FEF 25-75 Percent Predicted Value
definition: The percent ratio of a patient's best FEF 25-75 value divided by the expected or predicted FEF 25-75 value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: percent
type: Class
type: QualityVariable

Lab confirmed result
subclass of: SIO_001167
type: Class

2, 2', 3, 4, 4'-Pentabromodiphenyl ether
notation: BDE85
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Vineland Motor Skills Domain
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
notation: VOCPHE
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Uncle
notation: 192
definition: The brother of your father or mother or the husband of your aunt.
subclass of: Relative
type: Class
type: QualityValue

Daily Exposure to Second Hand Smoke
notation: 250
subclass of: environmental tobacco smoke exposure
type: Class
type: QualityValue

Raw Score
subclass of: Physical And Mental Assessment
subclass of: Score
subclass of: NCIT C25338
type: Class
type: QuantityVariable

unit per liter
notation: U/l
type: SIO_000074

1-hydroxyphenanthrene
notation: PHEN1
subclass of: PAH
type: Class

siemens
notation: 1/AV
type: SIO_000074

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
notation: HEMA2
subclass of: Volatile Organic Compound
type: Class

2, 2', 4'-Tribromodiphenyl ether
notation: BDE17
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Grandfather
definition: The father of your father or mother.
subclass of: Ancestor
type: Class

N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
notation: VOC1DC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Several times a week exposure to second hand smoke
notation: 251
subclass of: environmental tobacco smoke exposure
type: Class
type: QualityValue

Vineland Communication Domain
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

unit per milliliter
notation: U/ml
type: SIO_000074

o-Xylene
notation: OXY
definition: O-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
subclass of: Volatile Organic Compound
type: Class

Cell

mono-n-butylphthalate (BzBP, DnBP)
notation: MnBP
subclass of: Phthalate
type: Class

trans, trans -Muconic acid
notation: MU
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
notation: BDE209
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Lipemic
subclass of: SIO_001167
type: Class

Interferon gamma
notation: IFNG
subclass of: Protein
type: Class

N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
notation: VOCGAM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Grandmother
notation: 190
definition: The mother of your father or mother.
subclass of: Ancestor
type: Class
type: QualityValue

FVC Percent Predicted Value
definition: The percent ratio of a patient's best FVC value divided by the expected or predicted FVC value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: CMO_0000251
subclass of: Restriction
  on property: hasUnit
  has value: percent
type: Class
type: QualityVariable

Vineland Daily Living Skills Domain
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

electronvolt
notation: eV
type: SIO_000074

curie
notation: Ci
type: SIO_000074

Language
editorial note: Needs to be rooted in sio
subclass of: Acculturation
type: Class
type: QualityVariable

Heptyl paraben
notation: HePB
subclass of: Paraben
type: Class

2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
notation: BDE183
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Laboratory Result
definition: A measurement taken on a sample.
subclass of: Indicator
type: Class

Aunt
notation: 191
definition: The sister of your father or mother or the wife of your uncle.
subclass of: Relative
type: Class
type: QualityValue

Vineland Socialization Domain
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

FEV1 Percent Predicted Value
definition: The percent ratio of a patient's best FEV1 value divided by the expected or predicted FEV1 value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: CMO_0000254
subclass of: Restriction
  on property: hasUnit
  has value: percent
type: Class
type: QualityVariable

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
notation: VOCMB3
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Monocyclohexyl phthalate
notation: MCHP
subclass of: Phthalate
type: Class

FEF 25-75 Predicted Value
definition: The expected or predicted FEF 25-75 value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

Strontium
notation: Sr
definition: STRONTIUM is an element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.
subclass of: Metal
type: Class

Perfluorooctanoic acid
notation: PFOA
subclass of: PFC
type: Class

becquerel
notation: Bq
type: SIO_000074

watt per meter kelvin
notation: W/mK
type: SIO_000074

Some College
notation: 85
definition: Indicates that a person has attended college but that they did not receive any degree.
subclass of: Educational Status
subclass of: Higher Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

High-Performance Liquid Chromatography
definition: High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.
subclass of: Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
type: Class

monoisononyl phthalate
notation: MIP
editorial note: Duplicate of mINP?
subclass of: Phthalate
type: Class

First Void Urination
notation: 356
subclass of: Urination
type: Class
type: QualityValue

Spirometry Outcomes Did Not Meet Guidelines
notation: 281
subclass of: Spirometry Outcome
subclass of: Restriction
  some values from: SIO_001310
  on property: SIO_000217
type: Class
type: QualityValue

Washing Machine Count
definition: Number of machines used for washing clothes in the home.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Mullens Verbal Domain
definition: A composite score derived from the Mullens Receptive Language and Mullens Expressive Language scales.
subclass of: Physical And Mental Assessment
subclass of: Restriction
  some values from: CAO_03174
  on property: wasDerivedFrom
subclass of: Restriction
  some values from: CAO_03173
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Daily Smoker
notation: 157
subclass of: Smoking Status
type: Class
type: QualityValue

volt per meter
notation: V/m
type: SIO_000074

abnormal cell
subclass of: Cell
type: Class

Interleukin-6
notation: IL6
definition: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
subclass of: Protein
type: Class

Sputum
definition: Matter ejected from the lungs, bronchi, and trachea, through the mouth. [database_cross_reference: Dorlands_Medical_Dictionary:MerckSource]
subclass of: Bodily Fluid
type: Class

Nitrogen Oxides
subclass of: Air Pollutant
subclass of: Metabolite
label: Nitrogen Oxide
type: Class

Has taken asthma control medications
notation: 282
disjoint with: Never takes asthma control medications
subclass of: Asthma Controller Use
type: Class
type: QualityValue

Weight for Height Z-Score
definition: Z-Score of the weight/height ratio at a given age.
subclass of: SIO_001245
subclass of: Z-Score
type: Class
type: QuantityVariable

t, t-Muconic acid(ng/mL)
notation: VOCMUC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Occasional Smoker
notation: 158
subclass of: Smoking Status
type: Class
type: QualityValue

First Void Urine
notation: 357
subclass of: Urine
subclass of: Restriction
  some values from: First Void Urination
  on property: SIO_000312
type: Class
type: QualityValue

N-Acetyl-S-(trichlorovinyl)-L-cysteine
notation: TCVMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

docosanoic acid
notation: C220
definition: A straight-chain, C22, long-chain saturated fatty acid.
subclass of: Fatty Acid
type: Class

Mullens Non-Verbal Domain
definition: A composite score derived from the Mullens Visual Reception and Mullens Fine Motor scales..
subclass of: Physical And Mental Assessment
subclass of: Restriction
  some values from: CAO_03172
  on property: wasDerivedFrom
subclass of: Restriction
  some values from: CAO_03171
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

electric field strength unit
notation: Efs
type: SIO_000074

Gray
notation: Gy
type: SIO_000074

esophageal disease
subclass of: SIO_010299
type: Class

microgram per gram
notation: ug/g
type: SIO_000074

Saliva
definition: A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. [database_cross_reference: http://en.wikipedia.org/wiki/Saliva][database_cross_reference: GO:0046541]
subclass of: Bodily Fluid
type: Class

3-hydroxyphenanthrene
notation: PHEN3
subclass of: PAH
type: Class

Plasma
definition: The liquid component of blood, in which erythrocytes are suspended. [database_cross_reference: http://orcid.org/0000-0002-6601-2165]
subclass of: Blood Component
type: Class

Mono-n-octyl phthalate
notation: MOP
subclass of: Phthalate
type: Class

Floor Type
definition: Type of material that makes up the floor.
subclass of: SIO_000004
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

mono-isodecyl phthalate
notation: mIDP
subclass of: Phthalate
type: Class

Asian Non-Hispanic
notation: 217
subclass of: Non-Hispanic Ethnicity
subclass of: Asian
type: Class
type: QualityValue

VCR Player Count
definition: Number of devices that play VCRs in the home.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

millisievert
notation: mSv
type: SIO_000074

Annual Income $30,000 to $60,000
notation: 349
subclass of: Household Income
type: Class
type: QualityValue

Occasional E-Cigarette Use
notation: 155
subclass of: E-Cigarette Use
type: Class
type: QualityValue

Spirometry Outcome
subclass of: Physical And Mental Assessment
subclass of: NCIT C123984
subclass of: Restriction
  some values from: NCIT C85397
  on property: SIO_001157
type: Class
type: QualityVariable

kilodalton
notation: kDa
type: SIO_000074

sievert
notation: Sv
type: SIO_000074

Perfluorononanoic acid
notation: PFNA
subclass of: PFC
type: Class

Interleukin-17F
notation: IL17F
subclass of: Protein
type: Class

SIO_000980
notation: 107
type: QualityValue

Behavioral Experimental Paradigm Condition
subclass of: Neurocognitive Assessment
type: Class

Gravida
definition: Pregnancy Count, regardless of whether pregnancy was carried to Term.
subclass of: SIO_000794
subclass of: Pregnancy Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

American Indian Non-Hispanic
notation: 218
subclass of: Non-Hispanic Ethnicity
subclass of: American Indian Or Alaskan Native
type: Class
type: QualityValue

Annual Income More Than $60,000
notation: 350
subclass of: Household Income
type: Class
type: QualityValue

mono-isopropyl phthalate
notation: mIPrP
editorial note: Duplicate of MiPP?
subclass of: Phthalate
type: Class

Vacuum Cleaner Count
definition: Number of appliances in home used for cleaning rugs.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Daily E-Cigarette Use
notation: 156
subclass of: E-Cigarette Use
type: Class
type: QualityValue

Spirometry Outcomes Met Guidelines
notation: 280
subclass of: Spirometry Outcome
subclass of: Restriction
  some values from: SIO_001312
  on property: SIO_000217
type: Class
type: QualityValue

absorbance unit
notation: AU
type: SIO_000074

roentgen
notation: Roentgen
type: SIO_000074

dalton
notation: Da
type: SIO_000074

SIO_000981
notation: 108
type: QualityValue

1, 2-Dichloroethane
notation: DE12
definition: Ethylene Dichloride is a clear, colorless, oily, synthetic, flammable liquid chlorinated hydrocarbon with a pleasant chloroform-like smell that emits toxic fumes of hydrochloric acid when heated to decomposition. Ethylene dichloride is primarily used to produce vinyl chloride. Inhalation exposure to this substance induces respiratory distress, nausea and vomiting and affects the central nervous system, liver and kidneys. It is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
subclass of: Volatile Organic Compound
type: Class

Rarely exposed to second hand smoke from E-cigarettes
notation: 258
subclass of: environmental e-cigarette smoke exposure
type: Class
type: QualityValue

Autism Spectrum Disorder
notation: 151
subclass of: Developmental Disorder of Mental Health
type: Class
type: QualityValue

DERP1 Dust Mite Allergen
subclass of: Allergen
type: Class

Demographic
editorial note: SDD-2016-1431-P01_SG_Dictionary_SDD_v1.xlsx
definition: Demographics are quantifiable characteristics of a given population.
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Drug History
notation: 14
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityVariable

Markedly hemolyzed
subclass of: SIO_001167
type: Class

Monocyte
definition: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
subclass of: Lymphocyte
type: Class

kilogram per square meter
notation: kg/m2
type: SIO_000074

parts per trillion
notation: ppt
type: SIO_000074

American Indian Or Alaskan Native
notation: 5
definition: A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal affiliation or community attachment.
subclass of: Race
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Ontology
imports: stato.owl
imports: cl-basic.owl
imports: prov
imports: cmo.owl
imports: uo.owl
imports: cogat
comment: The Human Health Exposure Analysis Resource (HHEAR) measures exposures that cover the breadth of the “exposome,” which encompasses all environmental exposures including chemical, physical, and biological stressors, as well as lifestyle and social environments, from conception through adulthood. Read more at: https://hhearprogram.org
imports: sio.owl
version IRI: http://purl.org/twc/HHEAR/1.5

DERF1 Dust Mite Allergen
subclass of: Allergen
type: Class

Antimalarial Use
definition: A subclass of medical intervention that characterizes a patient's experience with using an antimalarial. Subclasses detail the level to which a patient has used such a medication to prevent or treat malaria.
subclass of: SIO_001398
subclass of: Pharmacotherapy
subclass of: Restriction
  some values from: SIO_000393
  on property: SIO_000291
subclass of: Restriction
  some values from: Antimalarial
  on property: SIO_000230
type: Class

Dental Fillings
notation: 13
subclass of: Oral Health
type: Class
type: QualityValue

Liquid Chromotography-Multistage Mass Spectrometery
subclass of: MassSpectrometry
type: Class

neural cell
subclass of: Cell
type: Class

Bisphenol F
notation: BPF
subclass of: Environmental Phenol
type: Class

Computer
definition: A machine used for computation and much more.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Drinking Water
definition: Drinking water is water which may be consumed by humans with no adverse effects on their health.
definition: Drinking Water
subclass of: Environmental Material
type: Class

parts per billion
notation: ppb
type: SIO_000074

candela per square meter
notation: cd/m2
type: SIO_000074

Non-Biological Relative
definition: People that are considered relatives but are not related by blood. This includes relatives by marriage, adoption, or fosterage.
subclass of: Relative
type: Class

Fms-related tyrosine kinase 3 ligand
notation: FLT3L
subclass of: Protein
type: Class

Several times a week exposure to second hand smoke from E-cigarettes
notation: 256
subclass of: environmental e-cigarette smoke exposure
type: Class
type: QualityValue

Mouse Allergen
subclass of: Allergen
type: Class

glucose
definition: An aldohexose used as a source of energy and metabolic intermediate.
subclass of: Metabolite
subclass of: Biological Response
type: Class

Developmental Quality
definition: Refers to which stage of development a person is in.
subclass of: SIO_000475
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Gas Chromatography Instrument
definition: Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture (the relative amounts of such components can also be determined). In some situations, GC may help in identifying a compound. In preparative chromatography, GC can be used to prepare pure compounds from a mixture.
subclass of: Chromatography Instrument
was approved by: PER-Jim-McCusker
type: Class

Perfluorobutanoic acid
notation: PFBA
subclass of: PFC
type: Class

blood monocyte count
subclass of: SIO_000794
type: Class

gram per mole
notation: g/mol
type: SIO_000074

gram per milliliter
notation: g/ml
type: SIO_000074

Perfluoro-n-pentanoic acid
notation: PFPeA
subclass of: PFC
type: Class

millimole
notation: mmol
type: SIO_000074

nanogram per gram
notation: ng/g
type: SIO_000074

Several times a month exposure to second hand smoke from E-cigarettes
notation: 257
subclass of: environmental e-cigarette smoke exposure
type: Class
type: QualityValue

Bedroom Dust
subclass of: Allergen
subclass of: ENVO_00002008
type: Class

Detectable
subclass of: SIO_001167
type: Class

Fibrinogen Assay (Clauss method)
subclass of: SIO_001007
type: Class

Mass Spectrometer
definition: Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. In simpler terms, a mass spectrum measures the masses within a sample. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

kilogram per mole
notation: kg/mol
type: SIO_000074

9-hydroxyphenanthrene
notation: PHEN9
subclass of: PAH
type: Class

Blood Eosinophil Count
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

Perfluorohexanoic acid
notation: PFHxA
subclass of: PFC
type: Class

parts per quadrillion
notation: ppq
type: SIO_000074

Uses Iron Supplement
notation: 332
subclass of: nutrition intake
subclass of: Restriction
  some values from: Iron Vitamin Supplement
  on property: SIO_000230
type: Class
type: QualityValue

No Formal Education
notation: 57
definition: Has not been educated in a formal setting.
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Never exposed to second hand smoke
notation: 254
subclass of: environmental tobacco smoke exposure
type: Class
type: QualityValue

Dog Allergen
subclass of: Allergen
type: Class

Lipemic sample, clarified before running
subclass of: SIO_001167
type: Class

gram per liter
notation: g/L
type: SIO_000074

picomole
notation: pmol
type: SIO_000074

Occupation
definition: An individual attribute that is the usual or principal work or business of an individual.
subclass of: SIO_000016
subclass of: Socioeconomic Status
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

birthing
subclass of: Birth Outcome
type: Class

fine respirable suspended particulate matter
subclass of: Air Pollutant
type: Class
type: QualityVariable

Perfluorooctanesulfonic acid
notation: PFOS
definition: Perfluoroalkyls are stable, synthetic chemicals. Perfluoroalkyls are unique because they repel oil, grease, and water. The two perfluoroalkyls made in the largest amounts in the U. S. areperflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Perfluoroalkyls have been used in surface protection products such as carpet and clothing treatments and coating for paper and cardboard packaging. They have also been used in fire-fighting foams.
subclass of: PFC
type: Class

No Insurance / Self-funded
notation: 89
subclass of: Average B6 Supplement Intake
subclass of: Private Insurance or Self Pay
type: Class
type: QualityValue

Folic Acid Vitamin Supplement
subclass of: NCIT C944
subclass of: Restriction
  some values from: CHEBI_27470
  on property: SIO_000313
type: Class

Daily Exposure to Second Hand Smoke from E-cigarettes
notation: 255
subclass of: environmental e-cigarette smoke exposure
type: Class
type: QualityValue

Lipemic and turbid
subclass of: SIO_001167
type: Class

Cat Allergen
subclass of: Allergen
type: Class

blood lymphocyte count
subclass of: SIO_000794
type: Class

3,5,6-trichloropyridine-2-one
definition: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.
subclass of: Metabolite
type: Class

2-hydroxynaphthalene
notation: NAP2
subclass of: PAH
type: Class

kilogram per liter
notation: kg/L
type: SIO_000074

cubic meter per mole
notation: m3/mol
type: SIO_000074

nanomole
notation: nmol
type: SIO_000074

N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
notation: VOCCYM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Annual Income $5,000 or Less
notation: 159
definition: Personal or family annual income at or below $5,000
subclass of: Annual Income $14,999 or Less
subclass of: Household Income
type: Class
type: QualityValue

Several times a month exposure to second hand smoke
notation: 252
subclass of: environmental tobacco smoke exposure
type: Class
type: QualityValue

Competitive-inhibition enzyme-linked immunosorbent assay
subclass of: enzyme-linked immunosorbent assay (ELISA)
type: Class

Has Used Cannabinoids But No Longer
notation: 331
subclass of: Consumption Behavior
type: Class
type: QualityValue

Liquid Chromotography-Mass Spectrometery
subclass of: MassSpectrometry
type: Class

compound eye retinal cell
subclass of: Cell
type: Class

(15Z)-tetracosenoic acid
notation: C241N9
definition: A tetracosenoic acid having a cis-double bond at position 15.
subclass of: Fatty Acid
type: Class

attomole
notation: amol
type: SIO_000074

Annual Income $5,001 to $15,000
notation: 160
definition: Personal or family annual income bwtween $5,001 and $15,000
subclass of: Household Income
type: Class
type: QualityValue

Iron Vitamin Supplement
subclass of: NCIT C944
subclass of: Restriction
  some values from: CHEBI_18248
  on property: SIO_000313
type: Class

Nicotine (total)
notation: NICT
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class

Common Era
definition: Common era time measurements are referenced against (in relation to) the beginning of the common era, 1 CE (or 1 AD).
equivalent class: Restriction
  on property: inRelationTo
  has value: First Year of the Common Era
subclass of: Relative Time
type: Class

Rarely exposed to second hand smoke
notation: 253
subclass of: environmental tobacco smoke exposure
type: Class
type: QualityValue

Liquid Chromotography -tandem mass spectrometry
subclass of: MassSpectrometry
type: Class

Other Gender
notation: 325
subclass of: Gender
type: Class
type: QualityValue

femtomole
notation: fmol
type: SIO_000074

milligram per milliliter
notation: mg/ml
type: SIO_000074

Birth Order
subclass of: Birth Outcome
type: Class
type: QualityVariable

N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
notation: VOCPMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Result repeated with diluted sample
subclass of: SIO_001167
type: Class

2-Chlorophenol
notation: MCP2
definition: 2-chlorophenol is a colorless to amber liquid with an unpleasant, penetrating odor. Density 1.265 g / cm3. Sinks in water and slowly dissolves. Freezing point 7°C (46°F). Boiling point 175°C (347°F).
subclass of: Environmental Phenol
type: Class

Boiler Count
definition: A boiler is an object that heats up water. This attribute quantifies the number of boilers in the home.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Education Grade 3
notation: 115
definition: Finished grade 3
subclass of: Some Elementary School
type: Class
type: QualityValue

Native Hawaiian or Other Pacific Islander
notation: 55
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.
subclass of: Race
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Competitive Immunoassay
subclass of: Immunoassay
type: Class

Colorimetric Assay
subclass of: SIO_001007
type: Class

Education Grade
definition: The highest grade of education achieved
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Boron
notation: B
definition: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.
subclass of: Metal
type: Class

Developmental Disorder of Mental Health
notation: 341
subclass of: Disease
type: Class
type: QualityValue

Zileuton (Zyflo)
subclass of: Asthma Controller Medication
type: Class

PCB28
notation: PCB28
subclass of: Polychlorobiphenyl
type: Class

Female Gender
notation: 324
subclass of: Gender
type: Class
type: QualityValue

Result repeated and confirmed
subclass of: SIO_001167
type: Class

N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
notation: VOCTCV
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Buccal Cell
definition: Cells collected from the inner epithelium of the cheek
subclass of: Cell
type: Class

Color Object Association Test
definition: a reliable and a valid measure of declarative memory for healthy children ages 18-36 months, living in a disadvantaged community
subclass of: Neurocognitive Assessment
type: Class

Cold Vapor Atomic Fluorescence Spectroscopy Instrument
definition: Used in the measurement of trace amounts of volatile heavy metals such as mercury, cold vapour AFS makes use of the unique characteristic of mercury that allows vapour measurement at room temperature.
subclass of: Atomic Fluorescence Spectroscopy Instrument
was approved by: PER-Jim-McCusker
type: Class

Education Grade 5
notation: 117
definition: Finished grade 5
subclass of: Some Middle School
type: Class
type: QualityValue

Elective Caesarian Section
notation: 19
definition: A caesarian section that was chosen by the mother but was not medically necessary.
subclass of: Caesarian Section
type: Class
type: QualityValue

Interleukin-2
notation: IL2
subclass of: Protein
type: Class

Alternaria Allergen
subclass of: Allergen
subclass of: NCIT C119320
type: Class

Master's Degree
notation: 143
definition: The Master's Degree is an award that requires the successful completion of a program of study of at least the full-time equivalent of 1 but not more than two academic years of work beyond the bachelor's degree.
subclass of: Some Postgraduate
subclass of: Higher Education
type: Class
type: QualityValue

N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
notation: VOCBPM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Reverse-Phase Mass Spectrometry Profiling
subclass of: MassSpectrometry
type: Class

Bathroom Count
definition: Total Number of Bathrooms in the Home
subclass of: Room Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Education Grade 1
notation: 113
definition: Finished grade 1
subclass of: Some Elementary School
type: Class
type: QualityValue

Cyclomicrons present
subclass of: SIO_001167
type: Class

Mono-2-(carboxymethyl) hexyl phthalate
notation: MCMHP
subclass of: Phthalate
type: Class

square meter
notation: m2
type: SIO_000074

Montelukast (Singulair)
subclass of: Asthma Controller Medication
type: Class

Cockroach Allergen
subclass of: Allergen
type: Class

Hair
definition: A filament, mostly protein, that grows from follicles found in the dermis[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Hair]
subclass of: Tissue
type: Class

Interleukin-13
notation: IL13
subclass of: Protein
type: Class

Result reported based on fewer replicates than required
subclass of: SIO_001167
type: Class

N-Acetyl-S-(phenyl)-L-cysteine
notation: PMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Bedroom Count
definition: Total Number of Bedrooms in the Home
subclass of: Room Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Conceiving
subclass of: SIO_000587
comment: to become pregnant with a child.
type: Class

Education Grade 2
notation: 114
definition: Finished grade 2
subclass of: Some Elementary School
type: Class
type: QualityValue

cigarettes per day
notation: 152
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityValue

platelet count
subclass of: SIO_000794
type: Class

Endotoxin Allergen
subclass of: Allergen
subclass of: NCIT C50918
type: Class

Benzyl paraben
notation: BzPB
definition: Benzylparaben is a Standardized Chemical Allergen. The physiologic effect of benzylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of benzylparaben is Allergens.
subclass of: Paraben
type: Class

Collection Date of Sample
definition: Collection Date of Sample
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Atomic Emission Spectroscopy
subclass of: Atomic Spectroscopy
type: Class

N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
notation: VOCBMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Apgar Score
definition: A method to quickly summarize the health of newborn children. The Apgar score was invented by Virginia Apgar in 1952 when Apgar was an anesthesiologist who developed the score in order to ascertain the effects of obstetric anesthesia on babies. The Apgar scale is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10. The five criteria are summarized using words chosen to form a backronym (Appearance, Pulse, Grimace, Activity, Respiration).
subclass of: SIO_001112
subclass of: Birth Outcome
subclass of: Restriction
  on property: hasValue
  all values from: Datatype
    intersection of: Datatype
      with restrictions:
        min inclusive: 0
      on datatype: integer
    intersection of: Datatype
      with restrictions:
        max inclusive: 10
      on datatype: integer
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

square millimeter
notation: mm2
type: SIO_000074

Aspergillus Allergen
subclass of: Allergen
subclass of: NCIT C77180
type: Class

Chromatography Instrument
definition: Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

Atomic Absorption Spectroscopy
subclass of: Atomic Spectroscopy
type: Class

Kaufman ABC Sequence Subscale
definition: Subscale of Kaufman ABC designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas
subclass of: Neurocognitive Assessment
type: Class

N-Acetyl-S-(n-propyl)-L-cysteine
notation: BPMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Arsenic Species
definition: A molecular entity with arsenic components.
subclass of: Targeted Analyte
type: Class

Conception
definition: When a sperm fertilizes an egg
subclass of: SIO_000417
subclass of: From Conception
subclass of: Beginning
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

8-isoprostane
subclass of: Biomolecule
subclass of: Biological Response
type: Class

white blood cell count
subclass of: SIO_000794
type: Class

square centimeter
notation: cm2
type: SIO_000074

Segmented Neutrophil Percentage
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

FEF 25-75 Best Value
definition: The best FEF 25-75 value achieved by a subject during a series of FEF 25-75 measurements.
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

Blinded Season 4 Group
notation: 301
subclass of: Seasonal Population Group
type: Class
type: QualityValue

all-cis-5, 8, 11, 14, 17-icosapentaenoic acid
notation: C205N3
definition: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.
subclass of: Fatty Acid
type: Class

Interleukin-12 subunit alpha
notation: IL12P70
subclass of: Protein
type: Class

Collision-Induced Dissociation (CID)
subclass of: TandemMassSpectrometry
type: Class

Biospecimen
definition: A biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are stored, ideally they remain equivalent to freshly-collected specimens for the purposes of research.
subclass of: SIO_010412
type: Class

native cell
subclass of: Cell
type: Class

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
notation: AMCC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

gram per cubic centimeter
notation: g/cm3
type: SIO_000074

GO_0016265
deprecated: true

Nitric Oxide
subclass of: Air Pollutant
type: Class

Allergen
subclass of: Environmental Exposure
subclass of: NCIT C62651
subclass of: CHEBI_50904
type: Class

mono ethyl hexyl phthalate
notation: MEHP
definition: PHYSICAL DESCRIPTION: Clear colorless to cloudy white viscous liquid. (NTP, 1992)
subclass of: Phthalate
type: Class

College Graduate
notation: 12
definition: The quality of having graduated from College
subclass of: Educational Status
subclass of: Higher Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Before
definition: A negative index of a time measurement in relation to a reference event. A conventional time measurement can be generated from a before time measurement by duplicating the measurement, reversing the sign of the value, and removing the "Before" class.
subclass of: Relative Time
type: Class

N-Acetyl-S-(benzyl)-L-cysteine
notation: BMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Alkyl Phosphate Pesticide Metabolite
subclass of: Targeted Analyte
type: Class

kilogram per cubic meter
notation: kg/m3
type: SIO_000074

red blood cell count
subclass of: SIO_000794
type: Class

Carbon Tetrachloride
notation: CTET
definition: CARBON TETRACHLORIDE is a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
subclass of: Volatile Organic Compound
type: Class

Blood Segmented Neurophil Count
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

4, 4'-DDT
notation: PPDDT
subclass of: Organochlorine Compound
type: Class

Mandelic acid
notation: MA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Did Not Consume Alcohol
notation: 53
subclass of: Alcohol Use
type: Class
type: QualityValue

Hemoglobin Genotype AA
type: QualityValue
notation: 348
disjoint with: Class
  some valuesfrom: NCIT C131682
  on property: RO_0003303
disjoint with: Class
  some values from: SCDO_0000514
  on property: SCDO_1000222
IAO_0000115: A genotype whereby both HBB alleles produce hemoglobin beta chains for normal adult hemoglobin. Individuals with this genotype are not carriers of the sickle cell trait.
has exact synonym: Hemoglobin Genotype AA
subclass of: SCD Genotype
type: Class
subclass of: Genotype
has exact synonym: Haemoglobin Genotype AA
subclass of: Class
  some values from: SCDO_0004139
  on property: SCDO_1000222
has exact synonym: AA Genotype
has exact synonym: AA Hemoglobin Genotype
has exact synonym: Hemoglobin A Genotype

mono-carboxy isononyl phthalate
notation: mCINP
subclass of: Phthalate
type: Class

Asthma Induced Night Sleeplessness
subclass of: Physical And Mental Assessment
subclass of: HP_0002360
subclass of: GO_0048266
subclass of: Restriction
  some values from: wheezing or tightness in the chest or cough
  on property: SIO_001157
type: Class
type: QuantityVariable

Less than High School
notation: 215
subclass of: Educational Status
subclass of: High School or Less
type: Class
type: QualityValue

Tibia
definition: The major preaxial endochondral bone in the posterior zeugopod.
subclass of: SIO_010046
type: Class

Unknown Race
notation: 48
definition: Unknown Race
subclass of: Race
type: Class
type: QualityValue

Aluminum
notation: Al
definition: ALUMINUM is a metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
subclass of: Metal
type: Class

Selenium
notation: Se
definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
subclass of: Metal
type: Class

Phenanthrene tetrol
notation: PHET

Screening
definition: The time period during which a screening process is used to determine the inclusion of a subject in a study.
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
type: Class

Sickle Cell Anemia
notation: 122
definition: A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
subclass of: SIO_010299
subclass of: Health Outcome
type: Class
type: QualityValue

SIO_000982
notation: 106
type: QualityValue

Mandelic acid(ng/mL)
notation: VOCMAD
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Black Non-Hispanic
notation: 216
subclass of: Non-Hispanic Ethnicity
subclass of: African American
type: Class
type: QualityValue

Diet Quantity
editorial note: What differentiated diet from nutrition? That is why is this needed since we have the DietAndNutrition Class
definition: A quantity relating to diet and nutrition.
subclass of: SIO_000052
subclass of: Diet and Nutrition
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

times per two weeks
notation: times / two weeks
type: SIO_000794
type: SIO_000074

Unmarried
notation: 46
definition: Indicates a person not currently joined in a legally binding matrimonial union.
subclass of: Marital Status
type: Class
type: QualityValue

mono-carboxy isooctyl phthalate
notation: mCIOP
subclass of: Phthalate
type: Class

units per square meter
notation: U/m^2
type: SIO_000074

plaque forming unit
notation: pfu
type: SIO_000074

Mono-2-ethyl-5-oxohexylterephthalate
notation: MEOHTP

Samples Arrived Thawed and Analyzed
subclass of: SIO_001167
type: Class

Population Group
definition: A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender)
subclass of: StudyIndicator
type: Class
type: QualityVariable

Coma
notation: 124
definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli.
subclass of: Phenotype
type: Class
type: QualityValue

Pregnancy
definition: The time during which one or more offspring develops inside a woman.
subclass of: SIO_000417
subclass of: From Conception
subclass of: Pregnancy Characteristic
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

High School or Less
notation: 33
definition: Education Level of High School or Less
subclass of: Educational Status
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

plaque forming unit per milliliter
notation: pfu/ml
type: SIO_000074

Consumed Alcohol
notation: 52
subclass of: Alcohol Use
type: Class
type: QualityValue

mono-2-heptyl phthalate
notation: mHpP
subclass of: Phthalate
type: Class

Difference of Z-Scores
definition: The arithmetic difference of two Z-Scores
subclass of: Physical And Mental Assessment
subclass of: Difference
subclass of: Restriction
  some values from: Class
    intersection of: Minuend
    intersection of: Z-Score
  on property: SIO hasAttribute
subclass of: Restriction
  some values from: Class
    intersection of: Subtrahend
    intersection of: Z-Score
  on property: SIO hasAttribute
type: Class
type: QualityVariable

drug other than antimalarial
definition: Any drug other than an antimalarial drug
subclass of: drug
subclass of: Class
  intersection of: drug
  intersection of: Class
    complement of: Antimalarial
type: Class

Full Time Employment
notation: 64
definition: Employed for a standard number of hours of working time, at least 50% or 20 hours per week.
subclass of: Occupation
type: Class
type: QualityValue

Gadolinium
notation: Gd
definition: Gadolinium. An element of the rare earth family of metals. GADOLINIUM has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
subclass of: Metal
type: Class

international units per litre
notation: IU/L
type: SIO_000074

Vitamin D
definition: Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body.
subclass of: Biomolecule
subclass of: Diet and Nutrition
type: Class

Apartment
notation: 196
subclass of: NCIT C86029
type: Class
type: QualityValue

Earth
notation: 182
type: QualityValue

Higher Education
notation: 31
definition: College or university education beyond the successful completion of high school or grammar school, or the attainment of an approved equivalent
subclass of: Educational Status
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Date of Birth
definition: Date of day on which a person was born.
subclass of: SIO_000417
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

White Non-Hispanic
notation: 214
subclass of: Non-Hispanic Ethnicity
subclass of: ExO_0000158
type: Class
type: QualityValue

Received Drug Therapy
subclass of: SIO_001398
subclass of: Pharmacotherapy
subclass of: Restriction
  some values from: drug
  on property: SIO_000230
type: Class

mono-benzyl phthalate
notation: mBzP
editorial note: Is this a repeat of MBP?
subclass of: Phthalate
type: Class

colony forming unit per milliliter
notation: cfu/ml
type: SIO_000074

Asthma Induced Reduced Play Or Activity
subclass of: Physical And Mental Assessment
subclass of: HP_0000721
subclass of: GO_0048266
subclass of: Restriction
  some values from: wheezing or tightness in the chest or cough
  on property: SIO_001157
type: Class
type: QuantityVariable

billion parts per microgram
notation: x109 µL
type: SIO_000074

Urination
subclass of: Targeted Analyte
subclass of: Biological Response
type: Class
type: QualityVariable

Bisphenol S
notation: BPS
subclass of: Environmental Phenol
type: Class

Never Smoked
notation: 56
definition: The quality of never smoking in the past.
subclass of: Smoking Status
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Cement Floor
notation: 10
definition: Cement Floor Type
subclass of: Floor Type
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Elementary School
notation: 15
definition: Finished Elementary School
subclass of: Educational Status
subclass of: Some Elementary School
was approved by: PER-Jim-McCusker
type: Class
type: QualityValue

Fresh Vegetable Consumption
notation: 29
definition: Whether or not Fresh Vegetables are consumed.
subclass of: Fresh Vegetable Consumption Frequency
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Body Weight Quality
definition: A categorization of body mass relative to the height, as defined using Body Mass Index.
subclass of: SIO_000005
subclass of: Anthropometry
type: Class

10^9 cells per microliter
notation: 10^9 cells / µL
type: SIO_000794
type: SIO_000074

Subtrahend
definition: In a difference expression, the subtrahend is the quantity or number to be subtracted from another.
subclass of: SIO_000052
type: Class
type: QuantityVariable

Iodine
notation: I
definition: Iodine is a nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
subclass of: Element
type: Class

Cyclohexane-1, 2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
notation: MCOCH

Sample frozen
subclass of: SIO_001167
type: Class

microgram per liter
notation: µg/L
type: SIO_000074

Perfluorohexane-1-sulphonic acid
notation: PFHxS
subclass of: PFC
type: Class

Trunk
definition: Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present.
subclass of: SIO_010046
type: Class

Normal Weight
notation: 61
definition: Adult normal weight is defined as having a BMI between 18.5 and 25 kg/m^2; Child normal weight is defined as greater than or equal to the 5th percentile but less than the 85th percentile for age, gender and height.
subclass of: Underweight/Normal
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

disintegrations per second
notation: dps
type: SIO_000074

Gestational Age at Birth
definition: Describes how far along a pregnancy is, usually measured in weeks, as measured at birth.
equivalent class: Class
  intersection of: Gestational Age
  intersection of: Restriction
    on property: measuredAt
    all values from: Birth
subclass of: Gestational Age
type: Class

Minuend
definition: In a difference expression, the minuend is the quantity or number from which another is to be subtracted.
subclass of: SIO_000052
type: Class
type: QuantityVariable

Car Count
editorial note: Again, this isn't related to physical properties of housing. This is more closely related to Socioeconomic Status. Consider moving it.
definition: Total Number of Cars in the Home
subclass of: SIO_000794
subclass of: Housing Characteristic
type: Class
type: QuantityVariable

6-chloronicotinic acid
notation: CINA6

Vanadium
notation: V
definition: A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.
subclass of: Metal
type: Class

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2PHEN3

Run out-of-contol; insufficient sample for repeat analysis
subclass of: SIO_001167
type: Class

mono-(2-ethyl-5-carboxypentyl) phthalate
notation: mECPP
editorial note: Duplicate of MCEPP?
subclass of: Phthalate
type: Class

mono (2-ethyl-5-oxohexyl) phthalate
notation: MEOHP
subclass of: Phthalate
type: Class

parasites per microliter
notation: parasites / µL
type: SIO_000794
type: SIO_000074

Delivery Characteristics
definition: Attributes related to the delivery of a child.
subclass of: StudyIndicator
type: Class

C-reactive protein
definition: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
subclass of: Protein
type: Class

alpha-linolenic acid
notation: C183N3
definition: A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.
subclass of: Fatty Acid
type: Class

Uranium
notation: U
definition: Uranium. A radioactive element of the actinide series of metals. URANIUM has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
subclass of: Metal
type: Class

Concentration
subclass of: Laboratory Result
type: Class
type: QuantityVariable

Fluticasone/vilanterol (Breo Ellipta)
subclass of: Asthma Controller Medication
type: Class

Asian
notation: 6
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
subclass of: Race
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
type: Class

Caesarian Section
notation: 20
definition: Caesarian Section Medical Procedure. One-third of pregnancies in the US end in C-Sections.
subclass of: Route Of Delivery
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

Education Grade 6
notation: 118
definition: Finished grade 6
subclass of: Some Middle School
type: Class
type: QualityValue

Fast Food Consumption
notation: 16
definition: Whether or not fast food is consumed.
subclass of: Fast Food Consumption Frequency
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

milligrams-microunits per deciliter-milliliter
notation: (mg/dL)*(µU/mL)
type: SIO_000074

Indoor Air
subclass of: ENVO_00002005
subclass of: Restriction
  some values from: ExO_0000019
  on property: SIO_000128
type: Class

Sample older than 2 weeks
subclass of: SIO_001167
type: Class

Budesonide DPI (Pulmicort)
subclass of: Asthma Controller Medication
type: Class

Gender
subclass of: Demographic
type: Class
type: QualityVariable

Canned Food Consumption Frequency
editorial note: Also want to list this under Environmental Exposures (b/c canned food has chemicals in the lining so sometimes it is used as a proxy)
definition: Frequency of Canned Food Consumption.
subclass of: Diet Quantity
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Cadmium
notation: Cd
definition: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.
subclass of: Metal
type: Class

volt
notation: Volt
type: SIO_000074

First Trimester
definition: From pregnancy week 1 through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the embryo and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).
subclass of: SIO_000417
subclass of: From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

Beclomethasone HFA
subclass of: Asthma Controller Medication
type: Class

Education Grade 7
notation: 119
definition: Finished grade 7
subclass of: Some Middle School
type: Class
type: QualityValue

Outdoor Air
subclass of: ENVO_00002005
subclass of: Restriction
  some values from: ExO_0000020
  on property: SIO_000128
type: Class

Bodily Fluid
definition: Liquids originating from inside the bodies of living people. They include fluids that are excreted or secreted from the body, and body water that normally is not.
subclass of: Biospecimen
type: Class

Cyclohexane-1, 2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
notation: MHNCH

Sample integrity/quality compromised preventing analysis
subclass of: SIO_001167
type: Class

Arsenic
notation: As
definition: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
subclass of: Metal
type: Class

Cord Blood
definition: Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Cord_blood]
subclass of: Pregnancy Sample
subclass of: Whole Blood
type: Class

Hemoglobin Genotype AS
notation: 347
subclass of: Genotype
subclass of: SCD Genotype
type: Class
type: QualityValue

Physical Activity
subclass of: Physical Activity and Fitness
type: Class
type: QuantityVariable

mono(7-carboxyheptyl)phthalate
notation: mCHpP
subclass of: Phthalate
type: Class

Stress Frequency
editorial note: Again, we might want to link this to a specific assessment?
definition: How frequently a person gets stressed.
subclass of: SIO_000475
subclass of: Mental Health
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

ADOS calibrated severity score
definition: Calibrated severity score on the Total Standardized Autism Diagnostic Observation Schedule (ADOS).
subclass of: CAO_01168
type: Class
type: QuantityVariable

Overweight (BMI 25-29.9) and no hypertensive disorder and no diabetes
notation: 328
subclass of: Overweight BMI
subclass of: Class
  intersection of: Overweight BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: Class
type: QualityValue

Used to take asthma control medications but no longer
notation: 276
subclass of: Has taken asthma control medications
subclass of: Asthma Controller Use
subclass of: Restriction
  some values from: Used to take but no longer
  on property: SIO_000217
type: Class
type: QualityValue

Fluticasone furoate DPI (Arnuity Ellipta)
subclass of: Asthma Controller Medication
type: Class

second
notation: s
type: SIO_000074

Airborne Particulate Matter
subclass of: Air Pollutant
type: Class
type: QualityVariable

Meconium
definition: A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth. [database_cross_reference: BTO:0000838]
subclass of: Pregnancy Sample
subclass of: Feces
type: Class

nanogray
notation: nGy
type: SIO_000074

Inorganic Mercury (Hg2+)
notation: Hg2
subclass of: Mercury Species
type: Class

Cis-Nonachlor
notation: CNON
subclass of: Organochlorine Compound
type: Class

Takes asthma control medications some days but not others
notation: 277
subclass of: Has taken asthma control medications
subclass of: Asthma Controller Use
subclass of: Restriction
  some values from: Takes some days but not others
  on property: SIO_000217
type: Class
type: QualityValue

Toaster Count
definition: Number of appliances used to toast bread.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

diabetes mellitus
notation: 342
subclass of: Health Outcome
type: Class
type: QualityValue

Dead
notation: 173
definition: The cessation of life.
subclass of: Destination
type: Class
type: QualityValue

Obese (BMI >30) and no hypertensive disorder and no diabetes
notation: 329
subclass of: Obese BMI
subclass of: Class
  intersection of: Obese BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: Class
type: QualityValue

Prenatal Vitamin Use
notation: 149
definition: Prenatal vitamins are supplements that contain daily vitamins and minerals needed by mothers before and during pregnancy.
subclass of: MAXO_00001018
type: Class
type: QualityValue

Pacific Islander or Native Hawaiian, non-Hispanic
notation: 242
subclass of: Non-Hispanic Ethnicity
subclass of: Native Hawaiian or Other Pacific Islander
type: Class
type: QualityValue

milligray
notation: mGy
type: SIO_000074

nanogram per milliliter
notation: ng/ml
type: SIO_000074

Serum
definition: Liquid derived from blood plasma that has clotting factors removed. [database_cross_reference: http://en.wikipedia.org/wiki/Serum_(blood)][database_cross_reference: http://orcid.org/0000-0002-6601-2165]
subclass of: Blood Component
type: Class

Unemployment
notation: 67
definition: The state of not having a job.
subclass of: Occupation
type: Class
type: QualityValue

PCB52
notation: PCB52
subclass of: Polychlorobiphenyl
type: Class

Bisulfite Pyrosequencing
subclass of: Nucleic Acid Sequencing
type: Class

Housing Characteristic
definition: Housing Characteristic Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Never takes asthma control medications
notation: 274
subclass of: Asthma Controller Use
subclass of: Restriction
  some values from: Never takes
  on property: SIO_000217
type: Class
type: QualityValue

Soil Floor
notation: 84
definition: The flooring is made of soil.
subclass of: Floor Type
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Pentachlorophenol
notation: PCP
definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
subclass of: Environmental Phenol
type: Class

mono (6-COOH-2-methylheptyl) phthalate
notation: MCOMHP
subclass of: Phthalate
type: Class

Non-White
notation: 149
definition: A race other than white.
subclass of: Race
type: Class
type: QualityValue

Educational Status
subclass of: SIO_001326
subclass of: OMIT_0005773
subclass of: Education
type: Class
type: QualityVariable

Any hypertensive disorder or any diabetes, any BMI
notation: 330
union of: hypertension
union of: diabetes mellitus
subclass of: Health Outcome
type: Class
type: QualityValue

millicurie
notation: mCi
type: SIO_000074

kilovolt-hour
notation: kVh
type: SIO_000074

Seizures
notation: 125
definition: Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.
subclass of: Phenotype
type: Class
type: QualityValue

kelvin
notation: K
type: SIO_000074

Part Time Employment
notation: 65
definition: Employment involving less than the standard or customary working time.
subclass of: Occupation
type: Class
type: QualityValue

Interleukin-21
notation: IL21
subclass of: Protein
type: Class

mono (7-COOH-2-methyloctyl) phthalate
notation: MCOMOP
subclass of: Phthalate
type: Class

Steroid Treatment form of Medical Therapy
notation: 28
definition: Had a form of treatment which uses steroids.
subclass of: Medical Therapy Procedure
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

10^6 cells per microliter
notation: 10^6 cells / µL
type: SIO_000794
type: SIO_000074

Only takes asthma control medications with symptoms
notation: 275
subclass of: Has taken asthma control medications
subclass of: Asthma Controller Use
subclass of: Restriction
  some values from: Only takes with symptoms
  on property: SIO_000217
type: Class
type: QualityValue

Social Affect + Restricted and Repetitive Behavior Total
definition: Total Standardized Autism Diagnostic Observation Schedule (ADOS) score.
subclass of: CAO_01168
type: Class
type: QuantityVariable

Healthy (BMI <25) weight and no hypertensive disorder and no diabetes
notation: 327
subclass of: Healthy BMI
subclass of: Class
  intersection of: Healthy BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: Class
type: QualityValue

Chromium
notation: Cr
definition: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002, 1985), chromium and some of its compounds have been listed as known carcinogens.
subclass of: Metal
type: Class

nanosievert
notation: nSv
type: SIO_000074

ampere
notation: A
type: SIO_000074

Ciclesonide HFA (Alvesco)
subclass of: Asthma Controller Medication
type: Class

Student
notation: 66
subclass of: Educational Status
subclass of: Occupation
type: Class
type: QualityValue

percentile
notation: %
type: SIO_000074

Residential Building
notation: 154
subclass of: Housing Characteristic
type: Class
type: QualityVariable
type: QualityValue

Annual Income $40,001 to $70,000
notation: 207
subclass of: Household Income
type: Class
type: QualityValue

Used Only Anti Malarials or No Medications
notation: 139
subclass of: Drug Other Than Antimalarial Use
subclass of: Prescription Medication and Dietary Supplements
type: Class
type: QualityValue

Received Antimalarial Therapy
notation: 344
subclass of: Antimalarial Use
subclass of: Received Drug Therapy
subclass of: Restriction
  some values from: Antimalarial
  on property: SIO_000230
type: Class
type: QualityValue

SO_0000000
deprecated: true

Small Molecule
definition: A small molecule is a low molecular weight (< 900 daltons) organic compound that may help regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
subclass of: Biomolecule
type: Class

dimethylphosphate
notation: DMP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Home Ownership
definition: Who owns the home they live in.
subclass of: Demographic
type: Class
type: QuantityVariable

Takes some days but not others
subclass of: SIO_001290
type: Class

candela
notation: cd
type: SIO_000074

Disease
subclass of: SIO_010299
subclass of: Health Outcome
type: Class

disintegrations per minute
notation: dpm
type: SIO_000074

Cromolyn
subclass of: Asthma Controller Medication
type: Class

SIO_000554
notation: 134
type: QualityValue

Insulin
definition: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.
subclass of: Protein
subclass of: Metabolite
type: Class

3-phenoxybenzoic acid
definition: A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides.
subclass of: Metabolite
type: Class

Biomolecule
definition: A biospecimen that is composed of molecular entities.
subclass of: Biospecimen
type: Class

Received Drug Therapy Other Than Antimalarials
notation: 345
subclass of: Drug Other Than Antimalarial Use
subclass of: Received Drug Therapy
subclass of: Restriction
  some values from: drug other than antimalarial
  on property: SIO_000230
type: Class
type: QualityValue

dimethylthiophosphate
notation: DMTP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Annual Income More Than $70,001
notation: 208
subclass of: Household Income
type: Class
type: QualityValue

Takes every day
subclass of: SIO_001292
type: Class

Smoker
notation: 105
definition: The quality of smoking cigarettes.
subclass of: Smoking Status
type: Class
type: QualityValue

Renter
notation: 148
definition: This person rents the home they live in.
subclass of: Home Ownership
type: Class
type: QualityValue

microcurie
notation: µCi
type: SIO_000074

mole
notation: mol
type: SIO_000074

milliunits per milliliter
notation: mU/ml
type: SIO_000074

Dimethylarsinic Acid
notation: Dimethylarsinic Acid
subclass of: Arsenic Species
type: Class

Employment
notation: 245
subclass of: Occupation
type: Class
type: QualityValue

Perfluorooctanesulfonamide
notation: PFOSA
subclass of: PFC
type: Class

type 2 diabetes mellitus
notation: 181
subclass of: diabetes mellitus
type: Class
type: QualityValue

Asthma Related Clinic Visit
subclass of: Healthcare Access
subclass of: NCIT C142427
subclass of: Restriction
  some values from: asthma
  on property: SIO_000635
type: Class
type: QuantityVariable

Cotinine (total)
notation: COTT
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class

Tobacco Smoke Exposure
notation: 98
subclass of: Environmental Exposure
type: Class
type: QualityValue

Annual Income $10,001 to $20,000
notation: 205
subclass of: Household Income
type: Class
type: QualityValue

Only takes with symptoms
subclass of: SIO_001290
type: Class

Interleukin-5
notation: IL5
subclass of: Protein
type: Class

diethylthiophosphate
notation: DETP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Relative
definition: Broadly, kinship patterns may be considered to include people related by both descent – i.e. social relations during development – and by marriage. Human kinship relations through marriage are commonly called "affinity" in contrast to the relationships that arise in one's group of origin, which may be called one's descent group. In some cultures, kinship relationships may be considered to extend out to people an individual has economic or political relationships with, or other forms of social connections. Within a culture, some descent groups may be considered to lead back to gods or animal ancestors (totems). This may be conceived of on a more or less literal basis.
subclass of: SIO_000016
subclass of: Demographic
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Relative
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class

micrometer
notation: µm
type: SIO_000074

Vineland Testing
definition: The time period when the Vineland early childhood development testing is administered to a subject.
subclass of: Childhood Followup
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

RNA
subclass of: Macromolecule
type: Class

kilobyte
notation: kB
type: SIO_000074

microliter
notation: µl
type: SIO_000074

millimeter
notation: mm
type: SIO_000074

Interleukin-4
notation: IL4
subclass of: Protein
type: Class

PAH
subclass of: Volatile Organic Compound
type: Class

tetracosanoic acid
notation: C240
definition: A C24 straight-chain saturated fatty acid.
subclass of: Fatty Acid
type: Class

Cousin
notation: 354
definition: A person belonging to the same extended family.
subclass of: SIO_000287
subclass of: Relative
type: Class
type: QualityValue

Tri-Cell DMA-80 Direct Mercury Analyzer
definition: The DMA-80 is based on the principles of sample thermal decomposition, mercury amalgamation and atomic absorption detection. The DMA-80 has been used to develop the US EPA method 7473 (Mercury in solids and solutions by thermal decomposition, amalgamation, and atomic absorption spectrophotometry). It is furthermore compliant with ASTM method D-6722-01 (Total mercury in coal and coal combustion residues) and ASTM method D-7623-10 (Total mercury in crude oil).
subclass of: Direct Mercury Analyzer
was approved by: PER-Jim-McCusker
type: Class

dimethyldithiophosphate
notation: DMDP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

C-C motif chemokine 20
notation: MIP3A
subclass of: Protein
type: Class

Annual Income $20,001 to $40,000
notation: 206
subclass of: Household Income
type: Class
type: QualityValue

Severe Malarial Anemia
notation: 127
definition: In holoendemic transmission areas, Severe Malarial Anemia (SMA) is the primary clinical manifestation of severe childhood malaria, with cerebral malaria occurring only in rare cases. Mortality rates from SMA can exceed 30% in pediatric populations residing in holoendemic transmission areas. The pathophysiological processes that contribute to SMA involve direct and indirect destruction of parasitized and non-parasitized red blood cells (RBCs), inefficient and/or suppression of erythropoiesis, and dyserythropoiesis.
subclass of: Anemia
type: Class
type: QualityValue

Mullens Testing
definition: The time period when the Mullens early childhood development testing is administered to a subject.
subclass of: Childhood Followup
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

Used to take but no longer
subclass of: SIO_001288
type: Class

byte
notation: Byte
type: SIO_000074

counts per minute
notation: cpm
type: SIO_000074

centimeter
notation: cm
type: SIO_000074

cubic decimeter
notation: dm3
type: SIO_000074

Ethyl paraben
notation: EtPB
definition: Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of ethylparaben is Allergens.
subclass of: Paraben
type: Class

Composite Score
definition: A single value that is calculated from multiple scores. This composite score can then be used as a single variable in further analysis and comparison. [def-source: NCI]
subclass of: Physical And Mental Assessment
subclass of: Score
type: Class
type: QualityVariable

Blinded Season 2 Group
notation: 299
subclass of: Seasonal Population Group
type: Class
type: QualityValue

FEV1 Best Value
definition: The best FEV1 value achieved by a subject during a series of FEV1 measurements.
subclass of: CMO_0000254
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

mono (3-carboxypropyl) phthalate (multiple)
notation: MCPP
subclass of: Phthalate
type: Class

Absorbance Reader
definition: Absorbance readers are used for assays such as ELISA assays, protein and nucleic acid quantification or enzyme activity assays. A light source illuminates the sample using a specific wavelength (selected by an optical filter, or a monochromator), and a light detector located on the other side of the well measures how much of the initial (100%) light is transmitted through the sample: the amount of transmitted light will typically be related to the concentration of the molecule of interest.
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker
type: Class

Interfering substances present
subclass of: SIO_001167
type: Class

Ruthenium
notation: Ru
definition: RUTHENIUM is a hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
subclass of: Metal
type: Class

milliliter
notation: ml
type: SIO_000074

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
notation: HPMMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

FEV1 Predicted Value
definition: The expected or predicted FEV1 value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: CMO_0000254
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

Blinded Season 3 Group
notation: 300
subclass of: Seasonal Population Group
type: Class
type: QualityValue

valid measurement
notation: 351
subclass of: Measurement
subclass of: SIO_001167
type: Class
type: QualityValue

5-iso Prostaglandin F2 alpha-VI
notation: F2AVI
subclass of: Targeted Analyte
type: Class

Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)
subclass of: SIO_001167
type: Class

N-Ethyl Perfluorooctane sulfonamido acetic acid
notation: NETFOSAA

Diagnosis Group
subclass of: Health Outcome
subclass of: Demographic
type: Class
type: QualityVariable

N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
notation: MHBMA3
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

cubic centimeter
notation: cm3
type: SIO_000074

Cerebrospinal fluid
definition: A clear, colorless fluid that is found in the brain and spinal cord.
subclass of: SIO_010046
type: Class

Specific Gravity
editorial note: Why is this here? Maybe it belongs in another list
definition: Specific gravity is the ratio of the density of a substance to the density of a reference substance; equivalently, it is the ratio of the mass of a substance to the mass of a reference substance for the same given volume. Apparent specific gravity is the ratio of the weight of a volume of the substance to the weight of an equal volume of the reference substance. The reference substance is nearly always water at its densest (4°C) for liquids; for gases it is air at room temperature (21°C). Nonetheless, the temperature and pressure must be specified for both the sample and the reference. Pressure is nearly always 1 atm (101.325 kPa). Temperatures for both sample and reference vary from industry to industry.
subclass of: SIO_001018
subclass of: Targeted Analyte
type: Class
type: QuantityVariable

FVC Best Value
definition: The best FVC value achieved by a subject during a series of FVC measurements.
subclass of: CMO_0000251
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

Pre-Pregnancy and Pregnancy Month 1
definition: The time period that begins three months prior to conception and ends at the end of the first month of pregnancy.
subclass of: SIO_000417
type: Class

Childhood Cohort Study
subclass of: CohortStudy
type: Class

Asthma Related Hospitalization
subclass of: Healthcare Access
subclass of: Hospitalization
subclass of: Restriction
  some values from: asthma
  on property: SIO_000635
type: Class
type: QuantityVariable

Assisted Reproductive Therapy
notation: 7
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

Kaufman ABC
definition: culturally fair, cognitive ability test for children
subclass of: Neurocognitive Assessment
type: Class

2, 2'-dihydroxy-methoxybenzophenone
notation: BP8

Household
definition: A household consists of one or more people who live in the same dwelling and also share meals or living accommodation, and may consist of a single family or some other grouping of people. A single dwelling will be considered to contain multiple households if either meals or living space are not shared. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to the fields of economics and inheritance.
subclass of: SIO_001064
subclass of: Housing Characteristic
type: Class

mass density unit
notation: mdu
type: SIO_000074

Smoking Status
subclass of: SIO_001326
type: QualityValue
editorial note: We need to discuss this entire hierarchy.
notation: 197
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history
type: QualityVariable
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
subclass of: ExO_0000038

PM 10
subclass of: Environmental Exposure
type: Class

environmental tobacco smoke exposure
notation: 153
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityValue

FVC Predicted Value
definition: The expected or predicted FVC value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.
subclass of: CMO_0000251
subclass of: Restriction
  on property: hasUnit
  has value: liter
type: Class
type: QualityVariable

Development Quotient
definition: A development quotient is a numerical indicator of a (infant to preschool age) child's growth to maturity across a range of psychosocial competencies.
subclass of: Physical And Mental Assessment
subclass of: NCIT C71610
type: Class
type: QuantityVariable

Blinded Season 1 Group
notation: 298
subclass of: Seasonal Population Group
type: Class
type: QualityValue

Alcohol Use
notation: 83
definition: Uses Alcohol
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityValue

Irregular result, no concentration reported
subclass of: SIO_001167
type: Class

liter
notation: L
type: SIO_000074

kilogram per meter
notation: kg/m
type: SIO_000074

Methyl mercury (CH3Hg+)
notation: CH3Hg
subclass of: Mercury Species
type: Class

mono (2-ethyl-5-hydroxyhexyl) phthalate
notation: MEHHP
subclass of: Phthalate
type: Class

E-Cigarette Use
subclass of: Active Smoker
type: Class
type: QualityVariable

Hemoglobin
definition: The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae), as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.
subclass of: Protein
was approved by: PER-Jim-McCusker
type: Class

Childhood Year 1
definition: The time period of a child that begins at birth and ends after one year
subclass of: Childhood Period
type: Class

environmental e-cigarette smoke exposure
definition: Exposure to secondhand smoke via e-cigarettes
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityVariable

Inductively Coupled Plasma Mass Spectrometry
subclass of: MassSpectrometry
type: Class

area density unit
notation: adu
type: SIO_000074

percent
notation: %
type: SIO_000074

millimetres of mercury
notation: mmHg
type: SIO_000074

Homemaker
notation: 68
definition: A person who manages a home as their main daily activity.
subclass of: Occupation
type: Class
type: QualityValue

Childhood Year 2 and Later
definition: The time period that begins at the beginning of a child's second year and ends at the end of childhood.
subclass of: Childhood Period
type: Class

E-Cigarette Puffs Per Day
subclass of: SIO_000794
subclass of: E-Cigarette Use
type: Class
type: QuantityVariable

Asthma Severity Index Composite Score (CASI)
definition: The Composite Asthma Severity Index (CASI) is a comprehensive severity scale combining multiple facets of asthma severity: impairment, risk, and treatment The CASI score, which was developed as a research tool for intervention studies, ranges from 0 to 20 points, with higher scores indicating higher levels of severity, and includes 5 domains: day symptoms and albuterol use, night symptoms and albuterol use, controller treatment, lung function measures, and exacerbations. (Source: Minimally Important Differences and Risk Levels for the Composite Asthma Severity Index Rebecca Z. Krouse, et al.)
subclass of: Health Outcome
subclass of: Physical And Mental Assessment
subclass of: Composite Score
subclass of: NCIT C119810
type: Class
type: QualityVariable

Interleukin-23 subunit alpha
notation: IL23
subclass of: Protein
type: Class

Icteric
subclass of: SIO_001167
type: Class

Matched Pair of Subjects
definition: A set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria
subclass of: SIO_000616
type: Class

Tooth
definition: Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Tooth_(animal)]
subclass of: Tissue
type: Class

microliters per minute
notation: µL/min
type: SIO_000074

Takes asthma control medications every day
notation: 278
subclass of: Has taken asthma control medications
subclass of: Asthma Controller Use
subclass of: Restriction
  some values from: Takes every day
  on property: SIO_000217
type: Class
type: QualityValue

Tobacco Metabolite
subclass of: Targeted Analyte
type: Class

Age Equivalent
definition: Age Equivalent is the individual's ability; skill, knowledge, or measurement expressed as the age at which most individuals reach the same level (age norm). The Age Norm is the average score of a particular test completed by children of a given chronological age.
subclass of: Physical And Mental Assessment
subclass of: Score
type: Class
type: QuantityVariable

cigarettes per day
notation: cigs / day
type: SIO_000074

Initial concentration higher than the highest standard
subclass of: SIO_001167
type: Class

Uses Cannabinoids
notation: 330
subclass of: Consumption Behavior
subclass of: Restriction
  some values from: CHEBI_67194
  on property: SIO_000230
type: Class
type: QualityValue

2, 2'-bis(4-hydroxyphenyl)butane
notation: BPB

count unit
notation: count
type: SIO_000074

cis-vaccenic acid
notation: C181N7
definition: The cis isomer of vaccenic acid.
subclass of: Fatty Acid
type: Class

microgray
notation: µGy
type: SIO_000074

microgram per milliliter
notation: µg/ml
type: SIO_000074

Obese
notation: 63
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

Ultra High Performance Liquid Chromatography Instrument
definition: Modern HPLC systems have been improved to work at much higher pressures, and therefore are able to use much smaller particle sizes in the columns (<2 μm). These "Ultra High Performance Liquid Chromatography" systems or UHPLCs can work at up to 120 MPa (17, 405 lbf/in^2), or about 1200 atmospheres.
subclass of: High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker
type: Class

2-hydroxychrysene
notation: CHRY2
subclass of: PAH
type: Class

Metalloproteinase inhibitor 1
notation: TIMP1
subclass of: Protein
type: Class

Mean Concentration
definition: The mean aggregate of multiple concentration measurements of a single substance within a compound substance.
subclass of: SIO_001109
subclass of: Concentration
type: Class
type: QuantityVariable

Human Dwelling
definition: Any enclosed space that may be considered a human residence, considered broadly. Positive examples include Moble Homes, Single Family Homes, Apartment Buildings, Cars, Garages, Campgrounds, etc.
subclass of: Housing Characteristic
type: Class
type: QualityVariable

Pre-Pregnancy and Pregnancy
definition: The time period that begins three months prior to conception and ends at the birth of a child.
subclass of: SIO_000417
type: Class

Infrared Multiphoton Dissociation (IRMPD)
subclass of: TandemMassSpectrometry
type: Class

4-Chlorophenol
notation: MCP4
definition: P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.
subclass of: Environmental Phenol
type: Class

milligram per liter
notation: mg/L
type: SIO_000074

Nicotine-N-oxide
notation: NICO
subclass of: Tobacco Metabolite
type: Class

Roentgen equivalent man
notation: rem
type: SIO_000074

Overweight
notation: 71
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

formazin nephelometric unit
notation: FNU
type: SIO_000074

Chief Complaint
subclass of: Health Outcome
type: Class
type: QualityVariable

Molybdenum
notation: Mo
definition: MOLYBDENUM is a metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)
subclass of: Metal
type: Class

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
notation: AAMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

active eosinophilic esophagitis
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of more than 25 eosinophils per high-power field area, or 0.158 mm^2 (400x).
type: Class

Biological Response
editorial note: abolic_SDD_v1.xlsx
definition: Indicator of biological response to environmental exposure
subclass of: StudyIndicator
type: Class

thawed and clotted
subclass of: SIO_001167
type: Class

asthma
notation: 193
subclass of: DOID 1176
type: Class
type: QualityValue

PCB180
notation: PCB180
subclass of: Polychlorobiphenyl
type: Class

cubic centimeter per mole
notation: cm3/mol
type: SIO_000074

Interleukin-17A
notation: IL17A
subclass of: Protein
type: Class

Fatty Acid
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
subclass of: Targeted Analyte
type: Class

Interleukin-8
notation: IL8
subclass of: Biological Response
type: Class

N-Acetyl-S-(2-cyanoethyl)-L-cysteine
notation: CYMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Below LOD, results repeated and confirmed (37, 33)
subclass of: SIO_001167
type: Class

eosinophilic esophagitis in remission
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of less than 15 eosinophils per high-power field area, or 0.158 mm^2 (400x).
type: Class

Preschool
notation: 112
definition: Finished preschool
subclass of: Educational Status
subclass of: Education Grade
type: Class
type: QualityValue

quantity of sample insufficient for analysis
subclass of: SIO_001167
type: Class

type 1 diabetes mellitus
notation: 180
subclass of: diabetes mellitus
type: Class
type: QualityValue

Very Poorly Controlled Asthma
notation: 295
subclass of: SIO_001294
subclass of: Health Outcome
subclass of: asthma
type: Class
type: QualityValue

Family history
subclass of: Medical History
type: Class
type: QualityVariable

Perfluoroheptanoic acid
notation: PFHPA
subclass of: PFC
type: Class

Annulled
notation: 43
definition: A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for annullment vary within the presiding jurisdiction, whether geographic or religious.
subclass of: Never Married
type: Class
type: QualityValue

Public Insurance
notation: 79
subclass of: Average B6 Supplement Intake
subclass of: Insurance
type: Class
type: QualityValue

Preschool Child Behavior Checklist
definition: Child Behavior Checklist for ages 1 ½ through 5
subclass of: Neurocognitive Assessment
type: Class

N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
notation: VOCCEM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Targeted Sequencing
definition: Nucleic acid sequencing that limits the scope of sequencing by filtering out portions of the nucleic acids that do not meet some criteria.
subclass of: Nucleic Acid Sequencing
type: Class

Birth Outcome
definition: Birth Outcomes Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

thawed, hemolyzed (covers all three levels) and exposed to light
subclass of: SIO_001167
type: Class

turns per second
notation: 1/s
type: SIO_000074

Arsenic (V) Acid
notation: Arsenic (V) Acid
subclass of: Arsenic Species
type: Class

Benzophenone-1
notation: BP1
subclass of: Benzophenone
type: Class

Interlocutory Marital Status
notation: 44
definition: The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific information is provided to assist in rendering a permanent decision.
subclass of: Marital Status
type: Class
type: QualityValue

Pregnancy Cohort Study
subclass of: CohortStudy
type: Class

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
notation: GAMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
definition: A tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation.
subclass of: Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Birth Cohort Study
subclass of: CohortStudy
type: Class

thawed and hemolyzed (covers all three levels)
subclass of: SIO_001167
type: Class

PCB153
notation: PCB153
subclass of: Polychlorobiphenyl
type: Class

Benzene
notation: BZ
definition: Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
subclass of: Volatile Organic Compound
type: Class

Silver
notation: Ag
definition: Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
subclass of: Metal
type: Class

kilogram meter per second
notation: kg.m/s
type: SIO_000074

Race or Ethnicity Combined
definition: Race or ethinicity as a combined concept.
equivalent class:
  union of: Ethnicity
  union of: Race
subclass of: Demographic
type: Class
type: QualityVariable

2, 2', 4, 4'-tetrahydroxybenzophenone
notation: BP2

Atomic Fluorescence Spectroscopy Instrument
definition: a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

did not precipitate
subclass of: SIO_001167
type: Class

Nickel
notation: Ni
definition: NICKEL is a trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
subclass of: Metal
type: Class

Private Insurance or Self Pay
notation: 51
subclass of: Insurance
type: Class
type: QualityValue

Hemolyzed (covers all three levels), lipemic, and icteric
subclass of: SIO_001167
type: Class

N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
notation: DCVMA22
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Antimony
notation: Sb
definition: ANTIMONY is a metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.
subclass of: Metal
type: Class

meter per second
notation: m/s
type: SIO_000074

2, 5-Dichlorophenol
notation: DCP25
definition: PHYSICAL DESCRIPTION: Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 µg/L at 68-72°F; 33 µg/L at 86°F. Taste threshold 0.5 µg/L. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

Protein
subclass of: Biological Response
type: Class

Visit
definition: The time interval of an encounter between a study subject and a study administrator.
subclass of: SIO_000417
type: Class

Proton Pump Inhibitor Treatment
notation: 27
editorial note: UPDATE: Yes, add the prescription medication, either as an indicator or as a class under Medical Therapy. Whichever works for the ontology. Why isn't this listed under prescription medication? How do you differentiate between medical therapy and prescription medication?
definition: Proton Pump Inhibitor Treatment as a form of medical therapy.
subclass of: Medical Therapy Procedure
type: Class
type: QualityValue

Hemolyzed (covers all three levels) and lipemic
subclass of: SIO_001167
type: Class

N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
notation: DPMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Targeted Analyte
definition: A targeted analyte is one that has been selected by the CHEAR program as a prioritized analyte for CHEAR lab hubs to measure and has been carried over to HHEAR.
subclass of: Analyte
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Cesium
notation: Cs
definition: A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
subclass of: Metal
type: Class

cubic meter per kilogram
notation: m3/kg
type: SIO_000074

Budesonide/formoterol (Symbicort)
subclass of: Asthma Controller Medication
type: Class

No Sickle Cell Anemia
notation: 138
subclass of: Health Outcome
type: Class
type: QualityValue

Born Sixth Or Later
notation: 241
definition: The sixth or later born child
subclass of: Birth Order
subclass of: NCIT C46126
type: Class
type: QualityValue

Behavior Rating Inventory of Executive Function - Preschool Version
definition: Standardized rating scale designed to specifically measure the range of executive function in preschool-aged children
subclass of: Neurocognitive Assessment
type: Class

eosinophils per high-power field
subclass of: SIO_000794
comment: A histological count of the eosinophils in a high-power microscopic field of view, or 0.158 mm^2 (x400).
type: Class

Peripheral Blood Mononuclear Cell
definition: Any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.
subclass of: Cell
type: Class

Retinopathy
notation: 129
definition: Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.
subclass of: Phenotype
type: Class
type: QualityValue

N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
notation: MHBMA1
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

enzyme unit
notation: enzyme unit
type: SIO_000074

cubic meter
notation: m3
type: SIO_000074

First or Second Trimester
definition: The time period from pregnancy week 1 through 28 and includes conception.
subclass of: SIO_000417
subclass of: From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
type: Class

Score
type: Class

Perfluorobutanesulfonic acid
notation: PFBS
subclass of: PFC
type: Class

Atomic Spectroscopy
subclass of: Spectroscopy
type: Class

enzyme-linked immunosorbent assay (ELISA)
definition: ELISA is an immunoassay that uses antibodies and color change to identify a substance (Wikipedia)
subclass of: Immunoassay
type: Class

High Performance Liquid Chromatography
subclass of: Chromatography
type: Class

Previous Smoker
notation: 78
definition: The quality of having smoked in the past.
subclass of: Smoking Status
type: Class
type: QualityValue

N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
notation: PHEMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Trimethylarsine oxide
notation: Trimethylarsine oxide
subclass of: Arsenic Species
type: Class

hematocrit
subclass of: SIO_001018
type: Class

Pharmacotherapy
subclass of: Prescription Medication and Dietary Supplements
type: Class
type: QualityVariable

Cognitive Task
subclass of: Neurocognitive Assessment
type: Class

Phenotype
subclass of: Health Outcome
type: Class

Cis-Chlordane
notation: CCHL
subclass of: Organochlorine Compound
type: Class

Canned Food Consumption
notation: 9
definition: Whether or not canned food is consumed.
subclass of: Canned Food Consumption Frequency
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Ultra Performance Liquid Chromatography - Mass Spectrometer
subclass of: Ultra High Performance Liquid Chromatography Instrument
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

microgram per cubic meter
notation: µg/m3
type: SIO_000074

Fluticasone/salmeterol HFA(Advair HFA)
subclass of: Asthma Controller Medication
type: Class

Tandem Mass Spectrometer
definition: Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages. In a tandem mass spectrometer, ions are formed in the ion source and separated by mass-to-charge ratio in the first stage of mass spectrometry (MS1). Ions of a particular mass-to-charge ratio (precursor ions) are selected and fragment ions (product ions) are created by collision-induced dissociation, ion-molecule reaction, photodissociation, or other process. The resulting ions are then separated and detected in a second stage of mass spectrometry (MS2).
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Month Prior and First Month of Pregnancy
definition: The time period beginning at the beginning of the month prior to conception and ending at the end of the first month of pregnancy
subclass of: SIO_000417
type: Class

Interleukin-10
notation: IL10
definition: Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
subclass of: Protein
type: Class

Leukocyte
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
subclass of: Blood Component
type: Class

CASI Controller Treatment Score
subclass of: Asthma Severity Index Composite Score (CASI)
type: Class
type: QuantityVariable

diethyldithiophosphate
notation: DEDP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Refractometer
definition: A laboratory or field device for the measurement of an index of refraction (refractometry). The index of refraction is calculated from Snell's law while for mixtures, the index of refraction can be calculated from the composition of the material using several mixing rules such as the Gladstone–Dale relation and Lorentz–Lorenz equation.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

Object
subclass of: ScienceIndicator
type: Class

adrenic acid
notation: C224N6
subclass of: Fatty Acid
type: Class

Gestational Age
definition: The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated as the time from the last day of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization
subclass of: Age
subclass of: Birth Outcome
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

beta-hexachlorocyclohexane
notation: BHCH
subclass of: Organochlorine Compound
type: Class

Esophagus
subclass of: SIO_010003
type: Class

Annual Maximum Concentration
subclass of: SIO_001114
subclass of: Concentration
type: Class
type: QuantityVariable

Childhood Period
definition: The age span ranging from birth to adolescence
subclass of: SIO_000417
subclass of: From Birth
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: birthing
type: Class

TermBirth
notation: 97
subclass of: Birth Outcome
type: Class
type: QualityValue

4, 4'-(hexafluoroisopropylidene)-dephenol
notation: BPAF

Early Concerns or High Risk for Autism
notation: 343
subclass of: SIO_010056
type: Class
type: QualityValue

diethylphosphate
notation: DEP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

microsievert
notation: µSv
type: SIO_000074

Annual Income $5,001 to $10,000
notation: 204
subclass of: Annual Income $14,999 or Less
subclass of: Annual Income $5,001 to $15,000
subclass of: Household Income
type: Class
type: QualityValue

Trans-Chlordane
notation: TCHL
subclass of: Organochlorine Compound
type: Class

Never takes
subclass of: SIO_001289
type: Class

California
notation: 185
type: QualityValue

watt-hour
notation: Wh
type: SIO_000074

Blood Component
definition: A derivable component of whole blood.
subclass of: Bodily Fluid
type: Class

Red blood cells present
subclass of: SIO_001167
type: Class

all-cis-icosa-8, 11, 14-trienoic acid
notation: C203N6
definition: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
subclass of: Fatty Acid
type: Class

Urine
definition: Excretion that is the output of a kidney [database_cross_reference: http://en.wikipedia.org/wiki/Urine][database_cross_reference: https://github.com/geneontology/go-ontology/issues/11025]
subclass of: Bodily Fluid
type: Class

Aligent 8800 Triple Quadrupole ICP-MS
subclass of: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

CASI Lung Function Score
subclass of: Asthma Severity Index Composite Score (CASI)
type: Class
type: QuantityVariable

Step
definition: A stepfamily is a family where at least one parent has children that are not genetically related to the other spouse or partner. Either one parent may have children from a previous relationship. Children in a stepfamily may live with one biological parent, or they may live with each biological parent for a period of time. In addition, visitation rights mean that children in stepfamilies often have contact with both biological parents, even if they permanently live with only one. A child is referred to as the stepchild, stepdaughter or stepson of their biological parent's new spouse, and that person as the stepparent, stepfather or stepmother of the child. A stepfather is the husband of one's mother, and not one's biological father. A stepmother is the wife of one's father, and not one's biological mother. A step-grandmother is the wife of one's grandfather, and not one's biological grandmother. A step-grandfather is the husband of one's grandmother, and not one's biological grandfather. Similarly, a stepbrother is the son of a stepparent who one is not biologically related to. A stepsister is the daughter of a stepparent to whom one is not biologically related. A step-grandson is the son of a stepson or stepdaughter who one is not biologically related to. A step-granddaughter is the daughter of a stepson or stepdaughter who one is not biologically related. A parent's spouse of the same sex may also count as a stepparent.
subclass of: Non-Biological Relative
type: Class

Benzophenone-3
notation: BP3
editorial note: Duplicate of OXB?
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
subclass of: Environmental Phenol
type: Class

magnetic flux density unit
notation: MFDU
type: SIO_000074

SpectraMax Plus 384 Microplate Reader
definition: Get absorbance measurements from 190 to 1000 nm quickly for samples in test tubes, cuvettes, and 96- or 384-well microplates. The SpectraMax® Plus 384 Microplate Reader gives you walk-up convenience for both standard spectrophotometer and microplate reader applications on the same instrument. Monochromator wavelength selection saves you the time and trouble of ever having to change out filters. Typical applications for this powerful reader include DNA and RNA quantification, enzyme kinetic assays, and ELISA based assays. When your project is ready for high throughput, take advantage of StakMax® automated microplate handling compatibility for full robotic integration.
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker
type: Class

Annual Mean Concentration
subclass of: Mean Concentration
type: Class
type: QualityVariable

kilogram
notation: kg
type: SIO_000074

Benzophenone
subclass of: Targeted Analyte
type: Class

Fine Motor Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: CAO_03172
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Reproductive Health
definition: Reproductive Health Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

6-hydroxychrysene
notation: CHRY6
subclass of: PAH
type: Class

Technical Post Junior College
notation: 93
definition: Attended a Technical Post Junior College
subclass of: Educational Status
subclass of: Technical School
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

weber
notation: Wb
type: SIO_000074

Biological Relative
definition: Being from the same biological kinship as another person. In that aspect, consanguinity is the quality of being descended from the same ancestor as another person.
subclass of: Relative
type: Class

Subject
definition: A living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information
subclass of: SIO_000016
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Study
was approved by: PER-Jeanette-Stingone
type: Class

Vaginal Birth
notation: 24
editorial note: Again, can we add a delivery class
definition: Had a birthing occur via the vagina.
subclass of: birthing
subclass of: Route Of Delivery
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

meter
notation: m
type: SIO_000074

Adulthood Period
definition: Time period that begins after adolesence and continues until death
subclass of: From Birth
type: Class

CASI Nighttime Asthma Symptoms Score
subclass of: Asthma Severity Index Composite Score (CASI)
type: Class
type: QuantityVariable

Early Learning Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: CAO_01393
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Platinum
notation: Pt
definition: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) PLATINUM is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
subclass of: Metal
type: Class

Replicate Number
definition: Replicate Number
subclass of: SampleIndicator
type: Class

Abnormal nervous system physiology
notation: 352
subclass of: SIO_010056
type: Class
type: QualityValue

(7Z, 10Z, 13Z, 16Z, 19Z)-docosapentaenoic acid
notation: C225N3
definition: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.
subclass of: Fatty Acid
type: Class

Fluticasone/salmeterol DPI (Advair Diskus)
subclass of: Asthma Controller Medication
type: Class

Adult
notation: 3
definition: Refers to a person above a threshold age.
subclass of: Developmental Quality
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Some High School
notation: 87
definition: Education Level of Some High School
subclass of: Educational Status
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

volt-hour
notation: Vh
type: SIO_000074

Tissue
subclass of: Biospecimen
type: Class

Adolescent Period
definition: The age span ranging from adolescence to adulthood
subclass of: SIO_000417
subclass of: From Birth
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: birthing
type: Class

Air Pollutant
subclass of: Environmental Exposure
type: Class
type: QualityVariable

Preschool Child Behavior Checklist Externalizing Subscale
definition: Subscale of preschool CBCL that assesses externalizing behaviors
subclass of: Neurocognitive Assessment
type: Class

CASI Daytime Asthma Symptoms Score
subclass of: Asthma Severity Index Composite Score (CASI)
type: Class
type: QuantityVariable

Tin
notation: Sn
definition: TIN is a trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
subclass of: Metal
type: Class

Broken Mitest
subclass of: SIO_001167
type: Class

Agilent 1100 HPLC
subclass of: High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker
type: Class

Some Middle School
notation: 90
definition: Attended Some Middle School
subclass of: Educational Status
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

CASI Exacerbation Score
subclass of: Asthma Severity Index Composite Score (CASI)
type: Class
type: QuantityVariable

Advanced Graduate Degree
notation: 4
definition: Having earned a pos-baccalaureate degree
subclass of: Education
type: Class
type: QualityValue

tesla
notation: Tesla
type: SIO_000074

Shotgun Lipidomics
subclass of: Electrospray Ionization Mass Spectrometry
type: Class

Preschool Child Behavior Checklist Internalizing Subscale
definition: Subscale of preschool CBCL that assesses internalizing behaviors
subclass of: Neurocognitive Assessment
type: Class

Some College or Technical School
notation: 203
subclass of: Educational Status
subclass of: Higher Education
subclass of: Education
type: Class
type: QualityValue

Blackbody Infrared Radiative Dissociation (BIRD)
subclass of: TandemMassSpectrometry
type: Class

SIO_010048
notation: 111
type: QualityValue

N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
notation: MHBMA2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Mexico
notation: 183
type: QualityValue

mild eosinophilic esophagitis
equivalent class: Restriction
  on property: isPhenotypeOf
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
      on property: hasAttribute
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is mild when a biopsy of the esophagus reveals a count of 15-25 eosinophils per high-power field area, or 0.158 mm^2 (400x).
type: Class

cells per microliter
notation: cp/µl
type: SIO_000074

Not Well Controlled Asthma
notation: 296
subclass of: SIO_001295
subclass of: Health Outcome
subclass of: asthma
type: Class
type: QualityValue

4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
notation: NNAL
editorial note: To Do: align with CHEBI.
subclass of: Tobacco Metabolite
type: Class

Sibling
notation: 353
definition: One of two or more individuals having one or both parents in common. A male sibling is a brother, and a female sibling is a sister. In most societies throughout the world, siblings often grow up together, thereby facilitating the development of strong emotional bonds. The emotional bond between siblings is often complicated and is influenced by factors such as parental treatment, birth order, personality, and personal experiences outside the family. However, there are cases where siblings grow up in separate homes, in different environments.
subclass of: SIO_000287
subclass of: Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Sibling
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Perfluorodecanoic acid
notation: PFDA
subclass of: PFC
type: Class

Quantity of sample insufficient for repeat analysis
subclass of: SIO_001167
type: Class

Nitrogen Dioxide
subclass of: Environmental Exposure
type: Class

monoethyl phthalate (DEP)
notation: MEP
subclass of: Phthalate
type: Class

Cell
subclass of: Biospecimen
type: Class

N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
notation: HPMA2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Active Smoker
notation: 2
editorial note: How is this different from "smoker'?
definition: The quality of actively smoking.
subclass of: Smoking Status
type: Class
type: QualityValue

Some Elementary School
notation: 86
definition: Attended Some Elementary School
subclass of: Educational Status
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Active Non-Tobacco Smoker
notation: 1
definition: Active Non-Tobacco Smoker
subclass of: Active Smoker
type: Class
type: QualityValue

Male Gender
notation: 323
subclass of: Gender
type: Class
type: QualityValue

Prescription Medication and Dietary Supplements
definition: Prescription Medication and Dietary Supplements are forms of medical treatment.
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Well Controlled Asthma
notation: 297
subclass of: SIO_001297
subclass of: Health Outcome
subclass of: asthma
type: Class
type: QualityValue

Cellular debris present
subclass of: SIO_001167
type: Class

Interleukin-27 subunit alpha
notation: IL27
subclass of: Protein
type: Class

Sandwich ELISA
definition: Sandwich ELISAs involve attachment of a capture antibody to a solid phase support. Samples containing known or unknown antigen are then added in a matrix or buffer that will minimize attachment to the solid phase. An enzyme-labeled antibody is then added for detection.
subclass of: enzyme-linked immunosorbent assay (ELISA)
type: Class

Underweight
notation: 99
definition: BMI < 18.5
subclass of: Underweight/Normal
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

Underweight/Normal
notation: 100
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

South Central Clinic
notation: 273
subclass of: Population Group
type: Class
type: QualityValue

Expressive Language Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: CAO_03173
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

gestational diabetes
notation: 179
subclass of: diabetes mellitus
type: Class
type: QualityValue

times per two months
notation: times / two months
type: SIO_000794
type: SIO_000074

Interferon lambda-2
notation: IL28A
subclass of: Protein
type: Class

Bisphenol A
notation: BPA
definition: 4, 4'-isopropylidenediphenol is a white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)
subclass of: Environmental Phenol
type: Class

dots per inch
notation: dpi
type: SIO_000074

watt per square meter
notation: W/m2
type: SIO_000074

Bismuth
notation: Bi
definition: BISMUTH is a metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
subclass of: Metal
type: Class

milligram
notation: mg
type: SIO_000074

Magnesium
notation: Mg
definition: An element with atomic symbol Mg, atomic number 12, and atomic weight 24.3. Magnesium is an alkaline earth metal and is important to bone structure in human physiology.
subclass of: Metal
type: Class

Feces
definition: Portion of semisolid bodily waste discharged through the anus[MW, modified] [database_cross_reference: http://en.wikipedia.org/wiki/Feces][database_cross_reference: http://www.merriam-webster.com/dictionary/feces]
subclass of: Biospecimen
type: Class

Anemia
notation: 128
definition: A reduction in erythrocytes volume or hemoglobin concentration.
subclass of: Phenotype
type: Class
type: QualityValue

UBERON_0036255
deprecated: true

Visual Reception Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: CAO_03171
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Unknown Education Level
notation: 101
definition: Level of Education is not known
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

White Hispanic
notation: 145
definition: White and Hispanic
subclass of: Hispanic or Latino Ethnicity
subclass of: ExO_0000158
type: Class
type: QualityValue

8,12-iso-Isoprostane-F2 alpha-VI
notation: F2A12I
definition: An Isoprostane with the CAS # 1445349-99-4
subclass of: Targeted Analyte
subclass of: CHEBI_138408
type: Class

Mean Body Weight
subclass of: SIO_001109
subclass of: Body Weight Quality
type: Class
type: QuantityVariable

millimolal
notation: mmol/kg
type: SIO_000074

parasite count
subclass of: Concentration
type: Class

3, 4-Dihydroxy benzoic acid
notation: DHB34
subclass of: Environmental Phenol
type: Class

gram
notation: g
type: SIO_000074

Cobalt
notation: Co
definition: COBALT is a trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
subclass of: Metal
type: Class

mono-isononyl phthalate
notation: mINP
subclass of: Phthalate
type: Class

Religion
definition: Religious Belief
subclass of: Demographic
type: Class
type: QualityVariable

Third Trimester
definition: From 29 weeks through 40 weeks.
subclass of: SIO_000417
subclass of: From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

Communication Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: Vineland Communication Domain
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Tobacco Cessation Intervention Group
notation: 202
definition: A group receiving a tobacco cessation intervention that is being tested in a study.
subclass of: Experimental Group
type: Class
type: QualityValue

USC Obstetrics-Gynecology
notation: 271
subclass of: Population Group
type: Class
type: QualityValue

Interstitial collagenase
notation: MMP1
subclass of: Protein
type: Class

Quality Control
definition: The value contains quality control data
subclass of: Analyte
type: Class

nanogram
notation: ng
type: SIO_000074

p-Xylene*
notation: PXY
definition: P-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. Freezing point is 56°F. (USCG, 1999)
subclass of: Volatile Organic Compound
type: Class

pixels per inch
notation: p/in
type: SIO_000074

Limit of Quantitation
definition: The Limit of Quantitation is the lowest concentration at which the analyte can not only be reliably detected but at which some predefined goals for bias and imprecision are met. The LoQ may be equivalent to the LoD or it could be at a much higher concentration. (Source: Limit of Blank, Limit of Detection and Limit of Quantitation, David A Armbruster and Terry Pry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556583/)
subclass of: Concentration
type: Class

Route Of Delivery
subclass of: Delivery Characteristics
type: Class
type: QualityVariable

Total nicotine
notation: TNIC
editorial note: Duplicate of NIC?
subclass of: Tobacco Metabolite
type: Class

Replicate
definition: The value contains data for a repeat of the study sample
subclass of: Analyte
type: Class

Community Recruit
notation: 272
subclass of: Population Group
type: Class
type: QualityValue

Receptive Language Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: CAO_03174
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

einstein per square meter per second
notation: einstein/sm2
type: SIO_000074

micron pixel
notation: µm pixel
type: SIO_000074

microgram
notation: µg
type: SIO_000074

Placenta
definition: Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. [database_cross_reference: http://en.wikipedia.org/wiki/Placenta][database_cross_reference: http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm]
subclass of: Tissue
subclass of: Pregnancy Sample
type: Class

Summer
notation: 212
subclass of: Season
type: Class
type: QualityValue

3-methipurc acd, 4-methipurc acd(ng/mL)
notation: VOC34M
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry
subclass of: Liquid Chromotography-Mass Spectrometery
type: Class

Childhood
notation: 11
definition: A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence.
subclass of: Developmental Quality
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Stress
notation: 92
definition: Whether or not a person gets stressed.
subclass of: Stress Frequency
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Birthplace
definition: The place where a person was born.
subclass of: Location
subclass of: Demographic
type: Class
type: QualityVariable

Lithium
notation: Li
definition: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
subclass of: Metal
type: Class

Childhood Asthma Control Test Score
definition: The Childhood Asthma Control Test is a standardized rating scale developed by Nathan et al in 2004, which is used to identify patients from 4 to 11 years old with poorly controlled asthma. This questionnaire contains seven items, four to be answered with the child patient and three to be answered by the child patient's guardian and the score is computed by summing the responses to the seven items. The CACT Score range is from 0 to 27, where a higher number indicates a better level of asthma control.
subclass of: Health Outcome
subclass of: Physical And Mental Assessment
subclass of: NCIT C25338
type: Class
type: QuantityVariable

LAC + USC Med Center
notation: 269
subclass of: Population Group
type: Class
type: QualityValue

Socialization Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: Vineland Socialization Domain
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

base pair
notation: bp
type: SIO_000074

Antimalarial
notation: 120
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
subclass of: Medication
type: Class
type: QualityValue

femtogram
notation: fg
type: SIO_000074

Pregnancy Characteristic
definition: Pregnancy Characteristic Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

SIO_000784
notation: 109
type: QualityValue

First Year of the Common Era
type: NamedIndividual

Fall
notation: 213
subclass of: Season
type: Class
type: QualityValue

Granulocyte-macrophage colony-stimulating factor
notation: GMCSF
subclass of: Protein
type: Class

3-phenoxybenzoic acid
notation: PBA
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Non-ecigarette user
notation: 199
definition: Doesn't use e-cigarettes.
subclass of: Smoking Status
type: Class
type: QualityValue

Reichert AR200 Handheld Digital Refractometer
definition: Lightweight digital refractometer designed for the food, beverage, agricultural, industrial-fluid, chemical, petrochemical, pharmaceutical, medical, and plastic industries.
subclass of: Refractometer
was approved by: PER-Jim-McCusker
type: Class

Motor Skills Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: Vineland Motor Skills Domain
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Room
notation: 249
subclass of: Human Dwelling
type: Class
type: QualityValue

Technical School
notation: 96
definition: Attended a Technical School.
subclass of: Educational Status
subclass of: Education
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Eisner Health
notation: 270
subclass of: Population Group
type: Class
type: QualityValue

mass-to-charge ratio
notation: Th
type: SIO_000074

picogram
notation: pg
type: SIO_000074

watt per steradian per square meter
notation: W/sr/m2
type: SIO_000074

pixels per millimeter
notation: p/mm
type: SIO_000074

Predominantly fibrous material
subclass of: SIO_001167
type: Class

pascal
notation: Pa
type: SIO_000074

9-hydroxyfluorene
notation: FLUO9
subclass of: PAH
type: Class

Theophylline
subclass of: Asthma Controller Medication
type: Class

Winter
notation: 210
subclass of: Season
type: Class
type: QualityValue

PCB101
notation: PCB101
subclass of: Polychlorobiphenyl
type: Class

Mirex
notation: MIREX
subclass of: Organochlorine Compound
type: Class

PCB138
notation: PCB138
subclass of: Polychlorobiphenyl
type: Class

endotoxin unit per cubic meter
notation: EU/m3
type: SIO_000074

3, 5, 6-trichloro-2-pyridinol
notation: TCP
editorial note: To Do: align with CHEBI.
subclass of: Alkyl Phosphate Pesticide Metabolite
type: Class

Pregnancy Complication
notation: 75
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

microsecond
notation: µs
type: SIO_000074

Second Trimester
definition: From week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided with high-quality medical care.
subclass of: SIO_000417
subclass of: From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

mono-methyl phthalate
notation: mMP
subclass of: Phthalate
type: Class

All Los Angeles RCs plus Orange, San Diego, Tri-counties, and Inland
notation: 340
subclass of: Population Group
type: Class
type: QualityValue

Study Followup
definition: A point in a study where data is gathered after the initial baseline.
subclass of: SIO_000417
type: Class

mebibyte
notation: MiB
type: SIO_000074

gigabyte
notation: GB
type: SIO_000074

Fever
notation: 123
definition: Elevated body temperature due to failed thermoregulation.
subclass of: Phenotype
type: Class
type: QualityValue

Spring
notation: 211
subclass of: Season
type: Class
type: QualityValue

Asthma Control Test Score
definition: The Asthma Control Test is a standardized rating scale developed by Nathan et al in 2004, which is used to identify patients 12 years or older with poorly controlled asthma. This questionnaire contains five items and the score is computed by summing the responses to the five items. The ACT Score range is from 0 to 25, where a higher number indicates a better level of asthma control.
subclass of: Health Outcome
subclass of: Physical And Mental Assessment
subclass of: NCIT C25338
type: Class
type: QuantityVariable

3-Methylhippuric acid + 4-Methylhippuric acid
notation: MHA34
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Birth Year
notation: 198
definition: The year in which a person was born.
subclass of: SIO_000428
type: Class
type: QualityValue

Preterm Birth
notation: 88
definition: Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
subclass of: Birth Outcome
was approved by: PER-Jim-McCusker
type: Class
type: QualityValue

millisecond
notation: ms
type: SIO_000074

Spontaneous Caesarian Section
notation: 22
definition: Had a spontaneous caesarian section
subclass of: Caesarian Section
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

wheezing or tightness in the chest or cough
equivalent class:
  union of: HP_0030828
  union of: HP_0031352
  union of: HP_0012735
subclass of: Physical And Mental Assessment
subclass of: HP_0000118
type: Class
type: QuantityVariable

mono-pentyl phthalate
notation: mPeP
subclass of: Phthalate
type: Class

Daily Living Skills Developmental Quotient
subclass of: Development Quotient
subclass of: Restriction
  some values from: Vineland Daily Living Skills Domain
  on property: wasDerivedFrom
type: Class
type: QuantityVariable

Household Income
definition: A demographic parameter indicating the amount of earnings made by a family.
subclass of: SIO_000052
subclass of: Socioeconomic Status
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

joule
notation: J
type: SIO_000074

kibibyte
notation: KiB
type: SIO_000074

degree Celsius
notation: C
type: SIO_000074

Reactive Airway Disease
notation: 186
definition: Coughing, wheezing, or shortness of breath that is triggered by allergens, infection, or other irritants. [def-source: NCI]
subclass of: NCIT C27557
type: Class
type: QualityValue

gigabasepair
notation: Gb
type: SIO_000074

Nicotine
notation: NIC
definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
subclass of: Tobacco Metabolite
type: Class

Flunisolide HFA (Aerospan)
subclass of: Asthma Controller Medication
type: Class

Ethnicity
subclass of: SIO_000475
subclass of: Race or Ethnicity Combined
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Born Fourth
notation: 239
definition: The fourth born child
subclass of: Birth Order
subclass of: NCIT C54566
type: Class
type: QualityValue

Overweight BMI
subclass of: Health Outcome
subclass of: Body Mass Index
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 25.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 29.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: kilogram per square meter
type: Class
type: QualityValue

4, 4'-(1-phenylethylidene)bisphenol
notation: BPAP

Healthcare Access
definition: Healthcare Access
subclass of: StudyIndicator
type: Class

Tellurium
notation: Te
definition: Tellurium. An element that is a member of the chalcogen family. TELLURIUM has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.
subclass of: Metal
type: Class

PFC
subclass of: Targeted Analyte
type: Class

Polybrominated Diphenyl Ether
subclass of: Targeted Analyte
type: Class

degree Fahrenheit
notation: F
type: SIO_000074

molar
notation: M
type: SIO_000074

Obese BMI
subclass of: Health Outcome
subclass of: Body Mass Index
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 29.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: kilogram per square meter
type: Class
type: QualityValue

Age
subclass of: Demographic
type: Class
type: QuantityVariable

Born Fifth
notation: 240
definition: The fifth born child
subclass of: Birth Order
subclass of: NCIT C54567
type: Class
type: QualityValue

1-hydroxychrysene
notation: CHRY1
subclass of: PAH
type: Class

mono-isobutyl phthalate (DiBP)
notation: MiBP
subclass of: Phthalate
type: Class

HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results
subclass of: SIO_001167
type: Class

Parous
notation: 73
subclass of: Parity
type: Class
type: QualityValue

4-nitrophenol
notation: PNP

SCD Genotype
subclass of: Genotype
type: Class

Non-White Non-Hispanic
notation: 326
subclass of: Non-White
subclass of: Non-Hispanic Ethnicity
type: Class
type: QualityValue

Born Second
notation: 237
definition: The second born child
subclass of: Birth Order
subclass of: NCIT C25666
type: Class
type: QualityValue

Very turbid
subclass of: SIO_001167
type: Class

Hemolyzed (covers all three levels) and debris present
subclass of: SIO_001167
type: Class

Budesonide nebulized (Pulmicort)
subclass of: Asthma Controller Medication
type: Class

liter per kilogram
notation: l/kg
type: SIO_000074

micromolar
notation: µM
type: SIO_000074

Nulliparous
notation: 62
subclass of: Parity
type: Class
type: QualityValue

count per molar second
notation: 1/Ms
type: SIO_000074

Interleukin-33
notation: IL33
subclass of: Protein
type: Class

8-iso Prostaglandin F2 alpha
notation: F2A8IP
subclass of: Targeted Analyte
type: Class

Owns Home
notation: 147
definition: This person owns the home they live in.
subclass of: Home Ownership
type: Class
type: QualityValue

Human Dwelling
subclass of: Human Dwelling
type: Class
type: QualityVariable

Race
subclass of: SIO_000475
subclass of: Race or Ethnicity Combined
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Healthy BMI
subclass of: Health Outcome
subclass of: Body Mass Index
subclass of: Restriction
  on property: SIO_000221
  has value: kilogram per square meter
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 0.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 25.0
  on property: SIO_000216
type: Class
type: QualityValue

Born Third
notation: 238
definition: The third born child
subclass of: Birth Order
subclass of: NCIT C25260
type: Class
type: QualityValue

Value less than LOD
subclass of: SIO_001167
type: Class

Hemolyzed (covers all three levels) and contaminated
subclass of: SIO_001167
type: Class

2, 3, 4, 6-Tetrachlorophenol
notation: TeCP2346
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

Other Material Finish
notation: 70
definition: Flooring is made from another unspecified material.
subclass of: Floor Type
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Metalloproteinase inhibitor 2
notation: TIMP2
subclass of: Protein
type: Class

count per nanomolar second
notation: 1/nMs
type: SIO_000074

millimolar
notation: mM
type: SIO_000074

Abnormality of the respiratory system
subclass of: Health Outcome
type: Class
type: QualityVariable

Tumor necrosis factor
notation: TNFA
definition: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line (PubMed:22517918).
subclass of: Protein
label: TNF-alpha
type: Class

Asthma Controller Use
subclass of: Prescription Medication and Dietary Supplements
subclass of: Restriction
  some values from: Asthma Controller Medication
  on property: SIO_000230
definition: A subclass of medical intervention that characterizes a patient's experience with using an asthma controller medication. Subclasses detail the level to which a patient has used such a medication to control their asthma symptoms, from never used to always uses.
subclass of: SIO_001398
type: QualityVariable
subclass of: Restriction
  some values from: SIO_000393
  on property: SIO_000291
subclass of: Pharmacotherapy
subclass of: Asthma Controller Medication Prescription
type: Class
equivalent class:
  union of: Has taken asthma control medications
  union of: Never takes asthma control medications

Garage
notation: 235
definition: A building, or part of a building primarily used for housing a motor vehicle or vehicles.
subclass of: Human Dwelling
type: Class
type: QualityValue

Gas Chromatography
subclass of: Chromatography
type: Class

Post-Birth 1 Minute
definition: One minute after birth of a child
subclass of: SIO_000417
type: Class

Interleukin-31
notation: IL31
subclass of: Protein
type: Class

Polygamous
notation: 45
definition: A type of living arrangement or mating system in which at least one member of a relationship has more than one mate.
subclass of: Marital Status
type: Class
type: QualityValue

count per nanomolar
notation: 1/nM
type: SIO_000074

picomolar
notation: pM
type: SIO_000074

microliter per kilogram
notation: µl/kg
type: SIO_000074

Fluticasone propionate HFA (Flovent HFA)
subclass of: Asthma Controller Medication
type: Class

1-hydroxynaphthalene
notation: NAP1
subclass of: PAH
type: Class

Lymphotoxin-alpha
notation: TNFB
subclass of: Protein
type: Class

Post-Birth 5 Minutes
definition: Five minutes after birth of a child
subclass of: SIO_000417
type: Class

Upper Respiratory Tract Infection
subclass of: Health Outcome
type: Class
type: QualityVariable

Born First
notation: 236
definition: The first born child
subclass of: Birth Order
subclass of: NCIT C25509
type: Class
type: QualityValue

Paraben
subclass of: Targeted Analyte
type: Class

nanomolar
notation: nM
type: SIO_000074

milliliter per kilogram
notation: ml/kg
type: SIO_000074

Non-smoker
notation: 59
definition: Doesn't smoke cigarettes.
subclass of: Smoking Status
type: Class
type: QualityValue

nanosecond
notation: ns
type: SIO_000074

Unplanned Caesarian Section
notation: 23
definition: Had an unplanned caesarian section.
subclass of: Caesarian Section
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Mean Height
subclass of: SIO_001109
subclass of: Height
type: Class
type: QuantityVariable

Butyl paraben
notation: BuPB
definition: Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
subclass of: Paraben
type: Class

Seasonal Population Group
definition: A Population Group organized by which season of the year the subjects were tested or studied.
subclass of: Population Group
type: Class
type: QualityVariable

Non-White Hispanic
notation: 146
definition: Non-White and Hispanic
subclass of: Non-White
subclass of: Hispanic or Latino Ethnicity
type: Class
type: QualityValue

Greater than 99th percentile
subclass of: SIO_001167
type: Class

Doctorate Degree
notation: 144
definition: The Doctor's Degree is the highest award a student can earn for graduate study. The doctor's degree classification includes such degrees in any field.
subclass of: Some Postgraduate
subclass of: Higher Education
type: Class
type: QualityValue

mono-hexyl phthalate
notation: mHxP
subclass of: Phthalate
type: Class

molal
notation: mol/kg
type: SIO_000074

foot candle
notation: ft-c
type: SIO_000074

picometer
notation: pm
type: SIO_000074

Ethylbenzene
notation: EB
definition: Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness. Chronic (long-term) exposure to ethylbenzene by inhalation in humans has shown conflicting results regarding its effects on the blood. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. Limited information is available on the carcinogenic effects of ethylbenzene in humans. In a study by the National Toxicology Program (NTP), exposure to ethylbenzene by inhalation resulted in an increased incidence of kidney and testicular tumors in rats, and lung and liver tumors in mice. EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity.
subclass of: Volatile Organic Compound
type: Class

Asthma Controller Medication
definition: A class of pharmeceutical drugs that are used to prevent or manage the onset of acute asthma before an attack occurs.
subclass of: SIO_010039
type: Class

Gravimetric Analysis Instrument
definition: Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle behind this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative quantities of the other constituents are known.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

Tetrachloroethene
notation: TCE
definition: TETRACHLOROETHYLENE is a chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
subclass of: Volatile Organic Compound
type: Class

4-hydroxychrysene
notation: CHRY4
subclass of: PAH
type: Class

Pregnancy Month 1
definition: The first month of pregnancy
subclass of: SIO_000417
type: Class

11 or More Residence Building
notation: 234
definition: A residential building that contains eleven or more apartments, town houses, condos, or other single family dwelling spaces.
subclass of: Multi Residence Building
type: Class
type: QualityValue

Oxybenzone
notation: OXB
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
subclass of: Volatile Organic Compound
type: Class

count per molar
notation: 1/M
type: SIO_000074

Gold
notation: Au
definition: GOLD is a yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
subclass of: Metal
type: Class

phthalic acid
notation: PA
definition: PHYSICAL DESCRIPTION: White crystals or fine white powder. (NTP, 1992)
subclass of: Phthalate
type: Class

DNA
subclass of: Macromolecule
type: Class

4-Hydroxybenzoic acid
notation: HB4
subclass of: Environmental Phenol
type: Class

Non-Hispanic Ethnicity
notation: 58
definition: Non-Hispanic Ethnicity
subclass of: Ethnicity
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

SIO_010058
notation: 131
type: QualityValue

A Sample has a Pairing
editorial note: This actually should be a process. What should we do?
definition: Refers to having paired samples.
subclass of: SIO_001049
was approved by: PER-Jeanette-Stingone
type: Class

N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
notation: VOCDPM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Urine grossly hematuric
subclass of: SIO_001167
type: Class

Non-Spontaneous Preterm Birth
notation: 60
subclass of: Preterm Birth
type: Class
type: QualityValue

Eats Fried Fish
notation: 229
definition: The attribute of eating fried fish.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03310717
  on property: SIO SIO 000369
type: Class
type: QualityValue

Head
subclass of: SIO_010046
type: Class

2-hydroxyfluorene
notation: FLUO2
subclass of: PAH
type: Class

megabasepair
notation: Mb
type: SIO_000074

SIO_010059
notation: 132
type: QualityValue

thousand parts per microgram
notation: x103 µL
type: SIO_000074

N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
notation: VOC2DC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Unusually high
subclass of: SIO_001167
type: Class

Eats Shell Fish
notation: 230
definition: The attribute of eating shell fish.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03411433
  on property: SIO SIO 000369
type: Class
type: QualityValue

Other GI Disease
notation: 69
editorial note: This is a temp concept that needs addressing
subclass of: SIO_010299
subclass of: Health Outcome
type: Class
type: QualityValue

Freeze/Thaw Cycles Count
definition: Number of Freeze/Thaw cycles.
subclass of: SIO_000794
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Fenton Weighted Z-Score
definition: Derived from Birth Weight, Gestational Age, and Child Sex
subclass of: SIO_001245
subclass of: Birth Outcome
subclass of: Z-Score
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    some values from: BIrth Weight
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: Fenton Preterm Growth Chart
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: Gestational Age at Birth
    on property: wasDerivedFrom
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

alpha-hexachlorocyclohexane
notation: AHCH
subclass of: Organochlorine Compound
type: Class

Styrene
notation: STY
definition: STYRENE is a colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.
subclass of: Volatile Organic Compound
type: Class

oleic acid
notation: C181N9
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
subclass of: Fatty Acid
type: Class

Domestic Partnership
notation: 42
definition: Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
subclass of: Unmarried
type: Class
type: QualityValue

SIO_001068
notation: 135
type: QualityValue

Propyl paraben
notation: PrPB
definition: Propylparaben is a Standardized Chemical Allergen. The physiologic effect of propylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of propylparaben is Allergens.
subclass of: Paraben
type: Class

Arsenocholine
notation: Arsenocholine
subclass of: Arsenic Species
type: Class

Microwave Oven Count
editorial note: Putting a note here, but it applies to all of the appliances. These are used to calculate the SES Index that was reported within one of the pilots. So, there needs to be some connection between these terms.
definition: Number of machines in the home used to heat up food using microwaves.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Acculturation
definition: Acculturation explains the process of cultural change and psychological change that results following meeting between cultures. This metaclass contains all classes that measure this process.
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
notation: VOCHPM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Value above LOD but below LLOQ
subclass of: SIO_001167
type: Class

Organochlorine Compound
subclass of: Targeted Analyte
type: Class

Eats Fresh Fish
notation: 227
definition: The attribute of eating fresh fish.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03315446
  on property: SIO SIO 000369
type: Class
type: QualityValue

Arsenous ( III) Acid
notation: Arsenous (III) Acid
subclass of: Arsenic Species
type: Class

T-Score
definition: A method for converting an individual score into a standard form. While similar to a z-score, t-score is used when the conversion is made without knowledge of the population standard deviation and mean.
subclass of: Physical And Mental Assessment
subclass of: Score
type: Class

Abdomen
subclass of: SIO_010046
type: Class

Neighbor
notation: 355
definition: A person living near or next door to another person.
subclass of: SIO_000287
subclass of: SIO_000016
subclass of: Demographic
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: SIO_000485
type: Class
type: QualityValue

Abnormal hemoglobin variant observed
subclass of: SIO_001167
type: Class

Valid measurement, results repeated and confirmed (0, 33)
subclass of: SIO_001167
type: Class

N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
notation: VOCAMC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Multiplex real-time PCR
subclass of: Polymerase Chain Reaction
type: Class

Height
definition: Height
subclass of: Anthropometry
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Eats Canned Fish
notation: 228
definition: The attribute of eating canned fish.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03302764
  on property: SIO SIO 000369
type: Class
type: QualityValue

Behavioral Experimental Paradigm
subclass of: Neurocognitive Assessment
type: Class

Torn, perforated screen
subclass of: SIO_001167
type: Class

pre-eclampsia
notation: 177
subclass of: DOID_0050828
type: Class
type: QualityValue

Failed positive control
subclass of: SIO_001167
type: Class

No Anti Malarial Use
notation: 140
subclass of: Antimalarial Use
subclass of: Prescription Medication and Dietary Supplements
type: Class
type: QualityValue

Volatile Organic Compound
subclass of: Targeted Analyte
type: Class

Malarial Retinopathy
notation: 130
definition: Retinopathy due to malaria.
subclass of: Retinopathy
type: Class
type: QualityValue

N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
notation: VOCAAM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

dehydroepiandrosterone sulfate
definition: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.
subclass of: Metabolite
subclass of: Biological Response
type: Class

Beryllium
notation: Be
definition: Beryllium. An element with the atomic symbol Be, atomic number 4, and atomic weight 9.01218. Short exposure to this element can lead to a type of poisoning known as BERYLLIOSIS.
subclass of: Metal
type: Class

cyclic peptide
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
subclass of: Metabolite
subclass of: Biological Response
type: Class

Pathogen Transmission
subclass of: Process

Copper
notation: Cu
definition: COPPER is a heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
subclass of: Metal
type: Class

Torn bag (Mitest intact, capped)
subclass of: SIO_001167
type: Class

all-cis-docosa-4, 7, 10, 13, 16, 19-hexaenoic acid
notation: C226N3
definition: A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
subclass of: Fatty Acid
type: Class

Failed negative control
subclass of: SIO_001167
type: Class

Neurocognitive Assessment
subclass of: Physical And Mental Assessment
type: Class

Mercury Species
subclass of: Targeted Analyte
type: Class

N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
notation: VOCHP2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Interleukin-15
notation: IL15
subclass of: Protein
type: Class

Zinc
notation: Zn
definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
subclass of: Metal
type: Class

Mean Concentration Range > 1000 ng/mL
notation: 322
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 1000.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
type: Class
type: QualityValue

Nervous System
definition: The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior
subclass of: SIO_010003
type: Class

Cognitive Entity
subclass of: Neurocognitive Assessment
type: Class

Methyl Paraben
notation: MePB
definition: Methylparaben is a Standardized Chemical Allergen. The physiologic effect of methylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of methylparaben is Allergens.
subclass of: Paraben
type: Class

SIO_010052
notation: 110
type: QualityValue

Diet
definition: The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.
subclass of: Diet and Nutrition
type: Class
type: QualityVariable

linoleic acid
notation: C182N6
definition: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.
subclass of: Fatty Acid
type: Class

picomoles per milliliter
notation: pmol/ml
type: SIO_000074

Unusual color
subclass of: SIO_001167
type: Class

Fibrin present
subclass of: SIO_001167
type: Class

Liquid Chromatography–Mass Spectrometer
definition: An analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin.
subclass of: Liquid Chromatography Instrument
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Clinical Measurement
definition: A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation.
subclass of: Physical And Mental Assessment
type: Class

10^3 cells per microliter
notation: 10^3 cells / µL
type: SIO_000794
type: SIO_000074

drug
type: Class

Forced Expiratory Flow at 25-75 Percent
subclass of: CMO_0000094
type: Class
type: QualityVariable

Turbid
subclass of: SIO_001167
type: Class

Fenton Preterm Growth Chart
definition: A growth chart adusted for gestational age
subclass of: SIO_000442
type: Class

Macromolecule
definition: A very large molecule, such as protein, commonly created by polymerization of smaller subunits (monomers). They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, carbohydrates and polyphenols) and large non-polymeric molecules (such as lipids and macrocycles).
subclass of: Biomolecule
type: Class

8-hydroxy-2'-deoxyguanosine
definition: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.
subclass of: Biomolecule
subclass of: Biological Response
type: Class

Inpatient Encounter
notation: 169
definition: A patient encounter where a patient is admitted to a hospital or equivalent facility.
subclass of: Destination
type: Class
type: QualityValue

Spontaneous Preterm Birth
notation: 91
subclass of: Preterm Birth
type: Class
type: QualityValue

Mercapturic acid of benzene
notation: SPMA
subclass of: PAH
type: Class

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2_PHEN3
subclass of: Environmental Phenol
type: Class

Perfume Use
notation: 74
subclass of: Personal Product Use
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Childhood Baseline
definition: A point in a study set to the initial point which occurs during the study subject's childhood period.
subclass of: SIO_000417
subclass of: Study Baseline
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

tetradecanoic acid
notation: C140
definition: A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
subclass of: Fatty Acid
type: Class

angstrom
notation: Ang
type: SIO_000074

microgram per gram
notation: µg/g
type: SIO_000074

microcurie per milliliter
notation: µcurie/ml
type: SIO_000074

East Bay, San Andreas, and Golden Gate
notation: 338
subclass of: Population Group
type: Class
type: QualityValue

picoliter
notation: pl
type: SIO_000074

Personal Product Use
definition: Personal Product Use Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

4, 4′-(1, 4-Phenylenediisopropylidene)bisphenol
notation: BPP

Medication
notation: 142
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.
subclass of: Prescription Medication and Dietary Supplements
type: Class
type: QualityVariable

African American
notation: 8
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
subclass of: Race
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Mercapturic acids of acrolein and crotonaldehyde
notation: AMA
subclass of: PAH
type: Class

2-thoxothazlidne-4-carbxylic acid(ng/mL)
notation: VOCTTC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Polymerase Chain Reaction
subclass of: SIO_001007
type: Class

nanometer
notation: nm
type: SIO_000074

Childhood Followup
definition: A point in a study that occurs after the initial baseline of the study and occurs during the study subject's childhood period.
subclass of: SIO_000417
subclass of: Study Followup
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

Valley Mt, Central Valley, and Kern
notation: 339
subclass of: Population Group
type: Class
type: QualityValue

picogram per cubic meter
notation: pg/m3
type: SIO_000074

Repeat Caesarian Section
notation: 21
definition: Had Repeat Caesarian Section
subclass of: Caesarian Section
type: Class
type: QualityValue

nanoliter
notation: nl
type: SIO_000074

megabyte
notation: MB
type: SIO_000074

Partial match
subclass of: SIO_001167
type: Class

Anthropometry
definition: Attributes pertaining to the scientific study of the measurements and proportions of the human body.
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

curie per liter
notation: curie/l
type: SIO_000074

Socioeconomic Status Index
editorial note: This is a specific index, derived from other variables. So, it should somehow be connected to this variables. Also, we may want to be more specific about the type of index that it is. Perhaps there should be a general SESIndex and then subclasses of specific measures?
definition: A measure of SES.
subclass of: SIO_000052
subclass of: Socioeconomic Status
type: Class
type: QuantityVariable

hertz
notation: Hz
type: SIO_000074

High-Performance Liquid Chromatography-Mass Spectrometry
definition: Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.
subclass of: Liquid Chromatography–Mass Spectrometer
subclass of: High-Performance Liquid Chromatography
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

2-4 Residence Building
notation: 232
definition: A residential building that contains between two and four apartments, town houses, condos, or other single family dwelling spaces.
subclass of: Multi Residence Building
type: Class
type: QualityValue

Monthly Income $3,751 to $4,166
notation: 293
subclass of: Household Income
type: Class
type: QualityValue

2-Thioxothiazolidine-4-carboxylic acid
notation: TTCA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Caregiver
definition: a paid or unpaid and without formal training member of a person's social network who helps them with activities of daily living. Caregiving is most commonly used to address impairments related to old age, disability, a disease, or a mental disorder.
subclass of: SIO_000016
subclass of: Demographic
type: Class

Interleukin-25
notation: IL17EIL25
subclass of: Protein
type: Class

Physical And Mental Assessment
definition: Physical and Mental Assessments Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Lead
notation: Pb
definition: LEAD is a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)
subclass of: Metal
type: Class

Teenager
notation: 137
definition: An individual between the ages of 13 and 19.
subclass of: Developmental Quality
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

5-10 Residence Building
notation: 233
definition: A residential building that contains between five and ten apartments, town houses, condos, or other single family dwelling spaces.
subclass of: Multi Residence Building
type: Class
type: QualityValue

Solid-Phase Sandwich ELISA
subclass of: Sandwich ELISA
was approved by: PER-Jim-McCusker
type: Class

4-hydroxyphenanthrene
notation: PHEN4
subclass of: PAH
type: Class

Monthly Income More Than $4,166
notation: 294
subclass of: Household Income
type: Class
type: QualityValue

2-amnothiazolne-4-carbxylic acid(ng/mL)
notation: VOCATC
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Liquid Chromatography - Tandem Mass Spectrometer
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS is the combination of two mass analyzers in one mass spec instrument.
subclass of: Liquid Chromatography–Mass Spectrometer
subclass of: Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Some Postgraduate
notation: 187
definition: Has begun postgraduate (masters, doctorate, etcl) and may or may not have matriculated with a graduate degree.
subclass of: Higher Education
subclass of: Restriction
  some values from: NCIT C92860
  on property: SIO_000230
type: Class
type: QualityValue

Nucleic Acid Sequencing
subclass of: SIO_001007
type: Class

femtoliter
notation: fl
type: SIO_000074

Physical Activity and Fitness
definition: Physical Activity and Fitness Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

mono (5-carboxy-2-ethylpentyl) phthalate (DEHP)
notation: MCEPP
subclass of: Phthalate
type: Class

Barium
notation: Ba
definition: BARIUM is an element of the alkaline earth group of metals. It has an atomic symbol Ba, atomic number 56, and atomic weight 138. All of its acid-soluble salts are poisonous.
subclass of: Metal
type: Class

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
notation: HPMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Room Count
definition: Total Number of Rooms in the Home
subclass of: SIO_000794
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

centiMorgan
notation: cM
type: SIO_000074

Gas Chromatographer-Tandem Mass Spectrometer
definition: MS/MS is the combination of two mass analyzers in one mass spec instrument.
subclass of: Gas Chromatographer–Mass Spectrometer
subclass of: Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

newton
notation: Ntn
type: SIO_000074

2, 4, 5-Trichlorophenol
notation: TCP245
definition: Exposure to 2, 4, 5-trichlorophenol may occur during its production or use as a pesticide. Acute (short-term) dermal exposure to 2, 4, 5-trichlorophenol may burn skin in humans. It also irritates the eyes, nose, pharynx, and lungs in humans. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of 2, 4, 5-trichlorophenol in humans. In one study, slight degenerative changes were observed in the liver and kidneys of rats chronically exposed to 2, 4, 5-trichlorophenol in their diet. EPA has classified 2, 4, 5-trichlorophenol as a Group D, not classifiable as to human carcinogenicity. PHYSICAL DESCRIPTION: Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.
subclass of: Environmental Phenol
type: Class

times per week
notation: times/week
type: SIO_000794
type: SIO_000074

2-Methylhippuric acid
notation: MHA2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Overloaded filter
subclass of: SIO_001167
type: Class

Analysis Mode
definition: Analysis Mode
subclass of: SampleIndicator
type: Class
type: QualityVariable

Monthly Income $2,918 to $3,333
notation: 291
subclass of: Household Income
type: Class
type: QualityValue

bronchiolitis
notation: 194
subclass of: DOID 850
type: Class
type: QualityValue

Value greater than ULOQ
subclass of: SIO_001167
type: Class

Matrix metalloproteinase-9
notation: MMP9
subclass of: Protein
type: Class

Monomethylarsonic Acid
notation: Monomethylarsonic Acid
subclass of: Arsenic Species
type: Class

N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
notation: DCVMA12
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Multi Residence Building
notation: 231
definition: A residential building that contains more than one apartment, town house, condo, or other single family dwelling space.
subclass of: Human Dwelling
subclass of: Residential Building
type: Class
type: QualityValue

SYNAPT G2-Si Mass Spectrometer
subclass of: Hydrogen–Deuterium Exchange Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Graduated From High School
notation: 32
definition: The quality of having graduated from High School
subclass of: Educational Status
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

2-Methylhippuric acid (ng/mL)
notation: VOC2MH
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Oral Health
definition: Oral Health Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Monthly Income $3,334 to $3,750
notation: 292
subclass of: Household Income
type: Class
type: QualityValue

Alcohol, Tobacco, and Illicit Drug Use
definition: Alcohol, Tobacco, and Illicit Drug Use Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Value below LLOQ, no LOD provided
subclass of: SIO_001167
type: Class

Fluticasone propionate DPI (Flovent Diskus)
subclass of: Asthma Controller Medication
type: Class

Multiracial
notation: 54
editorial note: Not part of current prov for Race. Should we remove this concept?
definition: Having ancestors of several or various races.
subclass of: Race
subclass of: Non-White
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

antimalarial
subclass of: drug
type: Class

Parity
definition: The number of time that a viviparous organism has given birth
subclass of: SIO_000794
subclass of: Pregnancy Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Attribute
subclass of: ScienceIndicator
type: Class

Increased Body Weight
notation: 72
definition: BMI > 25
subclass of: Body Weight Quality
subclass of: Restriction
  some values from: Restriction
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        some values from: Datatype
        on property: STATO_0000129
    on property: hasAttribute
  on property: isAttributeOf
type: Class
type: QualityValue

N-Acetyl-S- (2-carboxyethyl)-L-cysteine
notation: CEMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

kilobasepair
notation: kbp
type: SIO_000074

Pregnancy Sample
definition: A sample that is taken at or near pregnancy or birth.
subclass of: Biospecimen
type: Class

Forceps-Assisted Birth
notation: 25
definition: A vaginal birth with the assistance of forceps to extract the baby.
subclass of: Vaginal Birth
type: Class
type: QualityValue

Oily Fish
definition: Oily fish are fish that contain at least 2% fat by weight. (Oily Fish. (n.d.) Segen's Medical Dictionary. (2011))
subclass of: FOODON_03411222
type: Class

Parental Health and Family History
definition: Parental Health and Family History Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Analyzed at a later date than rest of samples on worksheet (not a repeat)
subclass of: SIO_001167
type: Class

4-hydroxybenzophenone
notation: OH4BP
subclass of: Benzophenone
type: Class

N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
notation: DHBMA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

centiRay
notation: cR
type: SIO_000074

RNA Sequencing
subclass of: Nucleic Acid Sequencing
type: Class

Sustained Physical Activity
definition: Physical activity that is at least 30 minutes in duration.
subclass of: Physical Activity
type: Class
type: QualityVariable

Monthly Income $2,501 to $2,917
notation: 290
subclass of: Household Income
type: Class
type: QualityValue

Foster
definition: Fosterage, the practice of a family bringing up a child not their own, differs from adoption in that the child's parents, not the foster-parents, remain the acknowledged parents. In many modern western societies foster care can be organized by the state to care for children with troubled family backgrounds, usually on a temporary basis. In many pre-modern societies fosterage was a form of patronage, whereby influential families cemented political relationships by bringing up each other's children, similar to arranged marriages, also based on dynastic or alliance calculations.
subclass of: Non-Biological Relative
type: Class

Panel change
subclass of: SIO_001167
type: Class

Analyte
subclass of: SIO_010004
type: Class

PCB118
notation: PCB118
subclass of: Polychlorobiphenyl
type: Class

N-methyl Perfluorooctane sulfonamido acetic acid
notation: NMFOSAA
subclass of: PFC
type: Class

Intensive Care Unit
notation: 168
definition: A health care facility unit that provides intensive care to critically ill patients and patients with complex medical problems who require constant monitoring or special therapy.
subclass of: Destination
type: Class
type: QualityValue

Metabolite
definition: A substance formed in or necessary for metabolism
subclass of: Analyte
type: Class

Triclocarban
notation: TCC
definition: Triclocarban is a triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interrupts cell membrane synthesis and leads to bacterial growth inhibition.
subclass of: Environmental Phenol
type: Class

Pre-Pregnancy
definition: The time before a pregnancy.
subclass of: SIO_000417
subclass of: From Conception
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
type: Class

Daughter
definition: The female offspring in relation to her parents.
subclass of: Child
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010052
    on property: hasAttribute
type: Class

Pregnancy Month 6
definition: The sixth month of pregnancy
subclass of: SIO_000417
type: Class

Annual Income $75,000 to $84,999
notation: 262
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Ethyl mercury (C2H5Hg+)
notation: C2H5Hg
subclass of: Mercury Species
type: Class

parts per hundred
notation: pph
type: SIO_000074

megavolt
notation: MV
type: SIO_000074

hemoglobin measurement
subclass of: Concentration
type: Class

White
notation: 102
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
subclass of: Race
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Glucan
subclass of: Environmental Exposure
type: Class

Prenatal Nonsmoker
notation: 76
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
definition: Could be a former smoker or a non-smoker, so neither should be encoded as the superclass.
subclass of: Non-smoker
type: Class
type: QualityValue

Health Outcome
subclass of: StudyIndicator
type: Class

Annual Income $65,000 to $74,999
notation: 263
subclass of: Annual Income $50,000 to $99,999
subclass of: Household Income
type: Class
type: QualityValue

Public or No Insurance
notation: 335
subclass of: Private Insurance or Self Pay
type: Class
type: QualityValue

Father
notation: 188
definition: The male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental legal and social relationship with the child that carries with it certain rights and obligations. An adoptive father is a male who has become the child's parent through the legal process of adoption. A biological father is the male genetic contributor to the creation of the baby, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a male who is the husband of a child's mother and they may form a family unit, but who generally does not have the legal rights and responsibilities of a parent in relation to the child.
subclass of: Parent
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010048
    on property: hasAttribute
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Interleukin-9
notation: IL9
subclass of: Protein
type: Class

3-hydroxyfluorene
notation: FLUO3
subclass of: PAH
type: Class

picovolt
notation: pV
type: SIO_000074

Process
subclass of: ScienceIndicator
type: Class

3-Hydroxypropyl-1-methyl mercapturic acid + 3-Hydroxypropyl-2-methyl mercapturic acid + 3-Hydroxypropyl-3-methyl mercapturic acid
notation: HMPMA

2, 4, 5, 6-Tetrachlorophenol
notation: TeCP2456
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

Single-Family House
notation: 175
definition: A residential building designed to hold one family.
subclass of: Residential Building
type: Class
type: QualityValue

Average Folic Acid Supplement Intake
subclass of: SIO_001109
subclass of: Uses Folic Acid Supplement
type: Class
type: QuantityVariable

Monthly Income $2,084 to $2,500
notation: 289
subclass of: Household Income
type: Class
type: QualityValue

Planned Caesarian Section
notation: 18
definition: Planned caesarian section.
subclass of: Caesarian Section
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Annual Income More Than $95,000
notation: 260
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

year
notation: y
type: SIO_000074

Triclosan
notation: TCS
definition: Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
subclass of: Environmental Phenol
type: Class

parts per million
notation: ppm
type: SIO_000074

newton per meter
notation: N/m
type: SIO_000074

Tungsten
notation: W
definition: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. TUNGSTEN is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
subclass of: Metal
type: Class

Femur
subclass of: SIO_010046
type: Class

2-Aminothiazoline-4-carboxylic acid
notation: ATCA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Hemoglobin Genotype SS
notation: 346
subclass of: Genotype
subclass of: SCD Genotype
type: Class
type: QualityValue

Average B6 Supplement Intake
equivalent class: Class
  union of: Public Insurance
  union of: No Insurance / Self-funded
subclass of: SIO_001109
subclass of: Uses B6 Supplement
type: Class
type: QuantityVariable

Post-Pregnancy
definition: The period after birth.
subclass of: SIO_000417
subclass of: From Birth
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: birthing
was approved by: PER-Jeanette-Stingone
type: Class

Multi-Family House
notation: 176
definition: A residential building designed to hold more than one family.
subclass of: Residential Building
type: Class
type: QualityValue

Annual Income $85,000 to $94,999
notation: 261
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Transfer
notation: 172
definition: The act of conveying or transporting from one place to another.
subclass of: Destination
type: Class
type: QualityValue

parts per thousand
notation: ppth
type: SIO_000074

month
notation: m
type: SIO_000074

katal
notation: kat
type: SIO_000074

Monthly Income $1,251 to $1,666
notation: 287
subclass of: Household Income
type: Class
type: QualityValue

Descendant
definition: The child of a human, or any grandchild, great-grandchild, and so on.
subclass of: Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Ancestor
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class

2, 3', 4, 4'-Tetrabromodiphenyl ether
notation: BDE66
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Annual Income $90,001 to $120,000
notation: 165
definition: Personal or family annual income bwtween $90,001 and $120,000
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Phenylglyoxylic acid
notation: PGA
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

micromole
notation: µmol
type: SIO_000074

nanograms per liter
notation: ng/L
type: SIO_000074

Uses B6 Supplement
notation: 334
subclass of: nutrition intake
subclass of: Restriction
  some values from: B6 Vitamin Supplement
  on property: SIO_000230
type: Class
type: QualityValue

radian
notation: rad
type: SIO_000074

microampere
notation: µA
type: SIO_000074

Platelet
definition: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
subclass of: Blood Component
type: Class

No preservative added
subclass of: SIO_001167
type: Class

Short Stay
notation: 170
definition: A patient encounter where the patient is admitted to a health care facility for a predetermined length of time, usually less than 24 hours. [def-source:
subclass of: Destination
type: Class
type: QualityValue

Trans-Nonachlor
notation: TNON
subclass of: Organochlorine Compound
type: Class

2, 4, 4'-Tribromodiphenyl ether
notation: BDE28
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Phenylglyoxylic acid(ng/mL)
notation: VOCPHG
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Monthly Income $1,667 to $2,083
notation: 288
subclass of: Household Income
type: Class
type: QualityValue

Annual Income More Than $120,000
notation: 166
definition: Personal or family annual income greater than $120,000
subclass of: Annual Income More Than $100,000
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Never exposed to second hand smoke from E-cigarettes
notation: 259
subclass of: environmental e-cigarette smoke exposure
type: Class
type: QualityValue

Car
notation: 248
subclass of: Human Dwelling
type: Class
type: QualityValue

Average Iron Supplement Intake
subclass of: SIO_001109
subclass of: Uses Iron Supplement
type: Class
type: QuantityVariable

dyne per cm
notation: dyn/cm
type: SIO_000074

milliampere
notation: mA
type: SIO_000074

No Hct, Hct=40 assumed
subclass of: SIO_001167
type: Class

Medical Therapy Procedure
definition: Medical Therapy Procedure to aide in treatment.
subclass of: SIO_001024
subclass of: Medical History
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

2, 2', 4, 4', 6-Pentabromodiphenyl ether
notation: BDE100
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Benzo[a]pyrene tetraol
notation: BAPT
subclass of: PAH
type: Class

Annual Income $50,001 to $75,000
notation: 163
definition: Personal or family annual income bwtween $50,001 and $75,000
subclass of: Household Income
type: Class
type: QualityValue

decibel
notation: dB
type: SIO_000074

Uses Folic Acid Supplement
notation: 333
subclass of: nutrition intake
subclass of: Restriction
  some values from: Folic Acid Vitamin Supplement
  on property: SIO_000230
type: Class
type: QualityValue

Monthly Income $417 to $833
notation: 285
subclass of: Household Income
type: Class
type: QualityValue

picogram per milliliter
notation: pg/mL
type: SIO_000074

steradian
notation: sr
type: SIO_000074

poise
notation: Poise
type: SIO_000074

colony forming unit
notation: cfu
type: SIO_000074

Obvious coarse debris
subclass of: SIO_001167
type: Class

neuron
subclass of: Cell
type: Class

Home
notation: 167
definition: A person's place of residence.
subclass of: Destination
type: Class
type: QualityValue

Birth
definition: The ending of a pregnancy by one or more babies leaving a woman's uterus by vagina passage or c-section.
subclass of: SIO_000417
subclass of: From Birth
subclass of: Beginning
was approved by: PER-Jeanette-Stingone
type: Class

Monthly Income $834 to $1,250
notation: 286
subclass of: Household Income
type: Class
type: QualityValue

2, 2', 4, 4'-Tetrabromodiphenyl ether
notation: BDE47
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

B6 Vitamin Supplement
subclass of: NCIT C944
subclass of: Restriction
  some values from: CHEBI_27306
  on property: SIO_000313
type: Class

Perfluroundecanoic acid
notation: PFUNDA
subclass of: PFC
type: Class

Annual Income $75,001 to $90,000
notation: 164
definition: Personal or family annual income bwtween $75,001 and $90,000
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Mometasone HFA (Asmanex HFA)
subclass of: Asthma Controller Medication
type: Class

octadecanoic acid
notation: C180
definition: A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
subclass of: Fatty Acid
type: Class

1-hydroxypyrene
notation: PYR1
subclass of: PAH
type: Class

eosinophilic esophagitis
subclass of: esophageal disease
type: Class

pascal second
notation: Pas
type: SIO_000074

Cerebral Malaria
notation: 126
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
subclass of: Malaria
type: Class
type: QualityValue

Red Blood Cell
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
subclass of: Blood Component
type: Class

SIO_000751
notation: 133
type: QualityValue

Not Current Student
notation: 141
definition: The state of an individual not currently engaged in educational activity as a pupil.
subclass of: Educational Status
type: Class
type: QualityValue

2, 4'-DDT
notation: OPDDT
subclass of: Organochlorine Compound
type: Class

Education
definition: The act or process of imparting or acquiring knowledge.
subclass of: SIO_000026
subclass of: Socioeconomic Status
subclass of: Demographic
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Relative Time
definition: A time in relation to an event
subclass of: SIO_000391
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Process
type: Class

Mean Concentration Range 200 - 500 ng/mL
notation: 320
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 200.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 500.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
type: Class
type: QualityValue

Environmental Exposure
editorial note: may need to refine this name in order to clearly differentiate from environmental exposures measured within CHEAR. Perhaps ExternalEnvironmental Exposure. Ok for now but we may want to discuss.
definition: EnvironmentalExposure Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Thallium
notation: Tl
definition: THALLIUM is a heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
subclass of: Metal
type: Class

Methylation Assay
definition: An assay that measures the methylation levels of sections of a genome.
subclass of: SIO_001007
type: Class

mono-(2-ethylhexyl) terephthalate
notation: MEHTP

Infinium Methylation EPIC BeadChip Assay
subclass of: Microarray Assay
subclass of: Methylation Assay
type: Class

cell in vitro
subclass of: Cell
type: Class

Interleukin-1 beta
notation: IL1B
definition: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
subclass of: Protein
type: Class

Analysis
definition: The value contains concentrations from the study sample
subclass of: Analyte
type: Class

Mean Concentration Range 500 - 1000 ng/mL
notation: 321
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 500.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 1000.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
type: Class
type: QualityValue

Hexachlorobenzene
notation: HCB
subclass of: Organochlorine Compound
type: Class

Electrospray Ionization Mass Spectrometry
definition: Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.
subclass of: MassSpectrometry
was approved by: PER-Jim-McCusker
type: Class

Mental Health
definition: Mental Health Indicator
subclass of: Physical And Mental Assessment
was approved by: PER-Jeanette-Stingone
type: Class

Insurance Type
definition: Insurance Type
subclass of: Insurance
type: Class
type: QualityVariable

FEV1/FVC Ratio
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

Departure
notation: 174
definition: The act of leaving a destination.
subclass of: Destination
type: Class
type: QualityValue

femtomolar
notation: fM
type: SIO_000074

hypertension
notation: 178
subclass of: DOID_0050828
type: Class
type: QualityValue

From Birth
definition: A time in relation to a birth
subclass of: Relative Time
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: birthing
type: Class

Mean Concentration Range 30 - 100 ng/mL
notation: 318
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 100.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 30.0
  on property: SIO_000216
type: Class
type: QualityValue

Annual Income $15,000 to $24,999
notation: 268
subclass of: Annual Income $15,000 to $29,999
subclass of: Household Income
type: Class
type: QualityValue

Mobile Home
notation: 247
subclass of: Human Dwelling
type: Class
type: QualityValue

3, 4-Dihydroxy-benzoic acid methyl ester
notation: OHMeP
subclass of: Environmental Phenol
type: Class

Exposure Monitoring Instrument
definition: A physical instrument that monitors the environment for chemical exposures.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

Microarray Assay
definition: An assay that uses a microarray to perform measurements.
subclass of: SIO_001007
type: Class

mole fraction
notation: chi
type: SIO_000074

4, 4'-cyclo-hexylidenebisphenol
notation: BPZ

Circumference
subclass of: Anthropometry
type: Class
type: QuantityVariable

Mean Concentration Range 100 - 200 ng/mL
notation: 319
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 100.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 200.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
type: Class
type: QualityValue

From Conception
definition: A time in relation to a conception
subclass of: Relative Time
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Conceiving
type: Class

Monoisopropyl phthalate
notation: MiPP
subclass of: Phthalate
type: Class

Arsenobetaine
notation: Arsenobetaine
subclass of: Arsenic Species
type: Class

Enzyme Immunoassay
subclass of: Immunoassay
type: Class

MicroPEM
definition: The MicroPEM device monitors individual exposures to very fine airborne particles—or particulate matter—at two sizes. PM10 has a diameter of less than 10 micrometers (PM10), which is approximately 1/30th the size of a human hair, and PM2.5, which at diameters of less than 2.5 micrometers, is even smaller.
subclass of: Exposure Monitoring Instrument
was approved by: PER-Jim-McCusker
type: Class

normal
notation: Norm
type: SIO_000074

Hospital Readmissions
definition: An episode when a patient who had been discharged from a hospital is admitted again within a specified time interval.
subclass of: SIO_000794
subclass of: Hospital Utilization
type: Class

microeinstein per square meter per second
notation: µeinstein/sm2
type: SIO_000074

Entity
subclass of: ScienceIndicator
type: Class

Quit Smoking
notation: 82
definition: Quit Smoking Cigarettes
subclass of: Previous Smoker
type: Class
type: QualityValue

BIrth Weight
equivalent class: Class
  intersection of: SIO_000279
  intersection of: Restriction
    on property: measuredAt
    all values from: Birth
type: Class
type: QuantityVariable

Annual Income $35,000 to $44,999
notation: 266
subclass of: Annual Income $30,000 to $49,999
subclass of: Household Income
type: Class
type: QualityValue

Inductively Coupled Plasma Mass Spectrometer
definition: A type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 10^15 (part per quadrillion, ppq) on non-interfered low-background isotopes. This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Mean Concentration Range 0 - 10 ng/mL
notation: 316
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 0.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 10.0
  on property: SIO_000216
type: Class
type: QualityValue

mass percentage
notation: w/w
type: SIO_000074

radian per second per second
notation: alpha
type: SIO_000074

picosecond
notation: ps
type: SIO_000074

Annual Income $25,000 to $34,999
notation: 267
subclass of: Annual Income $20,001 to $40,000
subclass of: Household Income
type: Class
type: QualityValue

Experimental Group
notation: 201
definition: A study population that receives the intervention that is the focus of the study.
subclass of: Population Group
type: Class
type: QualityValue

Beginning
definition: A time relative to the beginning of an event
subclass of: Relative Time
subclass of: Restriction
  on property: hasValue
  has value: 1
type: Class

Immunoturbidimetry
definition: An analytical technique that uses light scattering, a physical phenomenon resulting from the interaction of light with particles in solution, to measure the concentration of particles. The photometric signal is generated by a decrease in light intensity as a direct consequence of increasing turbidity in the reaction well. Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be optically detected by an photometer.
subclass of: SIO_001007
was approved by: PER-Jim-McCusker
type: Class

Environmental Material
subclass of: SIO_010412
type: Class

Mean Concentration Range 10 - 30 ng/mL
notation: 317
subclass of: Mean Concentration
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 10.0
  on property: SIO_000216
subclass of: Restriction
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 30.0
  on property: SIO_000216
subclass of: Restriction
  on property: SIO_000221
  has value: nanogram per milliliter
type: Class
type: QualityValue

Season
notation: 209
subclass of: SIO_000417
subclass of: Environmental Exposure
type: Class
type: QualityValue

Histidine-rich protein PFHRP-II
subclass of: Protein
type: Class

Measurement
subclass of: Physical And Mental Assessment
type: Class
type: QualityVariable

Phthalate
subclass of: Targeted Analyte
type: Class

meter per second per second
notation: m/s2
type: SIO_000074

Nail
definition: A nail that is part of a manual digit. [database_cross_reference: OBOL:automatic]
subclass of: Tissue
type: Class

gamma-hexachlorocyclohexane
notation: GHCH
subclass of: Organochlorine Compound
type: Class

watt per steradian
notation: W/sr
type: SIO_000074

(9Z)-hexadecenoic acid
notation: C161N7
definition: A hexadecenoic acid with a cis-double bond at position C-9.
subclass of: Fatty Acid
type: Class

Alta, Far Northern, and Redwood Coast
notation: 336
subclass of: Population Group
type: Class
type: QualityValue

Prenatal Smoker
notation: 77
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
definition: The quality of having smoked while being pregnant.
subclass of: Smoker
type: Class
type: QualityValue

Mother
notation: 189
definition: A mother is the female parent of a child. Mothers are women who inhabit or perform the role of bearing some relation to their children, who may or may not be their biological offspring. Thus, dependent on the context, women can be considered mothers by virtue of having given birth, by raising their child(ren), supplying their ovum for fertilisation, or some combination thereof. Such conditions provide a way of delineating the concept of motherhood, or the state of being a mother. Women who meet the third and first categories usually fall under the terms 'birth mother' or 'biological mother', regardless of whether the individual in question goes on to parent their child. Accordingly, a woman who meets only the second condition may be considered an adoptive mother, and those who meet only the third a surrogacy mother. The above concepts defining the role of mother are neither exhaustive nor universal, as any definition of 'mother' may differ based on how social, cultural, and religious roles are defined.
subclass of: Parent
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010052
    on property: hasAttribute
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

5+ Years of College, Technical, or Vocational Training
notation: 315
subclass of: Educational Status
subclass of: Higher Education
type: Class
type: QualityValue

Annual Income $55,000 to $64,999
notation: 264
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income $40,001 to $70,000
subclass of: Household Income
type: Class
type: QualityValue

Electron-Detachment Dissociation (EDD)
subclass of: TandemMassSpectrometry
type: Class

Liquid Chromatography Instrument
definition: A separation technique in which the mobile phase is a liquid. It can be carried out either in a column or a plane. Present day liquid chromatography that generally utilizes very small packing particles and a relatively high pressure is referred to as high performance liquid chromatography (HPLC).
subclass of: Chromatography Instrument
was approved by: PER-Jim-McCusker
type: Class

Protocatechuic acid ethyl ester
notation: OHEtP
subclass of: Environmental Phenol
type: Class

Lymphocyte
definition: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
subclass of: Leukocyte
type: Class

hour
notation: h
type: SIO_000074

volume percentage
notation: %(v/v)
type: SIO_000074

nanovolt
notation: nV
type: SIO_000074

Private Insurance
notation: 103
subclass of: Private Insurance or Self Pay
type: Class
type: QualityValue

North Bay
notation: 337
subclass of: Population Group
type: Class
type: QualityValue

Annual Income $45,000 to $54,999
notation: 265
subclass of: Annual Income $40,001 to $70,000
subclass of: Household Income
type: Class
type: QualityValue

Corticosteroid Burst
subclass of: SIO_001398
subclass of: Prescription Medication and Dietary Supplements
subclass of: Restriction
  some values from: CHEBI_50858
  on property: SIO_000230
subclass of: Restriction
  some values from: SIO_000393
  on property: SIO_000291
type: Class
type: QuantityVariable

Known Food Allergies
subclass of: Health Outcome
type: Class
type: QualityVariable

Son
definition: A son is a male offspring; a boy or man in relation to his parents.
subclass of: Child
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    some values from: SIO_010048
    on property: hasAttribute
type: Class

Toluene
notation: TOL
definition: Toluene is a widely used industrial solvent.
subclass of: Volatile Organic Compound
type: Class

Hospitalization
notation: 104
definition: Admission to a hospital
subclass of: SIO_001024
subclass of: Hospital Utilization
type: Class
type: QualityValue

radian per second
notation: rad/s
type: SIO_000074

mass volume percentage
notation: (w/v)
type: SIO_000074

minute
notation: min
type: SIO_000074

4, 4'-DDE
notation: PPDDE
subclass of: Organochlorine Compound
type: Class

hexadecanoic acid
notation: C160
definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
subclass of: Fatty Acid
type: Class

deciliter
notation: dl
type: SIO_000074

gamma-linolenic acid
notation: C183N6
definition: A C18, ω-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
subclass of: Fatty Acid
type: Class

Gas Chromatographer–Mass Spectrometer
definition: Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of material samples obtained from planet Mars during probe missions as early as the 1970s. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification. Like liquid chromatography–mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.
subclass of: Gas Chromatography Instrument
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

micrograms per deciliter
notation: µg/dl
type: SIO_000074

Small clot present
subclass of: SIO_001167
type: Class

Metabolite
definition: The intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.
subclass of: Small Molecule
type: Class

Parent
definition: A parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A biological parent is a person whose gamete resulted in a child, a male through the sperm, and a female through the ovum. Parents are first-degree relatives and have 50% genetic meet. A female can also become a parent through surrogacy. Some parents may be adoptive parents, who nurture and raise an offspring, but are not actually biologically related to the child. Orphans without adoptive parents can be raised by their grandparents or other family members.
subclass of: Ancestor
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Child
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class

Annual Income $14,999 or Less
notation: 219
subclass of: Household Income
type: Class
type: QualityValue

Electron Capture Dissociation (ECD)
subclass of: TandemMassSpectrometry
type: Class

Destination
notation: Dest
definition: A place to which one is traveling or to which something is sent.
subclass of: Healthcare Access
type: Class
type: QualityVariable

Whole Blood
definition: A fluid that is composed of blood plasma and erythrocytes. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Blood][database_cross_reference: https://github.com/obophenotype/uberon/issues/9][database_cross_reference: FMA:9670]
subclass of: Bodily Fluid
type: Class

Creatinine
notation: CRE
definition: Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
subclass of: Targeted Analyte
type: Class

Eosinophil Percentage
subclass of: Physical And Mental Assessment
type: Class
type: QuantityVariable

Mometasone DPI (Asmanex)
subclass of: Asthma Controller Medication
type: Class

Haptoglobin
notation: HAPTOGLOBIN
subclass of: Protein
type: Class

gram per deciliter
notation: g/dl
type: SIO_000074

2, 3, 4, 5-Tetrachlorophenol
notation: TeCP2345
definition: PHYSICAL DESCRIPTION: Needles (from petroleum ether, ligroin) or beige solid. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

Allergy
notation: 279
subclass of: SIO_010056
type: Class
type: QualityValue

Perfluorooctanesulfonate
notation: PFDODA
subclass of: PFC
type: Class

HPLC with Fluorescence Level Detector
definition: HPLC paired with a Fluorescence Level Detector. Fluorescence spectroscopy (also known as fluorometry or spectrofluorometry) is a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light. A complementary technique is absorption spectroscopy. In the special case of single molecule fluorescence spectroscopy, intensity fluctuations from the emitted light are measured from either single fluorophores, or pairs of fluorophores.
subclass of: High-Performance Liquid Chromatography
type: Class

Slightly hemolyzed
subclass of: SIO_001167
type: Class

Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer
subclass of: Ultra Performance Liquid Chromatography - Mass Spectrometer
subclass of: Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Metal
definition: For environmental purposes, HHEAR metals are metals and metalliods, as originally defined in CHEAR.
subclass of: Element
type: Class

Household Appliance Count
definition: Total number of appliances that can be found in the home.
subclass of: SIO_000794
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Early Childhood Vigilance Test
definition: a computer-based assessment of sustained attention during which the child is required to watch a screen where various animated stimuli disappear and reappear
subclass of: Neurocognitive Assessment
type: Class

Annual Income $15,000 to $29,999
notation: 220
subclass of: Household Income
type: Class
type: QualityValue

2, 4-Dichlorophenol
notation: DCP24
definition: 2, 4-dichlorophenol is a colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
subclass of: Environmental Phenol
type: Class

Z-Score
definition: A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.
subclass of: Anthropometry
type: Class

microunits per milliliter
notation: µU/mL
type: SIO_000074

Fast Food Consumption Frequency
definition: Frequency of Fast Food Consumption.
subclass of: Diet Quantity
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Specimen analyzed in singlicate for an assay that requires duplicates
subclass of: SIO_001167
type: Class

Education Grade 4
notation: 116
definition: Finished grade 4
subclass of: Elementary School
type: Class
type: QualityValue

Maternal Weight Gain
definition: The amount of weight gained during a pregnacy.
subclass of: Pregnancy Characteristic
subclass of: Weight
was approved by: PER-Jeanette-Stingone
type: Class

Genotype
subclass of: Medical History
type: Class

Chloroform
notation: CFRM
definition: CHLOROFORM is a commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
subclass of: Volatile Organic Compound
type: Class

micrograms per meter cubed
notation: µg/m3
type: SIO_000074

Fresh Vegetable Consumption Frequency
definition: Frequency of Fresh Vegetable Consumption.
subclass of: Diet Quantity
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Head of Household
definition: The Person is the head of Household
definition: Head of Household is a filing status for individual United States taxpayers. To use the Head of Household filing status, a taxpayer must: (1) Be unmarried or considered unmarried at the end of the year (2) Have paid more than half the cost of keeping up a home for the tax year (either one's own home or the home of a qualifying parent) (3) Usually have a qualifying person who lived with the head in the home for more than half of the tax year unless the qualifying person is a dependent parent.
subclass of: SIO_000016
subclass of: Demographic
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Household
was approved by: PER-Jeanette-Stingone
label: Head Of Household
type: Class

Socioeconomic Status
definition: Socioeconomic Status Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Mercapturic acids of 1, 3-butadiene
notation: HEMA
subclass of: Tobacco Metabolite
type: Class

Electron Transfer Dissociation (ETD)
subclass of: TandemMassSpectrometry
type: Class

nutrition intake
definition: Nutrition intake is the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.
subclass of: Diet and Nutrition
type: Class
type: QualityVariable

English Language
notation: 243
definition: The English Language
subclass of: Acculturation
type: Class
type: QualityValue

3-Chlorophenol
notation: MCP3
definition: PHYSICAL DESCRIPTION: White crystals with an odor of phenol. Sinks in and slowly dissolves in water. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

Hispanic or Latino Ethnicity
notation: 47
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term “Spanish origin” can also be used in addition to “Hispanic or Latino.”
subclass of: Ethnicity
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Cotinine
notation: COT
definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
subclass of: Tobacco Metabolite
type: Class

1 or 2 Years of College, Technical, or Vocational Training
notation: 313
subclass of: Educational Status
subclass of: Higher Education
type: Class
type: QualityValue

Anatabine
notation: ANAT
subclass of: Tobacco Metabolite
type: Class

United States of America
notation: 184
type: QualityValue

Difference
definition: Variables derived from taking the difference of two other variables. For example, the first difference of a time series {yt} is defined as Dyt = yt - yt-1
subclass of: SIO_000052
type: Class

Haircare Product Use
notation: 30
subclass of: Personal Product Use
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Element
subclass of: Targeted Analyte
type: Class

Patella
definition: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella.
subclass of: SIO_010046
type: Class

Technical Post-Middle School
notation: 94
definition: Attended a Technical Post-Middle School.
subclass of: Educational Status
subclass of: Technical School
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Mercury
notation: Hg
definition: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
subclass of: Metal
type: Class

micromolal
notation: µmol/kg
type: SIO_000074

3 or 4 Years of College, Technical, or Vocational Training
notation: 314
subclass of: Educational Status
subclass of: Higher Education
type: Class
type: QualityValue

Diet and Nutrition
definition: Diet and Nutrition Indicator
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Gel Electrophoresis
definition: Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
subclass of: SIO_001007
type: Class

m-Xylene*
notation: MXY
definition: M-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
subclass of: Volatile Organic Compound
type: Class

Ever Smoked
notation: 136
definition: The quality of having smoking in the past.
subclass of: Smoking Status
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Child
definition: A relationship with a parent (such as sons and daughters of any age).
subclass of: Descendant
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Parent
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class

Control Group
notation: 200
definition: A group used as a standard of comparison in a control experiment.
subclass of: Population Group
type: Class
type: QualityValue

72 kDa type IV collagenase
notation: MMP2
subclass of: Protein
type: Class

Drug Other Than Antimalarial Use
subclass of: SIO_001398
subclass of: Pharmacotherapy
subclass of: Restriction
  some values from: SIO_000393
  on property: SIO_000291
subclass of: Restriction
  some values from: drug other than antimalarial
  on property: SIO_000230
type: Class

Asthma Diagnosis Group
notation: 312
subclass of: Diagnosis Group
type: Class
type: QualityValue

2,3-dinor-8-iso Prostaglandin F2 alpha
notation: F2A23D
subclass of: Targeted Analyte
type: Class

Sleep Characterisitic
definition: Sleep Characterisitics Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

2-hydroxyphenanthrene
notation: PHEN2
subclass of: PAH
type: Class

Direct Mercury Analyzer
definition: Direct mercury analysis incorporates the following sequence: thermal decomposition, catalytic conversion, amalgamation, and atomic absorption spectrophotometry. Controlled heating stages are implemented to first dry and then thermally decompose a sample introduced into a quartz tube. A continuous flow of oxygen carries the decomposition products through a hot catalyst bed where halogens, nitrogen, and sulfur oxides are trapped. All mercury species are reduced to Hg(0) and are then carried along with reaction gases to a gold amalgamator where the mercury is selectively trapped. All nonmercury vapors and decomposition products are flushed from the system by the continuous flow of gas. The amalgamator is subsequently heated and releases all trapped mercury to the single-beam, fixed-wavelength atomic absorption spectrophotometer. Absorbance is measured at 253.7 nm as a function of mercury content
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

Hydrogen–Deuterium Exchange Mass Spectrometer
definition: Hydrogen–deuterium exchange mass spectrometry can determine the overall deuterium content of molecules which have undergone H/D exchange. Because of the sample preparation required, it is typically considered to provide an accurate measurement of non-exchangeable hydrogen atoms only.
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
type: Class

Weight
definition: The resulting Force from the interaction between a person's Mass and Gravity.
subclass of: SIO_000279
subclass of: Anthropometry
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

DVD Player Count
definition: Number of devices in the home that play DVDs.
subclass of: Household Appliance Count
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

picomolal
notation: pmolal
type: SIO_000074

Waist
definition: The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso.
subclass of: SIO_010046
type: Class

Ozone
subclass of: Environmental Exposure
type: Class

Bedroom
definition: A room in a human dwelling that is the primary location where one or more occupants sleep.
subclass of: ENVO_01000426
type: Class

Environmental Phenol
subclass of: Targeted Analyte
type: Class

Childhood Followup 3
definition: A point in a study that occurs after the second follow-up point in the study and occurs during the study subject's childhood period.
subclass of: SIO_000417
subclass of: Study Followup
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

Short sample; sample probe picked up incomplete volume first time
subclass of: SIO_001167
type: Class

Dilution required
subclass of: SIO_001167
type: Class

Hospital Utilization
definition: Hospital Utilization
subclass of: Healthcare Access
was approved by: PER-Jeanette-Stingone
type: Class

Diet Treatment Medical Therapy
notation: 26
definition: Diet Treatment is a form of Medical Therapy.
subclass of: Medical Therapy Procedure
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

Technical Post Primary School
notation: 95
definition: Attended a Technical Post Primary School
subclass of: Educational Status
subclass of: Technical School
subclass of: High School or Less
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityValue

nanomolal
notation: nmolal
type: SIO_000074

Divorced
notation: 40
definition: Indicates a person whose marriage has been legally dissolved and has not remarried.
subclass of: Unmarried
type: Class
type: QualityValue

Long Range Polymerase Chain Reaction
definition: Amplification of DNA lengths that cannot typically be amplified using routine PCR methods or reagents. For simple DNA templates, polymerases optimized for Long Range PCR can amplify up to 30 kb and beyond. For complex, genomic templates, 20 kb is a typical target.
subclass of: Polymerase Chain Reaction
was approved by: PER-Jim-McCusker
type: Class

Eats Fish Sticks
notation: 225
definition: The attribute of eating fish sticks.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03311701
  on property: SIO SIO 000369
type: Class
type: QualityValue

times per year
notation: times / year
type: SIO_000794
type: SIO_000074

Matrilysin
notation: MMP7
subclass of: Protein
type: Class

Adopted
definition: Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents, and, in so doing, permanently transfers all rights and responsibilities, along with filiation, from the biological parent or parents.
subclass of: Non-Biological Relative
type: Class

lux
notation: lx
type: SIO_000074

2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
notation: BDE154
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

microvolt
notation: µV
type: SIO_000074

Annual Income $15,001 to $30,000
notation: 161
definition: Personal or family annual income bwtween $15,001 and $30,000
subclass of: Household Income
type: Class
type: QualityValue

Moderately hemolyzed
subclass of: SIO_001167
type: Class

Stromelysin-2
notation: MMP10
subclass of: Protein
type: Class

monooxoisononyl phthalate (DiNP)
notation: MONP

Manganese
notation: Mn
definition: MANGANESE is a trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
subclass of: Metal
type: Class

Titanium
notation: Ti
definition: TITANIUM is a dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
subclass of: Metal
type: Class

2, 4, 6-Trichlorophenol
notation: TCP246
definition: 2 4 6-Trichlorophenol is a synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2, 4, 6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2, 4, 6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05)
subclass of: Environmental Phenol
type: Class

Separated
notation: 41
definition: Indicates a person living apart from his/her spouse by legal arrangement.
subclass of: Married
type: Class
type: QualityValue

Marital Status
definition: A person's current conjugal status.
subclass of: NCIT C44456
was approved by: PER-Jeanette-Stingone
type: Class
type: QualityVariable

Ancestor
definition: An ancestor or forebear is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth). Ancestor is "any person from whom one is descended. In law the person from whom an estate has been inherited."
subclass of: Relative
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Restriction
      on property: hasRole
      all values from: Descendant
    intersection of: SIO_000485
was approved by: PER-Jeanette-Stingone
type: Class

Eats Oily Fish
notation: 226
definition: The attribute of eating oily fish.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: Oily Fish
  on property: SIO SIO 000369
type: Class
type: QualityValue

Retina
definition: The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
subclass of: SIO_010003
type: Class

kilovolt
notation: kV
type: SIO_000074

2, 2', 4, 4', 5-Pentabromodiphenyl ether
notation: BDE99
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

Monthly Income Less Than $416
notation: 284
subclass of: Household Income
type: Class
type: QualityValue

Annual Income $30,001 to $50,000
notation: 162
definition: Personal or family annual income bwtween $30,001 and $50,000
subclass of: Household Income
type: Class
type: QualityValue

terabyte
notation: TB
type: SIO_000074

milligram per deciliter
notation: mg/dl
type: SIO_000074

Mitest not capped
subclass of: SIO_001167
type: Class

millivolt
notation: mV
type: SIO_000074

watt
notation: watt
type: SIO_000074

mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
notation: MEHHTP

Never Married
notation: 38
definition: Indicates a person who has never been married or whose marriages have been annulled.
subclass of: Unmarried
type: Class
type: QualityValue

Spanish Language
notation: 244
definition: The Spanish Language
subclass of: Acculturation
type: Class
type: QualityValue

N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
notation: VOCDHB
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Dietary Intake
definition: The attribute of eating some food.
subclass of: SIO_001105
subclass of: Diet Quantity
type: Class
type: QualityVariable

Light Bulb Count
definition: Total Number of Lightbulbs in the Home
subclass of: SIO_000794
subclass of: Housing Characteristic
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

2, 3, 5, 6-Tetrachlorophenol
notation: TeCP2356
definition: PHYSICAL DESCRIPTION: Leaflets (from ligroin) or light beige powder. (NTP, 1992)
subclass of: Environmental Phenol
type: Class

2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
notation: PBB153
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

3-hydroxybenzo[c]-phenanthrene
notation: BCP3
subclass of: PAH
type: Class

lumen
notation: lm
type: SIO_000074

Consumption Behavior
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: Class
type: QualityVariable

Biological Sex
subclass of: Demographic
type: Class
type: QualityVariable

Asthma Controller Medication Prescription
definition: A subclass of medical intervention that characterizes a patient's receipt of asthma controller medication by prescription. It does not indicate if a patient has or has not received such medication or a prescription for such medication. These distinctions are made in the subclasses of this class.
subclass of: SIO_001398
subclass of: Prescription Medication and Dietary Supplements
type: Class
type: QualityVariable

No FOL result; FOL = 8 ng/mL assumed
subclass of: SIO_001167
type: Class

Neptunium
notation: Np
definition: Neptunium. A radioactive element of the actinide metals family. NEPTUNIUM has the atomic symbol Np, atomic number 93, and atomic weight 237.
subclass of: Metal
type: Class

pneumonia
notation: 195
subclass of: DOID 850
type: Class
type: QualityValue

Operating Room
notation: 171
definition: A room in a health care facility equipped for the performance of surgical operations and procedures.
subclass of: Destination
type: Class
type: QualityValue

Interleukin-22
notation: IL22
subclass of: Protein
type: Class

Widowed
notation: 39
definition: Indicates a person who is no longer married because of the death of his/her spouse and has not remarried.
subclass of: Unmarried
type: Class
type: QualityValue

N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
notation: VOCHEM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Limit of Detection
definition: The lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.
subclass of: Concentration
type: Class

3-hydroxychrysene
notation: CHRY3
subclass of: PAH
type: Class

Has Received Asthma Controller Medication
notation: 283
subclass of: Asthma Controller Medication Prescription
type: Class
type: QualityValue

Eats Rice
notation: 224
definition: The attribute of eating rice.
subclass of: Dietary Intake
subclass of: Restriction
  some values from: FOODON_03301641
  on property: SIO SIO 000369
type: Class
type: QualityValue

2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
notation: BDE153
editorial note: To Do: align with CHEBI.
subclass of: Polybrominated Diphenyl Ether
type: Class

cells per milliliter
notation: cells per ml
type: SIO_000074

Neighborhood Characteristic
definition: Neighborhood Characteristic Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Plutonium
notation: Pu
definition: Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
subclass of: Metal
type: Class

Malaria
notation: 121
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
subclass of: SIO_010299
subclass of: Health Outcome
type: Class
type: QualityValue

parasites per microgram
notation: parasites/µL
type: SIO_000074

megakaryocyte-erythroid progenitor cell

N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
notation: VOCPMM
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

Quit Smoking Before Pregnancy
notation: 81
definition: A Previous Smoker who Quit Smoking Before Pregnancy
subclass of: Quit Smoking
subclass of: Prenatal Nonsmoker
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

Annual Income More Than $100,000
notation: 223
subclass of: Annual Income More Than $95,000
subclass of: Annual Income More Than $70,001
subclass of: Household Income
type: Class
type: QualityValue

Intelligence Quotient
definition: A measure of intelligence
subclass of: SIO_000052
subclass of: Physical And Mental Assessment
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

1-hydroxybenzo[c]-phenanthrene
notation: BCP1
subclass of: PAH
type: Class

Omalizumab (Xolair)
subclass of: Asthma Controller Medication
type: Class

millimole per liter
notation: mmol/L
type: SIO_000074

Specimen analyzed with less than usual dilution
subclass of: SIO_001167
type: Class

Polychlorobiphenyl
subclass of: Organochlorine Compound
type: Class

Study Site
definition: A facility in which study/protocol activities are conducted. [def-source: NCI]
type: QualityVariable

Married
notation: 37
definition: Indicates a person currently joined in a legally binding matrimonial union. Classify common law marriage as married. Includes married couples living together and not living together.
subclass of: Marital Status
type: Class
type: QualityValue

Zafirlukast (Accolate)
subclass of: Asthma Controller Medication
type: Class

micromole per liter
notation: µmol/L
type: SIO_000074

N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
notation: VOCMB2
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

katal per liter
notation: kat/l
type: SIO_000074

Landfill Proximity
definition: How close a household is to a landfill.
subclass of: SIO_000041
subclass of: Environmental Exposure
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

2-hydroxybenzo[c]-phenanthrene
notation: BCP2
subclass of: PAH
type: Class

Difference of Weight-to-Length Z-Scores from 0 to 6 Months
definition: The arithmetic difference between the weight-to-length Z-scores for a child taken at birth and at six months.
subclass of: Difference of Z-Scores
type: Class
type: QualityVariable

milligram per gram
notation: mg/g
type: SIO_000074

Specimen analyzed with less than normal quantity
subclass of: SIO_001167
type: Class

katal per cubic meter
notation: kat/m3
type: SIO_000074

Childhood Followup 2
definition: A point in a study that occurs after the initial follow-up point in the study and occurs during the study subject's childhood period.
subclass of: SIO_000417
subclass of: Study Followup
subclass of: Restriction
  on property: inRelationTo
  all values from: Class
    intersection of: Childhood Period
type: Class

Medical Leave
notation: 246
subclass of: Occupation
type: Class
type: QualityValue

Breath

Measurement
subclass of: Physical And Mental Assessment
type: Class
type: QualityVariable

Health Maintenance Organization Insurance
notation: 49
subclass of: Insurance
type: Class
type: QualityValue

arachidonic acid
notation: C204N6
definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
subclass of: Fatty Acid
type: Class

Hydroxycotinine (total)
notation: HCOTT
notation: HCOT
subclass of: Tobacco Metabolite
label: Hydroxycotinine
type: Class

High Performance Liquid Chromatography - Tandem Mass Spectrometer
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS (Tandem MS) is the combination of two mass analyzers in one mass spec instrument.
subclass of: Liquid Chromatography - Tandem Mass Spectrometer
subclass of: High-Performance Liquid Chromatography-Mass Spectrometry
was approved by: PER-Jim-McCusker
type: Class

Mono-n-pentyl phthalate
notation: MPP
editorial note: Duplicate of mPeP?
subclass of: Phthalate
type: Class

milliliter per liter
notation: ml/l
type: SIO_000074

In Vitro Fertilization
notation: 50
subclass of: Assisted Reproductive Therapy
type: Class
type: QualityValue

Annual Income $30,000 to $49,999
notation: 221
subclass of: Household Income
type: Class
type: QualityValue

Microplate Reader
definition: Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 6-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 µL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 µL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.
subclass of: PhysicalInstrument
was approved by: PER-Jim-McCusker
type: Class

mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
notation: MECPTP

Surface-Induced Dissociation (SID)
subclass of: TandemMassSpectrometry
type: Class

Body Mass Index
editorial note: Should we note that this is derived from height and weight? JS: I think so
definition: A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length
subclass of: SIO_000052
subclass of: Anthropometry
subclass of: Class
  intersection of: Restriction
    some values from: Height
    on property: wasDerivedFrom
  intersection of: Restriction
    some values from: SIO_000279
    on property: wasDerivedFrom
was approved by: PER-Jeanette-Stingone
type: Class
type: QuantityVariable

Quit Smoking After Pregnancy
notation: 80
definition: Quit Smoking After Pregnancy
subclass of: Quit Smoking
subclass of: Prenatal Smoker
subclass of: Pregnancy Characteristic
type: Class
type: QualityValue

Nornicotine
notation: NORN
subclass of: Tobacco Metabolite
type: Class

N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
notation: VOCMB1
editorial note: To Do: align with CHEBI.
subclass of: Volatile Organic Compound
type: Class

milliliter per cubic meter
notation: ml/m3
type: SIO_000074

Insurance
subclass of: Socioeconomic Status
subclass of: Healthcare Access
type: Class
type: QualityVariable

1-hydroxybenz[a]anthacene
notation: BAA1
editorial note: Only found in one journal article, no where else. Maybe mis-spelled?
subclass of: PAH
type: Class

Medical History
definition: Medical History Indicator Class
subclass of: StudyIndicator
was approved by: PER-Jeanette-Stingone
type: Class

Annual Income $50,000 to $99,999
notation: 222
subclass of: Household Income
type: Class
type: QualityValue

million parts per microgram
notation: x106 µL
type: SIO_000074

Study Baseline
definition: Point in study set to initial point.
subclass of: SIO_000417
type: Class

Niobium
notation: Nb
definition: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
subclass of: Metal
type: Class

Autism Spectrum Disorder related condition
notation: 150
definition: Quality refers to children who do not meet DSM criteria for ASD but have scores on ADOS and Mullens that suggest related outcome. All potential options seems to fall under this class from the Autism Ontology
subclass of: Developmental Disorder of Mental Health
type: Class
type: QualityValue

experimentally modified cell in vitro
subclass of: Cell
type: Class

mono benzyl phthalate (BzBP)
notation: MBP
subclass of: Phthalate
type: Class

Leptin
definition: Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways.
subclass of: Protein
subclass of: Metabolite
type: Class

rest: nil
first:
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Datatype
with restrictions:
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on datatype: integer

rest:
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  first: Datatype
    with restrictions:
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    on datatype: float
first: Datatype
  on datatype: float

min inclusive: 15

Datatype
with restrictions:
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on datatype: integer

max exclusive: 25

Datatype
with restrictions:
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on datatype: float

Datatype
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on datatype: float

rest: nil
first:
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max exclusive: 18.5

min exclusive: 25.0