specific) activity&apos; SubClassOf &apos;androsterone dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050650</classIRI>
<classLabel>chondroitin sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;glycosaminoglycan biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050578</classIRI>
<classLabel>(R)-2-hydroxyacid dehydrogenase activity</classLabel>
<newAxiom>&apos;(R)-2-hydroxyacid dehydrogenase activity&apos; SubClassOf &apos;2-oxo-acid reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905215</classIRI>
<classLabel>negative regulation of RNA binding</classLabel>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;RNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of RNA binding&apos; SubClassOf &apos;negative regulation of binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050450</classIRI>
<classLabel>citrate (Re)-synthase activity</classLabel>
<deletedAxiom>&apos;citrate (Re)-synthase activity&apos; SubClassOf &apos;citrate synthase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905408</classIRI>
<classLabel>negative regulation of creatine transmembrane transporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;creatine transmembrane transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;creatine transmembrane transporter activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;negative regulation of transporter activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of creatine transmembrane transporter activity&apos; SubClassOf &apos;regulation of transmembrane transporter activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050380</classIRI>
<classLabel>undecaprenyl-diphosphatase activity</classLabel>
<deletedAxiom>&apos;undecaprenyl-diphosphatase activity&apos; SubClassOf &apos;pyrophosphatase activity&apos;</deletedAxiom>
<newAxiom>&apos;undecaprenyl-diphosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120556</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905493</classIRI>
<classLabel>regulation of G-quadruplex DNA binding</classLabel>
<deletedAxiom>&apos;regulation of G-quadruplex DNA binding&apos; SubClassOf &apos;regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of G-quadruplex DNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;G-quadruplex DNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of G-quadruplex DNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;G-quadruplex DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0003906</classIRI>
<classLabel>DNA-(apurinic or apyrimidinic site) endonuclease activity</classLabel>
<deletedAxiom>&apos;DNA-(apurinic or apyrimidinic site) endonuclease activity&apos; SubClassOf &apos;catalytic activity, acting on DNA&apos;</deletedAxiom>
<newAxiom>&apos;DNA-(apurinic or apyrimidinic site) endonuclease activity&apos; SubClassOf &apos;DNA endonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052925</classIRI>
<classLabel>dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity</classLabel>
<newAxiom>&apos;dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052926</classIRI>
<classLabel>dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity</classLabel>
<newAxiom>&apos;dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052918</classIRI>
<classLabel>dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity</classLabel>
<newAxiom>&apos;dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052917</classIRI>
<classLabel>dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase</classLabel>
<deletedAxiom>&apos;dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase&apos; SubClassOf &apos;alpha-1,6-mannosyltransferase activity&apos;</deletedAxiom>
<newAxiom>&apos;dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0120562</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052873</classIRI>
<classLabel>FMN reductase (NADPH) activity</classLabel>
<deletedAxiom>&apos;FMN reductase (NADPH) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;FMN reductase (NADPH) activity&apos; SubClassOf &apos;FMN reductase [NAD(P)H] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052874</classIRI>
<classLabel>FMN reductase (NADH) activity</classLabel>
<deletedAxiom>&apos;FMN reductase (NADH) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;FMN reductase (NADH) activity&apos; SubClassOf &apos;FMN reductase [NAD(P)H] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050243</classIRI>
<classLabel>pyruvate dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;pyruvate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;pyruvate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
<newAxiom>&apos;pyruvate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905596</classIRI>
<classLabel>negative regulation of low-density lipoprotein particle receptor binding</classLabel>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein particle receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;low-density lipoprotein particle receptor binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein particle receptor binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;low-density lipoprotein particle receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein particle receptor binding&apos; SubClassOf &apos;negative regulation of receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905599</classIRI>
<classLabel>positive regulation of low-density lipoprotein receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;positive regulation of molecular function&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;low-density lipoprotein particle receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;low-density lipoprotein particle receptor activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905597</classIRI>
<classLabel>positive regulation of low-density lipoprotein particle receptor binding</classLabel>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein particle receptor binding&apos; SubClassOf &apos;positive regulation of receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein particle receptor binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;low-density lipoprotein particle receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of low-density lipoprotein particle receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;low-density lipoprotein particle receptor binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905598</classIRI>
<classLabel>negative regulation of low-density lipoprotein receptor activity</classLabel>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;negative regulation of receptor-mediated endocytosis&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;low-density lipoprotein particle receptor activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;low-density lipoprotein particle receptor activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of low-density lipoprotein receptor activity&apos; SubClassOf &apos;negative regulation of molecular function&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015859</classIRI>
<classLabel>intracellular nucleoside transport</classLabel>
<deletedAxiom>&apos;intracellular nucleoside transport&apos; EquivalentTo &apos;nucleoside transport&apos; and (http://purl.obolibrary.org/obo/BFO_0000066 some &apos;intracellular anatomical structure&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905612</classIRI>
<classLabel>positive regulation of mRNA cap binding</classLabel>
<deletedAxiom>&apos;positive regulation of mRNA cap binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;mRNA cap binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mRNA cap binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;mRNA cap binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of mRNA cap binding&apos; SubClassOf &apos;positive regulation of mRNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052770</classIRI>
<classLabel>coenzyme F390-A hydrolase activity</classLabel>
<deletedAxiom>&apos;coenzyme F390-A hydrolase activity&apos; SubClassOf &apos;hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052771</classIRI>
<classLabel>coenzyme F390-G hydrolase activity</classLabel>
<deletedAxiom>&apos;coenzyme F390-G hydrolase activity&apos; SubClassOf &apos;hydrolase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903007</classIRI>
<classLabel>positive regulation of Lys63-specific deubiquitinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of Lys63-specific deubiquitinase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;K63-linked deubiquitinase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Lys63-specific deubiquitinase activity&apos; SubClassOf &apos;positive regulation of protein K63-linked deubiquitination&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Lys63-specific deubiquitinase activity&apos; SubClassOf &apos;positive regulation of peptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of Lys63-specific deubiquitinase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;K63-linked deubiquitinase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050164</classIRI>
<classLabel>oxoglutarate dehydrogenase (NADP+) activity</classLabel>
<deletedAxiom>&apos;oxoglutarate dehydrogenase (NADP+) activity&apos; SubClassOf &apos;oxoglutarate dehydrogenase [NAD(P)+] activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1905636</classIRI>
<classLabel>positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding</classLabel>
<deletedAxiom>&apos;positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;regulation of RNA polymerase II regulatory region sequence-specific DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA polymerase II transcription regulatory region sequence-specific DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding&apos; SubClassOf &apos;positive regulation of transcription regulatory region DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA polymerase II transcription regulatory region sequence-specific DNA binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0050136</classIRI>
<classLabel>NADH:ubiquinone reductase (non-electrogenic) activity</classLabel>
<deletedAxiom>&apos;NADH:ubiquinone reductase (non-electrogenic) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;NADH:ubiquinone reductase (non-electrogenic) activity&apos; SubClassOf &apos;NAD(P)H dehydrogenase (quinone) activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903033</classIRI>
<classLabel>positive regulation of microtubule plus-end binding</classLabel>
<deletedAxiom>&apos;positive regulation of microtubule plus-end binding&apos; SubClassOf &apos;positive regulation of microtubule binding&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of microtubule plus-end binding&apos; SubClassOf &apos;positive regulation of protein binding&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1903016</classIRI>
<classLabel>negative regulation of exo-alpha-sialidase activity</classLabel>
<deletedAxiom>&apos;negative regulation of exo-alpha-sialidase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;exo-alpha-sialidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of exo-alpha-sialidase activity&apos; SubClassOf &apos;negative regulation of hydrolase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of exo-alpha-sialidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;exo-alpha-sialidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990420</classIRI>
<classLabel>establishment of septation initiation network asymmetry</classLabel>
<deletedAxiom>&apos;establishment of septation initiation network asymmetry&apos; SubClassOf &apos;septation initiation signaling&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990464</classIRI>
<classLabel>D-2-hydroxyacid dehydrogenase (quinone) activity</classLabel>
<newAxiom>&apos;D-2-hydroxyacid dehydrogenase (quinone) activity&apos; SubClassOf &apos;2-oxo-acid reductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052690</classIRI>
<classLabel>trichloro-p-hydroquinone reductive dehalogenase activity</classLabel>
<deletedAxiom>&apos;trichloro-p-hydroquinone reductive dehalogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on a sulfur group of donors&apos;</deletedAxiom>
<deletedAxiom>&apos;trichloro-p-hydroquinone reductive dehalogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on other nitrogenous compounds as donors&apos;</deletedAxiom>
<newAxiom>&apos;trichloro-p-hydroquinone reductive dehalogenase activity&apos; SubClassOf &apos;oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0062023</classIRI>
<classLabel>collagen-containing extracellular matrix</classLabel>
<deletedAxiom>&apos;collagen-containing extracellular matrix&apos; SubClassOf &apos;extracellular matrix&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052668</classIRI>
<classLabel>CTP:farnesol kinase activity</classLabel>
<deletedAxiom>&apos;CTP:farnesol kinase activity&apos; SubClassOf &apos;prenol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052671</classIRI>
<classLabel>geranylgeraniol kinase activity</classLabel>
<deletedAxiom>&apos;geranylgeraniol kinase activity&apos; SubClassOf &apos;prenol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052670</classIRI>
<classLabel>geraniol kinase activity</classLabel>
<deletedAxiom>&apos;geraniol kinase activity&apos; SubClassOf &apos;prenol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0052672</classIRI>
<classLabel>CTP:geranylgeraniol kinase activity</classLabel>
<deletedAxiom>&apos;CTP:geranylgeraniol kinase activity&apos; SubClassOf &apos;geranylgeraniol kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904434</classIRI>
<classLabel>positive regulation of ferrous iron binding</classLabel>
<deletedAxiom>&apos;positive regulation of ferrous iron binding&apos; SubClassOf &apos;positive regulation of binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ferrous iron binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;ferrous iron binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of ferrous iron binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;ferrous iron binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904437</classIRI>
<classLabel>positive regulation of transferrin receptor binding</classLabel>
<deletedAxiom>&apos;positive regulation of transferrin receptor binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;transferrin receptor binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transferrin receptor binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;transferrin receptor binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of transferrin receptor binding&apos; SubClassOf &apos;positive regulation of receptor binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990554</classIRI>
<classLabel>mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 3&apos;-phospho-5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990553</classIRI>
<classLabel>mitochondrial 5&apos;-adenylyl sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 5&apos;-adenylyl sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990551</classIRI>
<classLabel>mitochondrial 2-oxoadipate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial 2-oxoadipate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990550</classIRI>
<classLabel>mitochondrial alpha-ketoglutarate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial alpha-ketoglutarate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990549</classIRI>
<classLabel>mitochondrial NAD transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial NAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990548</classIRI>
<classLabel>mitochondrial FAD transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial FAD transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990547</classIRI>
<classLabel>mitochondrial phosphate ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial phosphate ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990546</classIRI>
<classLabel>mitochondrial tricarboxylic acid transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial tricarboxylic acid transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990545</classIRI>
<classLabel>mitochondrial thiamine pyrophosphate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial thiamine pyrophosphate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990544</classIRI>
<classLabel>mitochondrial ATP transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial ATP transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990543</classIRI>
<classLabel>mitochondrial S-adenosyl-L-methionine transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial S-adenosyl-L-methionine transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990540</classIRI>
<classLabel>mitochondrial manganese ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial manganese ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990559</classIRI>
<classLabel>mitochondrial coenzyme A transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial coenzyme A transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990558</classIRI>
<classLabel>mitochondrial malonate(1-) transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial malonate(1-) transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990557</classIRI>
<classLabel>mitochondrial sulfate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial sulfate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990556</classIRI>
<classLabel>mitochondrial isopropylmalate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial isopropylmalate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990555</classIRI>
<classLabel>mitochondrial oxaloacetate transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial oxaloacetate transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990519</classIRI>
<classLabel>pyrimidine nucleotide import into mitochondrion</classLabel>
<deletedAxiom>&apos;pyrimidine nucleotide import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015666</classIRI>
<classLabel>restriction endodeoxyribonuclease activity</classLabel>
<newAxiom>&apos;restriction endodeoxyribonuclease activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904616</classIRI>
<classLabel>regulation of actin binding</classLabel>
<deletedAxiom>&apos;regulation of actin binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of actin binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;actin binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of actin binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;actin binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904526</classIRI>
<classLabel>regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;microtubule binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of microtubule binding&apos; SubClassOf &apos;regulation of protein binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904527</classIRI>
<classLabel>negative regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;microtubule binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf &apos;negative regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of microtubule binding&apos; SubClassOf &apos;regulation of microtubule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904528</classIRI>
<classLabel>positive regulation of microtubule binding</classLabel>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf &apos;positive regulation of protein binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;microtubule binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;microtubule binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of microtubule binding&apos; SubClassOf &apos;regulation of microtubule binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904530</classIRI>
<classLabel>negative regulation of actin filament binding</classLabel>
<deletedAxiom>&apos;negative regulation of actin filament binding&apos; SubClassOf &apos;regulation of actin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904531</classIRI>
<classLabel>positive regulation of actin filament binding</classLabel>
<deletedAxiom>&apos;positive regulation of actin filament binding&apos; SubClassOf &apos;regulation of actin binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990616</classIRI>
<classLabel>magnesium ion export from mitochondrion</classLabel>
<deletedAxiom>&apos;magnesium ion export from mitochondrion&apos; SubClassOf &apos;export from the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990641</classIRI>
<classLabel>response to iron ion starvation</classLabel>
<deletedAxiom>&apos;response to iron ion starvation&apos; SubClassOf &apos;response to starvation&apos;</deletedAxiom>
<newAxiom>&apos;response to iron ion starvation&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0180055</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904684</classIRI>
<classLabel>negative regulation of metalloendopeptidase activity</classLabel>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity&apos; SubClassOf &apos;negative regulation of endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;metalloendopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity&apos; SubClassOf &apos;negative regulation of metallopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity&apos; SubClassOf &apos;regulation of metalloendopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of metalloendopeptidase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;metalloendopeptidase activity&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902079</classIRI>
<classLabel>D-valine catabolic process</classLabel>
<deletedAxiom>&apos;D-valine catabolic process&apos; SubClassOf &apos;valine catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;D-valine catabolic process&apos; SubClassOf &apos;branched-chain amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904743</classIRI>
<classLabel>negative regulation of telomeric DNA binding</classLabel>
<deletedAxiom>&apos;negative regulation of telomeric DNA binding&apos; SubClassOf &apos;negative regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of telomeric DNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;telomeric DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of telomeric DNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;telomeric DNA binding&apos;)</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904744</classIRI>
<classLabel>positive regulation of telomeric DNA binding</classLabel>
<deletedAxiom>&apos;positive regulation of telomeric DNA binding&apos; SubClassOf &apos;positive regulation of DNA binding&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of telomeric DNA binding&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;telomeric DNA binding&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of telomeric DNA binding&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;telomeric DNA binding&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904783</classIRI>
<classLabel>positive regulation of NMDA glutamate receptor activity</classLabel>
<deletedAxiom>&apos;positive regulation of NMDA glutamate receptor activity&apos; SubClassOf &apos;positive regulation of signaling receptor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005903</classIRI>
<classLabel>brush border</classLabel>
<newAxiom>&apos;brush border&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;apical part of cell&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005960</classIRI>
<classLabel>glycine cleavage complex</classLabel>
<newAxiom>&apos;glycine cleavage complex&apos; SubClassOf &apos;transferase complex&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030937</classIRI>
<classLabel>collagen type XVII trimer</classLabel>
<deletedAxiom>&apos;collagen type XVII trimer&apos; SubClassOf &apos;hemidesmosome associated protein complex&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030938</classIRI>
<classLabel>collagen type XVIII trimer</classLabel>
<deletedAxiom>&apos;collagen type XVIII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;basement membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen type XVIII trimer&apos; SubClassOf &apos;collagen trimer&apos;</deletedAxiom>
<newAxiom>&apos;collagen type XVIII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140156</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904960</classIRI>
<classLabel>positive regulation of cytochrome-c oxidase activity</classLabel>
<deletedAxiom>&apos;positive regulation of cytochrome-c oxidase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904947</classIRI>
<classLabel>folate import into mitochondrion</classLabel>
<deletedAxiom>&apos;folate import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1904959</classIRI>
<classLabel>regulation of cytochrome-c oxidase activity</classLabel>
<deletedAxiom>&apos;regulation of cytochrome-c oxidase activity&apos; SubClassOf &apos;regulation of oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042850</classIRI>
<classLabel>L-sorbose catabolic process</classLabel>
<deletedAxiom>&apos;L-sorbose catabolic process&apos; SubClassOf &apos;sorbose catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-sorbose catabolic process&apos; SubClassOf &apos;hexose catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001106</classIRI>
<classLabel>regulation of Rho guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;regulation of Rho guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;regulation of guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_2001108</classIRI>
<classLabel>positive regulation of Rho guanyl-nucleotide exchange factor activity</classLabel>
<deletedAxiom>&apos;positive regulation of Rho guanyl-nucleotide exchange factor activity&apos; SubClassOf &apos;positive regulation of guanyl-nucleotide exchange factor activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042847</classIRI>
<classLabel>sorbose biosynthetic process</classLabel>
<deletedAxiom>&apos;sorbose biosynthetic process&apos; SubClassOf &apos;sorbose metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;sorbose biosynthetic process&apos; SubClassOf &apos;hexose biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042849</classIRI>
<classLabel>L-sorbose biosynthetic process</classLabel>
<deletedAxiom>&apos;L-sorbose biosynthetic process&apos; SubClassOf &apos;sorbose biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-sorbose biosynthetic process&apos; SubClassOf &apos;hexose biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042848</classIRI>
<classLabel>sorbose catabolic process</classLabel>
<deletedAxiom>&apos;sorbose catabolic process&apos; SubClassOf &apos;sorbose metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;sorbose catabolic process&apos; SubClassOf &apos;hexose catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902261</classIRI>
<classLabel>positive regulation of delayed rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;positive regulation of delayed rectifier potassium channel activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;delayed rectifier potassium channel activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of delayed rectifier potassium channel activity&apos; SubClassOf &apos;regulation of delayed rectifier potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of delayed rectifier potassium channel activity&apos; SubClassOf &apos;positive regulation of voltage-gated potassium channel activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of delayed rectifier potassium channel activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;delayed rectifier potassium channel activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902283</classIRI>
<classLabel>negative regulation of primary amine oxidase activity</classLabel>
<deletedAxiom>&apos;negative regulation of primary amine oxidase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;primary methylamine oxidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of primary amine oxidase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;primary methylamine oxidase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of primary amine oxidase activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902380</classIRI>
<classLabel>positive regulation of endoribonuclease activity</classLabel>
<deletedAxiom>&apos;positive regulation of endoribonuclease activity&apos; SubClassOf &apos;positive regulation of nuclease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of endoribonuclease activity&apos; SubClassOf &apos;regulation of endoribonuclease activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of endoribonuclease activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA endonuclease activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of endoribonuclease activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;RNA endonuclease activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042742</classIRI>
<classLabel>defense response to bacterium</classLabel>
<deletedAxiom>&apos;defense response to bacterium&apos; SubClassOf &apos;defense response to other organism&apos;</deletedAxiom>
<newAxiom>&apos;defense response to bacterium&apos; SubClassOf &apos;defense response&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990972</classIRI>
<classLabel>multimerin complex</classLabel>
<deletedAxiom>&apos;multimerin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;multimerin complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1990971</classIRI>
<classLabel>EMILIN complex</classLabel>
<deletedAxiom>&apos;EMILIN complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;EMILIN complex&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042602</classIRI>
<classLabel>riboflavin reductase (NADPH) activity</classLabel>
<deletedAxiom>&apos;riboflavin reductase (NADPH) activity&apos; SubClassOf &apos;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor&apos;</deletedAxiom>
<newAxiom>&apos;riboflavin reductase (NADPH) activity&apos; SubClassOf &apos;riboflavin reductase [NAD(P)H] activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015012</classIRI>
<classLabel>heparan sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;heparan sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;sulfur compound biosynthetic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015030</classIRI>
<classLabel>Cajal body</classLabel>
<deletedAxiom>&apos;Cajal body&apos; SubClassOf &apos;nuclear body&apos;</deletedAxiom>
<newAxiom>&apos;Cajal body&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140168</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0015048</classIRI>
<classLabel>phthalate dioxygenase reductase activity</classLabel>
<deletedAxiom>&apos;phthalate dioxygenase reductase activity&apos; SubClassOf &apos;oxidoreductase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030668</classIRI>
<classLabel>merozoite dense granule membrane</classLabel>
<deletedAxiom>&apos;merozoite dense granule membrane&apos; SubClassOf &apos;cytoplasmic vesicle membrane&apos;</deletedAxiom>
<deletedAxiom>&apos;merozoite dense granule membrane&apos; SubClassOf &apos;bounding membrane of organelle&apos;</deletedAxiom>
<newAxiom>&apos;merozoite dense granule membrane&apos; SubClassOf &apos;secretory granule membrane&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005614</classIRI>
<classLabel>interstitial matrix</classLabel>
<deletedAxiom>&apos;interstitial matrix&apos; SubClassOf &apos;collagen-containing extracellular matrix&apos;</deletedAxiom>
<newAxiom>&apos;interstitial matrix&apos; SubClassOf &apos;extracellular matrix&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005582</classIRI>
<classLabel>collagen type XV trimer</classLabel>
<deletedAxiom>&apos;collagen type XV trimer&apos; SubClassOf &apos;collagen trimer&apos;</deletedAxiom>
<deletedAxiom>&apos;collagen type XV trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;basement membrane&apos;</deletedAxiom>
<newAxiom>&apos;collagen type XV trimer&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140156</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005589</classIRI>
<classLabel>collagen type VI trimer</classLabel>
<deletedAxiom>&apos;collagen type VI trimer&apos; SubClassOf &apos;collagen trimer&apos;</deletedAxiom>
<newAxiom>&apos;collagen type VI trimer&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140158</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005590</classIRI>
<classLabel>collagen type VII trimer</classLabel>
<deletedAxiom>&apos;collagen type VII trimer&apos; SubClassOf &apos;collagen trimer&apos;</deletedAxiom>
<newAxiom>&apos;collagen type VII trimer&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140158</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0005593</classIRI>
<classLabel>FACIT collagen trimer</classLabel>
<newAxiom>&apos;FACIT collagen trimer&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some http://purl.obolibrary.org/obo/GO_0140153</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140917</classIRI>
<classLabel>zinc ion import into mitochondrion</classLabel>
<deletedAxiom>&apos;zinc ion import into mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900128</classIRI>
<classLabel>regulation of G-protein activated inward rectifier potassium channel activity</classLabel>
<deletedAxiom>&apos;regulation of G-protein activated inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of inward rectifier potassium channel activity&apos;</deletedAxiom>
<newAxiom>&apos;regulation of G-protein activated inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of potassium ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;regulation of G-protein activated inward rectifier potassium channel activity&apos; SubClassOf &apos;regulation of cation channel activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900138</classIRI>
<classLabel>negative regulation of phospholipase A2 activity</classLabel>
<deletedAxiom>&apos;negative regulation of phospholipase A2 activity&apos; SubClassOf &apos;regulation of phospholipase A2 activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of phospholipase A2 activity&apos; SubClassOf &apos;negative regulation of phospholipase activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of phospholipase A2 activity&apos; SubClassOf &apos;regulation of phospholipase activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of phospholipase A2 activity&apos; SubClassOf &apos;negative regulation of lipase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042450</classIRI>
<classLabel>L-arginine biosynthetic process via ornithine</classLabel>
<deletedAxiom>&apos;L-arginine biosynthetic process via ornithine&apos; SubClassOf &apos;ornithine metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902800</classIRI>
<classLabel>positive regulation of phosphodiesterase I activity</classLabel>
<newAxiom>&apos;positive regulation of phosphodiesterase I activity&apos; SubClassOf &apos;positive regulation of hydrolase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1900163</classIRI>
<classLabel>positive regulation of phospholipid scramblase activity</classLabel>
<deletedAxiom>&apos;positive regulation of phospholipid scramblase activity&apos; SubClassOf &apos;positive regulation of lipid transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of phospholipid scramblase activity&apos; SubClassOf &apos;positive regulation of transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0042382</classIRI>
<classLabel>paraspeckles</classLabel>
<deletedAxiom>&apos;paraspeckles&apos; SubClassOf &apos;nuclear body&apos;</deletedAxiom>
<newAxiom>&apos;paraspeckles&apos; SubClassOf http://purl.obolibrary.org/obo/GO_0140168</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_1902961</classIRI>
<classLabel>positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process</classLabel>
<deletedAxiom>&apos;positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;positive regulation of amyloid precursor protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;positive regulation of endopeptidase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process&apos; SubClassOf &apos;positive regulation of aspartic-type peptidase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019912</classIRI>
<classLabel>cyclin-dependent protein kinase activating kinase activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein kinase activating kinase activity&apos; SubClassOf &apos;protein kinase activator activity&apos;</deletedAxiom>
<deletedAxiom>&apos;cyclin-dependent protein kinase activating kinase activity&apos; SubClassOf &apos;protein kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019914</classIRI>
<classLabel>cyclin-dependent protein kinase activating kinase regulator activity</classLabel>
<deletedAxiom>&apos;cyclin-dependent protein kinase activating kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclin-dependent protein kinase activating kinase activity&apos;</deletedAxiom>
<newAxiom>&apos;cyclin-dependent protein kinase activating kinase regulator activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;cyclin-dependent protein kinase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0150072</classIRI>
<classLabel>positive regulation of arginase activity</classLabel>
<deletedAxiom>&apos;positive regulation of arginase activity&apos; SubClassOf &apos;positive regulation of hydrolase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of arginase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;arginase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of arginase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;arginase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030200</classIRI>
<classLabel>heparan sulfate proteoglycan catabolic process</classLabel>
<deletedAxiom>&apos;heparan sulfate proteoglycan catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044824</classIRI>
<classLabel>retroviral 3&apos; processing activity</classLabel>
<newAxiom>&apos;retroviral 3&apos; processing activity&apos; SubClassOf &apos;hydrolase activity, acting on ester bonds&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030201</classIRI>
<classLabel>heparan sulfate proteoglycan metabolic process</classLabel>
<deletedAxiom>&apos;heparan sulfate proteoglycan metabolic process&apos; SubClassOf &apos;sulfur compound metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030207</classIRI>
<classLabel>chondroitin sulfate proteoglycan catabolic process</classLabel>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan catabolic process&apos; SubClassOf &apos;glycosaminoglycan catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;chondroitin sulfate proteoglycan catabolic process&apos; SubClassOf &apos;sulfur compound catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030210</classIRI>
<classLabel>heparin proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;heparin proteoglycan biosynthetic process&apos; SubClassOf &apos;proteoglycan biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;heparin proteoglycan biosynthetic process&apos; SubClassOf &apos;biosynthetic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140636</classIRI>
<classLabel>copper import into the mitochondrion</classLabel>
<deletedAxiom>&apos;copper import into the mitochondrion&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0101030</classIRI>
<classLabel>tRNA-guanine transglycosylation</classLabel>
<deletedAxiom>&apos;tRNA-guanine transglycosylation&apos; SubClassOf &apos;tRNA modification&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030199</classIRI>
<classLabel>collagen fibril organization</classLabel>
<deletedAxiom>&apos;collagen fibril organization&apos; SubClassOf &apos;supramolecular fiber organization&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032769</classIRI>
<classLabel>negative regulation of monooxygenase activity</classLabel>
<deletedAxiom>&apos;negative regulation of monooxygenase activity&apos; SubClassOf &apos;negative regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of monooxygenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;monooxygenase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of monooxygenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032770</classIRI>
<classLabel>positive regulation of monooxygenase activity</classLabel>
<deletedAxiom>&apos;positive regulation of monooxygenase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of monooxygenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;monooxygenase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of monooxygenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032773</classIRI>
<classLabel>positive regulation of tyrosinase activity</classLabel>
<deletedAxiom>&apos;positive regulation of tyrosinase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of tyrosinase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0044743</classIRI>
<classLabel>protein transmembrane import into intracellular organelle</classLabel>
<deletedAxiom>&apos;protein transmembrane import into intracellular organelle&apos; SubClassOf &apos;protein transmembrane transport&apos;</deletedAxiom>
<newAxiom>&apos;protein transmembrane import into intracellular organelle&apos; SubClassOf &apos;intracellular protein transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0030150</classIRI>
<classLabel>protein import into mitochondrial matrix</classLabel>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;protein transmembrane import into intracellular organelle&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some &apos;protein targeting to mitochondrion&apos;</deletedAxiom>
<deletedAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;import into the mitochondrion&apos;</deletedAxiom>
<newAxiom>&apos;protein import into mitochondrial matrix&apos; SubClassOf &apos;protein transmembrane transport&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140466</classIRI>
<classLabel>iron-sulfur cluster export from the mitochondrion</classLabel>
<deletedAxiom>&apos;iron-sulfur cluster export from the mitochondrion&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019640</classIRI>
<classLabel>D-glucuronate catabolic process to D-xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;D-glucuronate catabolic process to D-xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;D-glucuronate catabolic process to D-xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140432</classIRI>
<classLabel>5&apos;-hydroxyl dinucleotide hydrolase activity</classLabel>
<deletedAxiom>&apos;5&apos;-hydroxyl dinucleotide hydrolase activity&apos; SubClassOf &apos;RNA nuclease activity&apos;</deletedAxiom>
<newAxiom>&apos;5&apos;-hydroxyl dinucleotide hydrolase activity&apos; SubClassOf &apos;RNA exonuclease activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019697</classIRI>
<classLabel>L-xylitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-xylitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-xylitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0017050</classIRI>
<classLabel>D-erythro-sphingosine kinase activity</classLabel>
<deletedAxiom>&apos;D-erythro-sphingosine kinase activity&apos; SubClassOf &apos;sphingosine kinase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019528</classIRI>
<classLabel>D-arabitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;D-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;D-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019546</classIRI>
<classLabel>arginine deiminase pathway</classLabel>
<newAxiom>&apos;arginine deiminase pathway&apos; SubClassOf http://purl.obolibrary.org/obo/BFO_0000051 some &apos;arginine deiminase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019547</classIRI>
<classLabel>arginine catabolic process to ornithine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to ornithine&apos; SubClassOf &apos;ornithine metabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;arginine catabolic process to ornithine&apos; SubClassOf &apos;arginine catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019548</classIRI>
<classLabel>arginine catabolic process to spermine</classLabel>
<deletedAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;arginine catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;arginine catabolic process to spermine&apos; SubClassOf &apos;arginine metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019554</classIRI>
<classLabel>glutamate catabolic process to oxaloacetate</classLabel>
<deletedAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;glutamate catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;glutamate metabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;dicarboxylic acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;glutamate catabolic process to oxaloacetate&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019569</classIRI>
<classLabel>L-arabinose catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019573</classIRI>
<classLabel>D-arabinose catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;D-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;D-arabinose catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019590</classIRI>
<classLabel>L-arabitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;L-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;L-arabitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019444</classIRI>
<classLabel>L-tryptophan catabolic process to catechol</classLabel>
<deletedAxiom>&apos;L-tryptophan catabolic process to catechol&apos; SubClassOf &apos;aromatic amino acid family catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tryptophan catabolic process to catechol&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tryptophan catabolic process to catechol&apos; SubClassOf &apos;indole-containing compound catabolic process&apos;</deletedAxiom>
<deletedAxiom>&apos;L-tryptophan catabolic process to catechol&apos; SubClassOf &apos;indolalkylamine metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-tryptophan catabolic process to catechol&apos; SubClassOf &apos;L-tryptophan catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032416</classIRI>
<classLabel>negative regulation of sodium:proton antiporter activity</classLabel>
<deletedAxiom>&apos;negative regulation of sodium:proton antiporter activity&apos; SubClassOf &apos;negative regulation of sodium ion transmembrane transporter activity&apos;</deletedAxiom>
<newAxiom>&apos;negative regulation of sodium:proton antiporter activity&apos; SubClassOf &apos;regulation of sodium ion transmembrane transporter activity&apos;</newAxiom>
<newAxiom>&apos;negative regulation of sodium:proton antiporter activity&apos; SubClassOf &apos;negative regulation of ion transmembrane transporter activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019464</classIRI>
<classLabel>glycine decarboxylation via glycine cleavage system</classLabel>
<newAxiom>&apos;glycine decarboxylation via glycine cleavage system&apos; SubClassOf &apos;ammonium ion metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032429</classIRI>
<classLabel>regulation of phospholipase A2 activity</classLabel>
<deletedAxiom>&apos;regulation of phospholipase A2 activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002211 some &apos;phospholipase A2 activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;regulation of phospholipase A2 activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002211 some &apos;phospholipase A2 activity&apos;</deletedAxiom>
<deletedAxiom>&apos;regulation of phospholipase A2 activity&apos; SubClassOf &apos;regulation of phospholipase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032431</classIRI>
<classLabel>activation of phospholipase A2 activity</classLabel>
<deletedAxiom>&apos;activation of phospholipase A2 activity&apos; SubClassOf &apos;positive regulation of phospholipase A2 activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0032430</classIRI>
<classLabel>positive regulation of phospholipase A2 activity</classLabel>
<deletedAxiom>&apos;positive regulation of phospholipase A2 activity&apos; SubClassOf &apos;regulation of phospholipase A2 activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019470</classIRI>
<classLabel>4-hydroxyproline catabolic process</classLabel>
<deletedAxiom>&apos;4-hydroxyproline catabolic process&apos; SubClassOf &apos;alpha-amino acid catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;4-hydroxyproline catabolic process&apos; SubClassOf &apos;L-amino acid catabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019488</classIRI>
<classLabel>ribitol catabolic process to xylulose 5-phosphate</classLabel>
<deletedAxiom>&apos;ribitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate biosynthetic process&apos;</deletedAxiom>
<newAxiom>&apos;ribitol catabolic process to xylulose 5-phosphate&apos; SubClassOf &apos;xylulose 5-phosphate metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019495</classIRI>
<classLabel>proline catabolic process to 2-oxoglutarate</classLabel>
<deletedAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;proline catabolic process&apos;</deletedAxiom>
<newAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;carboxylic acid catabolic process&apos;</newAxiom>
<newAxiom>&apos;proline catabolic process to 2-oxoglutarate&apos; SubClassOf &apos;proline metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140141</classIRI>
<classLabel>mitochondrial potassium ion transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial potassium ion transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140140</classIRI>
<classLabel>mitochondrial guanine nucleotide transmembrane transport</classLabel>
<deletedAxiom>&apos;mitochondrial guanine nucleotide transmembrane transport&apos; SubClassOf &apos;mitochondrial transmembrane transport&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010908</classIRI>
<classLabel>regulation of heparan sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;regulation of heparan sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;regulation of sulfur metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010909</classIRI>
<classLabel>positive regulation of heparan sulfate proteoglycan biosynthetic process</classLabel>
<deletedAxiom>&apos;positive regulation of heparan sulfate proteoglycan biosynthetic process&apos; SubClassOf &apos;positive regulation of sulfur metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010925</classIRI>
<classLabel>positive regulation of inositol-polyphosphate 5-phosphatase activity</classLabel>
<deletedAxiom>&apos;positive regulation of inositol-polyphosphate 5-phosphatase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002213 some &apos;inositol-polyphosphate 5-phosphatase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;positive regulation of inositol-polyphosphate 5-phosphatase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002213 some &apos;inositol-polyphosphate 5-phosphatase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;positive regulation of inositol-polyphosphate 5-phosphatase activity&apos; SubClassOf &apos;positive regulation of phosphatase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010956</classIRI>
<classLabel>negative regulation of calcidiol 1-monooxygenase activity</classLabel>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;negative regulation of vitamin D biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcidiol 1-monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;negative regulation of hormone biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;negative regulation of monooxygenase activity&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; EquivalentTo &apos;biological regulation&apos; and (http://purl.obolibrary.org/obo/RO_0002212 some &apos;calcidiol 1-monooxygenase activity&apos;)</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;negative regulation of alcohol biosynthetic process&apos;</deletedAxiom>
<deletedAxiom>&apos;negative regulation of calcidiol 1-monooxygenase activity&apos; SubClassOf &apos;regulation of calcidiol 1-monooxygenase activity&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0009972</classIRI>
<classLabel>cytidine deamination</classLabel>
<deletedAxiom>&apos;cytidine deamination&apos; SubClassOf &apos;cytidine catabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019311</classIRI>
<classLabel>sorbose metabolic process</classLabel>
<deletedAxiom>&apos;sorbose metabolic process&apos; SubClassOf &apos;hexose metabolic process&apos;</deletedAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0019312</classIRI>
<classLabel>L-sorbose metabolic process</classLabel>
<deletedAxiom>&apos;L-sorbose metabolic process&apos; SubClassOf &apos;sorbose metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;L-sorbose metabolic process&apos; SubClassOf &apos;hexose metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0010980</classIRI>
<classLabel>positive regulation of vitamin D 24-hydroxylase activity</classLabel>
<deletedAxiom>&apos;positive regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;positive regulation of monooxygenase activity&apos;</deletedAxiom>
<newAxiom>&apos;positive regulation of vitamin D 24-hydroxylase activity&apos; SubClassOf &apos;positive regulation of oxidoreductase activity&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046937</classIRI>
<classLabel>phytochelatin metabolic process</classLabel>
<deletedAxiom>&apos;phytochelatin metabolic process&apos; SubClassOf &apos;secondary metabolic process&apos;</deletedAxiom>
<newAxiom>&apos;phytochelatin metabolic process&apos; SubClassOf &apos;primary metabolic process&apos;</newAxiom>
</changedClass>
<changedClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0046938</classIRI>
<classLabel>phytochelatin biosynthetic process</classLabel>
<deletedAxiom>&apos;phytochelatin biosynthetic process&apos; SubClassOf &apos;secondary metabolite biosynthetic process&apos;</deletedAxiom>
</changedClass>
</changedClasses>
<newClasses>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120559</classIRI>
<classLabel>phosphatidylethanolamine lysophospholipase activity</classLabel>
<newAxiom>'phosphatidylethanolamine lysophospholipase activity' SubClassOf 'lysophospholipase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120558</classIRI>
<classLabel>lysophospholipase activity</classLabel>
<newAxiom>'lysophospholipase activity' SubClassOf 'carboxylic ester hydrolase activity'</newAxiom>
<newAxiom>'lysophospholipase activity' SubClassOf 'phospholipase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120557</classIRI>
<classLabel>farnesyl diphosphatase activity</classLabel>
<newAxiom>'farnesyl diphosphatase activity' SubClassOf 'polyprenyl diphosphate phosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120556</classIRI>
<classLabel>polyprenyl diphosphate phosphatase activity</classLabel>
<newAxiom>'polyprenyl diphosphate phosphatase activity' SubClassOf 'isoprenoid diphosphate phosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120555</classIRI>
<classLabel>NADH dehydrogenase (ubiquinone) (non-electrogenic) activity</classLabel>
<newAxiom>'NADH dehydrogenase (ubiquinone) (non-electrogenic) activity' SubClassOf 'NADH dehydrogenase (quinone) (non-electrogenic) activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120565</classIRI>
<classLabel>dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity</classLabel>
<newAxiom>'dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity' SubClassOf 'alpha-1,2-mannosyltransferase activity'</newAxiom>
<newAxiom>'dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity' SubClassOf 'GPI mannosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120564</classIRI>
<classLabel>dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity</classLabel>
<newAxiom>'dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity' SubClassOf 'GPI mannosyltransferase activity'</newAxiom>
<newAxiom>'dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity' SubClassOf 'alpha-1,2-mannosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120563</classIRI>
<classLabel>dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity</classLabel>
<newAxiom>'dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity' SubClassOf 'GPI mannosyltransferase activity'</newAxiom>
<newAxiom>'dol-P-Man:Man(1)GlcN-acyl-PI alpha-1,6-mannosyltransferase activity' SubClassOf 'alpha-1,6-mannosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120562</classIRI>
<classLabel>GlcNAc(2)-PP-Dol mannosyltransferase activity</classLabel>
<newAxiom>'GlcNAc(2)-PP-Dol mannosyltransferase activity' SubClassOf 'mannosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120561</classIRI>
<classLabel>phosphatidylinositol lysophospholipase activity</classLabel>
<newAxiom>'phosphatidylinositol lysophospholipase activity' SubClassOf 'lysophospholipase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120560</classIRI>
<classLabel>phosphatidylserine lysophospholipase activity</classLabel>
<newAxiom>'phosphatidylserine lysophospholipase activity' SubClassOf 'lysophospholipase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120554</classIRI>
<classLabel>2-aminobutanoate transaminase activity</classLabel>
<newAxiom>'2-aminobutanoate transaminase activity' SubClassOf 'transaminase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120553</classIRI>
<classLabel>farnesal dehydrogenase (NAD+) activity</classLabel>
<newAxiom>'farnesal dehydrogenase (NAD+) activity' SubClassOf 'oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120552</classIRI>
<classLabel>branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA</classLabel>
<newAxiom>'branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA' SubClassOf 'fatty-acyl-CoA metabolic process'</newAxiom>
<newAxiom>'branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'branched-chain amino acid catabolic process'</newAxiom>
<newAxiom>'branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA' SubClassOf 'carboxylic acid metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120551</classIRI>
<classLabel>2-oxoglutarate decarboxylation to succinyl-CoA</classLabel>
<newAxiom>'2-oxoglutarate decarboxylation to succinyl-CoA' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'tricarboxylic acid cycle'</newAxiom>
<newAxiom>'2-oxoglutarate decarboxylation to succinyl-CoA' SubClassOf 'succinyl-CoA biosynthetic process'</newAxiom>
<newAxiom>'2-oxoglutarate decarboxylation to succinyl-CoA' SubClassOf '2-oxoglutarate metabolic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0120550</classIRI>
<classLabel>methyltransferase cap2 activity</classLabel>
<newAxiom>'methyltransferase cap2 activity' SubClassOf 'RNA methyltransferase activity'</newAxiom>
<newAxiom>'methyltransferase cap2 activity' SubClassOf 'O-methyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160253</classIRI>
<classLabel>de novo tRNA queuosine(34) biosynthetic process</classLabel>
<newAxiom>'de novo tRNA queuosine(34) biosynthetic process' SubClassOf 'tRNA queuosine(34) biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160259</classIRI>
<classLabel>endoplasmic reticulum membrane-lipid droplet contact site</classLabel>
<newAxiom>'endoplasmic reticulum membrane-lipid droplet contact site' SubClassOf 'cellular anatomical structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160258</classIRI>
<classLabel>endoplasmic reticulum-trans-Golgi network membrane contact site</classLabel>
<newAxiom>'endoplasmic reticulum-trans-Golgi network membrane contact site' SubClassOf 'organelle membrane contact site'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160257</classIRI>
<classLabel>complement activation, GZMK pathway</classLabel>
<newAxiom>'complement activation, GZMK pathway' SubClassOf 'innate immune response'</newAxiom>
<newAxiom>'complement activation, GZMK pathway' SubClassOf 'complement activation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160256</classIRI>
<classLabel>L-lysine transmembrane import into the mitochondrion</classLabel>
<newAxiom>'L-lysine transmembrane import into the mitochondrion' SubClassOf 'L-lysine transmembrane transport'</newAxiom>
<newAxiom>'L-lysine transmembrane import into the mitochondrion' SubClassOf 'import into the mitochondrion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160255</classIRI>
<classLabel>tRNA queuosine(34) biosynthetic process from salvaged queuine</classLabel>
<newAxiom>'tRNA queuosine(34) biosynthetic process from salvaged queuine' SubClassOf 'tRNA queuosine(34) biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160254</classIRI>
<classLabel>tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors</classLabel>
<newAxiom>'tRNA queuosine(34) biosynthetic process from salvaged queuosine or its precursors' SubClassOf 'tRNA queuosine(34) biosynthetic process'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160264</classIRI>
<classLabel>histone H1N76/N77 asparagine deamidase activity</classLabel>
<newAxiom>'histone H1N76/N77 asparagine deamidase activity' SubClassOf 'histone H1 asparagine deamidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160263</classIRI>
<classLabel>histone H1K75 acetyltransferase activity</classLabel>
<newAxiom>'histone H1K75 acetyltransferase activity' SubClassOf 'histone H1 acetyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160262</classIRI>
<classLabel>histone H1 acetyltransferase activity</classLabel>
<newAxiom>'histone H1 acetyltransferase activity' SubClassOf 'histone acetyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160261</classIRI>
<classLabel>histone H1 asparagine deamidase activity</classLabel>
<newAxiom>'histone H1 asparagine deamidase activity' SubClassOf 'protein asparagine deamidase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160260</classIRI>
<classLabel>protein asparagine deamidase activity</classLabel>
<newAxiom>'protein asparagine deamidase activity' SubClassOf 'catalytic activity, acting on a protein'</newAxiom>
<newAxiom>'protein asparagine deamidase activity' SubClassOf 'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160269</classIRI>
<classLabel>sweat secretion</classLabel>
<newAxiom>'sweat secretion' SubClassOf 'secretion by tissue'</newAxiom>
<newAxiom>'sweat secretion' SubClassOf 'body fluid secretion'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160268</classIRI>
<classLabel>histone H1K26me2 reader activity</classLabel>
<newAxiom>'histone H1K26me2 reader activity' SubClassOf 'histone H1 reader activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160267</classIRI>
<classLabel>histone H1K26me1 reader activity</classLabel>
<newAxiom>'histone H1K26me1 reader activity' SubClassOf 'histone H1 reader activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160266</classIRI>
<classLabel>anestrus phase</classLabel>
<newAxiom>'anestrus phase' SubClassOf 'biological phase'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160265</classIRI>
<classLabel>O-fucosylpeptide 3-beta-glucosyltransferase activity</classLabel>
<newAxiom>'O-fucosylpeptide 3-beta-glucosyltransferase activity' SubClassOf 'UDP-glucosyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160273</classIRI>
<classLabel>RNA 2'-phosphatase activity</classLabel>
<newAxiom>'RNA 2'-phosphatase activity' SubClassOf 'catalytic activity, acting on RNA'</newAxiom>
<newAxiom>'RNA 2'-phosphatase activity' SubClassOf 'phosphatase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160272</classIRI>
<classLabel>RNA 2',3'-cyclic phosphatase activity</classLabel>
<newAxiom>'RNA 2',3'-cyclic phosphatase activity' SubClassOf 'phosphatase activity'</newAxiom>
<newAxiom>'RNA 2',3'-cyclic phosphatase activity' SubClassOf 'catalytic activity, acting on RNA'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160271</classIRI>
<classLabel>FERRY complex</classLabel>
<newAxiom>'FERRY complex' SubClassOf 'protein-containing complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0160270</classIRI>
<classLabel>phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity</classLabel>
<newAxiom>'phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity' SubClassOf 'phospholipid transfer activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170069</classIRI>
<classLabel>geranylgeranyltransferase-III complex</classLabel>
<newAxiom>'geranylgeranyltransferase-III complex' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'cytosol'</newAxiom>
<newAxiom>'geranylgeranyltransferase-III complex' SubClassOf 'transferase complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0170068</classIRI>
<classLabel>geranylgeranyltransferase type III activity</classLabel>
<newAxiom>'geranylgeranyltransferase type III activity' SubClassOf 'protein geranylgeranyltransferase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180056</classIRI>
<classLabel>citrate:2-oxoglutarate antiporter activity</classLabel>
<newAxiom>'citrate:2-oxoglutarate antiporter activity' SubClassOf 'antiporter activity'</newAxiom>
<newAxiom>'citrate:2-oxoglutarate antiporter activity' SubClassOf 'citrate secondary active transmembrane transporter activity'</newAxiom>
<newAxiom>'citrate:2-oxoglutarate antiporter activity' SubClassOf 'alpha-ketoglutarate transmembrane transporter activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180055</classIRI>
<classLabel>response to metal ion starvation</classLabel>
<newAxiom>'response to metal ion starvation' SubClassOf 'response to starvation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180054</classIRI>
<classLabel>ribosome translocase activity</classLabel>
<newAxiom>'ribosome translocase activity' SubClassOf 'GTPase motor activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180060</classIRI>
<classLabel>siderophore-dependent iron import pathway</classLabel>
<newAxiom>'siderophore-dependent iron import pathway' SubClassOf 'iron import into cell'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0180061</classIRI>
<classLabel>native siderophore export across plasma membrane</classLabel>
<newAxiom>'native siderophore export across plasma membrane' SubClassOf 'siderophore-dependent iron import pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_7770001</classIRI>
<classLabel>mitochondrial pyruvate carrier complex</classLabel>
<newAxiom>'mitochondrial pyruvate carrier complex' SubClassOf 'transmembrane transporter complex'</newAxiom>
<newAxiom>'mitochondrial pyruvate carrier complex' SubClassOf 'inner mitochondrial membrane protein complex'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140169</classIRI>
<classLabel>3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity</classLabel>
<newAxiom>'3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity' SubClassOf 'steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140168</classIRI>
<classLabel>nuclear ribonucleoprotein granule</classLabel>
<newAxiom>'nuclear ribonucleoprotein granule' EquivalentTo 'ribonucleoprotein granule' and (http://purl.obolibrary.org/obo/BFO_0000050 some 'nucleoplasm')</newAxiom>
<newAxiom>'nuclear ribonucleoprotein granule' SubClassOf 'ribonucleoprotein granule'</newAxiom>
<newAxiom>'nuclear ribonucleoprotein granule' SubClassOf 'nuclear body'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140174</classIRI>
<classLabel>(2R)-2-hydroxycarboxylate dehydrogenase activity</classLabel>
<newAxiom>'(2R)-2-hydroxycarboxylate dehydrogenase activity' SubClassOf '(2R)-oxo-acid reductase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140173</classIRI>
<classLabel>histone H2AS128phos reader activity</classLabel>
<newAxiom>'histone H2AS128phos reader activity' SubClassOf 'histone H2A reader activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140172</classIRI>
<classLabel>histone H2AS121phos reader activity</classLabel>
<newAxiom>'histone H2AS121phos reader activity' SubClassOf 'histone H2A reader activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140171</classIRI>
<classLabel>L-lactate dehydrogenase activity</classLabel>
<newAxiom>'L-lactate dehydrogenase activity' SubClassOf 'lactate dehydrogenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140175</classIRI>
<classLabel>(2R)-2-hydroxyacid dehydrogenase (NAD+) activity</classLabel>
<newAxiom>'(2R)-2-hydroxyacid dehydrogenase (NAD+) activity' SubClassOf 'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140170</classIRI>
<classLabel>D-lactate dehydrogenase (FAD) activity</classLabel>
<newAxiom>'D-lactate dehydrogenase (FAD) activity' SubClassOf 'D-lactate dehydrogenase activity'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140158</classIRI>
<classLabel>von-Willerbrand-factor-A-domain-rich collagen trimer</classLabel>
<newAxiom>'von-Willerbrand-factor-A-domain-rich collagen trimer' SubClassOf 'collagen trimer'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140163</classIRI>
<classLabel>venom-mediated suppression of bradykinin-dependent vasodilation</classLabel>
<newAxiom>'venom-mediated suppression of bradykinin-dependent vasodilation' SubClassOf 'venom-mediated perturbation of G protein-coupled receptor signaling pathway'</newAxiom>
<newAxiom>'venom-mediated suppression of bradykinin-dependent vasodilation' SubClassOf 'venom-mediated perturbation of blood circulation'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140162</classIRI>
<classLabel>venom-mediated vasodilation by activation of bradykinin-dependent signaling</classLabel>
<newAxiom>'venom-mediated vasodilation by activation of bradykinin-dependent signaling' SubClassOf 'venom-mediated vasodilation'</newAxiom>
<newAxiom>'venom-mediated vasodilation by activation of bradykinin-dependent signaling' SubClassOf 'venom-mediated perturbation of G protein-coupled receptor signaling pathway'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140167</classIRI>
<classLabel>histone locus body assembly</classLabel>
<newAxiom>'histone locus body assembly' SubClassOf 'membraneless organelle assembly'</newAxiom>
<newAxiom>'histone locus body assembly' SubClassOf 'nuclear body organization'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140166</classIRI>
<classLabel>venom-mediated vasodilation via suppression of angiotensin maturation</classLabel>
<newAxiom>'venom-mediated vasodilation via suppression of angiotensin maturation' SubClassOf 'venom-mediated vasodilation'</newAxiom>
<newAxiom>'venom-mediated vasodilation via suppression of angiotensin maturation' SubClassOf 'venom-mediated perturbation of signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140165</classIRI>
<classLabel>venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling</classLabel>
<newAxiom>'venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling' SubClassOf 'venom-mediated vasodilation'</newAxiom>
<newAxiom>'venom-mediated vasodilation by activation of nitric oxide-cGMP-mediated signaling' SubClassOf 'venom-mediated perturbation of signal transduction'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140149</classIRI>
<classLabel>non-collagenous component of interstitial matrix</classLabel>
<newAxiom>'non-collagenous component of interstitial matrix' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'interstitial matrix'</newAxiom>
<newAxiom>'non-collagenous component of interstitial matrix' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140148</classIRI>
<classLabel>gel phase of basement membrane</classLabel>
<newAxiom>'gel phase of basement membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'basement membrane'</newAxiom>
<newAxiom>'gel phase of basement membrane' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140152</classIRI>
<classLabel>collagenous component of interstitial matrix</classLabel>
<newAxiom>'collagenous component of interstitial matrix' SubClassOf 'external encapsulating structure'</newAxiom>
<newAxiom>'collagenous component of interstitial matrix' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'solid phase of interstitial matrix'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140151</classIRI>
<classLabel>solid phase of interstitial matrix</classLabel>
<newAxiom>'solid phase of interstitial matrix' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'interstitial matrix'</newAxiom>
<newAxiom>'solid phase of interstitial matrix' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140150</classIRI>
<classLabel>gel phase of interstitial matrix</classLabel>
<newAxiom>'gel phase of interstitial matrix' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'interstitial matrix'</newAxiom>
<newAxiom>'gel phase of interstitial matrix' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140156</classIRI>
<classLabel>multiplexin collagen trimer</classLabel>
<newAxiom>'multiplexin collagen trimer' SubClassOf 'collagen trimer'</newAxiom>
<newAxiom>'multiplexin collagen trimer' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'collagenous component of basement membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140155</classIRI>
<classLabel>hexagonal collagen network of basement membrane</classLabel>
<newAxiom>'hexagonal collagen network of basement membrane' SubClassOf 'collagen network'</newAxiom>
<newAxiom>'hexagonal collagen network of basement membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'collagenous component of basement membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140154</classIRI>
<classLabel>chicken-wire-like collagen network</classLabel>
<newAxiom>'chicken-wire-like collagen network' SubClassOf 'complex of collagen trimers'</newAxiom>
<newAxiom>'chicken-wire-like collagen network' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'collagenous component of basement membrane'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140153</classIRI>
<classLabel>FACIT collagen complex</classLabel>
<newAxiom>'FACIT collagen complex' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'collagenous component of interstitial matrix'</newAxiom>
<newAxiom>'FACIT collagen complex' SubClassOf 'complex of collagen trimers'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140139</classIRI>
<classLabel>solid phase of basement membrane</classLabel>
<newAxiom>'solid phase of basement membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'basement membrane'</newAxiom>
<newAxiom>'solid phase of basement membrane' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140144</classIRI>
<classLabel>non-collagenous component of basement membrane</classLabel>
<newAxiom>'non-collagenous component of basement membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'solid phase of basement membrane'</newAxiom>
<newAxiom>'non-collagenous component of basement membrane' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
<newClass>
<classIRI>http://purl.obolibrary.org/obo/GO_0140143</classIRI>
<classLabel>collagenous component of basement membrane</classLabel>
<newAxiom>'collagenous component of basement membrane' SubClassOf http://purl.obolibrary.org/obo/BFO_0000050 some 'solid phase of basement membrane'</newAxiom>
<newAxiom>'collagenous component of basement membrane' SubClassOf 'external encapsulating structure'</newAxiom>
</newClass>
</newClasses>
<deletedClasses>
</deletedClasses>
</diffReport>