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Cette altération peut être causée par une déficience immunitaire congénitale ou acquise, par certains cancers, par des chimiothérapies cytotoxiques, par des traitements immunosuppresseurs, par des modulateurs immunitaires biologiques, par des pathologies chroniques comme le diabète ou la mucoviscidose, ou par des lésions cutanées ou muqueuses d'origine inflammatoire (par exemple colite ulcéreuse) ou traumatiques (par exemple brûlures graves). Les agents d'infections opportunistes peuvent être différents selon la cause d'immunodépression. 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Les infections opportunistes peuvent être des marqueurs de l'immunodépression et peuvent constituer des signes cliniques de certaines déficiences immunitaires spécifiques (par exemple Pneumocystis jirovecii et VIH)."],"label":[],"synonym":[],"obsolete":false,"prefixIRI":null,"subClassOf":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"parents":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"https://data.bioontology.org/metadata/def/prefLabel":["20000235"],"http://purl.bioontology.org/ontology/MDRFRE/SMQ_ALGO":["N"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://bioportal.bioontology.org/ontologies/umls/tui":["T185"],"http://purl.bioontology.org/ontology/MDRFRE/SMQ_LEVEL":["1"],"http://www.w3.org/2004/02/skos/core#notation":["20000235"],"http://purl.bioontology.org/ontology/MDRFRE/SMQ_STATUS":["A"],"http://purl.bioontology.org/ontology/MDRFRE/SMQ_SOURCE":["1) Schreier R. eMedicine [Internet]. Infections in the immunocompromised host. https://emedicine.medscape.com/article/973120-overview. (Accessed 1 August 2019). 2) Winthrop KL, et al. Opportunistic infections and biologic therapies in immune-mediated inflammatory diseases: consensus recommendations for infection reporting during clinical trials and postmarketing surveillance Annals of the Rheumatic Diseases 2015;74:2107-2116. 3) Centers for Disease Control and Prevention. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients, Recommendations of CDC, the Infectious Disease Society of America, and the American Society of Blood and Marrow Transplantation MMWR. 2000 Oct 20; 49 (RR10): 1-128. 4) Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007 Dec 20; 357: 2601-2614. doi: 10.1056/NEJMra064928. 5) Tomblyn M et al. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Bio Bone Marrow Transplant. 2009 Oct; 15, (10): 1143-238. doi: 10.1016/j.bbmt.2009.06.019. 6) U.S. Department of Health and Human Services [Internet]. Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/0. (Accessed 1 August 2019)."],"http://bioportal.bioontology.org/ontologies/umls/hasSTY":["http://purl.bioontology.org/ontology/STY/T185"],"http://bioportal.bioontology.org/ontologies/umls/cui":["C5244072"],"http://www.w3.org/2004/02/skos/core#prefLabel":["Infections opportunistes (SMQ)"],"http://www.w3.org/2004/02/skos/core#definition":["Une infection opportuniste est une infection causée par un organisme qui ne provoque habituellement pas de maladie chez des sujets ayant un système immunitaire intact, mais qui devient pathogène chez des hôtes immunodéprimés. 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