{

• "id": "http://purl.bioontology.org/ontology/MESH/D017403",
• "prefLabel": "In Situ Hybridization",
• -
  "synonym": [
  • "Hybridizations, In Situ",
  • "Hybridization, In Situ",
  • "In Situ Hybridizations",
  • "Hybridization in Situ"
  ],
• -
  "definition": [
  • "A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes."
  ],
• -
  "cui": [
  • "C0162788"
  ],
• -
  "semanticType": [
  • "http://purl.bioontology.org/ontology/STY/T063"
  ],
• "obsolete": false,
• -
  "parents": [
  • -
    {
    • "id": "http://purl.bioontology.org/ontology/MESH/D013194",
    • "prefLabel": "Staining and Labeling",
    • -
      "synonym": [
      • "Staining",
      • "Histological Labeling",
      • "Labeling and Staining",
      • "Histological Labelings",
      • "Labeling, Histological",
      • "Labelings, Histological",
      • "Stainings"
      ],
    • -
      "definition": [
      • "The use of a dye, reagent, or other material for producing coloration or contrast in biological materials for examination or observation.",
      • "The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts."
      ],
    • -
      "cui": [
      • "C0887853",
      • "C0886517",
      • "C0487602"
      ],
    • -
      "semanticType": [
      • "http://purl.bioontology.org/ontology/STY/T059"
      ],
    • "obsolete": false,
    • -
      "subClassOf": [
      • "http://purl.bioontology.org/ontology/MESH/D016591"
      ],
    • "label": [ ],
    • "prefixIRI": null,
    • "notation": "D013194",
    • "xref": null,
    • "created": null,
    • "modified": null,
    • "@id": "http://purl.bioontology.org/ontology/MESH/D013194",
    • "@type": "http://www.w3.org/2002/07/owl#Class",
    • -
      "links": {
      • "self": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194",
      • "ontology": "https://data.bioontology.org/ontologies/MESH",
      • "children": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/children",
      • "parents": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/parents",
      • "descendants": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/descendants",
      • "ancestors": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/ancestors",
      • "instances": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/instances",
      • "tree": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/tree",
      • "notes": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/notes",
      • "mappings": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194/mappings",
      • "ui": "http://bioportal.bioontology.org/ontologies/MESH?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD013194",
      • -
        "@context": {
        • "self": "http://www.w3.org/2002/07/owl#Class",
        • "ontology": "http://data.bioontology.org/metadata/Ontology",
        • "children": "http://www.w3.org/2002/07/owl#Class",
        • "parents": "http://www.w3.org/2002/07/owl#Class",
        • "descendants": "http://www.w3.org/2002/07/owl#Class",
        • "ancestors": "http://www.w3.org/2002/07/owl#Class",
        • "instances": "http://data.bioontology.org/metadata/Instance",
        • "tree": "http://www.w3.org/2002/07/owl#Class",
        • "notes": "http://data.bioontology.org/metadata/Note",
        • "mappings": "http://data.bioontology.org/metadata/Mapping",
        • "ui": "http://www.w3.org/2002/07/owl#Class"
        }
      },
    • -
      "@context": {
      • "@vocab": "http://data.bioontology.org/metadata/",
      • "label": "http://www.w3.org/2000/01/rdf-schema#label",
      • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
      • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
      • "definition": "http://www.w3.org/2004/02/skos/core#definition",
      • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
      • "notation": "http://www.w3.org/2004/02/skos/core#notation",
      • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
      • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
      • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
      • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
      • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      • "created": "http://purl.org/dc/terms/created",
      • "modified": "http://purl.org/dc/terms/modified",
      • "@language": "en"
      }
    },
  • -
    {
    • "id": "http://purl.bioontology.org/ontology/MESH/D009693",
    • "prefLabel": "Nucleic Acid Hybridization",
    • -
      "synonym": [
      • "Hybridizations, Genomic",
      • "Hybridization, Genomic",
      • "Acid Hybridization, Nucleic",
      • "Hybridizations, Nucleic Acid",
      • "Acid Hybridizations, Nucleic",
      • "Genomic Hybridization",
      • "Hybridization, Nucleic Acid",
      • "Nucleic Acid Hybridizations",
      • "Genomic Hybridizations"
      ],
    • -
      "definition": [
      • "Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)"
      ],
    • -
      "cui": [
      • "C0376343",
      • "C1300517"
      ],
    • -
      "semanticType": [
      • "http://purl.bioontology.org/ontology/STY/T059",
      • "http://purl.bioontology.org/ontology/STY/T070"
      ],
    • "obsolete": false,
    • -
      "subClassOf": [
      • "http://purl.bioontology.org/ontology/MESH/D001669",
      • "http://purl.bioontology.org/ontology/MESH/D005821"
      ],
    • "label": [ ],
    • "prefixIRI": null,
    • "notation": "D009693",
    • "xref": null,
    • "created": null,
    • "modified": null,
    • "@id": "http://purl.bioontology.org/ontology/MESH/D009693",
    • "@type": "http://www.w3.org/2002/07/owl#Class",
    • -
      "links": {
      • "self": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693",
      • "ontology": "https://data.bioontology.org/ontologies/MESH",
      • "children": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/children",
      • "parents": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/parents",
      • "descendants": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/descendants",
      • "ancestors": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/ancestors",
      • "instances": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/instances",
      • "tree": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/tree",
      • "notes": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/notes",
      • "mappings": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693/mappings",
      • "ui": "http://bioportal.bioontology.org/ontologies/MESH?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD009693",
      • -
        "@context": {
        • "self": "http://www.w3.org/2002/07/owl#Class",
        • "ontology": "http://data.bioontology.org/metadata/Ontology",
        • "children": "http://www.w3.org/2002/07/owl#Class",
        • "parents": "http://www.w3.org/2002/07/owl#Class",
        • "descendants": "http://www.w3.org/2002/07/owl#Class",
        • "ancestors": "http://www.w3.org/2002/07/owl#Class",
        • "instances": "http://data.bioontology.org/metadata/Instance",
        • "tree": "http://www.w3.org/2002/07/owl#Class",
        • "notes": "http://data.bioontology.org/metadata/Note",
        • "mappings": "http://data.bioontology.org/metadata/Mapping",
        • "ui": "http://www.w3.org/2002/07/owl#Class"
        }
      },
    • -
      "@context": {
      • "@vocab": "http://data.bioontology.org/metadata/",
      • "label": "http://www.w3.org/2000/01/rdf-schema#label",
      • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
      • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
      • "definition": "http://www.w3.org/2004/02/skos/core#definition",
      • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
      • "notation": "http://www.w3.org/2004/02/skos/core#notation",
      • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
      • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
      • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
      • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
      • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
      • "created": "http://purl.org/dc/terms/created",
      • "modified": "http://purl.org/dc/terms/modified",
      • "@language": "en"
      }
    }
  ],
• -
  "subClassOf": [
  • "http://purl.bioontology.org/ontology/MESH/D013194",
  • "http://purl.bioontology.org/ontology/MESH/D009693"
  ],
• "label": [ ],
• "prefixIRI": null,
• "notation": "D017403",
• "xref": null,
• "created": null,
• "modified": null,
• -
  "properties": {
  • -
    "http://purl.bioontology.org/ontology/MESH/TH": [
    • "NLM (1993)"
    ],
  • -
    "http://www.w3.org/2004/02/skos/core#notation": [
    • "D017403"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/DX": [
    • "19930101"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/PM": [
    • "93"
    ],
  • -
    "http://www.w3.org/2004/02/skos/core#altLabel": [
    • "Hybridizations, In Situ",
    • "Hybridization, In Situ",
    • "In Situ Hybridizations",
    • "Hybridization in Situ"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/MN": [
    • "E01.370.225.750.600.670.325",
    • "E05.200.750.600.670.325",
    • "E01.370.225.500.620.670.325",
    • "E05.393.661.475",
    • "E05.200.500.620.670.325"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/MMR": [
    • "20110624"
    ],
  • -
    "http://www.w3.org/2004/02/skos/core#prefLabel": [
    • "In Situ Hybridization"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/AQL": [
    • "AE CL EC ES HI IS MO MT NU PX SN ST TD VE"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/HN": [
    • "93"
    ],
  • -
    "http://www.w3.org/2000/01/rdf-schema#subClassOf": [
    • "http://purl.bioontology.org/ontology/MESH/D013194",
    • "http://purl.bioontology.org/ontology/MESH/D009693"
    ],
  • -
    "http://bioportal.bioontology.org/ontologies/umls/hasSTY": [
    • "http://purl.bioontology.org/ontology/STY/T063"
    ],
  • -
    "http://www.w3.org/2004/02/skos/core#definition": [
    • "A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes."
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/DC": [
    • "1"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/MDA": [
    • "19920520"
    ],
  • -
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#type": [
    • "http://www.w3.org/2002/07/owl#Class"
    ],
  • -
    "http://bioportal.bioontology.org/ontologies/umls/tui": [
    • "T063"
    ],
  • -
    "http://bioportal.bioontology.org/ontologies/umls/cui": [
    • "C0162788"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/AN": [
    • "to locate specific nucleic acid seq"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/QB": [
    • "http://purl.bioontology.org/ontology/MESH/Q000266",
    • "http://purl.bioontology.org/ontology/MESH/Q000379",
    • "http://purl.bioontology.org/ontology/MESH/Q000706",
    • "http://purl.bioontology.org/ontology/MESH/Q000662",
    • "http://purl.bioontology.org/ontology/MESH/Q000009",
    • "http://purl.bioontology.org/ontology/MESH/Q000941",
    • "http://purl.bioontology.org/ontology/MESH/Q000191",
    • "http://purl.bioontology.org/ontology/MESH/Q000145",
    • "http://purl.bioontology.org/ontology/MESH/Q000592",
    • "http://purl.bioontology.org/ontology/MESH/Q000295",
    • "http://purl.bioontology.org/ontology/MESH/Q000451",
    • "http://purl.bioontology.org/ontology/MESH/Q000639",
    • "http://purl.bioontology.org/ontology/MESH/Q000523",
    • "http://purl.bioontology.org/ontology/MESH/Q000401"
    ],
  • -
    "http://purl.bioontology.org/ontology/MESH/TERMUI": [
    • "T052028",
    • "T052029"
    ]
  },
• "@id": "http://purl.bioontology.org/ontology/MESH/D017403",
• "@type": "http://www.w3.org/2002/07/owl#Class",
• -
  "links": {
  • "self": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403",
  • "ontology": "https://data.bioontology.org/ontologies/MESH",
  • "children": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/children",
  • "parents": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/parents",
  • "descendants": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/descendants",
  • "ancestors": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/ancestors",
  • "instances": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/instances",
  • "tree": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/tree",
  • "notes": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/notes",
  • "mappings": "https://data.bioontology.org/ontologies/MESH/classes/http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403/mappings",
  • "ui": "http://bioportal.bioontology.org/ontologies/MESH?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FMESH%2FD017403",
  • -
    "@context": {
    • "self": "http://www.w3.org/2002/07/owl#Class",
    • "ontology": "http://data.bioontology.org/metadata/Ontology",
    • "children": "http://www.w3.org/2002/07/owl#Class",
    • "parents": "http://www.w3.org/2002/07/owl#Class",
    • "descendants": "http://www.w3.org/2002/07/owl#Class",
    • "ancestors": "http://www.w3.org/2002/07/owl#Class",
    • "instances": "http://data.bioontology.org/metadata/Instance",
    • "tree": "http://www.w3.org/2002/07/owl#Class",
    • "notes": "http://data.bioontology.org/metadata/Note",
    • "mappings": "http://data.bioontology.org/metadata/Mapping",
    • "ui": "http://www.w3.org/2002/07/owl#Class"
    }
  },
• -
  "@context": {
  • "@vocab": "http://data.bioontology.org/metadata/",
  • "label": "http://www.w3.org/2000/01/rdf-schema#label",
  • "prefLabel": "http://www.w3.org/2004/02/skos/core#prefLabel",
  • "synonym": "http://www.w3.org/2004/02/skos/core#altLabel",
  • "definition": "http://www.w3.org/2004/02/skos/core#definition",
  • "obsolete": "http://www.w3.org/2002/07/owl#deprecated",
  • "notation": "http://www.w3.org/2004/02/skos/core#notation",
  • "prefixIRI": "http://data.bioontology.org/metadata/prefixIRI",
  • "parents": "http://www.w3.org/2000/01/rdf-schema#parents",
  • "subClassOf": "http://www.w3.org/2000/01/rdf-schema#subClassOf",
  • "semanticType": "http://bioportal.bioontology.org/ontologies/umls/hasSTY",
  • "cui": "http://bioportal.bioontology.org/ontologies/umls/cui",
  • "xref": "http://www.geneontology.org/formats/oboInOwl#hasDbXref",
  • "created": "http://purl.org/dc/terms/created",
  • "modified": "http://purl.org/dc/terms/modified",
  • "@language": "en"
  }

}