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By holding SRCs in the cytoplasm, SIP prevents these proteins from entering the nucleus to activate genes. In this way, SIP helps to control gene activity.~SIP is found in many organs and tissues, including the skin and kidneys. Little is known about its specific roles in various parts of the body."],"label":[],"obsolete":false,"prefixIRI":null,"subClassOf":[],"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"parents":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://www.w3.org/2004/02/skos/core#altLabel":["SRC-1 interacting protein","ANKRD25","PPKWH","KANK2","matrix-remodelling associated 3","MXRA3","ankyrin repeat domain 25","SIP","KIAA1518","matrix-remodeling-associated protein 3","SRC-interacting protein","SRC1-interacting protein","ankyrin repeat domain-containing protein 25","kidney ankyrin repeat-containing protein 2","SRC-1-interacting protein"],"http://purl.bioontology.org/ontology/MEDLINEPLUS/DB_XR_ID":["NCBI Gene:25959~OMIM:614610"],"http://purl.bioontology.org/ontology/MEDLINEPLUS/has_associated_condition":["http://purl.bioontology.org/ontology/MEDLINEPLUS/C4706686"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://bioportal.bioontology.org/ontologies/umls/tui":["T028"],"http://www.w3.org/2004/02/skos/core#notation":["C1428829"],"http://bioportal.bioontology.org/ontologies/umls/hasSTY":["http://purl.bioontology.org/ontology/STY/T028"],"http://bioportal.bioontology.org/ontologies/umls/cui":["C1428829"],"http://www.w3.org/2004/02/skos/core#prefLabel":["KN motif and ankyrin repeat domains 2"],"http://www.w3.org/2004/02/skos/core#definition":["The KANK2 gene provides instructions for making a protein called SRC-interacting protein (SIP). 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