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This imbalance can occur when there is an increased amount of the material in the urine, a reduced amount of liquid urine, or a combination of both.~People are most likely to develop kidney stones between ages 40 and 60, though the stones can appear at any age. Research shows that 35 to 50 percent of people who have one kidney stone will develop additional stones, usually within 10 years of the first stone.","<p>A kidney stone is a solid piece of material that forms in the kidney from substances in the urine. It may be as small as a grain of sand or as large as a pearl. Most kidney stones pass out of the body without help from a doctor. But sometimes a stone will not go away. It may get stuck in the urinary tract, block the flow of urine and cause great pain. </p> <p>The following may be signs of kidney stones that need a doctor's help:</p> <ul> <li> Extreme pain in your back or side that will not go away</li> <li> Blood in your urine</li> <li> Fever and chills</li> <li> Vomiting</li> <li> Urine that smells bad or looks cloudy</li> <li> A burning feeling when you urinate</li> </ul> <p>Your doctor will diagnose a kidney stone with urine, blood, and imaging <a href=\"https://medlineplus.gov/kidneytests.html\">tests</a>.</p> <p>If you have a stone that won't pass on its own, you may need treatment. 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