{"id":"http://purl.bioontology.org/ontology/MEDDRA/20000135","notation":"20000135","semanticType":["http://purl.bioontology.org/ontology/STY/T185"],"cui":["C1964004"],"prefLabel":"Accidents and injuries (SMQ)","definition":["Accidents and injuries have been associated with use of medications, particularly older psychotropic medications, and especially patients with pre-existing high risk levels and/or continuing mental problems. In a study of falls in elderly, use of certain drugs (benzodiazepines, phenothiazines, and antidepressants) was an independent risk factor. Study on risk of accidental injury and benzodiazepines also confirmed an increased risk, especially in patients who had recently filled their prescription. \"Accident\" is defined as \"an unplanned or unintended but sometimes predictable event leading to injury, e.g., in traffic, industry, or a domestic setting, or such an event developing in the course of a disease.\" In medicine, the term \"injury\" can have a very broad meaning. For the purpose of this SMQ, a more narrow definition is used, i.e., \"to injure\" is \"to wound, hurt or harm\". Focus of this SMQ is not on \"metabolic\" injury (toxicity, etc.), but on personal injury or accident to the individual as a result of altered perception, consciousness, attention, behavior, etc."],"label":[],"synonym":[],"obsolete":false,"prefixIRI":null,"subClassOf":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"parents":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://purl.bioontology.org/ontology/MEDDRA/SMQ_STATUS":["A"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://bioportal.bioontology.org/ontologies/umls/tui":["T185"],"http://www.w3.org/2004/02/skos/core#notation":["20000135"],"http://purl.bioontology.org/ontology/MEDDRA/SMQ_LEVEL":["1"],"http://bioportal.bioontology.org/ontologies/umls/hasSTY":["http://purl.bioontology.org/ontology/STY/T185"],"http://purl.bioontology.org/ontology/MEDDRA/SMQ_ALGO":["N"],"http://purl.bioontology.org/ontology/MEDDRA/SOS":["NOTE: Several specific terms pertaining to hemorrhage and hematoma were originally included in this SMQ because they were found to be useful in the identification of cases relevant to Accidents and injuries (SMQ). However, these conditions may result from multiple etiologies, including, but not limited to injury. In addition to the selected hemorrhage terms in this SMQ, this note is included to remind the user that Haemorrhages (SMQ) may also be useful in identifying potential reports of accidents and injuries. NOTE: Currently, many MedDRA PTs have dual links to groupings in SOC Injury, poisoning and procedural complications and groupings in \"disorder\" SOCs, implying that the terms can represent either metabolic or traumatic injury. This needs to be borne in mind when reviewing cases retrieved by this SMQ."],"http://bioportal.bioontology.org/ontologies/umls/cui":["C1964004"],"http://www.w3.org/2004/02/skos/core#prefLabel":["Accidents and injuries (SMQ)"],"http://purl.bioontology.org/ontology/MEDDRA/SMQ_SOURCE":["Wadsworth, EJK, Moss, SC, Simpson, SA, and Smith, AP. Psychotropic medication use and accidents, injuries and cognitive failures. Hum Psychopharmacol Clin Exp 2005; 20: 391-400; Tinetti, ME, Speechley, M, and Ginter, SF. Risk factors for falls among elderly persons living in the community. N Engl J Med 1988; 319(26): 1701-1707; Oster, G, Huse, DM, Adams, SF, Imbimbo, J, and Russell, MW. Benzodiazepine tranquilizers and the risk of accidental injury. Am J Public Health 1990; 80: 1467-1470; Stedman's Medical Dictionary, 27th edition, 2000"],"http://www.w3.org/2004/02/skos/core#definition":["Accidents and injuries have been associated with use of medications, particularly older psychotropic medications, and especially patients with pre-existing high risk levels and/or continuing mental problems. In a study of falls in elderly, use of certain drugs (benzodiazepines, phenothiazines, and antidepressants) was an independent risk factor. 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