{"id":"http://purl.bioontology.org/ontology/MESH/D000086969","synonym":["Positive Strand RNA Virus Replication Transcription Complexes","Virus-Induced Double-Membrane Vesicle","Coronavirus Replication-Transcription Compartment","Replication Compartments, Virus","Double-Membrane Vesicles, Virus-Induced","Virus Induced Double Membrane Vesicles","Double Membrane Vesicles, Virus Induced","Coronavirus Double-Membrane Vesicle","Viral Replication Center","Replication Center, Viral","Vesicles, Virus-Induced Double-Membrane","Coronavirus Double-Membrane Vesicles","Double-Membrane Vesicle, Virus-Induced","Coronavirus Replication Transcription Complexes","Double-Membrane Vesicle, Coronavirus","Positive-Strand RNA Virus Replication-Transcription Compartments","Viral Replication Centers","Coronavirus Replication-Transcription Complexes","Complexe, Coronavirus Replication-Transcription","Viral Factory","Replication-Transcription Compartments, Coronavirus","Coronavirus RTCs","Coronavirus Replication-Transcription Compartments","Virus Factories","Replication Compartment, Virus","Vesicle, Coronavirus Double-Membrane","Replication-Transcription Compartment, Coronavirus","Coronavirus Double Membrane Vesicles","Replication-Transcription Complexes, Coronavirus","Replication Compartment, Viral","Vesicle, Virus-Induced Double-Membrane","Complexes, Coronavirus Replication-Transcription","Coronavirus RTC","Viroplasm","Positive Strand RNA Virus Replication-Transcription Complexes","Virus Replication Centers","Virus Replication Compartment","Coronavirus Replication Transcription Compartments","Virus-Induced Double-Membrane Vesicles","Virus Replication Center","Viral Factories","Replication Compartments, Viral","Double-Membrane Vesicles, Coronavirus","Virus Factory","Zippered Endoplasmic Reticulum Double Membrane Spherules","Virus Replication Compartments","Viral Replication Compartment","Replication Centers, Virus","Virogenic Stroma","Replication Center, Virus","Vesicles, Coronavirus Double-Membrane","Replication Centers, Viral","Zippered Endoplasmic Reticulum Double-Membrane Spherules","Positive Strand RNA Virus Replication Transcription Compartments"],"notation":"D000086969","semanticType":["http://purl.bioontology.org/ontology/STY/T026"],"cui":["C5392158","C5392876","C5392875","C5392877","C4083021","C3820746","C5392874","C5392159"],"prefLabel":"Viral Replication Compartments","definition":["Sites in the host cell where the virus induces the formation of cellular assemblies for the replication of the VIRAL GENOME.","Cytoplasmic, virus-induced membrane structures, derived from host cell organelles, that house the replication and transcription enzyme complexes of POSITIVE-STRAND RNA VIRUSES.","Cytoplasmic, virus-induced double-membrane structures, derived from ENDOPLASMIC RETICULUM or GOLGI APPARATUS, that house the replication and transcription enzyme complexes of NIDOVIRALES and PICORNAVIRIDAE.","Double-membrane vesicles that are interconnected by their outer membranes and where coronavirus transcription and replication occur. They are derived from and contiguous with the ENDOPLASMIC RETICULUM.","Subnuclear compartments formed from a reorganization of the nuclear architecture induced by BACULOVIRUSES."],"subClassOf":["http://purl.bioontology.org/ontology/MESH/D007181"],"parents":[{"id":"http://purl.bioontology.org/ontology/MESH/D007181","synonym":["Bodies, Negri","Viral Inclusion Bodies","Bodies, Viral Inclusion","Viral Inclusion Body","Negri Body","Body, Negri","Body, Viral Inclusion","Inclusion Body, Viral","Negri Bodies"],"notation":"D007181","semanticType":["http://purl.bioontology.org/ontology/STY/T026"],"cui":["C0021158","C0242351"],"prefLabel":"Inclusion Bodies, Viral","definition":["An area showing altered staining behavior in the nucleus or cytoplasm of a virus-infected cell. Some inclusion bodies represent virus factories in which viral nucleic acid or protein is being synthesized; others are merely artifacts of fixation and staining. One example, Negri bodies, are found in the cytoplasm or processes of nerve cells in animals that have died from rabies."],"subClassOf":["http://purl.bioontology.org/ontology/MESH/D002479","http://purl.bioontology.org/ontology/MESH/D018406"],"label":[],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"obsolete":false,"prefixIRI":null,"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://purl.bioontology.org/ontology/MESH/D007181","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181","ontology":"https://data.bioontology.org/ontologies/MESH","children":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/children","parents":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/parents","descendants":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/descendants","ancestors":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/ancestors","instances":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/instances","tree":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/tree","notes":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/notes","mappings":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181/mappings","ui":"http://bioportal.bioontology.org/ontologies/MESH?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD007181","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"label":[],"obsolete":false,"prefixIRI":null,"xref":null,"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[null],"isInActiveCollection":[],"properties":{"http://www.w3.org/2004/02/skos/core#altLabel":["Positive Strand RNA Virus Replication Transcription Complexes","Virus-Induced Double-Membrane Vesicle","Coronavirus Replication-Transcription Compartment","Replication Compartments, Virus","Double-Membrane Vesicles, Virus-Induced","Virus Induced Double Membrane Vesicles","Double Membrane Vesicles, Virus Induced","Coronavirus Double-Membrane Vesicle","Viral Replication Center","Replication Center, Viral","Vesicles, Virus-Induced Double-Membrane","Coronavirus Double-Membrane Vesicles","Double-Membrane Vesicle, Virus-Induced","Coronavirus Replication Transcription Complexes","Double-Membrane Vesicle, Coronavirus","Positive-Strand RNA Virus Replication-Transcription Compartments","Viral Replication Centers","Coronavirus Replication-Transcription Complexes","Complexe, Coronavirus Replication-Transcription","Viral Factory","Replication-Transcription Compartments, Coronavirus","Coronavirus RTCs","Coronavirus Replication-Transcription Compartments","Virus Factories","Replication Compartment, Virus","Vesicle, Coronavirus Double-Membrane","Replication-Transcription Compartment, Coronavirus","Coronavirus Double Membrane Vesicles","Replication-Transcription Complexes, Coronavirus","Replication Compartment, Viral","Vesicle, Virus-Induced Double-Membrane","Complexes, Coronavirus Replication-Transcription","Coronavirus RTC","Viroplasm","Positive Strand RNA Virus Replication-Transcription Complexes","Virus Replication Centers","Virus Replication Compartment","Coronavirus Replication Transcription Compartments","Virus-Induced Double-Membrane Vesicles","Virus Replication Center","Viral Factories","Replication Compartments, Viral","Double-Membrane Vesicles, Coronavirus","Virus Factory","Zippered Endoplasmic Reticulum Double Membrane Spherules","Virus Replication Compartments","Viral Replication Compartment","Replication Centers, Virus","Virogenic Stroma","Replication Center, Virus","Vesicles, Coronavirus Double-Membrane","Replication Centers, Viral","Zippered Endoplasmic Reticulum Double-Membrane Spherules","Positive Strand RNA Virus Replication Transcription Compartments"],"http://purl.bioontology.org/ontology/MESH/PM":["2021"],"http://purl.bioontology.org/ontology/MESH/HN":["2021"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://bioportal.bioontology.org/ontologies/umls/tui":["T026"],"http://purl.bioontology.org/ontology/MESH/TERMUI":["T001081375","T001081378","T001081383","T001081382","T001080920","T001081427","T001081379","T001081374","T001080919","T001081431","T001080905","T001081372","T001083208","T001081373","T001081377","T001081430","T001080921","T001081376","T001080906"],"http://purl.bioontology.org/ontology/MESH/TH":["NLM (2021)"],"http://purl.bioontology.org/ontology/MESH/MMR":["20210101"],"http://www.w3.org/2004/02/skos/core#notation":["D000086969"],"http://purl.bioontology.org/ontology/MESH/RO":["http://purl.bioontology.org/ontology/MESH/D014779"],"http://bioportal.bioontology.org/ontologies/umls/hasSTY":["http://purl.bioontology.org/ontology/STY/T026"],"http://purl.bioontology.org/ontology/MESH/QB":["http://purl.bioontology.org/ontology/MESH/Q000648","http://purl.bioontology.org/ontology/MESH/Q000276","http://purl.bioontology.org/ontology/MESH/Q000378","http://purl.bioontology.org/ontology/MESH/Q000473","http://purl.bioontology.org/ontology/MESH/Q000145","http://purl.bioontology.org/ontology/MESH/Q000737","http://purl.bioontology.org/ontology/MESH/Q000502","http://purl.bioontology.org/ontology/MESH/Q000187","http://purl.bioontology.org/ontology/MESH/Q000201","http://purl.bioontology.org/ontology/MESH/Q000528"],"http://purl.bioontology.org/ontology/MESH/FX":["D014779"],"http://purl.bioontology.org/ontology/MESH/DX":["20210101"],"http://bioportal.bioontology.org/ontologies/umls/cui":["C5392158","C5392876","C5392875","C5392877","C4083021","C3820746","C5392874","C5392159"],"http://www.w3.org/2004/02/skos/core#prefLabel":["Viral Replication Compartments"],"http://purl.bioontology.org/ontology/MESH/DC":["1"],"http://www.w3.org/2004/02/skos/core#definition":["Sites in the host cell where the virus induces the formation of cellular assemblies for the replication of the VIRAL GENOME.","Cytoplasmic, virus-induced membrane structures, derived from host cell organelles, that house the replication and transcription enzyme complexes of POSITIVE-STRAND RNA VIRUSES.","Cytoplasmic, virus-induced double-membrane structures, derived from ENDOPLASMIC RETICULUM or GOLGI APPARATUS, that house the replication and transcription enzyme complexes of NIDOVIRALES and PICORNAVIRIDAE.","Double-membrane vesicles that are interconnected by their outer membranes and where coronavirus transcription and replication occur. They are derived from and contiguous with the ENDOPLASMIC RETICULUM.","Subnuclear compartments formed from a reorganization of the nuclear architecture induced by BACULOVIRUSES."],"http://purl.bioontology.org/ontology/MESH/MN":["G06.920.400.500","A11.284.420.390.500"],"http://purl.bioontology.org/ontology/MESH/AQL":["CH CL DE EN IM ME PA PH RE UL"],"http://purl.bioontology.org/ontology/MESH/MDA":["20200518"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://purl.bioontology.org/ontology/MESH/D007181"]},"@id":"http://purl.bioontology.org/ontology/MESH/D000086969","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969","ontology":"https://data.bioontology.org/ontologies/MESH","children":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/children","parents":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/parents","descendants":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/descendants","ancestors":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/ancestors","instances":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/instances","tree":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/tree","notes":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/notes","mappings":"https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969/mappings","ui":"http://bioportal.bioontology.org/ontologies/MESH?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD000086969","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}