The HHEAR Ontology
type: Ontology
version IRI: v1.12
description: The Human Health Exposure Analysis Resource (HHEAR).
license: https://creativecommons.org/licenses/by/4.0/
comment: The Human Health Exposure Analysis Resource (HHEAR) measures exposures that cover the breadth of the “exposome,” which encompasses all environmental exposures including chemical, physical, and biological stressors, as well as lifestyle and social environments, from conception through adulthood. More information is available here: https://hhearprogram.org
label: HHEAR Ontology v1.12

wasDerivedFrom
type: ObjectProperty
domain: Entity
range: Entity
comment: The more specific subproperties of prov:wasDerivedFrom (i.e., prov:wasQuotedFrom, prov:wasRevisionOf, prov:hadPrimarySource) should be used when applicable.

currency
type: DatatypeProperty
comment: The currency in which the monetary amount is expressed.\n\nUse standard formats: [ISO 4217 currency format](http://en.wikipedia.org/wiki/ISO_4217), e.g. "USD"; [Ticker symbol](https://en.wikipedia.org/wiki/List_of_cryptocurrencies) for cryptocurrencies, e.g. "BTC"; well known names for [Local Exchange Trading Systems](https://en.wikipedia.org/wiki/Local_exchange_trading_system) (LETS) and other currency types, e.g. "Ithaca HOUR".

maxValue
type: DatatypeProperty
comment: The upper value of some characteristic or property.

minValue
type: DatatypeProperty
comment: The lower value of some characteristic or property.

Analytical Method
type: Class
subclass of: Thing
comment: This class denotes Analytical Method

Chromatography
type: Class
subclass of: Thing
comment: This class denotes Chromatography

cohort
type: Class
subclass of: Demographic
comment: This class denotes cohort

cohort study
type: Class
subclass of: Thing
comment: This class denotes cohort study

Cross Sectional Study
type: Class
subclass of: SIO_001066

Immunoassay
type: Class
subclass of: Thing
comment: This class denotes Immunoassay

Indicator
type: Class
subclass of: Thing
comment: This class denotes Indicator

Mass Spectrometry
type: Class
subclass of: Thing
comment: This class denotes Mass Spectrometry

Quality Value
type: Class
subclass of: Thing
type: NamedIndividual
type: NodeShape
comment: This class denotes Quality Value

Quality Variable
type: Class
subclass of: Thing
comment: This class denotes Quality Variable

Quantity Variable
type: Class
subclass of: Thing
comment: This class denotes Quantity Variable

Sample Indicator
type: Class
subclass of: Thing
comment: This class denotes Sample Indicator

Science Indicator
type: Class
subclass of: Thing
comment: This class denotes Science Indicator

Spectroscopy
type: Class
subclass of: Thing
comment: This class denotes Spectroscopy

Study Indicator
type: Class
subclass of: Thing
comment: This class denotes Study Indicator

Tandem Mass Spectrometry
type: Class
subclass of: Thing
comment: This class denotes Tandem Mass Spectrometry

Physical Instrument
type: Class
subclass of: Thing
comment: This class denotes Physical Instrument

Questionnaire
type: Class
subclass of: Thing
subclass of: Restriction
  on property: SIO_000059
  some values from: Questionnaire Response
subclass of: Restriction
  on property: SIO_000059
  some values from: SIO_000085
comment: An instrument used to acquire data reported from human subjects.

Administrative Claims, Healthcare
type: Class
subclass of: SIO_001027
type: NamedIndividual
type: NodeShape
comment: Information relating to itemized coding of procedures and costs associated with healthcare delivery, used as a means for tracking healthcare utilization, patterns of care, and treatment outcomes. (Source: Medical Subject Headings Ontology)

Public Assistance
type: Class
subclass of: Socioeconomic Status
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: Financial assistance to impoverished persons for the essentials of living through federal, state or local government programs. (Source: MESH Ontology)

Registeries
type: Class
subclass of: SIO_001052
type: NamedIndividual
type: NodeShape
comment: The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers. (Source: Medical Subject Headings Ontology)

Electronic Health Records
type: Class
subclass of: SIO_001027
type: NamedIndividual
type: NodeShape
comment: Media that facilitate transportability of pertinent information concerning patient's illness across varied providers and geographic locations. Some versions include direct linkages to online CONSUMER HEALTH INFORMATION that is relevant to the health conditions and treatments related to a specific patient. (Source: Medical Subject Headings Ontology)

Crowdsourcing
type: Class
subclass of: SIO_001052
type: NamedIndividual
type: NodeShape
comment: Results of data collected from Crowdsource collection. Social media model for enabling public involvement and recruitment in participation. Use of social media to collect feedback and recruit volunteer subjects. Source: Medical Subject Headings Ontology

Food Assistance
type: Class
subclass of: Public Assistance
type: NamedIndividual
type: NodeShape
comment: United States federal food stamp program, also known as SNAP. Food or financial assistance for food given to those in need. (Source: MESH Ontology)

Theophylline
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Theophylline

trifluridine
type: Class
subclass of: SIO_010039
type: NamedIndividual
type: NodeShape
comment: Trifluridine (also called trifluorothymidine; abbreviation TFT or FTD[1]) is an anti-herpesvirus antiviral drug, used primarily as prescription eyedrops. (Source: https://en.wikipedia.org/wiki/Trifluridine)

Beclomethasone HFA
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Beclomethasone HFA

Ciclesonide HFA (Alvesco)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Ciclesonide HFA (Alvesco)

Flunisolide HFA (Aerospan)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Flunisolide HFA (Aerospan)

Zafirlukast (Accolate)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Zafirlukast (Accolate)

Mometasone HFA (Asmanex HFA)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Mometasone HFA (Asmanex HFA)

Montelukast (Singulair)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Montelukast (Singulair)

Fluticasone/vilanterol (Breo Ellipta)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone/vilanterol (Breo Ellipta)

Fluticasone furoate DPI (Arnuity Ellipta)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone furoate DPI (Arnuity Ellipta)

Budesonide nebulized (Pulmicort)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Budesonide nebulized (Pulmicort)

Zileuton (Zyflo)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Zileuton (Zyflo)

Budesonide/formoterol (Symbicort)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Budesonide/formoterol (Symbicort)

Omalizumab (Xolair)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Omalizumab (Xolair)

Cromolyn
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Cromolyn

Fluticasone propionate HFA (Flovent HFA)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone propionate HFA (Flovent HFA)

Mometasone DPI (Asmanex)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Mometasone DPI (Asmanex)

Fluticasone propionate DPI (Flovent Diskus)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone propionate DPI (Flovent Diskus)

Budesonide DPI (Pulmicort)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Budesonide DPI (Pulmicort)

Fluticasone/salmeterol DPI (Advair Diskus)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone/salmeterol DPI (Advair Diskus)

Fluticasone/salmeterol HFA(Advair HFA)
type: Class
subclass of: Asthma Controller Medication
comment: This class denotes Fluticasone/salmeterol HFA(Advair HFA)

anatomical entity
type: Class
subclass of: Thing
comment: A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. [database_cross_reference: CAROC:Brownsville2014]

beta-cryptoxanthin
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A carotenol that exhibits antioxidant activity. It has been isolated from fruits such as papaya and oranges. (Source: ChEBI)
notation: CRYP

Cis-Nonachlor
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Cis-Nonachlor
notation: CNON

sulfoxaflor
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A mixture of the four diastereoisomers arising from the two tetrahedral stereocentres of [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-λ6-sulfanylidene]cyanamide (the sulfur atom and the carbon attached to position 3 of the pyridine ring). [Both E- and Z-isomers involving the S=N double bond and the cyano group exist, but they interconvert rapidly at r.t.]. A nicotinic acetylcholine receptor agonist in insects, sulfoxaflor is used as an insecticide, particularly for the control of aphids. Source: ChEBI
notation: SUF

Polybrominated Diphenyl Ether
type: Class
subclass of: brominated flame retardant
comment: This class denotes Polybrominated Diphenyl Ether

Volatile Organic Compound
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Volatile Organic Compound
notation: VOCs

Perfluorooctanesulfonamide
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorooctanesulfonamide
notation: PFOSA

isoprostane
type: Class
subclass of: chemical entity
comment: Any icosanoid with a prostaglandin-like structure formed in vivo by non-enzymatic free radical-catalysed reactions involving peroxidation of essential fatty acids (mainly arachidonic acid but also other fatty acids with 3 or more double bonds). Isoprostanes are abundant in tissues and fluids and have immunomodulating activity. Their concentration is dependent on the amount of oxidative stress and may be upregulated in certain diseases such as cancer, cardiovascular and neurological disorders. (Source: CHEBI Ontology)

5-iso Prostaglandin F2 alpha-VI
type: Class
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
comment: This class denotes 5-iso Prostaglandin F2 alpha-VI
notation: F2AVI

leukotriene E4
type: Class
subclass of: Biological Response
subclass of: Inflammatory Marker
type: NamedIndividual
type: Facet Value
comment: This class denotes leukotriene E4
notation: LTE4

hexadecanoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
notation: C160

arachidonic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
notation: C204N6

atrazine
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6 while one of hydrogens of each amino group is replaced respectively by an ethyl and a propan-2-yl group. Source: ChEBI
notation: ATRAZ
notation: ATZ

Ethylbenzene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: Ethylbenzene is mainly used in the manufacture of styrene. Acute (short-term) exposure to ethylbenzene in humans results in respiratory effects, such as throat irritation and chest constriction, irritation of the eyes, and neurological effects such as dizziness. Chronic (long-term) exposure to ethylbenzene by inhalation in humans has shown conflicting results regarding its effects on the blood. Animal studies have reported effects on the blood, liver, and kidneys from chronic inhalation exposure to ethylbenzene. Limited information is available on the carcinogenic effects of ethylbenzene in humans. In a study by the National Toxicology Program (NTP), exposure to ethylbenzene by inhalation resulted in an increased incidence of kidney and testicular tumors in rats, and lung and liver tumors in mice. EPA has classified ethylbenzene as a Group D, not classifiable as to human carcinogenicity.
notation: EB

cholesterol
type: Class
subclass of: Lipid in Blood
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes cholesterol
notation: CHOL

4, 4'-DDT
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes 4, 4'-DDT
notation: PPDDT

oleic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.
notation: C181N9

Triclosan
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: Triclosan is a diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
notation: TCS

Nitric Oxide
type: Class
subclass of: Air Pollutant
comment: This class denotes Nitric Oxide

naphthalene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia. (Source: ChEBI Ontology)
notation: NAP

4-Fluoro-3-phenoxybenzoic acid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes 4-Fluoro-3-phenoxybenzoic acid
notation: FPBA

N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
notation: AAMA

4, 4'-DDE
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes 4, 4'-DDE
notation: PPDDE

Cyclohexane-1,2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes Cyclohexane-1,2-dicarboxylic acid mono carboxyisooctyl ester (DINCH)
notation: MCOCH

Cyclohexane-1,2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes Cyclohexane-1,2-dicarboxylic acid mono hydroxyisononyl ester (DINCH)
notation: MHNCH

Diphenyl Phosphate
type: Class
subclass of: Organophosphorus Flame Retardant
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Diphenyl Phosphate
notation: DPHP

Bis-(1,3-dichloro-2-propyl) phosphate
type: Class
subclass of: Organophosphorus Flame Retardant
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Bis-(1,3-dichloro-2-propyl) phosphate
notation: BDCPP

Benzene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: Toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. It is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. Benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. It was formerly used as parasiticide.
notation: BZ

Creatinine
type: Class
subclass of: Urinary Dilution Factor
type: NamedIndividual
type: Facet Value
definition: Creatinine is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
notation: CRE

2, 4-Dichlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: 2, 4-dichlorophenol is a colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.
notation: DCP24

Inorganic Mercury (Hg2+)
type: Class
subclass of: Mercury Species
comment: This class denotes Inorganic Mercury (Hg2+)
notation: Hg2

dehydroepiandrosterone sulfate
type: Class
subclass of: Biological Response
subclass of: Metabolite
definition: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.

cortisone
type: Class
subclass of: Psychosocial Stress Marker
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes cortisone
notation: CORTE

progesterone
type: Class
subclass of: chemical entity
type: NamedIndividual
type: Quality Value
comment: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
notation: HHEAR_1208

glucose
type: Class
subclass of: Biological Response
subclass of: Metabolite
definition: An aldohexose used as a source of energy and metabolic intermediate.

brominated flame retardant
type: Class
subclass of: flame retardant
type: NamedIndividual
type: Facet
type: NodeShape
comment: Any organobromine compound that is used as a flame retardant. These chemicals are widely incorporated as additives in consumer products such as electronics, vehicles, polyurethane foams etc, to make them less flammable. (Source: CHEBI)
notation: PBFR

mono(2-ethylhexyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: Clear colorless to cloudy white viscous liquid. (NTP, 1992)
notation: MEHP

Tetrachloroethene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: TETRACHLOROETHYLENE is a chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.
notation: TCE

penicillin
type: Class
subclass of: chemical entity
type: NamedIndividual
type: NodeShape
comment: Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6.

linoleic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.
notation: C182N6

Toluene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: Toluene is a widely used industrial solvent.
notation: TOL

beta-carotene
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. (Source: ChEBI)
notation: BCAR

Pentachlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool.
notation: PCP

cortisol
type: Class
subclass of: Psychosocial Stress Marker
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes cortisol
notation: CORTL

bis(2-ethylhexyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: NodeShape
comment: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid. (Source: ChEBI)
notation: DEHP

triglyceride
type: Class
subclass of: Lipid in Blood
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes triglyceride
notation: TG

gamma-tocopherol
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes gamma-tocopherol
notation: GTOC

Manganese
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: MANGANESE is a trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
notation: Mn

tri-2-ethylhexyl trimellitate
type: Class
subclass of: carboxylic ester
type: NamedIndividual
type: NodeShape
comment: CAS: 3319-31-1
notation: TOTM

Nicotine
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
notation: NIC

malathion diacid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes malathion diacid
notation: MDA

2-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-hydroxyphenanthrene
notation: PHEN2

3-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-hydroxyphenanthrene
notation: PHEN3

4-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 4-hydroxyphenanthrene
notation: PHEN4

acenaphthene
type: Class
subclass of: organic polycyclic compound
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: A polycyclic aromatic hydrocarbon derived from naphthalene by the addition of an ethylene bridge connecting C-1 and C-8. (Source: ChEBI Ontology)
notation: ACEN

Benzophenone
type: Class
subclass of: Phenol
comment: This class denotes Benzophenone

Cadmium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: An element with atomic symbol Cd, atomic number 48, and atomic weight 114. It is a metal and ingestion will lead to CADMIUM POISONING.
notation: Cd

cyclic peptide
type: Class
subclass of: Biological Response
subclass of: Metabolite
definition: A molecular entity capable of accepting a hydron from a donor (Bronsted acid).

diazole
type: Class
subclass of: Thing
comment: This class denotes diazole

drug
type: Class
subclass of: Thing
comment: Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. (Source: CHEBI Ontology)

chemical entity
type: Class
subclass of: Entity
comment: A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. (Source: CHEBI Ontology)

organic heterocyclic compound
type: Class
subclass of: Thing
comment: This class denotes organic heterocyclic compound

hormone
type: Class
subclass of: molecular messenger
subclass of: agonist
comment: This class denotes hormone

Lead
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: LEAD is a soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.19, symbol Pb. (Dorland, 28th)
notation: Pb

Magnesium
type: Class
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: An element with atomic symbol Mg, atomic number 12, and atomic weight 24.3. Magnesium is an alkaline earth metal and is important to bone structure in human physiology.
notation: Mg

Mercury
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
notation: Hg

albuterol
type: Class
subclass of: chemical entity
subclass of: Asthma Controller Medication
type: NamedIndividual
type: NodeShape
comment: A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a β-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Ozone
type: Class
subclass of: Air Pollutant
comment: This class denotes Ozone

Pesticide
type: Class
subclass of: SIO_011126
type: NamedIndividual
type: NodeShape
comment: Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. (Source: ChEBI Ontology)

Phthalate
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Phthalate
notation: UPHTH

amoxicillin
type: Class
subclass of: chemical entity
type: NamedIndividual
type: NodeShape
comment: A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group.

Tin
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: TIN is a trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
notation: Sn

toxin
type: Class
subclass of: Thing
comment: Poisonous substance produced by a biological organism such as a microbe, animal or plant. (Source: CHEBI Ontology)

Anatabine
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes Anatabine
notation: ANAT

Trimethylarsine oxide
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
comment: This class denotes Trimethylarsine oxide
notation: TMAO

Uranium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Uranium. A radioactive element of the actinide series of metals. URANIUM has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.
notation: U

Vitamin D
type: Class
subclass of: Diet and Nutrition
subclass of: Biomolecule
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
definition: Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body.
notation: VITD

vitamin B6
type: Class
subclass of: chemical entity
comment: This class denotes vitamin B6

Zinc
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
notation: Zn

Carbon Tetrachloride
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: CARBON TETRACHLORIDE is a solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
notation: CTET

p-Xylene*
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: P-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. Freezing point is 56°F. (USCG, 1999)
notation: PXY

alpha-linolenic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.
notation: C183N3

Styrene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: STYRENE is a colorless, toxic liquid with a strong aromatic odor. It is used to make rubbers, polymers and copolymers, and polystyrene plastics.
notation: STY

folic acid
type: Class
subclass of: chemical entity
type: NamedIndividual
type: Quality Value
comment: This class denotes folic acid
notation: HHEAR_1207

1-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 1-hydroxyphenanthrene
notation: PHEN1

zeaxanthin
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes zeaxanthin
notation: ZEA

Boron
type: Class
subclass of: Metal
definition: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.
notation: B

Arsenic
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)
notation: As

Selenium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.
notation: Se

Cobalt
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: COBALT is a trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
notation: Co

Vanadium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.
notation: V

glyphosate
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS). Source: ChEBI
notation: GPS

1, 2-Dichloroethane
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: Ethylene Dichloride is a clear, colorless, oily, synthetic, flammable liquid chlorinated hydrocarbon with a pleasant chloroform-like smell that emits toxic fumes of hydrochloric acid when heated to decomposition. Ethylene dichloride is primarily used to produce vinyl chloride. Inhalation exposure to this substance induces respiratory distress, nausea and vomiting and affects the central nervous system, liver and kidneys. It is mutagenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
notation: DE12

DDD
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: NodeShape
comment: A chlorophenylethane that is 2,2-bis(p-chlorophenyl)ethane substituted by two chloro groups at position 1. It is a metabolite of the organochlorine insecticide, DDT. (Source: ChEBI Ontology)
notation: PPDDD

2, 5-Dichlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 µg/L at 68-72°F; 33 µg/L at 86°F. Taste threshold 0.5 µg/L. (NTP, 1992)
notation: DCP25

Tungsten
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Tungsten. A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. TUNGSTEN is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.
notation: W

o-Xylene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: O-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
notation: OXY

Chromium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002, 1985), chromium and some of its compounds have been listed as known carcinogens.
notation: Cr

4-Chlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: P-chlorophenol is a white crystals with a strong phenol odor. Slightly soluble to soluble in water, depending on the isomer, and denser than water. Noncombustible. Used as an intermediate in organic synthesis of dyes and drugs.
notation: MCP4

Nickel
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: NICKEL is a trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
notation: Ni

all-cis-docosa-4, 7, 10, 13, 16, 19-hexaenoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
notation: C226N3

fluorene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho-fused tricyclic hydrocarbon that is a major component of fossil fuels and their derivatives (Source: ChEBI Ontology)
notation: FLUORENE

Nornicotine
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes Nornicotine
notation: NORN

all-cis-5, 8, 11, 14, 17-icosapentaenoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.
notation: C205N3

alpha-carotene
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes alpha-carotene
notation: ACAR

beta-hexachlorocyclohexane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes beta-hexachlorocyclohexane
notation: BHCH

m-Xylene*
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: M-xylene is a colorless watery liquid with a sweet odor. Less dense than water. Insoluble in water. Irritating vapor. (USCG, 1999)
notation: MXY

2, 4, 5-Trichlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: Exposure to 2, 4, 5-trichlorophenol may occur during its production or use as a pesticide. Acute (short-term) dermal exposure to 2, 4, 5-trichlorophenol may burn skin in humans. It also irritates the eyes, nose, pharynx, and lungs in humans. No information is available on the chronic (long-term), reproductive, developmental, or carcinogenic effects of 2, 4, 5-trichlorophenol in humans. In one study, slight degenerative changes were observed in the liver and kidneys of rats chronically exposed to 2, 4, 5-trichlorophenol in their diet. EPA has classified 2, 4, 5-trichlorophenol as a Group D, not classifiable as to human carcinogenicity. PHYSICAL DESCRIPTION: Colorless needles, gray flakes or off-white lumpy solid. Phenolic odor. Formerly used as a fungicide and bactericide.
notation: TCP245

gamma-linolenic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A C18, ω-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.
notation: C183N6

11-dehydro-thromboxane B2
type: Class
subclass of: Inflammatory Marker
type: NamedIndividual
type: NodeShape
comment: A thromboxane obtained by formal oxidation of the hemiacetal hydroxy function of thromboxane B2. (Source: ChEBI)
notation: DHTHRM

Molybdenum
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: MOLYBDENUM is a metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)
notation: Mo

Copper
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: COPPER is a heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
notation: Cu

(9Z)-hexadecenoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A hexadecenoic acid with a cis-double bond at position C-9.
notation: C161N7

2, 4, 6-Trichlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: 2 4 6-Trichlorophenol is a synthetic, colorless crystalline solid that is slightly soluble in water and soluble in organic solvents. It has been used primarily in pesticide formulations and as a wood preservative, although most uses have been cancelled in the US. When heated to decomposition, 2, 4, 6-trichlorophenol emits toxic and corrosive fumes of hydrochloric acid and other toxic gases. Exposure of humans to 2, 4, 6-trichrophenol via inhalation has been reported to cause respiratory effects, altered pulmonary function and pulmonary lesions. It is reasonably anticipated to be a human carcinogen. (NCI05)
notation: TCP246

(aminomethyl)phosphonic acid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A member of the class of phosphonic acids that is phosphonic acid substituted by an aminomethyl group. It is a metabolite of the herbicide glyphosate. Source: CHEBI
notation: AMPA

lutein
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes lutein
notation: LUT

octadecanoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics.
notation: C180

phenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: A polycyclic aromatic hydrocarbon composed of three fused benzene rings which takes its name from the two terms 'phenyl' and 'anthracene.' (Source: ChEBI Ontology)
notation: PHENANTHRENE

tetracosanoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A C24 straight-chain saturated fatty acid.
notation: C240

tetradecanoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
notation: C140

docosanoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A straight-chain, C22, long-chain saturated fatty acid.
notation: C220

Aluminum
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: ALUMINUM is a metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
notation: Al

phthalic acid
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: White crystals or fine white powder. (NTP, 1992)
notation: PA

arsenate(3−)
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes arsenate(3−)
notation: AsV

Gold
type: Class
subclass of: Metal
definition: GOLD is a yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.
notation: Au

azithromycin
type: Class
subclass of: chemical entity
type: NamedIndividual
type: NodeShape
comment: A macrolide antibiotic useful for the treatment of bacterial infections.

Monomethylarsonic Acid
type: Class
subclass of: Arsenic Species
comment: This class denotes Monomethylarsonic Acid
notation: Monomethylarsonic Acid

perylene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene comprising of five benzene rings that is anthracene in which the d,e and k,l sides are fused to benzene rings. (Source: ChEBI Ontology)
notation: PERYLENE

benzo[a]pyrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. (Source: ChEBI Ontology)
notation: BAP

arsenite(3−)
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes arsenite(3−)
notation: AsIII

Lithium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
notation: Li

Thallium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: THALLIUM is a heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
notation: Tl

Tellurium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Tellurium. An element that is a member of the chalcogen family. TELLURIUM has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.
notation: Te

Beryllium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Beryllium. An element with the atomic symbol Be, atomic number 4, and atomic weight 9.01218. Short exposure to this element can lead to a type of poisoning known as BERYLLIOSIS.
notation: Be

Silver
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
notation: Ag

Antimony
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: ANTIMONY is a metallic element that has the atomic symbol Sb, atomic number 51, and atomic weight 121.75. It is used as a metal alloy and as medicinal and poisonous salts. It is toxic and an irritant to the skin and the mucous membranes.
notation: Sb

Cesium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency.
notation: Cs

Ruthenium
type: Class
subclass of: Metal
definition: RUTHENIUM is a hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
notation: Ru

4-Hydroxybenzoic acid
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
comment: This class denotes 4-Hydroxybenzoic acid
notation: HB4

Ethyl paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
definition: Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of ethylparaben is Allergens.
notation: EtPB

Ferrous fumarate
type: Class
subclass of: HHEAR 2348
type: NamedIndividual
type: NodeShape
comment: Ferrous fumarate is an iron supplement used to treat or prevent iron deficiency anemia.

Methyl Paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
definition: Methylparaben is a Standardized Chemical Allergen. The physiologic effect of methylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of methylparaben is Allergens.
notation: MePB

Propyl paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
definition: Propylparaben is a Standardized Chemical Allergen. The physiologic effect of propylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of propylparaben is Allergens.
notation: PrPB

Barium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: BARIUM is an element of the alkaline earth group of metals. It has an atomic symbol Ba, atomic number 56, and atomic weight 138. All of its acid-soluble salts are poisonous.
notation: Ba

gamma-hexachlorocyclohexane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes gamma-hexachlorocyclohexane
notation: GHCH
notation: LIND

8-isoprostane
type: Class
subclass of: Biological Response
subclass of: Biomolecule
comment: This class denotes 8-isoprostane

acenaphthylene
type: Class
subclass of: organic polycyclic compound
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: A ortho- and peri-fused tricyclic hydrocarbon that occurs in coal tar. (Source ChEBI Ontology)
notation: ACENY

fluoranthene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring. (Source: ChEBI Ontology)
notation: FLUORANTH

Nitrogen Dioxide
type: Class
subclass of: Air Pollutant
comment: This class denotes Nitrogen Dioxide

calcium carbonate
type: Class
subclass of: chemical entity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A calcium salt with formula CCaO3.
notation: HHEAR_1206

Iodine
type: Class
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Iodine is a nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
notation: I

Ethyl mercury (C2H5Hg+)
type: Class
subclass of: Mercury Species
comment: This class denotes Ethyl mercury (C2H5Hg+)
notation: C2H5Hg

Bisphenol A
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: 4, 4'-isopropylidenediphenol is a white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)
notation: BPA

application
type: Class
subclass of: Thing
comment: This class denotes application

molecular messenger
type: Class
subclass of: Thing
comment: This class denotes molecular messenger

Bismuth
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: BISMUTH is a metallic element that has the atomic symbol Bi, atomic number 83 and atomic weight 208.98.
notation: Bi

carboxylic ester
type: Class
subclass of: Targeted Analyte
comment: This class denotes carboxylic ester

Strontium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: STRONTIUM is an element of the alkaline earth family of metals. It has the atomic symbol Sr, atomic number 38, and atomic weight 87.62.
notation: Sr

Titanium
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: TITANIUM is a dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
notation: Ti

Niobium
type: Class
subclass of: Metal
definition: Niobium. A metal element atomic number 41, atomic weight 92.906, symbol Nb. (From Dorland, 28th ed)
notation: Nb

Platinum
type: Class
subclass of: Metal
subclass of: Trace Elements
type: NamedIndividual
type: Facet Value
definition: Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) PLATINUM is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as "alutiae".
notation: Pt

Gadolinium
type: Class
subclass of: Metal
definition: Gadolinium. An element of the rare earth family of metals. GADOLINIUM has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
notation: Gd

Neptunium
type: Class
subclass of: Metal
definition: Neptunium. A radioactive element of the actinide metals family. NEPTUNIUM has the atomic symbol Np, atomic number 93, and atomic weight 237.
notation: Np

Plutonium
type: Class
subclass of: Metal
definition: Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
notation: Pu

polycyclic hydrocarbon
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes polycyclic hydrocarbon
notation: UPAH

phenols
type: Class
subclass of: Phenol
type: NamedIndividual
type: NodeShape
comment: Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. (Source: CHEBI Ontology)

1-hydroxypyrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 1-hydroxypyrene
notation: PYR1

PCB52
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB52
notation: PCB52

2,3-dinor-8-iso Prostaglandin F2 alpha
type: Class
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
comment: This class denotes 2,3-dinor-8-iso Prostaglandin F2 alpha
notation: F2A23D

Oxybenzone
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
notation: OXB

2-hydroxyfluorene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-hydroxyfluorene
notation: FLUO2

PCB118
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB118
notation: PCB118

PCB101
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB101
notation: PCB101

4-hydroxybenzophenone
type: Class
subclass of: Benzophenone
type: NamedIndividual
type: Facet Value
comment: This class denotes 4-hydroxybenzophenone
notation: OH4BP

8-iso Prostaglandin F2 alpha
type: Class
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
comment: This class denotes 8-iso Prostaglandin F2 alpha
notation: F2A8IP

benzo[b]fluoranthene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene that consists of a benzene ring fused with a acephenanthrylene ring. (Source: ChEBI Ontology)
notation: BBF

benzo[e]pyrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC. (Source: ChEBI Ontology)
notation: BEP

Benzyl paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
definition: Benzylparaben is a Standardized Chemical Allergen. The physiologic effect of benzylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of benzylparaben is Allergens.
notation: BzPB

chlorpyrifos
type: Class
subclass of: organic heterocyclic compound
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. (Source: ChEBI Ontology)
notation: CHLPYR

bis(2-ethylhexyl) adipate
type: Class
subclass of: carboxylic ester
type: NamedIndividual
type: NodeShape
comment: A diester resulting from the formal condensation of the carboxy groups of adipic acid with 2-ethylhexan-1-ol. It is used as a plasticiser in the preparation of various polymers. (Source: ChEBI Ontology)
notation: DEHA

dibutyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: NodeShape
comment: A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans. (Source: ChEBI Ontology)
notation: DBPHTH

diethyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: NodeShape
comment: The diethyl ester of benzene-1,2-dicarboxylic acid. (Source: ChEBI Ontology)
notation: DEPH

Heptyl paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
comment: This class denotes Heptyl paraben
notation: HePB

metribuzin
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3. Source: ChEBI
notation: METB

Mirex
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Mirex
notation: MIREX

N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S- (2-hydroxyethyl)-L-cysteine
notation: HEMA2

Hemoglobin
type: Class
subclass of: SIO_010043
was approved by: PER-Jim-McCusker
definition: The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae), as well as the tissues of some invertebrates. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the rest of the body (i.e. the tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power the functions of the organism in the process called metabolism.

Nitrogen Oxide
type: Class
subclass of: Metabolite
subclass of: Air Pollutant
comment: This class denotes Nitrogen Oxide

Chloroform
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
definition: CHLOROFORM is a commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
notation: CFRM

anthracene
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: An ortho-fused tricyclic hydrocarbon comprising three fused benzene rings.
notation: ANTH

Fatty Acid
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
definition: Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax.
notation: PFACID

diisononyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: NodeShape
comment: The diisononyl ester of benzene-1,2-dicarboxylic acid. (Source: ChEBI Ontology)
notation: DINP

anti-inflammatory drug
type: Class
subclass of: drug
subclass of: anti-inflammatory agent
comment: This class denotes anti-inflammatory drug

non-steroidal anti-inflammatory drug
type: Class
subclass of: anti-inflammatory drug
type: NamedIndividual
type: NodeShape
comment: An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. (Source: ChEBI Ontology)

Perfluorodecanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorodecanoic acid
notation: PFDA

Perfluorooctanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorooctanoic acid
notation: PFOA

antihypertensive agent
type: Class
subclass of: SIO_010039
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. (Source: ChEBI Ontology)
notation: HHEAR_1217

3, 4-Dihydroxy benzoic acid
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
comment: This class denotes 3, 4-Dihydroxy benzoic acid
notation: DHB34

organooxygen compound
type: Class
subclass of: Thing
comment: This class denotes organooxygen compound

Glucan
type: Class
subclass of: Allergen
comment: This class denotes Glucan

Antimalarial
type: Class
subclass of: Medication
type: NamedIndividual
type: Quality Value
definition: A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
notation: HHEAR_120

Perfluorononanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorononanoic acid
notation: PFNA

3-Chlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: White crystals with an odor of phenol. Sinks in and slowly dissolves in water. (NTP, 1992)
notation: MCP3

Cis-Chlordane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Cis-Chlordane
notation: CCHL

Trans-Chlordane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Trans-Chlordane
notation: TCHL

alpha-hexachlorocyclohexane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes alpha-hexachlorocyclohexane
notation: AHCH

pyrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system. (Source: ChEBI Ontology)
notation: PYRENE

acetamiprid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A carboxamidine that is acetamidine in which the amino hydrogens are substituted by a (6-chloropyridin-3-yl)methyl and a methyl group while the hydrogen attached to the imino nitrogen is replaced by a cyano group. Source: ChEBI
notation: ACE

nitenpyram
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group. Source: ChEBI
notation: NIT

thiacloprid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: nitrile that is cyanamide in which the hydrogens are replaced by a 1,3-thiazolidin-2-ylidene group which in turn is substituted by a (6-chloropyridin-3-yl)methyl group at the ring nitrogen. Source: ChEBI
notation: THI

clothianidin
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: An N-nitro compound consisting of 2-nitroguanidine having a (2-chloro-1,3-thiazol-5-yl)methyl group at position 1 and a methyl group at position 3. Source: ChEBI
notation: CLO

dinotefuran
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes dinotefuran
notation: DINF

thiamethoxam
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: An oxadiazane that is tetrahydro-N-nitro-4H-1,3,5-oxadiazin-4-imine bearing (2-chloro-1,3-thiazol-5-yl)methyl and methyl substituents at positions 3 and 5 respectively. Source: ChEBI
notation: THX

flonicamid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom. Source: ChEBI
notation: FLNC

3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: NodeShape
comment: This class denotes 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid

chlorfenapyr
type: Class
subclass of: azole
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: A member of the class of pyrroles that is 4-bromo-1H-pyrrole-3-carbonitrile which is substituted at positions 1, 2 and 5 by ethoxymethyl, p-chlorophenyl and trifluoromethyl groups, respectively. A proinsecticide used for termite control and crop protection against several insects and mite pests. (Source: ChEBI Ontology)
notation: CHLFEN

Perfluorooctanesulfonic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
definition: Perfluoroalkyls are stable, synthetic chemicals. Perfluoroalkyls are unique because they repel oil, grease, and water. The two perfluoroalkyls made in the largest amounts in the U. S. areperflurooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Perfluoroalkyls have been used in surface protection products such as carpet and clothing treatments and coating for paper and cardboard packaging. They have also been used in fire-fighting foams.
notation: PFOS

Perfluorobutanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorobutanoic acid
notation: PFBA

8-hydroxy-2'-deoxyguanosine
type: Class
subclass of: Biological Response
subclass of: Biomolecule
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
definition: Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.
notation: OS8OHDG

cypermethrin
type: Class
subclass of: carboxylic ester
type: NamedIndividual
type: NodeShape
comment: A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile. (Source: ChEBI Ontology)
notation: CYPERM

cyprodinil
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as well as most aquatic organisms and earthworms, but it is not considered toxic to honeybees. Source: ChEBI
notation: CYP

azoxystrobin
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture. Source: ChEBI
notation: AZO
notation: AZOXY

erythromycin A
type: Class
subclass of: chemical entity
type: NamedIndividual
type: NodeShape
comment: An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.

(15Z)-tetracosenoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: A tetracosenoic acid having a cis-double bond at position 15.
notation: C241N9

dimethyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: NodeShape
comment: CAS: 131-11-3
notation: DMPH

2-Chlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: 2-chlorophenol is a colorless to amber liquid with an unpleasant, penetrating odor. Density 1.265 g / cm3. Sinks in water and slowly dissolves. Freezing point 7°C (46°F). Boiling point 175°C (347°F).
notation: MCP2

very-low-density lipoprotein cholesterol
type: Class
subclass of: cholesterol
type: NamedIndividual
type: NodeShape
comment: Cholesterol esters and free cholesterol which are contained in or bound to very low density lipoproteins (VLDL).

low-density lipoprotein cholesterol
type: Class
subclass of: cholesterol
type: NamedIndividual
type: NodeShape
comment: Cholesterol esters and free cholesterol which are contained in or bound to low-density lipoproteins (LDL).

high-density lipoprotein cholesterol
type: Class
subclass of: cholesterol
type: NamedIndividual
type: NodeShape
comment: Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL).

indicator
type: Class
subclass of: application
type: NamedIndividual
type: NodeShape
comment: Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. (Source: ChEBI)

Triclocarban
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: Triclocarban is a triclosan analogue with an antibacterial property. Triclocarban exerts its effect by inhibiting the activity of enoyl-(acyl-carrier protein) (ACP) reductase, widely distributed in bacteria, fungi and plants. ACP reductase catalyses the last step in each cycle of fatty acid elongation in the type II fatty acid synthase systems. As a result, this agent interrupts cell membrane synthesis and leads to bacterial growth inhibition.
notation: TCC

agonist
type: Class
subclass of: Thing
comment: This class denotes agonist

Dimethylarsinic Acid
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
comment: This class denotes Dimethylarsinic Acid
notation: DMA

EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor
type: Class
subclass of: drug
type: NamedIndividual
type: NodeShape
comment: This class denotes EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor

cloxacillin
type: Class
subclass of: chemical entity
type: NamedIndividual
type: NodeShape
comment: A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6.

Methyl mercury (CH3Hg+)
type: Class
subclass of: Mercury Species
comment: This class denotes Methyl mercury (CH3Hg+)
notation: CH3Hg

cis-vaccenic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: The cis isomer of vaccenic acid.
notation: C181N7

fipronil
type: Class
subclass of: diazole
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: A racemate comprising equimolar amounts of (R)- and (S)-fipronil. (Source: ChEBI Ontology)
notation: FIPR

corticosteroid
type: Class
subclass of: chemical entity
comment: This class denotes corticosteroid

muscle relaxant
type: Class
subclass of: drug
comment: This class denotes muscle relaxant

chrysene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: NodeShape
comment: An ortho-fused polycyclic arene found commonly in the coal tar. (Source: ChEBI Ontology)
notation: CHRYSENE

organic polycyclic compound
type: Class
subclass of: Thing
comment: This class denotes organic polycyclic compound

2, 3, 5, 6-Tetrachlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: Leaflets (from ligroin) or light beige powder. (NTP, 1992)
notation: TeCP2356

Polychlorobiphenyl
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Polychlorobiphenyl
notation: SPCB

all-cis-icosa-8, 11, 14-trienoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
notation: C203N6

adrenic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
comment: This class denotes adrenic acid
notation: C224N6

(7Z, 10Z, 13Z, 16Z, 19Z)-docosapentaenoic acid
type: Class
subclass of: Fatty Acid
type: NamedIndividual
type: Facet Value
definition: The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.
notation: C225N3

malonaldehyde
type: Class
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form. (Source: ChEBI)
notation: OSMDA

Hexachlorobenzene
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Hexachlorobenzene
notation: HCB

imidacloprid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. Source: ChEBI
notation: IMI

biomarker
type: Class
subclass of: indicator
type: NamedIndividual
type: NodeShape
comment: A substance used as an indicator of a biological state. (Source: ChEBI)

Insulin
type: Class
subclass of: Metabolite
subclass of: SIO_010043
definition: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other containing 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in the treatment of type I and type II diabetes.

oxidised LDL
type: Class
subclass of: Lipid in Blood
type: NamedIndividual
type: NodeShape
comment: An oxidised form of low-density lipoprotein (LDL), regulated in vivo by a complex set of biochemical reactions and chiefly stimulated by the presence of necrotic cell debris and free radicals in the endothelium. (Source: ChEBI)
notation: OXLDL

malathion
type: Class
subclass of: carboxylic ester
type: NamedIndividual
type: NodeShape
comment: A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites. (Source: ChEBI Ontology)
notation: MALATH

folates
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: An N-acyl-L-α-amino acid anion obtained by deprotonation of any folic acid. (Source: ChEBI)
notation: FOL

anti-inflammatory agent
type: Class
subclass of: Thing
comment: This class denotes anti-inflammatory agent

cannabinoid
type: Class
subclass of: chemical entity
comment: This class denotes cannabinoid

metalaxyl
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A racemate comprising equal amounts of (R)- and (S)-metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops. Source: ChEBI
notation: MET

azole
type: Class
subclass of: Thing
comment: This class denotes azole

Cotinine
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
definition: The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
notation: COT

N,N-diethyl-m-toluamide
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide. Source: ChEBI
notation: DEET

monoethyl phthalate (DEP)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes monoethyl phthalate (DEP)
notation: MEP

Hydroxycotinine (total)
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes both Hydroxycotinine and Hydroxycotinine (total)
notation: HCOT
notation: HCOTT

3-phenoxybenzoic acid
type: Class
subclass of: Metabolite
definition: A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides.

Environmental Contaminant
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: Any minor or unwanted substance introduced into the environment that can have undesired effects. (Source: ChEBI Ontology)

pyraclostrobin
type: Class
subclass of: carboxylic ester
type: NamedIndividual
type: NodeShape
comment: A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres. (Source: ChEBI Ontology)
notation: PCLOS

flame retardant
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire. (Source: CHEBI)

2,3,4,3',4'-Pentachlorobiphenyl
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes 2,3,4,3',4'-Pentachlorobiphenyl
notation: PCB105

Trans-Nonachlor
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes Trans-Nonachlor
notation: TNON

Oxychlordane
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Oxychlordane
notation: OCHL

Adiponectin
type: Class
subclass of: Nutrient
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Adiponectin
notation: ADIPO

tebuconazole
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops. Source:ChEBI
notation: TBZ

tetraconazole
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A racemate comprising equal amounts of (R)- and (S)-tetraconazole. A fungicide used to control a range of fungal infections including powdery mildew, rusts, bunt, loose smut and scab. Source: ChEBI
notation: TETZ

Arsenobetaine
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
comment: This class denotes Arsenobetaine
notation: AsB

2-isopropyl-6-methyl-4-pyrimidinone
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A pyrimidone that is pyrimidin-4(1H)-one substituted by a methyl group at position 6 and an isopropyl group at position 2. It is a metabolite of diazinon. (Source: CHEBI)
notation: IMPY

3,5,6-trichloropyridine-2-one
type: Class
subclass of: Metabolite
definition: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.

Perfluoro-n-pentanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluoro-n-pentanoic acid
notation: PFPeA

Perfluorohexanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluorohexanoic acid
notation: PFHxA

perfluoroundecanoic acid
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: NodeShape
comment: This class denotes perfluoroundecanoic acid
notation: PFUNDA

N-methyl Perfluorooctane sulfonamido acetic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes N-methyl Perfluorooctane sulfonamido acetic acid
notation: NMFOSAA

propiconazole
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds. Source: ChEBI
notation: PRPCN

Paraben
type: Class
subclass of: Phenol
comment: This class denotes Paraben

pyrimethanil
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine. Source: ChEBI
notation: PYRM

statin
type: Class
subclass of: organooxygen compound
type: NamedIndividual
type: NodeShape
comment: Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. (Source: ChEBI Ontology)

mono-n-butylphthalate (BzBP, DnBP)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-n-butylphthalate (BzBP, DnBP)
notation: MnBP

Butyl paraben
type: Class
subclass of: Paraben
type: NamedIndividual
type: Facet Value
definition: Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
notation: BuPB

3-hydroxyfluorene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-hydroxyfluorene
notation: FLUO3

mono-methyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-methyl phthalate
notation: mMP

Cell
type: Class
subclass of: Biospecimen
subclass of: SIO_010046

native cell
type: Class
subclass of: Cell
comment: This class denotes native cell

Red Blood Cell
type: Class
subclass of: EFO_0001941
type: NamedIndividual
type: Facet
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.

Platelet
type: Class
subclass of: EFO_0001941
definition: A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.

anterior cell
type: Class
subclass of: Cell
comment: This class denotes obsolete anterior cell

neuron
type: Class
subclass of: Cell
comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. (Source: CL Ontology)

Lymphocyte
type: Class
subclass of: Leukocyte
definition: A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.

Monocyte
type: Class
subclass of: Lymphocyte
definition: Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.

experimentally modified cell in vitro
type: Class
subclass of: Cell
comment: This class denotes experimentally modified cell in vitro

Leukocyte
type: Class
subclass of: EFO_0001941
definition: An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.

cell in vitro
type: Class
subclass of: Cell
comment: A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. (Source: Cell Ontology)

abnormal cell
type: Class
subclass of: Cell
comment: This class denotes abnormal cell

neural cell
type: Class
subclass of: Cell
comment: This class denotes neural cell

compound eye retinal cell
type: Class
subclass of: Cell
comment: This class denotes compound eye retinal cell

Clinical Measurement
type: Class
subclass of: Measurement
definition: A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation.

systolic blood pressure
type: Class
subclass of: Thing
comment: This class denotes systolic blood pressure

diastolic blood pressure
type: Class
subclass of: Thing
comment: This class denotes diastolic blood pressure

body weight
type: Class
subclass of: Anthropometry
subclass of: SIO_000279
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: The resulting Force from the interaction between a person's Mass and Gravity.

body morphological measurement
type: Class
subclass of: Clinical Measurement
comment: Measurement of the structure or forms of the entire body or parts of the body of an organism. (Source: Clinical Measurement Ontology)

red blood cell count
type: Class
subclass of: SIO_000794
comment: This class denotes red blood cell count

white blood cell count
type: Class
subclass of: SIO_000794
comment: This class denotes white blood cell count

platelet count
type: Class
subclass of: SIO_000794
comment: This class denotes platelet count

blood lymphocyte count
type: Class
subclass of: SIO_000794
comment: This class denotes blood lymphocyte count

blood monocyte count
type: Class
subclass of: SIO_000794
comment: This class denotes blood monocyte count

Blood Eosinophil Count
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Blood Eosinophil Count

hematocrit
type: Class
subclass of: SIO_001018
comment: This class denotes hematocrit

mean corpuscular volume
type: Class
subclass of: SIO_000049
comment: This class denotes mean corpuscular volume

plasma indirect bilirubin level
type: Class
subclass of: Clinical Measurement
comment: This class denotes plasma indirect bilirubin level

plasma direct bilirubin level
type: Class
subclass of: Clinical Measurement
comment: This class denotes plasma direct bilirubin level

blood total cholesterol level
type: Class
subclass of: Thing
comment: Measurement of the entire amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, without taking into account any association with other molecules such as lipoproteins, in a specified volume of blood, the fluid that circulates through the heart, arteries, capillaries and veins carrying nutrients and oxygen to the body tissues and metabolites away from them. (Source: Clinical Measurements Ontology)

organ morphological measurement
type: Class
subclass of: Thing
comment: A measurement of the physical form and structure of an organ. (Source: Clinical Measurement Ontology)

body fat morphological measurement
type: Class
subclass of: Thing
comment: Measurement of adipose tissue in entire body or region of body of an organism. (Source: Clinical Measurement Ontology)

liver morphological measurement
type: Class
subclass of: organ morphological measurement
comment: Measurement of the physical form or structure of the liver, the large abdominal organ/gland which functions in the storage and filtration of blood, secretion of bile, detoxification of noxious substances, synthesis and storage of glycogen, synthesis and breakdown of fats and temporary storage of fatty acids, and synthesis of serum proteins. (Source: Clinical Measurement Ontology)

respiratory system measurement
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quality Variable
comment: This class denotes respiratory system measurement

Body Mass Index
type: Class
subclass of: Anthropometry
subclass of: Physical And Mental Assessment
subclass of: SIO_000052
subclass of: Class
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: SIO_000040
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: SIO_000279
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: A measurement relating body weight to height in an organism; typically calculated as the weight of an individual divided by the height of that individual squared. For quadrupeds, the square of body height is often replaced by the square of body length
editorial note: Should we note that this is derived from height and weight? JS: I think so

body region fat morphological measurement
type: Class
subclass of: body fat morphological measurement
comment: A measurement on the adipose tissue in a portion of the body. (Source: Clinical Measurement Ontology)

cell measurement
type: Class
subclass of: Thing
comment: This class denotes cell measurement

forced expiratory volume to forced vital capacity ratio
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes forced expiratory volume to forced vital capacity ratio
alternative label: FEV1/FVC Ratio

abdominal visceral fat area
type: Class
subclass of: abdominal fat morphological measurement
type: NamedIndividual
type: Quantity Variable
comment: Area of adipose tissue within the muscle wall surrounding the abdominal cavity. (Source: Clinical Measurement Ontology)

skin fold thickness, tricep
type: Class
subclass of: Anthropometry
comment: This class denotes skin fold thickness, tricep

skin fold thickness, subscapular
type: Class
subclass of: Anthropometry
comment: This class denotes skin fold thickness, subscapular

skin fold thickness, suprailiac
type: Class
subclass of: Anthropometry
comment: This class denotes skin fold thickness, suprailiac

forced vital capacity (FVC)
type: Class
subclass of: respiratory system measurement
type: NamedIndividual
type: Quality Variable
comment: This class denotes forced vital capacity (FVC)

forced expiratory volume
type: Class
subclass of: respiratory system measurement
type: NamedIndividual
type: Quality Variable
comment: This class denotes forced expiratory volume

mean corpuscular hemoglobin
type: Class
subclass of: Thing
comment: This class denotes mean corpuscular hemoglobin

mean corpuscular hemoglobin concentration
type: Class
subclass of: SIO_001088
comment: This class denotes mean corpuscular hemoglobin concentration

abdominal fat morphological measurement
type: Class
subclass of: body region fat morphological measurement
comment: A measurement of the physical form or structure of the adipose tissue in the body region between the thorax and pelvis. (Source: Clinical Measurement Ontology)

serum total cholesterol level
type: Class
subclass of: blood total cholesterol level
subclass of: serum cholesterol level
comment: Measurement of the entire amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, without taking into account any association with other molecules such as lipoproteins, in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. (Source: Clinical Measurements Ontology)

blood eosinophil count to total leukocyte count ratio
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes blood eosinophil count to total leukocyte count ratio

hemoglobin measurement
type: Class
subclass of: SIO_001088
comment: This class denotes hemoglobin measurement

blood vessel resistance measurement
type: Class
subclass of: Thing
comment: This class denotes blood vessel resistance measurement

blood vessel distensibility
type: Class
subclass of: Clinical Measurement
comment: This class denotes blood vessel distensibility

calculated body weight measurement
type: Class
subclass of: body weight
comment: This class denotes calculated body weight measurement

blood insulin-like growth factor 1 level
type: Class
subclass of: Biological Response
comment: This class denotes blood insulin-like growth factor 1 level

mean platelet volume
type: Class
subclass of: SIO_000049
subclass of: SIO_001109
comment: This class denotes mean platelet volume

calculated weight of islet beta cells in duodenal region of pancreas
type: Class
subclass of: Clinical Measurement
comment: This class denotes calculated weight of islet beta cells in duodenal region of pancreas

calculated weight of islet beta cells in splenic region of pancreas
type: Class
subclass of: Clinical Measurement
comment: This class denotes calculated weight of islet beta cells in splenic region of pancreas

parasite count
type: Class
subclass of: SIO_001088
comment: This class denotes parasite count

change in body weight
type: Class
subclass of: calculated body weight measurement
comment: This class denotes change in body weight

placenta morphological measurement
type: Class
subclass of: Thing
comment: This class denotes placenta morphological measurement

placenta weight
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes placenta weight

mononuclear cell measurement
type: Class
subclass of: Thing
comment: This class denotes mononuclear cell measurement

mononuclear cell count
type: Class
subclass of: SIO_000794
comment: This class denotes mononuclear cell count

food calorie intake rate
type: Class
subclass of: Thing
comment: This class denotes food calorie intake rate

body fat volume
type: Class
subclass of: body fat morphological measurement
comment: Any measurement of the size of the three dimensional space occupied by fat in the body of an organism. (Source: Clinical Measurement Ontology)

liver fat morphological measurement
type: Class
subclass of: liver morphological measurement
comment: Any measurement of the physical form or structure of the fat deposits in the liver of an organism. (Source: Clinical Measurement Ontology)

food calorie intake measurement
type: Class
subclass of: Thing
comment: This class denotes food calorie intake measurement

calorie intake measurement
type: Class
subclass of: Thing
comment: This class denotes calorie intake measurement

total calorie intake rate
type: Class
subclass of: calorie intake measurement
type: NamedIndividual
type: Quantity Variable
comment: The entire number of calories consumed by an organism per unit time, regardless of source.

serum cholesterol level
type: Class
subclass of: CMO_0002049
subclass of: CMO_0002280
comment: The amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, in a specified sample of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. Cholesterol in the serum is associated with various lipoproteins. (Source: Clinical Measurements Ontology)

calculated body weight estimate
type: Class
subclass of: Thing
comment: This class denotes calculated body weight estimate

Blood Segmented Neurophil Count
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Blood Segmented Neurophil Count

blood segmented neutrophil count to total leukocyte count ratio
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes blood segmented neutrophil count to total leukocyte count ratio

Homeostatic Model Assessment of Insulin Resistance
type: Class
subclass of: Physical And Mental Assessment
comment: This class denotes Homeostatic Model Assessment of Insulin Resistance

red blood cell morphological measurement
type: Class
subclass of: Thing
comment: This class denotes red blood cell morphological measurement

blood C-reactive protein level
type: Class
subclass of: Thing
comment: This class denotes blood C-reactive protein level

pulse wave velocity
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_001369
comment: This class denotes pulse wave velocity

total body water mass
type: Class
subclass of: calculated body weight estimate
type: NamedIndividual
type: NodeShape
comment: This measurement is a calculated/estimated value of the relative mass of total fluid in an organism. The two main fluid compartments are divided by the cell membrane into the extracellular fluid (ECF) and the intracellular fluid (ICF). (Source: CMO Ontology)

vegetative amoebae
type: Class
subclass of: SIO_010376
type: NamedIndividual
type: NodeShape
comment: This class denotes vegetative amoebae

disease of metabolism
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
type: Facet
comment: This class denotes disease of metabolism
notation: HHEAR_403

chikungunya
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes chikungunya
notation: HHEAR_1067

disease by infectious agent
type: Class
subclass of: Thing
comment: This class denotes disease by infectious agent

primary bacterial infectious disease
type: Class
subclass of: bacterial infectious disease
subclass of: Disease
comment: This class denotes primary bacterial infectious disease

ARC syndrome
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes ARC syndrome
notation: HHEAR_1019

artery disease
type: Class
subclass of: Disease
comment: This class denotes artery disease

autoimmune disease of endocrine system
type: Class
subclass of: Thing
comment: This class denotes autoimmune disease of endocrine system

developmental disorder of mental health
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development. (Source: Disease Ontology)
notation: HHEAR_341

Autism Spectrum Disorder
type: Class
subclass of: developmental disorder of mental health
type: NamedIndividual
type: Quality Value
comment: This class denotes Autism Spectrum Disorder
notation: HHEAR_151

cell type benign neoplasm
type: Class
subclass of: Thing
comment: This class denotes cell type benign neoplasm

scoliosis
type: Class
subclass of: Scoliosis or Spinal Surgery
subclass of: SIO_010056
comment: This class denotes scoliosis

Zika fever
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Zika fever
notation: HHEAR_1065

spinal disease
type: Class
subclass of: Neurological Issues with Spinal Cord
type: NamedIndividual
type: NodeShape
comment: This class denotes spinal disease

chromosomal disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes chromosomal disease

Cytomegalovirus retinitis
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Cytomegalovirus retinitis
notation: HHEAR_1102

non-alcoholic fatty liver disease
type: Class
subclass of: fatty liver disease
type: NamedIndividual
type: Quality Value
comment: A fatty liver disease characterized by the storing of excess fat in liver cells which is not caused by heavy alcohol use.
notation: HHEAR_1205

non-alcoholic fatty liver
type: Class
subclass of: non-alcoholic fatty liver disease
type: NamedIndividual
type: Quality Value
comment: This class denotes non-alcoholic fatty liver
notation: HHEAR_748

non-alcoholic steatohepatitis
type: Class
subclass of: non-alcoholic fatty liver disease
type: NamedIndividual
type: Quality Value
comment: This class denotes non-alcoholic steatohepatitis
notation: HHEAR_747

urinary tract infection
type: Class
subclass of: SIO_000475
comment: This class denotes urinary tract infection

intermittent asthma
type: Class
subclass of: Asthma Severity
type: NamedIndividual
type: Quality Value
comment: This class denotes intermittent asthma
notation: HHEAR_1113

persistent mild asthma
type: Class
subclass of: Asthma Severity
type: NamedIndividual
type: Quality Value
comment: This class denotes persistent mild asthma
notation: HHEAR_1114

persistent moderate asthma
type: Class
subclass of: Asthma Severity
type: NamedIndividual
type: Quality Value
comment: This class denotes persistent moderate asthma
notation: HHEAR_1115

childhood-onset asthma
type: Class
subclass of: Thing
comment: This class denotes childhood-onset asthma

persistent severe asthma
type: Class
subclass of: Asthma Severity
type: NamedIndividual
type: Quality Value
comment: This class denotes persistent severe asthma
notation: HHEAR_1116

human cytomegalovirus infection
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes human cytomegalovirus infection
notation: HHEAR_1103

diabetes
type: Class
subclass of: Thing
type: NamedIndividual
type: Facet
comment: This class denotes diabetes

bacterial infectious disease
type: Class
subclass of: Thing
comment: This class denotes bacterial infectious disease

pre-eclampsia
type: Class
subclass of: artery disease
type: NamedIndividual
type: Quality Value
comment: This class denotes pre-eclampsia
notation: HHEAR_177

hypertension
type: Class
subclass of: artery disease
type: NamedIndividual
type: Quality Value
comment: This class denotes hypertension
notation: HHEAR_178

microcephaly
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes microcephaly
notation: HHEAR_1020

Sickle Cell Anemia
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
definition: A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
notation: HHEAR_122

respiratory failure
type: Class
subclass of: lung disease
comment: A lung disease characterized by inadequate gas exchange by the respiratory system. (Source: Disease Ontology)

adult respiratory distress syndrome
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes adult respiratory distress syndrome
notation: HHEAR_385

gestational diabetes
type: Class
subclass of: diabetes
type: NamedIndividual
type: Quality Value
comment: This class denotes gestational diabetes
notation: HHEAR_179

bronchial disease
type: Class
subclass of: Disease
comment: This class denotes bronchial disease

granulomatosis with polyangiitis
type: Class
subclass of: Disease
comment: This class denotes granulomatosis with polyangiitis

dengue disease
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes dengue disease
notation: HHEAR_1066

Malaria
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
notation: HHEAR_121

leiomyoma
type: Class
subclass of: cell type benign neoplasm
subclass of: SIO_010056
comment: This class denotes leiomyoma

newborn respiratory distress syndrome
type: Class
subclass of: respiratory failure
type: NamedIndividual
type: Quality Value
comment: A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts. (Source: Disease Ontology)
notation: HHEAR_1176

cardiovascular system disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes cardiovascular system disease

severe pre-eclampsia
type: Class
subclass of: Eclampsia or Severe Pre-eclampsia
comment: This class denotes severe pre-eclampsia

eclampsia
type: Class
subclass of: Eclampsia or Severe Pre-eclampsia
type: NamedIndividual
type: Quality Value
comment: This class denotes eclampsia
notation: HHEAR_582

eosinophilic esophagitis
type: Class
subclass of: esophageal disease
comment: This class denotes eosinophilic esophagitis

Cerebral Malaria
type: Class
subclass of: Malaria
type: NamedIndividual
type: Quality Value
definition: A parasitic protozoa infectious disease characterized as a vector-borne infectious disease caused by the presence of protozoan parasites of the genus Plasmodium in the red blood cells, transmitted from an infected to an uninfected individual by the bite of anopheline mosquitoes, and characterized by periodic attacks of chills and fever that coincide with mass destruction of blood cells and the release of toxic substances by the parasite at the end of each reproductive cycle.
notation: HHEAR_126

respiratory system disease
type: Class
subclass of: Thing
comment: This class denotes respiratory system disease

cancer
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
comment: A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis. (Source: Disease Ontology)
notation: HHEAR_381

endocrine gland cancer
type: Class
subclass of: Thing
comment: This class denotes endocrine gland cancer

pancreatic cancer
type: Class
subclass of: endocrine gland cancer
subclass of: pancreas disease
type: NamedIndividual
type: Quality Value
comment: This class denotes pancreatic cancer
notation: HHEAR_1146

coccidiosis
type: Class
subclass of: Thing
comment: This class denotes coccidiosis

brain ischemia
type: Class
subclass of: Stroke, Cerebral Ischemia, or Cerebral infarction
subclass of: SIO_010056
comment: This class denotes brain ischemia

arteriosclerotic cardiovascular disease
type: Class
subclass of: Disease
comment: This class denotes arteriosclerotic cardiovascular disease

pancreas disease
type: Class
subclass of: Thing
comment: This class denotes pancreas disease

endocrine system disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes endocrine system disease

asthma
type: Class
subclass of: bronchial disease
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
type: Facet
comment: This class denotes asthma
notation: HHEAR_193

immune system disease
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes immune system disease
notation: HHEAR_405

bronchiolitis
type: Class
subclass of: lung disease
type: NamedIndividual
type: Quality Value
comment: This class denotes bronchiolitis
notation: HHEAR_194

food allergy
type: Class
subclass of: Thing
comment: This class denotes food allergy

chronic obstructive pulmonary disease
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes chronic obstructive pulmonary disease
notation: HHEAR_382

spinal cord disease
type: Class
subclass of: Neurological Issues with Spinal Cord
type: NamedIndividual
type: NodeShape
comment: This class denotes spinal cord disease

cerebral infarction
type: Class
subclass of: Stroke, Cerebral Ischemia, or Cerebral infarction
subclass of: SIO_010056
comment: This class denotes cerebral infarction

skin disease
type: Class
subclass of: Thing
comment: This class denotes skin disease

Disease
type: Class
subclass of: Health Outcome
subclass of: SIO_010299
comment: A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. (Source: Disease Ontology)

liver disease
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Facet
comment: This class denotes liver disease

syphilis
type: Class
subclass of: primary bacterial infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes syphilis
notation: HHEAR_1068

liver cirrhosis
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes liver cirrhosis
notation: HHEAR_756

human immunodeficiency virus infectious disease
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes human immunodeficiency virus infectious disease
notation: HHEAR_1069

pneumonia
type: Class
subclass of: lung disease
type: NamedIndividual
type: Quality Value
comment: This class denotes pneumonia
notation: HHEAR_195

esophageal disease
type: Class
subclass of: Disease
comment: This class denotes esophageal disease

juvenile rheumatoid arthritis
type: Class
subclass of: Disease
comment: This class denotes juvenile rheumatoid arthritis

hematopoietic system disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes hematopoietic system disease

gastrointestinal system disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes gastrointestinal system disease

placenta disease
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes placenta disease
notation: HHEAR_922

chronic kidney disease
type: Class
subclass of: Comorbidity Disease
comment: This class denotes chronic kidney disease

influenza
type: Class
subclass of: respiratory system disease
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes influenza
notation: HHEAR_1070

lung disease
type: Class
subclass of: Disease
comment: This class denotes lung disease

herpes simplex
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes herpes simplex
notation: HHEAR_1071

rubella
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
comment: This class denotes rubella
notation: HHEAR_1072

lupus erythematosus
type: Class
subclass of: Disease
comment: An autoimmune disease that is characterized by a constellation of findings that include elevated antibodies to nuclear antigens, antiphospholipids, low complement levels, ulcers, non-scarring alopecia, renal or neurologic damage, and low white blood cell and platelet counts, has_symptom rashes, fatigue, arthritis, hair loss, seizures, and symptoms related to affected organs.

systemic lupus erythematosus
type: Class
subclass of: lupus erythematosus
comment: A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart. (Source: Disease Ontology)

viral infectious disease
type: Class
subclass of: disease by infectious agent
subclass of: Disease
comment: This class denotes viral infectious disease

diabetes mellitus
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes diabetes mellitus
notation: HHEAR_342

type 2 diabetes mellitus
type: Class
subclass of: diabetes mellitus
type: NamedIndividual
type: Quality Value
comment: This class denotes type 2 diabetes mellitus
notation: HHEAR_181

fatty liver disease
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in liver cells via the process of steatosis. (Source: Disease Ontology)
notation: HHEAR_1180

type 1 diabetes mellitus
type: Class
subclass of: diabetes mellitus
type: NamedIndividual
type: Quality Value
comment: This class denotes type 1 diabetes mellitus
notation: HHEAR_180

toxoplasmosis
type: Class
subclass of: coccidiosis
type: NamedIndividual
type: Quality Value
comment: This class denotes toxoplasmosis
notation: HHEAR_1073

Garden
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An enclosure for displaying selected plant or animal life. (Source: Environment Ontology)
notation: HHEAR_971

building
type: Class
subclass of: Thing
type: NamedIndividual
type: NodeShape
comment: This class denotes building

Farm
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An area of land which is used for the cultivation of crops or grazing of livestock, including any agricultural constructions therein. (Source: Environment Ontology)
notation: HHEAR_970

soil
type: Class
subclass of: Environmental Material
type: NamedIndividual
type: NodeShape
comment: An environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, interstitial gases, liquids, and a broad range of resident micro- and macroorganisms. 'In engineering terms, soil is referred to as regolith, or loose rock material that lies above the 'solid geology'. Soil is commonly referred to as "earth" or "dirt"; technically, the term "dirt" should be restricted to displaced soil.' https://en.wikipedia.org/wiki/Soil " The upper limit of soil is the boundary between soil and air, shallow water, live plants, or plant materials that have not begun to decompose. Areas are not considered to have soil if the surface is permanently covered by water too deep (typically more than 2.5 meters) for the growth of rooted plants. The lower boundary that separates soil from the nonsoil underneath is most difficult to define. Soil consists of horizons near the Earth's surface that, in contrast to the underlying parent material, have been altered by the interactions of climate, relief, and living organisms over time. Commonly, soil grades at its lower boundary to hard rock or to earthy materials virtually devoid of animals, roots, or other marks of biological activity. For purposes of classification, the lower boundary of soil is arbitrarily set at 200 cm." Soil taxonomy, 2nd Ed., quoted in http://www.nrcs.usda.gov/wps/portal/nrcs/detail/soils/edu/?cid=nrcs142p2_054280 (Source: Environment Ontology)

air
type: Class
subclass of: Environmental Material
subclass of: Thing
type: NamedIndividual
type: Facet
comment: This class denotes air

Dust
type: Class
subclass of: Environmental Material
comment: Particulate environmental material with diameters less than 500 micrometers. (Source: Environment Ontology)

Shop
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A building in which a business presents a selection of goods and offers to trade or sell them to customers for money or other goods. (Source: Environment Ontology)
notation: HHEAR_981

Drinking Water
type: Class
subclass of: Environmental Material
type: NamedIndividual
type: Facet
definition: Drinking Water
definition: Drinking water is water which may be consumed by humans with no adverse effects on their health.

Environmental Material
type: Class
subclass of: SIO_010412
comment: This class denotes Environmental Material

respirable suspended particulate matter
type: Class
subclass of: Air Pollutant
comment: A portion of respirable suspended particulate matter is a form of particulate matter composed primarily of solid particles each with a diameter of 10 micrometers or less. [database_cross_reference: https://en.wikipedia.org/wiki/Particulates]

fine respirable suspended particulate matter
type: Class
subclass of: respirable suspended particulate matter
type: NamedIndividual
type: Quality Variable
comment: A portion of fine respirable suspended particulate matter is a form of particulate matter composed primarily of solid particles each with a diameter of 2.5 micrometers or less. [database_cross_reference: https://en.wikipedia.org/wiki/Particulates]

domestic garden
type: Class
subclass of: SIO_000955
type: NamedIndividual
type: NodeShape
comment: A garden that is associated with a human house. This association is generally one of spatial proximity or parthood.

building part
type: Class
subclass of: building
type: NamedIndividual
type: NodeShape
comment: This class denotes building part

indoor kitchen
type: Class
subclass of: building part
subclass of: Kitchen
type: NamedIndividual
type: NodeShape
comment: This class denotes indoor kitchen

Living Room
type: Class
subclass of: room
subclass of: Room
subclass of: Living Room or Child's Bedroom
subclass of: Living Room or Child's Bedroom or Kitchen
type: NamedIndividual
type: NodeShape
comment: This class denotes Living Room

room
type: Class
subclass of: building part
comment: This class denotes room

Factory
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A factory (previously manufactory) or manufacturing plant is an industrial site, usually consisting of buildings and machinery, or more commonly a complex having several buildings, where workers manufacture goods or operate machines processing one product into another. (Source: Environment Ontology)
notation: HHEAR_969

Motor Vehicle
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A motor vehicle is a vehicle which is propelled by an engine or motor and that does not operate on rails. (Source: Environment Ontology)
notation: HHEAR_978

Car
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: Quality Value
comment: This class denotes Car
notation: HHEAR_248

Human Dwelling
type: Class
subclass of: Housing Characteristic
type: NamedIndividual
type: Quality Variable
comment: A self-contained constructed feature used by one or more households as a home, such as a house, apartment, mobile home, houseboat or other 'substantial' structure. A dwelling typically includes nearby outbuildings, sheds etc. within the curtilage of the property, excluding any 'open fields beyond'. It has significance in relation to search and seizure, conveyancing of real property, burglary, trespass, and land use planning. (Source: Environment Ontology)

Residential Building
type: Class
subclass of: Human Dwelling
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: Quality Variable
comment: This class denotes Residential Building
notation: HHEAR_154

Restaurant
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A building within which food and drink are prepared and served to customers in exchange for money or other goods and/or services. (Source: Environment Ontology)
notation: HHEAR_980

Market
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A part of an ecosystem where people gather for the purchase and sale of provisions, livestock, and other goods. As with campgrounds and fairgrounds, land use is the key differentia here. The regularity of marketplace activities may provide a differentia for further growth of this branch. (Source: Environment Ontology)
notation: HHEAR_977

Office
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A building part within which administrative work is done by an organisations users in order to support and realise the objectives of that organization. (Source: Environment Ontology)
notation: HHEAR_979

Laboratory Facility
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A research facility in which systems of manufactured products control internal conditions and in which scientific or technological research, experiments, and measurement may be performed. (Source: Environment Ontology)
notation: HHEAR_975

Warehouse
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An industrial building which is used to store goods. (Source: Environment Ontology)
notation: HHEAR_982

Water Tank
type: Class
subclass of: Q10713454
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A container for storing water. (Source: wikidata.org)
notation: HHEAR_992

Barn
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An agricultural building used for crop storage or animal husbandry. (Source: Environment Ontology)
notation: HHEAR_966

Hotel
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A building which 1) containing multiple dwellings of pre-furnished accommodation and 2) is rented on a short term and/or longer-term basis. (Source: Environment Ontology)
notation: HHEAR_974

ingestion
type: Class
subclass of: SIO_000475
comment: This class denotes ingestion

Occupation
type: Class
subclass of: Socioeconomic Status
subclass of: SIO_000016
type: NamedIndividual
type: Quality Variable
type: Facet
was approved by: PER-Jeanette-Stingone
definition: An individual attribute that is the usual or principal work or business of an individual.

health status
type: Class
subclass of: Thing
comment: This class denotes health status

Education
type: Class
subclass of: Socioeconomic Status
subclass of: SIO_000026
type: NamedIndividual
type: Quality Variable
type: Facet
was approved by: PER-Jeanette-Stingone
definition: The act or process of imparting or acquiring knowledge.

built environment
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: Facet
type: NodeShape
comment: Human-made surroundings that provide the setting for human activity, ranging in scale from personal shelter and buildings to neighborhoods and cite, and can often include their supporting infrastructure, such as water supply or energy networks. (Source: ExO Ontology)

Diet
type: Class
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Variable
definition: The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.

Smoking Status
type: Class
subclass of: smoking behavior trait
type: NamedIndividual
type: Quality Value
type: Quality Variable
definition: An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history
editorial note: We need to discuss this entire hierarchy.
notation: HHEAR_197

Waist
type: Class
subclass of: SIO_010046
definition: The waist is the part of the abdomen between the rib cage and hips. On people with slim bodies, the waist is the narrowest part of the torso.

food product
type: Class
subclass of: SIO_010363
type: NamedIndividual
type: NodeShape
comment: This class denotes food product

food transformation process
type: Class
subclass of: SIO_000006
type: NamedIndividual
type: NodeShape
comment: A process involving the physical transformation of a food source or food product into some derived organic material or food product

beverage
type: Class
subclass of: beverage food product
type: NamedIndividual
type: NodeShape
comment: A liquid prepared for consumption

beverage food product
type: Class
subclass of: food product
type: NamedIndividual
type: NodeShape
comment: A liquid prepared for consumption, or a product that can be combined with water or milk to make one.

fish
type: Class
subclass of: Eukaryota
comment: A gill-bearing aquatic craniate animal that lacks limbs with digits. (Source: Food Ontology)

food product organismal source
type: Class
subclass of: SIO_010046
comment: This class denotes food product organismal source

food reheating
type: Class
subclass of: food transformation process
type: NamedIndividual
type: NodeShape
comment: A process to bring an already fully cooked product to serving temperature.

food packaging
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: Facet
type: NodeShape
comment: A food contact material which encloses the food and can be in the type of a container, packaging or wrapping. (Source: Food Ontology)

metal container
type: Class
subclass of: container
type: NamedIndividual
type: NodeShape
comment: This class denotes metal container

plastic container
type: Class
subclass of: container
type: NamedIndividual
type: NodeShape
comment: Corresponds to FSTA Thesaurus Packaging 2.2.1 Plastic container.

genomic feature
type: Class
subclass of: Thing
type: NamedIndividual
type: NodeShape
comment: A sequence feature (continuous extent of biological sequence) that is of genomic origin (i.e. carries sequence from the genome of a cell or organism)

polymorphic allele
type: Class
subclass of: allele
type: NamedIndividual
type: NodeShape
comment: An allele that is fixed in a population at some stable level, typically > 1%. Polymorphic alleles reside at loci where more than one version exists at some significant frequency in a population. (source: PMID: 25741868 ACMG Guidelines)

major polymorphic allele
type: Class
subclass of: polymorphic allele
type: NamedIndividual
type: NodeShape
comment: A polymorphic allele that is present at the highest frequency relative to other polymorphic variants at the same genomic location.

minor polymorphic allele
type: Class
subclass of: polymorphic allele
type: NamedIndividual
type: NodeShape
comment: A polymorphic allele that is not present at the highest frequency among all fixed variants at the locus (i.e. not the major polymorphic allele at a given location).

allele
type: Class
subclass of: genomic feature
subclass of: SIO_010277
type: NamedIndividual
type: NodeShape
comment: One of a set of sequence features known to exist at a particular genomic location.

defense response
type: Class
subclass of: Thing
comment: This class denotes defense response

inflammatory response
type: Class
subclass of: defense response
subclass of: Biological Response
comment: This class denotes inflammatory response

immune response
type: Class
subclass of: Biological Response
subclass of: SIO_000475
type: NamedIndividual
type: Quality Variable
comment: This class denotes immune response

behavior
type: Class
subclass of: Thing
comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).

biological_process
type: Class
subclass of: Thing
comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.

CD4-positive, alpha-beta T cell activation
type: Class
subclass of: alpha-beta T cell activation
subclass of: Biological Response
comment: This class denotes CD4-positive, alpha-beta T cell activation

T-helper 1 cell activation
type: Class
subclass of: CD4-positive, alpha-beta T cell activation
comment: This class denotes T-helper 1 cell activation

T-helper 2 cell activation
type: Class
subclass of: CD4-positive, alpha-beta T cell activation
comment: This class denotes T-helper 2 cell activation

alpha-beta T cell activation
type: Class
subclass of: Thing
comment: This class denotes alpha-beta T cell activation

behavioral response to pain
type: Class
subclass of: SIO_000475
comment: This class denotes behavioral response to pain

Phenotype
type: Class
subclass of: Health Outcome
comment: This class denotes Phenotype

Phenotypic abnormality
type: Class
subclass of: SIO_000475
comment: This class denotes Phenotypic abnormality

Retinopathy
type: Class
subclass of: Phenotype
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
definition: Any noninflammatory disease of the retina. This nonspecific term is retained here because of its wide use in the literature, but if possible new annotations should indicate the precise type of retinal abnormality.
notation: HHEAR_129

Autism
type: Class
subclass of: Phenotypic abnormality
type: NamedIndividual
type: Facet
type: NodeShape
comment: Autism is a neurodevelopmental disorder characterized by impaired social interaction and communication, and by restricted and repetitive behavior. Autism begins in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual (DSM-IV).

Lack of spontaneous play
type: Class
subclass of: SIO_000475
comment: This class denotes Lack of spontaneous play

Eczema
type: Class
subclass of: Inflammatory abnormality of the skin
type: NamedIndividual
type: Quality Value
comment: Eczema has several forms including atopic dermatitis, contact dermatitis, dyshidrotic eczema, nummular eczema, seborrheic dermatitis, and stasis dermatitis. Eczema is a form of dermatitis. The term eczema is broadly applied to a range of persistent skin conditions and can be related to a number of underlying conditions. Manifestations of eczema can include dryness and recurring skin rashes with redness, skin edema, itching and dryness, crusting, flaking, blistering, cracking, oozing, or bleeding.
notation: HHEAR_425

Skin rash
type: Class
subclass of: Inflammatory abnormality of the skin
type: NamedIndividual
type: Quality Value
comment: A red eruption of the skin.
notation: HHEAR_426

Intellectual disability
type: Class
subclass of: Neurodevelopmental abnormality
subclass of: Developmental delay or intellectual disability
type: NamedIndividual
type: NodeShape
comment: Subnormal intellectual functioning which originates during the developmental period. Intellectual disability, previously referred to as mental retardation, has been defined as an IQ score below 70. This term should be used for children at least five years old. For younger children, consider the term Global developmental delay (HP:0001263).

Seizures
type: Class
subclass of: Phenotype
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
definition: Seizures are an intermittent abnormality of the central nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons and characterized clinically by some combination of disturbance of sensation, loss of consciousness, impairment of psychic function, or convulsive movements. The term epilepsy is used to describe chronic, recurrent seizures.
notation: HHEAR_125

Hypotonia
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Hypotonia is an abnormally low muscle tone (the amount of tension or resistance to movement in a muscle). Even when relaxed, muscles have a continuous and passive partial contraction which provides some resistance to passive stretching. Hypotonia thus manifests as diminished resistance to passive stretching. Hypotonia is not the same as muscle weakness, although the two conditions can co-exist. Hypotonia can be caused by abnormalities of the central nervous system, any element of the motor unit (including the lower motoneuron), or both. Hypotonia is not a specific diagnosis, but can be observed in hundreds of genetic and other diseases. The first distinction to make when assessing a child with hypotonia is whether decreased muscle tone is a result of an abnormality of the central nervous system (CNS), peripheral neuromuscular system, or a combined abnormality involving both. Clinical findings suggestive of an abnormality of the CNS may include hyperreflexia, cognitive developmental delay, and seizures. In contrast, physical findings pointing towards a neuromuscular origin may include weakness, lack of antigravity movements, muscle atrophy, fasciculations, and/or diminished reflexes, most often in the context of normal cognitive function. The HPO term does not distinguish between these etiologies. Additional HPO terms should be used as required to describe associated features. (Source: Human Phenotype Ontology)
notation: HHEAR_1018

Coma
type: Class
subclass of: Phenotype
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
definition: Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli.
notation: HHEAR_124

Hepatic fibrosis
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: NodeShape
comment: The presence of excessive fibrous connective tissue in the liver. Fibrosis is a reparative or reactive process. (Source: Human Phenotype Ontology)

Hepatic failure
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Hepatic failure
notation: HHEAR_395

Periportal fibrosis
type: Class
subclass of: Hepatic fibrosis
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Liver fibrosis is not only the result of necrosis, collapse and scar formation but also the result of derangements in the synthesis and degradation of matrix by injured mesenchymal cells. The presence of fibrosis affecting the interlobular stroma of liver. (Source: Human Phenotype Ontology)
notation: HHEAR_754

Intrauterine growth retardation
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Intrauterine growth restriction is a newer term that is preferred over Intrauterine growth retardation. The causes of IUGR include maternal abnormalities (chronic hypertension, cyanotic heart disease, smoking, drug abuse), placental or umbilical cord abnormalities (including placenta previa and cord anomalies), maternal medicationas, and genetic disorders of the fetus. An abnormal restriction of fetal growth with fetal weight below the tenth percentile for gestational age. (Source: Human Phenotype Ontology)
notation: HHEAR_921

Obesity
type: Class
subclass of: DOID 9970
subclass of: Body Weight Quality
type: NamedIndividual
type: Quality Value
comment: Accumulation of substantial excess body fat.
notation: HHEAR_63

Nasal congestion
type: Class
subclass of: Sneezing, Runny Nose, or Congestion
type: NamedIndividual
type: NodeShape
comment: Reduced ability to pass air through the nasal cavity often leading to mouth breathing.

Anemia
type: Class
subclass of: Phenotype
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
definition: A reduction in erythrocytes volume or hemoglobin concentration.
notation: HHEAR_128

Fever
type: Class
subclass of: Phenotype
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
definition: Elevated body temperature due to failed thermoregulation.
notation: HHEAR_123

Abnormality of the respiratory system
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Quality Variable
comment: This class denotes Abnormality of the respiratory system

Respiratory distress
type: Class
subclass of: SIO_000475
comment: This class denotes Respiratory distress

Abnormality of the spinal cord
type: Class
subclass of: Neurological Issues with Spinal Cord
type: NamedIndividual
type: NodeShape
comment: An abnormality of the spinal cord (myelon).

Sleep disturbance
type: Class
subclass of: SIO_000475
comment: This class denotes Sleep disturbance

Allergic rhinitis
type: Class
subclass of: Allergy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: It is characterized by one or more symptoms including sneezing, itching, nasal congestion, and rhinorrhea.
notation: HHEAR_596

Increased Body Weight
type: Class
subclass of: Body Weight Quality
subclass of: Restriction
  on property: SIO_000011
  some values from: Restriction
    on property: SIO_000008
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: NamedIndividual
type: Quality Value
definition: BMI > 25
notation: HHEAR_72

Inflammatory abnormality of the skin
type: Class
subclass of: skin disease
subclass of: Health Outcome
type: NamedIndividual
type: NodeShape
comment: The presence of inflammation of the skin. That is, an abnormality of the skin resulting from the local accumulation of fluid, plasma proteins, and leukocytes.

Allergy
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Allergy
notation: HHEAR_279

Abnormal nervous system physiology
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Abnormal nervous system physiology
notation: HHEAR_352

Cough
type: Class
subclass of: wheezing or tightness in the chest or cough
comment: This class denotes Cough

Neurodevelopmental delay
type: Class
subclass of: Neurodevelopmental abnormality
subclass of: Developmental delay or intellectual disability
type: NamedIndividual
type: NodeShape
comment: This class denotes Neurodevelopmental delay

Neurodevelopmental abnormality
type: Class
subclass of: Abnormal nervous system physiology
type: NamedIndividual
type: NodeShape
comment: A deviation from normal of the neurological development of a child, which may include any or all of the aspects of the development of personal, social, gross or fine motor, and cognitive abilities. This term should be used to describe abnormalities with onset in the developmental period.

Hepatic bridging fibrosis
type: Class
subclass of: Hepatic fibrosis
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Hepatic fibrosis that reaches from a portal area to another portal area. (Source: Human Phenotype Ontology)
notation: HHEAR_755

Sneeze
type: Class
subclass of: Sneezing, Runny Nose, or Congestion
type: NamedIndividual
type: NodeShape
comment: A sudden violent, spasmodic, audible expiration of breath through the nose and mouth.

Overweight
type: Class
subclass of: Body Weight Quality
subclass of: Restriction
  on property: SIO_000011
  some values from: Restriction
    on property: SIO_000008
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: NamedIndividual
type: Quality Value
comment: This class denotes Overweight
notation: HHEAR_71

Wheezing
type: Class
subclass of: wheezing or tightness in the chest or cough
type: NamedIndividual
type: Quality Value
comment: This class denotes Wheezing
notation: HHEAR_597

Chest tightness
type: Class
subclass of: wheezing or tightness in the chest or cough
comment: This class denotes Chest tightness

Rhinorrhea
type: Class
subclass of: Sneezing, Runny Nose, or Congestion
type: NamedIndividual
type: NodeShape
comment: Increased discharge of mucus from the nose.

Family history
type: Class
subclass of: Medical History
type: NamedIndividual
type: Quality Variable
comment: This class denotes Family history

Abnormality of the musculoskeletal system
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Abnormality of the musculoskeletal system
notation: HHEAR_386

Hepatic Lobular Inflammation
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: NodeShape
comment: Each liver lobule is hexagonal in cross section and is centered on the central vein (teh central veins are branches of the hepatic vein). Within lobules, hepatocytes are arranged into hepatic cords separated by adjacent sinusoids. Infiltration of inflammatory cells in lobules of the liver. A focus of lobular inflammation can be defined as two or more inflammatory cells (neutrophils, lymphocytes and other mononuclear cells, eosinophils and microgranulomas) within the lobule present within the sinusoids or surrounding injured hepatocytes (ballooned or apoptotic hepatocytes). (Source: Human Phenotype Ontology)

Underweight
type: Class
subclass of: Body Weight Quality
subclass of: Underweight/Normal
subclass of: Restriction
  on property: SIO_000011
  some values from: Restriction
    on property: SIO_000008
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: NamedIndividual
type: Quality Value
definition: BMI < 18.5
notation: HHEAR_99

Sepsis
type: Class
subclass of: Sepsis, Septic Shock, or SIRS
subclass of: SIO_010056
comment: This class denotes Sepsis

data item
type: Class
subclass of: SIO_000052
comment: This class denotes data item

measurement datum
type: Class
subclass of: data item
comment: This class denotes measurement datum

infection
type: Class
subclass of: SIO_000475
subclass of: SIO_010056
type: NamedIndividual
type: Quality Variable
comment: This class denotes infection

hospital-acquired infection
type: Class
subclass of: infection
comment: This class denotes hospital-acquired infection

surgical procedure
type: Class
subclass of: SIO_001024
type: NamedIndividual
type: Quality Variable
comment: This class denotes surgical procedure

Pharmacotherapy
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Medical Therapy Procedure
type: NamedIndividual
type: Quality Variable
comment: This class denotes Pharmacotherapy

proton pump inhibitor agent therapy
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: NodeShape
comment: This class denotes proton pump inhibitor agent therapy

artificial respiration
type: Class
subclass of: SIO_001398
comment: This class denotes artificial respiration

tracheostomy
type: Class
subclass of: SIO_001024
comment: This class denotes tracheostomy

extracorporeal membrane oxygenation
type: Class
subclass of: ventilator supporting therapy
subclass of: SIO_001024
comment: This class denotes extracorporeal membrane oxygenation

vasopressor agent therapy
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: Quality Variable
comment: This class denotes vasopressor agent therapy

renal dialysis
type: Class
subclass of: ventilator supporting therapy
subclass of: Home Medical Technology
subclass of: SIO_001024
comment: This class denotes renal dialysis

central venous cannula insertion
type: Class
subclass of: Medical History
subclass of: Activity
comment: This class denotes central venous cannula insertion

noninvasive positve-pressure ventilation
type: Class
subclass of: artificial respiration
subclass of: Medical History
comment: This class denotes noninvasive positve-pressure ventilation

blood transfusion
type: Class
subclass of: SIO_001024
type: NamedIndividual
type: Quality Value
comment: This class denotes blood transfusion
notation: HHEAR_380

nutrition intake
type: Class
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Variable
type: Activity
definition: Nutrition intake is the process of taking in of nutrients, especially by eating or drinking, considered in relation to the body’s dietary needs.

executive function assessment
type: Class
subclass of: Neurocognitive Assessment
type: NamedIndividual
type: NodeShape
comment: Evaluation of organizing and planning ability, as well as working memory, mental flexibility, list-making, and execution of tasks. (Source: MAXO Ontology)

psychiatric disorder
type: Class
subclass of: Comorbidity Disease
comment: This class denotes psychiatric disorder

spinal injury
type: Class
subclass of: Neurological Issues with Spinal Cord
type: NamedIndividual
type: NodeShape
comment: This class denotes spinal injury

behavioral phenotype
type: Class
subclass of: SIO_010056
comment: This class denotes behavioral phenotype

Consumption Behavior
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: NamedIndividual
type: Quality Variable
comment: This class denotes Consumption Behavior

Consumption of an Addictive Substance
type: Class
subclass of: Consumption Behavior
type: NamedIndividual
type: NodeShape
comment: Behavior related to the intake of addictive substances. (Source: Neuro Behavior Ontology)

Cannabis Consumption
type: Class
subclass of: Consumption Behavior
type: NamedIndividual
type: NodeShape
comment: This class denotes cannabis consumption

Partner
type: Class
subclass of: SIO_000016
type: NamedIndividual
type: NodeShape
comment: A person that is associated with another person in some manner or action. (Source: NCI Thesaurus)

Immature Granulocytes to Leukocytes Ratio Measurement
type: Class
subclass of: Immature Granulocytes Measurement
type: NamedIndividual
type: NodeShape
comment: The determination of the ratio of immature granulocytes compared to total leukocytes present in a sample. The measurement may be expressed as a ratio or percentage. (Source: NCI Thesaurus)

Transient Tachypnea of the Newborn
type: Class
subclass of: Neonatal Disorder
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A respiratory disorder characterized by higher than normal respiratory rates among premature and cesarean section delivered neonates whose lungs have not fully matured. The cause is often excess fluid in the lungs, and resolution is aided by supplemental oxygen and sometimes, antibiotics. (Source: NCI Thesaurus)
notation: HHEAR_1177

Pulsatility Index
type: Class
subclass of: blood vessel resistance measurement
type: NamedIndividual
type: NodeShape
comment: A diagnostic indicator of vascular resistance that is calculated by dividing the difference between the peak systolic and minimum diastolic blood velocities by the mean velocity.

Strongly Agree
type: Class
subclass of: Agree
type: NamedIndividual
type: NodeShape
comment: Intense concurrence. [Definition Source: NCI]

Strongly Disagree
type: Class
subclass of: Disagree
type: NamedIndividual
type: NodeShape
comment: Intensely at odds. [Definition Source: NCI]

Agree
type: Class
subclass of: Agreement Answer
type: NamedIndividual
type: NodeShape
comment: To concur. [Definition Source: NCI]

Disagree
type: Class
subclass of: Agreement Answer
type: NamedIndividual
type: NodeShape
comment: To be at odds. [Definition Source: NCI]

Menopause Status
type: Class
subclass of: Life Stage
type: NamedIndividual
type: NodeShape
comment: An indicator as to whether the female subject is in menopause. (Source: NCI Thesaurus)

Cuban
type: Class
subclass of: Hispanic or Latino Ethnicity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person of Cuban culture or origin, regardless of race. (Source: NCI Thesaurus)
notation: HHEAR_671

Other Hispanic or Latino(a)
type: Class
subclass of: Hispanic or Latino Ethnicity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person of Spanish culture or origin, but not Cuban, Mexican, Puerto Rican, South or Central American, regardless of race. (Source: NCI Thesaurus)
notation: HHEAR_674

Pre-gestational Diabetes
type: Class
subclass of: diabetes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Diabetes diagnosed before current pregnancy. (Source: reVITALize)
notation: HHEAR_693

Chronic Maternal Hypertension
type: Class
subclass of: hypertension
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Hypertension that predates pregnancy. (Source: NCI Thesaurus)
notation: HHEAR_585

Reactive Airway Disease
type: Class
subclass of: Non-Neoplastic Lung Disorder
type: NamedIndividual
type: Quality Value
definition: Coughing, wheezing, or shortness of breath that is triggered by allergens, infection, or other irritants. [def-source: NCI]
notation: HHEAR_186

Live Birth
type: Class
subclass of: Pregnancy Outcome By Fetal Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The complete expulsion or extraction from the mother of a fetus, irrespective of the duration of pregnancy, which, after such expulsion or extraction, breathes or shows any other evidence of life, such as beating of the heart, pulsation of the umbilical cord, or definite movement of voluntary muscles. (Source: NCI Thesaurus)
notation: HHEAR_1074

Spontaneous Labor and Birth
type: Class
subclass of: Birth Outcome
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Initiation of labor without the use of pharmacological and/or mechanical interventions, resulting in a non-operative vaginal birth. (reVITALize) [Definition Source: NCI][attribution: NICHD]
notation: HHEAR_609

Breast Fibroglandular Tissue
type: Class
subclass of: Mammary Gland Tissue
type: NamedIndividual
type: NodeShape
comment: Breast tissue that contains glandular epithelial and fibrous tissue. (Source: NCI Thesaurus)

Kaufman Assessment Battery for Children
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: A clinical tool used to assess a child's strengths and weaknesses in cognitive ability and mental processing. (Source: NCI Thesaurus)

Larger Axis of Placenta
type: Class
subclass of: placenta morphological measurement
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length, in cm, of the longest axis of the chorionic disc.
alternative label: Placental Length

Shorter Axis of Placenta
type: Class
subclass of: placenta morphological measurement
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Shorter Axis of Placenta

Systemic Vascular Resistance
type: Class
subclass of: blood vessel resistance measurement
type: NamedIndividual
type: NodeShape
comment: The resistance to blood flow offered by all systemic vasculature, excluding pulmonary vasculature. The major determinant of SVR is arteriolar tone, but blood viscosity and vascular capacitance are also contributing factors.
alternative label: Total Peripheral Resistance

Significant Other
type: Class
subclass of: Marital Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A gender-neutral term for a person's partner in an intimate or romantic relationship without disclosing or presuming marital status or sexual orientation. [Definition Source: NCI]
notation: HHEAR_451

Alternaria
type: Class
subclass of: Fungus
comment: A genus of dematiaceous fungi within the phylum Ascomycota that are ubiquitous in nature and are common allergens in humans. Members of the Alternaria genus produce septate, brown and filamentous hyphae, and may cause opportunistic infections in immunocompromised individuals, such as phaeohyphomycosis, onychomycosis, sinusitis, ulcerated cutaneous infections, keratitis, visceral infections and osteomyelitis. (Source: NCI Thesaurus)

Forced Expiratory Flow at 25-75 Percent
type: Class
subclass of: respiratory system measurement
type: NamedIndividual
type: Quality Variable
comment: This class denotes Forced Expiratory Flow at 25-75 Percent

Clinical Observations Severity
type: Class
subclass of: Thing
comment: The degree of something undesirable as determined by clinical observations. (Source: NCI Thesaurus)

Scaled Score
type: Class
subclass of: score
type: NamedIndividual
type: NodeShape
comment: Conversion of a raw score on a test to a common scale that allows for a numerical comparison. (Source: NCI Thesaurus)

T-Score
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
definition: A method for converting an individual score into a standard form. While similar to a z-score, t-score is used when the conversion is made without knowledge of the population standard deviation and mean.

Total Score
type: Class
subclass of: score
type: NamedIndividual
type: NodeShape
comment: The sum of a set of numeric values. (Source: NCI Thesaurus)

Spanish Language
type: Class
subclass of: Acculturation
type: NamedIndividual
type: Quality Value
definition: The Spanish Language
notation: HHEAR_244

Composite Score
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quality Variable
definition: A single value that is calculated from multiple scores. This composite score can then be used as a single variable in further analysis and comparison. [def-source: NCI]

Anxiety Scale
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A rating scale included in the Behavior Assessment System for Children that measures the tendency of the subject to be nervous, fearful, or worried about real or imagined problems. (Source: NCI Thesaurus)

Behavior Rating Inventory of Executive Function
type: Class
equivalent class: CAO_01011
subclass of: Questionnaire
subclass of: executive function assessment
type: NamedIndividual
type: NodeShape
comment: A standardized rating scale designed to assess the executive function behaviors in the school and home environments for children and adolescents as observed by a parent or teacher. (Source: NCI Thesaurus)

Central Line Infection
type: Class
subclass of: hospital-acquired infection
subclass of: CAUTI or CLABSI or VAP
subclass of: Restriction
  on property: SIO_001157
  some values from: central venous cannula insertion
comment: This class denotes Central Line Infection

Subungual Exostosis
type: Class
subclass of: Disease
type: NamedIndividual
type: NodeShape
comment: A benign lesion that affects the distal phalanx, most often the great toe. Grossly it consists of a cartilage cap and a bony stalk. Microscopically it is characterized by an osteochondromatous proliferation with a gradual transition of a peripheral spindle-cell proliferation to hyaline cartilage to trabecular bone. Pain and swelling are present. Simple resection is usually curative. [Definition Source: NCI]

HLA Complex
type: Class
subclass of: Protein Family
subclass of: Medical History
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A family of proteins that are essential for the presentation of peptide antigens on cell surfaces that modulate the host defensive activities of T-cells. This protein family includes major histocompatibility complex (MHC) class I and class II proteins. [Definition Source: NCI]

Asthma Quality of Life Questionnaire
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: A standardized rating scale developed by Juniper et al in 1992, which is used to measure the physical and emotional impacts on quality of life in patients with asthma. This questionnaire contains 32 items using a 7-point scale, and the items are grouped into four domains: activity limitations, symptoms, emotional function, and exposure to environmental stimuli. (Source: NCI Thesaurus)

Number of Years of Education
type: Class
subclass of: Demographic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The number of education years that a subject has competed. (Source: NCI Thesaurus)

Chest Tube
type: Class
subclass of: Medical Device
type: NamedIndividual
type: NodeShape
comment: A hollow tube that is inserted into the pleural space through a surgical incision in the chest wall. [Definition Source: NCI]

Asthma Control Test Questionnaire
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: A standardized rating scale developed by Nathan et al in 2004, which is used to identify patients with poorly controlled asthma. This questionnaire contains 5 items. (Source: NCI Thesaurus)

Mammary Gland Tissue
type: Class
subclass of: SIO_010002
subclass of: Restriction
  on property: SIO_000068
  some values from: UBERON_0000310
type: NamedIndividual
type: NodeShape
comment: The glandular tissue of the breast. In females, it is composed of numerous lobules with alveolar ducts and alveoli. In males, it is composed of rudimentary glands. (Source: NCI Thesaurus)

Respiratory System Findings Original Result
type: Class
subclass of: Thing
comment: This class denotes Respiratory System Findings Original Result

Flow-Mediated Vasodilation
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: The percent change in arterial vessel diameter in response to an increase in blood flow caused by mechanical or chemical stimuli, which is usually measured using ultrasound-based methods. This measurement can reflect the functionality of the endothelium in the observed blood vessels. (Source: NCI Thesaurus)

Pathology Result
type: Class
subclass of: Laboratory Test Result
type: NamedIndividual
type: NodeShape
comment: The outcome of a pathologic examination. (Source: NCI Thesaurus)

Behavior Assessment System for Children, Third Edition
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A comprehensive set of rating scales designed to facilitate the differential diagnosis and classification of a variety of emotional and behavioral disorders of children, aid in the design of treatment plans, and provide insight into an individual's thoughts and feelings. Version three incorporates additional questionnaires, scales and forms. (Source: NCI Thesaurus)

Edinburgh Postnatal Depression Scale
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A 10-item, self-rating questionnaire designed to screen postpartum women for indications of depression. (Source: NCI Thesaurus)

Stepmother
type: Class
subclass of: Step Parent
subclass of: Mother
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female who is married to a spouse with children whom are not biologically related to her. (Source: NCI Thesaurus)
notation: HHEAR_656

Seventh
type: Class
subclass of: Ordinal Position
type: NamedIndividual
type: NodeShape
comment: Following the sixth position in an ordering or series; coming next after the sixth and just before the eighth in position. (Source: NCI Thesaurus)

Immunocompromised
type: Class
subclass of: immune response
type: NamedIndividual
type: Quality Value
comment: This class denotes Immunocompromised
notation: HHEAR_374

Fungus
type: Class
subclass of: Eukaryota
type: NamedIndividual
type: NodeShape
comment: A kingdom of eukaryotic, heterotrophic organisms that live as saprobes or parasites, including mushrooms, yeasts, smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi refer to those that grow as multicellular colonies (mushrooms and molds). (Source: NCI Thesaurus)

Clinical Encounter
type: Class
subclass of: Event
comment: This class denotes Clinical Encounter

Legally Acceptable Representative
type: Class
subclass of: SIO_000287
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An individual or juridical or other body authorized under applicable law to consent, on behalf of a prospective subject, to the subject's participation in the clinical trial. (ICH) (Source: NCI Thesaurus)
alternative label: Legally Authorized Representative
notation: HHEAR_1117

Dietary Supplement
type: Class
subclass of: Drug, Food, Chemical or Biomedical Material
type: NamedIndividual
type: NodeShape
comment: Oral preparations containing dietary ingredient(s) intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites. (Source: NCI Thesaurus)

Hepatic Steatosis
type: Class
subclass of: Steatosis
type: NamedIndividual
type: NodeShape
comment: A morphologic finding indicating intracytoplasmic fat accumulation in the liver parenchyma. (Source: NCI Thesaurus)

Inpatient Encounter
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: A patient encounter where a patient is admitted to a hospital or equivalent facility.
notation: HHEAR_169

Short Stay
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: A patient encounter where the patient is admitted to a health care facility for a predetermined length of time, usually less than 24 hours. [def-source:
notation: HHEAR_170

Testing
type: Class
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: A procedure for critical evaluation.

Transplantation
type: Class
subclass of: Comorbidity Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Transplantation
notation: HHEAR_401

Postmenopausal
type: Class
subclass of: Menopause Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: After menopause. (Source: NCI Theasurus)
notation: HHEAR_1062

Other Gender
type: Class
subclass of: Gender
type: NamedIndividual
type: Quality Value
comment: This class denotes Other Gender
notation: HHEAR_325

Hormone Therapy
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: NodeShape
comment: Various treatment modalities that produce the desired therapeutic effect by means of change of hormone/hormones level. (Source: NCI Thesaurus)

NIH Toolbox
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A comprehensive set of neuro-behavioral measures that assess cognitive, emotional, sensory, and motor functions, designed to be run on an iPad. (Source: NCI Thesaurus)

Focus Group
type: Class
subclass of: SIO_000620
type: NamedIndividual
type: NodeShape
comment: A small, usually diverse group of people whose response to something is studied to determine the response that can be expected from a larger population. It is used especially in market research and political analysis. (Source: NCI Thesaurus)

Step Father
type: Class
subclass of: Step Parent
subclass of: Father
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male that is related to a child or children through marriage to their biological parent. (Source: NCI Thesaurus)
notation: HHEAR_657

Premenopausal
type: Class
subclass of: Menopause Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Prior to menopause. (Source: NCI Theasurus)
notation: HHEAR_1061

Perimenopausal
type: Class
subclass of: Menopause Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Describes the time in a woman's life as she approaches menopause. This is usually three to five years before menopause and is often marked by irregular menstrual periods and many of the symptoms of menopause, including hot flashes, mood swings, night sweats, vaginal dryness, trouble concentrating, and infertility. (Source: NCI Theasurus)
notation: HHEAR_1063

Classroom
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A room or space, especially in a school, where classes are held. (Source: NCI Thesaurus)
notation: HHEAR_967

Raw Score
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
disjoint with: Adjusted Score
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Raw Score

Mobile Home
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: Quality Value
comment: This class denotes Mobile Home
notation: HHEAR_247

Rented Room
type: Class
subclass of: Living Quarters
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A room within a larger dwelling used as an individual living space in exchange for money. (Source: NCI Thesaurus)
notation: HHEAR_964

Experimental Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
definition: A study population that receives the intervention that is the focus of the study.
notation: HHEAR_201

Validation
type: Class
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: The act of validating; finding or testing the truth of something. (Source: NCI Theasurus)

Teenager
type: Class
subclass of: Demographic
subclass of: Developmental Quality
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: An individual between the ages of 13 and 19.
notation: HHEAR_137

Black or African American
type: Class
subclass of: Non-White
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used in addition to "Black or African American".
notation: HHEAR_8

Destination
type: Class
subclass of: Healthcare Access
type: NamedIndividual
type: Quality Variable
definition: A place to which one is traveling or to which something is sent.
notation: Dest

Home Observation for Measurement of the Environment, Revised Edition
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A 38-item questionnaire that evaluates the quality of a child's home environment filled out by the child's primary caregiver. The questions vary based on the age of the child.

Female Cousin
type: Class
subclass of: Cousin
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female child of one's aunt or uncle. (Source: NCI Thesaurus)
notation: HHEAR_660

Male Cousin
type: Class
subclass of: Cousin
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male child of one's aunt or uncle. (Source: NCI Thesaurus)
notation: HHEAR_661

Biological Parent
type: Class
subclass of: Biological Relative
subclass of: Parent
type: NamedIndividual
type: NodeShape
comment: The male who supplied the sperm or the female who supplied the egg which resulted in one's conception. (Source: NCI Thesaurus)

Step Parent
type: Class
subclass of: Step
subclass of: Parent
type: NamedIndividual
type: NodeShape
comment: A non-biological parent through current or prior marriage to the subject's biological or legal parent. (Source: NCI Thesaurus)

Adoptive Parent
type: Class
subclass of: Parent
type: NamedIndividual
type: NodeShape
comment: A parent in the parent-child relationship established by a legal adoption proceeding. (Source: NCI Thesaurus)

Adoptive Father
type: Class
subclass of: Adoptive Parent
subclass of: Father
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male parent in the parent-child relationship established by a legal adoption proceeding. (Source: NCI Thesaurus)
notation: HHEAR_659

Adoptive Mother
type: Class
subclass of: Adoptive Parent
subclass of: Mother
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female parent in the parent-child relationship established by a legal adoption proceeding. (Source: NCI Thesaurus)
notation: HHEAR_658

Hospital
type: Class
subclass of: Healthcare Facility
comment: This class denotes Hospital

Medical Device
type: Class
subclass of: Physical Instrument
type: NamedIndividual
type: NodeShape
comment: Any physical object that is useful for prevention, diagnosis, monitoring, or treatment of disease or other conditions. [Definition Source: NCI]

Population Group
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Quality Variable
definition: A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender)

days per week
type: Class
subclass of: rate unit
type: NamedIndividual
type: NodeShape
comment: This class denotes days per week

Hours Per Week
type: Class
subclass of: Temporal Frequency
type: NamedIndividual
type: NodeShape
comment: A unit of measurement equal to the number of hours within a period of time equal to one week. (Source: NCI Thesaurus)

respiration
type: Class
subclass of: SIO_000006
comment: This class denotes respiration

Weather
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: Facet
type: NodeShape
comment: The state of the atmosphere at a given time and place, with respect to variables such as temperature, moisture, wind velocity, and barometric pressure. (Source: NCI Thesaurus)

school
type: Class
subclass of: Organization
type: NamedIndividual
type: NodeShape
comment: An educational institution.

Medical Leave
type: Class
subclass of: Occupation
type: NamedIndividual
type: Quality Value
comment: This class denotes Medical Leave
notation: HHEAR_246

Dietary Calories Measurement
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: This class denotes Dietary Calories Measurement

Vital Statistics
type: Class
subclass of: SIO_000088
type: NamedIndividual
type: NodeShape
comment: Government records of live births, fetal deaths, marriages, divorces, and deaths that occur within that jurisdiction. (Source: NCI Thesaurus)

Gender
type: Class
subclass of: Demographic
type: NamedIndividual
type: Quality Variable
type: Facet
comment: This class denotes Gender

Hispanic or Latino Ethnicity
type: Class
subclass of: SIO_001014
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term “Spanish origin” can also be used in addition to “Hispanic or Latino.”
notation: HHEAR_47

Agreement Answer
type: Class
subclass of: SIO_000965
type: NamedIndividual
type: NodeShape
comment: A response about an individual's agreement about something. [Definition Source: NCI]

hours per day
type: Class
subclass of: rate unit
type: NamedIndividual
type: NodeShape
comment: This class denotes hours per day

Physical Activity
type: Class
subclass of: Physical Activity and Fitness
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Physical Activity

Home
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: A person's place of residence.
notation: HHEAR_167

Diagnostic Procedure
type: Class
equivalent class: SIO_001022
subclass of: SIO_001024
type: NamedIndividual
type: NodeShape
comment: Any procedure or test to diagnose a disease or disorder. A specific test or series of steps done to help diagnose a disease or condition. Mammograms and colonscopies (sp) are examples of diagnostic procedures. (Source: NCI Thesaurus)

Non-Alcoholic Fatty Liver Disease Activity Score
type: Class
subclass of: Research or Clinical Assessment Tool
subclass of: Restriction
  on property: SIO_000668
  some values from: non-alcoholic fatty liver disease
type: NamedIndividual
type: NodeShape
comment: The histopathological evaluation of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) based on the NAFLD scoring system. (Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh M, McCullough AJ, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005 Jun;41(6):1313-21.) (Source: NCI Thesaurus)

Portal Inflammation Assessment
type: Class
subclass of: Histopathologic Examination
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: An evaluation of the presence or degree of portal inflammation in a sample.

Hepatocellular Ballooning Assessment
type: Class
subclass of: Histopathologic Examination
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: An evaluation of the presence or degree of hepatocellular ballooning in a sample. (Source: NCI Thesaurus)

Mallory Body Assessment
type: Class
subclass of: Histopathologic Examination
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: An evaluation of the presence or degree of mallory bodies in a sample.

Screening Test
type: Class
subclass of: Test
comment: This class denotes Screening Test

Histopathologic Examination
type: Class
subclass of: Medical Examination
type: NamedIndividual
type: NodeShape
comment: The microscopic study of characteristic tissue abnormalities by employing various cytochemical and immunocytochemical stains. (Source: NCI Thesaurus)

Stool Sample
type: Class
subclass of: feces
subclass of: Biospecimen
type: NamedIndividual
type: Facet
type: NodeShape
comment: A fecal biospecimen. (Source: NCI Thesaurus)

T-Cell Activation
type: Class
subclass of: immune response
type: NamedIndividual
type: NodeShape
comment: T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in biosynthesis of lymphokines, cell proliferation, cell differentiation, and maturation to support immune activity. (Source: NCI Thesaurus)

Drug, Food, Chemical or Biomedical Material
type: Class
subclass of: Thing
type: NamedIndividual
type: NodeShape
comment: An organic or inorganic substance, element, isotope, food or other materials derived from microorganism, plant, or animal sources. They can be used for the prevention, diagnosis, treatment or research of disease states, for industrial purposes, or for the promotion or maintenance of organism viability or health. (Source: NCI Thesaurus)

B-Cell Activation
type: Class
subclass of: immune response
type: NamedIndividual
type: NodeShape
comment: A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation. (Source: NCI Thesaurus)

Protein Family
type: Class
subclass of: SIO_010043
type: NamedIndividual
type: NodeShape
comment: Collection of proteins that are evolutionarily related. This is reflected in the structural and functional similarities as well as in the extent of sequence conservation or residue identity. (from SCOP)

Conceptual Entity
type: Class
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: An organizational header for concepts representing mostly abstract entities. (Source: NCI Thesaurus)

Research or Clinical Assessment Tool
type: Class
subclass of: Assessment
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: Any evaluation or assessment tool used to ascertain a patient's condition or diagnosis. [Definition Source: NCI]

Healthcare Facility
type: Class
subclass of: Workplace
subclass of: Organization
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The buildings and organizations where healthcare services are provided.
notation: HHEAR_973

Dietary Lipid
type: Class
subclass of: Diet and Nutrition
type: NamedIndividual
type: NodeShape
comment: A class of food constituents, also known as fats and oils, that serve as a source of energy and essential fatty acids in animals. The major components of lipids are fatty acids, triglycerides, phospholipids, glycolipids, sphingolipids, steroids (cholesterol), and lipoproteins. [ NCI ]

Employment
type: Class
subclass of: Occupation
subclass of: Employment Status
type: NamedIndividual
type: Quality Value
comment: The state of being engaged in an activity or service for wages or salary. (Source: NCI Thesaurus)
notation: HHEAR_245

Measurement
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quality Variable
comment: This class denotes Measurement

Assessment
type: Class
subclass of: Analytical Method
type: NamedIndividual
type: NodeShape
comment: A measurement, evaluation, or judgment for a study variable pertaining to the status of a subject.

Third
type: Class
subclass of: Ordinal Position
comment: Following the second position in an ordering or series; coming next after the second and just before the fourth in position. (Source: NCI Thesaurus)

Neurologic
type: Class
subclass of: SIO_000475
type: NamedIndividual
type: Quality Value
comment: This class denotes Neurologic
notation: HHEAR_396

Residence
type: Class
subclass of: Housing Characteristic
type: NamedIndividual
type: NodeShape
comment: Any address at which a person dwells more than temporarily. (Source: NCI Theasurus)

Cardiovascular
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Facet
type: NodeShape
comment: Pertaining to the heart or blood vessels. (Source: NCI Thesaurus)

Medical Examination
type: Class
subclass of: Diagnostic Procedure
type: NamedIndividual
type: NodeShape
comment: An appraisal or evaluation of a patient's condition by a clinician that is based on a physical exam, medical history, and the patient's account of symptoms. (Source: NCI Thesaurus)

Admission
type: Class
subclass of: Activity
comment: This class denotes Admission

Event
type: Class
subclass of: Conceptual Entity
type: NamedIndividual
type: NodeShape
comment: Something that happens at a given place and time. (Source: NCI Thesaurus)

First
type: Class
subclass of: Ordinal Position
comment: Preceding all others in time or space or degree. (Source: NCI Thesaurus)

Temporal Frequency
type: Class
subclass of: frequency unit
type: NamedIndividual
type: NodeShape
comment: The number of occurrences of something within a given time period. (Source: NCI Thesaurus)

Breast Feeding
type: Class
subclass of: Feeding Method
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The nursing of an infant at the mother's breast. [Definition Source: NCI]
notation: HHEAR_677

Second
type: Class
subclass of: Ordinal Position
comment: Coming next after the first in position in space or time or degree or magnitude (Source: NCI Thesaurus)

Urination
type: Class
subclass of: Biological Response
subclass of: Targeted Analyte
type: NamedIndividual
type: Quality Variable
comment: This class denotes Urination

Eukaryota
type: Class
subclass of: SIO_010000
type: NamedIndividual
type: NodeShape
comment: Organism or cells with a nucleus separated from the cytoplasm by a two membrance nuclear envelope and compartmentalization of function into distinct cytoplasmic organelles. (Source: NCI Thesaurus)

Mouse Stool
type: Class
subclass of: SIO_010051
type: NamedIndividual
type: NodeShape
comment: This class denotes Mouse Stool

Infectious Disorder
type: Class
subclass of: Disease
type: NamedIndividual
type: Facet
comment: This class denotes Infectious Disorder

Non-Neoplastic Lung Disorder
type: Class
subclass of: SIO_000475
comment: This class denotes Non-Neoplastic Lung Disorder

Control Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
definition: A group used as a standard of comparison in a control experiment.
notation: HHEAR_200

Congenital Abnormality
type: Class
subclass of: Disease
subclass of: Congenital anomaly or chromosomal defect
type: NamedIndividual
type: Quality Value
comment: This class denotes Congenital Abnormality
notation: HHEAR_1076

Dead
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: The cessation of life.
notation: HHEAR_173

Dimenhydrinate
type: Class
subclass of: SIO_010039
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An ethanolamine and first-generation histamine antagonist with anti-allergic activity. Dimenhydrinate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, GI smooth muscle spasm. (Source: NCI Thesaurus)
notation: HHEAR_1218

Ferrous sulfate
type: Class
subclass of: HHEAR 2348
type: NamedIndividual
type: NodeShape
comment: A sulfate salt of mineral iron formulated for oral administration and used as a dietary supplement, ferrous sulfate is absorbed in the stomach and small intestine and combines with apoferritin to form ferritin, which is stored in the liver, spleen, red bone marrow, and intestinal mucosa. Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is a component of many enzymes such as catalase, peroxidase, and cytochromes. (Source: NCI Thesaurus)

Airborne Particulate Matter
type: Class
subclass of: Air Pollutant
type: NamedIndividual
type: Quality Variable
comment: This class denotes Airborne Particulate Matter

Digestive System Disorder
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Digestive System Disorder
notation: HHEAR_392

Menarche
type: Class
subclass of: biological_process
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: Onset of menses. (Source: NCI Thesaurus)

Menopause
type: Class
subclass of: biological_process
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age. (Source: NCI Thesaurus)

Finding
type: Class
subclass of: SIO_001394
type: NamedIndividual
type: NodeShape
comment: Clinical, laboratory or molecular evidence, or absence of evidence of disease. (Source: NCI Thesaurus)

Perinatal Disorder
type: Class
subclass of: Pediatric Disorder
type: NamedIndividual
type: NodeShape
comment: A non-neoplastic or neoplastic disorder occurring during the period from about five months before birth to one month after birth. (Source: NCI Thesaurus)

Lower Respiratory Tract Infection
type: Class
subclass of: infection
type: NamedIndividual
type: Quality Value
comment: This class denotes Lower Respiratory Tract Infection
notation: HHEAR_384

antepartum hypertension
type: Class
subclass of: hypertension
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes antepartum hypertension
notation: HHEAR_691

Mallory Bodies Present
type: Class
subclass of: Morphologic Finding
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A morphologic finding indicating the presence of Mallory bodies in the liver parenchyma. Mallory bodies are eosinophilic cytoplasmic inclusions in the hepatocytes. They contain filaments and are present in the liver parenchyma of patients with various liver disorders including alcoholic liver disease, Wilson disease, and primary biliary cirrhosis. (Source: NCI Thesaurus)
notation: HHEAR_757

Upper Respiratory Tract Infection
type: Class
subclass of: infection
type: NamedIndividual
type: Quality Variable
comment: This class denotes Upper Respiratory Tract Infection

postpartum hypertension
type: Class
subclass of: hypertension
type: NamedIndividual
type: NodeShape
comment: This class denotes postpartum hypertension

Morphologic Finding
type: Class
subclass of: Histopathology Result
type: NamedIndividual
type: NodeShape
comment: A light microscopic finding that describes the cellular characteristics and architectural patterns of cell populations in a tissue sample. (Source: NCI Thesaurus)

Steatosis
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: NodeShape
comment: Acumulation of adipose tissue in intracytoplasmic or extracellular spaces. (Source: NCI Thesaurus)

Laboratory Test Result
type: Class
subclass of: Finding
type: NamedIndividual
type: NodeShape
comment: The outcome of a laboratory test. (Source: NCI Thesaurus)

Catheterization
type: Class
subclass of: SIO_001024
comment: This class denotes Catheterization

Pulmonary Function Test
type: Class
subclass of: Diagnostic Procedure
type: NamedIndividual
type: NodeShape
comment: A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Source: NCI Thesaurus]

Clotrimazole
type: Class
subclass of: SIO_010039
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A synthetic, imidazole derivate with broad-spectrum, antifungal activity. Clotrimazole inhibits biosynthesis of sterols, particularly ergosterol, an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in leakage and loss of essential intracellular compounds, and eventually causes cell lysis. (Source: NCI Thesaurus)
notation: HHEAR_1215

Hypoxia
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Hypoxia
notation: HHEAR_923

Adolescence
type: Class
subclass of: Life Stage
subclass of: Childhood
type: NamedIndividual
type: Facet
type: NodeShape
comment: A human life stage that begins at twelve years of age and continues until twenty-one complete years of age, generally marked by the beginning of puberty and lasting to the beginning of adulthood.

Doctorate Degree
type: Class
subclass of: Completed Graduate School
type: NamedIndividual
type: Quality Value
definition: The Doctor's Degree is the highest award a student can earn for graduate study. The doctor's degree classification includes such degrees in any field.
notation: HHEAR_144

Master's Degree
type: Class
subclass of: Completed Graduate School
type: NamedIndividual
type: Quality Value
definition: The Master's Degree is an award that requires the successful completion of a program of study of at least the full-time equivalent of 1 but not more than two academic years of work beyond the bachelor's degree.
notation: HHEAR_143

Native Hawaiian or Other Pacific Islander
type: Class
subclass of: Non-White
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands.
notation: HHEAR_55

American Indian Or Alaskan Native
type: Class
subclass of: Non-White
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal affiliation or community attachment.
notation: HHEAR_5

Asian
type: Class
subclass of: Non-White
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam.
notation: HHEAR_6

White
type: Class
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
notation: HHEAR_102

Atopy
type: Class
subclass of: SIO_010056
comment: A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms. [Definition Source: NCI]
notation: HHEAR_361

Ohm
type: Class
subclass of: Unit of Electric Resistance
type: NamedIndividual
type: NodeShape
comment: A unit of electrical resistance equal to the resistance between two points on a conductor when a potential difference of one volt between them produces a current of one ampere. Ohm is also used to measure impedance and reactance for complex resistance. A measurement in ohms is the reciprocal of a measurement in siemens. (Source: NCI Thesaurus)

Hmong
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes a person having origins in any of the original Hmong people originating in China around the Yellow River or Hoang Ho.(Source: NCI Thesaurus)
notation: HHEAR_1223

Thai
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes the inhabitants of Thailand, a person from there, or their descendants elsewhere. (Source: NCI Thesaurus)
notation: HHEAR_1222

Bioelectric Impedance Analysis
type: Class
subclass of: Diagnostic Procedure
type: NamedIndividual
type: NodeShape
comment: A method to assess body composition, i.e., the relative percentages of body weight comprised of fat tissue and lean body mass. It is based on the principle that the resistance to an applied electric current is inversely related to the amount of lean body mass within the body. Impedance is greatest in fat tissue, which contains only 10-20% water, while lean body mass, which contains 70-75% water, allows the signal to pass much more easily. (Source: NCI Thesaurus)

Burmese
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes the inhabitants of Myanmar (formerly Burma), a person from there, or their descendants elsewhere. (Source: NCI Thesaurus)
notation: HHEAR_1225

Tobacco Related Exposure
type: Class
subclass of: Environmental Exposure
comment: This class denotes Tobacco Related Exposure

Medication
type: Class
subclass of: Prescription Medication and Dietary Supplements
type: NamedIndividual
type: Quality Variable
definition: A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product.
notation: HHEAR_142

Male Gender
type: Class
subclass of: Gender
type: NamedIndividual
type: Quality Value
comment: This class denotes Male Gender
notation: HHEAR_323

Female Gender
type: Class
subclass of: Gender
type: NamedIndividual
type: Quality Value
comment: This class denotes Female Gender
notation: HHEAR_324

Ordinal Position
type: Class
subclass of: Thing
comment: This class denotes Ordinal Position

Test
type: Class
subclass of: Analytical Method
comment: This class denotes Test

Transfer
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: The act of conveying or transporting from one place to another.
notation: HHEAR_172

Nested Case-control Study
type: Class
subclass of: SIO_001066
type: NamedIndividual
type: NodeShape
comment: A study in which a group or cohort of individuals is followed for a certain length of time or until a specific outcome is reached. Studies of this type incorporate the strengths of both cohort and case-control studies but eliminates a portion of the methodologic challenges inherent in both types of studies. (Source: NCI Thesaurus)

Stillbirth
type: Class
subclass of: Pregnancy Outcome By Fetal Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A fetus of at least 20 weeks gestation, or of a birth weight of at least 350 grams if the gestational age is unknown, that is born without signs of life at the time of delivery, and with an Apgar score of zero at both one and five minutes. (Source: NCI Thesaurus)
notation: HHEAR_1084

Diagnosis Group
type: Class
subclass of: Demographic
subclass of: Health Outcome
type: NamedIndividual
type: Quality Variable
comment: This class denotes Diagnosis Group

Beats per Minute
type: Class
subclass of: counts per minute
type: NamedIndividual
type: SIO_000074
type: NodeShape
comment: The number of heartbeats measured per minute time. [Definition Source: NCI]

Abrasion
type: Class
subclass of: SIO_000475
type: NamedIndividual
type: Quality Value
comment: This class denotes Abrasion
notation: HHEAR_387

Diabetic Ketoacidosis
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Diabetic Ketoacidosis
notation: HHEAR_391

Endotoxin
type: Class
subclass of: toxin
comment: This class denotes Endotoxin

Married
type: Class
subclass of: Marital Status
subclass of: Married or living together with partner
type: NamedIndividual
type: Quality Value
definition: Indicates a person currently joined in a legally binding matrimonial union. Classify common law marriage as married. Includes married couples living together and not living together.
notation: HHEAR_37

Never Married
type: Class
subclass of: Unmarried
type: NamedIndividual
type: Quality Value
definition: Indicates a person who has never been married or whose marriages have been annulled.
notation: HHEAR_38

Widowed
type: Class
subclass of: Unmarried
type: NamedIndividual
type: Quality Value
definition: Indicates a person who is no longer married because of the death of his/her spouse and has not remarried.
notation: HHEAR_39

Divorced
type: Class
subclass of: Unmarried
type: NamedIndividual
type: Quality Value
definition: Indicates a person whose marriage has been legally dissolved and has not remarried.
notation: HHEAR_40

Separated
type: Class
subclass of: Married
type: NamedIndividual
type: Quality Value
definition: Indicates a person living apart from his/her spouse by legal arrangement.
notation: HHEAR_41

Full Time Employment
type: Class
subclass of: Occupation
type: NamedIndividual
type: Quality Value
definition: Employed for a standard number of hours of working time, at least 50% or 20 hours per week.
notation: HHEAR_64

Domestic Partnership
type: Class
subclass of: Unmarried
subclass of: Married or living together with partner
type: NamedIndividual
type: Quality Value
definition: Indicates a person who is a member of an unmarried couple, including same sex couples, living together in longstanding relationships, that are registered or unregistered.
notation: HHEAR_42

Departure
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: The act of leaving a destination.
notation: HHEAR_174

Intensive Care Unit
type: Class
subclass of: Destination
subclass of: Healthcare Facility
type: NamedIndividual
type: Quality Value
definition: A health care facility unit that provides intensive care to critically ill patients and patients with complex medical problems who require constant monitoring or special therapy.
notation: HHEAR_168

Operating Room
type: Class
subclass of: Destination
type: NamedIndividual
type: Quality Value
definition: A room in a health care facility equipped for the performance of surgical operations and procedures.
notation: HHEAR_171

Emergency Medical Services Facility
type: Class
subclass of: Healthcare Facility
comment: This class denotes Emergency Medical Services Facility

Fourth
type: Class
subclass of: Ordinal Position
comment: Following the third position in an ordering or series; coming next after the third and just before the fifth in position. (Source: NCI Thesaurus)

Fifth
type: Class
subclass of: Ordinal Position
comment: Following the fourth position in an ordering or series; coming next after the fourth and just before the sixth in position. (Source: NCI Thesaurus)

Sixth
type: Class
subclass of: Ordinal Position
type: NamedIndividual
type: NodeShape
comment: Following the fifth position in an ordering or series; coming next after the fifth and just before the seventh in position. (Source: NCI Thesaurus)

Metoclopramide
type: Class
subclass of: SIO_010039
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A substituted benzamide and a derivative of para-aminobenzoic acid (PABA) that is structurally related to procainamide, with gastroprokinetic and antiemetic effects. Metoclopramide exerts its prokinetic effect by antagonizing dopamine mediated relaxation effect on gastrointestinal smooth muscle. This enhances the response of the gastrointestinal smooth muscle to cholinergic stimulation, thereby leading to an increase of gastric emptying into the intestines. Metoclopramide may also strengthen the lower esophagus sphincter, thereby preventing acid reflux. This agent antagonizes D2 dopamine receptors in chemoreceptive trigger zone (CTZ) of the medulla, thereby preventing nausea and vomiting. (Source: NCI Thesaurus)
notation: HHEAR_1216

Apartment
type: Class
subclass of: Living Quarters
type: NamedIndividual
type: Quality Value
comment: This class denotes Apartment
notation: HHEAR_196

Allergen
type: Class
subclass of: Drug, Food, Chemical or Biomedical Material
subclass of: Environmental Exposure
comment: A substance that elicits an allergic reaction. (Source: NCI Thesaurus)

Questionnaire Administration
type: Class
subclass of: SIO_001052
type: NamedIndividual
type: NodeShape
comment: This class denotes Questionnaire Administration

Laboratory Biomarker Analysis
type: Class
subclass of: SIO_000999
type: NamedIndividual
type: NodeShape
comment: This class denotes Laboratory Biomarker Analysis

Multiracial
type: Class
subclass of: Non-White
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Having ancestors of several or various races.
editorial note: Not part of current prov for Race. Should we remove this concept?
notation: HHEAR_54

Multiple Hispanic
type: Class
subclass of: Hispanic or Latino Ethnicity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person living in the United States of Mexican, Puerto Rican, Cuban, Central or South American, or other Spanish culture or origin. The concept does not include Brazilian Americans or Portuguese Americans. (Source: NCI Thesaurus)
notation: HHEAR_673

Puerto Rican
type: Class
subclass of: Hispanic or Latino Ethnicity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person of Puerto Rican culture or origin, regardless of race. (Source: NCI Thesaurus)
notation: HHEAR_672

Mexican
type: Class
subclass of: Hispanic or Latino Ethnicity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes a person from or of Mexico. (Source: NCI Thesaurus)
notation: HHEAR_670

Some College
type: Class
subclass of: Post-Secondary Education
subclass of: Some College or Technical School
subclass of: High School or Some College
subclass of: Some College or Trade School Graduate
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Indicates that a person has attended college but that they did not receive any degree.
notation: HHEAR_85

nanogram per gram
type: Class
subclass of: concentration unit
type: NamedIndividual
type: SIO_000074
type: NodeShape
comment: The unit of measure nanogram per gram
notation: ng/g

Microunit per Milliliter
type: Class
subclass of: unit per volume unit
type: NamedIndividual
type: NodeShape
comment: An arbitrary unit of substance concentration equal to the concentration at which one milliliter of mixture contains one millionth of a unit of a substance. (Source: NCI Thesaurus)

Unit of Electric Resistance
type: Class
subclass of: unit
type: NamedIndividual
type: NodeShape
comment: A unit for measurement of property of any object or substance of resisting or opposing the flow of an electrical current. (Source: NCI Thesaurus)

Room
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: Quality Value
comment: This class denotes Room
notation: HHEAR_249

Household Income
type: Class
subclass of: Socioeconomic Status
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
type: Facet
was approved by: PER-Jeanette-Stingone
definition: A demographic parameter indicating the amount of earnings made by a family.

Quotient
type: Class
subclass of: SIO_000075
comment: This class denotes Quotient

Pack Year
type: Class
subclass of: unit
type: NamedIndividual
type: NodeShape
comment: A quantification of lifetime tobacco exposure defined as (number of cigarettes smoked per day x number of years smoked)/20. One pack-year is smoking 20 cigarettes a day for one year. (Source: NCI Thesaurus)

Nucleated Red Blood Cell Count
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: NodeShape
comment: The determination of the number of nucleated red blood cells present in a sample. (Source: NCI Thesaurus)

Homemaker
type: Class
subclass of: Occupation
type: NamedIndividual
type: Quality Value
definition: A person who manages a home as their main daily activity.
notation: HHEAR_68

Student
type: Class
subclass of: Occupation
subclass of: Education
type: NamedIndividual
type: Quality Value
comment: This class denotes Student
notation: HHEAR_66

Part Time Employment
type: Class
subclass of: Occupation
type: NamedIndividual
type: Quality Value
definition: Employment involving less than the standard or customary working time.
notation: HHEAR_65

Unemployment
type: Class
subclass of: Occupation
subclass of: Employment Status
type: NamedIndividual
type: Quality Value
definition: The state of not having a job.
notation: HHEAR_67

Annulled
type: Class
subclass of: Never Married
type: NamedIndividual
type: Quality Value
definition: A marital status in which a voidable marriage is legally declared null and void, as though it never existed. Specific grounds for annullment vary within the presiding jurisdiction, whether geographic or religious.
notation: HHEAR_43

Interlocutory Marital Status
type: Class
subclass of: Marital Status
type: NamedIndividual
type: Quality Value
definition: The condition existing when an order or judgement is considered temporary until either a specified period of time has passed or specific information is provided to assist in rendering a permanent decision.
notation: HHEAR_44

Polygamous
type: Class
subclass of: Marital Status
type: NamedIndividual
type: Quality Value
definition: A type of living arrangement or mating system in which at least one member of a relationship has more than one mate.
notation: HHEAR_45

Aspergillus
type: Class
subclass of: Fungus
comment: This class denotes Aspergillus

Neonatal Death
type: Class
subclass of: Birth Outcome
subclass of: Pregnancy Outcome By Fetal Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Death of a live newborn during the first 28 days of life. (Source: NCI Thesaurus)
notation: HHEAR_1064

Meal
type: Class
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: Any of the occasions for eating food that occur by custom or habit at more or less fixed times.

Breakfast
type: Class
subclass of: Meal
type: NamedIndividual
type: NodeShape
comment: The first meal of the day (usually in the morning).

Lunch
type: Class
subclass of: Meal
type: NamedIndividual
type: NodeShape
comment: A midday meal sometimes also called dinner.

Supper
type: Class
subclass of: Meal
type: NamedIndividual
type: NodeShape
comment: The evening meal, usually the main meal of the day.

Cognitive Development
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Facet
type: NodeShape
comment: The evolution of an individual's problem solving skills, memory, language development, and ability to process information about their environment. (Source: NCI Thesaurus)

Feeding Method
type: Class
subclass of: nutrition intake
type: NamedIndividual
type: NodeShape
comment: A description of the technique for the manner in which a subject is administered food. [Definition Source: NCI]

Bottle Feeding
type: Class
subclass of: Feeding Method
type: NamedIndividual
type: NodeShape
comment: Provision of liquid nutrition via a closed container system with a rubber like mouthpiece resembling a nipple. [Definition Source: NCI]

Tanner Scale
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A scale of physical development in children, adolescents and adults based on external primary and secondary sex characteristics, such as the size of the breasts, genitalia, and development of pubic hair. [Definition Source: NCI][attribution: Tanner JM. Growth at adolescence. 2d ed. Oxford: Blackwell, 1962]

English Language
type: Class
subclass of: Acculturation
type: NamedIndividual
type: Quality Value
definition: The English Language
notation: HHEAR_243

Visit Date
type: Class
subclass of: Demographic
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: The date on which a visit occurred. (Source: NCI Thesuarus)

Histopathology Result
type: Class
subclass of: Pathology Result
type: NamedIndividual
type: NodeShape
comment: A finding resulting from the examination of a tissue sample under light or electron microscopy. (Source: NCI Thesaurus)

Spirometry
type: Class
subclass of: Pulmonary Function Test
type: NamedIndividual
type: NodeShape
comment: Measurement of the breathing capacity of the lung by means of a spirometer. (Source: NCI Thesaurus)

Chief Complaint
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Quality Variable
comment: This class denotes Chief Complaint

Living Quarters
type: Class
subclass of: Human Dwelling
comment: Housing in which people can reside. (Source: NCI Thesaurus)

Kitchen
type: Class
subclass of: Room
subclass of: Living Room or Child's Bedroom or Kitchen
type: NamedIndividual
type: NodeShape
comment: This class denotes Kitchen

hypertonia
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A condition of increased muscle tone manifested by increased resistance of the muscle to passive stretching. (Source: NCI Thesaurus)
notation: HHEAR_961

Pediatric Disorder
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: NodeShape
comment: A non-neoplastic or neoplastic disorder which occurs during infancy, childhood, or adolescence. (Source: NCI Thesaurus)

Life Stage
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000417
type: NamedIndividual
type: Facet Category
type: NodeShape
comment: A designation assigned to a particular period during a life cycle, generally defined by chronological parameters. (Source: NCI Thesaurus)

Childhood
type: Class
subclass of: Life Stage
subclass of: Demographic
subclass of: Developmental Quality
type: NamedIndividual
type: Quality Value
type: Facet
was approved by: PER-Jeanette-Stingone
definition: A time period that begins at the beginning of the human embryonic stage and continues until the end of adolescence.
notation: HHEAR_11

Early Childhood
type: Class
subclass of: Life Stage
subclass of: Childhood
type: NamedIndividual
type: Facet
type: NodeShape
comment: A human life stage that begins at two years of age and continues until five complete years of age. [Definition Source: NCI][attribution: NICHD]

Middle Childhood
type: Class
subclass of: Life Stage
subclass of: Childhood
type: NamedIndividual
type: NodeShape
comment: A human life stage that begins at six years of age and continues until eleven complete years of age. [Definition Source: NCI][attribution: NICHD]

Perceived Stress Scale
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A 10-item self-report questionnaire that measures a person's evaluation of the stressfulness of life situations in the past month. Each item is rated 0-4 on a 5-point Likert scale. (Cohen, et al, J Health Soc Behav, 24 (1983)) (Source: NCI Thesaurus)

Maternal Prenatal Stage
type: Class
subclass of: Life Stage
type: NamedIndividual
type: NodeShape
comment: The stage in the life of a mother during which she is pregnant. (Source: NCI Thesaurus)

Pregnancy Outcome
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Facet
type: NodeShape
comment: Findings observed at the end of a pregnancy. (Source: NCI Thesaurus)

Bronchopulmonary Dysplasia
type: Class
subclass of: lung disease
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Chronic lung disease requiring treatment with oxygen for at least 28 days and with a spectrum of severity from mild to severe, that predominantly affects premature infants. While the radiologic pattern is typical in the closer to term patient, the pattern in the small preterm infant is very non-discrete and variable. (Source: NCI Thesaurus)
notation: HHEAR_1175

Fetal Disorder
type: Class
subclass of: Pediatric Disorder
type: NamedIndividual
type: NodeShape
comment: A non-neoplastic or neoplastic disorder which occurs in the fetus. (Source: NCI Thesaurus)

Advance Directive
type: Class
subclass of: Medical History
subclass of: SIO_000148
type: NamedIndividual
type: Quality Variable
comment: A legal document that states the treatment or care a person wishes to receive or not receive if he or she becomes unable to make medical decisions (for example, due to being unconscious or in a coma). Some types of advance directives are living wills and do-not-resuscitate (DNR) orders. (Source: NCI Thesaurus)

Probiotic
type: Class
subclass of: Dietary Supplement
type: NamedIndividual
type: NodeShape
comment: A live microorganism used as a dietary supplement to help with digestion and normal bowel function. It may also help keep the gastrointestinal (GI) tract healthy. A bacterium found in yogurt called Lactobacillus acidophilus, is the most common probiotic. (Source: NCI Thesaurus)

Do Not Resuscitate Order
type: Class
subclass of: Advance Directive
type: NamedIndividual
type: Quality Value
comment: This class denotes Do Not Resuscitate Order
notation: HHEAR_365

Birth Order
type: Class
subclass of: Birth Outcome
type: NamedIndividual
type: Quality Variable
comment: This class denotes Birth Order

Vitamin
type: Class
subclass of: Drug, Food, Chemical or Biomedical Material
comment: This class denotes Vitamin

Breath
type: Class
subclass of: Biospecimen
type: NamedIndividual
type: NodeShape
comment: The air that is inhaled and exhaled during respiration. [Definition Source: NCI]

Season
type: Class
subclass of: Weather
type: NamedIndividual
type: Quality Value
comment: This class denotes Season
notation: HHEAR_209

Winter
type: Class
subclass of: Season
type: NamedIndividual
type: Quality Value
comment: This class denotes Winter
notation: HHEAR_210

Spring
type: Class
subclass of: Season
type: NamedIndividual
type: Quality Value
comment: This class denotes Spring
notation: HHEAR_211

Summer
type: Class
subclass of: Season
type: NamedIndividual
type: Quality Value
comment: This class denotes Summer
notation: HHEAR_212

Fall
type: Class
subclass of: Season
type: NamedIndividual
type: Quality Value
comment: This class denotes Fall
notation: HHEAR_213

Systemic Inflammatory Response Syndrome
type: Class
subclass of: Sepsis, Septic Shock, or SIRS
subclass of: SIO_010056
comment: This class denotes Systemic Inflammatory Response Syndrome

Hounsfield Unit
type: Class
subclass of: UO_0000127
type: NamedIndividual
type: NodeShape
comment: The unit of measure for the radiodensity of a substance. The radiodensity of distilled water at standard temperature and pressure is zero on the Hounsfield scale. (Source: NCI Thesaurus)
notation: HU

Developmental Neuropsychological Assessment
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A series of neurocognitive tests for children from 3 to 16 years of age. NEPSY can be used for general, diagnostic, selective, or full assessment of neuropsychological development. (Copyright: Pearson Education, Inc; Marit Korkman, Ph.D., Ursula Kirk, Ph.D., and Sally Kemp, Ph.D., authors) (Source: NCI Thesaurus)

State-Trait Anxiety Inventory
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: An instrument for measuring anxiety. It is designed to differentiate between temporary "state anxiety" and general, long-standing "trait anxiety". (Copyright Mind Garden, Inc.) (Source: NCI Thesaurus)

Biological Father
type: Class
subclass of: Biological Parent
subclass of: Father
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male who contributes to the genetic makeup of his offspring through the fertilization of an ovum by his sperm. (Source: NCI Thesaurus)
notation: HHEAR_655

Biological Mother
type: Class
subclass of: Biological Parent
subclass of: Mother
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female who contributes to the genetic makeup of her offspring from the fertilization of her ovum. (Source: NCI Thesaurus)
notation: HHEAR_654

Immature Granulocyte Count
type: Class
subclass of: Immature Granulocytes Measurement
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The determination of the amount of immature granulocytes present in a sample.

Neonatal Disorder
type: Class
subclass of: Pediatric Disorder
type: NamedIndividual
type: NodeShape
comment: A non-neoplastic or neoplastic disorder which occurs during the neonatal period. (Source: NCI Thesaurus)

smoking behavior trait
type: Class
subclass of: Consumption Behavior
type: NamedIndividual
type: NodeShape
comment: The quality of a smoking behavior. (Source: OBA Ontology)

container
type: Class
subclass of: Thing
comment: This class denotes container

selection criterion
type: Class
subclass of: Thing
comment: This class denotes selection criterion

surface wipe
type: Class
subclass of: Environmental Material
type: NamedIndividual
type: NodeShape
comment: A sample collection device consisting of a thin, less absorbent sheet, used to collect material from surfaces. (Source: Ontology for Biomedical Investigations)

Hospitalization
type: Class
subclass of: Hospital Utilization
subclass of: SIO_001024
type: NamedIndividual
type: Quality Value
definition: Admission to a hospital
notation: HHEAR_104

Cockroach
type: Class
subclass of: SIO_010375
type: NamedIndividual
type: NodeShape
comment: This class denotes Cockroach

microbial phenotype
type: Class
subclass of: SIO_010056
comment: This class denotes microbial phenotype

Household
type: Class
subclass of: Housing Characteristic
subclass of: SIO_000016
definition: A household consists of one or more people who live in the same dwelling and also share meals or living accommodation, and may consist of a single family or some other grouping of people. A single dwelling will be considered to contain multiple households if either meals or living space are not shared. The household is the basic unit of analysis in many social, microeconomic and government models, and is important to the fields of economics and inheritance.

24-hour dietary recall
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: A structured interview intended to capture detailed information about all foods and beverages (and possibly, dietary supplements) consumed by the respondent in the past 24 hours, most commonly, from midnight to midnight the previous day. A key feature of the 24HR is that, when appropriate, the respondent is asked for more detailed information than first reported. For example, a respondent reporting chicken for dinner or a sandwich for lunch would be asked about the preparation method and type of bread. This open-ended response structure is designed to prompt respondents to provide a comprehensive and detailed report of all foods and beverages consumed. A 24h can also be filled at home by the responder, and be checked during an interview to further improve it with additional details. (Source: Ontology for Nutritional Studies)

duration
type: Class
subclass of: Thing
comment: This class denotes duration; A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point. (Source: PATO Ontology)

nulliparous
type: Class
subclass of: Thing
comment: A viviparous organism having never given birth. (Source: Phenotype and Trait Ontology)
notation: HHEAR_62

Parity
type: Class
subclass of: Pregnancy Characteristic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: The number of time that a viviparous organism has given birth

collection of organisms
type: Class
subclass of: SIO_000616
comment: This class denotes collection of organisms

community species diversity
type: Class
subclass of: SIO_000052
comment: This class denotes community species diversity

Shannon diversity index
type: Class
subclass of: community species diversity
subclass of: Physical And Mental Assessment
subclass of: Health Outcome
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Shannon diversity index

bone marrow proteoglycan proteolytic cleavage product
type: Class
subclass of: SIO_010363
type: NamedIndividual
type: NodeShape
comment: This class denotes bone marrow proteoglycan proteolytic cleavage product

SCD Genotype
type: Class
subclass of: SIO_001079
comment: This class denotes SCD Genotype

Hemoglobin Genotype SS
type: Class
subclass of: SCD Genotype
subclass of: SIO_001079
type: NamedIndividual
type: Quality Value
comment: This class denotes Hemoglobin Genotype SS
notation: HHEAR_346

Hemoglobin Genotype AS
type: Class
subclass of: SCD Genotype
subclass of: SIO_001079
type: NamedIndividual
type: Quality Value
comment: This class denotes Hemoglobin Genotype AS
notation: HHEAR_347

sequence_feature
type: Class
subclass of: SIO_000030
comment: This class denotes sequence_feature

sequence_attribute
type: Class
subclass of: SIO_000030
type: NamedIndividual
type: NodeShape
comment: This class denotes sequence_attribute

SNP
type: Class
subclass of: SNV
type: NamedIndividual
type: NodeShape
comment: SNPs are single base pair positions in genomic DNA at which different sequence alternatives exist in normal individuals in some population(s), wherein the least frequent variant has an abundance of 1% or greater.

sequence_alteration
type: Class
subclass of: allele
type: NamedIndividual
type: NodeShape
comment: A sequence_alteration is a sequence_feature whose extent is the deviation from another sequence.

sequence_variant
type: Class
subclass of: SIO_000030
type: NamedIndividual
type: NodeShape
comment: This class denotes sequence_variant

sequence_collection
type: Class
subclass of: SIO_000030
type: NamedIndividual
type: NodeShape
comment: This class denotes sequence_collection

SNV
type: Class
subclass of: substitution
type: NamedIndividual
type: NodeShape
comment: SNVs are single base pair positions in genomic DNA at which different sequence alternatives exist.

substitution
type: Class
subclass of: sequence_alteration
type: NamedIndividual
type: NodeShape
comment: Any change in genomic DNA caused by a single event.

Matched Pair of Subjects
type: Class
subclass of: SIO_000616
definition: A set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria

Z-Score
type: Class
subclass of: Anthropometry
definition: A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.

minimum value
type: Class
subclass of: measurement datum
comment: This class denotes minimum value

maximum value
type: Class
subclass of: measurement datum
comment: This class denotes maximum value

confidence interval
type: Class
subclass of: data item
comment: This class denotes confidence interval

percentile
type: Class
subclass of: Thing
type: NamedIndividual
type: SIO_000074
comment: a percentile is a quantile which splits data into sections accrued of 1% of data, so the first percentile delineates 1% of the data, the second quartile delineates 2% of the data and the 99th percentile, 99 % of the data (Source: Statistics Ontology)
notation: %

score
type: Class
subclass of: SIO_000075
comment: This class denotes score

neurological dysfunction
type: Class
subclass of: Comorbidity Disease
comment: This class denotes neurological dysfunction

septic shock
type: Class
subclass of: Sepsis, Septic Shock, or SIRS
subclass of: SIO_010056
comment: This class denotes septic shock

symptom
type: Class
subclass of: SIO_010056
comment: This class denotes symptom

Dysphagia
type: Class
subclass of: symptom
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: difficulty in swallowing
notation: HHEAR_1075

excessive crying of infant
type: Class
subclass of: symptom
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes excessive crying of infant
notation: HHEAR_960

stroke
type: Class
subclass of: Stroke, Cerebral Ischemia, or Cerebral infarction
subclass of: SIO_010056
comment: This class denotes stroke

reactive hyperemia
type: Class
subclass of: symptom
type: NamedIndividual
type: NodeShape
comment: Reactive hyperemia is a hyperemia occurring due to the dilation of arteriolar smooth muscle to increase blood flow in response to a profound increase in blood flow to an organ after being occluded. There will be a shortage of oxygen and a build-up of metabolic waste. (Source: Symptom Ontology)

Pathogen Transmission
type: Class
subclass of: SIO_000006
comment: This class denotes Pathogen Transmission

Head
type: Class
subclass of: SIO_010046
comment: This class denotes Head

Whole Blood
type: Class
subclass of: bodily fluid
type: NamedIndividual
type: Facet
definition: A fluid that is composed of blood plasma and erythrocytes. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Blood][database_cross_reference: https://github.com/obophenotype/uberon/issues/9][database_cross_reference: FMA:9670]

biological tissue
type: Class
subclass of: Thing
comment: This class denotes tissue

Abdomen
type: Class
subclass of: SIO_010046
comment: This class denotes Abdomen

Retina
type: Class
subclass of: SIO_010003
definition: The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.

Tibia
type: Class
subclass of: SIO_010046
definition: The major preaxial endochondral bone in the posterior zeugopod.

respiratory system
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Facet
comment: This class denotes respiratory system

Nervous System
type: Class
subclass of: SIO_010003
definition: The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior

Hair
type: Class
subclass of: SIO_010002
type: NamedIndividual
type: Facet
definition: A filament, mostly protein, that grows from follicles found in the dermis[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Hair]

Esophagus
type: Class
subclass of: SIO_010003
comment: This class denotes Esophagus

urine
type: Class
subclass of: bodily fluid
type: NamedIndividual
type: Facet
definition: Excretion that is the output of a kidney [database_cross_reference: http://en.wikipedia.org/wiki/Urine][database_cross_reference: https://github.com/geneontology/go-ontology/issues/11025]

Tooth
type: Class
subclass of: SIO_010002
type: NamedIndividual
type: Facet
definition: Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food. [database_cross_reference: http://orcid.org/0000-0002-6601-2165][database_cross_reference: http://en.wikipedia.org/wiki/Tooth_(animal)]

cerebrospinal fluid
type: Class
subclass of: SIO_010046
definition: A clear, colorless fluid that is found in the brain and spinal cord.

saliva
type: Class
subclass of: bodily fluid
type: NamedIndividual
type: Facet
definition: A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions. [database_cross_reference: http://en.wikipedia.org/wiki/Saliva][database_cross_reference: GO:0046541]

milk
type: Class
subclass of: bodily fluid
subclass of: mammary gland fluid/secretion
type: NamedIndividual
type: Facet
IAO_0000115: An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation.
comment: This class denotes milk
notation: BR

blood plasma
type: Class
subclass of: bodily fluid
subclass of: EFO_0001941
type: NamedIndividual
type: Facet
definition: The liquid component of blood, in which erythrocytes are suspended. [database_cross_reference: http://orcid.org/0000-0002-6601-2165]

blood serum
type: Class
subclass of: bodily fluid
subclass of: EFO_0001941
definition: Liquid derived from blood plasma that has clotting factors removed. [database_cross_reference: http://en.wikipedia.org/wiki/Serum_(blood)][database_cross_reference: http://orcid.org/0000-0002-6601-2165]
notation: SERUM

placenta
type: Class
subclass of: Biospecimen
subclass of: Pregnancy Sample
subclass of: SIO_010002
type: NamedIndividual
type: Facet
definition: Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. [database_cross_reference: http://en.wikipedia.org/wiki/Placenta][database_cross_reference: http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm]

feces
type: Class
subclass of: Biospecimen
definition: Portion of semisolid bodily waste discharged through the anus[MW, modified] [database_cross_reference: http://en.wikipedia.org/wiki/Feces][database_cross_reference: http://www.merriam-webster.com/dictionary/feces]

Trunk
type: Class
subclass of: SIO_010046
definition: Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present.

spinal cord
type: Class
subclass of: SIO_000004
comment: This class denotes spinal cord

umbilical cord
type: Class
subclass of: SIO_001262
comment: This class denotes umbilical cord

Patella
type: Class
subclass of: SIO_010046
definition: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella.

Femur
type: Class
subclass of: SIO_010046
comment: This class denotes Femur
alternative label: upper leg bone

bodily fluid
type: Class
subclass of: Biospecimen
comment: Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. (Source: UBERON Ontology)

mammary gland fluid/secretion
type: Class
subclass of: Thing
comment: This class denotes mammary gland fluid/secretion

meconium
type: Class
subclass of: feces
subclass of: Pregnancy Sample
type: NamedIndividual
type: Facet
definition: A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth. [database_cross_reference: BTO:0000838]

Sputum
type: Class
subclass of: Biospecimen
definition: Matter ejected from the lungs, bronchi, and trachea, through the mouth. [database_cross_reference: Dorlands_Medical_Dictionary:MerckSource]

Nail
type: Class
subclass of: SIO_010002
type: NamedIndividual
type: Facet
alternative label: nail of manual digit
definition: A nail that is part of a manual digit. [database_cross_reference: OBOL:automatic]

umbilical cord blood
type: Class
subclass of: Whole Blood
subclass of: Pregnancy Sample
type: NamedIndividual
type: Facet
definition: Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. [database_cross_reference: http://en.wikipedia.org/wiki/Cord_blood]

unit
type: Class
subclass of: Thing
comment: This class denotes unit

concentration unit
type: Class
subclass of: Thing
comment: This class denotes concentration unit

mass density unit
type: Class
subclass of: Thing
type: NamedIndividual
type: SIO_000074
comment: "A density unit which is a standard measure of the mass of a substance in a given volume." [UOC:GVG]
notation: mdu

area density unit
type: Class
subclass of: Thing
type: NamedIndividual
type: SIO_000074
comment: "A density unit which is a standard measure of the mass exerting an influence on a given area." [Wikipedia:Wikipedia]
notation: adu

frequency unit
type: Class
subclass of: Thing
comment: "A unit which is a standard measure of the number of repetitive actions in a particular time." [NIST:NIST]

counts per minute
type: Class
subclass of: Thing
type: NamedIndividual
type: SIO_000074
comment: "An activity (of a radionuclide) unit which is equal to the number of light emissions produced by ionizing radiation in one minute." [ORCBS:ORCBS]
notation: cpm

mass percentage
type: Class
type: NamedIndividual
type: SIO_000074
notation: w/w

unit per volume unit
type: Class
subclass of: Thing
comment: "A concentration unit which is a standard measure of the number of units, as an agreed arbitrary amount, of a given substance per a specific volume of solution." [Webmd:Webmd]

cell concentration unit
type: Class
subclass of: Thing
comment: "A concentration unit which denotes the average cell number in a given volume." [Bioedonline:Bioedonline]

rate unit
type: Class
subclass of: Thing
comment: "A unit which represents a standard measurement occurrence of a process per unit time." [UOC:GVG]

milligram per deciliter
type: Class
equivalent class: EFO_0004374
subclass of: mass density unit
type: NamedIndividual
type: SIO_000074
type: NodeShape
comment: This class denotes milligram per deciliter
notation: mg/dl

Microgram per Deciliter
type: Class
subclass of: mass density unit
type: NamedIndividual
type: SIO_000074
type: NodeShape
comment: A mass unit density which is equal to mass of an object in micrograms divided by the volume in deciliters. (Source: Units Ontology)
notation: µg/dl

tributyl phosphate
type: Class
subclass of: Organophosphorus Flame Retardant
type: NamedIndividual
type: NodeShape
comment: A trialkyl phosphate that is the tributyl ester of phosphoric acid. (Source: ChEBI)
notation: TNBP

Autism Spectrum Disorder related condition
type: Class
subclass of: developmental disorder of mental health
type: NamedIndividual
type: Quality Value
definition: Quality refers to children who do not meet DSM criteria for ASD but have scores on ADOS and Mullens that suggest related outcome. All potential options seems to fall under this class from the Autism Ontology
notation: HHEAR_150

2-hydroxyphenanthrene + 3-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
subclass of: Restriction
  on property: SIO_000369
  some values from: 2-hydroxyphenanthrene
subclass of: Restriction
  on property: SIO_000369
  some values from: 3-hydroxyphenanthrene
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-hydroxyphenanthrene + 3-hydroxyphenanthrene
notation: PHEN2PHEN3

Mono-2-ethyl-5-oxohexylterephthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes Mono-2-ethyl-5-oxohexylterephthalate
notation: MEOHTP

Phenanthrene tetrol
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes Phenanthrene tetrol
notation: PHET

microgram per gram
type: Class
subclass of: concentration unit
type: NamedIndividual
type: SIO_000074
notation: ug/g

mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-2-ethyl-5- carboxypentyl terephthalate (DEHTP)
notation: MECPTP

mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-2-ethyl-5-hydroxyhexyl terephthalate (DEHTP)
notation: MEHHTP

monooxoisononyl phthalate (DiNP)
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes monooxoisononyl phthalate (DiNP)
notation: MONP

A Sample has a Pairing
type: Class
subclass of: SIO_001049
was approved by: PER-Jeanette-Stingone
definition: Refers to having paired samples.
editorial note: This actually should be a process. What should we do?

Abnormal hemoglobin variant observed
type: Class
subclass of: SIO_001167
comment: This class denotes Abnormal hemoglobin variant observed

Acculturation
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Acculturation explains the process of cultural change and psychological change that results following meeting between cultures. This metaclass contains all classes that measure this process.

Alcohol, Tobacco, and Illicit Drug Use
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Alcohol, Tobacco, and Illicit Drug Use Indicator Class

Analysis Mode
type: Class
subclass of: Sample Indicator
type: NamedIndividual
type: Quality Variable
definition: Analysis Mode

Analyte
type: Class
subclass of: SIO_010004
comment: This class denotes Analyte

Analyzed at a later date than rest of samples on worksheet (not a repeat)
type: Class
subclass of: SIO_001167
comment: This class denotes Analyzed at a later date than rest of samples on worksheet (not a repeat)

Anthropometry
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Attributes pertaining to the scientific study of the measurements and proportions of the human body.

Atomic Fluorescence Spectroscopy Instrument
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light.

Atomic Spectroscopy
type: Class
subclass of: Spectroscopy
comment: This class denotes Atomic Spectroscopy

Behavior Rating Inventory of Executive Function - Preschool Version
type: Class
subclass of: executive function assessment
definition: Standardized rating scale designed to specifically measure the range of executive function in preschool-aged children

Below LOD, results repeated and confirmed (37, 33)
type: Class
subclass of: SIO_001167
comment: This class denotes Below LOD, results repeated and confirmed (37, 33)

Biological Response
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
definition: Indicator of biological response to environmental exposure
editorial note: abolic_SDD_v1.xlsx

Birth Cohort Study
type: Class
subclass of: cohort study
comment: This class denotes Birth Cohort Study

Birth Outcome
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Birth Outcomes Indicator Class

Blackbody Infrared Radiative Dissociation (BIRD)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Blackbody Infrared Radiative Dissociation (BIRD)

Broken Mitest
type: Class
subclass of: SIO_001167
comment: This class denotes Broken Mitest

Cellular debris present
type: Class
subclass of: SIO_001167
comment: This class denotes Cellular debris present

Childhood Cohort Study
type: Class
subclass of: cohort study
comment: This class denotes Childhood Cohort Study

Chromatography Instrument
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.

Sample Collection
type: Class
subclass of: SIO_000417
subclass of: Activity
subclass of: Restriction
  on property: RO_0004009
  some values from: SIO_001050
was approved by: PER-Jeanette-Stingone
comment: An event in which some sample is collected for measurement or analysis
definition: Collection Date of Sample

College Graduate
type: Class
subclass of: College Graduate or Higher
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: The quality of having graduated from College
notation: HHEAR_12

Collision-Induced Dissociation (CID)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Collision-Induced Dissociation (CID)

Color Object Association Test
type: Class
subclass of: Questionnaire
subclass of: Neurocognitive Assessment
definition: a reliable and a valid measure of declarative memory for healthy children ages 18-36 months, living in a disadvantaged community

Competitive Immunoassay
type: Class
subclass of: Immunoassay
comment: This class denotes Competitive Immunoassay

Conceiving
type: Class
subclass of: Conceiving Activity
subclass of: SIO_000587
comment: to become pregnant with a child.

Cyclomicrons present
type: Class
subclass of: SIO_001167
comment: This class denotes Cyclomicrons present

Delivery Characteristics
type: Class
subclass of: Study Indicator
definition: Attributes related to the delivery of a child.

Demographic
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
was approved by: PER-Jeanette-Stingone
definition: Demographics are quantifiable characteristics of a given population.
editorial note: SDD-2016-1431-P01_SG_Dictionary_SDD_v1.xlsx

Detectable
type: Class
subclass of: SIO_001167
comment: This class denotes Detectable

Developmental Quality
type: Class
subclass of: SIO_000475
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: Refers to which stage of development a person is in.

Diet and Nutrition
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Diet and Nutrition Indicator

Difference
type: Class
subclass of: SIO_000052
definition: Variables derived from taking the difference of two other variables. For example, the first difference of a time series {yt} is defined as Dyt = yt - yt-1

Dilution required
type: Class
subclass of: SIO_001167
comment: This class denotes Dilution required

Direct Mercury Analyzer
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: Direct mercury analysis incorporates the following sequence: thermal decomposition, catalytic conversion, amalgamation, and atomic absorption spectrophotometry. Controlled heating stages are implemented to first dry and then thermally decompose a sample introduced into a quartz tube. A continuous flow of oxygen carries the decomposition products through a hot catalyst bed where halogens, nitrogen, and sulfur oxides are trapped. All mercury species are reduced to Hg(0) and are then carried along with reaction gases to a gold amalgamator where the mercury is selectively trapped. All nonmercury vapors and decomposition products are flushed from the system by the continuous flow of gas. The amalgamator is subsequently heated and releases all trapped mercury to the single-beam, fixed-wavelength atomic absorption spectrophotometer. Absorbance is measured at 253.7 nm as a function of mercury content

Early Childhood Vigilance Test
type: Class
subclass of: Questionnaire
subclass of: Neurocognitive Assessment
definition: a computer-based assessment of sustained attention during which the child is required to watch a screen where various animated stimuli disappear and reappear

Electron Capture Dissociation (ECD)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Electron Capture Dissociation (ECD)

Electron Transfer Dissociation (ETD)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Electron Transfer Dissociation (ETD)

Electron-Detachment Dissociation (EDD)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Electron-Detachment Dissociation (EDD)

Electrospray Ionization Mass Spectrometry
type: Class
subclass of: Mass Spectrometry
was approved by: PER-Jim-McCusker
definition: Mass spectrometry using ESI is called electrospray ionization mass spectrometry (ESI-MS) or, less commonly, electrospray mass spectrometry (ES-MS). ESI is a so-called 'soft ionization' technique, since there is very little fragmentation. This can be advantageous in the sense that the molecular ion (or more accurately a pseudo molecular ion) is always observed, however very little structural information can be gained from the simple mass spectrum obtained. This disadvantage can be overcome by coupling ESI with tandem mass spectrometry (ESI-MS/MS). Another important advantage of ESI is that solution-phase information can be retained into the gas-phase.

Environmental Exposure
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
was approved by: PER-Jeanette-Stingone
definition: EnvironmentalExposure Indicator Class
editorial note: may need to refine this name in order to clearly differentiate from environmental exposures measured within CHEAR. Perhaps ExternalEnvironmental Exposure. Ok for now but we may want to discuss.

Enzyme Immunoassay
type: Class
subclass of: Immunoassay
comment: This class denotes Enzyme Immunoassay

Exposure Monitoring Instrument
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: A physical instrument that monitors the environment for chemical exposures.

Failed negative control
type: Class
subclass of: SIO_001167
comment: This class denotes Failed negative control

Failed positive control
type: Class
subclass of: SIO_001167
comment: This class denotes Failed positive control

Fenton Preterm Growth Chart
type: Class
subclass of: SIO_000442
definition: A growth chart adusted for gestational age

Fibrin present
type: Class
subclass of: SIO_001167
comment: This class denotes Fibrin present

Freeze/Thaw Cycles Count
type: Class
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of Freeze/Thaw cycles.

Gas Chromatography
type: Class
subclass of: Chromatography
comment: This class denotes Gas Chromatography

Gravimetric Analysis Instrument
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle behind this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative quantities of the other constituents are known.

Greater than 99th percentile
type: Class
subclass of: SIO_001167
comment: This class denotes Greater than 99th percentile

HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results
type: Class
subclass of: SIO_001167
comment: This class denotes HUC sample having discrepancy between fluorometer results and semi quantative Albustix test results

Healthcare Access
type: Class
subclass of: Study Indicator
definition: Healthcare Access

Hemolyzed (covers all three levels) and contaminated
type: Class
subclass of: SIO_001167
comment: This class denotes Hemolyzed (covers all three levels) and contaminated

Hemolyzed (covers all three levels) and debris present
type: Class
subclass of: SIO_001167
comment: This class denotes Hemolyzed (covers all three levels) and debris present

Hemolyzed (covers all three levels) and lipemic
type: Class
subclass of: SIO_001167
comment: This class denotes Hemolyzed (covers all three levels) and lipemic

Hemolyzed (covers all three levels), lipemic, and icteric
type: Class
subclass of: SIO_001167
comment: This class denotes Hemolyzed (covers all three levels), lipemic, and icteric

High Performance Liquid Chromatography
type: Class
subclass of: Chromatography
comment: This class denotes High Performance Liquid Chromatography

Housing Characteristic
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Housing Characteristic Indicator Class

Icteric
type: Class
subclass of: SIO_001167
comment: This class denotes Icteric

Inductively Coupled Plasma Mass Spectrometry
type: Class
subclass of: Mass Spectrometry
comment: This class denotes Inductively Coupled Plasma Mass Spectrometry

Infrared Multiphoton Dissociation (IRMPD)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Infrared Multiphoton Dissociation (IRMPD)

Initial concentration higher than the highest standard
type: Class
subclass of: SIO_001167
comment: This class denotes Initial concentration higher than the highest standard

Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)
type: Class
subclass of: SIO_001167
comment: This class denotes Initial concentration higher than the highest standard, insufficient volume for repeat analysis (93, 18)

Interfering substances present
type: Class
subclass of: SIO_001167
comment: This class denotes Interfering substances present

Irregular result, no concentration reported
type: Class
subclass of: SIO_001167
comment: This class denotes Irregular result, no concentration reported

Kaufman ABC
type: Class
subclass of: Neurocognitive Assessment
definition: culturally fair, cognitive ability test for children

Kaufman ABC Sequence Subscale
type: Class
subclass of: Neurocognitive Assessment
definition: Subscale of Kaufman ABC designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas

Lab confirmed result
type: Class
subclass of: SIO_001167
comment: This class denotes Lab confirmed result

Laboratory Result
type: Class
subclass of: Indicator
definition: A measurement taken on a sample.

Lipemic
type: Class
subclass of: SIO_001167
comment: This class denotes Lipemic

Lipemic and turbid
type: Class
subclass of: SIO_001167
comment: This class denotes Lipemic and turbid

Lipemic sample, clarified before running
type: Class
subclass of: SIO_001167
comment: This class denotes Lipemic sample, clarified before running

Liquid Chromotography -tandem mass spectrometry
type: Class
subclass of: Mass Spectrometry
comment: This class denotes Liquid Chromotography -tandem mass spectrometry

Liquid Chromotography-Mass Spectrometery
type: Class
subclass of: Mass Spectrometry
comment: This class denotes Liquid Chromotography-Mass Spectrometery

Liquid Chromotography-Multistage Mass Spectrometery
type: Class
subclass of: Mass Spectrometry
comment: This class denotes Liquid Chromotography-Multistage Mass Spectrometery

Markedly hemolyzed
type: Class
subclass of: SIO_001167
comment: This class denotes Markedly hemolyzed

Mass Spectrometer
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio. In simpler terms, a mass spectrum measures the masses within a sample. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures.

Medical History
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Medical History Indicator Class

Microplate Reader
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: Instruments which are used to detect biological, chemical or physical events of samples in microtiter plates. They are widely used in research, drug discovery, bioassay validation, quality control and manufacturing processes in the pharmaceutical and biotechnological industry and academic organizations. Sample reactions can be assayed in 6-1536 well format microtiter plates. The most common microplate format used in academic research laboratories or clinical diagnostic laboratories is 96-well (8 by 12 matrix) with a typical reaction volume between 100 and 200 µL per well. Higher density microplates (384- or 1536-well microplates) are typically used for screening applications, when throughput (number of samples per day processed) and assay cost per sample become critical parameters, with a typical assay volume between 5 and 50 µL per well. Common detection modes for microplate assays are absorbance, fluorescence intensity, luminescence, time-resolved fluorescence, and fluorescence polarization.

Mitest not capped
type: Class
subclass of: SIO_001167
comment: This class denotes Mitest not capped

Moderately hemolyzed
type: Class
subclass of: SIO_001167
comment: This class denotes Moderately hemolyzed

Neighborhood Characteristic
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Neighborhood Characteristic Indicator Class

No FOL result; FOL = 8 ng/mL assumed
type: Class
subclass of: SIO_001167
comment: This class denotes No FOL result; FOL = 8 ng/mL assumed

No Hct, Hct=40 assumed
type: Class
subclass of: SIO_001167
comment: This class denotes No Hct, Hct=40 assumed

No preservative added
type: Class
subclass of: SIO_001167
comment: This class denotes No preservative added

Not Current Student
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
definition: The state of an individual not currently engaged in educational activity as a pupil.
notation: HHEAR_141

Obvious coarse debris
type: Class
subclass of: SIO_001167
comment: This class denotes Obvious coarse debris

Oral Health
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Oral Health Indicator Class

Overloaded filter
type: Class
subclass of: SIO_001167
comment: This class denotes Overloaded filter

Panel change
type: Class
subclass of: SIO_001167
comment: This class denotes Panel change

Parental Health and Family History
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Parental Health and Family History Indicator Class

Partial match
type: Class
subclass of: SIO_001167
comment: This class denotes Partial match

Personal Product Use
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Personal Product Use Indicator Class

Physical Activity and Fitness
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Physical Activity and Fitness Indicator Class

Physical And Mental Assessment
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Physical and Mental Assessments Indicator Class

Predominantly fibrous material
type: Class
subclass of: SIO_001167
comment: This class denotes Predominantly fibrous material

Pregnancy Characteristic
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Pregnancy Characteristic Indicator Class

Pregnancy Cohort Study
type: Class
subclass of: cohort study
comment: This class denotes Pregnancy Cohort Study

Preschool Child Behavior Checklist
type: Class
subclass of: Neurocognitive Assessment
definition: Child Behavior Checklist for ages 1 ½ through 5

Preschool Child Behavior Checklist Internalizing Subscale
type: Class
subclass of: Neurocognitive Assessment
definition: Subscale of preschool CBCL that assesses internalizing behaviors

Preschool Child Behavior Checklist Externalizing Subscale
type: Class
subclass of: Neurocognitive Assessment
definition: Subscale of preschool CBCL that assesses externalizing behaviors

Prescription Medication and Dietary Supplements
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Prescription Medication and Dietary Supplements are forms of medical treatment.

Quantity of sample insufficient for repeat analysis
type: Class
subclass of: SIO_001167
comment: This class denotes Quantity of sample insufficient for repeat analysis

Red blood cells present
type: Class
subclass of: SIO_001167
comment: This class denotes Red blood cells present

Refractometer
type: Class
subclass of: Physical Instrument
was approved by: PER-Jim-McCusker
definition: A laboratory or field device for the measurement of an index of refraction (refractometry). The index of refraction is calculated from Snell's law while for mixtures, the index of refraction can be calculated from the composition of the material using several mixing rules such as the Gladstone–Dale relation and Lorentz–Lorenz equation.

Replicate Number
type: Class
subclass of: Sample Indicator
definition: Replicate Number

Reproductive Health
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Reproductive Health Indicator Class

Result repeated and confirmed
type: Class
subclass of: SIO_001167
comment: This class denotes Result repeated and confirmed

Result repeated with diluted sample
type: Class
subclass of: SIO_001167
comment: This class denotes Result repeated with diluted sample

Result reported based on fewer replicates than required
type: Class
subclass of: SIO_001167
comment: This class denotes Result reported based on fewer replicates than required

Reverse-Phase Mass Spectrometry Profiling
type: Class
subclass of: Mass Spectrometry
comment: This class denotes Reverse-Phase Mass Spectrometry Profiling

Run out-of-contol; insufficient sample for repeat analysis
type: Class
subclass of: SIO_001167
comment: This class denotes Run out-of-contol; insufficient sample for repeat analysis

Sample frozen
type: Class
subclass of: SIO_001167
comment: This class denotes Sample frozen

Sample integrity/quality compromised preventing analysis
type: Class
subclass of: SIO_001167
comment: This class denotes Sample integrity/quality compromised preventing analysis

Sample older than 2 weeks
type: Class
subclass of: SIO_001167
comment: This class denotes Sample older than 2 weeks

Samples Arrived Thawed and Analyzed
type: Class
subclass of: SIO_001167
comment: This class denotes Samples Arrived Thawed and Analyzed

Screening
type: Class
subclass of: SIO_000417
was approved by: PER-Jeanette-Stingone
definition: The time period during which a screening process is used to determine the inclusion of a subject in a study.

Short sample; sample probe picked up incomplete volume first time
type: Class
subclass of: SIO_001167
comment: This class denotes Short sample; sample probe picked up incomplete volume first time

Sleep Characterisitic
type: Class
subclass of: Study Indicator
was approved by: PER-Jeanette-Stingone
definition: Sleep Characterisitics Indicator Class

Slightly hemolyzed
type: Class
subclass of: SIO_001167
comment: This class denotes Slightly hemolyzed

Small clot present
type: Class
subclass of: SIO_001167
comment: This class denotes Small clot present

Socioeconomic Status
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
was approved by: PER-Jeanette-Stingone
definition: Socioeconomic Status Indicator Class

Specimen analyzed in singlicate for an assay that requires duplicates
type: Class
subclass of: SIO_001167
comment: This class denotes Specimen analyzed in singlicate for an assay that requires duplicates

Specimen analyzed with less than normal quantity
type: Class
subclass of: SIO_001167
comment: This class denotes Specimen analyzed with less than normal quantity

Specimen analyzed with less than usual dilution
type: Class
subclass of: SIO_001167
comment: This class denotes Specimen analyzed with less than usual dilution

Study Baseline
type: Class
subclass of: Study Activity
definition: Point in study set to initial point.

Surface-Induced Dissociation (SID)
type: Class
subclass of: Tandem Mass Spectrometry
comment: This class denotes Surface-Induced Dissociation (SID)

Torn bag (Mitest intact, capped)
type: Class
subclass of: SIO_001167
comment: This class denotes Torn bag (Mitest intact, capped)

Torn, perforated screen
type: Class
subclass of: SIO_001167
comment: This class denotes Torn, perforated screen

Turbid
type: Class
subclass of: SIO_001167
comment: This class denotes Turbid

Unusual color
type: Class
subclass of: SIO_001167
comment: This class denotes Unusual color

Unusually high
type: Class
subclass of: SIO_001167
comment: This class denotes Unusually high

Urine grossly hematuric
type: Class
subclass of: SIO_001167
comment: This class denotes Urine grossly hematuric

Valid measurement, results repeated and confirmed (0, 33)
type: Class
subclass of: SIO_001167
comment: This class denotes Valid measurement, results repeated and confirmed (0, 33)

Value above LOD but below LLOQ
type: Class
subclass of: SIO_001167
comment: This class denotes Value above LOD but below LLOQ

Value below LLOQ, no LOD provided
type: Class
subclass of: SIO_001167
comment: This class denotes Value below LLOQ, no LOD provided

Value greater than ULOQ
type: Class
subclass of: SIO_001167
comment: This class denotes Value greater than ULOQ

Value less than LOD
type: Class
subclass of: SIO_001167
comment: This class denotes Value less than LOD

Very turbid
type: Class
subclass of: SIO_001167
comment: This class denotes Very turbid

Visit
type: Class
subclass of: SIO_000417
definition: The time interval of an encounter between a study subject and a study administrator.

did not precipitate
type: Class
subclass of: SIO_001167
comment: This class denotes did not precipitate

enzyme-linked immunosorbent assay (ELISA)
type: Class
subclass of: Immunoassay
definition: ELISA is an immunoassay that uses antibodies and color change to identify a substance (Wikipedia)

eosinophils per high-power field
type: Class
subclass of: SIO_000794
comment: A histological count of the eosinophils in a high-power microscopic field of view, or 0.158 mm^2 (x400).

quantity of sample insufficient for analysis
type: Class
subclass of: SIO_001167
comment: This class denotes quantity of sample insufficient for analysis

thawed and clotted
type: Class
subclass of: SIO_001167
comment: This class denotes thawed and clotted

thawed and hemolyzed (covers all three levels)
type: Class
subclass of: SIO_001167
comment: This class denotes thawed and hemolyzed (covers all three levels)

thawed, hemolyzed (covers all three levels) and exposed to light
type: Class
subclass of: SIO_001167
comment: This class denotes thawed, hemolyzed (covers all three levels) and exposed to light

valid measurement
type: Class
subclass of: Measurement
subclass of: SIO_001167
type: NamedIndividual
type: Quality Value
comment: This class denotes valid measurement
notation: HHEAR_351

Absorbance Reader
type: Class
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker
definition: Absorbance readers are used for assays such as ELISA assays, protein and nucleic acid quantification or enzyme activity assays. A light source illuminates the sample using a specific wavelength (selected by an optical filter, or a monochromator), and a light detector located on the other side of the well measures how much of the initial (100%) light is transmitted through the sample: the amount of transmitted light will typically be related to the concentration of the molecule of interest.

Alcohol Use
type: Class
subclass of: Consumption Behavior
type: NamedIndividual
type: Quality Value
definition: Uses Alcohol
notation: HHEAR_83

Assisted Reproductive Therapy
type: Class
subclass of: Pregnancy Characteristic
type: NamedIndividual
type: Quality Value
comment: This class denotes Assisted Reproductive Therapy
notation: HHEAR_7

Atomic Absorption Spectroscopy
type: Class
subclass of: Atomic Spectroscopy
comment: This class denotes Atomic Absorption Spectroscopy

Atomic Emission Spectroscopy
type: Class
subclass of: Atomic Spectroscopy
comment: This class denotes Atomic Emission Spectroscopy

Before
type: Class
subclass of: Relative Time
definition: A negative index of a time measurement in relation to a reference event. A conventional time measurement can be generated from a before time measurement by duplicating the measurement, reversing the sign of the value, and removing the "Before" class.

Biospecimen
type: Class
subclass of: SIO_010412
definition: A biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are stored, ideally they remain equivalent to freshly-collected specimens for the purposes of research.

Cold Vapor Atomic Fluorescence Spectroscopy Instrument
type: Class
subclass of: Atomic Fluorescence Spectroscopy Instrument
was approved by: PER-Jim-McCusker
definition: Used in the measurement of trace amounts of volatile heavy metals such as mercury, cold vapour AFS makes use of the unique characteristic of mercury that allows vapour measurement at room temperature.

Colorimetric Assay
type: Class
subclass of: SIO_001007
comment: This class denotes Colorimetric Assay

Common Era
type: Class
equivalent class: Restriction
  on property: inRelationTo
  has value: CE 1
subclass of: Relative Time
definition: Common era time measurements are referenced against (in relation to) the beginning of the common era, 1 CE (or 1 AD).

Competitive-inhibition enzyme-linked immunosorbent assay
type: Class
subclass of: enzyme-linked immunosorbent assay (ELISA)
comment: This class denotes Competitive-inhibition enzyme-linked immunosorbent assay

Dental Fillings
type: Class
subclass of: Oral Health
type: NamedIndividual
type: Quality Value
comment: This class denotes Dental Fillings
notation: HHEAR_13

Drug History
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
type: NamedIndividual
type: Quality Variable
comment: This class denotes Drug History
notation: HHEAR_14

Fibrinogen Assay (Clauss method)
type: Class
subclass of: SIO_001007
comment: This class denotes Fibrinogen Assay (Clauss method)

Gas Chromatography Instrument
type: Class
subclass of: Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: Gas chromatography (GC) is a common type of chromatography used in analytical chemistry for separating and analyzing compounds that can be vaporized without decomposition. Typical uses of GC include testing the purity of a particular substance, or separating the different components of a mixture (the relative amounts of such components can also be determined). In some situations, GC may help in identifying a compound. In preparative chromatography, GC can be used to prepare pure compounds from a mixture.

Gel Electrophoresis
type: Class
subclass of: SIO_001007
definition: Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.

Haircare Product Use
type: Class
subclass of: Personal Product Use
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
comment: This class denotes Haircare Product Use
notation: HHEAR_30

Hospital Utilization
type: Class
subclass of: Healthcare Access
was approved by: PER-Jeanette-Stingone
definition: Hospital Utilization

Hydrogen–Deuterium Exchange Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Hydrogen–deuterium exchange mass spectrometry can determine the overall deuterium content of molecules which have undergone H/D exchange. Because of the sample preparation required, it is typically considered to provide an accurate measurement of non-exchangeable hydrogen atoms only.

Immunoturbidimetry
type: Class
subclass of: SIO_001007
was approved by: PER-Jim-McCusker
definition: An analytical technique that uses light scattering, a physical phenomenon resulting from the interaction of light with particles in solution, to measure the concentration of particles. The photometric signal is generated by a decrease in light intensity as a direct consequence of increasing turbidity in the reaction well. Immunoturbidimetry uses the classical antigen-antibody reaction. The antigen-antibody complexes are particles which can be optically detected by an photometer.

Inductively Coupled Plasma Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: A type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 10^15 (part per quadrillion, ppq) on non-interfered low-background isotopes. This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.

Known Food Allergies
type: Class
subclass of: Health Outcome
type: NamedIndividual
type: Quality Variable
comment: This class denotes Known Food Allergies

Liquid Chromatography Instrument
type: Class
subclass of: Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: A separation technique in which the mobile phase is a liquid. It can be carried out either in a column or a plane. Present day liquid chromatography that generally utilizes very small packing particles and a relatively high pressure is referred to as high performance liquid chromatography (HPLC).

Mental Health
type: Class
subclass of: Physical And Mental Assessment
was approved by: PER-Jeanette-Stingone
definition: Mental Health Indicator

Methylation Assay
type: Class
subclass of: SIO_001007
definition: An assay that measures the methylation levels of sections of a genome.

MicroPEM
type: Class
subclass of: Exposure Monitoring Instrument
was approved by: PER-Jim-McCusker
definition: The MicroPEM device monitors individual exposures to very fine airborne particles—or particulate matter—at two sizes. PM10 has a diameter of less than 10 micrometers (PM10), which is approximately 1/30th the size of a human hair, and PM2.5, which at diameters of less than 2.5 micrometers, is even smaller.

Microarray Assay
type: Class
subclass of: SIO_001007
definition: An assay that uses a microarray to perform measurements.

Neurocognitive Assessment
type: Class
subclass of: Research or Clinical Assessment Tool
comment: This class denotes Neurocognitive Assessment

No Anti Malarial Use
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Antimalarial Use
type: NamedIndividual
type: Quality Value
comment: This class denotes No Anti Malarial Use
notation: HHEAR_140

Nucleic Acid Sequencing
type: Class
subclass of: SIO_001007
comment: This class denotes Nucleic Acid Sequencing

Perfume Use
type: Class
subclass of: Personal Product Use
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
comment: This class denotes Perfume Use
notation: HHEAR_74

Polymerase Chain Reaction
type: Class
subclass of: SIO_001007
comment: This class denotes Polymerase Chain Reaction

Pregnancy Complication
type: Class
subclass of: Pregnancy Characteristic
type: NamedIndividual
type: Quality Value
comment: This class denotes Pregnancy Complication
notation: HHEAR_75

Preterm Birth
type: Class
equivalent class: Class
  complement of: Term Birth
subclass of: Birth Outcome By Gestational Age
disjoint with: Term Birth
type: NamedIndividual
type: Quality Value
was approved by: PER-Jim-McCusker
definition: Preterm birth, also known as premature birth, is the birth of a baby at fewer than 37 weeks gestational age.
notation: HHEAR_88

Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry
type: Class
subclass of: Liquid Chromotography-Mass Spectrometery
comment: This class denotes Quadrapole Time-of-Flight Liquid Chromotography-Mass Spectrometry

Reichert AR200 Handheld Digital Refractometer
type: Class
subclass of: Refractometer
was approved by: PER-Jim-McCusker
definition: Lightweight digital refractometer designed for the food, beverage, agricultural, industrial-fluid, chemical, petrochemical, pharmaceutical, medical, and plastic industries.

Religion
type: Class
subclass of: Demographic
type: NamedIndividual
type: Quality Variable
definition: Religious Belief

Route Of Delivery
type: Class
subclass of: Delivery Characteristics
type: NamedIndividual
type: Quality Variable
comment: This class denotes Route Of Delivery

Sandwich ELISA
type: Class
subclass of: enzyme-linked immunosorbent assay (ELISA)
definition: Sandwich ELISAs involve attachment of a capture antibody to a solid phase support. Samples containing known or unknown antigen are then added in a matrix or buffer that will minimize attachment to the solid phase. An enzyme-labeled antibody is then added for detection.

Shotgun Lipidomics
type: Class
subclass of: Electrospray Ionization Mass Spectrometry
comment: This class denotes Shotgun Lipidomics

SpectraMax Plus 384 Microplate Reader
type: Class
subclass of: Microplate Reader
was approved by: PER-Jim-McCusker
definition: Get absorbance measurements from 190 to 1000 nm quickly for samples in test tubes, cuvettes, and 96- or 384-well microplates. The SpectraMax® Plus 384 Microplate Reader gives you walk-up convenience for both standard spectrophotometer and microplate reader applications on the same instrument. Monochromator wavelength selection saves you the time and trouble of ever having to change out filters. Typical applications for this powerful reader include DNA and RNA quantification, enzyme kinetic assays, and ELISA based assays. When your project is ready for high throughput, take advantage of StakMax® automated microplate handling compatibility for full robotic integration.

Subject
type: Class
subclass of: SIO_000016
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Study
was approved by: PER-Jeanette-Stingone
definition: A living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information

Tandem Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Tandem mass spectrometry, also known as MS/MS or MS2, involves multiple steps of mass spectrometry selection, with some form of fragmentation occurring in between the stages. In a tandem mass spectrometer, ions are formed in the ion source and separated by mass-to-charge ratio in the first stage of mass spectrometry (MS1). Ions of a particular mass-to-charge ratio (precursor ions) are selected and fragment ions (product ions) are created by collision-induced dissociation, ion-molecule reaction, photodissociation, or other process. The resulting ions are then separated and detected in a second stage of mass spectrometry (MS2).

Term Birth
type: Class
subclass of: Birth Outcome By Gestational Age
type: NamedIndividual
type: Quality Value
comment: This class denotes Term Birth
notation: HHEAR_97

Tobacco Smoke Exposure
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: Quality Value
type: Facet
comment: This class denotes Tobacco Smoke Exposure
notation: HHEAR_98

Tri-Cell DMA-80 Direct Mercury Analyzer
type: Class
subclass of: Direct Mercury Analyzer
was approved by: PER-Jim-McCusker
definition: The DMA-80 is based on the principles of sample thermal decomposition, mercury amalgamation and atomic absorption detection. The DMA-80 has been used to develop the US EPA method 7473 (Mercury in solids and solutions by thermal decomposition, amalgamation, and atomic absorption spectrophotometry). It is furthermore compliant with ASTM method D-6722-01 (Total mercury in coal and coal combustion residues) and ASTM method D-7623-10 (Total mercury in crude oil).

Used Only Anti Malarials or No Medications
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Drug Other Than Antimalarial Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Used Only Anti Malarials or No Medications
notation: HHEAR_139

Biomolecule
type: Class
subclass of: Biospecimen
definition: A biospecimen that is composed of molecular entities.

Bisulfite Pyrosequencing
type: Class
subclass of: Nucleic Acid Sequencing
comment: This class denotes Bisulfite Pyrosequencing

Body Weight Quality
type: Class
subclass of: Anthropometry
subclass of: SIO_000005
definition: A categorization of body mass relative to the height, as defined using Body Mass Index.

Car Count
type: Class
subclass of: Housing Characteristic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
definition: Total Number of Cars in the Home
editorial note: Again, this isn't related to physical properties of housing. This is more closely related to Socioeconomic Status. Consider moving it.

Consumed Alcohol
type: Class
subclass of: Alcohol Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Consumed Alcohol
notation: HHEAR_52

Date of Birth
type: Class
subclass of: Demographic
subclass of: SIO_000417
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Date of day on which a person was born.

Did Not Consume Alcohol
type: Class
subclass of: Alcohol Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Did Not Consume Alcohol
notation: HHEAR_53

Diet Quantity
type: Class
subclass of: Diet and Nutrition
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: A quantity relating to diet and nutrition.
editorial note: What differentiated diet from nutrition? That is why is this needed since we have the DietAndNutrition Class

Floor Covering By Type
type: Class
subclass of: Q47011175
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: Type of material that makes up the floor.

Gravida
type: Class
subclass of: Pregnancy Characteristic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Pregnancy Count, regardless of whether pregnancy was carried to Term.

High-Performance Liquid Chromatography
type: Class
subclass of: Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: High-performance liquid chromatography (HPLC; formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.

Household Appliance Count
type: Class
subclass of: Housing Characteristic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Total number of appliances that can be found in the home.

In Vitro Fertilization
type: Class
subclass of: Assisted Reproductive Therapy
type: NamedIndividual
type: Quality Value
comment: This class denotes In Vitro Fertilization
notation: HHEAR_50

Insurance
type: Class
subclass of: Healthcare Access
subclass of: Socioeconomic Status
type: NamedIndividual
type: Quality Value
type: Quality Variable
type: Facet
comment: This class denotes Insurance
notation: HHEAR_683

Intelligence Quotient
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: A measure of intelligence

Landfill Proximity
type: Class
subclass of: built environment
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: How close a household is to a landfill.

Light Bulb Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Total Number of Lightbulbs in the Home

Limit of Detection
type: Class
subclass of: SIO_001088
definition: The lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blank, the standard deviation of the blank and some confidence factor. Another consideration that affects the detection limit is the accuracy of the model used to predict concentration from the raw analytical signal.

Long Range Polymerase Chain Reaction
type: Class
subclass of: Polymerase Chain Reaction
was approved by: PER-Jim-McCusker
definition: Amplification of DNA lengths that cannot typically be amplified using routine PCR methods or reagents. For simple DNA templates, polymerases optimized for Long Range PCR can amplify up to 30 kb and beyond. For complex, genomic templates, 20 kb is a typical target.

Marital Status
type: Class
subclass of: SIO_000287
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: A person's current conjugal status.

Medical Therapy Procedure
type: Class
subclass of: SIO_001024
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: Medical Therapy Procedure to aide in treatment.

Multiplex real-time PCR
type: Class
subclass of: Polymerase Chain Reaction
comment: This class denotes Multiplex real-time PCR

Non-Spontaneous Preterm Birth
type: Class
equivalent class: Class
  intersection of: Preterm Birth
  intersection of: Non-spontaneous Birth
subclass of: Preterm Birth
subclass of: Non-spontaneous Birth
subclass of: Class
  intersection of: Preterm Birth
  intersection of: Non-spontaneous Birth
type: NamedIndividual
type: Quality Value
comment: This class denotes Non-Spontaneous Preterm Birth
notation: HHEAR_60

Other GI Disease
type: Class
subclass of: Health Outcome
subclass of: SIO_010299
type: NamedIndividual
type: Quality Value
comment: This class denotes Other GI Disease
editorial note: This is a temp concept that needs addressing
notation: HHEAR_69

Pregnancy Sample
type: Class
subclass of: Biospecimen
definition: A sample that is taken at or near pregnancy or birth.

RNA Sequencing
type: Class
subclass of: Nucleic Acid Sequencing
comment: This class denotes RNA Sequencing

Room Count
type: Class
subclass of: Housing Characteristic
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Total Number of Rooms in the Home

SYNAPT G2-Si Mass Spectrometer
type: Class
subclass of: Hydrogen–Deuterium Exchange Mass Spectrometer
was approved by: PER-Jim-McCusker
comment: This class denotes SYNAPT G2-Si Mass Spectrometer

Socioeconomic Status Index
type: Class
subclass of: Socioeconomic Status
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
definition: A measure of SES.
editorial note: This is a specific index, derived from other variables. So, it should somehow be connected to this variables. Also, we may want to be more specific about the type of index that it is. Perhaps there should be a general SESIndex and then subclasses of specific measures?

Solid-Phase Sandwich ELISA
type: Class
subclass of: Sandwich ELISA
was approved by: PER-Jim-McCusker
comment: This class denotes Solid-Phase Sandwich ELISA

Spontaneous Preterm Birth
type: Class
equivalent class: Class
  intersection of: Spontaneous Labor and Birth
  intersection of: Preterm Birth
subclass of: Spontaneous Labor and Birth
subclass of: Preterm Birth
subclass of: Class
  intersection of: Spontaneous Labor and Birth
  intersection of: Preterm Birth
type: NamedIndividual
type: Quality Value
comment: This class denotes Spontaneous Preterm Birth
notation: HHEAR_91

Targeted Analyte
type: Class
subclass of: Study Indicator
subclass of: Analyte
type: NamedIndividual
type: Facet Category
was approved by: PER-Jeanette-Stingone
definition: A targeted analyte is one that has been selected by the CHEAR program as a prioritized analyte for CHEAR lab hubs to measure and has been carried over to HHEAR.

Targeted Sequencing
type: Class
subclass of: Nucleic Acid Sequencing
definition: Nucleic acid sequencing that limits the scope of sequencing by filtering out portions of the nucleic acids that do not meet some criteria.

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
type: Class
subclass of: Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: A tandem mass spectrometer consisting of two quadrupole mass analyzers in series, with a (non-mass-resolving) radio frequency (RF)–only quadrupole between them to act as a cell for collision-induced dissociation.

active eosinophilic esophagitis
type: Class
equivalent class: Restriction
  on property: SIO_001280
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: SIO_000008
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of more than 25 eosinophils per high-power field area, or 0.158 mm^2 (400x).

eosinophilic esophagitis in remission
type: Class
equivalent class: Restriction
  on property: SIO_001280
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: SIO_000008
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is active when a biopsy of the esophagus reveals a count of less than 15 eosinophils per high-power field area, or 0.158 mm^2 (400x).

mild eosinophilic esophagitis
type: Class
equivalent class: Restriction
  on property: SIO_001280
  all values from: Class
    intersection of: Esophagus
    intersection of: Restriction
      on property: SIO_000008
      some values from: Class
        intersection of: eosinophils per high-power field
        intersection of: Restriction
subclass of: eosinophilic esophagitis
comment: Eosinophilic esophagitis is mild when a biopsy of the esophagus reveals a count of 15-25 eosinophils per high-power field area, or 0.158 mm^2 (400x).

Active Smoker
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
definition: The quality of actively smoking.
editorial note: How is this different from "smoker'?
notation: HHEAR_2

Adult
type: Class
subclass of: Life Stage
subclass of: Demographic
subclass of: Developmental Quality
subclass of: Study Population
type: NamedIndividual
type: Quality Value
type: Facet
was approved by: PER-Jeanette-Stingone
definition: Refers to a person above a threshold age.
notation: HHEAR_3

Agilent 1100 HPLC
type: Class
subclass of: High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker
comment: This class denotes Agilent 1100 HPLC

Aligent 8800 Triple Quadrupole ICP-MS
type: Class
subclass of: Triple Quadrupole Inductively Coupled Plasma Mass Spectrometer
was approved by: PER-Jim-McCusker
comment: This class denotes Aligent 8800 Triple Quadrupole ICP-MS

Dialkyl Phosphate Pesticide Metabolite
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Dialkyl Phosphate Pesticide Metabolite
notation: UPEST

Apgar Score
type: Class
subclass of: Birth Outcome
subclass of: SIO_001112
subclass of: Restriction
  on property: SIO_000300
  all values from: Datatype
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        min inclusive: 0
    intersection of: Datatype
      on datatype: integer
      with restrictions:
        max inclusive: 10
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: A method to quickly summarize the health of newborn children. The Apgar score was invented by Virginia Apgar in 1952 when Apgar was an anesthesiologist who developed the score in order to ascertain the effects of obstetric anesthesia on babies. The Apgar scale is determined by evaluating the newborn baby on five simple criteria on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10. The five criteria are summarized using words chosen to form a backronym (Appearance, Pulse, Grimace, Activity, Respiration).

Arsenic Species
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
definition: A molecular entity with arsenic components.
notation: UAS

Bathroom Count
type: Class
subclass of: Room Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Total Number of Bathrooms in the Home

Bedroom Count
type: Class
subclass of: Room Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Total Number of Bedrooms in the Home

Boiler Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: A boiler is an object that heats up water. This attribute quantifies the number of boilers in the home.

Buccal Cell
type: Class
subclass of: Cell
definition: Cells collected from the inner epithelium of the cheek

Caesarian Section
type: Class
subclass of: Pregnancy Characteristic
subclass of: Route Of Delivery
type: NamedIndividual
type: Quality Value
definition: Caesarian Section Medical Procedure. One-third of pregnancies in the US end in C-Sections.
notation: HHEAR_20

Canned Food Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats Canned Food
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Frequency of Canned Food Consumption.
editorial note: Also want to list this under Environmental Exposures (b/c canned food has chemicals in the lining so sometimes it is used as a proxy)

Cement Floor
type: Class
subclass of: Floor Covering By Type
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Cement Floor Type
notation: HHEAR_10

Personal Computer Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: The number of personal computers in a household or possessed by a subject

DVD Player Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of devices in the home that play DVDs.

Diet Treatment Medical Therapy
type: Class
subclass of: Medical Therapy Procedure
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Diet Treatment is a form of Medical Therapy.
notation: HHEAR_26

Element
type: Class
subclass of: Targeted Analyte
comment: This class denotes Element

Ever Smoked
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: The quality of having smoking in the past.
notation: HHEAR_136

Fast Food Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats Fast Food
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Frequency of Fast Food Consumption.

Fresh Vegetable Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats Fresh Vegetables
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Frequency of Fresh Vegetable Consumption.

Gas Chromatographer–Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
subclass of: Gas Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: Gas chromatography–mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples, including that of material samples obtained from planet Mars during probe missions as early as the 1970s. GC-MS can also be used in airport security to detect substances in luggage or on human beings. Additionally, it can identify trace elements in materials that were previously thought to have disintegrated beyond identification. Like liquid chromatography–mass spectrometry, it allows analysis and detection even of tiny amounts of a substance.

HPLC with Fluorescence Level Detector
type: Class
subclass of: High-Performance Liquid Chromatography
definition: HPLC paired with a Fluorescence Level Detector. Fluorescence spectroscopy (also known as fluorometry or spectrofluorometry) is a type of electromagnetic spectroscopy that analyzes fluorescence from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light; typically, but not necessarily, visible light. A complementary technique is absorption spectroscopy. In the special case of single molecule fluorescence spectroscopy, intensity fluctuations from the emitted light are measured from either single fluorophores, or pairs of fluorophores.

Health Maintenance Organization Insurance
type: Class
subclass of: Insurance
type: NamedIndividual
type: Quality Value
comment: This class denotes Health Maintenance Organization Insurance
notation: HHEAR_49

Number of Hospital Admissions
type: Class
subclass of: Hospital Utilization
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Hospital Admission By Duration
definition: The number of episodes when a patient is admitted to a hospital; typically measured within a specified time interval.

Infinium Methylation EPIC BeadChip Assay
type: Class
subclass of: Methylation Assay
subclass of: Microarray Assay
comment: This class denotes Infinium Methylation EPIC BeadChip Assay

Insurance Type
type: Class
subclass of: Insurance
type: NamedIndividual
type: Quality Variable
definition: Insurance Type

Liquid Chromatography–Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
subclass of: Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
definition: An analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin.

Macromolecule
type: Class
subclass of: Biomolecule
definition: A very large molecule, such as protein, commonly created by polymerization of smaller subunits (monomers). They are typically composed of thousands of atoms or more. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, carbohydrates and polyphenols) and large non-polymeric molecules (such as lipids and macrocycles).

Malarial Retinopathy
type: Class
subclass of: Retinopathy
type: NamedIndividual
type: Quality Value
definition: Retinopathy due to malaria.
notation: HHEAR_130

Mercury Species
type: Class
subclass of: Targeted Analyte
comment: This class denotes Mercury Species

Microwave Oven Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of machines in the home used to heat up food using microwaves.
editorial note: Putting a note here, but it applies to all of the appliances. These are used to calculate the SES Index that was reported within one of the pilots. So, there needs to be some connection between these terms.

Neighbor
type: Class
subclass of: SIO_000016
subclass of: SIO_000287
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
type: NamedIndividual
type: Quality Value
definition: A person living near or next door to another person.
notation: HHEAR_355

Non-Hispanic Ethnicity
type: Class
subclass of: SIO_001014
type: NamedIndividual
type: Quality Value
type: Facet Value
was approved by: PER-Jeanette-Stingone
definition: Non-Hispanic Ethnicity
notation: HHEAR_58

Non-smoker
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
definition: Doesn't smoke cigarettes.
notation: HHEAR_59

Other Material Finish
type: Class
subclass of: Floor Covering By Type
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Flooring is made from another unspecified material.
notation: HHEAR_70

Perfluoroakyl and Polyfluoroalkyl Substance
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Perfluoroakyl and Polyfluoroalkyl Substance
notation: SPFAS

Parous
type: Class
subclass of: Parity
type: NamedIndividual
type: Quality Value
comment: The state of having produced live offspring
notation: HHEAR_73

Peripheral Blood Mononuclear Cell
type: Class
subclass of: Cell
definition: Any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei.

Previous Smoker
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
definition: The quality of having smoked in the past.
notation: HHEAR_78

Private Insurance or Self Pay
type: Class
subclass of: Insurance
type: NamedIndividual
type: Quality Value
comment: This class denotes Private Insurance or Self Pay
notation: HHEAR_51

Proton Pump Inhibitor Treatment
type: Class
subclass of: Pharmacotherapy
subclass of: proton pump inhibitor agent therapy
subclass of: Restriction
  on property: SIO_000139
  some values from: EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor
type: NamedIndividual
type: Quality Value
definition: Proton Pump Inhibitor Treatment as a form of medical therapy.
editorial note: UPDATE: Yes, add the prescription medication, either as an indicator or as a class under Medical Therapy. Whichever works for the ontology. Why isn't this listed under prescription medication? How do you differentiate between medical therapy and prescription medication?
notation: HHEAR_27

Public Insurance
type: Class
subclass of: Public or No Insurance
type: NamedIndividual
type: Quality Value
comment: This class denotes Public Insurance
notation: HHEAR_79

Relative
type: Class
subclass of: SIO_000016
subclass of: SIO_000287
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Relative
was approved by: PER-Jeanette-Stingone
definition: Broadly, kinship patterns may be considered to include people related by both descent – i.e. social relations during development – and by marriage. Human kinship relations through marriage are commonly called "affinity" in contrast to the relationships that arise in one's group of origin, which may be called one's descent group. In some cultures, kinship relationships may be considered to extend out to people an individual has economic or political relationships with, or other forms of social connections. Within a culture, some descent groups may be considered to lead back to gods or animal ancestors (totems). This may be conceived of on a more or less literal basis.

Severe Malarial Anemia
type: Class
subclass of: Anemia
type: NamedIndividual
type: Quality Value
definition: In holoendemic transmission areas, Severe Malarial Anemia (SMA) is the primary clinical manifestation of severe childhood malaria, with cerebral malaria occurring only in rare cases. Mortality rates from SMA can exceed 30% in pediatric populations residing in holoendemic transmission areas. The pathophysiological processes that contribute to SMA involve direct and indirect destruction of parasitized and non-parasitized red blood cells (RBCs), inefficient and/or suppression of erythropoiesis, and dyserythropoiesis.
notation: HHEAR_127

Small Molecule
type: Class
subclass of: Biomolecule
definition: A small molecule is a low molecular weight (< 900 daltons) organic compound that may help regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.

Smoker
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
definition: The quality of smoking cigarettes.
notation: HHEAR_105

Soil Floor
type: Class
subclass of: Floor Covering By Type
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: The flooring is made of soil.
notation: HHEAR_84

Uses Steroid Treatment
type: Class
subclass of: Pharmacotherapy
subclass of: Restriction
  on property: SIO_000139
  some values from: CHEBI_35341
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Had a form of treatment which uses steroids.
notation: HHEAR_28

Stress Frequency
type: Class
subclass of: Mental Health
subclass of: SIO_000475
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: How frequently a person gets stressed.
editorial note: Again, we might want to link this to a specific assessment?

Toaster Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of appliances used to toast bread.

Tobacco Metabolite
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
comment: This class denotes Tobacco Metabolite
notation: USMOKE

Ultra High Performance Liquid Chromatography Instrument
type: Class
subclass of: High-Performance Liquid Chromatography
was approved by: PER-Jim-McCusker
definition: Modern HPLC systems have been improved to work at much higher pressures, and therefore are able to use much smaller particle sizes in the columns (<2 μm). These "Ultra High Performance Liquid Chromatography" systems or UHPLCs can work at up to 120 MPa (17, 405 lbf/in^2), or about 1200 atmospheres.

Unknown Race
type: Class
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
definition: Unknown Race
notation: HHEAR_48

Unmarried
type: Class
subclass of: Marital Status
type: NamedIndividual
type: Quality Value
definition: Indicates a person not currently joined in a legally binding matrimonial union.
notation: HHEAR_46

VCR Player Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of devices that play VCRs in the home.

Vacuum Cleaner Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of appliances in home used for cleaning rugs.

Washing Machine Count
type: Class
subclass of: Household Appliance Count
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Number of machines used for washing clothes in the home.

Weight for Height Z-Score
type: Class
subclass of: Z-Score
subclass of: SIO_001245
type: NamedIndividual
type: Quantity Variable
definition: Z-Score of the weight/height ratio at a given age.

2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 3, 3', 4, 4', 5, 5', 6, 6'-Decabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE209

2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 3, 4, 4', 5', 6-Heptabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE183

2, 2', 3, 4, 4'-Pentabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 3, 4, 4'-Pentabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE85

2, 2', 4'-Tribromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4'-Tribromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE17

2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4', 5, 5'-Hexabromobiphenyl
editorial note: To Do: align with CHEBI.
notation: PBB153

2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4', 5, 5'-Hexabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE153

2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4', 5, 6'-Hexabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE154

2, 2', 4, 4', 5-Pentabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4', 5-Pentabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE99

2, 2', 4, 4', 6-Pentabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4', 6-Pentabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE100

2, 2', 4, 4'-Tetrabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 2', 4, 4'-Tetrabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE47

2, 3', 4, 4'-Tetrabromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 3', 4, 4'-Tetrabromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE66

2, 4, 4'-Tribromodiphenyl ether
type: Class
subclass of: Polybrominated Diphenyl Ether
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 4, 4'-Tribromodiphenyl ether
editorial note: To Do: align with CHEBI.
notation: BDE28

2, 4, 5, 6-Tetrachlorophenol
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: PHYSICAL DESCRIPTION: Brown flakes or beige solid. Strong odor. (NTP, 1992)
notation: TeCP2456

2-Aminothiazoline-4-carboxylic acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-Aminothiazoline-4-carboxylic acid
editorial note: To Do: align with CHEBI.
notation: ATCA

2-Methylhippuric acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-Methylhippuric acid
editorial note: To Do: align with CHEBI.
notation: MHA2

2-Methylhippuric acid (ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes 2-Methylhippuric acid (ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOC2MH

2-Thioxothiazolidine-4-carboxylic acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-Thioxothiazolidine-4-carboxylic acid
editorial note: To Do: align with CHEBI.
notation: TTCA

2-amnothiazolne-4-carbxylic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes 2-amnothiazolne-4-carbxylic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCATC

2-thoxothazlidne-4-carbxylic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes 2-thoxothazlidne-4-carbxylic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCTTC

3, 5, 6-trichloro-2-pyridinol
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
comment: This class denotes 3, 5, 6-trichloro-2-pyridinol
editorial note: To Do: align with CHEBI.
notation: TCP

3-Methylhippuric acid + 4-Methylhippuric acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-Methylhippuric acid + 4-Methylhippuric acid
editorial note: To Do: align with CHEBI.
notation: MHA34

3-methipurc acd, 4-methipurc acd(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes 3-methipurc acd, 4-methipurc acd(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOC34M

3-phenoxybenzoic acid 2
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-phenoxybenzoic acid
editorial note: To Do: align with CHEBI.
notation: PBA

4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes 4-(methlynitrosamino)-1-(3-pyridyl)-1-butanol
editorial note: To Do: align with CHEBI.
notation: NNAL

Active Non-Tobacco Smoker
type: Class
subclass of: Active Smoker
type: NamedIndividual
type: Quality Value
definition: Active Non-Tobacco Smoker
notation: HHEAR_1

Adolescent Period
type: Class
subclass of: Adolescence
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000582
definition: The age span ranging from adolescence to adulthood

Advanced Graduate Degree
type: Class
subclass of: College Graduate or Higher
type: NamedIndividual
type: Quality Value
definition: Having earned a pos-baccalaureate degree
notation: HHEAR_4

Benzophenone-3
type: Class
subclass of: phenols
type: NamedIndividual
type: Facet Value
definition: Oxybenzone is a benzophenone derivative used as a sunscreen agent. Oxybenzone absorbs UVB and UVA II rays, resulting in a photochemical excitation and absorption of energy. Upon return to ground state, the absorbed energy results in emission of longer wavelength radiation and decreased skin penetration of radiation which reduces the risk of DNA damage.
editorial note: Duplicate of OXB?
notation: BP3

Biological Relative
type: Class
subclass of: Relative
definition: Being from the same biological kinship as another person. In that aspect, consanguinity is the quality of being descended from the same ancestor as another person.

Eats Canned Food
type: Class
subclass of: food packaging
subclass of: Eating or Drinking
subclass of: Restriction
  on property: SIO_000230
  some values from: Canned Food Product
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
comment: The act of eating food that has been packaged in a metal container.
notation: HHEAR_9

Childhood Period
type: Class
subclass of: Childhood
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000582
definition: The age span ranging from birth to adolescence

Cotinine (total)
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes Cotinine (total)
editorial note: To Do: align with CHEBI.
notation: COTT

Cousin
type: Class
subclass of: Relative
type: NamedIndividual
type: Quality Value
definition: A person belonging to the same extended family.
notation: HHEAR_354

Education By Highest Grade Attained
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Variable
was approved by: PER-Jeanette-Stingone
definition: The subclasses of this class are used to denote the highest grade of education achieved for a subject.

Elective Caesarian Section
type: Class
subclass of: Caesarian Section
type: NamedIndividual
type: Quality Value
definition: A caesarian section that was chosen by the mother but was not medically necessary.
notation: HHEAR_19

Eats Fast Food
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Whether or not fast food is consumed.
notation: HHEAR_16

First Trimester
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalStarts
  some values from: Pregnancy
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
definition: From pregnancy week 1 through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the embryo and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus).

Eats Fresh Vegetables
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Whether or not Fresh Vegetables are consumed.
notation: HHEAR_29

obsolete: Gestational Age at Birth
type: Class
equivalent class: Class
  intersection of: EFO_0005112
  intersection of: Restriction
    on property: SIO_000793
    all values from: Birth
subclass of: EFO_0005112
deprecated: true
definition: Describes how far along a pregnancy is, usually measured in weeks, as measured at birth.

High School or Less
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Education Level of High School or Less
notation: HHEAR_33

Post-Secondary Education
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: College or university education beyond the successful completion of high school or grammar school, or the attainment of an approved equivalent
notation: HHEAR_31

Mandelic acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes Mandelic acid
editorial note: To Do: align with CHEBI.
notation: MA

Mandelic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes Mandelic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMAD

Maternal Weight Gain
type: Class
subclass of: Pregnancy Characteristic
subclass of: Difference of Weights
was approved by: PER-Jeanette-Stingone
definition: The amount of weight gained during a pregnacy.

Mercapturic acids of 1, 3-butadiene
type: Class
subclass of: Tobacco Metabolite
comment: This class denotes Mercapturic acids of 1, 3-butadiene
notation: HEMA

Metal
type: Class
subclass of: Element
definition: For environmental purposes, HHEAR metals are metals and metalliods, as originally defined in CHEAR.

N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-A-S-(1-HydrxMet)-2-Prpn)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMB1

N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-A-S-(3-hydrxprpl-1-metl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCPMM

N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ac-S-(2-Hydrxy-3-butnyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMB2

N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S- (3, 4-Dihidxybutl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCDHB

N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(2-Hydroxyethyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCHEM

N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(2-carbamoylethyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCAAM

N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(2-hydroxypropyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCHP2

N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(3-Hydroxypropyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCHPM

N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(N-methlcarbamoyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCAMC

N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Ace-S-(dimethylphenyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCDPM

N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acel-S-(2, 2-Dichlorvinyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOC2DC

N-Acetyl-S- (2-carboxyethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S- (2-carboxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: CEMA

N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S- (3, 4-dihydroxybutyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: DHBMA

N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S- (3-hydroxypropyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: HPMA

N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(1, 2-dichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: DCVMA12

N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: MHBMA1

N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(1-phenyl-2-hydroxyethyl-L-cysteine + N-Acetyl-S-(2-phenyl-2-hydroxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: PHEMA

N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2, 2-dichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: DCVMA22

N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2, 4-dimethylphenyl)-L-cysteine + N-Acetyl-S-(2, 5-dimethylphenyl)-L-cysteine + N-Acetyl-S-(3, 4-dimethylphenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: DPMA

N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(2-Carbxyethyl)-L-Cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCCEM

N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: GAMA

N-Acetyl-S-(2-cyanoethyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2-cyanoethyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: CYMA

N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: MHBMA2

N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: HPMA2

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: HPMMA

N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: MHBMA3

N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: AMCC

N-Acetyl-S-(benzyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(benzyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: BMA

N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(benzyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCBMA

N-Acetyl-S-(n-propyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(n-propyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: BPMA

N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(n-propyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCBPM

N-Acetyl-S-(phenyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(phenyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: PMA

N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(phenyl)-L-cysteine(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCPMA

N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-Acetyl-S-(trichlorovinyl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCTCV

N-Acetyl-S-(trichlorovinyl)-L-cysteine
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-Acetyl-S-(trichlorovinyl)-L-cysteine
editorial note: To Do: align with CHEBI.
notation: TCVMA

N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-ac-S-(2-carbmo-2-hydxel)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCGAM

N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes N-ace-S-(phenl-2-hydxyetl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMB3
notation: VOCPHE

N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-acel-S-(1, 2-dichlorovinl)-L-cys(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOC1DC

N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes N-acetyl-S-(2-cyanoethyl)-L-cyst(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCCYM

Nicotine (total)
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes Nicotine (total)
editorial note: To Do: align with CHEBI.
notation: NICT

No Formal Education
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Has not been educated in a formal setting.
notation: HHEAR_57

No Insurance / Self-funded
type: Class
subclass of: Private Insurance or Self Pay
subclass of: Public or No Insurance
type: NamedIndividual
type: Quality Value
comment: This class denotes No Insurance / Self-funded
notation: HHEAR_89

Non-Biological Relative
type: Class
subclass of: Relative
definition: People that are considered relatives but are not related by blood. This includes relatives by marriage, adoption, or fosterage.

Perfluroundecanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
comment: This class denotes Perfluroundecanoic acid
notation: PFUNDA

Phenylglyoxylic acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes Phenylglyoxylic acid
editorial note: To Do: align with CHEBI.
notation: PGA

Phenylglyoxylic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes Phenylglyoxylic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCPHG

Planned Caesarian Section
type: Class
subclass of: Caesarian Section
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Planned caesarian section.
notation: HHEAR_18

Post-Pregnancy
type: Class
subclass of: From Birth
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMetBy
  some values from: Birth
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000582
was approved by: PER-Jeanette-Stingone
definition: The period after birth.

Pre-Pregnancy
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMetBy
  some values from: Pregnancy
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
definition: The time before a pregnancy.

Prenatal Nonsmoker
type: Class
subclass of: Non-smoker
type: NamedIndividual
type: Quality Value
definition: Could be a former smoker or a non-smoker, so neither should be encoded as the superclass.
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
notation: HHEAR_76

Prenatal Smoker
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
definition: The quality of having smoked while being pregnant.
editorial note: Should this be a subClassOf PregnancyCharactistic as well?
notation: HHEAR_77

Private Insurance
type: Class
subclass of: Private Insurance or Self Pay
type: NamedIndividual
type: Quality Value
comment: This class denotes Private Insurance
notation: HHEAR_103

Quit Smoking
type: Class
subclass of: Previous Smoker
type: NamedIndividual
type: Quality Value
definition: Quit Smoking Cigarettes
notation: HHEAR_82

Repeat Caesarian Section
type: Class
subclass of: Caesarian Section
type: NamedIndividual
type: Quality Value
definition: Had Repeat Caesarian Section
notation: HHEAR_21

Second Trimester
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalDuring
  some values from: Pregnancy
subclass of: Restriction
  on property: intervalMetBy
  some values from: First Trimester
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
definition: From week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided with high-quality medical care.

Spontaneous Caesarian Section
type: Class
subclass of: Caesarian Section
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Had a spontaneous caesarian section
notation: HHEAR_22

Stress
type: Class
subclass of: Stress Frequency
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Whether or not a person gets stressed.
notation: HHEAR_92

Technical School
type: Class
subclass of: Education
subclass of: Associate's Degree or Technical Degree
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical School.
notation: HHEAR_96

Third Trimester
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalFinishes
  some values from: Pregnancy
subclass of: Restriction
  on property: intervalMetBy
  some values from: Second Trimester
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
definition: From 29 weeks through 40 weeks.

Total nicotine
type: Class
subclass of: Tobacco Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes Total nicotine
editorial note: Duplicate of NIC?
notation: TNIC

Underweight/Normal
type: Class
subclass of: Body Weight Quality
subclass of: Restriction
  on property: SIO_000011
  some values from: Restriction
    on property: SIO_000008
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: NamedIndividual
type: Quality Value
comment: This class denotes Underweight/Normal
notation: HHEAR_100

Unknown Education Level
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Level of Education is not known
notation: HHEAR_101

Unplanned Caesarian Section
type: Class
subclass of: Caesarian Section
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Had an unplanned caesarian section.
notation: HHEAR_23

Vaginal Birth
type: Class
subclass of: Pregnancy Characteristic
subclass of: Route Of Delivery
subclass of: SIO_000582
type: NamedIndividual
type: Quality Value
definition: Had a birthing occur via the vagina.
editorial note: Again, can we add a delivery class
notation: HHEAR_24

diethyldithiophosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes diethyldithiophosphate
editorial note: To Do: align with CHEBI.
notation: DEDP

diethylphosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes diethylphosphate
editorial note: To Do: align with CHEBI.
notation: DEP

diethylthiophosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes diethylthiophosphate
editorial note: To Do: align with CHEBI.
notation: DETP

dimethyldithiophosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes dimethyldithiophosphate
editorial note: To Do: align with CHEBI.
notation: DMDP

dimethylphosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes dimethylphosphate
editorial note: To Do: align with CHEBI.
notation: DMP

dimethylthiophosphate
type: Class
subclass of: Dialkyl Phosphate Pesticide Metabolite
type: NamedIndividual
type: Facet Value
comment: This class denotes dimethylthiophosphate
editorial note: To Do: align with CHEBI.
notation: DMTP

mono (6-COOH-2-methylheptyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono (6-COOH-2-methylheptyl) phthalate
notation: MCOMHP

mono (7-COOH-2-methyloctyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono (7-COOH-2-methyloctyl) phthalate
notation: MCOMOP

mono(7-carboxyheptyl)phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono(7-carboxyheptyl)phthalate
notation: mCHpP

mono-2-heptyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-2-heptyl phthalate
notation: mHpP

mono-carboxy isononyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-carboxy isononyl phthalate
notation: mCINP

mono-carboxy isooctyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-carboxy isooctyl phthalate
notation: mCIOP

mono-isodecyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-isodecyl phthalate
notation: mIDP

t, t-Muconic acid(ng/mL)
type: Class
subclass of: Volatile Organic Compound
comment: This class denotes t, t-Muconic acid(ng/mL)
editorial note: To Do: align with CHEBI.
notation: VOCMUC

trans, trans -Muconic acid
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes trans, trans -Muconic acid
editorial note: To Do: align with CHEBI.
notation: MU

1-hydroxybenz[a]anthacene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 1-hydroxybenz[a]anthacene
editorial note: Only found in one journal article, no where else. Maybe mis-spelled?
notation: BAA1

1-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 1-hydroxybenzo[c]-phenanthrene
notation: BCP1

2-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-hydroxybenzo[c]-phenanthrene
notation: BCP2

3-hydroxybenzo[c]-phenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-hydroxybenzo[c]-phenanthrene
notation: BCP3

3-hydroxychrysene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 3-hydroxychrysene
notation: CHRY3

Adopted
type: Class
subclass of: Non-Biological Relative
definition: Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents, and, in so doing, permanently transfers all rights and responsibilities, along with filiation, from the biological parent or parents.

Ancestor
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Descendant
was approved by: PER-Jeanette-Stingone
definition: An ancestor or forebear is a parent or (recursively) the parent of an ancestor (i.e., a grandparent, great-grandparent, great-great-grandparent, and so forth). Ancestor is "any person from whom one is descended. In law the person from whom an estate has been inherited."

Benzo[a]pyrene tetraol
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes Benzo[a]pyrene tetraol
notation: BAPT

Birth
type: Class
subclass of: Beginning
subclass of: From Birth
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMetBy
  some values from: Pregnancy
was approved by: PER-Jeanette-Stingone
definition: The ending of a pregnancy by one or more babies leaving a woman's uterus by vagina passage or c-section.

Descendant
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Ancestor
was approved by: PER-Jeanette-Stingone
definition: The child of a human, or any grandchild, great-grandchild, and so on.

Fenton Weighted Z-Score
type: Class
subclass of: Birth Outcome
subclass of: Birth Weight Z-Score
subclass of: SIO_001245
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Fenton Preterm Growth Chart
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Birth Weight
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: EFO_0005112
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Derived from Birth Weight, Gestational Age, and Child Sex

Forceps-Assisted Birth
type: Class
subclass of: Vaginal Birth
type: NamedIndividual
type: Quality Value
definition: A vaginal birth with the assistance of forceps to extract the baby.
notation: HHEAR_25

Foster
type: Class
subclass of: Non-Biological Relative
definition: Fosterage, the practice of a family bringing up a child not their own, differs from adoption in that the child's parents, not the foster-parents, remain the acknowledged parents. In many modern western societies foster care can be organized by the state to care for children with troubled family backgrounds, usually on a temporary basis. In many pre-modern societies fosterage was a form of patronage, whereby influential families cemented political relationships by bringing up each other's children, similar to arranged marriages, also based on dynastic or alliance calculations.

Gas Chromatographer-Tandem Mass Spectrometer
type: Class
subclass of: Tandem Mass Spectrometer
subclass of: Gas Chromatographer–Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: MS/MS is the combination of two mass analyzers in one mass spec instrument.

Graduated From High School
type: Class
subclass of: High School or Some College
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: The quality of having graduated from High School
notation: HHEAR_32

High-Performance Liquid Chromatography-Mass Spectrometry
type: Class
subclass of: Mass Spectrometer
subclass of: High-Performance Liquid Chromatography
subclass of: Liquid Chromatography–Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Liquid chromatography–mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography - MS systems are popular in chemical analysis because the individual capabilities of each technique are enhanced synergistically. While liquid chromatography separates mixtures with multiple components, mass spectrometry provides structural identity of the individual components with high molecular specificity and detection sensitivity. This tandem technique can be used to analyze biochemical, organic, and inorganic compounds commonly found in complex samples of environmental and biological origin. Therefore, LC-MS may be applied in a wide range of sectors including biotechnology, environment monitoring, food processing, and pharmaceutical, agrochemical, and cosmetic industries.

Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: Tandem Mass Spectrometer
subclass of: Liquid Chromatography–Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS is the combination of two mass analyzers in one mass spec instrument.

Mercapturic acid of benzene
type: Class
subclass of: Volatile Organic Compound
type: NamedIndividual
type: Facet Value
comment: This class denotes Mercapturic acid of benzene
notation: SPMA

Mercapturic acids of acrolein and crotonaldehyde
type: Class
subclass of: polycyclic hydrocarbon
comment: This class denotes Mercapturic acids of acrolein and crotonaldehyde
notation: AMA

PCB138
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB138
notation: PCB138

PCB153
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB153
notation: PCB153

PCB180
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes PCB180
notation: PCB180

Preschool
type: Class
subclass of: Education By Highest Grade Attained
type: NamedIndividual
type: Quality Value
definition: Finished preschool.
notation: HHEAR_112

Sibling
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Sibling
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: One of two or more individuals having one or both parents in common. A male sibling is a brother, and a female sibling is a sister. In most societies throughout the world, siblings often grow up together, thereby facilitating the development of strong emotional bonds. The emotional bond between siblings is often complicated and is influenced by factors such as parental treatment, birth order, personality, and personal experiences outside the family. However, there are cases where siblings grow up in separate homes, in different environments.
notation: HHEAR_353

Some Elementary School
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended Some Elementary School
notation: HHEAR_86

Some High School
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Education Level of Some High School
notation: HHEAR_87

Some Middle School
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended Some Middle School
notation: HHEAR_90

Step
type: Class
subclass of: Non-Biological Relative
definition: A stepfamily is a family where at least one parent has children that are not genetically related to the other spouse or partner. Either one parent may have children from a previous relationship. Children in a stepfamily may live with one biological parent, or they may live with each biological parent for a period of time. In addition, visitation rights mean that children in stepfamilies often have contact with both biological parents, even if they permanently live with only one. A child is referred to as the stepchild, stepdaughter or stepson of their biological parent's new spouse, and that person as the stepparent, stepfather or stepmother of the child. A stepfather is the husband of one's mother, and not one's biological father. A stepmother is the wife of one's father, and not one's biological mother. A step-grandmother is the wife of one's grandfather, and not one's biological grandmother. A step-grandfather is the husband of one's grandmother, and not one's biological grandfather. Similarly, a stepbrother is the son of a stepparent who one is not biologically related to. A stepsister is the daughter of a stepparent to whom one is not biologically related. A step-grandson is the son of a stepson or stepdaughter who one is not biologically related to. A step-granddaughter is the daughter of a stepson or stepdaughter who one is not biologically related. A parent's spouse of the same sex may also count as a stepparent.

Technical Post Junior College
type: Class
subclass of: Technical School
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post Junior College
notation: HHEAR_93

Ultra Performance Liquid Chromatography - Mass Spectrometer
type: Class
subclass of: Mass Spectrometer
subclass of: Ultra High Performance Liquid Chromatography Instrument
was approved by: PER-Jim-McCusker
comment: This class denotes Ultra Performance Liquid Chromatography - Mass Spectrometer

Conception
type: Class
subclass of: Beginning
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
was approved by: PER-Jeanette-Stingone
definition: When a sperm fertilizes an egg

Education Grade 1
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Elementary School
type: NamedIndividual
type: Quality Value
definition: Finished grade 1
notation: HHEAR_113

Education Grade 2
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Elementary School
type: NamedIndividual
type: Quality Value
definition: Finished grade 2
notation: HHEAR_114

Education Grade 3
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Elementary School
type: NamedIndividual
type: Quality Value
definition: Finished grade 3
notation: HHEAR_115

Education Grade 5
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
definition: Finished grade 5
notation: HHEAR_117

Education Grade 6
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
definition: Finished grade 6
notation: HHEAR_118

Education Grade 7
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
definition: Finished grade 7
notation: HHEAR_119

Finished Elementary School
type: Class
subclass of: Finished Elementary Grade 4
type: NamedIndividual
type: Quality Value
was approved by: PER-Jim-McCusker
definition: Finished Elementary School
notation: HHEAR_15

Normal Weight
type: Class
subclass of: Body Weight Quality
subclass of: Underweight/Normal
subclass of: Restriction
  on property: SIO_000011
  some values from: Restriction
    on property: SIO_000008
    some values from: Class
      intersection of: Body Mass Index
      intersection of: Restriction
        on property: STATO_0000129
        some values from: Datatype
type: NamedIndividual
type: Quality Value
definition: Adult normal weight is defined as having a BMI between 18.5 and 25 kg/m^2; Child normal weight is defined as greater than or equal to the 5th percentile but less than the 85th percentile for age, gender and height.
notation: HHEAR_61

Pregnancy
type: Class
subclass of: Life Stage
subclass of: Maternal Prenatal Stage
subclass of: Pregnancy Characteristic
subclass of: From Conception
subclass of: Study Population
subclass of: Pregnancy or Followup
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMetBy
  some values from: Pre-Pregnancy
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
type: NamedIndividual
type: Facet
was approved by: PER-Jeanette-Stingone
definition: The time during which one or more offspring develops inside a woman.

Technical Post Primary School
type: Class
subclass of: High School or Less
subclass of: Technical School
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post Primary School
notation: HHEAR_95

Technical Post-Middle School
type: Class
subclass of: High School or Less
subclass of: Technical School
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: Attended a Technical Post-Middle School.
notation: HHEAR_94

Child
type: Class
subclass of: Descendant
subclass of: Study Population
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Parent
type: NamedIndividual
type: Facet
was approved by: PER-Jeanette-Stingone
definition: A relationship with a parent (such as sons and daughters of any age).

Finished Elementary Grade 4
type: Class
subclass of: Graduated From High School
type: NamedIndividual
type: Quality Value
definition: Finished grade 4
notation: HHEAR_116

Head Of Household
type: Class
subclass of: Demographic
subclass of: SIO_000016
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Household
was approved by: PER-Jeanette-Stingone
definition: Head of Household is a filing status for individual United States taxpayers. To use the Head of Household filing status, a taxpayer must: (1) Be unmarried or considered unmarried at the end of the year (2) Have paid more than half the cost of keeping up a home for the tax year (either one's own home or the home of a qualifying parent) (3) Usually have a qualifying person who lived with the head in the home for more than half of the tax year unless the qualifying person is a dependent parent.
definition: The Person is the head of Household

Parent
type: Class
subclass of: Ancestor
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000485
    intersection of: Restriction
      on property: SIO_000228
      all values from: Child
was approved by: PER-Jeanette-Stingone
definition: A parent is the caretaker of a child (where "child" refers to offspring, not necessarily age). A biological parent is a person whose gamete resulted in a child, a male through the sperm, and a female through the ovum. Parents are first-degree relatives and have 50% genetic meet. A female can also become a parent through surrogacy. Some parents may be adoptive parents, who nurture and raise an offspring, but are not actually biologically related to the child. Orphans without adoptive parents can be raised by their grandparents or other family members.

Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: Tandem Mass Spectrometer
subclass of: Ultra Performance Liquid Chromatography - Mass Spectrometer
was approved by: PER-Jim-McCusker
comment: This class denotes Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometer

High Performance Liquid Chromatography - Tandem Mass Spectrometer
type: Class
subclass of: High-Performance Liquid Chromatography-Mass Spectrometry
subclass of: Liquid Chromatography - Tandem Mass Spectrometer
was approved by: PER-Jim-McCusker
definition: Liquid chromatography and tandem Mass Spectrometry. MS/MS (Tandem MS) is the combination of two mass analyzers in one mass spec instrument.

Quit Smoking After Pregnancy
type: Class
subclass of: Pregnancy Characteristic
subclass of: Prenatal Smoker
subclass of: Quit Smoking
type: NamedIndividual
type: Quality Value
definition: Quit Smoking After Pregnancy
notation: HHEAR_80

Quit Smoking Before Pregnancy
type: Class
subclass of: Pregnancy Characteristic
subclass of: Prenatal Nonsmoker
subclass of: Quit Smoking
type: NamedIndividual
type: Quality Value
definition: A Previous Smoker who Quit Smoking Before Pregnancy
notation: HHEAR_81

Daughter
type: Class
subclass of: Child
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
definition: The female offspring in relation to her parents.

Father
type: Class
subclass of: Parent
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: Quality Value
was approved by: PER-Jeanette-Stingone
definition: The male parent of a child. Besides the paternal bonds of a father to his children, the father may have a parental legal and social relationship with the child that carries with it certain rights and obligations. An adoptive father is a male who has become the child's parent through the legal process of adoption. A biological father is the male genetic contributor to the creation of the baby, through sexual intercourse or sperm donation. A biological father may have legal obligations to a child not raised by him, such as an obligation of monetary support. A putative father is a man whose biological relationship to a child is alleged but has not been established. A stepfather is a male who is the husband of a child's mother and they may form a family unit, but who generally does not have the legal rights and responsibilities of a parent in relation to the child.
notation: HHEAR_188

Mother
type: Class
subclass of: Parent
subclass of: Study Population
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: Quality Value
type: Facet
was approved by: PER-Jeanette-Stingone
definition: A mother is the female parent of a child. Mothers are women who inhabit or perform the role of bearing some relation to their children, who may or may not be their biological offspring. Thus, dependent on the context, women can be considered mothers by virtue of having given birth, by raising their child(ren), supplying their ovum for fertilisation, or some combination thereof. Such conditions provide a way of delineating the concept of motherhood, or the state of being a mother. Women who meet the third and first categories usually fall under the terms 'birth mother' or 'biological mother', regardless of whether the individual in question goes on to parent their child. Accordingly, a woman who meets only the second condition may be considered an adoptive mother, and those who meet only the third a surrogacy mother. The above concepts defining the role of mother are neither exhaustive nor universal, as any definition of 'mother' may differ based on how social, cultural, and religious roles are defined.
notation: HHEAR_189

Son
type: Class
subclass of: Child
subclass of: Restriction
  on property: isRoleOf
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
definition: A son is a male offspring; a boy or man in relation to his parents.

Birth Weight
type: Class
equivalent class: Class
  intersection of: SIO_000279
  intersection of: Restriction
    on property: SIO_000793
    all values from: Birth
subclass of: Clinical Measurement
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Birth Weight

Beginning
type: Class
subclass of: Relative Time
subclass of: Restriction
  on property: SIO_000300
  has value: 1
definition: A time relative to the beginning of an event

From Birth
type: Class
subclass of: Relative Time
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000582
definition: A time in relation to a birth

From Conception
type: Class
subclass of: Relative Time
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
definition: A time in relation to a conception

Relative Time
type: Class
subclass of: SIO_000391
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: SIO_000006
definition: A time in relation to an event

Analysis
type: Class
subclass of: Analyte
definition: The value contains concentrations from the study sample

Quality Control
type: Class
subclass of: Analyte
definition: The value contains quality control data

Replicate
type: Class
subclass of: Analyte
definition: The value contains data for a repeat of the study sample

White Hispanic
type: Class
subclass of: White
type: NamedIndividual
type: Quality Value
definition: White and Hispanic
notation: HHEAR_145

Non-White Hispanic
type: Class
subclass of: Hispanic or Latino Ethnicity
subclass of: Non-White
type: NamedIndividual
type: Quality Value
definition: Non-White and Hispanic
notation: HHEAR_146

Owns Home
type: Class
subclass of: Home Ownership
type: NamedIndividual
type: Quality Value
definition: This person owns the home they live in.
notation: HHEAR_147

Home Ownership
type: Class
subclass of: Socioeconomic Status
type: NamedIndividual
type: Quantity Variable
type: Facet
definition: Who owns the home they live in.

Renter
type: Class
subclass of: Home Ownership
type: NamedIndividual
type: Quality Value
definition: This person rents the home they live in.
notation: HHEAR_148

Non-White
type: Class
subclass of: SIO_001015
type: NamedIndividual
type: Quality Value
definition: A race other than white.
notation: HHEAR_149

Social Affect + Restricted and Repetitive Behavior Total
type: Class
subclass of: CAO_01168
type: NamedIndividual
type: Quantity Variable
definition: Total Standardized Autism Diagnostic Observation Schedule (ADOS) score.

ADOS calibrated severity score
type: Class
subclass of: CAO_01168
type: NamedIndividual
type: Quantity Variable
definition: Calibrated severity score on the Total Standardized Autism Diagnostic Observation Schedule (ADOS).

Prenatal Vitamin Use
type: Class
subclass of: nutrition intake
type: NamedIndividual
type: Quality Value
definition: Prenatal vitamins are supplements that contain daily vitamins and minerals needed by mothers before and during pregnancy.
notation: HHEAR_694

Age Equivalent
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
definition: Age Equivalent is the individual's ability; skill, knowledge, or measurement expressed as the age at which most individuals reach the same level (age norm). The Age Norm is the average score of a particular test completed by children of a given chronological age.

Mean Concentration
type: Class
subclass of: SIO_001088
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
definition: The mean aggregate of multiple concentration measurements of a single substance within a compound substance.

E-Cigarette Use
type: Class
subclass of: Active Smoker
type: NamedIndividual
type: Quality Variable
comment: This class denotes E-Cigarette Use

Occasional E-Cigarette Use
type: Class
subclass of: E-Cigarette Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Occasional E-Cigarette Use
notation: HHEAR_155

Daily E-Cigarette Use
type: Class
subclass of: E-Cigarette Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Daily E-Cigarette Use
notation: HHEAR_156

Daily Smoker
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
comment: This class denotes Daily Smoker
notation: HHEAR_157

Occasional Smoker
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
comment: This class denotes Occasional Smoker
notation: HHEAR_158

Grandmother
type: Class
subclass of: Ancestor
type: NamedIndividual
type: Quality Value
definition: The mother of your father or mother.
notation: HHEAR_190

Aunt
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: Quality Value
definition: The sister of your father or mother or the wife of your uncle.
notation: HHEAR_191

Uncle
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: Quality Value
definition: The brother of your father or mother or the husband of your aunt.
notation: HHEAR_192

Grandfather
type: Class
subclass of: Ancestor
type: NamedIndividual
type: Quality Value
definition: The father of your father or mother.
notation: HHEAR_682

Annual Income $5,000 or Less
type: Class
subclass of: Annual Income $10,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 5000
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income at or below $5,000
notation: HHEAR_159

Annual Income $5,001 to $15,000
type: Class
subclass of: Annual Income $20,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 15000
subclass of: Restriction
  on property: minValue
  has value: 5001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $5,001 and $15,000
notation: HHEAR_160

Annual Income $15,001 to $30,000
type: Class
subclass of: Annual Income $39,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 30000
subclass of: Restriction
  on property: minValue
  has value: 15001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $15,001 and $30,000
notation: HHEAR_161

Annual Income $30,001 to $50,000
type: Class
subclass of: Annual Income $30,000 to $60,000
subclass of: Annual Income $25,000 to $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 50000
subclass of: Restriction
  on property: minValue
  has value: 30001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $30,001 and $50,000
notation: HHEAR_162

Annual Income $50,001 to $75,000
type: Class
subclass of: Annual Income $50,000 to $99,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 75000
subclass of: Restriction
  on property: minValue
  has value: 50001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $50,001 and $75,000
notation: HHEAR_163

Annual Income $75,001 to $90,000
type: Class
subclass of: Annual Income $75,000 to $99,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 90000
subclass of: Restriction
  on property: minValue
  has value: 75001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $75,001 and $90,000
notation: HHEAR_164

Annual Income $90,001 to $120,000
type: Class
subclass of: Annual Income $75,000 to $149,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 120000
subclass of: Restriction
  on property: minValue
  has value: 90001
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income bwtween $90,001 and $120,000
notation: HHEAR_165

Annual Income More Than $120,000
type: Class
subclass of: Annual Income More Than $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 120000
type: NamedIndividual
type: Quality Value
definition: Personal or family annual income greater than $120,000
notation: HHEAR_166

Single-Family House
type: Class
subclass of: Residential Building
subclass of: Living Quarters
type: NamedIndividual
type: Quality Value
definition: A residential building designed to hold one family.
notation: HHEAR_175

Multi-Family House
type: Class
subclass of: Residential Building
subclass of: Living Quarters
type: NamedIndividual
type: Quality Value
definition: A residential building designed to hold more than one family.
notation: HHEAR_176

Metabolite
type: Class
subclass of: Analyte
definition: The intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and pheromones). A primary metabolite is directly involved in normal "growth", development, and reproduction. Ethylene is an example of a primary metabolite produced in large-scale by industrial microbiology. A secondary metabolite is not directly involved in those processes, but usually has an important ecological function. Examples include antibiotics and pigments such as resins and terpenes etc. Some antibiotics use primary metabolites as precursors, such as actinomycin which is created from the primary metabolite, tryptophan.

Health Outcome
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
comment: This class denotes Health Outcome

Caregiver
type: Class
subclass of: Demographic
subclass of: SIO_000016
definition: a paid or unpaid and without formal training member of a person's social network who helps them with activities of daily living. Caregiving is most commonly used to address impairments related to old age, disability, a disease, or a mental disorder.

Some Postgraduate
type: Class
subclass of: College Graduate or Higher
subclass of: Restriction
  on property: SIO_000230
  some values from: NCIT C92860
type: NamedIndividual
type: Quality Value
definition: Has begun postgraduate (masters, doctorate, etc) and may or may not have matriculated with a graduate degree.
notation: HHEAR_187

Childhood Baseline
type: Class
subclass of: Study Baseline
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study set to the initial point which occurs during the study subject's childhood period.

Childhood Followup
type: Class
subclass of: Study Followup
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Baseline
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the initial baseline of the study and occurs during the study subject's childhood period.

Study Followup
type: Class
subclass of: Study Activity
subclass of: Pregnancy or Followup
definition: A point in a study where data is gathered after the initial baseline.

Birth Year
type: Class
subclass of: SIO_000428
type: NamedIndividual
type: Quality Value
definition: The year in which a person was born.
notation: HHEAR_198

Birthplace
type: Class
subclass of: Demographic
subclass of: Location
type: NamedIndividual
type: Quality Variable
definition: The place where a person was born.

Non-ecigarette user
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
definition: Doesn't use e-cigarettes.
notation: HHEAR_199

Tobacco Cessation Intervention Group
type: Class
subclass of: Experimental Group
type: NamedIndividual
type: Quality Value
definition: A group receiving a tobacco cessation intervention that is being tested in a study.
notation: HHEAR_202

Limit of Quantitation
type: Class
subclass of: SIO_001088
definition: The Limit of Quantitation is the lowest concentration at which the analyte can not only be reliably detected but at which some predefined goals for bias and imprecision are met. The LoQ may be equivalent to the LoD or it could be at a much higher concentration. (Source: Limit of Blank, Limit of Detection and Limit of Quantitation, David A Armbruster and Terry Pry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556583/)

Air Pollutant
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: Quality Variable
type: Facet
comment: This class denotes Air Pollutant

Some College or Technical School
type: Class
equivalent class: Class
  union of: Some College
  union of: Some Technical School
subclass of: Education
subclass of: Class
  union of: Some College
  union of: Some Technical School
type: NamedIndividual
type: Quality Value
comment: This class denotes Some College or Technical School
notation: HHEAR_203

Annual Mean Concentration
type: Class
subclass of: Mean Concentration
type: NamedIndividual
type: Quality Variable
comment: This class denotes Annual Mean Concentration

Adulthood Period
type: Class
subclass of: Adult
definition: Time period that begins after adolesence and continues until death

microgram per cubic meter
type: Class
subclass of: mass density unit
type: NamedIndividual
type: SIO_000074
type: NodeShape
comment: Microgram per cubic meter; a unit of mass density.
notation: µg/m3

Annual Income $5,001 to $10,000
type: Class
subclass of: Annual Income $5,001 to $15,000
subclass of: Annual Income $10,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 10000
subclass of: Restriction
  on property: minValue
  has value: 5001
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $5,001 to $10,000
notation: HHEAR_204

Annual Income $10,001 to $20,000
type: Class
subclass of: Annual Income $20,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 20000
subclass of: Restriction
  on property: minValue
  has value: 10001
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $10,001 to $20,000
notation: HHEAR_205

Annual Income $20,001 to $40,000
type: Class
subclass of: Annual Income $20,000 to $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 40000
subclass of: Restriction
  on property: minValue
  has value: 20001
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $20,001 to $40,000
notation: HHEAR_206

Annual Income $40,001 to $70,000
type: Class
subclass of: Annual Income $40,000 to $74,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 70000
subclass of: Restriction
  on property: minValue
  has value: 40001
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $40,001 to $70,000
notation: HHEAR_207

Annual Income More Than $70,001
type: Class
subclass of: Annual Income More Than $65,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 70001
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income More Than $70,001
notation: HHEAR_208

Indoor Air
type: Class
subclass of: air
subclass of: Restriction
  on property: SIO_000128
  some values from: ExO_0000019
comment: This class denotes Indoor Air

Outdoor Air
type: Class
subclass of: air
subclass of: Restriction
  on property: SIO_000128
  some values from: ExO_0000020
comment: This class denotes Outdoor Air

Subtrahend
type: Class
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
definition: In a difference expression, the subtrahend is the quantity or number to be subtracted from another.

Minuend
type: Class
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
definition: In a difference expression, the minuend is the quantity or number from which another is to be subtracted.

Difference of Z-Scores
type: Class
subclass of: Difference
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Z-Score
    intersection of: Subtrahend
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Z-Score
    intersection of: Minuend
type: NamedIndividual
type: Quantity Variable
definition: The arithmetic difference of two Z-Scores

White Non-Hispanic
type: Class
subclass of: White
type: NamedIndividual
type: Quality Value
comment: This class denotes White Non-Hispanic
notation: HHEAR_214

Less than High School
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
comment: This class denotes Less than High School
notation: HHEAR_215

Black Non-Hispanic
type: Class
subclass of: Black or African American
subclass of: Non-Hispanic Ethnicity
type: NamedIndividual
type: Quality Value
comment: This class denotes Black Non-Hispanic
notation: HHEAR_216

Asian Non-Hispanic
type: Class
subclass of: Asian
subclass of: Non-Hispanic Ethnicity
type: NamedIndividual
type: Quality Value
comment: This class denotes Asian Non-Hispanic
notation: HHEAR_217

American Indian Non-Hispanic
type: Class
subclass of: American Indian Or Alaskan Native
subclass of: Non-Hispanic Ethnicity
type: NamedIndividual
type: Quality Value
comment: This class denotes American Indian Non-Hispanic
notation: HHEAR_218

Annual Income $14,999 or Less
type: Class
subclass of: Annual Income $20,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 14999
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $14,999 or Less
notation: HHEAR_219

Annual Income $15,000 to $29,999
type: Class
subclass of: Annual Income $39,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 29999
subclass of: Restriction
  on property: minValue
  has value: 15000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $15,000 to $29,999
notation: HHEAR_220

Annual Income $30,000 to $49,999
type: Class
subclass of: Annual Income $30,000 to $60,000
subclass of: Annual Income $25,000 to $49,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 49999
subclass of: Restriction
  on property: minValue
  has value: 30000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $30,000 to $49,999
notation: HHEAR_221

Annual Income $50,000 to $99,999
type: Class
subclass of: Annual Income More Than $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 99999
subclass of: Restriction
  on property: minValue
  has value: 50000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $50,000 to $99,999
notation: HHEAR_222

Annual Income More Than $100,000
type: Class
subclass of: Annual Income More Than $95,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 100000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income More Than $100,000
notation: HHEAR_223

Difference of Weight-to-Length Z-Scores from 0 to 6 Months
type: Class
subclass of: Difference of Z-Scores
type: NamedIndividual
type: Quantity Variable
definition: The arithmetic difference between the weight-to-length Z-scores for a child taken at birth and at six months.

Eating or Drinking
type: Class
subclass of: nutrition intake
subclass of: Diet Quantity
type: NamedIndividual
type: Quality Variable
definition: The act of eating or drinking some food or beverage.

Eats Rice
type: Class
subclass of: Rice Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03301641
type: NamedIndividual
type: Quality Value
definition: The attribute of eating rice.
notation: HHEAR_224

Eats Fish Sticks
type: Class
subclass of: Fish Sticks Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03311701
type: NamedIndividual
type: Quality Value
definition: The attribute of eating fish sticks.
notation: HHEAR_225

Eats Oily Fish
type: Class
subclass of: Oily Fish Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: Oily Fish
type: NamedIndividual
type: Quality Value
definition: The attribute of eating oily fish.
notation: HHEAR_226

Eats Fresh Fish
type: Class
subclass of: Fresh Fish Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03315446
type: NamedIndividual
type: Quality Value
definition: The attribute of eating fresh fish.
notation: HHEAR_227

Eats Canned Fish
type: Class
subclass of: Eats Canned Food
subclass of: Canned Seafood Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03302764
type: NamedIndividual
type: Quality Value
definition: The attribute of eating canned fish.
notation: HHEAR_228

Eats Fried Fish
type: Class
subclass of: Fried Fish Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03310717
type: NamedIndividual
type: Quality Value
definition: The attribute of eating fried fish.
notation: HHEAR_229

Eats Shell Fish
type: Class
subclass of: Shell Fish Consumption
subclass of: Restriction
  on property: SIO_000369
  some values from: FOODON_03411433
type: NamedIndividual
type: Quality Value
definition: The attribute of eating shell fish.
notation: HHEAR_230

Oily Fish
type: Class
subclass of: fish
definition: Oily fish are fish that contain at least 2% fat by weight. (Oily Fish. (n.d.) Segen's Medical Dictionary. (2011))

Sustained Physical Activity
type: Class
subclass of: Physical Activity
type: NamedIndividual
type: Quality Variable
definition: Physical activity that is at least 30 minutes in duration.

Multi Residence Building
type: Class
subclass of: Residential Building
subclass of: Living Quarters
type: NamedIndividual
type: Quality Value
definition: A residential building that contains more than one apartment, town house, condo, or other single family dwelling space.
notation: HHEAR_231

2-4 Residence Building
type: Class
subclass of: Multi Residence Building
type: NamedIndividual
type: Quality Value
definition: A residential building that contains between two and four apartments, town houses, condos, or other single family dwelling spaces.
notation: HHEAR_232

5-10 Residence Building
type: Class
subclass of: Multi Residence Building
type: NamedIndividual
type: Quality Value
definition: A residential building that contains between five and ten apartments, town houses, condos, or other single family dwelling spaces.
notation: HHEAR_233

11 or More Residence Building
type: Class
subclass of: Multi Residence Building
type: NamedIndividual
type: Quality Value
definition: A residential building that contains eleven or more apartments, town houses, condos, or other single family dwelling spaces.
notation: HHEAR_234

Garage
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: Quality Value
definition: A building, or part of a building primarily used for housing a motor vehicle or vehicles.
notation: HHEAR_235

Born First
type: Class
subclass of: First
subclass of: Birth Order
type: NamedIndividual
type: Quality Value
definition: The first born child
notation: HHEAR_236

Born Second
type: Class
subclass of: Second
subclass of: Birth Order
type: NamedIndividual
type: Quality Value
definition: The second born child
notation: HHEAR_237

Born Third
type: Class
subclass of: Third
subclass of: Birth Order
type: NamedIndividual
type: Quality Value
definition: The third born child
notation: HHEAR_238

Born Fourth
type: Class
subclass of: Fourth
subclass of: Birth Order
type: NamedIndividual
type: Quality Value
definition: The fourth born child
notation: HHEAR_239

Born Fifth
type: Class
subclass of: Fifth
subclass of: Birth Order
type: NamedIndividual
type: Quality Value
definition: The fifth born child
notation: HHEAR_240

Born Sixth Or Later
type: Class
subclass of: Sixth
type: NamedIndividual
type: Quality Value
definition: The sixth or later born child
notation: HHEAR_241

First or Second Trimester
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
definition: The time period from pregnancy week 1 through 28 and includes conception.

Race or Ethnicity Combined
type: Class
equivalent class: Class
  union of: SIO_001014
  union of: SIO_001015
subclass of: Demographic
type: NamedIndividual
type: Quality Variable
definition: Race or ethinicity as a combined concept.

Pacific Islander or Native Hawaiian, non-Hispanic
type: Class
subclass of: Native Hawaiian or Other Pacific Islander
subclass of: Non-Hispanic Ethnicity
type: NamedIndividual
type: Quality Value
comment: This class denotes Pacific Islander or Native Hawaiian, non-Hispanic
notation: HHEAR_242

environmental e-cigarette smoke exposure measurement
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
subclass of: Tobacco Smoke Exposure
subclass of: EFO_0008360
type: NamedIndividual
type: Quality Variable
definition: Exposure to secondhand smoke via e-cigarettes

Asthma Severity Index Composite Score (CASI)
type: Class
subclass of: Questionnaire
subclass of: Asthma Severity
type: NamedIndividual
type: Quality Variable
definition: The Composite Asthma Severity Index (CASI) is a comprehensive severity scale combining multiple facets of asthma severity: impairment, risk, and treatment The CASI score, which was developed as a research tool for intervention studies, ranges from 0 to 20 points, with higher scores indicating higher levels of severity, and includes 5 domains: day symptoms and albuterol use, night symptoms and albuterol use, controller treatment, lung function measures, and exacerbations. (Source: Minimally Important Differences and Risk Levels for the Composite Asthma Severity Index Rebecca Z. Krouse, et al.)

FVC Best Value
type: Class
subclass of: forced vital capacity (FVC)
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quality Variable
definition: The best FVC value achieved by a subject during a series of FVC measurements.

FVC Predicted Value
type: Class
subclass of: forced vital capacity (FVC)
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quality Variable
definition: The expected or predicted FVC value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

FEV1 Best Value
type: Class
subclass of: forced expiratory volume
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quality Variable
definition: The best FEV1 value achieved by a subject during a series of FEV1 measurements

FEV1 Predicted Value
type: Class
subclass of: forced expiratory volume
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quality Variable
definition: The expected or predicted FEV1 value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

FEF 25-75 Best Value
type: Class
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quantity Variable
definition: The best FEF 25-75 value achieved by a subject during a series of FEF 25-75 measurements.

FEF 25-75 Predicted Value
type: Class
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000099
type: NamedIndividual
type: Quality Variable
definition: The expected or predicted FEF 25-75 value for a patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

Daily exposure to second hand smoke
type: Class
subclass of: Frequently exposed to second hand smoke
type: NamedIndividual
type: Quality Value
comment: This class denotes Daily exposure to second hand smoke
notation: HHEAR_250

Several times a week exposure to second hand smoke
type: Class
subclass of: Frequently exposed to second hand smoke
type: NamedIndividual
type: Quality Value
comment: This class denotes Several times a week exposure to second hand smoke
notation: HHEAR_251

Several times a month exposure to second hand smoke
type: Class
subclass of: Not Frequently Exposed to Second Hand Smoke
type: NamedIndividual
type: Quality Value
comment: This class denotes Several times a month exposure to second hand smoke
notation: HHEAR_252

Rarely exposed to second hand smoke
type: Class
subclass of: Not Frequently Exposed to Second Hand Smoke
type: NamedIndividual
type: Quality Value
comment: This class denotes Rarely exposed to second hand smoke
notation: HHEAR_253

Never exposed to second hand smoke
type: Class
subclass of: Second Hand Smoke Exposure by Frequency
subclass of: Has Not Been Exposed to Second Hand Smoke
type: NamedIndividual
type: Quality Value
comment: This class denotes Never exposed to second hand smoke
notation: HHEAR_254

Daily Exposure to Second Hand Smoke from E-cigarettes
type: Class
subclass of: environmental e-cigarette smoke exposure measurement
type: NamedIndividual
type: Quality Value
comment: This class denotes Daily Exposure to Second Hand Smoke from E-cigarettes
notation: HHEAR_255

Several times a week exposure to second hand smoke from E-cigarettes
type: Class
subclass of: environmental e-cigarette smoke exposure measurement
type: NamedIndividual
type: Quality Value
comment: This class denotes Several times a week exposure to second hand smoke from E-cigarettes
notation: HHEAR_256

Several times a month exposure to second hand smoke from E-cigarettes
type: Class
subclass of: environmental e-cigarette smoke exposure measurement
type: NamedIndividual
type: Quality Value
comment: This class denotes Several times a month exposure to second hand smoke from E-cigarettes
notation: HHEAR_257

Rarely exposed to second hand smoke from E-cigarettes
type: Class
subclass of: environmental e-cigarette smoke exposure measurement
type: NamedIndividual
type: Quality Value
comment: This class denotes Rarely exposed to second hand smoke from E-cigarettes
notation: HHEAR_258

Never exposed to second hand smoke from E-cigarettes
type: Class
subclass of: environmental e-cigarette smoke exposure measurement
type: NamedIndividual
type: Quality Value
comment: This class denotes Never exposed to second hand smoke from E-cigarettes
notation: HHEAR_259

Annual Income More Than $95,000
type: Class
subclass of: Annual Income More Than $70,001
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 95000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income More Than $95,000
notation: HHEAR_260

Annual Income $85,000 to $94,999
type: Class
subclass of: Annual Income $75,000 to $99,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 94999
subclass of: Restriction
  on property: minValue
  has value: 85000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $85,000 to $94,999
notation: HHEAR_261

Annual Income $75,000 to $84,999
type: Class
subclass of: Annual Income $75,000 to $99,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 84999
subclass of: Restriction
  on property: minValue
  has value: 75000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $75,000 to $84,999
notation: HHEAR_262

Annual Income $65,000 to $74,999
type: Class
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income More Than $65,000
subclass of: Annual Income $60,000 to $74,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 74999
subclass of: Restriction
  on property: minValue
  has value: 65000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $65,000 to $74,999
notation: HHEAR_263

Annual Income $55,000 to $64,999
type: Class
subclass of: Annual Income $50,001 to $75,000
subclass of: Annual Income $50,000 to $74,999
subclass of: Annual Income $45,000 to $64,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 64999
subclass of: Restriction
  on property: minValue
  has value: 55000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $55,000 to $64,999
notation: HHEAR_264

Annual Income $45,000 to $54,999
type: Class
subclass of: Annual Income $45,000 to $64,999
subclass of: Annual Income $40,000 to $60,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 54999
subclass of: Restriction
  on property: minValue
  has value: 45000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $45,000 to $54,999
notation: HHEAR_265

Annual Income $35,000 to $44,999
type: Class
subclass of: Annual Income $35,000 to $49,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 44999
subclass of: Restriction
  on property: minValue
  has value: 35000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $35,000 to $44,999
notation: HHEAR_266

Annual Income $25,000 to $34,999
type: Class
subclass of: Annual Income $20,001 to $40,000
subclass of: Annual Income $25,000 to $49,999
subclass of: Annual Income $25,000 to $50,000
subclass of: Annual Income $39,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 34999
subclass of: Restriction
  on property: minValue
  has value: 25000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $25,000 to $34,999
notation: HHEAR_267

Annual Income $15,000 to $24,999
type: Class
subclass of: Annual Income $15,000 to $29,999
subclass of: Annual Income $24,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 24999
subclass of: Restriction
  on property: minValue
  has value: 15000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $15,000 to $24,999
notation: HHEAR_268

wheezing or tightness in the chest or cough
type: Class
equivalent class: Class
  union of: Cough
  union of: Wheezing
  union of: Chest tightness
subclass of: Phenotypic abnormality
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes wheezing or tightness in the chest or cough

LAC + USC Med Center
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes LAC + USC Med Center
notation: HHEAR_269

Eisner Health
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Eisner Health
notation: HHEAR_270

USC Obstetrics-Gynecology
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes USC Obstetrics-Gynecology
notation: HHEAR_271

Community Recruit
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Community Recruit
notation: HHEAR_272

South Central Clinic
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes South Central Clinic
notation: HHEAR_273

Mean Body Weight
type: Class
subclass of: Physical And Mental Assessment
subclass of: Body Weight Quality
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Mean Body Weight

Mean Height
type: Class
subclass of: SIO_000040
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Mean Height

Asthma Controller Medication
type: Class
subclass of: SIO_010039
definition: A class of pharmeceutical drugs that are used to prevent or manage the onset of acute asthma before an attack occurs.

Asthma Controller Use
type: Class
equivalent class: Class
  union of: Never takes asthma control medications
  union of: Has taken asthma control medications
subclass of: Pharmacotherapy
subclass of: Asthma Controller Medication Prescription
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000230
  some values from: Asthma Controller Medication
subclass of: Restriction
  on property: SIO_000291
  some values from: SIO_000393
type: NamedIndividual
type: Quality Variable
definition: A subclass of medical intervention that characterizes a patient's experience with using an asthma controller medication. Subclasses detail the level to which a patient has used such a medication to control their asthma symptoms, from never used to always uses.

Never takes
type: Class
subclass of: SIO_001289
comment: This class denotes Never takes

Only takes with symptoms
type: Class
subclass of: SIO_001290
comment: This class denotes Only takes with symptoms

Used to take but no longer
type: Class
subclass of: SIO_001288
comment: This class denotes Used to take but no longer

Takes some days but not others
type: Class
subclass of: SIO_001290
comment: This class denotes Takes some days but not others

Takes every day
type: Class
subclass of: SIO_001292
comment: This class denotes Takes every day

Never takes asthma control medications
type: Class
subclass of: Asthma Controller Use
subclass of: Restriction
  on property: SIO_000217
  some values from: Never takes
disjoint with: Has taken asthma control medications
type: NamedIndividual
type: Quality Value
comment: This class denotes Never takes asthma control medications
notation: HHEAR_274

Only takes asthma control medications with symptoms
type: Class
subclass of: Asthma Controller Use
subclass of: Has taken asthma control medications
subclass of: Restriction
  on property: SIO_000217
  some values from: Only takes with symptoms
type: NamedIndividual
type: Quality Value
comment: This class denotes Only takes asthma control medications with symptoms
notation: HHEAR_275

Used to take asthma control medications but no longer
type: Class
subclass of: Asthma Controller Use
subclass of: Has taken asthma control medications
subclass of: Restriction
  on property: SIO_000217
  some values from: Used to take but no longer
type: NamedIndividual
type: Quality Value
comment: This class denotes Used to take asthma control medications but no longer
notation: HHEAR_276

Takes asthma control medications some days but not others
type: Class
subclass of: Asthma Controller Use
subclass of: Has taken asthma control medications
subclass of: Restriction
  on property: SIO_000217
  some values from: Takes some days but not others
type: NamedIndividual
type: Quality Value
comment: This class denotes Takes asthma control medications some days but not others
notation: HHEAR_277

Takes asthma control medications every day
type: Class
subclass of: Asthma Controller Use
subclass of: Has taken asthma control medications
subclass of: Restriction
  on property: SIO_000217
  some values from: Takes every day
type: NamedIndividual
type: Quality Value
comment: This class denotes Takes asthma control medications every day
notation: HHEAR_278

Asthma Induced Reduced Play Or Activity
type: Class
subclass of: behavioral response to pain
subclass of: Lack of spontaneous play
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_001157
  some values from: wheezing or tightness in the chest or cough
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Asthma Induced Reduced Play Or Activity

Asthma Induced Night Sleeplessness
type: Class
subclass of: behavioral response to pain
subclass of: Sleep disturbance
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_001157
  some values from: wheezing or tightness in the chest or cough
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Asthma Induced Night Sleeplessness

Spirometry Outcome
type: Class
subclass of: Respiratory System Findings Original Result
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_001157
  some values from: Spirometry
type: NamedIndividual
type: Quality Variable
comment: This class denotes Spirometry Outcome

Spirometry Outcomes Met Guidelines
type: Class
subclass of: Spirometry Outcome
subclass of: Restriction
  on property: SIO_000217
  some values from: SIO_001312
type: NamedIndividual
type: Quality Value
comment: This class denotes Spirometry Outcomes Met Guidelines
notation: HHEAR_280

Spirometry Outcomes Did Not Meet Guidelines
type: Class
subclass of: Spirometry Outcome
subclass of: Restriction
  on property: SIO_000217
  some values from: SIO_001310
type: NamedIndividual
type: Quality Value
comment: This class denotes Spirometry Outcomes Did Not Meet Guidelines
notation: HHEAR_281

Has taken asthma control medications
type: Class
subclass of: Asthma Controller Use
type: NamedIndividual
type: Quality Value
comment: This class denotes Has taken asthma control medications
notation: HHEAR_282

FVC Percent Predicted Value
type: Class
subclass of: forced vital capacity (FVC)
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000187
type: NamedIndividual
type: Quality Variable
definition: The percent ratio of a patient's best FVC value divided by the expected or predicted FVC value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

FEV1 Percent Predicted Value
type: Class
subclass of: forced expiratory volume
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000187
type: NamedIndividual
type: Quality Variable
definition: The percent ratio of a patient's best FEV1 value divided by the expected or predicted FEV1 value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

FEF 25-75 Percent Predicted Value
type: Class
subclass of: Forced Expiratory Flow at 25-75 Percent
subclass of: Restriction
  on property: hasUnit
  has value: UO_0000187
type: NamedIndividual
type: Quality Variable
definition: The percent ratio of a patient's best FEF 25-75 value divided by the expected or predicted FEF 25-75 value for the patient based on their demographics (typically age, height, sex, and race) and comparison with a population control group.

Childhood Followup 2
type: Class
subclass of: Study Followup 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the initial follow-up point in the study and occurs during the study subject's childhood period.

Asthma Controller Medication Prescription
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: SIO_001398
type: NamedIndividual
type: Quality Variable
definition: A subclass of medical intervention that characterizes a patient's receipt of asthma controller medication by prescription. It does not indicate if a patient has or has not received such medication or a prescription for such medication. These distinctions are made in the subclasses of this class.

Has Received Asthma Controller Medication
type: Class
subclass of: Asthma Controller Medication Prescription
type: NamedIndividual
type: Quality Value
comment: This class denotes Has Received Asthma Controller Medication
notation: HHEAR_283

Monthly Income Less Than $416
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 416
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income Less Than $416
notation: HHEAR_284

Monthly Income $417 to $833
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 833
subclass of: Restriction
  on property: minValue
  has value: 417
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $417 to $833
notation: HHEAR_285

Monthly Income $834 to $1,250
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 1250
subclass of: Restriction
  on property: minValue
  has value: 834
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $834 to $1,250
notation: HHEAR_286

Monthly Income $1,251 to $1,666
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 1666
subclass of: Restriction
  on property: minValue
  has value: 1251
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $1,251 to $1,666
notation: HHEAR_287

Monthly Income $1,667 to $2,083
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 2083
subclass of: Restriction
  on property: minValue
  has value: 1667
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $1,667 to $2,083
notation: HHEAR_288

Monthly Income $2,084 to $2,500
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 2500
subclass of: Restriction
  on property: minValue
  has value: 2084
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $2,084 to $2,500
notation: HHEAR_289

Monthly Income $2,501 to $2,917
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 2917
subclass of: Restriction
  on property: minValue
  has value: 2501
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $2,501 to $2,917
notation: HHEAR_290

Monthly Income $2,918 to $3,333
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 3333
subclass of: Restriction
  on property: minValue
  has value: 2918
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $2,918 to $3,333
notation: HHEAR_291

Monthly Income $3,334 to $3,750
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 3750
subclass of: Restriction
  on property: minValue
  has value: 3334
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $3,334 to $3,750
notation: HHEAR_292

Monthly Income $3,751 to $4,166
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 4166
subclass of: Restriction
  on property: minValue
  has value: 3751
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income $3,751 to $4,166
notation: HHEAR_293

Monthly Income More Than $4,166
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 4166
type: NamedIndividual
type: Quality Value
comment: This class denotes Monthly Income More Than $4,166
notation: HHEAR_294

Asthma Control Test Score
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
definition: The Asthma Control Test is a standardized rating scale developed by Nathan et al in 2004, which is used to identify patients 12 years or older with poorly controlled asthma. This questionnaire contains five items and the score is computed by summing the responses to the five items. The ACT Score range is from 0 to 25, where a higher number indicates a better level of asthma control.

Childhood Asthma Control Test Score
type: Class
subclass of: score
type: NamedIndividual
type: Quantity Variable
definition: The Childhood Asthma Control Test is a standardized rating scale developed by Nathan et al in 2004, which is used to identify patients from 4 to 11 years old with poorly controlled asthma. This questionnaire contains seven items, four to be answered with the child patient and three to be answered by the child patient's guardian and the score is computed by summing the responses to the seven items. The CACT Score range is from 0 to 27, where a higher number indicates a better level of asthma control.

Very Poorly Controlled Asthma
type: Class
subclass of: asthma
subclass of: Health Outcome
subclass of: SIO_001294
type: NamedIndividual
type: Quality Value
comment: This class denotes Very Poorly Controlled Asthma
notation: HHEAR_295

Not Well Controlled Asthma
type: Class
subclass of: asthma
subclass of: Health Outcome
subclass of: SIO_001295
type: NamedIndividual
type: Quality Value
comment: This class denotes Not Well Controlled Asthma
notation: HHEAR_296

Well Controlled Asthma
type: Class
subclass of: asthma
subclass of: Health Outcome
subclass of: SIO_001297
type: NamedIndividual
type: Quality Value
comment: This class denotes Well Controlled Asthma
notation: HHEAR_297

CASI Daytime Asthma Symptoms Score
type: Class
subclass of: Asthma Severity Index Composite Score (CASI)
type: NamedIndividual
type: Quantity Variable
comment: This class denotes CASI Daytime Asthma Symptoms Score

CASI Exacerbation Score
type: Class
subclass of: Asthma Severity Index Composite Score (CASI)
type: NamedIndividual
type: Quantity Variable
comment: This class denotes CASI Exacerbation Score

CASI Lung Function Score
type: Class
subclass of: Asthma Severity Index Composite Score (CASI)
type: NamedIndividual
type: Quantity Variable
comment: This class denotes CASI Lung Function Score

CASI Nighttime Asthma Symptoms Score
type: Class
subclass of: Asthma Severity Index Composite Score (CASI)
type: NamedIndividual
type: Quantity Variable
comment: This class denotes CASI Nighttime Asthma Symptoms Score

CASI Controller Treatment Score
type: Class
subclass of: Asthma Severity Index Composite Score (CASI)
type: NamedIndividual
type: Quantity Variable
comment: This class denotes CASI Controller Treatment Score

Annual Maximum Concentration
type: Class
subclass of: SIO_001088
subclass of: SIO_001114
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Annual Maximum Concentration

Asthma Related Clinic Visit
type: Class
subclass of: Asthma Related Health Encounter
subclass of: Restriction
  on property: SIO_000635
  some values from: asthma
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Asthma Related Clinic Visit

Asthma Related Hospitalization
type: Class
subclass of: Asthma Related Health Encounter
subclass of: Restriction
  on property: SIO_000635
  some values from: asthma
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Asthma Related Hospitalization

Blinded Season 1 Group
type: Class
subclass of: Seasonal Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Blinded Season 1 Group
notation: HHEAR_298

Blinded Season 2 Group
type: Class
subclass of: Seasonal Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Blinded Season 2 Group
notation: HHEAR_299

Blinded Season 3 Group
type: Class
subclass of: Seasonal Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Blinded Season 3 Group
notation: HHEAR_300

Blinded Season 4 Group
type: Class
subclass of: Seasonal Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Blinded Season 4 Group
notation: HHEAR_301

Endotoxin Allergen
type: Class
subclass of: Allergen
comment: This class denotes Endotoxin Allergen

Aspergillus Allergen
type: Class
subclass of: Allergen
comment: This class denotes Aspergillus Allergen

Alternaria Allergen
type: Class
subclass of: Allergen
comment: This class denotes Alternaria Allergen

Cockroach Allergen
type: Class
subclass of: Allergen
comment: This class denotes Cockroach Allergen

Dog Allergen
type: Class
subclass of: Allergen
comment: This class denotes Dog Allergen

Cat Allergen
type: Class
subclass of: Allergen
comment: This class denotes Cat Allergen

Mouse Allergen
type: Class
subclass of: Allergen
comment: This class denotes Mouse Allergen

Bedroom Dust
type: Class
equivalent class: Class
  intersection of: Dust
  intersection of: Restriction
    on property: PATO_0002261
    some values from: http://snomed.info/id/224700005
subclass of: Allergen
comment: This class denotes Bedroom Dust

DERP1 Dust Mite Allergen
type: Class
subclass of: Allergen
comment: This class denotes DERP1 Dust Mite Allergen

DERF1 Dust Mite Allergen
type: Class
subclass of: Allergen
comment: This class denotes DERF1 Dust Mite Allergen

Asthma Diagnosis Group
type: Class
subclass of: Diagnosis Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Asthma Diagnosis Group
notation: HHEAR_312

Bedroom
type: Class
subclass of: room
subclass of: Room
definition: A room in a human dwelling that is the primary location where one or more occupants sleep.

1 or 2 Years of College, Technical, or Vocational Training
type: Class
subclass of: Some College or Technical School
type: NamedIndividual
type: Quality Value
comment: This class denotes 1 or 2 Years of College, Technical, or Vocational Training
notation: HHEAR_313

3 or 4 Years of College, Technical, or Vocational Training
type: Class
subclass of: Some College or Technical School
type: NamedIndividual
type: Quality Value
comment: This class denotes 3 or 4 Years of College, Technical, or Vocational Training
notation: HHEAR_314

5+ Years of College, Technical, or Vocational Training
type: Class
subclass of: Some College or Technical School
type: NamedIndividual
type: Quality Value
comment: This class denotes 5+ Years of College, Technical, or Vocational Training
notation: HHEAR_315

Corticosteroid Burst
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000230
  some values from: corticosteroid
subclass of: Restriction
  on property: SIO_000291
  some values from: SIO_000393
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Corticosteroid Burst

Mean Concentration Range 0 - 10 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 0.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 10.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 0 - 10 ng/mL
notation: HHEAR_316

Mean Concentration Range 10 - 30 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 10.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 30.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 10 - 30 ng/mL
notation: HHEAR_317

Mean Concentration Range 30 - 100 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 30.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 100.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 30 - 100 ng/mL
notation: HHEAR_318

Mean Concentration Range 100 - 200 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 100.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 200.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 100 - 200 ng/mL
notation: HHEAR_319

Mean Concentration Range 200 - 500 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 200.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 500.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 200 - 500 ng/mL
notation: HHEAR_320

Mean Concentration Range 500 - 1000 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 500.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 1000.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range 500 - 1000 ng/mL
notation: HHEAR_321

Mean Concentration Range > 1000 ng/mL
type: Class
subclass of: Mean Concentration
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 1000.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000275
type: NamedIndividual
type: Quality Value
comment: This class denotes Mean Concentration Range > 1000 ng/mL
notation: HHEAR_322

8,12-iso-Isoprostane-F2 alpha-VI
type: Class
subclass of: isoprostane
subclass of: Oxidative Stress Marker
type: NamedIndividual
type: Facet Value
definition: An Isoprostane with the CAS # 1445349-99-4
notation: F2A12I

Seasonal Population Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Variable
definition: A Population Group organized by which season of the year the subjects were tested or studied.

Pregnancy Month 1
type: Class
subclass of: SIO_000417
definition: The first month of pregnancy

Post-Birth 1 Minute
type: Class
subclass of: SIO_000417
definition: One minute after birth of a child

Post-Birth 5 Minutes
type: Class
subclass of: SIO_000417
definition: Five minutes after birth of a child

Non-White Non-Hispanic
type: Class
subclass of: Non-Hispanic Ethnicity
subclass of: Non-White
type: NamedIndividual
type: Quality Value
comment: This class denotes Non-White Non-Hispanic
notation: HHEAR_326

Healthy BMI
type: Class
subclass of: Body Mass Index
subclass of: Health Outcome
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 0.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 25.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000086
type: NamedIndividual
type: Quality Value
comment: This class denotes Healthy BMI
notation: HHEAR_686

Overweight BMI
type: Class
subclass of: Body Mass Index
subclass of: Health Outcome
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 25.0
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 29.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000086
type: NamedIndividual
type: Quality Value
comment: This class denotes Overweight BMI
notation: HHEAR_685

Obese BMI
type: Class
subclass of: Body Mass Index
subclass of: Health Outcome
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 29.0
subclass of: Restriction
  on property: SIO_000221
  has value: UO_0000086
type: NamedIndividual
type: Quality Value
comment: This class denotes Obese BMI
notation: HHEAR_687

Any hypertensive disorder or any diabetes, any BMI
type: Class
equivalent class: Class
  union of: hypertension
  union of: diabetes mellitus
subclass of: Health Outcome
type: NamedIndividual
type: Quality Value
comment: This class denotes Any hypertensive disorder or any diabetes, any BMI
notation: HHEAR_330

Healthy (BMI <25) weight and no hypertensive disorder and no diabetes
type: Class
subclass of: Healthy BMI
subclass of: Class
  intersection of: Healthy BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: NamedIndividual
type: Quality Value
comment: This class denotes Healthy (BMI <25) weight and no hypertensive disorder and no diabetes
notation: HHEAR_327

Overweight (BMI 25-29.9) and no hypertensive disorder and no diabetes
type: Class
subclass of: Overweight BMI
subclass of: Class
  intersection of: Overweight BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: NamedIndividual
type: Quality Value
comment: This class denotes Overweight (BMI 25-29.9) and no hypertensive disorder and no diabetes
notation: HHEAR_328

Obese (BMI >30) and no hypertensive disorder and no diabetes
type: Class
subclass of: Obese BMI
subclass of: Class
  intersection of: Obese BMI
  intersection of: Class
    complement of: Any hypertensive disorder or any diabetes, any BMI
type: NamedIndividual
type: Quality Value
comment: This class denotes Obese (BMI >30) and no hypertensive disorder and no diabetes
notation: HHEAR_329

Uses Cannabinoids
type: Class
subclass of: Cannabis Consumption
subclass of: Restriction
  on property: SIO_000230
  some values from: cannabinoid
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Cannabinoids
notation: HHEAR_692

Pre-Pregnancy and Pregnancy
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: intervalFinishedBy
    some values from: First Trimester
  intersection of: Restriction
    on property: intervalStartedBy
    some values from: Pre-Pregnancy
equivalent class: Class
  intersection of: Restriction
    on property: intervalFinishedBy
    some values from: Pregnancy
  intersection of: Restriction
    on property: intervalStartedBy
    some values from: Pre-Pregnancy
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalFinishedBy
  some values from: Pregnancy
subclass of: Restriction
  on property: intervalStartedBy
  some values from: Pre-Pregnancy
definition: The time period that begins three months prior to conception and ends at the birth of a child.

Childhood Year 1
type: Class
subclass of: SIO_000417
definition: The time period of a child that begins at birth and ends after one year

Childhood Year 2 and Later
type: Class
subclass of: SIO_000417
definition: The time period that begins at the beginning of a child's second year and ends at the end of childhood.

Pre-Pregnancy and Pregnancy Month 1
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalFinishedBy
  some values from: Pregnancy Month 1
subclass of: Restriction
  on property: intervalStartedBy
  some values from: Pre-Pregnancy
definition: The time period that begins three months prior to conception and ends at the end of the first month of pregnancy.

Development Quotient
type: Class
subclass of: Quotient
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
definition: A development quotient is a numerical indicator of a (infant to preschool age) child's growth to maturity across a range of psychosocial competencies.

Mullens Verbal Domain
type: Class
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03173
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03174
type: NamedIndividual
type: Quantity Variable
definition: A composite score derived from the Mullens Receptive Language and Mullens Expressive Language scales.

Mullens Non-Verbal Domain
type: Class
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03171
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03172
type: NamedIndividual
type: Quantity Variable
definition: A composite score derived from the Mullens Visual Reception and Mullens Fine Motor scales..

Vineland Daily Living Skills Domain
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Vineland Daily Living Skills Domain

Vineland Socialization Domain
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Vineland Socialization Domain

Vineland Motor Skills Domain
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Vineland Motor Skills Domain

Vineland Communication Domain
type: Class
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Vineland Communication Domain

Has Used Cannabinoids But No Longer
type: Class
subclass of: Cannabis Consumption
type: NamedIndividual
type: Quality Value
comment: This class denotes Has Used Cannabinoids But No Longer
notation: HHEAR_331

Iron Vitamin Supplement
type: Class
subclass of: Vitamin
subclass of: Restriction
  on property: SIO_000369
  some values from: CHEBI_18248
comment: This class denotes Iron Vitamin Supplement

Uses Iron Supplement
type: Class
subclass of: nutrition intake
subclass of: Restriction
  on property: SIO_000139
  some values from: Iron Vitamin Supplement
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Iron Supplement
notation: HHEAR_332

Folic Acid Vitamin Supplement
type: Class
subclass of: Vitamin
subclass of: Restriction
  on property: SIO_000369
  some values from: folic acid
comment: This class denotes Folic Acid Vitamin Supplement

Uses Folic Acid Supplement
type: Class
subclass of: nutrition intake
subclass of: Restriction
  on property: SIO_000139
  some values from: Folic Acid Vitamin Supplement
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Folic Acid Supplement
notation: HHEAR_333

B6 Vitamin Supplement
type: Class
subclass of: Vitamin B6 or Vitamin B7 or B Complex Vitamin Supplement
subclass of: Restriction
  on property: SIO_000369
  some values from: vitamin B6
type: NamedIndividual
type: Quality Value
comment: This class denotes B6 Vitamin Supplement
notation: HHEAR_1209

Uses B6 Supplement
type: Class
subclass of: nutrition intake
subclass of: Restriction
  on property: SIO_000139
  some values from: B6 Vitamin Supplement
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses B6 Supplement
notation: HHEAR_334

Average Iron Supplement Intake
type: Class
subclass of: Uses Iron Supplement
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Average Iron Supplement Intake

Average Folic Acid Supplement Intake
type: Class
subclass of: Uses Folic Acid Supplement
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Average Folic Acid Supplement Intake

Average B6 Supplement Intake
type: Class
subclass of: Uses B6 Supplement
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Average B6 Supplement Intake

Pregnancy Month 6
type: Class
subclass of: SIO_000417
definition: The sixth month of pregnancy

Public or No Insurance
type: Class
equivalent class: Class
  union of: Public Insurance
  union of: No Insurance / Self-funded
subclass of: Insurance
type: NamedIndividual
type: Quality Value
comment: This class denotes Public or No Insurance
notation: HHEAR_335

Alta, Far Northern, and Redwood Coast
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Alta, Far Northern, and Redwood Coast
notation: HHEAR_336

North Bay
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes North Bay
notation: HHEAR_337

East Bay, San Andreas, and Golden Gate
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes East Bay, San Andreas, and Golden Gate
notation: HHEAR_338

Valley Mt, Central Valley, and Kern
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes Valley Mt, Central Valley, and Kern
notation: HHEAR_339

All Los Angeles RCs plus Orange, San Diego, Tri-counties, and Inland
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
comment: This class denotes All Los Angeles RCs plus Orange, San Diego, Tri-counties, and Inland
notation: HHEAR_340

Daily Living Skills Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: Vineland Daily Living Skills Domain
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Daily Living Skills Developmental Quotient

Socialization Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: Vineland Socialization Domain
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Socialization Developmental Quotient

Motor Skills Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: Vineland Motor Skills Domain
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Motor Skills Developmental Quotient

Communication Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: Vineland Communication Domain
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Communication Developmental Quotient

Receptive Language Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03174
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Receptive Language Developmental Quotient

Expressive Language Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03173
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Expressive Language Developmental Quotient

Visual Reception Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03171
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Visual Reception Developmental Quotient

Fine Motor Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_03172
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Fine Motor Developmental Quotient

Early Learning Developmental Quotient
type: Class
subclass of: Development Quotient
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: CAO_01393
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Early Learning Developmental Quotient

Month Prior and First Month of Pregnancy
type: Class
subclass of: SIO_000417
definition: The time period beginning at the beginning of the month prior to conception and ending at the end of the first month of pregnancy

Early Concerns or High Risk for Autism
type: Class
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Early Concerns or High Risk for Autism
notation: HHEAR_343

Vineland Testing
type: Class
subclass of: Childhood Followup
subclass of: Restriction
  on property: SIO_000668
  some values from: Class
    intersection of: Childhood Period
definition: The time period when the Vineland early childhood development testing is administered to a subject.

Mullens Testing
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Childhood Period
definition: The time period when the Mullens early childhood development testing is administered to a subject.

Received Antimalarial Therapy
type: Class
subclass of: Received Drug Therapy
subclass of: Antimalarial Use
subclass of: Restriction
  on property: SIO_000230
  some values from: Antimalarial
type: NamedIndividual
type: Quality Value
comment: This class denotes Received Antimalarial Therapy
notation: HHEAR_344

Received Drug Therapy Other Than Antimalarials
type: Class
subclass of: Received Drug Therapy
subclass of: Drug Other Than Antimalarial Use
subclass of: Restriction
  on property: SIO_000230
  some values from: drug other than antimalarial
type: NamedIndividual
type: Quality Value
comment: This class denotes Received Drug Therapy Other Than Antimalarials
notation: HHEAR_345

drug other than antimalarial
type: Class
subclass of: drug
subclass of: Class
  intersection of: drug
  intersection of: Class
    complement of: Antimalarial
definition: Any drug other than an antimalarial drug

Received Drug Therapy
type: Class
subclass of: Pharmacotherapy
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000230
  some values from: drug
comment: This class denotes Received Drug Therapy
notation: HHEAR_360

Hemoglobin Genotype AA
type: Class
subclass of: SCD Genotype
subclass of: SIO_001079
subclass of: Restriction
  on property: SCDO_1000222
  some values from: SCDO_0004139
disjoint with: Restriction
  on property: SCDO_1000222
  some values from: SCDO_0000514
type: NamedIndividual
type: Quality Value
IAO_0000115: A genotype whereby both HBB alleles produce hemoglobin beta chains for normal adult hemoglobin. Individuals with this genotype are not carriers of the sickle cell trait.
has exact synonym: AA Genotype
has exact synonym: AA Hemoglobin Genotype
has exact synonym: Haemoglobin Genotype AA
has exact synonym: Hemoglobin A Genotype
comment: This class denotes Hemoglobin Genotype AA
notation: HHEAR_348

Annual Income $30,000 to $60,000
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 60000
subclass of: Restriction
  on property: minValue
  has value: 30000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $30,000 to $60,000
notation: HHEAR_349

Annual Income More Than $60,000
type: Class
subclass of: Annual Income More Than $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 60000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income More Than $60,000
notation: HHEAR_350

First Void Urination
type: Class
subclass of: Urination
type: NamedIndividual
type: Quality Value
comment: This class denotes First Void Urination
notation: HHEAR_356

First Void Urine
type: Class
subclass of: urine
subclass of: Restriction
  on property: SIO_000311
  some values from: First Void Urination
type: NamedIndividual
type: Quality Value
comment: This class denotes First Void Urine
notation: HHEAR_357

Antimalarial Use
type: Class
subclass of: Pharmacotherapy
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000230
  some values from: Antimalarial
subclass of: Restriction
  on property: SIO_000291
  some values from: SIO_000393
definition: A subclass of medical intervention that characterizes a patient's experience with using an antimalarial. Subclasses detail the level to which a patient has used such a medication to prevent or treat malaria.

Drug Other Than Antimalarial Use
type: Class
subclass of: Pharmacotherapy
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000230
  some values from: drug other than antimalarial
subclass of: Restriction
  on property: SIO_000291
  some values from: SIO_000393
comment: This class denotes Drug Other Than Antimalarial Use

Allergy Test
type: Class
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000563
  some values from: Allergy
type: NamedIndividual
type: Quality Variable
comment: This class denotes Allergy Test

Valid Test
type: Class
subclass of: Test
disjoint with: Invalid Test
comment: This class denotes Valid Test

Invalid Test
type: Class
subclass of: Test
comment: This class denotes Invalid Test

Valid Allergy Test
type: Class
equivalent class: Class
  intersection of: Allergy Test
  intersection of: Valid Test
subclass of: Allergy Test
subclass of: Valid Test
type: NamedIndividual
type: Quality Value
comment: This class denotes Valid Allergy Test
notation: HHEAR_359

Invalid Allergy Test
type: Class
equivalent class: Class
  intersection of: Allergy Test
  intersection of: Invalid Test
subclass of: Allergy Test
subclass of: Invalid Test
type: NamedIndividual
type: Quality Value
comment: This class denotes Invalid Allergy Test
notation: HHEAR_358

admission diagnosis
type: Class
subclass of: Health Outcome
subclass of: SIO_001331
subclass of: Restriction
  on property: SIO_000687
  some values from: Admission
comment: A medical diagnosis that occurs at admission to a hospital or other medical care provider.

Hospital Admission
type: Class
subclass of: Hospitalization
subclass of: Medical History
subclass of: Healthcare Facility Admission
subclass of: Restriction
  on property: SIO_000061
  some values from: Hospital
comment: The event of admitting some patient into a hospital.

Hospital Readmission
type: Class
subclass of: Hospital Admission
subclass of: Restriction
  on property: SIO_000249
  some values from: Hospital Discharge
comment: The event of re-admitting some patient into a hospital after they had previously been discharged.

ICU Admission
type: Class
subclass of: Healthcare Facility Admission
subclass of: Restriction
  on property: SIO_000061
  some values from: Intensive Care Unit
comment: The event of admitting some patient into the ICU.

ICU Readmission
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Restriction
    on property: SIO_000249
    some values from: ICU Discharge
subclass of: ICU Admission By Re-admission Status
subclass of: Restriction
  on property: SIO_000249
  some values from: ICU Discharge
disjoint with: ICU First Admission
type: NamedIndividual
type: Quality Value
comment: The event of re-admitting some patient into an ICU after they had previously been discharged.
notation: HHEAR_373

Healthcare Facility Admission
type: Class
subclass of: Healthcare Access
subclass of: Activity
subclass of: Restriction
  on property: SIO_000061
  some values from: Healthcare Facility
subclass of: Restriction
  on property: SIO_000132
  some values from: SIO_000393
comment: An event in which a patient is admitted into a healthcare facility.

Medical Discharge
type: Class
subclass of: Activity
comment: An event in which a person is discharged from a medical facility.

Hospital Discharge
type: Class
subclass of: Healthcare Access
subclass of: Medical History
subclass of: Medical Discharge
subclass of: Restriction
  on property: SIO_000249
  some values from: Hospital Admission
type: NamedIndividual
type: Quality Variable
comment: An event in which a person is discharged from a hospital.

ICU Discharge
type: Class
subclass of: Healthcare Access
subclass of: Medical History
subclass of: Medical Discharge
subclass of: Restriction
  on property: SIO_000249
  some values from: ICU Admission
type: NamedIndividual
type: Quality Variable
comment: An event in which a person is discharged from an intensive care unit.

ICU Discharge On Oxygen
type: Class
equivalent class: Class
  intersection of: ICU Discharge
  intersection of: Restriction
    on property: SIO_000250
    some values from: Oxygen Treatment
subclass of: ICU Discharge By Oxygen Use
subclass of: Restriction
  on property: SIO_000250
  some values from: Oxygen Treatment
disjoint with: ICU Discharge Not On Oxygen
type: NamedIndividual
type: Quality Value
comment: An event in which a patient is discharged from an intensive care unit and is given oxygen treatment.
notation: HHEAR_372

Hospital Discharge On Oxygen
type: Class
equivalent class: Class
  intersection of: Hospital Discharge
  intersection of: Restriction
    on property: SIO_000250
    some values from: Oxygen Treatment
subclass of: Hospital Discharge By Oxygen Use
subclass of: Restriction
  on property: SIO_000250
  some values from: Oxygen Treatment
disjoint with: Hospital Discharge Not On Oxygen
type: NamedIndividual
type: Quality Value
comment: An event in which a patient is discharged from a hospital and is given oxygen treatment.
notation: HHEAR_370

Oxygen Treatment
type: Class
subclass of: Home Medical Technology
subclass of: SIO_001398
subclass of: Restriction
  on property: SIO_000139
  some values from: SIO_011007
comment: A medical intervention in which a patient is treated with oxygen.

Uses Muscle Relaxants
type: Class
subclass of: Pharmacotherapy
subclass of: Restriction
  on property: SIO_000139
  some values from: muscle relaxant
type: NamedIndividual
type: Quality Value
definition: Had a form of treatment which uses muscle relaxants.
notation: HHEAR_688

Uses Antibiotics
type: Class
subclass of: Pharmacotherapy
subclass of: Restriction
  on property: SIO_000139
  some values from: CHEBI_33281
disjoint with: Does Not Use Antibiotics
type: NamedIndividual
type: Quality Value
definition: Had a form of treatment which uses antibiotics.
notation: HHEAR_379

ICU Admission Requiring Tracheostomy
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Restriction
    on property: SIO_000250
    some values from: tracheostomy
subclass of: ICU Admission By Tracheostomy Status
subclass of: Restriction
  on property: SIO_000250
  some values from: tracheostomy
type: NamedIndividual
type: Quality Value
comment: An ICU Admission of a patient that requires a tracheostomy immediately upon admission.
notation: HHEAR_377

Chest Tube Placement
type: Class
subclass of: SIO_001024
subclass of: Restriction
  on property: SIO_000139
  some values from: Chest Tube
comment: This class denotes Chest Tube Placement

catheterization associated UTI
type: Class
subclass of: urinary tract infection
subclass of: hospital-acquired infection
subclass of: CAUTI or CLABSI or VAP
subclass of: Restriction
  on property: SIO_001157
  some values from: Catheterization
comment: This class denotes catheterization associated UTI

CAUTI or CLABSI or VAP
type: Class
equivalent class: Class
  union of: Central Line Infection
  union of: catheterization associated UTI
  union of: EFO_1001865
subclass of: hospital-acquired infection
type: NamedIndividual
type: Quality Value
comment: This class denotes CAUTI or CLABSI or VAP
notation: HHEAR_362

Pediatric Cerebral Performance Category
type: Class
subclass of: Physical And Mental Assessment
comment: Reference: POPC/PCPC Reference: Fiser HD, Tilford JM, Roberson PK. Relationship of illness severity and length of stay to functional outcomes in the pediatric intensive care unit. Critical Care Medicine 2000. 28(4):1173-1179.

Pediatric Overall Performance Category
type: Class
subclass of: Physical And Mental Assessment
comment: Reference: POPC/PCPC Reference: Fiser HD, Tilford JM, Roberson PK. Relationship of illness severity and length of stay to functional outcomes in the pediatric intensive care unit. Critical Care Medicine 2000. 28(4):1173-1179.

Difference of PCPC Scores
type: Class
subclass of: Difference
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Subtrahend
    intersection of: Pediatric Cerebral Performance Category
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Minuend
    intersection of: Pediatric Cerebral Performance Category
type: NamedIndividual
type: Quantity Variable
comment: The arithemetic difference of two Pediatric Cerebral Performance Category scores.

Difference of POPC Scores
type: Class
subclass of: Difference
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Subtrahend
    intersection of: Pediatric Overall Performance Category
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: Minuend
    intersection of: Pediatric Overall Performance Category
type: NamedIndividual
type: Quantity Variable
comment: The arithemetic difference of two Pediatric Overall Performance Category scores.

Ventilator Free Respiration
type: Class
equivalent class: Class
  intersection of: respiration
  intersection of: Class
    complement of: Restriction
      on property: SIO_001157
      some values from: EFO_0010720
subclass of: respiration
disjoint with: Invasive Mechanical Ventilator Assisted Respiration
comment: Resipration that is not aided by a mechanical ventilator.

Pediatric Intensive Care Unit
type: Class
subclass of: Intensive Care Unit
type: NamedIndividual
type: Quality Value
comment: This class denotes Pediatric Intensive Care Unit
notation: HHEAR_689

microbiome richness
type: Class
subclass of: community species diversity
subclass of: Physical And Mental Assessment
subclass of: Health Outcome
subclass of: SIO_000052
type: NamedIndividual
type: Quantity Variable
comment: Microbiome richness is the total number of bacterial species in a microbiome.

Hospital ER Admission
type: Class
subclass of: Hospital Admission
subclass of: Restriction
  on property: SIO_000061
  some values from: Hospital Emergency Room
type: NamedIndividual
type: Quality Value
comment: This class denotes an ER admission that results in a hospital admission as well.
notation: HHEAR_371

Hospital Emergency Room
type: Class
subclass of: Emergency Medical Services Facility
subclass of: Restriction
  on property: SIO_000061
  some values from: Hospital
comment: This class denotes Hospital Emergency Room

Trauma Related Hospital Admission
type: Class
subclass of: Hospital Admission By Admission Type
subclass of: Restriction
  on property: SIO_001157
  some values from: EFO_0000546
type: NamedIndividual
type: Quality Value
comment: This class denotes Trauma Related Hospital Admission
notation: HHEAR_378

Surgery Related Hospital Admission
type: Class
subclass of: Hospital Admission By Admission Type
subclass of: Restriction
  on property: SIO_000243
  some values from: surgical procedure
type: NamedIndividual
type: Quality Value
comment: This class denotes Surgery Related Hospital Admission
notation: HHEAR_376

Medical Related Hospital Admission
type: Class
subclass of: Hospital Admission By Admission Type
type: NamedIndividual
type: Quality Value
comment: This class denotes Medical Related Hospital Admission
notation: HHEAR_375

Nitric Oxide Ventilation
type: Class
subclass of: artificial respiration
subclass of: ventilator supporting therapy
subclass of: Restriction
  on property: SIO_000139
  some values from: Nitric Oxide
comment: The administration of nitric oxide gas via artificial ventilation mechanisms.

ventilator supporting therapy
type: Class
subclass of: SIO_001398
type: NamedIndividual
type: Quality Value
comment: Medical procedures that support life systems when a patient is receiving invasive ventilation treatments.
notation: HHEAR_383

Functional Status Score
type: Class
subclass of: score
comment: Functional Status Score (FSS) includes six domains with a scale from 1-5 with one being normal and 5 being very severely dysfunctional. A change would represent a new morbidity for the patient after ICU admission.1 (normal) to 6 (severely dysfunctional). FSS Score Reference: Pollack, M et al. The functional status score (FSS): a new pediatric outcome measure. Pediatrics, 2009. 124(1):18-28.

Functional Status Mental Status Score
type: Class
subclass of: Functional Status Score
comment: This class denotes Functional Status Mental Status Score

Functional Status Sensory Functioning Score
type: Class
subclass of: Functional Status Score
comment: This class denotes Functional Status Sensory Functioning Score

Functional Status Communication Score
type: Class
subclass of: Functional Status Score
comment: This class denotes Functional Status Communication Score

Functional Status Motor Functioning Score
type: Class
subclass of: Functional Status Score
comment: This class denotes Functional Status Motor Functioning Score

Functional Status Feeding Score
type: Class
subclass of: Functional Status Score
comment: This class denotes Functional Status Feeding Score

Functional Status Respiratory Status Score
type: Class
subclass of: Physical And Mental Assessment
subclass of: Functional Status Score
comment: This class denotes Functional Status Respiratory Status Score

Functional Status Total Score
type: Class
subclass of: Physical And Mental Assessment
subclass of: Functional Status Score
comment: This class denotes Functional Status Total Score

Functional Status Total Score 3 or Above
type: Class
subclass of: Functional Status Total Score
type: NamedIndividual
type: Quality Value
comment: This class denotes Functional Status Total Score 3 or Above
notation: HHEAR_368

Functional Status Total Score Below 3
type: Class
subclass of: Functional Status Total Score
type: NamedIndividual
type: Quality Value
comment: This class denotes Functional Status Total Score Below 3
notation: HHEAR_369

Functional Status Respiratory Status Score 2 or Above
type: Class
subclass of: Functional Status Respiratory Status Score
type: NamedIndividual
type: Quality Value
comment: This class denotes Functional Status Respiratory Status Score 2 or Above
notation: HHEAR_366

Functional Status Respiratory Status Score Below 2
type: Class
subclass of: Functional Status Respiratory Status Score
type: NamedIndividual
type: Quality Value
comment: This class denotes Functional Status Respiratory Status Score Below 2
notation: HHEAR_367

Comorbidity Disease
type: Class
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Comorbidity Disease
notation: HHEAR_363

Antibiotic Score
type: Class
subclass of: score
subclass of: Prescription Medication and Dietary Supplements
comment: Antibiotic Score is the total coverage score that was based on whether the antibiotic included coverage against gram-positive bacteria, gram-negative bacteria and/or anaerobic bacteria. Coverage in each area was graded on a 3-point scale: 0 for no activity, 1 for narrow activity, and 2 for broad activity. For patients treated with multiple antibiotics simultaneously, the score for each antibiotic received on a given day was summed. Cumulative scores were summed across days.

duration hospital admission to urine sample
type: Class
subclass of: duration
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
comment: This class denotes duration hospital admission to urine sample

Pediatric Risk of Mortality Score (PRISM III)
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
comment: "The PRISM III score has 17 physiologic variables subdivided into 26 ranges. The variables most predictive of mortality were minimum systolic blood pressure, abnormal pupillary reflexes, and stupor/coma. Other risk factors, including two acute and two chronic diagnoses, and four additional risk factors, were used in the final predictors." (See skos:editorialNote for reference)
editorial note: This concept is taken from PRISM III: an updated Pediatric Risk of Mortality score M M Pollack 1, K M Patel, U E Ruttimann PMID: 8706448 DOI: 10.1097/00003246-199605000-00004 https://pubmed.ncbi.nlm.nih.gov/8706448/

Home Ventilation
type: Class
subclass of: artificial respiration
subclass of: Home Medical Technology
subclass of: Restriction
  on property: SIO_000061
  some values from: Home
comment: This class denotes Home Ventilation

Home Medical Technology
type: Class
subclass of: SIO_001398
type: NamedIndividual
type: Quality Value
comment: This class denotes Home Medical Technology
notation: HHEAR_364

Post Ventilation Childhood Followup
type: Class
subclass of: Childhood Followup
comment: A follow-up evaluation that occurs after the subject has been removed from artificial ventilation.

Post Ventilation Childhood Followup 2
type: Class
subclass of: Childhood Followup 2
comment: A second follow-up evaluation that occurs after the subject has been removed from artificial ventilation.

Cardiovascular disease - acquired
type: Class
subclass of: arteriosclerotic cardiovascular disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Cardiovascular disease - acquired
notation: HHEAR_388

Cardiovascular disease - congenital
type: Class
subclass of: arteriosclerotic cardiovascular disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Cardiovascular disease - congenital
notation: HHEAR_389

Congenital anomaly or chromosomal defect
type: Class
equivalent class: Class
  union of: Congenital Abnormality
  union of: EFO_0000336
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Congenital anomaly or chromosomal defect
notation: HHEAR_390

Drowning
type: Class
subclass of: Drowning or Asphyxia or Hanging
subclass of: Activity
comment: Drowning is a type of suffocation induced by the submersion or immersion of the mouth and nose in a liquid. ... An incident of drowning can also cause further complications for victims due to low body temperature, aspiration of vomit, or acute respiratory distress syndrome (respiratory failure from lung inflammation). (Source: https://en.wikipedia.org/wiki/Drowning)

Hanging
type: Class
subclass of: Drowning or Asphyxia or Hanging
subclass of: Activity
comment: Hanging is the suspension of a person by a noose or ligature around the neck. ... Hanging is a common method of suicide in which a person applies a ligature to the neck and brings about unconsciousness and then death by suspension or partial suspension. (Source: https://en.wikipedia.org/wiki/Hanging).

Drowning or Asphyxia or Hanging
type: Class
equivalent class: Class
  union of: Drowning
  union of: Hanging
  union of: EFO_0009446
subclass of: Activity
type: NamedIndividual
type: Quality Value
comment: This class denotes Drowning or Asphyxia or Hanging
notation: HHEAR_393

Drug Ingestion
type: Class
subclass of: ingestion
subclass of: Drug or Toxin Ingestion
subclass of: Restriction
  on property: SIO_000139
  some values from: drug
comment: This class denotes Drug Ingestion

Toxin Ingestion
type: Class
subclass of: ingestion
subclass of: Drug or Toxin Ingestion
subclass of: Restriction
  on property: SIO_000139
  some values from: toxin
comment: This class denotes Toxin Ingestion

Drug or Toxin Ingestion
type: Class
equivalent class: Class
  union of: Drug Ingestion
  union of: Toxin Ingestion
subclass of: ingestion
type: NamedIndividual
type: Quality Value
comment: This class denotes Drug or Toxin Ingestion
notation: HHEAR_394

Neurological Vascular Malformation
type: Class
subclass of: Neurologic
subclass of: EFO_0006888
type: NamedIndividual
type: Quality Value
comment: Vascular malformations within the central nervous system
editorial note: Additional research I did suggests this CNS vascular malformations includes AVMs, capillary telangiectasias, cavernous malformations, dural arteriovenous fistulas, venous malformations.
notation: HHEAR_411

Non-infectious Respiratory Distress
type: Class
equivalent class: Class
  intersection of: Respiratory distress
  intersection of: Class
    complement of: Restriction
      on property: SIO_001157
      some values from: Infectious Disorder
subclass of: Respiratory distress
type: NamedIndividual
type: Quality Value
comment: This class denotes Non-infectious Respiratory Distress
notation: HHEAR_397

Rheumatology disorder (SLE, Wegeners, JRA)
type: Class
equivalent class: Class
  union of: granulomatosis with polyangiitis
  union of: juvenile rheumatoid arthritis
  union of: systemic lupus erythematosus
subclass of: Disease
type: NamedIndividual
type: Quality Value
comment: This class denotes Rheumatology disorder (SLE, Wegeners, JRA)
notation: HHEAR_398

Sepsis, Septic Shock, or SIRS
type: Class
equivalent class: Class
  union of: Sepsis
  union of: Systemic Inflammatory Response Syndrome
  union of: septic shock
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Sepsis, Septic Shock, or SIRS
notation: HHEAR_399

Stroke, Cerebral Ischemia, or Cerebral infarction
type: Class
equivalent class: Class
  union of: brain ischemia
  union of: cerebral infarction
  union of: stroke
subclass of: SIO_010056
type: NamedIndividual
type: Quality Value
comment: This class denotes Stroke, Cerebral Ischemia, or Cerebral infarction
notation: HHEAR_400

Spinal Surgery
type: Class
subclass of: surgical procedure
subclass of: Scoliosis or Spinal Surgery
subclass of: Restriction
  on property: SIO_000230
  some values from: spinal cord
type: NamedIndividual
type: Quality Variable
comment: This class denotes Spinal Surgery

Scoliosis or Spinal Surgery
type: Class
equivalent class: Class
  union of: scoliosis
  union of: Spinal Surgery
subclass of: Thing
type: NamedIndividual
type: Quality Value
comment: This class denotes Scoliosis or Spinal Surgery
notation: HHEAR_443

Three Months Prior to Pregnancy
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: A subclass of Pre-pregnancy; the three months immediately prior to conception.

Second Hand Smoke Exposure by Frequency
type: Class
subclass of: EFO_0008361
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes second hand smoke exposure by frequency
notation: HHEAR_408

Frequently exposed to second hand smoke
type: Class
subclass of: Second Hand Smoke Exposure by Frequency
subclass of: Has Been Exposed to Second Hand Smoke
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Frequently exposed to second hand smoke
notation: HHEAR_407

Number of Smokers in Household
type: Class
subclass of: Alcohol, Tobacco, and Illicit Drug Use
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Household
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The number of smokers who live in a household

Prenatal Period
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: The time period prior to birth.

Postnatal Period
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: The time period after birth.

e-cigarette behavior
type: Class
subclass of: Consumption Behavior
type: NamedIndividual
type: NodeShape
comment: Inhaling and exhaling the vapors produced by electronic cigarette, or "vaping" devices.

Neurological Issues with Spinal Cord
type: Class
subclass of: Neurologic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: These would include spinal cord and spine injuries our conditions.
notation: HHEAR_409

Neurological Issues with Cerebral Spinal Fluid
type: Class
subclass of: Neurologic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Conditions that cause obstruction to cerebral spinal fluid flow or absorption
notation: HHEAR_410

Neurological Issues from Infectious Causes of Airway Obstruction
type: Class
subclass of: Neurologic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Infectious conditions that cause airway obstruction, e.g. Croup
notation: HHEAR_412

Neurological Issues from Non-infectious Causes of Airway Obstruction
type: Class
subclass of: Neurologic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Non-infectious (mostly congenital or cancer) causes for airway obstruction
notation: HHEAR_413

environmental tobacco smoke exposure frequency
type: Class
subclass of: SIO_001367
subclass of: EFO_0008361
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The frequency at which a subject is exposed to second hand tobacco smoke; measured in days per week, hours per day, etc.

Study Location
type: Class
subclass of: Location
subclass of: Restriction
  on property: SIO_000145
  some values from: Study
type: NamedIndividual
type: NodeShape
comment: The location where a clinical study is conducted; this could be a hospital, medical school, university, or other research institution.

Study Hospital
type: Class
subclass of: Hospital
subclass of: Study Location
type: NamedIndividual
type: NodeShape
comment: The hospital at which a study is conducted

Hospital Admission From Study Emergency Department
type: Class
subclass of: Hospital Admission By Admission Source
disjoint with: Hospital Admission Not From Study Emergency Department
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An admission from an emergency department into a hospital where a clinical study is being conducted, and the subject admitted is participating in the study.
notation: HHEAR_435

Study Emergency Department
type: Class
subclass of: Emergency Medical Services Facility
subclass of: Study Location
type: NamedIndividual
type: NodeShape
comment: An emergency department in a hospital at which a study is being conducted

Annual Income $4,999 or Less
type: Class
subclass of: Annual Income $5,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 4999
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $4,999 or Less
notation: HHEAR_414

Annual Income $5,000 to $9,999
type: Class
subclass of: Annual Income $10,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 9999
subclass of: Restriction
  on property: minValue
  has value: 5000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $5,000 to $9,999
notation: HHEAR_415

Annual Income $10,000 to $19,999
type: Class
subclass of: Annual Income $20,000 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 19999
subclass of: Restriction
  on property: minValue
  has value: 10000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $10,000 to $19,999
notation: HHEAR_416

Annual Income $20,000 to $29,999
type: Class
subclass of: Annual Income $15,001 to $30,000
subclass of: Annual Income $15,000 to $29,999
subclass of: Annual Income $20,000 to $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 29999
subclass of: Restriction
  on property: minValue
  has value: 20000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $20,000 to $29,999
notation: HHEAR_417

Annual Income $30,000 to $39,999
type: Class
subclass of: Annual Income $20,001 to $40,000
subclass of: Annual Income $30,000 to $49,999
subclass of: Annual Income $39,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 39999
subclass of: Restriction
  on property: minValue
  has value: 30000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $30,000 to $39,999
notation: HHEAR_418

Annual Income $40,000 to $49,999
type: Class
subclass of: Annual Income $35,000 to $49,999
subclass of: Annual Income $40,000 to $60,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 49999
subclass of: Restriction
  on property: minValue
  has value: 40000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $40,000 to $49,999
notation: HHEAR_419

Annual Income $50,000 to $74,999
type: Class
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income $40,000 to $74,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 74999
subclass of: Restriction
  on property: minValue
  has value: 50000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $50,000 to $74,999
notation: HHEAR_420

Annual Income $75,000 to $99,999
type: Class
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income $75,000 to $149,999
subclass of: Annual Income $60,000 to $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 99999
subclass of: Restriction
  on property: minValue
  has value: 75000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $75,000 to $99,999
notation: HHEAR_421

Annual Income $100,000 to $199,999
type: Class
subclass of: Annual Income More Than $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 199999
subclass of: Restriction
  on property: minValue
  has value: 100000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $100,000 to $199,999
notation: HHEAR_422

Annual Income More Than $200,000
type: Class
subclass of: Annual Income More Than $125,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 200000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income More Than $200,000
notation: HHEAR_423

Mean Circumference
type: Class
subclass of: SIO_000047
subclass of: SIO_001109
type: NamedIndividual
type: NodeShape
comment: The mean value obtained from several measurements of an object's circumference

Developmental delay or intellectual disability
type: Class
equivalent class: Class
  union of: Intellectual disability
  union of: Neurodevelopmental delay
subclass of: Neurodevelopmental abnormality
type: NamedIndividual
type: Quality Value
comment: This class denotes Developmental delay or intellectual disability
notation: HHEAR_427

Sneezing, Runny Nose, or Congestion
type: Class
equivalent class: Class
  union of: Nasal congestion
  union of: Sneeze
  union of: Rhinorrhea
subclass of: SIO_010056
type: NamedIndividual
type: NodeShape
comment: This class denotes Sneezing, Runny Nose, or Congestion
notation: HHEAR_428

Food Product Packaged in Plastic
type: Class
equivalent class: Class
  intersection of: food product
  intersection of: Restriction
    on property: SIO_000128
    some values from: metal container
equivalent class: Class
  intersection of: food product
  intersection of: Restriction
    on property: SIO_000128
    some values from: plastic container
subclass of: food product
subclass of: Restriction
  on property: SIO_000128
  some values from: plastic container
type: NamedIndividual
type: NodeShape
comment: This class denotes Food Product Packaged in Plastic

Eats Food Packaged in Plastic
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000230
  some values from: Food Product Packaged in Plastic
type: NamedIndividual
type: NodeShape
comment: The act of eating food that has been packaged in a plastic container.

Beverage Packaged in Plastic
type: Class
equivalent class: Class
  intersection of: beverage
  intersection of: Restriction
    on property: SIO_000128
    some values from: plastic container
subclass of: beverage
subclass of: Restriction
  on property: SIO_000128
  some values from: plastic container
type: NamedIndividual
type: NodeShape
comment: A liquid beverage that is packaged in a plastic container

Drinks Beverage Packaged in Plastic
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000230
  some values from: Beverage Packaged in Plastic
type: NamedIndividual
type: NodeShape
comment: The act of drinking a beverage that has been packaged in a plastic container.

Food Or Beverage Product Reheated in a Plastic Container
type: Class
subclass of: food product
subclass of: Restriction
  on property: SIO_000311
  some values from: Reheating Food or Beverage in a Plastic Container
type: NamedIndividual
type: NodeShape
comment: Food (or beverage) that has been reheated inside a container made of plastic

Consumes Food Or Beverage Reheated in Plastic
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000230
  some values from: Food Or Beverage Product Reheated in a Plastic Container
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of consuming food (or beverages) that have been reheated in a plastic container.
notation: HHEAR_565

Uses Plastic Containers for Food Or Beverage Storage
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000230
  some values from: plastic container
type: NamedIndividual
type: NodeShape
comment: The act of using plastic containers to store food or beverages.

BPA Free Plastic Container
type: Class
equivalent class: Class
  intersection of: plastic container
  intersection of: Class
    complement of: Restriction
      on property: SIO_000369
      some values from: Bisphenol A
subclass of: plastic container
subclass of: Class
  complement of: Restriction
    on property: SIO_000369
    some values from: Bisphenol A
type: NamedIndividual
type: NodeShape
comment: A plastic container that does not contain BPA (Bisphenol A).

Uses BPA Free Plastic Containers for Food Or Beverage Storage
type: Class
subclass of: Uses Plastic Containers for Food Or Beverage Storage
subclass of: Restriction
  on property: SIO_000230
  some values from: BPA Free Plastic Container
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of using BPA free plastic containers to store food or beverages.
notation: HHEAR_594

Canned Food Product
type: Class
equivalent class: Class
  intersection of: food product
  intersection of: Restriction
    on property: SIO_000128
    some values from: metal container
subclass of: food product
subclass of: Restriction
  on property: SIO_000128
  some values from: metal container
type: NamedIndividual
type: NodeShape
comment: This class denotes Canned Food Product

Eats School Lunch
type: Class
subclass of: Diet and Nutrition
subclass of: Eating or Drinking
subclass of: Restriction
  on property: SIO_000230
  some values from: School Lunch
type: NamedIndividual
type: NodeShape
comment: The act of eating a school prepared lunch.

School Breakfast
type: Class
subclass of: Breakfast
subclass of: Restriction
  on property: SIO_000061
  some values from: school
type: NamedIndividual
type: NodeShape
comment: Breakfast meal prepared by, and served at school.

School Lunch
type: Class
subclass of: Lunch
subclass of: Restriction
  on property: SIO_000061
  some values from: school
type: NamedIndividual
type: NodeShape
comment: Lunch meal prepared by, and served at school.

Reheating Food or Beverage in a Plastic Container
type: Class
subclass of: food reheating
subclass of: Restriction
  on property: SIO_000230
  some values from: Class
    intersection of: food product
    intersection of: Restriction
      on property: SIO_000128
      some values from: plastic container
type: NamedIndividual
type: NodeShape
comment: Reheating food (including beverages) in a plastic container; the food may have been placed in the plastic container for the purposes of reheating, or it may have been packaged in plastic as a single product unit.

Eats School Breakfast
type: Class
subclass of: Diet and Nutrition
subclass of: Eating or Drinking
subclass of: Restriction
  on property: SIO_000230
  some values from: School Breakfast
type: NamedIndividual
type: NodeShape
comment: The act of eating a school prepared breakfast.

Child Stress Assessment
type: Class
subclass of: Assessment
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000139
  some values from: Child
subclass of: Restriction
  on property: SIO_000215
  some values from: CAO_00518
type: NamedIndividual
type: NodeShape
comment: A qualitative assessment of the level of stress experienced by a child.

Never Feels Stressed
type: Class
subclass of: Child Stress Assessment
subclass of: SIO_001289
type: NamedIndividual
type: NodeShape
comment: This class denotes Never Feels Stressed

Rarely Feels Stressed
type: Class
subclass of: Child Stress Assessment
subclass of: SIO_001290
type: NamedIndividual
type: NodeShape
comment: This class denotes Rarely Feels Stressed

Sometimes Feels Stressed
type: Class
subclass of: Child Stress Assessment
subclass of: SIO_001290
type: NamedIndividual
type: NodeShape
comment: This class denotes Sometimes Feels Stressed

Often Feels Stressed
type: Class
subclass of: Child Stress Assessment
subclass of: SIO_001291
type: NamedIndividual
type: NodeShape
comment: This class denotes Often Feels Stressed

Always Feels Stressed
type: Class
subclass of: Child Stress Assessment
subclass of: SIO_001292
type: NamedIndividual
type: NodeShape
comment: This class denotes Always Feels Stressed

Smokes 1-4 Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 1
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 4
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of smoking between 1 and 4 cigarettes per day
notation: HHEAR_579

Smokes 5-14 Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 5
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 14
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of smoking between 5 and 14 cigarettes per day
notation: HHEAR_577

Smokes 15-24 Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 15
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 24
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of smoking between 15 and 24 cigarettes per day
notation: HHEAR_578

Smokes 25-35 Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 25
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 35
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of smoking between 25 and 35 cigarettes per day
notation: HHEAR_592

Smokes 36-44 Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 36
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 44
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: NodeShape
comment: The act of smoking between 36 and 44 cigarettes per day

Smokes 45+ Cigarettes Per Day
type: Class
subclass of: EFO_0006525
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 45
subclass of: Restriction
  on property: SIO_000221
  has value: HHEAR_00611
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The act of smoking 45 or more cigarettes per day
notation: HHEAR_595

Has Breastfed At Least Once
type: Class
subclass of: Breast Feeding
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Child has breastfed at least once
notation: HHEAR_566

Has Never Breastfed
type: Class
equivalent class: Class
  intersection of: Feeding Method
  intersection of: Class
    complement of: Has Breastfed At Least Once
subclass of: Does Not Breastfeed
subclass of: Class
  complement of: Has Breastfed At Least Once
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes has never breastfed
notation: HHEAR_567

Number of Members in Household
type: Class
subclass of: Demographic
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Household
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The number of people living in a household

Some College Up To And Including Bachelors Degree
type: Class
subclass of: Some College
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some College Up To And Including Bachelors Degree
notation: HHEAR_593

Twenty Four Hours Prior to Baseline
type: Class
subclass of: duration
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
comment: This class denotes Twenty Four Hours Prior to Baseline

Invasive Mechanical Ventilator Assisted Respiration
type: Class
subclass of: artificial respiration
subclass of: respiration
subclass of: Restriction
  on property: SIO_000139
  some values from: EFO_0010720
type: NamedIndividual
type: NodeShape
comment: Respiration that requires assistance from an invasive mechanical respirator.

ICU Admission Not Requiring Tracheostomy
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000250
      some values from: tracheostomy
subclass of: ICU Admission By Tracheostomy Status
subclass of: Class
  complement of: Restriction
    on property: SIO_000250
    some values from: tracheostomy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An ICU Admission of a patient that does not require a tracheostomy immediately upon admission.
notation: HHEAR_429

ICU Admission By Tracheostomy Status
type: Class
subclass of: Medical History
subclass of: ICU Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of ICU Admission; it is used to differentiate between when patients require a tracheostomy upon ICU admission versus when they do not.

ICU Admission By Blood Transfusion Status
type: Class
subclass of: ICU Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of ICU Admission; it is used to differentiate between when patients require a blood transfusion during their ICU admission versus when they do not.

ICU Admission Requiring Blood Transfusion
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Restriction
    on property: SIO_000250
    some values from: blood transfusion
subclass of: ICU Admission By Blood Transfusion Status
subclass of: Restriction
  on property: SIO_000250
  some values from: blood transfusion
disjoint with: ICU Admission Not Requiring Blood Transfusion
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An ICU Admission of a patient that requires a blood transfusion upon admission.
notation: HHEAR_430

ICU Admission Not Requiring Blood Transfusion
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000250
      some values from: blood transfusion
subclass of: ICU Admission By Blood Transfusion Status
subclass of: Class
  complement of: Restriction
    on property: SIO_000250
    some values from: blood transfusion
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An ICU Admission of a patient that does not require a blood transfusion upon admission.
notation: HHEAR_431

Hospital Admission By Admission Type
type: Class
subclass of: Hospital Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of Hospital Admission; this class is used to differentiate the reasons for the hospital admission, Medical, Surgical, or Trauma.

ICU Admission By Re-admission Status
type: Class
subclass of: ICU Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of ICU Admission; this class is used to distinguish between admissions of patients for the first time versus when a patient is readmitted to the ICU after previously being discharged.

ICU First Admission
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000249
      some values from: ICU Discharge
subclass of: ICU Admission By Re-admission Status
subclass of: Class
  complement of: Restriction
    on property: SIO_000249
    some values from: ICU Discharge
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes the first time a patient is admitted to an ICU.
notation: HHEAR_432

ICU Admission By Mechanical Ventilation Status
type: Class
subclass of: Medical History
subclass of: ICU Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of ICU Admission; it is used to differentiate between when patients require a invasive mechanical ventilation (dialysis, nitric oxide ventilation, or ECMO) during their ICU admission versus when they do not.

ICU Admission Requiring Mechanical Ventilation
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Restriction
    on property: SIO_000250
    some values from: EFO_0010720
subclass of: ICU Admission By Mechanical Ventilation Status
subclass of: Restriction
  on property: SIO_000250
  some values from: EFO_0010720
disjoint with: ICU Admission Not Requiring Mechanical Ventilation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes ICU Admission Requiring Mechanical Ventilation
notation: HHEAR_437

ICU Admission Not Requiring Mechanical Ventilation
type: Class
equivalent class: Class
  intersection of: ICU Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000250
      some values from: EFO_0010720
subclass of: ICU Admission By Mechanical Ventilation Status
subclass of: Class
  complement of: Restriction
    on property: SIO_000250
    some values from: EFO_0010720
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes ICU Admission Not Requiring Mechanical Ventilation
notation: HHEAR_438

Hospital Admission By Prior Home Medical Technology Use
type: Class
subclass of: Hospital Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of Hospital Admission; differentiates hospital admissions by whether or not the patient required home medical technology use prior to admission.

Required Home Medical Technology Prior to Hospital Admission
type: Class
equivalent class: Class
  intersection of: Hospital Admission
  intersection of: Restriction
    on property: SIO_000249
    some values from: Home Medical Technology
subclass of: Hospital Admission By Prior Home Medical Technology Use
subclass of: Restriction
  on property: SIO_000249
  some values from: Home Medical Technology
disjoint with: Did Not Require Home Medical Technology Prior to Hospital Admission
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes hospital admissions in which the patient required the use of home medical technology prior to admission.
notation: HHEAR_433

Did Not Require Home Medical Technology Prior to Hospital Admission
type: Class
equivalent class: Class
  intersection of: Hospital Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000249
      some values from: Home Medical Technology
subclass of: Hospital Admission By Prior Home Medical Technology Use
subclass of: Class
  complement of: Restriction
    on property: SIO_000249
    some values from: Home Medical Technology
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes hospital admissions in which the patient did not require the use of home medical technology prior to admission.
notation: HHEAR_434

Hospital Admission By Admission Source
type: Class
subclass of: Hospital Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of Hospital Admission; this class is used to differentiate between admissions that originate from the ER department of the study hospital versus those that do not.

Hospital Admission Not From Study Emergency Department
type: Class
subclass of: Hospital Admission By Admission Source
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An admission into a hospital where a clinical study is being conducted, and the subject was not previously in the study hospital's emergency department.
notation: HHEAR_436

Pediatric ICU Admission
type: Class
subclass of: ICU Admission
subclass of: Restriction
  on property: SIO_000061
  some values from: Pediatric Intensive Care Unit
type: NamedIndividual
type: NodeShape
comment: The admission into a pediatric ICU unit.

Duration of Healthcare Facility Admission
type: Class
subclass of: duration
subclass of: Healthcare Access
subclass of: SIO_000070
subclass of: Restriction
  on property: SIO_000215
  some values from: Healthcare Facility Admission
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The duration of time a patient is admitted into a healthcare facility

Duration of Hospital Admission
type: Class
subclass of: Duration of Healthcare Facility Admission
subclass of: Restriction
  on property: SIO_000215
  some values from: Hospital Admission
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is admitted into a hospital

Duration of Pediatric ICU Admission
type: Class
subclass of: Duration of Healthcare Facility Admission
subclass of: Restriction
  on property: SIO_000215
  some values from: Pediatric ICU Admission
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is admitted into a pediatric intensive care unit

Duration of Medical Procedure
type: Class
subclass of: duration
subclass of: Medical History
subclass of: Restriction
  on property: SIO_000215
  some values from: SIO_001024
type: NamedIndividual
type: NodeShape
comment: The length of time a patient undergoes a medical procedure

Duration of Vasopressor Agent Therapy
type: Class
subclass of: Duration of Medical Procedure
subclass of: Restriction
  on property: SIO_000215
  some values from: vasopressor agent therapy
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient undergoes vasopressor agent therapy

Duration of Central Venous Cannula Insertion
type: Class
subclass of: Duration of Medical Procedure
subclass of: Restriction
  on property: SIO_000215
  some values from: central venous cannula insertion
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient undergoes a central venous cannula insertion procedure

Duration of Noninvasive Positive-Pressure Ventilation
type: Class
subclass of: Duration of Medical Procedure
subclass of: Restriction
  on property: SIO_000215
  some values from: noninvasive positve-pressure ventilation
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient undergoes noninvasive positive-pressure ventilation

ICU Discharge By Oxygen Use
type: Class
subclass of: ICU Discharge
type: NamedIndividual
type: NodeShape
comment: A subclass of ICU Discharge; this class differentiates between whether or not a patient is discharged from the ICU on oxygen.

ICU Discharge Not On Oxygen
type: Class
equivalent class: Class
  intersection of: ICU Discharge
  intersection of: Class
    complement of: Restriction
      on property: SIO_000250
      some values from: Oxygen Treatment
subclass of: ICU Discharge By Oxygen Use
subclass of: Class
  complement of: Restriction
    on property: SIO_000250
    some values from: Oxygen Treatment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An event in which a patient is discharged from an intensive care unit and is not given oxygen treatment.
notation: HHEAR_439

Hospital Discharge By Oxygen Use
type: Class
subclass of: Hospital Discharge
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of ICU Discharge; this class differentiates between whether or not a patient is discharged from a hospital on oxygen.

Hospital Discharge Not On Oxygen
type: Class
equivalent class: Class
  intersection of: Hospital Discharge
  intersection of: Class
    complement of: Restriction
      on property: SIO_000250
      some values from: Oxygen Treatment
subclass of: Hospital Discharge By Oxygen Use
subclass of: Class
  complement of: Restriction
    on property: SIO_000250
    some values from: Oxygen Treatment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An event in which a patient is discharged from a hospital and is not given oxygen treatment.
notation: HHEAR_440

Duration of Medical Intervention
type: Class
subclass of: duration
subclass of: Restriction
  on property: SIO_000215
  some values from: SIO_001398
type: NamedIndividual
type: NodeShape
comment: The length of time a patient receives some form of medical intervention

Duration of Oxygen Treatment
type: Class
subclass of: Medical History
subclass of: Duration of Medical Intervention
subclass of: Restriction
  on property: SIO_000215
  some values from: Oxygen Treatment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is receiving oxygen treatment as a medical intervention

Duration of Muscle Relaxant Use
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Duration of Medical Intervention
subclass of: Restriction
  on property: SIO_000215
  some values from: Uses Muscle Relaxants
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is taking muscle relaxants as a medical intervention

Duration of Antibiotic Use
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Duration of Medical Intervention
subclass of: Restriction
  on property: SIO_000215
  some values from: Uses Antibiotics
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient receives antibiotic treatment as a medical intervention

Duration of Invasive Mechanical Ventilation
type: Class
subclass of: Medical History
subclass of: Duration of Medical Intervention
subclass of: Restriction
  on property: SIO_000215
  some values from: EFO_0010720
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Duration of Invasive Mechanical Ventilation

Duration of Ventilator Free Respiration
type: Class
subclass of: duration
subclass of: Medical History
subclass of: Restriction
  on property: SIO_000215
  some values from: Ventilator Free Respiration
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is able to breathe without aid of mechanical ventilation.

Duration of Steroid Treatment
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Duration of Medical Intervention
subclass of: Restriction
  on property: SIO_000215
  some values from: Uses Steroid Treatment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient is receiving steroids as a medical treatment

Duration of Chest Tube Placement
type: Class
subclass of: Duration of Medical Procedure
subclass of: Restriction
  on property: SIO_000215
  some values from: Chest Tube Placement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a patient has a chest tube placed in their chest cavity as a medical procedure

Uses Antibiotics During Hospital Admission
type: Class
equivalent class: Class
  intersection of: Hospital Admission
  intersection of: Restriction
    on property: SIO_000325
    some values from: Uses Antibiotics
subclass of: Hospital Admission By Antibiotic Use
subclass of: Restriction
  on property: SIO_000325
  some values from: Uses Antibiotics
disjoint with: Does Not Use Antibiotics During Hospital Admission
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class indicates when a patient is using antibiotics during a hospital admission. The use of the antibiotics may precede the hospital admission, extend beyond hospital discharge, or occur wholly within the hospital admission.
notation: HHEAR_441

Hospital Admission By Antibiotic Use
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: Hospital Admission
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A subclass of Hospital Admission; this class differentiates between when a patient uses antibiotics at any time during a hospital admission versus when they do not.

Does Not Use Antibiotics During Hospital Admission
type: Class
equivalent class: Class
  intersection of: Hospital Admission
  intersection of: Class
    complement of: Restriction
      on property: SIO_000325
      some values from: Uses Antibiotics
subclass of: Hospital Admission By Antibiotic Use
subclass of: Class
  complement of: Restriction
    on property: SIO_000325
    some values from: Uses Antibiotics
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class indicates when a patient does not antibiotics during a hospital admission. The patient may have used antibiotics prior to hospital admission or after discharge.
notation: HHEAR_442

Employment not in Medical Field
type: Class
subclass of: Employment
disjoint with: Employment in Medical Field
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The status of being employed but not in a medical field
notation: HHEAR_448

Annual Income $24,999 or Less
type: Class
subclass of: Annual Income $39,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 24999
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $24,999 or Less
notation: HHEAR_444

Annual Income $25,000 to $49,999
type: Class
subclass of: Annual Income $25,000 to $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 49999
subclass of: Restriction
  on property: minValue
  has value: 25000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $25,000 to $49,999
notation: HHEAR_445

Annual Income $100,000 to $124,999
type: Class
subclass of: Annual Income $100,000 to $149,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 124999
subclass of: Restriction
  on property: minValue
  has value: 100000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $100,000 to $124,999
notation: HHEAR_446

Annual Income More Than $125,000
type: Class
subclass of: Annual Income More Than $120,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 125000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income More Than $125,000
notation: HHEAR_447

Employment in Medical Field
type: Class
equivalent class: Class
  intersection of: Employment
  intersection of: SIO_000712
subclass of: Employment
subclass of: SIO_000712
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Employment in some medical field
notation: HHEAR_449

High School or Some College
type: Class
equivalent class: Class
  union of: Some College
  union of: Graduated From High School
subclass of: Education
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: High school or some college educational status
notation: HHEAR_450

PROMIS Pediatric Instrument Bank
type: Class
subclass of: Questionnaire
subclass of: Restriction
  on property: SIO_000059
  some values from: PROMIS Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes PROMIS Pediatric Instrument Bank

PROMIS Pediatric Psychological Stress Experiences
type: Class
subclass of: PROMIS Pediatric Instrument Bank
type: NamedIndividual
type: NodeShape
comment: This class denotes PROMIS Pediatric Psychological Stress Experiences

Questionnaire Response
type: Class
subclass of: SIO_000785
type: NamedIndividual
type: NodeShape
comment: A response to a question in a questionnaire

PROMIS Questionnaire Response
type: Class
subclass of: Physical And Mental Assessment
subclass of: Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: A response to a question in the PROMIS questionnaire See also <http://purl.bioontology.org/ontology/LNC/LP102768-1>

PROMIS Psychological Stress Experiences Response
type: Class
subclass of: PROMIS Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: A response to a PROMIS Pediatric Psychological Stress Experiences question

I Felt Stressed Response
type: Class
subclass of: PROMIS Psychological Stress Experiences Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the question "I felt stressed" in the PROMIS Questionnaire

I Always Felt Stressed Response
type: Class
subclass of: Always Feels Stressed
subclass of: I Felt Stressed Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Always Felt Stressed Response
notation: HHEAR_690

I Often Felt Stressed Response
type: Class
subclass of: Often Feels Stressed
subclass of: I Felt Stressed Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Often Felt Stressed Response
notation: HHEAR_454

I Sometimes Felt Stressed Response
type: Class
subclass of: Sometimes Feels Stressed
subclass of: I Felt Stressed Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Sometimes Felt Stressed Response
notation: HHEAR_456

I Rarely Felt Stressed Response
type: Class
subclass of: Rarely Feels Stressed
subclass of: I Felt Stressed Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Rarely Felt Stressed Response
notation: HHEAR_455

I Never Felt Stressed Response
type: Class
subclass of: Never Feels Stressed
subclass of: I Felt Stressed Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Never Felt Stressed Response
notation: HHEAR_453

I Felt Problems Kept Piling Up Response
type: Class
subclass of: PROMIS Psychological Stress Experiences Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the PROMIS questionnaire question "I felt that my problems kept piling up."

I Never Felt Problems Kept Piling Up Response
type: Class
subclass of: I Felt Problems Kept Piling Up Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Never Felt Problems Kept Piling Up Response
notation: HHEAR_458

I Rarely Felt Problems Kept Piling Up Response
type: Class
subclass of: I Felt Problems Kept Piling Up Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Rarely Felt Problems Kept Piling Up Response
notation: HHEAR_460

I Sometimes Felt Problems Kept Piling Up Response
type: Class
subclass of: I Felt Problems Kept Piling Up Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Sometimes Felt Problems Kept Piling Up Response
notation: HHEAR_461

I Often Felt Problems Kept Piling Up Response
type: Class
subclass of: I Felt Problems Kept Piling Up Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Often Felt Problems Kept Piling Up Response
notation: HHEAR_459

I Always Felt Problems Kept Piling Up Response
type: Class
subclass of: I Felt Problems Kept Piling Up Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Always Felt Problems Kept Piling Up Response
notation: HHEAR_457

I Felt Overwhelmed Response
type: Class
subclass of: PROMIS Psychological Stress Experiences Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the PROMIS questionnaire question "I felt overwhelmed."

I Never Felt Overwhelmed Response
type: Class
subclass of: I Felt Overwhelmed Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Never Felt Overwhelmed Response
notation: HHEAR_463

I Rarely Felt Overwhelmed Response
type: Class
subclass of: I Felt Overwhelmed Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Rarely Felt Overwhelmed Response
notation: HHEAR_465

I Sometimes Felt Overwhelmed Response
type: Class
subclass of: I Felt Overwhelmed Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Sometimes Felt Overwhelmed Response
notation: HHEAR_466

I Often Felt Overwhelmed Response
type: Class
subclass of: I Felt Overwhelmed Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Often Felt Overwhelmed Response
notation: HHEAR_464

I Always Felt Overwhelmed Response
type: Class
subclass of: I Felt Overwhelmed Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Always Felt Overwhelmed Response
notation: HHEAR_462

I Felt Unable To Manage Things In My Life Response
type: Class
subclass of: PROMIS Psychological Stress Experiences Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the PROMIS questionnaire question "I felt unable to manage things in my life."

I Never Felt Unable To Manage Things In My Life Response
type: Class
subclass of: I Felt Unable To Manage Things In My Life Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Never Felt Unable To Manage Things In My Life Response
notation: HHEAR_468

I Rarely Felt Unable To Manage Things In My Life Response
type: Class
subclass of: I Felt Unable To Manage Things In My Life Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Rarely Felt Unable To Manage Things In My Life Response
notation: HHEAR_470

I Sometimes Felt Unable To Manage Things In My Life Response
type: Class
subclass of: I Felt Unable To Manage Things In My Life Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Sometimes Felt Unable To Manage Things In My Life Response
notation: HHEAR_471

I Often Felt Unable To Manage Things In My Life Response
type: Class
subclass of: I Felt Unable To Manage Things In My Life Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Often Felt Unable To Manage Things In My Life Response
notation: HHEAR_469

I Always Felt Unable To Manage Things In My Life Response
type: Class
subclass of: I Felt Unable To Manage Things In My Life Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes I Always Felt Unable To Manage Things In My Life Response
notation: HHEAR_467

Preschool-age Children's Physical Activity Questionnaire Response
type: Class
subclass of: built environment
subclass of: Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: A response to a questionnaire on perceptions of neighborhood safety for child outdoor activity

Neighborhood Is Safe Response
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the question "Is my child's neighborhood safe?"

Strongly Agree Neighborhood Is Safe Response
type: Class
subclass of: Strongly Agree
subclass of: Neighborhood Is Safe Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Neighborhood Is Safe Response
notation: HHEAR_474

Agree Neighborhood Is Safe Response
type: Class
subclass of: Agree
subclass of: Neighborhood Is Safe Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Neighborhood Is Safe Response
notation: HHEAR_472

Disagree Neighborhood Is Safe Response
type: Class
subclass of: Disagree
subclass of: Neighborhood Is Safe Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Neighborhood Is Safe Response
notation: HHEAR_473

Strongly Disagree Neighborhood Is Safe Response
type: Class
subclass of: Strongly Disagree
subclass of: Neighborhood Is Safe Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Neighborhood Is Safe Response
notation: HHEAR_475

Local Streets Have Usable Footpaths Response
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "There are useable footpaths on most of the streets in my local area."

Strongly Agree Local Streets Have Usable Footpaths Response
type: Class
subclass of: Strongly Agree
subclass of: Local Streets Have Usable Footpaths Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Local Streets Have Usable Footpaths Response
notation: HHEAR_478

Agree Local Streets Have Usable Footpaths Response
type: Class
subclass of: Agree
subclass of: Local Streets Have Usable Footpaths Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Local Streets Have Usable Footpaths Response
notation: HHEAR_476

Disagree Local Streets Have Usable Footpaths Response
type: Class
subclass of: Disagree
subclass of: Local Streets Have Usable Footpaths Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Local Streets Have Usable Footpaths Response
notation: HHEAR_477

Strongly Disagree Local Streets Have Usable Footpaths Response
type: Class
subclass of: Strongly Disagree
subclass of: Local Streets Have Usable Footpaths Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Local Streets Have Usable Footpaths Response
notation: HHEAR_479

Major Barriers Or Dangers To Walking Response
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "There are major barriers or dangers to walking with my child in my neighborhood that make it hard to get from place to place (e.g., major roads, railway lines, storm water drains or rivers)."

Strongly Agree Major Barriers Or Dangers To Walking Response
type: Class
subclass of: Strongly Agree
subclass of: Major Barriers Or Dangers To Walking Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Major Barriers Or Dangers To Walking Response
notation: HHEAR_482

Agree Major Barriers Or Dangers To Walking Response
type: Class
subclass of: Agree
subclass of: Major Barriers Or Dangers To Walking Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Major Barriers Or Dangers To Walking Response
notation: HHEAR_480

Disagree Major Barriers Or Dangers To Walking Response
type: Class
subclass of: Disagree
subclass of: Major Barriers Or Dangers To Walking Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Major Barriers Or Dangers To Walking Response
notation: HHEAR_481

Strongly Disagree Major Barriers Or Dangers To Walking Response
type: Class
subclass of: Strongly Disagree
subclass of: Major Barriers Or Dangers To Walking Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Major Barriers Or Dangers To Walking Response
notation: HHEAR_483

Street Traffic Makes It Dangerous To Walk Response
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "There is so much traffic along the streets that it makes it difficult or dangerous to walk with my child in my neighborhood."

Strongly Agree Street Traffic Makes It Dangerous To Walk Response
type: Class
subclass of: Strongly Agree
subclass of: Street Traffic Makes It Dangerous To Walk Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Street Traffic Makes It Dangerous To Walk Response
notation: HHEAR_486

Agree Street Traffic Makes It Dangerous To Walk Response
type: Class
subclass of: Agree
subclass of: Street Traffic Makes It Dangerous To Walk Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Street Traffic Makes It Dangerous To Walk Response
notation: HHEAR_484

Disagree Street Traffic Makes It Dangerous To Walk Response
type: Class
subclass of: Disagree
subclass of: Street Traffic Makes It Dangerous To Walk Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Street Traffic Makes It Dangerous To Walk Response
notation: HHEAR_485

Strongly Disagree Street Traffic Makes It Dangerous To Walk Response
type: Class
subclass of: Strongly Disagree
subclass of: Street Traffic Makes It Dangerous To Walk Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Street Traffic Makes It Dangerous To Walk Response
notation: HHEAR_487

Safe To Walk With Child In Neighborhood Response
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "There are sufficient traffic lights or pedestrian crossings to make it safe to walk with my child around my neighborhood."

Strongly Agree Safe To Walk With Child In Neighborhood Response
type: Class
subclass of: Strongly Agree
subclass of: Safe To Walk With Child In Neighborhood Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Safe To Walk With Child In Neighborhood Response
notation: HHEAR_490

Agree Safe To Walk With Child In Neighborhood Response
type: Class
subclass of: Agree
subclass of: Safe To Walk With Child In Neighborhood Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Safe To Walk With Child In Neighborhood Response
notation: HHEAR_488

Disagree Safe To Walk With Child In Neighborhood Response
type: Class
subclass of: Disagree
subclass of: Safe To Walk With Child In Neighborhood Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Safe To Walk With Child In Neighborhood Response
notation: HHEAR_489

Strongly Disagree Safe To Walk With Child In Neighborhood Response
type: Class
subclass of: Strongly Disagree
subclass of: Safe To Walk With Child In Neighborhood Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Safe To Walk With Child In Neighborhood Response
notation: HHEAR_491

Crime Makes It Unsafe To Walk In Daytime
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "The level of crime in my neighborhood makes it unsafe to go on walks with my child during the day."

Strongly Agree Crime Makes It Unsafe To Walk In Daytime
type: Class
subclass of: Strongly Agree
subclass of: Crime Makes It Unsafe To Walk In Daytime
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Crime Makes It Unsafe To Walk In Daytime
notation: HHEAR_494

Agree Crime Makes It Unsafe To Walk In Daytime
type: Class
subclass of: Agree
subclass of: Crime Makes It Unsafe To Walk In Daytime
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Crime Makes It Unsafe To Walk In Daytime
notation: HHEAR_492

Disagree Crime Makes It Unsafe To Walk In Daytime
type: Class
subclass of: Disagree
subclass of: Crime Makes It Unsafe To Walk In Daytime
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Crime Makes It Unsafe To Walk In Daytime
notation: HHEAR_493

Strongly Disagree Crime Makes It Unsafe To Walk In Daytime
type: Class
subclass of: Strongly Disagree
subclass of: Crime Makes It Unsafe To Walk In Daytime
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Crime Makes It Unsafe To Walk In Daytime
notation: HHEAR_495

Local Shops Are Walkable From Home
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "The local shop(s) are within easy walking distance of my home."

Strongly Agree Local Shops Are Walkable From Home
type: Class
subclass of: Strongly Agree
subclass of: Local Shops Are Walkable From Home
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Local Shops Are Walkable From Home
notation: HHEAR_498

Agree Local Shops Are Walkable From Home
type: Class
subclass of: Agree
subclass of: Local Shops Are Walkable From Home
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Local Shops Are Walkable From Home
notation: HHEAR_496

Disagree Local Shops Are Walkable From Home
type: Class
subclass of: Disagree
subclass of: Local Shops Are Walkable From Home
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Local Shops Are Walkable From Home
notation: HHEAR_497

Strongly Disagree Local Shops Are Walkable From Home
type: Class
subclass of: Strongly Disagree
subclass of: Local Shops Are Walkable From Home
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Local Shops Are Walkable From Home
notation: HHEAR_499

Local Parks Are Too Dangerous For My Child
type: Class
subclass of: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A response to the questionnaire statement "There are dangers (e.g., dogs or undesirable people) in the local park(s) so I avoid taking my child there."

Strongly Agree Local Parks Are Too Dangerous For My Child
type: Class
subclass of: Strongly Agree
subclass of: Local Parks Are Too Dangerous For My Child
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Agree Local Parks Are Too Dangerous For My Child
notation: HHEAR_502

Agree Local Parks Are Too Dangerous For My Child
type: Class
subclass of: Agree
subclass of: Local Parks Are Too Dangerous For My Child
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Agree Local Parks Are Too Dangerous For My Child
notation: HHEAR_500

Disagree Local Parks Are Too Dangerous For My Child
type: Class
subclass of: Disagree
subclass of: Local Parks Are Too Dangerous For My Child
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Disagree Local Parks Are Too Dangerous For My Child
notation: HHEAR_501

Strongly Disagree Local Parks Are Too Dangerous For My Child
type: Class
subclass of: Strongly Disagree
subclass of: Local Parks Are Too Dangerous For My Child
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Strongly Disagree Local Parks Are Too Dangerous For My Child
notation: HHEAR_503

Residential Yard
type: Class
subclass of: domestic garden
type: NamedIndividual
type: NodeShape
comment: A subclass of domestic garden; a residential yard is an area attached or adjacent to a single family or multi-family house where domestic leisure activities typically occur.

Private Residential Yard
type: Class
subclass of: Residential Yard
type: NamedIndividual
type: NodeShape
comment: A back yard for a residential house that is not shared among multiple houses

Small Residential Yard
type: Class
subclass of: Residential Yard
type: NamedIndividual
type: NodeShape
comment: This class denotes Small Residential Yard

Medium Residential Yard
type: Class
subclass of: Residential Yard
type: NamedIndividual
type: NodeShape
comment: This class denotes Medium Residential Yard

Large Residential Yard
type: Class
subclass of: Residential Yard
type: NamedIndividual
type: NodeShape
comment: This class denotes Large Residential Yard

Residential Building With A Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000028
    some values from: Residential Yard
subclass of: Residential Building
subclass of: Restriction
  on property: SIO_000028
  some values from: Residential Yard
disjoint with: Residential Building Without A Yard
type: NamedIndividual
type: NodeShape
comment: A residential building that has an attached yard or garden where domestic leisure activities occur.

Residential Building Without A Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Class
    complement of: Restriction
      on property: SIO_000028
      some values from: Residential Yard
subclass of: Residential Building Without A Private Yard
subclass of: Class
  complement of: Restriction
    on property: SIO_000028
    some values from: Residential Yard
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A residential building that does not have a yard attached or adjacent to it
notation: HHEAR_588

Residential Building Without A Private Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Class
    complement of: Restriction
      on property: SIO_000028
      some values from: Private Residential Yard
subclass of: Residential Building
subclass of: Class
  complement of: Restriction
    on property: SIO_000028
    some values from: Private Residential Yard
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A residential building that has an attached or adjacent yard that is not private
notation: HHEAR_589

Residential Building With A Small Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000028
    some values from: Small Residential Yard
subclass of: Residential Building With A Yard
subclass of: Restriction
  on property: SIO_000028
  some values from: Small Residential Yard
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A residential building with a small yard attached or adjacent to it
notation: HHEAR_585

Residential Building With A Medium Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000028
    some values from: Medium Residential Yard
subclass of: Residential Building With A Yard
subclass of: Restriction
  on property: SIO_000028
  some values from: Medium Residential Yard
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A residential building with a medium yard attached or adjacent to it
notation: HHEAR_586

Residential Building With A Large Yard
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000028
    some values from: Large Residential Yard
subclass of: Residential Building With A Yard
subclass of: Restriction
  on property: SIO_000028
  some values from: Large Residential Yard
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A residential building with a medium yard attached or adjacent to it
notation: HHEAR_582

Preschool-age Children's Physical Activity Questionnaire
type: Class
subclass of: Questionnaire
subclass of: Restriction
  on property: SIO_000059
  some values from: Preschool-age Children's Physical Activity Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: The Preschool-age Children's Physical Activity Questionnaire (Pre-PAQ) was designed to measure activity of preschool-age children in the home environment in population studies. Reference: The validity and reliability of a home environment preschool-age physical activity questionnaire (Pre-PAQ) Genevieve M Dwyer, Louise L Hardy, Jennifer K Peat & Louise A Baur International Journal of Behavioral Nutrition and Physical Activity volume 8, Article number: 86 (2011) https://ijbnpa.biomedcentral.com/articles/10.1186/1479-5868-8-86

Tanner Scale For Breast Development
type: Class
subclass of: Tanner Scale
type: NamedIndividual
type: NodeShape
comment: This class denotes Tanner Scale For Breast Development

Tanner Scale For Genital Development
type: Class
subclass of: Tanner Scale
type: NamedIndividual
type: NodeShape
comment: This class denotes Tanner Scale For Genital Development

Tanner Scale For Pubic Hair Development
type: Class
subclass of: Tanner Scale
type: NamedIndividual
type: NodeShape
comment: This class denotes Tanner Scale For Pubic Hair Development

Tanner Breast Development Stage I
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: no glandular tissue: areola follows the skin contours of the chest (prepubertal) (typically age 10 and younger) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_573

Tanner Scale For Breast Development (Assigned By Child's Mother)
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Breast Development as assigned by the child's mother

Tanner Scale For Genital Development (Assigned By Child's Mother)
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Genital Development as assigned by the child's mother

Tanner Scale For Male Pubic Hair Development (Assigned By Child's Mother)
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Male Pubic Hair Development as assigned by the child's mother

Tanner Breast Development Stage II
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: breast bud forms, with small area of surrounding glandular tissue; areola begins to widen (10–11.5) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_570

Tanner Breast Development Stage III
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: breast begins to become more elevated, and extends beyond the borders of the areola, which continues to widen but remains in contour with surrounding breast (11.5–13) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_571

Tanner Breast Development Stage IV
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: increased breast sizing and elevation; areola and papilla form a secondary mound projecting from the contour of the surrounding breast (13–15) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_568

Tanner Breast Development Stage V
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: breast reaches final adult size; areola returns to contour of the surrounding breast, with a projecting central papilla. (15+) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_569

Tanner Genital Development Stage I
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: testicular volume less than 1.5 ml; small penis (prepubertal; typically age 9 and younger) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_580

Tanner Genital Development Stage II
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: testicular volume between 1.6 and 6 ml; skin on scrotum thins, reddens and enlarges; penis length unchanged (9–11) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_581

Tanner Genital Development Stage III
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: testicular volume between 6 and 12 ml; scrotum enlarges further; penis begins to lengthen (11–12.5) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_591

Tanner Genital Development Stage IV
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: testicular volume between 12 and 20 ml; scrotum enlarges further and darkens; penis increases in length (12.5–14) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_684

Tanner Genital Development Stage V
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: testicular volume greater than 20 ml; adult scrotum and penis (14+) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_590

Tanner Scale For Male Pubic Hair Development
type: Class
subclass of: Tanner Scale For Pubic Hair Development
type: NamedIndividual
type: NodeShape
comment: This class denotes Tanner Scale For Male Pubic Hair Development

Tanner Scale For Female Pubic Hair Development
type: Class
subclass of: Tanner Scale For Pubic Hair Development
type: NamedIndividual
type: NodeShape
comment: This class denotes Tanner Scale For Female Pubic Hair Development

Tanner Scale For Female Pubic Hair Development (Assigned By Child's Mother)
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Female Pubic Hair Development as assigned by the child's mother

Tanner Female Pubic Hair Development Stage I
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: no pubic hair at all (prepubertal) (typically age 10 and younger) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_587

Tanner Female Pubic Hair Development Stage II
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: small amount of long, downy hair with slight pigmentation on the labia majora (10–11.5) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_583

Tanner Female Pubic Hair Development Stage III
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: hair becomes more coarse and curly, and begins to extend laterally (11.5–13) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_584

Tanner Female Pubic Hair Development Stage IV
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: adult-like hair quality, extending across pubis but sparing medial thighs (13–15) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_680

Tanner Female Pubic Hair Development Stage V
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: hair extends to medial surface of the thighs (15+) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_575

Tanner Male Pubic Hair Development Stage I
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: no pubic hair at all (prepubertal) (typically age 10 and younger) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_576

Tanner Male Pubic Hair Development Stage II
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: small amount of long, downy hair with slight pigmentation at the base of the penis and scrotum (10–11.5) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_574

Tanner Male Pubic Hair Development Stage III
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: hair becomes more coarse and curly, and begins to extend laterally (11.5–13) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_678

Tanner Male Pubic Hair Development Stage IV
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: adult-like hair quality, extending across pubis but sparing medial thighs (13–15) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_679

Tanner Male Pubic Hair Development Stage V
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: hair extends to medial surface of the thighs (15+) Source: Adolescent health care : a practical guide. Neinstein, Lawrence S., Neinstein, Lawrence S. (5th ed.). Philadelphia: Lippincott Williams & Wilkins. 2008. ISBN 9780781792561. OCLC 148727849.
notation: HHEAR_572

Four Factor Index of Social Status Questionnaire
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: Four Factor Index of Social Status by August B. Hollingshead Reference: https://sociology.yale.edu/sites/default/files/files/yjs_fall_2011.pdf

Four Factor Index of Social Status Questionnaire Response
type: Class
subclass of: Demographic
subclass of: Socioeconomic Status
subclass of: Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Four Factor Index of Social Status Questionnaire Response

Occupation Category 1
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 1=farm laborers, menial service workers, students, housewives, (dependent on welfare, no regular occupation),
notation: HHEAR_508

Occupation Category 2
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Occupation Category 2, i.e. 2=unskilled workers
notation: HHEAR_509

Occupation Category 3
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 3=machine operators and semi-skilled workers
notation: HHEAR_510

Occupation Category 4
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 4=smaller business owners (<$25,000), skilled manual laborers, craftsmen, tenant farmers
notation: HHEAR_511

Occupation Category 5
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 5=clerical and sales workers, small farm and business owners (business valued at $25,000-50,000)
notation: HHEAR_512

Occupation Category 6
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 6=technicians, semi-professionals, small business owners (business valued at $50,000-70,000)
notation: HHEAR_513

Occupation Category 7
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 7=smaller business owners, farm owners, managers, minor professionals
notation: HHEAR_514

Occupation Category 8
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 8=administrators, lesser professionals, proprietor of medium-sized business
notation: HHEAR_515

Occupation Category 9
type: Class
subclass of: Occupation
subclass of: Four Factor Index of Social Status Questionnaire Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: 9=higher executive, proprietor of large businesses, major professional
notation: HHEAR_516

Less Than Grade 7
type: Class
subclass of: Less Than Grade 8
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Completed less than Grade 7
notation: HHEAR_507

Education Grade 8
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Finished Grade 8
notation: HHEAR_505

Education Grade 9
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Finished Grade 9
notation: HHEAR_506

Completed Graduate School
type: Class
subclass of: Some Postgraduate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes completed graduate school
notation: HHEAR_504

Other Caregiver
type: Class
subclass of: Caregiver
type: NamedIndividual
type: NodeShape
comment: An alternate or additional caregiver for a dependent person

Annual Income $10,000 to $14,999
type: Class
subclass of: Annual Income $5,001 to $15,000
subclass of: Annual Income $14,999 or Less
subclass of: Annual Income $10,000 to $19,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 14999
subclass of: Restriction
  on property: minValue
  has value: 10000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $10,000 to $14,999
notation: HHEAR_517

Annual Income $15,000 to $19,999
type: Class
subclass of: Annual Income $10,001 to $20,000
subclass of: Annual Income $15,000 to $24,999
subclass of: Annual Income $10,000 to $19,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 19999
subclass of: Restriction
  on property: minValue
  has value: 15000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $15,000 to $19,999
notation: HHEAR_518

Annual Income $20,000 to $24,999
type: Class
subclass of: Annual Income $15,000 to $24,999
subclass of: Annual Income $20,000 to $29,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 24999
subclass of: Restriction
  on property: minValue
  has value: 20000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $20,000 to $24,999
notation: HHEAR_519

Annual Income $45,000 to $64,999
type: Class
subclass of: Annual Income $40,001 to $70,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 64999
subclass of: Restriction
  on property: minValue
  has value: 45000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $45,000 to $64,999
notation: HHEAR_520

Annual Income More Than $65,000
type: Class
subclass of: Annual Income More Than $60,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 65000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income More Than $65,000
notation: HHEAR_521

Some Household Member Currently Smokes
type: Class
subclass of: Second Hand Smoke Exposure by Household Member
disjoint with: No Household Members Currently Smoke
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Someone living in the household currently smoke cigarettes, cigars or pipes.
notation: HHEAR_523

No Household Members Currently Smoke
type: Class
subclass of: Second Hand Smoke Exposure by Household Member
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: No one in the household living in your household currently smoke cigarettes, cigars or pipes.
notation: HHEAR_524

Spouse or Significant Other Living In Household Currently Smokes
type: Class
subclass of: Some Household Member Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The spouse or significant other living in a household currently smoke cigarettes, cigars or pipes
notation: HHEAR_525

Child Under 18 Living In Household Currently Smokes
type: Class
subclass of: Some Household Member Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A child under age 18 living in the household currently smoke cigarettes, cigars or pipes.
notation: HHEAR_526

Adult Child Living In Household Currently Smokes
type: Class
subclass of: Some Household Member Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An adult child living in the household currently smoke cigarettes, cigars or pipes
notation: HHEAR_527

Other Adults Living In Household Currently Smoke
type: Class
subclass of: Some Household Member Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Other adults in the home living in the household currently smoke cigarettes, cigars or pipes.
notation: HHEAR_528

Inconsistent Class
type: Class
subclass of: Nothing
type: NamedIndividual
type: Quality Value
comment: This class denotes Inconsistent Class
notation: HHEAR_522

Spouse or Significant Other and Child Under 18 Living In Household Currently Smoke
type: Class
equivalent class: Class
  intersection of: Spouse or Significant Other Living In Household Currently Smokes
  intersection of: Child Under 18 Living In Household Currently Smokes
subclass of: Spouse or Significant Other Living In Household Currently Smokes
subclass of: Child Under 18 Living In Household Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Spouse/SO and Child under age 18 living in the household currently smoke cigarettes, cigars or pipes.
notation: HHEAR_530

Has Been Exposed to Second Hand Smoke
type: Class
subclass of: Second Hand Smoke Exposure by Indicator Status
type: NamedIndividual
type: Quality Value
comment: This class denotes Has Been Exposed to Second Hand Smoke
notation: HHEAR_568

Has Not Been Exposed to Second Hand Smoke
type: Class
subclass of: Second Hand Smoke Exposure by Indicator Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Has Not Been Exposed to Second Hand Smoke
notation: HHEAR_531

Exposed to Second Hand Smoke at Home
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Home
notation: HHEAR_532

Exposed to Second Hand Smoke at Other Parent's House
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Other Parent's House
notation: HHEAR_533

Exposed to Second Hand Smoke in Primary Caregiver's Car
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Primary Caregiver's Car
notation: HHEAR_534

Exposed to Second Hand Smoke in Other Car
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Other Car
notation: HHEAR_535

Exposed to Second Hand Smoke in Outdoor Public Place
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Outdoor Public Place
notation: HHEAR_536

Exposed to Second Hand Smoke at Relative's House
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Relative's House
notation: HHEAR_537

Exposed to Second Hand Smoke at Friend's House
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Friend's House
notation: HHEAR_538

Exposed to Second Hand Smoke at Daycare
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Daycare
notation: HHEAR_539

Exposed to Second Hand Smoke at Home and in Primary Caregiver's Car
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Home
  intersection of: Exposed to Second Hand Smoke in Primary Caregiver's Car
subclass of: Exposed to Second Hand Smoke at Home
subclass of: Exposed to Second Hand Smoke in Primary Caregiver's Car
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Home and in Primary Caregiver's Car
notation: HHEAR_540

Exposed to Second Hand Smoke at Home and in Other Car
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Home
  intersection of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke at Home
subclass of: Exposed to Second Hand Smoke in Other Car
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Home and in Other Car
notation: HHEAR_541

Exposed to Second Hand Smoke at Home and in Outdoor Public Place
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Home
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Home
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Home and in Outdoor Public Place
notation: HHEAR_542

Exposed to Second Hand Smoke at Other Parent's House, in Other Car, and in Outdoor Public Place
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Other Parent's House
  intersection of: Exposed to Second Hand Smoke in Other Car
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Other Parent's House
subclass of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Other Parent's House, in Other Car, and in Outdoor Public Place
notation: HHEAR_543

Exposed to Second Hand Smoke at Other Parent's House and at Relative's House
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Other Parent's House
  intersection of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke at Other Parent's House
subclass of: Exposed to Second Hand Smoke at Relative's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Other Parent's House and at Relative's House
notation: HHEAR_544

Exposed to Second Hand Smoke in Primary Caregiver's Car, in Other Car, in Relative's House, and in Outdoor Public Space
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Primary Caregiver's Car
  intersection of: Exposed to Second Hand Smoke in Other Car
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
  intersection of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke in Primary Caregiver's Car
subclass of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Relative's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Primary Caregiver's Car, in Other Car, in Relative's House, and in Outdoor Public Space
notation: HHEAR_545

Exposed to Second Hand Smoke in Other Car and at Relative's House
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Other Car
  intersection of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke at Relative's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Other Car and at Relative's House
notation: HHEAR_546

Exposed to Second Hand Smoke in Other Car, at Relative's House, and at Friend's House
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Other Car
  intersection of: Exposed to Second Hand Smoke at Relative's House
  intersection of: Exposed to Second Hand Smoke at Friend's House
subclass of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke at Friend's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Other Car, at Relative's House, and at Friend's House
notation: HHEAR_547

Exposed to Second Hand Smoke in Outdoor Public Place and at Relative's House
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
  intersection of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Relative's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Outdoor Public Place and at Relative's House
notation: HHEAR_548

Exposed to Second Hand Smoke in Outdoor Public Place and at Friend's House
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
  intersection of: Exposed to Second Hand Smoke at Friend's House
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Friend's House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Outdoor Public Place and at Friend's House
notation: HHEAR_549

Exposed to Second Hand Smoke in Other Area
type: Class
subclass of: Second Hand Smoke Exposure by Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke in Other Area
notation: HHEAR_550

Exposed to Second Hand Smoke at Outdoor Public Place and Other Place
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
  intersection of: Exposed to Second Hand Smoke in Other Area
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke in Other Area
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Outdoor Public Place and Other Place
notation: HHEAR_551

Exposed to Second Hand Smoke at Other Parent's House, in Other Car, in Outdoor Public Place, at Relative's House, and in Other Area
type: Class
equivalent class: Class
  intersection of: Exposed to Second Hand Smoke at Other Parent's House
  intersection of: Exposed to Second Hand Smoke in Other Car
  intersection of: Exposed to Second Hand Smoke in Outdoor Public Place
  intersection of: Exposed to Second Hand Smoke at Relative's House
  intersection of: Exposed to Second Hand Smoke in Other Area
subclass of: Exposed to Second Hand Smoke at Other Parent's House
subclass of: Exposed to Second Hand Smoke in Other Car
subclass of: Exposed to Second Hand Smoke in Outdoor Public Place
subclass of: Exposed to Second Hand Smoke at Relative's House
subclass of: Exposed to Second Hand Smoke in Other Area
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Exposed to Second Hand Smoke at Other Parent's House, in Other Car, in Outdoor Public Place, at Relative's House, and in Other Area
notation: HHEAR_552

Unknown if Any Household Members Currently Smoke
type: Class
subclass of: Second Hand Smoke Exposure by Household Member
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Unknown if Any Household Members Currently Smoke
notation: HHEAR_553

NFGS Blinded Population Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A class detailing the NICHD Fetal Growth Study blinded population groups; the class contains exactly nine subclasses, one for each of blinded sites at which subjects were onboarded to the study.

NFGS Blinded Population Group #1
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #1
notation: HHEAR_554

NFGS Blinded Population Group #2
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #2
notation: HHEAR_555

NFGS Blinded Population Group #3
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #3
notation: HHEAR_556

NFGS Blinded Population Group #4
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #4
notation: HHEAR_557

NFGS Blinded Population Group #5
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #5
notation: HHEAR_558

NFGS Blinded Population Group #6
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #6
notation: HHEAR_559

NFGS Blinded Population Group #7
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #7
notation: HHEAR_560

NFGS Blinded Population Group #8
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #8
notation: HHEAR_561

NFGS Blinded Population Group #9
type: Class
subclass of: NFGS Blinded Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: NICHD Fetal Growth Study blinded population group #9
notation: HHEAR_562

Second Hand Smoke Exposure by Household Member
type: Class
subclass of: EFO_0008361
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A class used to indicate the level of second hand smoke exposure that occurs in a person's household

Second Hand Smoke Exposure by Location
type: Class
subclass of: EFO_0008361
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A class to indicate where a person was exposed to second hand smoke; subclasses of this class detail where a person may have been exposed to second hand smoke.

Seven Days Prior to Baseline
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: SIO_000668
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: Seven days prior to a study baseline

Count of Plastic Packaged Food Consumption
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats Food Packaged in Plastic
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A count of the number of times a person has consumed food packaged in plastic during a given time interval

Count of Plastic Packaged Beverage Consumption
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000215
  some values from: Drinks Beverage Packaged in Plastic
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A count of the number of times a person has consumed a beverage packaged in plastic during a given time interval

Count of Food or Beverage Reheated in Plastic Consumption
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000215
  some values from: Consumes Food Or Beverage Reheated in Plastic
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A count of the number of times a person has consumed a food or beverage that has been reheated in a plastic container during a given time interval

Count of Canned Food Consumption
type: Class
subclass of: food packaging
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats Canned Food
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A count of the number of times a person has consumed canned food in a given time interval

Spouse or Significant Other and Adult Child Living In Household Currently Smokes
type: Class
equivalent class: Class
  intersection of: Spouse or Significant Other Living In Household Currently Smokes
  intersection of: Adult Child Living In Household Currently Smokes
subclass of: Spouse or Significant Other Living In Household Currently Smokes
subclass of: Adult Child Living In Household Currently Smokes
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Spouse or Significant Other and Adult Child Living In Household Currently Smokes
notation: HHEAR_563

Spouse or Significant Other and Adult Child and Child Under 18 and Other Adults Living In Household Currently Smokes
type: Class
equivalent class: Class
  intersection of: Spouse or Significant Other Living In Household Currently Smokes
  intersection of: Child Under 18 Living In Household Currently Smokes
  intersection of: Adult Child Living In Household Currently Smokes
  intersection of: Other Adults Living In Household Currently Smoke
subclass of: Spouse or Significant Other Living In Household Currently Smokes
subclass of: Child Under 18 Living In Household Currently Smokes
subclass of: Adult Child Living In Household Currently Smokes
subclass of: Other Adults Living In Household Currently Smoke
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Spouse or Significant Other and Adult Child and Child Under 18 and Other Adults Living In Household Currently Smokes
notation: HHEAR_564

School Breakfast Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats School Breakfast
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A measure of the number of times in a given time interval that a person eats breakfast provided at school

School Lunch Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Eats School Lunch
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A measure of the number of times in a given time interval that a person eats lunch provided at school

Difference of Weights
type: Class
subclass of: Difference
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: body weight
    intersection of: Subtrahend
subclass of: Restriction
  on property: SIO_000008
  some values from: Class
    intersection of: body weight
    intersection of: Minuend
type: NamedIndividual
type: NodeShape
comment: The arithmetic difference of two weights

Duration of Breast Feeding
type: Class
subclass of: duration
subclass of: Diet and Nutrition
subclass of: Restriction
  on property: SIO_000215
  some values from: Breast Feeding
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a mother has spent breastfeeding a child

Milk Collection
type: Class
subclass of: Biospecimen Collection
type: NamedIndividual
type: NodeShape
comment: A time point after the birth of a child when a mother collects breast milk for analysis.

Less than 11th Grade
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The status of completing less than the 11th grade of school
notation: HHEAR_936

Not Frequently Exposed to Second Hand Smoke
type: Class
subclass of: Second Hand Smoke Exposure by Frequency
subclass of: Has Been Exposed to Second Hand Smoke
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Not Frequently Exposed to Second Hand Smoke
notation: HHEAR_569

Second Hand Smoke Exposure by Indicator Status
type: Class
subclass of: EFO_0008361
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A class to identify if a person has been exposed to second hand smoke or has not been exposed to second hand smoke during an implicit time period

Cigarettes Per Day Measurement - Asked During Pregnancy
type: Class
subclass of: EFO_0006525
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Cigarettes Per Day Measurement - Asked During Pregnancy

Cigarettes Per Day Measurement - Asked After Pregnancy
type: Class
subclass of: EFO_0006525
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Cigarettes Per Day Measurement - Asked After Pregnancy

Smoking Status - Asked During Pregnancy
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Smoking Status - Asked During Pregnancy

Smoking Status - Asked After Pregnancy
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Smoking Status - Asked After Pregnancy

Eclampsia or Severe Pre-eclampsia
type: Class
equivalent class: Class
  union of: severe pre-eclampsia
  union of: eclampsia
subclass of: pre-eclampsia
subclass of: Class
  union of: severe pre-eclampsia
  union of: eclampsia
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Eclampsia or Severe Pre-eclampsia
notation: HHEAR_578

Superimposed Pre-eclampsia
type: Class
subclass of: pre-eclampsia
type: NamedIndividual
type: NodeShape
comment: Superimposed preeclampsia refers to women with chronic arterial hypertension (primary or secondary) who develop preeclampsia (PE). Source: Guedes-Martins L. Superimposed Preeclampsia. Adv Exp Med Biol. 2017;956:409-417. doi: 10.1007/5584_2016_82. PMID: 27722963.

Superimposed, severe, or mild preeclampsia
type: Class
equivalent class: Class
  union of: DOID_10590
  union of: severe pre-eclampsia
  union of: Superimposed Pre-eclampsia
subclass of: pre-eclampsia
subclass of: Class
  union of: DOID_10590
  union of: severe pre-eclampsia
  union of: Superimposed Pre-eclampsia
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Superimposed, severe, or mild preeclampsia
notation: HHEAR_579

New Onset Antepartum Hypertension
type: Class
subclass of: antepartum hypertension
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes New Onset Antepartum Hypertension
notation: HHEAR_580

New Onset Postpartum Hypertension
type: Class
subclass of: postpartum hypertension
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes New Onset Postpartum Hypertension
notation: HHEAR_581

Indicated Birth
type: Class
subclass of: Non-spontaneous Birth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A birth in which medical intervention is necessitated by the medical condition of the mother or fetus.
notation: HHEAR_586

Non-spontaneous Birth
type: Class
equivalent class: Class
  complement of: Spontaneous Labor and Birth
subclass of: Birth Outcome
type: NamedIndividual
type: NodeShape
comment: The birth of a child that does not occur spontaneously; the birth may be initiated by or aided by some medical intervention.

Spontaneous Term Birth
type: Class
equivalent class: Class
  intersection of: Spontaneous Labor and Birth
  intersection of: Term Birth
subclass of: Spontaneous Labor and Birth
subclass of: Term Birth
subclass of: Class
  intersection of: Spontaneous Labor and Birth
  intersection of: Term Birth
type: NamedIndividual
type: NodeShape
comment: The birth of a child that occurs at term and without medical intervention

Non-spontaneous Term Birth
type: Class
equivalent class: Class
  intersection of: Term Birth
  intersection of: Non-spontaneous Birth
subclass of: Term Birth
subclass of: Non-spontaneous Birth
subclass of: Class
  intersection of: Term Birth
  intersection of: Non-spontaneous Birth
type: NamedIndividual
type: NodeShape
comment: The birth of a child that occurs at term and as the result of a medical intervention

Annual Income $25,000 to $29,999
type: Class
subclass of: Annual Income $25,000 to $34,999
subclass of: Annual Income $20,000 to $29,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 29999
subclass of: Restriction
  on property: minValue
  has value: 25000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $25,000 to $29,999
notation: HHEAR_592

Annual Income $50,000 to $59,999
type: Class
subclass of: Annual Income $50,000 to $74,999
subclass of: Annual Income $45,000 to $64,999
subclass of: Annual Income $40,000 to $60,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 59999
subclass of: Restriction
  on property: minValue
  has value: 50000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $50,000 to $59,999
notation: HHEAR_593

Annual Income $60,000 to $74,999
type: Class
subclass of: Annual Income $50,001 to $75,000
subclass of: Annual Income $50,000 to $74,999
subclass of: Annual Income $60,000 to $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 74999
subclass of: Restriction
  on property: minValue
  has value: 60000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $60,000 to $74,999
notation: HHEAR_594

Annual Income $100,000 to $149,999
type: Class
subclass of: Annual Income $100,000 to $199,999
subclass of: Annual Income $75,000 to $149,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 149999
subclass of: Restriction
  on property: minValue
  has value: 100000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $100,000 to $149,999
notation: HHEAR_595

Annual Income $150,000 to $199,999
type: Class
subclass of: Annual Income $100,000 to $199,999
subclass of: Annual Income More Than $125,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 199999
subclass of: Restriction
  on property: minValue
  has value: 150000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $150,000 to $199,999
notation: HHEAR_596

One Month Prior to Followup
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: A time interval that begins one month prior to a study follow-up and ends at the beginning of the study follow-up.

Connor Davidson Resilience Scale
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: "Resilience may be viewed as a measure of stress coping ability and, as such, could be an important target of treatment in anxiety, depression, and stress reactions. We describe a new rating scale to assess resilience. The Connor-Davidson Resilience scale (CD-RISC) comprises of 25 items, each rated on a 5-point scale (0–4), with higher scores reflecting greater resilience." Source: DEVELOPMENT OF A NEW RESILIENCE SCALE: THE CONNOR-DAVIDSON RESILIENCE SCALE (CD-RISC) Kathryn M. Connor, M.D., and Jonathan R.T. Davidson, M.D.

Multidimensional Scale of Perceived Social Support
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: Source: Zimet, G. D., Dahlem, N. W., Zimet, S. G., & Farley, G. K. (1988). The multidimensional scale of perceived social support. Journal of personality assessment, 52(1), 30-41.

Pregnancy Experience Scale
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: “The Pregnancy Experience Scale measures daily stressors women may experience during pregnancy (DiPietro et al., 2004). The brief version of the scale (PES-Brief) contains 20 items representing the most frequently endorsed hassles and uplifts from the 41-item original scale (DiPietro, Christensen, & Costigan, 2008). Each item is rated on a 4-point Likert scale with values of 0 to 3. The items are combined into a set of six scores: frequency of hassles,frequency of uplifts, intensity of hassles, intensity of uplifts, hassle:uplift frequency ratio, andhassle:uplift intensity ratio. DiPietro, Christensen, & Costigan (2008) reported that the hassleand uplift scales demonstrated acceptable internal consistency reliability with Cronbach’s alphasof 0.83 and 0.82, respectively. Test-retest reliability of the scales ranged from 0.63 to 0.73. ThePES-Brief scores were significantly correlated with the STAI, Center for Epidemiologic Studies-Depression scale (CES-D; Radloff, 1977), and the World Health Organization five-item wellbeingindex (WHO-5), supporting the convergent validity of the scale.” Source: DiPietro JA, Christensen AL, & Costigan KA (2008). The pregnancy experience scale-brief version. JPsychosom Obstet Gynaecol, 29(4), 262-267.

Krieger Racism Scale
type: Class
subclass of: Questionnaire
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: Instrument conceptualized as measuring self-report experiences of racial discrimination; Combines questions from multiple instruments including the Experiences of Discrimination questionnaire, Williams’ Major and Everyday Discrimination measures, a five-item social desirability scale and additional items on worries, global experiences and formal complaints of discrimination. Source: Krieger N, Smith K, Naishadham D, Hartman C, Barbeau EM. Experiences of discrimination: validity and reliability of a self-report measure for population health research on racism and health. Soc Sci Med. 2005 Oct;61(7):1576-96. doi: 10.1016/j.socscimed.2005.03.006. Epub 2005 Apr 21. PMID: 16005789.

Gestational Age From 20 to 28 Weeks
type: Class
subclass of: EFO_0005112
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The gestational age range of a fetus beginning at the start of week 20 and ending immediately before the beginning of week 28
notation: HHEAR_700

Gestational Age From 28 to 32 Weeks
type: Class
subclass of: EFO_0005112
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The gestational age range of a fetus beginning at the start of week 28 and ending immediately before the beginning of week 32
notation: HHEAR_588

Gestational Age From 32 to 34 Weeks
type: Class
subclass of: EFO_0005112
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The gestational age range of a fetus beginning at the start of week 32 and ending immediately before the beginning of week 34
notation: HHEAR_589

Gestational Age From 34 to 36 Weeks
type: Class
subclass of: EFO_0005112
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The gestational age range of a fetus beginning at the start of week 34 and ending immediately before the beginning of week 36
notation: HHEAR_590

Has Used Illegal Drugs or Non-Prescribed Pharmaceutical Drugs
type: Class
subclass of: Consumption of an Addictive Substance
subclass of: Drug History
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has used illegal drugs, or non-prescribed pharmaceutical drugs, either currently or in the past
notation: HHEAR_610

Associate's Degree
type: Class
subclass of: College Graduate
subclass of: Associate's Degree or Technical Degree
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Completed an associate's degree
notation: HHEAR_681

Associate's Degree or Technical Degree
type: Class
equivalent class: Class
  union of: Technical School
  union of: Associate's Degree
subclass of: Some College or Technical School
subclass of: Class
  union of: Technical School
  union of: Associate's Degree
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Completed either an associate's degree or a technical degree
notation: HHEAR_591

Recruited At Case Western Reserve University
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q1047060
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at Case Western Reserve University
notation: HHEAR_570

Recruited At Columbia University
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q49088
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at Columbia University
notation: HHEAR_571

Recruited At Indiana University
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q1079140
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at Indiana University
notation: HHEAR_696

Recruited At UPMC Magee-Womens Hospital
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q30253944
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at UPMC Magee-Womens Hospital
notation: HHEAR_699

Recruited At Northwestern University
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q309350
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at Northwestern University
notation: HHEAR_573

Recruited At University Of California, Irvine
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q868421
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at University of California, Irvine
notation: HHEAR_697

Recruited At University Of Pennsylvania
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q49117
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at University of Pennsylvania
notation: HHEAR_698

Recruited At University Of Utah
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q168515
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited at University of Utah
notation: HHEAR_597

Frequency Composite Score
type: Class
subclass of: Composite Score
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A score that is the composite, summation, or aggregation of multiple frequency measurements

Intensity Composite Score
type: Class
subclass of: Composite Score
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A score that is the composite, summation, or aggregation of multiple measurements of intensity

Childhood Followup 3
type: Class
subclass of: Study Followup 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Childhood Period
definition: A point in a study that occurs after the second follow-up point in the study and occurs during the study subject's childhood period.

Childhood Followup 4
type: Class
subclass of: Study Followup 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the third follow-up point in the study and occurs during the study subject's childhood period.

Childhood Followup 5
type: Class
subclass of: Study Followup 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the fourth follow-up point in the study and occurs during the study subject's childhood period.

Childhood Followup 6
type: Class
subclass of: Study Followup 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the fifth follow-up point in the study and occurs during the study subject's childhood period.

Childhood Followup 7
type: Class
subclass of: Study Followup 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the sixth follow-up point in the study and occurs during the study subject's childhood period.

Childhood Followup 8
type: Class
subclass of: Study Followup 8
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
subclass of: Restriction
  on property: SIO_000668
  all values from: Childhood Period
definition: A point in a study that occurs after the seventh follow-up point in the study and occurs during the study subject's childhood period.

Islet Autoimmunity
type: Class
subclass of: autoimmune disease of endocrine system
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Persistent Islet Autoimmunity (or any IA) was defined as confirmed positive insulin autoantibodies (IAAs), GAD antibody (GADA), specifically to isoform GAD65, or insulinoma antigen-2 autoantibody, which were analyzed by radiobinding assays (25,26) on at least two consecutive study visits.
notation: HHEAR_643

Type 1 Diabetes and Islet Autoimmunity
type: Class
equivalent class: Class
  intersection of: type 1 diabetes mellitus
  intersection of: Islet Autoimmunity
subclass of: type 1 diabetes mellitus
subclass of: Islet Autoimmunity
subclass of: Class
  intersection of: type 1 diabetes mellitus
  intersection of: Islet Autoimmunity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The condition of having both Type 1 Diabetes Mellitus and Islet Autoimmunity disease
notation: HHEAR_644

Recruited In Colorado
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q1261
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Colorado
notation: HHEAR_695

Recruited In Georgia or Florida
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Class
  union of: Restriction
    on property: SIO_000668
    has value: Q1428
  union of: Restriction
    on property: SIO_000668
    has value: Q812
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in either Georgia or Florida
notation: HHEAR_598

Recruited In Washington State
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q1223
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Washington State
notation: HHEAR_599

Recruited In Finland
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q33
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Finland
notation: HHEAR_600

Recruited In Germany
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q183
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Germany
notation: HHEAR_601

Recruited In Sweden
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q34
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Sweden
notation: HHEAR_602

Post-Birth Up To 27 Days
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: A time period that begins immediately after birth and ends at the end of the 27th day after birth

Post-Birth 28 Days Or More
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: A time interval that begins at the beginning of the 28th day after birth

Uses Probiotic Supplement
type: Class
subclass of: nutrition intake
subclass of: Exposed to Probiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: Probiotic
disjoint with: Does Not Use Probiotic Supplements
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Probiotic Supplement
notation: HHEAR_603

Some Technical School
type: Class
subclass of: Some College or Technical School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has attended some, but has not completed, technical school
notation: HHEAR_604

Technical School Graduate
type: Class
subclass of: Technical School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A graduate of a technical school
notation: HHEAR_605

Some Trade School
type: Class
subclass of: Education
disjoint with: Trade School Graduate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has attended some trade school, but has not graduated from trade school
notation: HHEAR_606

Completed Primary School and Some Trade School
type: Class
subclass of: Some Trade School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has completed primary school and has attended some trade school, but has not graduated
notation: HHEAR_607

Trade School Graduate
type: Class
subclass of: Some College or Trade School Graduate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Graduated from a trade school
notation: HHEAR_608

College Graduate or Higher
type: Class
subclass of: Post-Secondary Education
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A graduate of a college or university, or of a higher graduate degree
notation: HHEAR_645

Some College or Trade School Graduate
type: Class
equivalent class: Class
  union of: Some College
  union of: Trade School Graduate
subclass of: Education
subclass of: Class
  union of: Some College
  union of: Trade School Graduate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Someone who graduated from trade school or attended some college
notation: HHEAR_646

Second or Third Trimester
type: Class
subclass of: From Conception
subclass of: SIO_000417
subclass of: Restriction
  on property: SIO_000668
  all values from: Class
    intersection of: Conceiving
definition: The time period from pregnancy week 13 through 40.

A minor allele for rs689
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs689
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs689
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs689

G minor allele for rs231775
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs231775
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs231775
type: NamedIndividual
type: NodeShape
comment: This class denotes G minor allele for rs231775

A minor allele for rs2476601
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs2476601
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs2476601
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs2476601

C minor allele for rs2816316
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs2816316
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs2816316
type: NamedIndividual
type: NodeShape
comment: This class denotes C minor allele for rs2816316

A minor allele for rs10517086
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs10517086
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs10517086
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs10517086

A minor allele for rs4948088
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs4948088
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs4948088
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs4948088

A minor allele for rs2292239
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs2292239
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs2292239
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs2292239

A minor allele for rs3184504
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs3184504
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs3184504
type: NamedIndividual
type: NodeShape
comment: This class denotes A minor allele for rs3184504

G minor allele for rs12708716
type: Class
equivalent class: Class
  intersection of: minor polymorphic allele
  intersection of: Restriction
    on property: SIO_000272
    some values from: rs12708716
subclass of: minor polymorphic allele
subclass of: Restriction
  on property: SIO_000272
  some values from: rs12708716
type: NamedIndividual
type: NodeShape
comment: This class denotes G minor allele for rs12708716

Number of A minor alleles for rs689
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs689
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs689

Number of G minor alleles for rs231775
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: G minor allele for rs231775
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of G minor alleles for rs231775

Number of A minor alleles for rs2476601
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs2476601
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs2476601

Number of C minor alleles for rs2816316
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: C minor allele for rs2816316
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of C minor alleles for rs2816316

Number of A minor alleles for rs10517086
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs10517086
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs10517086

Number of A minor alleles for rs4948088
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs4948088
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs4948088

Number of A minor alleles for rs2292239
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs2292239
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs2292239

Number of A minor alleles for rs3184504
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: A minor allele for rs3184504
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs3184504

Number of G minor alleles for rs12708716
type: Class
subclass of: Number of Minor Alleles for SNP
subclass of: Restriction
  on property: SIO_000215
  some values from: G minor allele for rs12708716
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of G minor alleles for rs12708716

Family History of Type 1 Diabetes Mellitus
type: Class
subclass of: Family history
subclass of: Restriction
  on property: SIO_000668
  some values from: type 1 diabetes mellitus
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has family history of Type 1 Diabetes Mellitus
notation: HHEAR_611

DR4*030X/0302*DR3*0501/0201
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR3*0501/0201
notation: HHEAR_616

DR4*030X/0302*DR4*030X/0302
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR4*030X/0302
notation: HHEAR_618

DR4*030X/0302*DR4*030X/020X
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR4*030X/020X
notation: HHEAR_617

DR4*030X/0302*DR8*0401/0402
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR8*0401/0402
notation: HHEAR_620

DR4*030X/0302*DR1*0101/0501
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR1*0101/0501
notation: HHEAR_614

DR4*030X/0302*DR13*0102/0604
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR13*0102/0604
notation: HHEAR_615

DR4*030X/0302*DR4*030X/0304
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR4*030X/0304
notation: HHEAR_619

DR4*030X/0302*DR9*030X/0303
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR4*030X/0302*DR9*030X/0303
notation: HHEAR_621

DR3*0501/0201*DR3*0501/0201
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR3*0501/0201*DR3*0501/0201
notation: HHEAR_612

DR3*0501/0201*DR9*030X/0303
type: Class
subclass of: HLA Complex
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes DR3*0501/0201*DR9*030X/0303
notation: HHEAR_613

Number of A minor alleles for rs2476601 genotyped by the TEDDY HLA Lab
type: Class
subclass of: Number of A minor alleles for rs2476601
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs2476601 genotyped by the TEDDY HLA Lab

Number of A minor alleles for rs2476601 genotyped on the Illumina Immunochip
type: Class
subclass of: Number of A minor alleles for rs2476601
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of A minor alleles for rs2476601 genotyped on the Illumina Immunochip

Perenteryl
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Vivera
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Vintix
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Bio-flora
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Lactil
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Biogaia
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Biolactus
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Multiflora
type: Class
subclass of: Probiotic
type: NamedIndividual
type: NodeShape
comment: A name brand probiotic supplement

Uses Perenteryl
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Perenteryl
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Perenteryl
notation: HHEAR_622

Uses Vivera
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Vivera
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Vivera
notation: HHEAR_623

Uses Vintix
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Vintix
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Vintix
notation: HHEAR_624

Uses Bio-flora
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Bio-flora
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Bio-flora
notation: HHEAR_625

Uses Lactil
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Lactil
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Lactil
notation: HHEAR_626

Uses Biogaia
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Biogaia
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Biogaia
notation: HHEAR_627

Uses Biolactus
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Biolactus
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Biolactus
notation: HHEAR_628

Uses Multiflora
type: Class
subclass of: Uses Probiotic Supplement
subclass of: Restriction
  on property: SIO_000139
  some values from: Multiflora
type: NamedIndividual
type: Quality Value
comment: This class denotes Uses Multiflora
notation: HHEAR_629

Does Not Use Probiotic Supplements
type: Class
subclass of: nutrition intake
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Does not (currently or during a specified time period) use a probiotic supplement
notation: HHEAR_630

Uses Amoxicillin
type: Class
subclass of: Uses Antibiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: amoxicillin
type: NamedIndividual
type: Quality Value
definition: Has used or uses amoxicillin
notation: HHEAR_631

Uses Penicillin
type: Class
subclass of: Uses Antibiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: penicillin
type: NamedIndividual
type: Quality Value
definition: Has used or uses penicillin
notation: HHEAR_632

Uses Cloxacillin
type: Class
subclass of: Uses Antibiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: cloxacillin
type: NamedIndividual
type: Quality Value
definition: Has used or uses cloxacillin
notation: HHEAR_633

Uses Erythromycin A
type: Class
subclass of: Uses Antibiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: erythromycin A
type: NamedIndividual
type: Quality Value
definition: Has used or uses erythromycin A
notation: HHEAR_634

Uses Azithromycin
type: Class
subclass of: Uses Antibiotics
subclass of: Restriction
  on property: SIO_000139
  some values from: azithromycin
type: NamedIndividual
type: Quality Value
definition: Has used or uses azithromycin
notation: HHEAR_635

kilocalories per day
type: Class
subclass of: rate unit
type: NamedIndividual
type: SIO_000074
comment: This class denotes kilocalories per day
notation: kcal/day

One Year After Menarche
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalAfter
  some values from: Menarche
type: NamedIndividual
type: NodeShape
comment: A time interval that begins one year after menarche

Two Years After Menarche
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalAfter
  some values from: Menarche
type: NamedIndividual
type: NodeShape
comment: A time interval that begins two years after menarche

Probiotic Beverage
type: Class
equivalent class: Class
  intersection of: beverage
  intersection of: Restriction
    on property: SIO_000139
    some values from: Probiotic
subclass of: beverage
subclass of: Restriction
  on property: SIO_000139
  some values from: Probiotic
type: NamedIndividual
type: NodeShape
comment: A beverage that contains probiotics

Drinks Probiotic Beverage
type: Class
subclass of: Environmental Exposure
subclass of: Eating or Drinking
subclass of: Restriction
  on property: SIO_000230
  some values from: Probiotic Beverage
type: NamedIndividual
type: NodeShape
comment: The act of drinking a probiotic beverage

Probiotic Beverage Consumption Frequency
type: Class
subclass of: Diet Quantity
subclass of: SIO_001367
subclass of: Restriction
  on property: SIO_000215
  some values from: Drinks Probiotic Beverage
type: NamedIndividual
type: Quality Variable
definition: Frequency of Probiotic Beverage Consumption.

Finished Primary School
type: Class
subclass of: Finished Elementary School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has completed primary school education level
notation: HHEAR_638

Total Breast Volume
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000049
subclass of: Restriction
  on property: SIO_000215
  some values from: Mammary Gland Tissue
subclass of: Restriction
  on property: SIO_000215
  some values from: UBERON_0000310
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total volume of a human breast

Breast Fibroglandular Tissue Volume
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000049
subclass of: Restriction
  on property: SIO_000215
  some values from: Breast Fibroglandular Tissue
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The volume of a human breast's fibroglandular tissue

Percentage of Fibroglandular Volume
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_001413
subclass of: Restriction
  on property: STATO_0000101
  some values from: Breast Fibroglandular Tissue Volume
subclass of: Restriction
  on property: STATO_0000259
  some values from: Total Breast Volume
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The ratio of a breast's fibroglandular volume to its total breast tissue volume, expressed as a percentage

Total Breast Area
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_001407
subclass of: Restriction
  on property: SIO_000215
  some values from: UBERON_0000310
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total surface area of a human breast

Has Provided a Stool Sample
type: Class
subclass of: Measurement
disjoint with: Has Not Provided a Stool Sample
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A subject has provided a stool sample for analysis
notation: HHEAR_636

Has Not Provided a Stool Sample
type: Class
subclass of: Measurement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A subject has not provided a stool sample for analysis.
notation: HHEAR_637

Study Followup 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup
definition: A point in a study where data is gathered after the first study followup.

Study Followup 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2
definition: A point in a study where data is gathered after the second study followup.

Study Followup 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3
definition: A point in a study where data is gathered after the third study followup.

Study Followup 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4
definition: A point in a study where data is gathered after the fourth study followup.

Study Followup 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 5
definition: A point in a study where data is gathered after the fifth study followup.

Study Followup 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 6
definition: A point in a study where data is gathered after the sixth study followup.

Study Followup 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 7
definition: A point in a study where data is gathered after the seventh study followup.

Maternal Antibody
type: Class
subclass of: SIO_010465
type: NamedIndividual
type: NodeShape
comment: Maternal antibodies are transferred from mother to child and protect neonates and infants during the time of maturation of their immune system. The vast majority of maternal antibodies are of the IgG isotype. Source: Niewiesk S. Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies. Front Immunol. 2014 Sep 16;5:446. doi: 10.3389/fimmu.2014.00446. PMID: 25278941; PMCID: PMC4165321.

Exposure to Maternal Antibodies
type: Class
subclass of: EFO_0000487
subclass of: Restriction
  on property: SIO_000139
  some values from: Maternal Antibody
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes exposure to maternal antibodies
notation: HHEAR_639

Asian and White
type: Class
subclass of: Asian
subclass of: White
subclass of: Multiracial
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A multiracial race category indicating that a subject identifies as both Asian and White
notation: HHEAR_640

Black and White
type: Class
subclass of: Black or African American
subclass of: White
subclass of: Multiracial
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A multiracial race category indicating that a subject identifies as both Black (African American) and White
notation: HHEAR_641

Number of Minor Alleles for SNP
type: Class
subclass of: Medical History
subclass of: SIO_000794
type: NamedIndividual
type: NodeShape
comment: The measured count of a specific minor allele for a single nucleotide polymorphism of a gene variant

Imputed Measurement
type: Class
subclass of: Measurement
disjoint with: Direct Measurement
type: NamedIndividual
type: NodeShape
comment: An imputed, or inferred measurement one where an assumed value given to an item when the actual value is not known or available. The value may be determined by applying a standard scale or algorithm to other measurements that can be used to estimate the true value of the measurement.

Direct Measurement
type: Class
subclass of: Measurement
type: NamedIndividual
type: NodeShape
comment: A direct measurement is taken when one explicitly measures the desired characteristic or quantity of the object in question. This in comparison to an imputed, or indirect measurement where the measurement value is determined by measuring some other characteristic or quantity and applying a scale or algorithm to infer an estimated value of the desired quantity.

One Month Prior to Followup 2
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: A time interval that begins one month prior to a study's second follow-up and ends at the beginning of the study's second follow-up.

One Month Prior to Baseline
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalContains
  some values from: Two Weeks Prior to Childhood Baseline
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: A time interval that begins one month prior to a study baseline and ends at the beginning of the study baseline.

Exposed to Probiotics
type: Class
subclass of: EFO_0000487
subclass of: Restriction
  on property: SIO_000139
  some values from: Probiotic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Exposure to probiotics, either through directly ingesting them or through other means
notation: HHEAR_642

Z-Score For Fixed Age and Sex
type: Class
subclass of: Z-Score
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_001013
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_010029
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A Z-score computation from a population which all share the same age range and sex assignment

Z-Score For Fixed Height and Sex
type: Class
subclass of: Z-Score
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_000040
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_010029
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A Z-score computation from a population which all share the same height range and sex assignment

Biospecimen Collection
type: Class
subclass of: Sample Collection
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: RO_0004009
  some values from: Biospecimen
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: An event in which a biospecimen is collected in order to be measured or analyzed

Stool Sample Collection
type: Class
subclass of: Biospecimen Collection
subclass of: Restriction
  on property: RO_0004009
  some values from: Stool Sample
type: NamedIndividual
type: NodeShape
comment: An event in which a stool sample is collected in order to be measured or analyzed

Five Months Prior to Followup 4
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: A time interval that begins five months prior to a study's fourth follow-up and ends at the beginning of the study's fourth follow-up.

Six Months Prior to Followup 4
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalContains
  some values from: Five Months Prior to Followup 4
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: A time interval that begins six months prior to a study's fourth follow-up and ends at the beginning of the study's fourth follow-up.

Does Not Use Antibiotics
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject does not currently (or during a specified time period) use antibiotics
notation: HHEAR_647

Does Not Breastfeed
type: Class
subclass of: Feeding Method
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a mother does not currently (or during a specified period of time) breastfeed her child.
notation: HHEAR_648

Received Special Education
type: Class
subclass of: Education
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject received special education.
notation: HHEAR_649

Total Cholesterol
type: Class
subclass of: cholesterol
subclass of: Restriction
  on property: BFO_0000051
  some values from: very-low-density lipoprotein cholesterol
subclass of: Restriction
  on property: BFO_0000051
  some values from: low-density lipoprotein cholesterol
subclass of: Restriction
  on property: BFO_0000051
  some values from: high-density lipoprotein cholesterol
type: NamedIndividual
type: NodeShape
comment: The mereological sum of all three cholesterols, VLDL, LDL, and HDL
notation: CHOL

Tanner Scale For Breast Development (Assigned By Child)
type: Class
subclass of: Tanner Scale For Breast Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Breast Development as assigned by the child

Tanner Scale For Genital Development (Assigned By Child)
type: Class
subclass of: Tanner Scale For Genital Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Genital Development as assigned by the child

Tanner Scale For Female Pubic Hair Development (Assigned By Child)
type: Class
subclass of: Tanner Scale For Female Pubic Hair Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Female Pubic Hair Development as assigned by the child

Tanner Scale For Male Pubic Hair Development (Assigned By Child)
type: Class
subclass of: Tanner Scale For Male Pubic Hair Development
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A rating of the Tanner Scale for Male Pubic Hair Development as assigned by the child

Pre-Menarche
type: Class
subclass of: Life Stage
subclass of: Restriction
  on property: intervalMeets
  some values from: Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The time period for a child that ends at the onset of menarche.
notation: HHEAR_676

Post-Menarche
type: Class
subclass of: Life Stage
subclass of: Restriction
  on property: intervalMetBy
  some values from: Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The time period for a child that begins at the ending of menarche.
notation: HHEAR_675

Estimated Body Fat Percentage
type: Class
subclass of: Imputed Measurement
subclass of: SIO_001413
subclass of: Restriction
  on property: SIO_000283
  some values from: CMO_0000302
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: An estimated measure of body fat percentage

Age at Formula Introduction
type: Class
subclass of: Diet and Nutrition
subclass of: SIO_001013
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The age at which an infant is first given artificial formula instead of breast milk

Consumed beverages containing probiotics 1 or 2 days per week
type: Class
subclass of: Probiotic Beverage Consumption Frequency
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 1
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 2
subclass of: Restriction
  on property: SIO_000221
  has value: days per week
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Consumed beverages containing probiotics 1 or 2 days per week
notation: HHEAR_650

Consumed beverages containing probiotics 3 or 4 days per week
type: Class
subclass of: Probiotic Beverage Consumption Frequency
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 3
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 4
subclass of: Restriction
  on property: SIO_000221
  has value: days per week
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Consumed beverages containing probiotics 3 or 4 days per week
notation: HHEAR_651

Consumed beverages containing probiotics 5 or 6 days per week
type: Class
subclass of: Probiotic Beverage Consumption Frequency
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 5
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 6
subclass of: Restriction
  on property: SIO_000221
  has value: days per week
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Consumed beverages containing probiotics 5 or 6 days per week
notation: HHEAR_652

Consumed beverages containing probiotics all days of the week
type: Class
subclass of: Probiotic Beverage Consumption Frequency
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001113
    intersection of: Restriction
      on property: SIO_000300
      has value: 7
subclass of: Restriction
  on property: SIO_000216
  some values from: Class
    intersection of: SIO_001114
    intersection of: Restriction
      on property: SIO_000300
      has value: 7
subclass of: Restriction
  on property: SIO_000221
  has value: days per week
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Consumed beverages containing probiotics all days of the week
notation: HHEAR_653

Other Female Relative
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female relative that is not a mother, aunt, cousin, or grandmother.
notation: HHEAR_662

Other Male Relative
type: Class
subclass of: Relative
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male relative that is not a father, uncle, cousin, or grandfather.
notation: HHEAR_663

Other Unrelated Female
type: Class
subclass of: SIO_000016
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A female that has a role as a caregiver for a subject but is not related to the subject.
notation: HHEAR_664

Other Unrelated Male
type: Class
subclass of: SIO_000016
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A male that has a role as a caregiver for a subject but is not related to the subject.
notation: HHEAR_665

Annual Income $35,000 to $49,999
type: Class
subclass of: Annual Income $30,001 to $50,000
subclass of: Annual Income $30,000 to $49,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 49999
subclass of: Restriction
  on property: minValue
  has value: 35000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $35,000 to $49,999
notation: HHEAR_666

Annual Income $75,000 to $149,999
type: Class
subclass of: Annual Income More Than $70,001
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 149999
subclass of: Restriction
  on property: minValue
  has value: 75000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $75,000 to $149,999
notation: HHEAR_667

Number of Adults in Household
type: Class
subclass of: Number of Members in Household
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Adults in Household

Number of Children in Household
type: Class
subclass of: Number of Members in Household
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Children in Household

Kaiser Permanente Insurance
type: Class
subclass of: Private Insurance
disjoint with: Private Insurance Other Than Kaiser Permanente
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Kaiser Permanente Insurance
notation: HHEAR_668

Duration of Domicile in United States
type: Class
subclass of: duration
subclass of: Demographic
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The length of time a person has lived in the United States

Private Insurance Other Than Kaiser Permanente
type: Class
equivalent class: Class
  intersection of: Private Insurance
  intersection of: Class
    complement of: Kaiser Permanente Insurance
subclass of: Private Insurance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Private Insurance Other Than Kaiser Permanente
notation: HHEAR_669

Children's Depression Inventory
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: This class denotes Children's Depression Inventory

Z-Score For Fixed Gestational Age and Sex
type: Class
subclass of: Z-Score
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_010029
subclass of: Restriction
  on property: RO_0000079
  some values from: EFO_0005112
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A Z-score computation from a population which all share the same gestational age range and sex assignment

Observational Cohort Study
type: Class
subclass of: SIO_001066
comment: This class denotes Observational Cohort Study

Observational Case-Control Study
type: Class
subclass of: SIO_001066
comment: This class denotes Observational Case-Control Study

Observational Case-Cohort Study
type: Class
subclass of: SIO_001066
comment: This class denotes Observational Case-Cohort Study

Observational Case Only Study
type: Class
subclass of: SIO_001066
comment: This class denotes Observational Case Only Study

Observational Cross-Sectional Study
type: Class
subclass of: SIO_001066
comment: This class denotes Observational Cross-Sectional Study

Experimental/RCT Study
type: Class
subclass of: SIO_001066
comment: This class denotes Experimental/RCT Study

Occupation Based Selection Criterion
type: Class
subclass of: selection criterion
type: NamedIndividual
type: NodeShape
comment: This class denotes Occupation Based Selection Criterion

Population Based Selection Criterion
type: Class
subclass of: selection criterion
type: NamedIndividual
type: NodeShape
comment: This class denotes Population Based Selection Criterion

Clinic Based Selection Criterion
type: Class
subclass of: selection criterion
type: NamedIndividual
type: NodeShape
comment: This class denotes Clinic Based Selection Criterion

School Based Selection Criterion
type: Class
subclass of: selection criterion
type: NamedIndividual
type: NodeShape
comment: This class denotes School Based Selection Criterion

Post-Menopause
type: Class
subclass of: Postmenopausal
subclass of: Life Stage
subclass of: Restriction
  on property: intervalMetBy
  some values from: Menopause
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The time period that begins after the onset of menopause
notation: HHEAR_1118

Late Adulthood
type: Class
subclass of: Adult
type: NamedIndividual
type: NodeShape
comment: The life stage that begins when a person is 65 years old

Percentile For Fixed Age and Sex
type: Class
subclass of: percentile
subclass of: Anthropometry
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_001013
subclass of: Restriction
  on property: RO_0000079
  some values from: SIO_010029
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A percentile computation from a population which all share the same age range and sex assignment

Organophosphorus Flame Retardant
type: Class
subclass of: flame retardant
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Organophosphorus Flame Retardant
notation: UOPFR

Oxidative Stress Marker
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Oxidative Stress Marker
notation: OXID

Universal Pesticide Metabolite in Urine
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Universal Pesticide Metabolite in Urine
notation: UPEST2

Organochlorine Pesticide
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Organochlorine Pesticide
notation: SOC

blood c-reactive protein level by high sensitivity measurement
type: Class
subclass of: blood C-reactive protein level
subclass of: Restriction
  on property: SIO_001157
  some values from: High Sensitivity C-Reactive Protein Measurement
type: NamedIndividual
type: NodeShape
comment: This class denotes blood c-reactive protein level by high sensitivity measurement

Male Caregiver
type: Class
subclass of: Caregiver
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010048
type: NamedIndividual
type: NodeShape
comment: A caregiver that identifies as male

Female Caregiver
type: Class
subclass of: Caregiver
subclass of: Restriction
  on property: SIO_000227
  all values from: Restriction
    on property: SIO_000008
    some values from: SIO_010052
type: NamedIndividual
type: NodeShape
comment: A caregiver that identifies as female

Trans-generational
type: Class
subclass of: Life Stage
type: NamedIndividual
type: NodeShape
comment: This class denotes Trans-generational

MMM Intervention Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A group or cohort who are included in a multi-component, multi-level, multi-setting intervention
notation: HHEAR_722

Perfluorooctanoic acid (linear isomer only)
type: Class
subclass of: Perfluorooctanoic acid
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Perfluorooctanoic acid (linear isomer only)
notation: NPFOA

Perfluorooctanoic acid (sum of branched isomers)
type: Class
subclass of: Perfluorooctanoic acid
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Perfluorooctanoic acid (sum of branched isomers)
notation: SBPFOA

Perfluorooctanesulfonic acid (linear isomer only)
type: Class
subclass of: Perfluorooctanesulfonic acid
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Perfluorooctanesulfonic acid (linear isomer only)
notation: NPFOS

Perfluorooctanesulfonic acid (sum of branched isomers)
type: Class
subclass of: Perfluorooctanesulfonic acid
type: NamedIndividual
type: NodeShape
comment: This class denotes Perfluorooctanesulfonic acid (sum of branched isomers)
notation: SBPFOS

Phenol
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Phenol
notation: UPHENOL

Trace Elements
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes the HHEAR chemical group Trace Elements
notation: TE

Urinary Dilution Factor
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Urinary Dilution Factor
notation: UDILUTE

Inflammatory Marker
type: Class
subclass of: biomarker
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Inflammatory Marker
notation: INFLAM

Nutrient
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Nutrient
notation: NUTR

Lipid in Blood
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Lipid in Blood
notation: BLIPID

Psychosocial Stress Marker
type: Class
subclass of: Targeted Analyte
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Psychosocial Stress Marker
notation: STRESS

Cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
type: Class
subclass of: 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
notation: CDCCA

Trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
type: Class
subclass of: 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
notation: TDCCA

Cohort Group 1
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Cohort group 1 for the "Sex-Specific Omics Profiles Related to Toxicant Exposures in Children" study conducted by Wei Perng, University of Michigan School of Public Health
notation: HHEAR_701

Cohort Group 2A
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Cohort group 2A for the "Sex-Specific Omics Profiles Related to Toxicant Exposures in Children" study conducted by Wei Perng, University of Michigan School of Public Health
notation: HHEAR_702

Cohort Group 2B
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Cohort group 2B for the "Sex-Specific Omics Profiles Related to Toxicant Exposures in Children" study conducted by Wei Perng, University of Michigan School of Public Health
notation: HHEAR_1201

Cohort Group 3
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Cohort group 3 for the "Sex-Specific Omics Profiles Related to Toxicant Exposures in Children" study conducted by Wei Perng, University of Michigan School of Public Health
notation: HHEAR_704

Dibutyl phosphate + Di-isobutyl phosphate
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/7881
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/80550
subclass of: Organophosphorus Flame Retardant
subclass of: Class
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/7881
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/80550
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: A substance that contains both Dibutyl phosphate and Di-isobutyl phosphate as its constituent parts
notation: DBUP_DIBP

tri-n-butyl phosphate/tri-iso-butyl phosphate
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: SIO_000028
    some values from: tributyl phosphate
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/31355
subclass of: Organophosphorus Flame Retardant
subclass of: Class
  intersection of: Restriction
    on property: SIO_000028
    some values from: tributyl phosphate
  intersection of: Restriction
    on property: SIO_000028
    some values from: http://rdf.ncbi.nlm.nih.gov/pubchem/compound/31355
type: NamedIndividual
type: NodeShape
comment: This class denotes tri-n-butyl phosphate/tri-iso-butyl phosphate

Ages and Stages Questionnaire
type: Class
subclass of: Questionnaire
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: This class denotes the Ages and Stages Questionnaire. Reference: https://agesandstages.com/

Ages and Stages Fine Motor Questionnaire
type: Class
subclass of: Ages and Stages Questionnaire
type: NamedIndividual
type: NodeShape
comment: The "fine motor" section of the Ages and Stages Questionnaire.

Ages and Stages Gross Motor Questionnaire
type: Class
subclass of: Ages and Stages Questionnaire
type: NamedIndividual
type: NodeShape
comment: The "gross motor" section of the Ages and Stages Questionnaire

Ages and Stages Personal Social Questionnaire
type: Class
subclass of: Ages and Stages Questionnaire
type: NamedIndividual
type: NodeShape
comment: The "personal social" section of the Ages and Stages Questionnaire

Ages and Stages Problem Solving Questionnaire
type: Class
subclass of: Ages and Stages Questionnaire
type: NamedIndividual
type: NodeShape
comment: The "problem solving" section of the Ages and Stages Questionnaire

Housing Assistance
type: Class
subclass of: Public Assistance
type: NamedIndividual
type: NodeShape
comment: This class denotes Housing Assistance

Income Assistance
type: Class
subclass of: Public Assistance
type: NamedIndividual
type: NodeShape
comment: This class denotes Income Assistance

Utility Assistance
type: Class
subclass of: Public Assistance
type: NamedIndividual
type: NodeShape
comment: This class denotes Utility Assistance

Urine Collection
type: Class
subclass of: Biospecimen Collection
subclass of: Restriction
  on property: RO_0004009
  some values from: urine
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An event in which urine is collected in order to be measured or analyzed
notation: HHEAR_924

Prenatal Questionnaire (PNQ)
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: The Prenatal Questionnaire (PNQ) was adapted from the Self-Administered Questionnaire (SAQ) developed within the Indian Health Service in 1997 [14] to meet the special needs of the Northern Plains Indians. The 36 items included in the PNQ queries the extent of alcohol use before and during pregnancy, along with the potential risk factors and demographic information. Source: Leonardson, G.R., Loudenburg, R. & Struck, J. Factors predictive of alcohol use during pregnancy in three rural states. Behav Brain Funct 3, 8 (2007). https://doi.org/10.1186/1744-9081-3-8

Adjusted Score
type: Class
subclass of: score
type: NamedIndividual
type: NodeShape
comment: A single score that is derived from a test or an observation and that has been transformed or altered.

Vitamin D Intervention Group
type: Class
subclass of: Experimental Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Vitamin D Intervention Group
notation: HHEAR_720

Ages and Stages Adjusted Score
type: Class
subclass of: Adjusted Score
type: NamedIndividual
type: NodeShape
comment: An adjusted score of an Ages and Stages Questionnaire response, where the derivation is the one documented in this reference: https://www.michaeltaymormd.com/storage/app/media/forms/master-set-asq.pdf

Physician Diagnosed Asthma With Medication or Wheezing
type: Class
subclass of: childhood-onset asthma
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Report of physician-diagnosed asthma at any time in the first 6 years of life, PLUS after the 5th birthday a) report of child’s use of any asthma medication OR b) report of wheeze
notation: HHEAR_721

Pediatric Eczema With Itchy Rash
type: Class
subclass of: Eczema
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Positive response to "...has a health care provider said that [CHILD] has eczema?" at any time from birth through age 6, PLUS positive response to "...itchy rash which was coming and going but did not completely get better?"
notation: HHEAR_714

Pediatric Allergic Rhinitis Before Age Six
type: Class
subclass of: Allergic rhinitis
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Positive response from birth through age 6 to the question "...has a health care provider said that [CHILD] has hay fever, allergic rhinitis, or allergies involving the eyes or nose?"
notation: HHEAR_715

Pediatric Food Allergy
type: Class
subclass of: food allergy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Positive response from birth through age 6 to the question "...has a health care provider said that [CHILD] has food allergies?"
notation: HHEAR_716

Receives Public Assistance
type: Class
subclass of: Public Assistance Status
subclass of: Restriction
  on property: SIO_000230
  some values from: Public Assistance
disjoint with: Does Not Receive Public Assistance
type: NamedIndividual
type: NodeShape
comment: This class denotes Receives Public Assistance

Receives Food Assistance
type: Class
subclass of: Receives Public Assistance
subclass of: Restriction
  on property: SIO_000230
  some values from: Food Assistance
disjoint with: Does Not Receive Food Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Receives Food Assistance
notation: HHEAR_705

Receives Housing Assistance
type: Class
subclass of: Receives Public Assistance
subclass of: Restriction
  on property: SIO_000230
  some values from: Housing Assistance
disjoint with: Does Not Receive Housing Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Receives Housing Assistance
notation: HHEAR_706

Receives Income Assistance
type: Class
subclass of: Receives Public Assistance
subclass of: Restriction
  on property: SIO_000230
  some values from: Income Assistance
disjoint with: Does Not Receive Income Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Receives Income Assistance
notation: HHEAR_707

Receives Utility Assistance
type: Class
subclass of: Receives Public Assistance
subclass of: Restriction
  on property: SIO_000230
  some values from: Utility Assistance
disjoint with: Does Not Receive Utility Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Receives Utility Assistance
notation: HHEAR_708

Population Group by Randomization
type: Class
subclass of: Population Group
type: NamedIndividual
type: NodeShape
comment: This class denotes Population Group by Randomization

Population Group by Study Site
type: Class
subclass of: Population Group
type: NamedIndividual
type: NodeShape
comment: This class denotes Population Group by Study Site

Public Assistance Status
type: Class
subclass of: Socioeconomic Status
subclass of: Activity
type: NamedIndividual
type: Facet
type: NodeShape
comment: A class that differentiates if someone receives some sort of public assistance or not

Does Not Receive Public Assistance
type: Class
subclass of: Public Assistance Status
type: NamedIndividual
type: NodeShape
comment: A class that indicates a person or household does not receive a form of public assistance

Does Not Receive Food Assistance
type: Class
subclass of: Does Not Receive Public Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A class that indicates a person or household does not receive food assistance
notation: HHEAR_709

Does Not Receive Housing Assistance
type: Class
subclass of: Does Not Receive Public Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A class that indicates a person or household does not receive housing assistance
notation: HHEAR_710

Does Not Receive Income Assistance
type: Class
subclass of: Does Not Receive Public Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A class that indicates a person or household does not income housing assistance
notation: HHEAR_711

Does Not Receive Utility Assistance
type: Class
subclass of: Does Not Receive Public Assistance
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A class that indicates a person or household does not utility housing assistance
notation: HHEAR_712

Ages and Stages Communication Questionnaire
type: Class
subclass of: Ages and Stages Questionnaire
type: NamedIndividual
type: NodeShape
comment: The "communication" section of the Ages and Stages Questionnaire

Population Group by Recruitment Location
type: Class
subclass of: Population Group
type: NamedIndividual
type: NodeShape
comment: This class denotes Population Group by Recruitment Location

San Diego, CA Site
type: Class
subclass of: Population Group by Study Site
subclass of: Restriction
  on property: SIO_000668
  has value: Q16552
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes San Diego, CA Site
notation: HHEAR_718

Boston, MA Site
type: Class
subclass of: Population Group by Study Site
subclass of: Restriction
  on property: SIO_000668
  has value: Q100
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Boston, MA Site
notation: HHEAR_717

St. Louis, MO Site
type: Class
subclass of: Population Group by Study Site
subclass of: Restriction
  on property: SIO_000668
  has value: Q38022
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes St. Louis, MO Site
notation: HHEAR_719

Liver Biopsy
type: Class
subclass of: Biospecimen Collection
type: NamedIndividual
type: NodeShape
comment: The collection of sample tissue from a subject's liver

Serum Collection
type: Class
subclass of: Biospecimen Collection
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A time interval during which serum blood is collected from a subject
notation: HHEAR_925

Serum Collection During Childhood
type: Class
equivalent class: Class
  intersection of: Serum Collection
  intersection of: Restriction
    on property: intervalDuring
    some values from: Childhood Period
subclass of: Serum Collection
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
type: NamedIndividual
type: NodeShape
comment: A time interval during which serum blood is collected from a subject that occurs during the subject's childhood period

Liver Biopsy During Childhood
type: Class
equivalent class: Class
  intersection of: Liver Biopsy
  intersection of: Restriction
    on property: intervalDuring
    some values from: Childhood Period
subclass of: Liver Biopsy
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
type: NamedIndividual
type: NodeShape
comment: The collection of tissue from a subject's liver that occurs during the subject's childhood period

Grade of Steatosis in Liver
type: Class
equivalent class: Class
  intersection of: Measurement
  intersection of: Restriction
    on property: SIO_000215
    some values from: Hepatic Steatosis
equivalent class: Class
  intersection of: Measurement
  intersection of: Restriction
    on property: SIO_000215
    some values from: Hepatocellular Ballooning Assessment
subclass of: Measurement
subclass of: Restriction
  on property: SIO_000215
  some values from: Hepatic Steatosis
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A measurement of the severity of steatosis in the liver

Hepatocellular Ballooning Measurement
type: Class
equivalent class: Class
  intersection of: Measurement
  intersection of: Restriction
    on property: SIO_000215
    some values from: Hepatocellular Ballooning Assessment
subclass of: Measurement
subclass of: Restriction
  on property: SIO_000215
  some values from: Hepatocellular Ballooning Assessment
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A measurement from a hepatocellular ballooning assessment

Few Ballooning Hepatocytes Measurement
type: Class
subclass of: Hepatocellular Ballooning Measurement
disjoint with: Many Ballooning Hepatocytes Measurement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes a measurement of few ballooning hepatocytes
notation: HHEAR_743

Many Ballooning Hepatocytes Measurement
type: Class
subclass of: Hepatocellular Ballooning Measurement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes a measurement of many ballooning hepatocytes
notation: HHEAR_744

Portal Inflammation Measurement
type: Class
equivalent class: Class
  intersection of: Measurement
  intersection of: Restriction
    on property: SIO_000215
    some values from: Portal Inflammation Assessment
subclass of: Measurement
subclass of: Restriction
  on property: SIO_000215
  some values from: Portal Inflammation Assessment
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A measurement from a Portal Inflammation Assessment

Mild Hepatic Portal Inflammation
type: Class
subclass of: Portal Inflammation Measurement
disjoint with: More Than Mild Hepatic Portal Inflammation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Mild Hepatic Portal Inflammation
notation: HHEAR_745

More Than Mild Hepatic Portal Inflammation
type: Class
subclass of: Portal Inflammation Measurement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes More Than Mild Hepatic Portal Inflammation
notation: HHEAR_746

Zone 3: Suspicious, Borderline, or Indeterminate Periportal Pattern
type: Class
subclass of: Pathology Result
subclass of: Restriction
  on property: SIO_000668
  some values from: non-alcoholic fatty liver disease
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Zone 3: Suspicious, Borderline, or Indeterminate Periportal Pattern
notation: HHEAR_753

Zone 1: Suspicious, Borderline, or Indeterminate Periportal Pattern
type: Class
subclass of: Pathology Result
subclass of: Restriction
  on property: SIO_000668
  some values from: non-alcoholic fatty liver disease
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Zone 1: Suspicious, Borderline, or Indeterminate Periportal Pattern
notation: HHEAR_749

Zone 3: Mild Perisinusoidal
type: Class
subclass of: Pathology Result
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Zone 3: Mild Perisinusoidal
notation: HHEAR_751

Zone 3: Moderate Perisinusoidal
type: Class
subclass of: Pathology Result
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Zone 3: Moderate Perisinusoidal
notation: HHEAR_752

Zone 3 and Periportal: Any Combination
type: Class
subclass of: Pathology Result
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Zone 3 and Periportal: Any Combination
notation: HHEAR_750

microunits per liter
type: Class
subclass of: unit per volume unit
type: NamedIndividual
type: NodeShape
comment: This class denotes microunits per liter

Uses Albuterol Inhaler
type: Class
subclass of: Albuterol Inhaler Use
subclass of: Restriction
  on property: SIO_000139
  some values from: albuterol
disjoint with: Does Not Use Albuterol Inhaler
type: NamedIndividual
type: Quality Value
comment: Indicates that a subject uses an Albuterol inhaler to control acute asthma symptoms.
notation: HHEAR_723

Uses Corticosteroid Inhaler
type: Class
subclass of: Corticosteroid Inhaler Use
subclass of: Restriction
  on property: SIO_000139
  some values from: corticosteroid
disjoint with: Does Not Use Corticosteroid Inhaler
type: NamedIndividual
type: Quality Value
comment: Indicates that a subject uses a corticosteroid inhaler to control asthma symptoms.
notation: HHEAR_725

Uses Other Asthma Medication
type: Class
subclass of: Other Asthma Medication Use
disjoint with: Does Not Use Other Asthma Medication
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Uses some other asthma medication besides Albuterol or an inhaled corticosteroid (ex. Cromolyn and Nedocromil, Oral Leukotriene Modifiers, Oral Theophylline, Oral Corticosteroids).
notation: HHEAR_724

Completed Eighth Grade But Not A High School Graduate
type: Class
subclass of: Some Middle School
disjoint with: Less Than Grade 8
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Completed Eighth Grade But Not A High School Graduate
notation: HHEAR_726

Annual Income $30,000 to $34,999
type: Class
subclass of: Annual Income $25,000 to $34,999
subclass of: Annual Income $30,000 to $39,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 34999
subclass of: Restriction
  on property: minValue
  has value: 30000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $30,000 to $34,999
notation: HHEAR_727

Annual Income $35,000 to $39,999
type: Class
subclass of: Annual Income $35,000 to $44,999
subclass of: Annual Income $30,000 to $39,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 39999
subclass of: Restriction
  on property: minValue
  has value: 35000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $35,000 to $39,999
notation: HHEAR_728

Annual Income $40,000 to $44,999
type: Class
subclass of: Annual Income $35,000 to $44,999
subclass of: Annual Income $40,000 to $49,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 44999
subclass of: Restriction
  on property: minValue
  has value: 40000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $40,000 to $44,999
notation: HHEAR_729

Annual Income $45,000 to $49,999
type: Class
subclass of: Annual Income $45,000 to $54,999
subclass of: Annual Income $40,000 to $49,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 49999
subclass of: Restriction
  on property: minValue
  has value: 45000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $45,000 to $49,999
notation: HHEAR_730

Annual Income More Than $50,000
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: minValue
  has value: 50000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income More Than $50,000
notation: HHEAR_731

Number of Puffs of Albuterol
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Puff of Albuterol
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Puffs of Albuterol

Puff of Albuterol
type: Class
subclass of: Uses Albuterol Inhaler
subclass of: SIO_001019
subclass of: Restriction
  on property: SIO_000230
  some values from: albuterol
type: NamedIndividual
type: NodeShape
comment: A single administration of inhaled Albuterol

Number of Puffs of Albuterol Since Going to Sleep
type: Class
subclass of: Number of Puffs of Albuterol
subclass of: Number of Nights of Albuterol Use
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Puffs of Albuterol Since Going to Sleep

Number of Puffs of Albuterol Since Peak Flow in AM
type: Class
subclass of: Number of Puffs of Albuterol
subclass of: Number of Nights of Albuterol Use
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Puffs of Albuterol Since Peak Flow in AM

Study Activity
type: Class
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: An event or activity that occurs as part of a scientific study. Such events may include interviewing subjects, administering tests to subjects, or collecting biological samples or environmental samples.

Study Followup Day 1
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The first day of a study followup activity

Childhood Followup Day 1
type: Class
subclass of: Study Followup Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The first day of a study followup activity that occurs during a subject's childhood period

Study Followup Day 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The second day of a study followup activity

Childhood Followup Day 2
type: Class
subclass of: Study Followup Day 2
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The second day of a study followup activity that occurs during a subject's childhood period

Study Followup Day 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The third day of a study followup activity

Childhood Followup Day 3
type: Class
subclass of: Study Followup Day 3
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The third day of a study followup activity that occurs during a subject's childhood period

Study Followup Day 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The fourth day of a study followup activity

Childhood Followup Day 4
type: Class
subclass of: Study Followup Day 4
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The fourth day of a study followup activity that occurs during a subject's childhood period

Study Followup 2 Day 1
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The first day of the second study followup activity for a study

Childhood Followup 2 Day 1
type: Class
subclass of: Study Followup 2 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The first day of the second study followup activity for a study that occurs during a subject's childhood period

Study Followup 2 Day 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The second day of the second study followup activity for a study

Childhood Followup 2 Day 2
type: Class
subclass of: Study Followup 2 Day 2
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The second day of the second study followup activity for a study that occurs during a subject's childhood period

Study Followup 2 Day 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The third day of the second study followup activity for a study

Childhood Followup 2 Day 3
type: Class
subclass of: Study Followup 2 Day 3
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The third day of the second study followup activity for a study that occurs during a subject's childhood period

Study Followup 2 Day 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The fourth day of the second study followup activity for a study

Childhood Followup 2 Day 4
type: Class
subclass of: Study Followup 2 Day 4
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The fourth day of the second study followup activity for a study that occurs during a subject's childhood period

Study Followup 3 Day 1
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The first day of the third study followup activity for a study

Childhood Followup 3 Day 1
type: Class
subclass of: Study Followup 3 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The first day of the third study followup activity for a study that occurs during a subject's childhood period

Study Followup 3 Day 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The second day of the third study followup activity for a study

Childhood Followup 3 Day 2
type: Class
subclass of: Study Followup 3 Day 2
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The second day of the third study followup activity for a study that occurs during a subject's childhood period

Study Followup 3 Day 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The third day of the third study followup activity for a study

Childhood Followup 3 Day 3
type: Class
subclass of: Study Followup 3 Day 3
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The third day of the third study followup activity for a study that occurs during a subject's childhood period

Study Followup 3 Day 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The fourth day of the third study followup activity for a study

Childhood Followup 3 Day 4
type: Class
subclass of: Study Followup 3 Day 4
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The fourth day of the third study followup activity for a study that occurs during a subject's childhood period

Study Followup 4 Day 1
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The first day of the fourth study followup activity for a study

Childhood Followup 4 Day 1
type: Class
subclass of: Study Followup 4 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The first day of the fourth study followup activity for a study that occurs during a subject's childhood period

Study Followup 4 Day 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The second day of the fourth study followup activity for a study

Childhood Followup 4 Day 2
type: Class
subclass of: Study Followup 4 Day 2
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The second day of the fourth study followup activity for a study that occurs during a subject's childhood period

Study Followup 4 Day 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The third day of the fourth study followup activity for a study

Childhood Followup 4 Day 3
type: Class
subclass of: Study Followup 4 Day 3
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The third day of the fourth study followup activity for a study that occurs during a subject's childhood period

Study Followup 4 Day 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The fourth day of the fourth study followup activity for a study

Childhood Followup 4 Day 4
type: Class
subclass of: Study Followup 4 Day 4
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The fourth day of the fourth study followup activity for a study that occurs during a subject's childhood period

Albuterol Inhaler Use
type: Class
subclass of: Asthma Controller Use
type: NamedIndividual
type: NodeShape
comment: Indicates whether or not a subject uses or does not use an Albuterol inhaler for asthma

Corticosteroid Inhaler Use
type: Class
subclass of: Asthma Controller Use
type: NamedIndividual
type: NodeShape
comment: Indicates whether or not a subject uses or does not use a corticosteroid inhaler for asthma

Other Asthma Medication Use
type: Class
subclass of: Asthma Controller Use
type: NamedIndividual
type: NodeShape
comment: Indicates whether or not a subject uses or does not use asthma control medication other than an Albuterol or corticosteroid inhaler (ex. Cromolyn and Nedocromil, Oral Leukotriene Modifiers, Oral Theophylline, Oral Corticosteroids).

Does Not Use Albuterol Inhaler
type: Class
subclass of: Albuterol Inhaler Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject does not use an Albuterol inhaler to control acute asthma symptoms.
notation: HHEAR_732

Does Not Use Corticosteroid Inhaler
type: Class
subclass of: Corticosteroid Inhaler Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject does not use a corticosteroid inhaler to control asthma symptoms.
notation: HHEAR_733

Does Not Use Other Asthma Medication
type: Class
subclass of: Other Asthma Medication Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Does not use some other asthma medication besides Albuterol or an inhaled corticosteroid (ex. Cromolyn and Nedocromil, Oral Leukotriene Modifiers, Oral Theophylline, Oral Corticosteroids).
notation: HHEAR_734

FEV1 Best Value (pre-bronchodilator administration)
type: Class
subclass of: FEV1 Best Value
subclass of: Forced Expiratory Volume (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: Measured FEV1 best value prior to administration of bronchodilator

FEV1 Best Value (post-bronchodilator administration)
type: Class
subclass of: FEV1 Best Value
subclass of: Forced Expiratory Volume (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: Measured FEV1 best value after administration of bronchodilator

FEV1 Percent Predicted Value (pre-bronchodilator administration)
type: Class
subclass of: FEV1 Percent Predicted Value
subclass of: Forced Expiratory Volume (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The percent ratio of a patient's best FEV1 value divided by the expected or predicted FEV1 value prior to administering bronchodilator

FEV1 Percent Predicted Value (post-bronchodilator administration)
type: Class
subclass of: FEV1 Percent Predicted Value
subclass of: Forced Expiratory Volume (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The percent ratio of a patient's best FEV1 value divided by the expected or predicted FEV1 value after administering bronchodilator

FEV1 Predicted Value (pre-bronchodilator administration)
type: Class
subclass of: FEV1 Predicted Value
subclass of: Forced Expiratory Volume (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The expected or predicted FEV1 value prior to administering bronchodilator

FEV1 Predicted Value (post-bronchodilator administration)
type: Class
subclass of: FEV1 Predicted Value
subclass of: Forced Expiratory Volume (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The expected or predicted FEV1 value after administering bronchodilator

FVC Predicted Value (pre-bronchodilator administration)
type: Class
subclass of: FVC Predicted Value
subclass of: Forced Vital Capacity (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The expected or predicted FVC value prior to administering bronchodilator

FVC Predicted Value (post-bronchodilator administration)
type: Class
subclass of: FVC Predicted Value
subclass of: Forced Vital Capacity (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The expected or predicted FVC value after administering bronchodilator

FVC Best Value (pre-bronchodilator administration)
type: Class
subclass of: FVC Best Value
subclass of: Forced Vital Capacity (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: Measured FVC best value prior to administration of bronchodilator

FVC Best Value (post-bronchodilator administration)
type: Class
subclass of: FVC Best Value
subclass of: Forced Vital Capacity (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: Measured FVC best value after administration of bronchodilator

FVC Percent Predicted Value (pre-bronchodilator administration)
type: Class
subclass of: FVC Percent Predicted Value
subclass of: Forced Vital Capacity (pre-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The percent ratio of a patient's best FVC value divided by the expected or predicted FEV1 value prior to administering bronchodilator

FVC Percent Predicted Value (post-bronchodilator administration)
type: Class
subclass of: FVC Percent Predicted Value
subclass of: Forced Vital Capacity (post-bronchodilator administration)
type: NamedIndividual
type: NodeShape
comment: The percent ratio of a patient's best FVC value divided by the expected or predicted FEV1 value after administering bronchodilator

Millions Per Cubic Millimeter
type: Class
subclass of: cell concentration unit
type: NamedIndividual
type: NodeShape
comment: A unit of concentration typically used for expressing the count of millions of cells appearing within one cubic millimeter volume of plasma

Thousands Per Cubic Millimeter
type: Class
subclass of: cell concentration unit
type: NamedIndividual
type: NodeShape
comment: A unit of concentration typically used for expressing the count of thousands of cells appearing within a one cubic millimeter volume of plasma

Unit Per Cubic Millimeter
type: Class
subclass of: cell concentration unit
type: NamedIndividual
type: NodeShape
comment: A unit of concentration typically used for expressing the count of cells appearing within a one millimeter cubed volume of plasma

mononuclear cell percentage
type: Class
subclass of: mononuclear cell measurement
subclass of: SIO_001413
type: NamedIndividual
type: NodeShape
comment: This class denotes mononuclear cell percentage

Immature Granulocytes Measurement
type: Class
subclass of: cell measurement
type: NamedIndividual
type: NodeShape
comment: This class denotes Immature Granulocytes Measurement

Immature Granulocytes Per Unit Volume Measurement
type: Class
subclass of: Immature Granulocytes Measurement
type: NamedIndividual
type: NodeShape
comment: The determination of the number of immature granulocytes per unit volume present in a sample.

Number of Members of Household Except Subject
type: Class
subclass of: Number of Members in Household
type: NamedIndividual
type: NodeShape
comment: The number of people residing in a household, except for the subject of the study

Number of Members of Household Except Parents
type: Class
subclass of: Number of Members in Household
type: NamedIndividual
type: NodeShape
comment: The number of people residing in a household, except for the parents of the study subject

Annual Income $25,000 to $50,000
type: Class
subclass of: Annual Income $20,000 to $50,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 50000
subclass of: Restriction
  on property: minValue
  has value: 25000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $25,000 to $50,000
notation: HHEAR_939

Less than 5% Hepatic Steatosis
type: Class
subclass of: Grade of Steatosis in Liver
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Less than 5% Hepatic Steatosis
notation: HHEAR_735

Between 5% and 33% Hepatic Steatosis
type: Class
subclass of: Grade of Steatosis in Liver
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Between 5% and 33% Hepatic Steatosis
notation: HHEAR_737

Between 34% and 66% Hepatic Steatosis
type: Class
subclass of: Grade of Steatosis in Liver
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Between 34% and 66% Hepatic Steatosis
notation: HHEAR_738

Greater than 66% Hepatic Steatosis
type: Class
subclass of: Grade of Steatosis in Liver
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Greater than 66% Hepatic Steatosis
notation: HHEAR_736

Level of Hepatic Lobular Inflammation
type: Class
subclass of: Measurement
subclass of: Restriction
  on property: SIO_000215
  some values from: Hepatic Lobular Inflammation
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: A measurement of the level or degree of lobular inflammation in the liver

Less than 2 Foci Under 20x Magnification
type: Class
subclass of: Level of Hepatic Lobular Inflammation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Less than 2 Foci Under 20x Magnification
notation: HHEAR_740

Between 2 and 4 Foci Under 20x Magnification
type: Class
subclass of: Level of Hepatic Lobular Inflammation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Between 2 and 4 Foci Under 20x Magnification
notation: HHEAR_742

Greater than 4 Foci Under 20x Magnification
type: Class
subclass of: Level of Hepatic Lobular Inflammation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Greater than 4 Foci Under 20x Magnification
notation: HHEAR_741

No Foci Present Under 20x Magnification
type: Class
subclass of: Level of Hepatic Lobular Inflammation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes No Foci Present Under 20x Magnification
notation: HHEAR_739

Discover Questionnaire Response
type: Class
subclass of: Physical And Mental Assessment
subclass of: Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Discover Questionnaire Response

Asthma Induced Sleeplessness Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced Sleeplessness Response

Not Woken Up By Asthma Overnight
type: Class
subclass of: Asthma Induced Sleeplessness Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Not Woken Up By Asthma Overnight
notation: HHEAR_758

Woken Up By Asthma Once Overnight
type: Class
subclass of: Asthma Induced Sleeplessness Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Woken Up By Asthma Once Overnight
notation: HHEAR_759

Woken Up By Asthma More Than Once Overnight
type: Class
subclass of: Asthma Induced Sleeplessness Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Woken Up By Asthma More Than Once Overnight
notation: HHEAR_760

Kept Awake By Asthma All Night
type: Class
subclass of: Asthma Induced Sleeplessness Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Kept Awake By Asthma All Night
notation: HHEAR_761

Asthma Induced School Absenteeism Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced School Absenteeism Response

Absent Part of the Day Due to Asthma
type: Class
subclass of: Asthma Induced School Absenteeism Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Absent Part of the Day Due to Asthma

Not Absent Due to Asthma
type: Class
subclass of: Asthma Induced School Absenteeism Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Not Absent Due to Asthma
notation: HHEAR_764

Absent Due to Asthma
type: Class
subclass of: Asthma Induced School Absenteeism Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Absent Due to Asthma
notation: HHEAR_762

Not Absent Due to Weekend or Vacation
type: Class
subclass of: Asthma Induced School Absenteeism Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Not Absent Due to Weekend or Vacation
notation: HHEAR_765

Asthma Induced Medical Encounter Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced Medical Encounter Response

Visited Doctor, ER, or Hospital Due to Asthma
type: Class
subclass of: Asthma Induced Medical Encounter Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Visited Doctor, ER, or Hospital Due to Asthma
notation: HHEAR_938

Did Not Visit Doctor, ER, or Hospital Due to Asthma
type: Class
subclass of: Asthma Induced Medical Encounter Response
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Did Not Visit Doctor, ER, or Hospital Due to Asthma
notation: HHEAR_937

Asthma Induced Trouble Breathing Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced Trouble Breathing Response

Never Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Never Had Trouble Breathing Today
notation: HHEAR_770

A Little of the Time Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes A Little of the Time Had Trouble Breathing Today
notation: HHEAR_767

A Good Bit of the Time Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes A Good Bit of the Time Had Trouble Breathing Today
notation: HHEAR_766

Some of the Time Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some of the Time Had Trouble Breathing Today
notation: HHEAR_771

Most of the Time Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Most of the Time Had Trouble Breathing Today
notation: HHEAR_769

All of the Time Had Trouble Breathing Today
type: Class
subclass of: Asthma Induced Trouble Breathing Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes All of the Time Had Trouble Breathing Today
notation: HHEAR_768

Asthma Induced Distress Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced Distress Response

Did Not Bother Me Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Did Not Bother Me Today
notation: HHEAR_772

Bothered Me A Little Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bothered Me A Little Today
notation: HHEAR_776

Bothered Me Somewhat Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bothered Me Somewhat Today
notation: HHEAR_774

Bothered Me A Good Deal Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bothered Me A Good Deal Today
notation: HHEAR_777

Bothered Me Very Much Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bothered Me Very Much Today
notation: HHEAR_773

Bothered Me As Much As Possible Today
type: Class
subclass of: Asthma Induced Distress Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bothered Me As Much As Possible Today
notation: HHEAR_775

Asthma Induced Activity Limitation Response
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Induced Activity Limitation Response

Asthma Did Not Limit Activity
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001289
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Did Not Limit Activity
notation: HHEAR_778

Asthma Limited Activity A Little of the Time
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Limited Activity A Little of the Time
notation: HHEAR_780

Asthma Limited Activity Some of the Time
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001290
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Limited Activity Some of the Time
notation: HHEAR_783

Asthma Limited Activity A Good Bit of the Time
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Limited Activity A Good Bit of the Time
notation: HHEAR_779

Asthma Limited Activity Most of the Time
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001291
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Limited Activity Most of the Time
notation: HHEAR_782

Asthma Limited Activity All of the Time
type: Class
subclass of: Asthma Induced Activity Limitation Response
subclass of: SIO_001292
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Asthma Limited Activity All of the Time
notation: HHEAR_781

Terrace House End
type: Class
subclass of: Q875016
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A unit in a terrace or row house that is on the end. I.e. one that shares only one side with another unit.
alternative label: Row House End
notation: HHEAR_787

Residential Building With Central Air Conditioning
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000369
    some values from: Q91660517
subclass of: Residential Building
subclass of: Restriction
  on property: SIO_000369
  some values from: Q91660517
disjoint with: Residential Building Without Central Air Conditioning
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Residential Building With Central Air Conditioning
notation: HHEAR_788

Residential Building Without Central Air Conditioning
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Class
    complement of: Residential Building With Central Air Conditioning
subclass of: Residential Building
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Residential Building Without Central Air Conditioning
notation: HHEAR_789

Human Dwelling by Physical Condition
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling by Physical Condition

Extremely Poor Condition Human Dwelling
type: Class
subclass of: Human Dwelling by Physical Condition
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Extremely Poor Condition Human Dwelling
notation: HHEAR_794

Below Average Condition Human Dwelling
type: Class
subclass of: Human Dwelling by Physical Condition
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Below Average Condition Human Dwelling
notation: HHEAR_792

Average Condition Human Dwelling
type: Class
subclass of: Human Dwelling by Physical Condition
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Average Condition Human Dwelling
notation: HHEAR_791

Above Average Condition Human Dwelling
type: Class
subclass of: Human Dwelling by Physical Condition
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Above Average Condition Human Dwelling
notation: HHEAR_790

Excellent Condition Human Dwelling
type: Class
subclass of: Human Dwelling by Physical Condition
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Excellent Condition Human Dwelling
notation: HHEAR_793

Human Dwelling By Evidence of Moisture Damage
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling By Evidence of Moisture Damage

Human Dwelling With No Evidence of Moisture Damage
type: Class
subclass of: Human Dwelling By Evidence of Moisture Damage
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With No Evidence of Moisture Damage
notation: HHEAR_795

Human Dwelling With Some Evidence of Moisture Damage
type: Class
subclass of: Human Dwelling By Evidence of Moisture Damage
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Some Evidence of Moisture Damage
notation: HHEAR_796

Human Dwelling With Much Evidence of Moisture Damage
type: Class
subclass of: Human Dwelling By Evidence of Moisture Damage
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Much Evidence of Moisture Damage
notation: HHEAR_797

Rug
type: Class
subclass of: Q163446
type: NamedIndividual
type: NodeShape
comment: A rug or carpet that is not wall-to-wall

Hardwood Flooring
type: Class
subclass of: Q47011175
type: NamedIndividual
type: NodeShape
comment: This class denotes Hardwood Flooring

Large Rug
type: Class
subclass of: Rug
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A large rug
notation: HHEAR_940

Scatter Rug
type: Class
subclass of: Rug
type: NamedIndividual
type: NodeShape
comment: A scatter rug

Human Dwelling By Floor Covering Type
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Human Dwelling By Floor Covering Type

Human Dwelling With Wall to Wall Carpet
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q1753602
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes a human dwelling with wall-to-wall carpet.
notation: HHEAR_876

Facet Category
type: Class
subclass of: Class
type: NamedIndividual
type: NodeShape
comment: A class used as the top-level category for a search facet

Facet
type: Class
subclass of: Class
type: NamedIndividual
type: NodeShape
comment: A class used as a search facet

Facet Value
type: Class
subclass of: Class
type: NamedIndividual
type: NodeShape
comment: A class used as a value for a search facet

Age From 00 to 01 Years Old
type: Class
subclass of: SIO_001013
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at birth and ending at the end of the subject's first year.
notation: HHEAR_1046

Age From 02 to 12 Years Old
type: Class
subclass of: SIO_001013
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their second year and ending at the end of their twelfth year.
notation: HHEAR_1047

Age From 13 to 17 Years Old
type: Class
subclass of: SIO_001013
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their thirteenth year and ending at the end of their seventeenth year.
notation: HHEAR_1048

Age of 18 Years or Older
type: Class
subclass of: SIO_001013
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their eighteenth year.

Study Population
type: Class
subclass of: Study Indicator
type: NamedIndividual
type: Facet Category
type: NodeShape
comment: This class denotes Study Population

Pregnancy Month 2
type: Class
subclass of: SIO_000417
definition: The second month of pregnancy

Pregnancy Month 3
type: Class
subclass of: SIO_000417
definition: The third month of pregnancy

Pregnancy Month 4
type: Class
subclass of: SIO_000417
definition: The fourth month of pregnancy

Pregnancy Month 5
type: Class
subclass of: SIO_000417
definition: The fifth month of pregnancy

Pregnancy Month 7
type: Class
subclass of: SIO_000417
definition: The seventh month of pregnancy

Pregnancy Month 8
type: Class
subclass of: SIO_000417
definition: The eighth month of pregnancy

Pregnancy Month 9
type: Class
subclass of: SIO_000417
definition: The ninth month of pregnancy

Study Baseline Day 1
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The first day of the baseline activity for a study

Study Baseline Day 2
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The second day of the baseline activity for a study

Study Baseline Day 3
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The third day of the baseline activity for a study

Study Baseline Day 4
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The fourth day of the baseline activity for a study

Study Baseline Day 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The fifth day of the baseline activity for a study

Study Baseline Day 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The sixth day of the baseline activity for a study

Study Baseline Day 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The seventh day of the baseline activity for a study

Study Baseline Day 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: The eighth day of the baseline activity for a study

Childhood Baseline Day 1
type: Class
subclass of: Study Baseline Day 1
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The first day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 2
type: Class
subclass of: Study Baseline Day 2
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The second day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 3
type: Class
subclass of: Study Baseline Day 3
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The third day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 4
type: Class
subclass of: Study Baseline Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The fourth day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 5
type: Class
subclass of: Study Baseline Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The fifth day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 6
type: Class
subclass of: Study Baseline Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The sixth day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 7
type: Class
subclass of: Study Baseline Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The seventh day of the baseline activity for a study that occurs during a subject's childhood period

Childhood Baseline Day 8
type: Class
subclass of: Study Baseline Day 8
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: The eighth day of the baseline activity for a study that occurs during a subject's childhood period

Study Followup Day 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The fifth day of a study followup activity

Study Followup Day 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The sixth day of a study followup activity

Study Followup Day 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The seventh day of a study followup activity

Study Followup Day 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: The eighth day of a study followup activity

Childhood Followup Day 5
type: Class
subclass of: Study Followup Day 5
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The fifth day of a study followup activity that occurs during a subject's childhood period

Childhood Followup Day 6
type: Class
subclass of: Study Followup Day 6
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The sixth day of a study followup activity that occurs during a subject's childhood period

Childhood Followup Day 7
type: Class
subclass of: Study Followup Day 7
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The seventh day of a study followup activity that occurs during a subject's childhood period

Childhood Followup Day 8
type: Class
subclass of: Study Followup Day 8
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: The eighth day of a study followup activity that occurs during a subject's childhood period

Study Followup 2 Day 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The fifth day of the second study followup activity for a study

Study Followup 2 Day 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The sixth day of the second study followup activity for a study

Study Followup 2 Day 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The seventh day of the second study followup activity for a study

Study Followup 2 Day 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 2 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: The eighth day of the second study followup activity for a study

Childhood Followup 2 Day 5
type: Class
subclass of: Study Followup 2 Day 5
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The fifth day of the second study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 2 Day 6
type: Class
subclass of: Study Followup 2 Day 6
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The sixth day of the second study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 2 Day 7
type: Class
subclass of: Study Followup 2 Day 7
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The seventh day of the second study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 2 Day 8
type: Class
subclass of: Study Followup 2 Day 8
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 2 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: The eighth day of the second study followup activity for a study that occurs during a subject's childhood period

Study Followup 3 Day 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The fifth day of the third study followup activity for a study

Study Followup 3 Day 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The sixth day of the third study followup activity for a study

Study Followup 3 Day 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The seventh day of the third study followup activity for a study

Study Followup 3 Day 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 3 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: The eighth day of the third study followup activity for a study

Childhood Followup 3 Day 5
type: Class
subclass of: Study Followup 3 Day 5
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The fifth day of the third study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 3 Day 6
type: Class
subclass of: Study Followup 3 Day 6
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The sixth day of the third study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 3 Day 7
type: Class
subclass of: Study Followup 3 Day 7
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The seventh day of the third study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 3 Day 8
type: Class
subclass of: Study Followup 3 Day 8
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 3 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 3
type: NamedIndividual
type: NodeShape
comment: The eighth day of the third study followup activity for a study that occurs during a subject's childhood period

Study Followup 4 Day 5
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The fifth day of the fourth study followup activity for a study

Study Followup 4 Day 6
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The sixth day of the fourth study followup activity for a study

Study Followup 4 Day 7
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The seventh day of the fourth study followup activity for a study

Study Followup 4 Day 8
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: intervalAfter
  some values from: Study Followup 4 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: The eighth day of the fourth study followup activity for a study

Childhood Followup 4 Day 5
type: Class
subclass of: Study Followup 4 Day 5
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 4
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The fifth day of the fourth study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 4 Day 6
type: Class
subclass of: Study Followup 4 Day 6
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 5
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The sixth day of the fourth study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 4 Day 7
type: Class
subclass of: Study Followup 4 Day 7
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 6
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The seventh day of the fourth study followup activity for a study that occurs during a subject's childhood period

Childhood Followup 4 Day 8
type: Class
subclass of: Study Followup 4 Day 8
subclass of: Restriction
  on property: intervalAfter
  some values from: Childhood Followup 4 Day 7
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Followup 4
type: NamedIndividual
type: NodeShape
comment: The eighth day of the fourth study followup activity for a study that occurs during a subject's childhood period

Funding Institute
type: Class
subclass of: SIO_000688
type: NamedIndividual
type: Facet Category
type: NodeShape
comment: This class denotes Funding Institute

Other Funding Institute
type: Class
subclass of: Funding Institute
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Other Funding Institute

Biomarker Validation
type: Class
subclass of: Validation
subclass of: Health Outcome
subclass of: Restriction
  on property: SIO_000668
  some values from: biomarker
type: NamedIndividual
type: Facet
type: NodeShape
comment: This class denotes Biomarker Validation

Systolic blood pressure Z-Score
type: Class
subclass of: systolic blood pressure
subclass of: Z-Score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
definition: Z-Score of the systolic blood pressure.
editorial note: from 'AAP Clinical Practice Guidelines, 5th Report': as of 2017

Diastolic blood pressure Z-Score
type: Class
subclass of: diastolic blood pressure
subclass of: Z-Score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
definition: Z-Score of the diastolic blood pressure.
editorial note: from 'AAP Clinical Practice Guidelines, 5th Report': as of 2017

Average daily total fat intake
type: Class
subclass of: ONS_0000025
subclass of: UO_0000003
subclass of: Diet and Nutrition
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Average daily total fat intake

Average Daily Total Saturated Fatty Acid Intake
type: Class
subclass of: ONS_0000026
subclass of: UO_0000003
subclass of: Diet and Nutrition
subclass of: SIO_001109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Average Daily Total Saturated Fatty Acid Intake

Arterial Stiffness Measured By Pulse Wave Velocity Above 6.767
type: Class
subclass of: EFO_0004517
subclass of: EFO_0004724
subclass of: Class
  intersection of: EFO_0004724
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
comment: This class denotes Arterial Stiffness Measured By Pulse Wave Velocity Above 6.767
notation: HHEAR_799
scope note: PWV (Pulse Wave Velocity) Definition: a measure of arterial stiffness; term exists in efo ontology has a term: efo:0004724. This term is study specific. In the data dictionary, label for the variable also includes information: cutpoint based on 90th percentile of 202 controls that are age 10 or older; as well as if pwvf_e < 6.767 then art_stiff = 0; if pwvf_e ≥ 6.767 then art_stiff = 1

Arterial Stiffness Measured By Pulse Wave Velocity Below 6.767
type: Class
subclass of: EFO_0004517
subclass of: EFO_0004724
subclass of: Class
  intersection of: EFO_0004724
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
comment: This class denotes Arterial Stiffness Measured By Pulse Wave Velocity Below 6.767
editorial note: change the label to be more informative of the intention
notation: HHEAR_798
scope note: PWV (Pulse Wave Velocity) Definition: a measure of arterial stiffness; term exists in efo ontology has a term: efo:0004724. This term is study specific. In the data dictionary, label for the variable also includes information: cutpoint based on 90th percentile of 202 controls that are age 10 or older; as well as if pwvf_e < 6.767 then art_stiff = 0; if pwvf_e ≥ 6.767 then art_stiff = 1

Some College Up To And Including Associates Degree
type: Class
subclass of: Some College
subclass of: Demographic
subclass of: Socioeconomic Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some College Up To And Including Associates Degree
notation: HHEAR_929

Bachelors Degree
type: Class
subclass of: College Graduate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Bachelors Degree
notation: HHEAR_800

Some College Bachelors Degree and more
type: Class
subclass of: Some College
subclass of: Demographic
subclass of: Socioeconomic Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some College Bachelors Degree and more
notation: HHEAR_801

SEARCH Population Group
type: Class
subclass of: Population Group
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes SEARCH Population Group
note: These subsequent categories are blinded study sites that will be nested under "Population Group" Model similar to way blinded groups were done in study 2018-2537

Site 1
type: Class
subclass of: SEARCH Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Jensen Blinded Population Group #1
notation: HHEAR_930

Site 2
type: Class
subclass of: SEARCH Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Jensen Blinded Population Group #2
notation: HHEAR_802

Site 3
type: Class
subclass of: SEARCH Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Jensen Blinded Population Group #3
notation: HHEAR_803

Site 4
type: Class
subclass of: SEARCH Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Jensen Blinded Population Group #4
notation: HHEAR_804

Site 5
type: Class
subclass of: SEARCH Population Group
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Jensen Blinded Population Group #5
notation: HHEAR_805

Fat Calorie Intake Daily Rate
type: Class
subclass of: food calorie intake rate
subclass of: food calorie intake measurement
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
subclass of: Class
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average daily total fat intake
type: NamedIndividual
type: Quantity Variable
comment: The mass percentage of daily uptake of calories that is contained in the average total daily fat intake.

Low Fat Diet With Daily Fat Calories <= 35% of Total
type: Class
equivalent class: Class
  intersection of: food calorie intake rate
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average daily total fat intake
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Value
comment: A category where the mass percentage of daily uptake of calories that is contained in the average total daily fat intake where the value is <= 35.0 percent.
notation: HHEAR_806

High Fat Diet With Daily Fat Calories > 35% Total
type: Class
equivalent class: Class
  intersection of: food calorie intake rate
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average daily total fat intake
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Value
comment: A category where the mass percentage of daily uptake of calories that is contained in the average total daily fat intake where the value is >35.0 percent.
notation: HHEAR_807

Saturated Fat Calorie Intake Daily Rate
type: Class
subclass of: food calorie intake rate
subclass of: food calorie intake measurement
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
subclass of: Class
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average Daily Total Saturated Fatty Acid Intake
comment: The mass percentage of daily uptake of calories that is contained in the average total daily fat intake.

Low Fat Diet With Daily Saturated Fat Calories <= 10% Total
type: Class
equivalent class: Class
  intersection of: food calorie intake rate
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average Daily Total Saturated Fatty Acid Intake
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Value
comment: A category where the mass percentage of daily uptake of calories that is contained in the average total daily saturated fat intake where the value is <= 10.0 percent.
notation: HHEAR_808

High Fat Diet With Daily Saturated Fat Calories > 10% Total
type: Class
equivalent class: Class
  intersection of: food calorie intake rate
  intersection of: mass percentage
  intersection of: Restriction
    on property: AFX_0001049
    some values from: Average Daily Total Saturated Fatty Acid Intake
  intersection of: Restriction
    on property: value
    some values from: Datatype
      on datatype: float
      with restrictions: nil
subclass of: Dietary Calories Measurement
subclass of: Diet and Nutrition
type: NamedIndividual
type: Quality Value
comment: A category where the mass percentage of daily uptake of calories that is contained in the average total daily saturated fat intake where the value is > 10.0 percent.
notation: HHEAR_809

Education Grade 5 or 6
type: Class
equivalent class: Class
  union of: Education Grade 5
  union of: Education Grade 6
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
subclass of: Class
  union of: Education Grade 5
  union of: Education Grade 6
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Education Grade 5 or 6
notation: HHEAR_810

Education Grade 7 or 8
type: Class
equivalent class: Class
  union of: Education Grade 7
  union of: Education Grade 8
subclass of: Education By Highest Grade Attained
subclass of: Some Middle School
subclass of: Class
  union of: Education Grade 7
  union of: Education Grade 8
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Education Grade 7 or 8
notation: HHEAR_811

Education Grade 10
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some High School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Education Grade 10
notation: HHEAR_812

Education Grade 11
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some High School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Education Grade 11
notation: HHEAR_813

Education Grade 12, No Diploma
type: Class
subclass of: Education By Highest Grade Attained
subclass of: Some High School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Education Grade 12, No Diploma
notation: HHEAR_814

Some College Less Than One Year
type: Class
subclass of: Some College
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some College Less Than One Year
notation: HHEAR_816

Some College More Than One Year, No Degree
type: Class
subclass of: Some College
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Some College More Than One Year, No Degree
notation: HHEAR_815

2-hydroxyfluorene + 3-hydroxyfluorene
type: Class
subclass of: polycyclic hydrocarbon
subclass of: Restriction
  on property: SIO_000369
  some values from: 2-hydroxyfluorene
subclass of: Restriction
  on property: SIO_000369
  some values from: 3-hydroxyfluorene
type: NamedIndividual
type: Facet Value
comment: This class denotes 2-hydroxyfluorene + 3-hydroxyfluorene
notation: FLUO2_FLUO3

Baseline Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: A time interval at which a sample is collected from a study participant that occurs during the baseline of a study

Followup Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Restriction
  on property: intervalDuring
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: A time interval at which a sample is collected from a study participant that occurs during the followup of a study

Household Income - Monthly - Suriname
type: Class
subclass of: Household Income
type: NamedIndividual
type: NodeShape
comment: The monthly household income in Suriname Dollar (SRD)

Monthly Income SRD 0 - 399
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 399
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: NodeShape
comment: 0 to 399 Suriname Dollars [SRD]
notation: HHEAR_818

Monthly Income SRD 400 - 799
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 799
subclass of: Restriction
  on property: minValue
  has value: 400
type: NamedIndividual
type: NodeShape
comment: 400 to 799 Suriname Dollars [SRD]
notation: HHEAR_819

Monthly Income SRD 800 - 1499
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 1499
subclass of: Restriction
  on property: minValue
  has value: 800
type: NamedIndividual
type: NodeShape
comment: 800 to 1499 Suriname Dollars [SRD]
notation: HHEAR_820

Monthly Income SRD 1500 - 2999
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 2999
subclass of: Restriction
  on property: minValue
  has value: 1500
type: NamedIndividual
type: NodeShape
comment: 1500 to 2999 Suriname Dollars [SRD]
notation: HHEAR_821

Monthly Income SRD 3000 - 4999
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 4999
subclass of: Restriction
  on property: minValue
  has value: 3000
type: NamedIndividual
type: NodeShape
comment: 3000 to 4999 Suriname Dollars [SRD]
notation: HHEAR_822

Monthly Income SRD 5000 - 9999
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 9999
subclass of: Restriction
  on property: minValue
  has value: 5000
type: NamedIndividual
type: NodeShape
comment: 5000 to 9999 Suriname Dollars [SRD]
notation: HHEAR_823

Monthly Income SRD 10000 - 14999
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: maxValue
  has value: 14999
subclass of: Restriction
  on property: minValue
  has value: 10000
type: NamedIndividual
type: NodeShape
comment: 10000 to 14999 Suriname Dollars [SRD]
notation: HHEAR_824

Monthly Income SRD 15000+
type: Class
subclass of: Household Income - Monthly - Suriname
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000429
subclass of: Restriction
  on property: currency
  has value: SRD
subclass of: Restriction
  on property: minValue
  has value: 15000
type: NamedIndividual
type: NodeShape
comment: 15000+ Suriname Dollars [SRD]
notation: HHEAR_825

Consenting Party
type: Class
subclass of: Legally Acceptable Representative
subclass of: Healthcare Access
subclass of: Father
subclass of: Mother
type: NamedIndividual
type: NodeShape
definition: The party who provides or is capabable of providing consent for another to have a medical treatment or procedure.

Other Consenting Party
type: Class
subclass of: Consenting Party
type: NamedIndividual
type: NodeShape
comment: A Consenting Party that is not Mother, Father or Legally Authorized Representative

Chinese
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: NodeShape
comment: This class denotes Chinese
notation: HHEAR_826
note: This indicates the Chinese ethnicity and was included in the ontology in the context of a study in Suriname

Creole
type: Class
subclass of: Non-White Non-Hispanic
type: NamedIndividual
type: NodeShape
comment: This class denotes Creole
notation: HHEAR_827
note: Entity to represent Creole ethnicity in the context of a study based in Suriname

Hindustani
type: Class
subclass of: Non-White Non-Hispanic
type: NamedIndividual
type: NodeShape
comment: This class denotes Hindustani
notation: HHEAR_828
note: Entity to represent Hindustani ethnicity in the context of a study based in Suriname

Indigenous
type: Class
subclass of: Non-Hispanic Ethnicity
type: NamedIndividual
type: NodeShape
comment: This class denotes Indigenous
notation: HHEAR_829
note: Entity represents the ethnicity of the indigenous people of Suriname. This was defined in the context of a study in Suriname.
scope note: Indigineous to Suriname

Javanese
type: Class
subclass of: Non-White Non-Hispanic
type: NamedIndividual
type: NodeShape
comment: This class denotes Javanese
notation: HHEAR_830
note: Entity represents Javanese ethnicity. Defined in the context of a study in Suriname.

Maroon
type: Class
subclass of: Black Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Maroon
notation: HHEAR_931
note: The entity represents the Maroon ethnicity. This was defined in the context of a study in Suriname.

Mixed Ethnicity
type: Class
subclass of: SIO_001014
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Mixed Ethnicity
alternative label: Mixed (ethnicity)
notation: HHEAR_831
note: Entity defines mixed ethnicity and was included in the context of a study in Suriname

Married or living together with partner
type: Class
equivalent class: Class
  union of: Married
  union of: Domestic Partnership
subclass of: SIO_000287
subclass of: Class
  union of: Married
  union of: Domestic Partnership
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Married or living together with partner
notation: HHEAR_1104

Single/widow or living separated
type: Class
equivalent class: Class
  union of: Widowed
  union of: Separated
  union of: Unmarried
subclass of: SIO_000287
subclass of: Class
  union of: Widowed
  union of: Separated
  union of: Unmarried
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Single/widow or living separated
notation: HHEAR_1105

Bayley Scales of Infant and Toddler Development
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
comment: A protocol published by psychologist Nancy Bayley to evaluate the developmental maturation of human beings within 1-42 months of age
note: The Bayley Scales is in practice for several decades as a useful tool for detecting early developmental delay in clinical and research settings.[5] In 1969, Nancy Bayley published the first BSID. The first BSID assessed motor and mental domains in the age group from 3 to 28 months. BSID 2nd edition published in 1993 added behavior rating scale and widened the age group from 1 to 42 months. BSID -III published in 2006 assessed development from 1 to 42 months in 5 domains - cognition, motor, language, socio-emotional, and adaptive behavior. BSID 4 was published in 2019 and is in current use. BSID 4 retained the five domains from BSID III. [https://www.ncbi.nlm.nih.gov/books/NBK567715/]

Bayley III
type: Class
subclass of: Bayley Scales of Infant and Toddler Development
type: NamedIndividual
type: NodeShape
comment: This class denotes Bayley III
note: BSID -III published in 2006 assessed development from 1 to 42 months in 5 domains - cognition, motor, language, socio-emotional, and adaptive behavior. [https://www.ncbi.nlm.nih.gov/books/NBK567715/]

Bayley (III) Neurodevelopment
type: Class
subclass of: Bayley III
type: NamedIndividual
type: NodeShape
comment: This class denotes Bayley (III) Neurodevelopment

composite score of the cognitive subscale
type: Class
subclass of: Composite Score
subclass of: Bayley (III) Neurodevelopment
subclass of: EFO_0009098
type: NamedIndividual
type: NodeShape
comment: This class denotes composite score of the cognitive subscale
notation: HHEAR_833

composite score of the socio-emotional subscale
type: Class
subclass of: Composite Score
subclass of: Bayley (III) Neurodevelopment
subclass of: EFO_0009100
type: NamedIndividual
type: NodeShape
comment: This class denotes composite score of the socio-emotional subscale
notation: HHEAR_834

composite score for language composing of the receptive communication and expressive communication subscales
type: Class
subclass of: Composite Score
subclass of: Bayley (III) Neurodevelopment
subclass of: SIO_000969
type: NamedIndividual
type: NodeShape
comment: This class denotes composite score for language composing of the receptive communication and expressive communication subscales
notation: HHEAR_835

Composite score for motor composing of the fine motor and gross motor subscales
type: Class
subclass of: Composite Score
subclass of: Bayley (III) Neurodevelopment
subclass of: SIO_000581
type: NamedIndividual
type: NodeShape
comment: This class denotes Composite score for motor composing of the fine motor and gross motor subscales
notation: HHEAR_836

Perceived Stress Scale - Low Stress
type: Class
subclass of: Perceived Stress Tertile
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Perceived Stress Scale - Low Stress
notation: HHEAR_837
note: This category reflects a score of 0-13. The test is Cohen's Perceived Stress Scale.

Perceived Stress Scale - Moderate Stress
type: Class
subclass of: Perceived Stress Tertile
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Perceived Stress Scale - Moderate Stress
notation: HHEAR_838
note: This category reflects a score of 14-26. The test is Cohen's Perceived Stress Scale.

Perceived Stress Scale - High Stress
type: Class
subclass of: Perceived Stress Tertile
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Perceived Stress Scale - High Stress
notation: HHEAR_839
note: This category reflects a score of 27-40. The test is Cohen's Perceived Stress Scale.

Perceived Stress Sum Score
type: Class
subclass of: Perceived Stress Scale
subclass of: score
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Perceived Stress Sum Score

Perceived Stress Tertile
type: Class
subclass of: Perceived Stress Scale
type: NamedIndividual
type: NodeShape
comment: This class denotes Perceived Stress Tertile

Depression Assessment
type: Class
subclass of: Research or Clinical Assessment Tool
type: NamedIndividual
type: NodeShape
SIO_000215: SIO_000824
comment: This class denotes Depression Assessment
note: Entity minted for the 2018-2254 Demohealth study to cover a 0-20 scale assessment of depression.

Depression Assessment - 0-11 No Depression
type: Class
subclass of: Depression Assessment
type: NamedIndividual
type: NodeShape
comment: This class denotes Depression Assessment - 0-11 No Depression
notation: HHEAR_840
note: This is for a score in the range 0-11.

Depression Assessment - 12-20 Probable Depression
type: Class
subclass of: Depression Assessment - Probable Depression
type: NamedIndividual
type: NodeShape
comment: This class denotes Depression Assessment - 12-20 Probable Depression
notation: HHEAR_841
note: This is for a score in the range 12-20.

Depression Assessment Sum Score
type: Class
subclass of: score
subclass of: Depression Assessment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Depression Assessment Sum Score

Depression Assessment - Probable Depression
type: Class
subclass of: score
subclass of: Depression Assessment
type: NamedIndividual
type: NodeShape
comment: This class denotes Depression Assessment - Probable Depression

Pregnancy or Followup
type: Class
equivalent class: Class
  union of: Pregnancy
  union of: Study Followup
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy or Followup

Diet Quality
type: Class
subclass of: Diet and Nutrition
type: NamedIndividual
type: NodeShape
comment: This class denotes Diet Quality
note: Created in the context of 2017-1863 to cover types of healthy eating.

Healthy Eating Index Score
type: Class
subclass of: score
subclass of: Diet Quality
type: NamedIndividual
type: NodeShape
comment: The Healthy Eating Index (HEI) is a measure of diet quality used to assess how well a set of foods aligns with key recommendations and dietary patterns published in the Dietary Guidelines for Americans (Dietary Guidelines). (Source: https://www.fns.usda.gov/cnpp/healthy-eating-index-hei)
notation: HHEAR_842

Mediterranean Diet (24-hr recall)
type: Class
subclass of: Diet Quality
type: NamedIndividual
type: NodeShape
comment: This class denotes Mediterranean Diet (24-hr recall)
notation: HHEAR_843

Household Members Not Mother and Father
type: Class
subclass of: Household
type: NamedIndividual
type: NodeShape
SIO_000132: SIO_000498
comment: This class denotes Household Members Not Mother and Father

Number of days of Asthma Induced Night Sleeplessness
type: Class
subclass of: Asthma Induced Night Sleeplessness
subclass of: Discover Questionnaire Response
subclass of: SIO_000794
subclass of: Restriction
  on property: intervalDuring
  some values from: Visit
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Number of days during the visit period child woke up at night with a cough, wheeze, shortness of breath or tightness in the chest.

Did Not Wake Up With Cough, Wheeze, Shortness of Breath or Tightness in Chest
type: Class
subclass of: Number of days of Asthma Induced Night Sleeplessness
subclass of: Restriction
  on property: STATO_0000047
  all values from: Datatype
    on datatype: NCIT C25301
    with restrictions: nil
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: No days during the visit period child woke up at night with a cough, wheeze, shortness of breath or tightness in the chest
notation: HHEAR_844

Woke Up With Cough, Wheeze, Shortness of Breath or Tightness in Chest Once
type: Class
subclass of: Number of days of Asthma Induced Night Sleeplessness
subclass of: Restriction
  on property: STATO_0000047
  all values from: Datatype
    on datatype: NCIT C25301
    with restrictions: nil
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: One day during the visit period child woke up at night with a cough, wheeze, shortness of breath or tightness in the chest
notation: HHEAR_845

Woke Up With Cough, Wheeze, Shortness of Breath or Tightness in Chest More Than Once
type: Class
subclass of: Number of days of Asthma Induced Night Sleeplessness
subclass of: Restriction
  on property: STATO_0000047
  all values from: Datatype
    on datatype: NCIT C25301
    with restrictions:
      min inclusive: 2
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: More than one day during the visit period child woke up at night with a cough, wheeze, shortness of breath or tightness in the chest
notation: HHEAR_846

Awake All Night With Cough, Wheeze, Shortness of Breath or Tightness in Chest
type: Class
subclass of: Number of days of Asthma Induced Night Sleeplessness
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Awake all night during the visit period with a cough, wheeze, shortness of breath or tightness in the chest
notation: HHEAR_847

Maximum number of days the child could have reported woken
type: Class
subclass of: Number of days of Asthma Induced Night Sleeplessness
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Maximum number of days in the visit where the child could have a night disturbed by aperiod with a cough, wheeze, shortness of breath or tightness in the chest

Maximum number of days the child could have reported limited activity
type: Class
subclass of: Asthma Induced Activity Limitation Response
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Maximum number of days the child could have reported limited activity
notation: HHEAR_848

Inhaler Use
type: Class
subclass of: Asthma Induced Medical Encounter Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhaler Use

Number of days during the visit period child used a rescue inhaler or nebulizer
type: Class
subclass of: Inhaler Use
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of days during the visit period child used a rescue inhaler or nebulizer

Maximum number of days the child could have reported using a rescue inhaler during the day
type: Class
subclass of: Inhaler Use
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Maximum number of days the child could have reported using a rescue inhaler during the day

How many nights during the visit period did the child use a rescue inhaler or nebulizer?
type: Class
subclass of: Inhaler Use
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes How many nights during the visit period did the child use a rescue inhaler or nebulizer?

Maximum number of days the child could have reported using a rescue inhaler during the night
type: Class
subclass of: Inhaler Use
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Maximum number of days the child could have reported using a rescue inhaler during the night

Asthma Symptoms
type: Class
subclass of: Discover Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Symptoms

Number of days during the visit period child have asthma symptoms
type: Class
subclass of: Asthma Symptoms
subclass of: SIO_000794
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of days during the visit period child have asthma symptoms

Maximum number of days the child could have reported symptoms
type: Class
subclass of: Asthma Symptoms
type: NamedIndividual
type: NodeShape
comment: This class denotes Maximum number of days the child could have reported symptoms

Emergency Department Visit
type: Class
subclass of: Emergency Department or Urgent Care Visit
type: NamedIndividual
type: NodeShape
comment: A visit to an emergency department to address an acute or emergent medical issue

Non-Atopic
type: Class
subclass of: Atopy
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Non-Atopic
notation: HHEAR_872

AM-
type: Class
subclass of: Atopy
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes AM-
notation: HHEAR_873

AM+
type: Class
subclass of: Atopy
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes AM+
notation: HHEAR_874

Three months period before the visit.
type: Class
equivalent class: Class
  intersection of: SIO_000417
  intersection of: Restriction
    on property: hasEnd
    some values from: Visit
subclass of: Three months
type: NamedIndividual
type: NodeShape
comment: A time interval that begins three months prior to a study visit.

Admitted to Hospital Overnight
type: Class
subclass of: Hospital Admission By Duration
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Admitted to Hospital Overnight
notation: HHEAR_1110

Emergency Department or Urgent Care Visit
type: Class
subclass of: Healthcare Access
subclass of: Class
  union of: Emergency Department Visit
  union of: Urgent Care Facility Visit
type: NamedIndividual
type: NodeShape

Number of Overnight Hospital Admissions
type: Class
subclass of: Number of Hospital Admissions
subclass of: Restriction
  on property: SIO_000215
  some values from: Admitted to Hospital Overnight
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of Overnight Hospital Admissions

Number of Emergency Room or Urgent Care Visits
type: Class
subclass of: Healthcare Access
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Emergency Department or Urgent Care Visit
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of Emergency Room or Urgent Care Visits

Other Living Quarters
type: Class
equivalent class: Class
  intersection of: Living Quarters
subclass of: Living Quarters
type: NamedIndividual
type: NodeShape
comment: This is Living Quarters 'other' than a Detached, Duplex/Semi, Row House, Row House End or Apartment
notation: HHEAR_875

Human Dwelling With Tile Or Linoleum Flooring
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes a human dwelling with tile or linoleum flooring
notation: HHEAR_877

Human Dwelling With Hardwood Floor
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Hardwood Floor
notation: HHEAR_878

Human Dwelling With Large Rug Floor Covering
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Large Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Large Rug Floor Covering
notation: HHEAR_879

Human Dwelling With Scatter Rug and Hardwood Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Scatter Rug and Hardwood Floor Coverings
notation: HHEAR_880

Human Dwelling With Scatter Rug and Tile Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Scatter Rug and Tile Floor Coverings
notation: HHEAR_881

Human Dwelling With Large Rug and Hardwood Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Large Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Large Rug and Hardwood Floor Coverings
notation: HHEAR_882

Human Dwelling With Wall to Wall Carpet and Scatter Rug Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
  intersection of: Restriction
    on property: SIO_000053
    some values from: Human Dwelling With Wall to Wall Carpet
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes a Human Dwelling With Wall to Wall Carpet and Scatter Rug Floor Coverings
notation: HHEAR_883

Human Dwelling With Large Rug and Tile Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Large Rug
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Large Rug and Tile Floor Coverings
notation: HHEAR_884

Human Dwelling With Large Rug and Concrete Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Cement Floor
  intersection of: Restriction
    on property: SIO_000053
    some values from: Large Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Large Rug and Concrete Floor Coverings
notation: HHEAR_885

Room Dust
type: Class
equivalent class: Class
  intersection of: Dust
  intersection of: Restriction
    on property: PATO_0002261
    some values from: http://snomed.info/id/223398003
subclass of: Allergen
comment: This class denotes Room Dust

Human Dwelling - Room By Dust Level
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling - Room By Dust Level

Room with no house dust
type: Class
subclass of: Human Dwelling - Room By Dust Level
subclass of: Restriction
  on property: SIO_001303
  some values from: Room Dust
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Room with no house dust
notation: HHEAR_886

Room with some house dust
type: Class
subclass of: Human Dwelling - Room By Dust Level
subclass of: Restriction
  on property: SIO_001304
  some values from: Room Dust
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Room with some house dust
notation: HHEAR_887

Room with a lot of dust
type: Class
subclass of: Human Dwelling - Room By Dust Level
subclass of: Restriction
  on property: SIO_001306
  some values from: Room Dust
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Room with a lot of dust
notation: HHEAR_888

Household Income Not Reported
type: Class
subclass of: Household Income
type: NamedIndividual
type: NodeShape
comment: This class denotes Household Income Not Reported
notation: HHEAR_889

Human Dwelling With Flooring Other Than Fitted Carpet, Hardwood, Large Rug, Scatter Rug, Concrete or Tile
type: Class
equivalent class: Class
  intersection of: Human Dwelling
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Flooring Other Than Fitted Carpet, Hardwood, Large Rug, Scatter Rug, Concrete or Tile
notation: HHEAR_890

Annual Income $20,000 or Less
type: Class
subclass of: Annual Income $24,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 20000
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $20,000 or Less
notation: HHEAR_891

Annual Income $40,000 to $60,000
type: Class
subclass of: Annual Income $30,000 to $60,000
subclass of: Annual Income $40,000 to $74,999
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 60000
subclass of: Restriction
  on property: minValue
  has value: 40000
type: NamedIndividual
type: Quality Value
comment: This class denotes Annual Income $40,000 to $60,000
notation: HHEAR_892

Annual Income $60,000 to $100,000
type: Class
subclass of: Annual Income More Than $60,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 100000
subclass of: Restriction
  on property: minValue
  has value: 60000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income $60,000 to $100,000
notation: HHEAR_893

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: unionOf
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
notation: HHEAR_894

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Hardwood
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Hardwood
notation: HHEAR_895

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug
notation: HHEAR_896

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug and Hardwood
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug and Hardwood
notation: HHEAR_897

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug and Tile/Linoleum
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Scatter Rug and Tile/Linoleum
notation: HHEAR_898

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Tile/Linoleum
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Tile/Linoleum
notation: HHEAR_899

Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Tile/Linoleum and Hardwood
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Wall to Wall Carpet or Large Rug Floor Coverings and Tile/Linoleum and Hardwood
notation: HHEAR_933

Human Dwelling With Tile/Linoleum and Hardwood Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Human Dwelling With Tile/Linoleum and Hardwood Floor Coverings
notation: HHEAR_932

Human Dwelling With Scatter Rug and Tile/Linoleum and Hardwood Floor Coverings
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: Restriction
    on property: SIO_000053
    some values from: Hardwood Flooring
  intersection of: Restriction
    on property: SIO_000053
    some values from: Scatter Rug
  intersection of: Restriction
    on property: SIO_000053
    some values from: Q468402
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: NodeShape
comment: This class denotes Human Dwelling With Scatter Rug and Tile/Linoleum and Hardwood Floor Coverings
notation: HHEAR_900

Pregnancy Baseline
type: Class
subclass of: Study Baseline
subclass of: Restriction
  on property: intervalDuring
  some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: A point in a study set to the initial point which occurs during the study subject's pregnancy.

Pregnancy Followup
type: Class
subclass of: Study Followup
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Baseline
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: A point in a study that occurs after the initial baseline of the study and occurs during the study subject's pregnancy.

Pregnancy Followup 2
type: Class
subclass of: Study Followup 2
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
  intersection of: Restriction
    on property: SIO_000668
    all values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: A point in a study that occurs after the initial follow-up point in the study and occurs during the study subject's pregnancy.

Pregnancy Followup 3B
type: Class
subclass of: Study Followup 3
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 2
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy Followup 3

Pregnancy Followup 4
type: Class
subclass of: Study Followup 4
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 3B
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape

Pregnancy Followup 5
type: Class
subclass of: Study Followup 5
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 4
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy Followup 5

Pregnancy Followup 6
type: Class
subclass of: Study Followup 6
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 5
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy Followup 6

Pregnancy Followup 7
type: Class
subclass of: Study Followup 7
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 6
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy Followup 7

Pregnancy Followup 8
type: Class
subclass of: Study Followup 8
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 7
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes Pregnancy Followup 8

Forty Eight Hours Prior to Baseline
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Baseline

Mulatto
type: Class
subclass of: Mixed Ethnicity
type: NamedIndividual
type: NodeShape
comment: Mulatto is a racial classification to refer to people of mixed African and European ancestry. Its use is considered outdated and offensive in several languages, including English and Dutch, whereas in languages such as Italian, Spanish and Portuguese it is not, and can even be a source of pride. [ https://en.wikipedia.org/wiki/Mulatto ]
notation: HHEAR_901

Amarela
type: Class
subclass of: Mixed Ethnicity
type: NamedIndividual
type: NodeShape
comment: Amarela is a yellow skin color that is one of the Brazilian classifications of race [ https://content.iospress.com/articles/statistical-journal-of-the-iaos/sji180471 ] - originates from people with Asian heritage.
notation: HHEAR_902

Mestizo
type: Class
equivalent class: Class
  intersection of: Hispanic or Latino Ethnicity
  intersection of: Indigenous
subclass of: Mixed Ethnicity
type: NamedIndividual
type: NodeShape
comment: (in Latin America) a man of mixed race, especially one having Spanish and indigenous descent.
notation: HHEAR_904

Amerindian
type: Class
subclass of: Indigenous
type: NamedIndividual
type: NodeShape
comment: a member of one of the indigenous peoples of the Americas (used chiefly in anthropological and linguistic contexts).
notation: HHEAR_905

Ladino
type: Class
subclass of: Mixed Ethnicity
type: NamedIndividual
type: NodeShape
comment: ladino, Westernized Central American person of predominantly mixed Spanish and indigenous descent. In that sense, ladino is synonymous with mestizo. The word ladino is Spanish (meaning “Latin”), and the ladinos of Central America are not to be confused with those Sephardic Jews who speak the Ladino language. [ https://www.britannica.com/topic/Ladino ]
notation: HHEAR_906

Afrodeciente
type: Class
subclass of: Black Non-Hispanic
type: NamedIndividual
type: NodeShape
comment: Of Black African descent
alternative label: Afrodecendente
notation: HHEAR_907

Recruited In Brazil-Salvador
type: Class
subclass of: Population Group by Recruitment Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Brazil-Salvador
notation: HHEAR_908

Recruited In Guatemala
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q774
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Guatemala
notation: HHEAR_909

Recruited In Puerto Rico-Northern Karst
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Puerto Rico-Northern Karst
notation: HHEAR_911

Professional School Degree
type: Class
subclass of: College Graduate
type: NamedIndividual
type: NodeShape
comment: Examples include MD, DDS, DVM, JD
notation: HHEAR_913

Doctoral Degree
type: Class
subclass of: College Graduate
type: NamedIndividual
type: NodeShape
comment: Examples include Ph.D. or Ed.D. .
notation: HHEAR_912

General Educational Development Test (GED)
type: Class
subclass of: High School or Some College
type: NamedIndividual
type: NodeShape
comment: https://ged.com/blog/what-is-a-ged ] After graduating from high school, you will receive a diploma. A diploma is a document stating you’ve completed all the required courses to graduate. Some students in high school are close to finishing and getting a diploma, but don’t quite get there. In those cases, students can take a series of tests that will indicate whether or not they have a high school level of education. This is known as the GED test.
notation: HHEAR_914

Parvovirus Infection
type: Class
subclass of: viral infectious disease
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Parvovirus Infection
notation: HHEAR_1091

Fetal Loss
type: Class
equivalent class: Class
  union of: HP_0003826
  union of: NCIT C112862
  union of: NCIT C112863
subclass of: Pregnancy Complication
type: NamedIndividual
type: NodeShape
comment: stillbirth: Death of the fetus in utero after at least 22 weeks of gestation. The age at which fetal demise is legally classified as a miscarriage varies between countries with the US being 20 gestational weeks and the UK being 24 gestational weeks. The HPO chooses the average of these age ranges. late fetal death: Death of a fetus at 16 weeks, 0 days to 19 weeks, 6 days of gestation. early fetal death: Death of a fetus at 10 weeks, 0 days to 15 weeks, 6 days of gestation. [https://www.ebi.ac.uk/ols4/search?q=fetal+death ]

Fetal Loss within 20 weeks
type: Class
equivalent class: Class
  union of: NCIT C112862
  union of: NCIT C112863
subclass of: Fetal Loss
subclass of: Pregnancy Outcome By Fetal Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: late fetal death: Death of a fetus at 16 weeks, 0 days to 19 weeks, 6 days of gestation. early fetal death: Death of a fetus at 10 weeks, 0 days to 15 weeks, 6 days of gestation. [https://www.ebi.ac.uk/ols4/search?q=fetal+death ]
notation: HHEAR_1083

Low Birth Weight
type: Class
subclass of: Birth Weight
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Low Birth Weight
notation: HHEAR_926

Retired
type: Class
subclass of: Occupation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Retired
notation: HHEAR_927

Intended Conception
type: Class
subclass of: Conceiving Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A conception that was intended
notation: HHEAR_1085

First Pregnancy
type: Class
subclass of: Pregnancy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes First Pregnancy
notation: HHEAR_1077

Placental hypoxia
type: Class
subclass of: placenta disease
subclass of: Restriction
  on property: SIO_000217
  some values from: Hypoxia
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Placental hypoxia
notation: HHEAR_928

Estimated Date of Delivery
type: Class
subclass of: Date of Delivery
type: NamedIndividual
type: NodeShape
comment: This class denotes Estimated Date of Delivery

Occupational, Technical, or Vocational Program
type: Class
subclass of: Technical School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Occupational, Technical, or Vocational Program
notation: HHEAR_920

Left Pulsatility Index
type: Class
subclass of: Pulsatility Index
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: RO_0000052
  some values from: UBERON_0005458
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Left Pulsatility Index
note: relates to the Left Umbilical Artery - UBERON_0005458.

Left Arterial Resistance Index
type: Class
subclass of: Systemic Vascular Resistance
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: RO_0000052
  some values from: UBERON_0005458
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Left Arterial Resistance Index
note: Comes from the Left Umbilical Artery - UBERON_0005458.

Right Arterial Resistance Index
type: Class
subclass of: Systemic Vascular Resistance
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: RO_0000052
  some values from: UBERON_0005470
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Right Arterial Resistance Index
note: Comes from the Right Umbilical Artery - UBERON_0005470.

Eight-item Patient Health Questionnaire
type: Class
subclass of: Questionnaire
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: This class denotes Eight-item Patient Health Questionnaire
alternative label: Eight-item Patient Health Questionnaire Depression Scale
note: The PHQ-8 as a measure of current depression in the general population. See https://pubmed.ncbi.nlm.nih.gov/18752852/

Pregnancy Baseline 2
type: Class
subclass of: Study Baseline
subclass of: Restriction
  on property: intervalDuring
  some values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study set to the initial point which occurs during the study subject's pregnancy.

Pregnancy Followup 1B
type: Class
subclass of: Study Followup
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Baseline 2
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after the initial baseline of the study and occurs during the study subject's pregnancy.

Pregnancy Followup 3
type: Class
subclass of: Study Followup 2
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 3
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
  intersection of: Restriction
    on property: SIO_000668
    all values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after the initial follow-up point in the study and occurs during the study subject's pregnancy.

Sample Collection Followup 2
type: Class
subclass of: Study Followup 2
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after the first followup of the study and occurs when a second followup sample is taken from the subject.

Right Pulsatility Index
type: Class
subclass of: Pulsatility Index
subclass of: Physical And Mental Assessment
subclass of: Restriction
  on property: RO_0000052
  some values from: UBERON_0005470
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Right Pulsatility Index
note: Comes from the Right Umbilical Artery - UBERON_0005470.

Placenta Depth
type: Class
subclass of: placenta morphological measurement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Measurement in cm. perpendicular to the Larger and Shorter Axes of the placenta.

Distance between membrane rupture site and margin
type: Class
subclass of: placenta morphological measurement
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Distance between membrane rupture site and margin

Specific Gravity Corrected Concentration
type: Class
subclass of: SIO_001088
type: NamedIndividual
type: NodeShape
comment: This class denotes Specific Gravity Corrected Concentration

Child's Bedroom
type: Class
subclass of: Bedroom
subclass of: Living Room or Child's Bedroom
subclass of: Living Room or Child's Bedroom or Kitchen
type: NamedIndividual
type: NodeShape
comment: A bedroom in a human dwelling that is specifically for a child or children

Living Room or Child's Bedroom
type: Class
equivalent class: Class
  union of: Living Room
  union of: Child's Bedroom
subclass of: room
subclass of: Room
subclass of: Class
  union of: Living Room
  union of: Child's Bedroom
type: NamedIndividual
type: NodeShape
comment: This class denotes Living Room or Child's Bedroom

Yes, fabric upholstered furniture in the living room or child's bedroom
type: Class
equivalent class: Class
  intersection of: Living Room or Child's Bedroom
  intersection of: Restriction
    on property: NCIT C62355
    some values from: Class
      intersection of: ENVO_01000587
      intersection of: Restriction
        on property: NCIT C62355
        some values from: NCIT C172796
subclass of: fabric upholstered furniture in the living room or child's bedroom
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, fabric upholstered furniture in the living room or child's bedroom
notation: HHEAR_941

Living Room or Child's Bedroom or Kitchen
type: Class
equivalent class: Class
  union of: Living Room
  union of: Kitchen
  union of: Child's Bedroom
subclass of: room
subclass of: Room
subclass of: Class
  union of: Living Room
  union of: Kitchen
  union of: Child's Bedroom
type: NamedIndividual
type: NodeShape
comment: This class denotes Living Room or Child's Bedroom or Kitchen

Yes, roaches live or dead or roach stains in living room OR child bedroom OR kitchen
type: Class
equivalent class: Class
  intersection of: Living Room or Child's Bedroom or Kitchen
  intersection of: Restriction
    on property: NCIT C62355
    some values from: Cockroach
subclass of: roaches live or dead or roach stains in living room OR child bedroom OR kitchen
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, roaches live or dead or roach stains in living room OR child bedroom OR kitchen
notation: HHEAR_942

Yes, mouse droppings in the living room OR child's bedroom OR kitchen
type: Class
equivalent class: Class
  intersection of: Living Room or Child's Bedroom or Kitchen
  intersection of: Restriction
    on property: NCIT C62355
    some values from: Mouse Stool
subclass of: mouse droppings in the living room OR child's bedroom OR kitchen
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, mouse droppings in the living room OR child's bedroom OR kitchen
notation: HHEAR_943

Pet Animal
type: Class
subclass of: Eukaryota
type: NamedIndividual
type: NodeShape
comment: A domesticated animal that is kept as a companion

Pet Cat
type: Class
subclass of: Pet Animal
type: NamedIndividual
type: NodeShape
comment: This class denotes Pet Cat

Pet Dog
type: Class
subclass of: Pet Animal
type: NamedIndividual
type: NodeShape
comment: This class denotes Pet Dog

Pet Rodent
type: Class
subclass of: Pet Animal
type: NamedIndividual
type: NodeShape
comment: This class denotes Pet Rodent

Yes, pets in the household - dog, cat or rodent
type: Class
equivalent class: Class
  intersection of: Human Dwelling
  intersection of: unionOf
subclass of: pets in the household - dog, cat or rodent
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, pets in the household - dog, cat or rodent
notation: HHEAR_946

Room Air Conditioner
type: Class
subclass of: Q11395329
type: NamedIndividual
type: NodeShape
comment: This class denotes Room Air Conditioner

fabric upholstered furniture in the living room or child's bedroom
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes fabric upholstered furniture in the living room or child's bedroom

roaches live or dead or roach stains in living room OR child bedroom OR kitchen
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes roaches live or dead or roach stains in living room OR child bedroom OR kitchen

mouse droppings in the living room OR child's bedroom OR kitchen
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes mouse droppings in the living room OR child's bedroom OR kitchen

Presence of air purifier in the living room or child's bedroom
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Presence of air purifier in the living room or child's bedroom

Presence of room air conditioner living room OR child bedroom OR kitchen
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Presence of room air conditioner living room OR child bedroom OR kitchen

pets in the household - dog, cat or rodent
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes pets in the household - dog, cat or rodent

Yes, presence of air purifier in the living room or child's bedroom
type: Class
equivalent class: Class
  intersection of: Living Room or Child's Bedroom
  intersection of: Restriction
    on property: NCIT C62355
    some values from: Q1196206
subclass of: Presence of air purifier in the living room or child's bedroom
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, presence of air purifier in the living room or child's bedroom
notation: HHEAR_944

Yes, presence of room air conditioner living room OR child bedroom OR kitchen
type: Class
equivalent class: Class
  intersection of: Living Room or Child's Bedroom or Kitchen
  intersection of: Restriction
    on property: NCIT C62355
    some values from: Room Air Conditioner
subclass of: Presence of room air conditioner living room OR child bedroom OR kitchen
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, presence of room air conditioner living room OR child bedroom OR kitchen
notation: HHEAR_945

Evidence of leaks in the roof, broken plaster, peeling paint, cracks or holes on the walls and ceilings
type: Class
subclass of: Housing Characteristic Questionnaire Response
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Evidence of leaks in the roof, broken plaster, peeling paint, cracks or holes on the walls and ceilings

Yes, evidence of leaks in the roof, broken plaster, peeling paint, cracks or holes on the walls and ceilings
type: Class
subclass of: Evidence of leaks in the roof, broken plaster, peeling paint, cracks or holes on the walls and ceilings
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Yes, evidence of leaks in the roof, broken plaster, peeling paint, cracks or holes on the walls and ceilings
notation: HHEAR_947

Two Weeks Prior to Childhood Baseline
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Childhood Baseline
type: NamedIndividual
type: NodeShape
comment: A time interval that begins two weeks prior to a childhood baseline and ends at the beginning of the childhood baseline.

Two Weeks Prior to Childhood Followup
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Childhood Followup
type: NamedIndividual
type: NodeShape
comment: A time interval that begins two weeks prior to a childhood followup and ends at the beginning of the childhood followup.

Two Weeks Prior to Childhood Followup 2
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Childhood Followup 2
type: NamedIndividual
type: NodeShape
comment: A time interval that begins two weeks prior to a second childhood followup and ends at the beginning of the second childhood followup.

symptom days (max) - general symptoms, nocturnal symptoms, and days of slowed activity
type: Class
subclass of: Asthma Symptoms
type: NamedIndividual
type: NodeShape
comment: This class denotes symptom days (max) - general symptoms, nocturnal symptoms, and days of slowed activity

Three months
type: Class
subclass of: duration
subclass of: Class
  intersection of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: This class denotes Three months

Pregnancy Baseline Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Restriction
  on property: intervalDuring
  some values from: Pregnancy or Followup
type: NamedIndividual
type: NodeShape
comment: A time interval at which a baseline sample is collected from a study participant that occurs during pregnancy

Pregnancy Followup 1 Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Baseline Sample Collection
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after the initial baseline sample collection of the pregnancy at which another sample is taken.

Pregnancy Followup 2 Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 1 Sample Collection
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after followup sample collection 1 of the pregnancy at which sample 2 is taken.

Pregnancy Followup 3 Sample Collection
type: Class
subclass of: Sample Collection
subclass of: Class
  intersection of: Restriction
    on property: intervalAfter
    some values from: Pregnancy Followup 2 Sample Collection
  intersection of: Restriction
    on property: intervalDuring
    some values from: Pregnancy
type: NamedIndividual
type: NodeShape
definition: A point in a study that occurs after followup sample collection 2 of the pregnancy at which sample 3 is taken.

Umbilical Cord Measurement
type: Class
subclass of: Clinical Measurement
type: NamedIndividual
type: NodeShape
comment: This class denotes Umbilical Cord Measurement

Attached Umbilical Cord Length
type: Class
subclass of: Umbilical Cord Measurement
subclass of: Class
  intersection of: SIO_000041
  intersection of: Restriction
    on property: part of
    some values from: umbilical cord
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Attached Umbilical Cord Length

Attached Umbilical Cord Width
type: Class
subclass of: Umbilical Cord Measurement
subclass of: Class
  intersection of: SIO_000042
  intersection of: Restriction
    on property: part of
    some values from: umbilical cord
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Attached Umbilical Cord Width

Detached Umbilical Cord Width
type: Class
equivalent class: Class
  intersection of: umbilical cord
  intersection of: SIO_000042
  intersection of: Class
    complement of: Umbilical Cord Measurement
subclass of: Umbilical Cord Measurement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Detached Umbilical Cord Width

Number of Detatched Cords
type: Class
subclass of: Umbilical Cord Measurement
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Detatched Cords
alternative label: Detached Umbilical Cord Count

Detached Umbilical Cord Length
type: Class
equivalent class: Class
  intersection of: umbilical cord
  intersection of: SIO_000041
  intersection of: Class
    complement of: Umbilical Cord Measurement
subclass of: Umbilical Cord Measurement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Detached Umbilical Cord Length

Two Weeks Prior to Baseline
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Weeks Prior to Baseline

Two Weeks Prior to Followup
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Weeks Prior to Followup

Two Weeks Prior to Followup 2
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Weeks Prior to Followup 2

Two Weeks Prior to Followup 3
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Weeks Prior to Followup 3

Two Weeks Prior to Followup 4
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Weeks Prior to Followup 4

Three Months Prior to Baseline
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: This class denotes Three Months Prior to Baseline

Three Months Prior to Followup
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: This class denotes Three Months Prior to Followup

Three Months Prior to Followup 2
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: This class denotes Three Months Prior to Followup 2

Three Months Prior to Followup 3
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: This class denotes Three Months Prior to Followup 3

Three Months Prior to Followup 4
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: This class denotes Three Months Prior to Followup 4

Date of Delivery
type: Class
subclass of: Health Outcome
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: The date at which a pregnancy delivery occurs

Serum Was Collected
type: Class
subclass of: Serum Collection
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that serum was collected during a study event
notation: HHEAR_934

Urine Was Collected
type: Class
subclass of: Urine Collection
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that urine was collected during a study event
notation: HHEAR_935

Asthma Related Health Encounter
type: Class
subclass of: Healthcare Access
type: NamedIndividual
type: NodeShape
comment: Any encounter with health care that is caused or motivated by acute asthma

Number of Days With Asthma Symptoms
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject experienced asthma symptoms

Attention and Executive Functioning Domain
type: Class
subclass of: Developmental Neuropsychological Assessment
type: NamedIndividual
type: NodeShape
comment: The Attention and Executive Functioning domain of the Developmental Neuropsychological Assessment (NEPSY-II)

Auditory Attention and Response Set Subtest
type: Class
subclass of: Attention and Executive Functioning Domain
type: NamedIndividual
type: NodeShape
comment: The Auditory Attention and Response Set subtest in the Attention and Executive Functioning Domain of the Developmental Neuropsychological Assessment (NEPSY-II)

Inhibition Subtest
type: Class
subclass of: Attention and Executive Functioning Domain
type: NamedIndividual
type: NodeShape
comment: The Inhibition subtest in the Attention and Executive Functioning Domain of the Developmental Neuropsychological Assessment (NEPSY-II)

Inhibition Naming Subscale
type: Class
subclass of: Inhibition Subtest
type: NamedIndividual
type: NodeShape
comment: The Inhibition Naming subscale

Inhibition Switching Subscale
type: Class
subclass of: Inhibition Subtest
type: NamedIndividual
type: NodeShape
comment: The Inhibition Switching subscale

Inhibition Inhibition Subscale
type: Class
subclass of: Inhibition Subtest
type: NamedIndividual
type: NodeShape
comment: The Inhibition Inhibition subscale

Percentile Rank
type: Class
subclass of: percentile
type: NamedIndividual
type: NodeShape
comment: The percentile rank (PR) of a given score is the percentage of scores in its frequency distribution that are less than that score. (Source: https://en.wikipedia.org/wiki/Percentile_rank)

Percentile Rank Total Correct
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Correct

Percentile Rank Total Omission Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Omission Errors

Percentile Rank Total Inhibitory Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Inhibitory Errors

Percentile Rank Total Commission Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Commission Errors

Percentile Rank Total Self-Corrected Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Self-Corrected Errors

Percentile Rank Total Uncorrected Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Uncorrected Errors

Percentile Rank Total Errors
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Percentile Rank Total Errors

Scaled Score RS Contrast
type: Class
subclass of: Scaled Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Scaled Score RS Contrast

Scaled Score Completion Time Total
type: Class
subclass of: Scaled Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Scaled Score Completion Time Total

Scaled Score Combined
type: Class
subclass of: Scaled Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Scaled Score Combined

Scaled Score Total Correct
type: Class
subclass of: Scaled Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Scaled Score Total Correct

Scaled Score Total Errors
type: Class
subclass of: Scaled Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Scaled Score Total Errors

Behavior Assessment System for Children Attention Subscale
type: Class
subclass of: Behavior Assessment System for Children, Third Edition
type: NamedIndividual
type: NodeShape
comment: This class denotes Behavior Assessment System for Children Attention Subscale

Behavior Assessment System for Children Hyperactivity Subscale
type: Class
subclass of: Behavior Assessment System for Children, Third Edition
type: NamedIndividual
type: NodeShape
comment: This class denotes Behavior Assessment System for Children Hyperactivity Subscale

Behavior Assessment System for Children Locus of Control Subscale
type: Class
subclass of: Behavior Assessment System for Children, Third Edition
type: NamedIndividual
type: NodeShape
comment: This class denotes Behavior Assessment System for Children Locus of Control Subscale

Multidimensional Anxiety Scale for Children
type: Class
subclass of: Anxiety Scale
type: NamedIndividual
type: NodeShape
comment: This class denotes Multidimensional Anxiety Scale for Children

Confidence Interval Maximum Value
type: Class
subclass of: maximum value
subclass of: Restriction
  on property: SIO_000215
  some values from: confidence interval
type: NamedIndividual
type: NodeShape
comment: The upper bound of some confidence interval

Confidence Interval Minimum Value
type: Class
subclass of: minimum value
subclass of: Restriction
  on property: SIO_000215
  some values from: confidence interval
type: NamedIndividual
type: NodeShape
comment: The lower bound of some confidence interval

Percentile Rank Less Than 2%
type: Class
subclass of: Percentile Rank Less Than Or Equal To 2%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Percentile rank of less than 2%
notation: HHEAR_954

Percentile Rank Between 3% and 5%
type: Class
subclass of: Percentile Rank Between 3% and 10%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 3% and 5%
notation: HHEAR_950

Percentile Rank Between 6% and 10%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 6% and 10%
notation: HHEAR_952

Percentile Rank Between 11% and 25%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 11% and 25%
notation: HHEAR_948

Percentile Rank Between 26% and 50%
type: Class
subclass of: Percentile Rank Between 26% and 75%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 26% and 50%
notation: HHEAR_949

Percentile Rank Between 51% and 75%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 51% and 75%
notation: HHEAR_951

Percentile Rank Greater Than 75%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile greater than 75%
notation: HHEAR_953

Percentile Rank Less Than Or Equal To 2%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Percentile rank of less than or equal to 2%
notation: HHEAR_955

Percentile Rank Between 3% and 10%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 3% and 10%
notation: HHEAR_956

Percentile Rank Between 26% and 75%
type: Class
subclass of: Percentile Rank
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Percentile between 26% and 75%
notation: HHEAR_957

Probability Score
type: Class
subclass of: score
type: NamedIndividual
type: NodeShape
comment: A Probability Score is a measure of how good forecasts are in matching observed outcomes.

Has Received Developmental Neuropsychological Assessment
type: Class
subclass of: Developmental Neuropsychological Assessment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Has Received Developmental Neuropsychological Assessment
notation: HHEAR_959

Has Not Received Developmental Neuropsychological Assessment
type: Class
subclass of: Developmental Neuropsychological Assessment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Has Not Received Developmental Neuropsychological Assessment
notation: HHEAR_958

Owned Single Family House
type: Class
subclass of: Single-Family House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A single family house that is owned (or mortgaged) by the residents living there
notation: HHEAR_963

Rented Single Family House
type: Class
subclass of: Single-Family House
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A single family house that is rented by the residents living there
notation: HHEAR_962

Rented Apartment
type: Class
subclass of: Apartment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: An apartment that is rented by its residents
notation: HHEAR_965

Spirometry Testing
type: Class
subclass of: Study Activity
type: NamedIndividual
type: NodeShape
comment: An event during which a spirometry test occurs

Pre-Bronchodilator Spirometry Testing
type: Class
subclass of: Spirometry Testing
subclass of: Restriction
  on property: intervalBefore
  some values from: Post-Bronchodilator Spirometry Testing
type: NamedIndividual
type: NodeShape
comment: The stage of a spirometry test during which measurements of the subject are taken before the admission of a bronchodilator

Post-Bronchodilator Spirometry Testing
type: Class
subclass of: Spirometry Testing
subclass of: Restriction
  on property: intervalAfter
  some values from: Pre-Bronchodilator Spirometry Testing
type: NamedIndividual
type: NodeShape
comment: The stage of a spirometry test during which measurements of the subject are taken after the admission of a bronchodilator

Dollars Per Month
type: Class
subclass of: rate unit
type: NamedIndividual
type: NodeShape
comment: A unit of measure for dollars per month

Conceiving Activity
type: Class
subclass of: Health Outcome
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: Any activity related to conceiving an offspring

First Child
type: Class
subclass of: First
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The first live born child

Second Child
type: Class
subclass of: Second
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The second live born child

Third Child
type: Class
subclass of: Third
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The third live born child

Fourth Child
type: Class
subclass of: Fourth
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The fourth live born child

Fifth Child
type: Class
subclass of: Fifth
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The fifth live born child

Sixth Child
type: Class
subclass of: Sixth
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The sixth live born child

Seventh Child
type: Class
subclass of: Seventh
subclass of: Child
type: NamedIndividual
type: NodeShape
comment: The seventh live born child

Performing an Occupational Activity
type: Class
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: The act of performing an activity that is in fulfillment of one's occupation

Duration of Occupational Activity
type: Class
subclass of: duration
subclass of: Socioeconomic Status
subclass of: Restriction
  on property: SIO_000215
  some values from: Performing an Occupational Activity
type: NamedIndividual
type: NodeShape
comment: The amount of time spent performing an occupational activity

Workplace
type: Class
subclass of: Socioeconomic Status
subclass of: Location
subclass of: Restriction
  on property: SIO_000145
  some values from: Performing an Occupational Activity
type: NamedIndividual
type: NodeShape
comment: A location where an occupation is performed

Hair Salon
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A workplace where people go to have their hair cut and put into a particular style
notation: HHEAR_972

Loading Dock
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A platform for loading or unloading trucks or freight trains
notation: HHEAR_976

Construction Site
type: Class
subclass of: Workplace
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A construction site is a location where all physical construction activities related to a proposed structure take place
notation: HHEAR_968

Employment Status
type: Class
subclass of: Socioeconomic Status
subclass of: Activity
type: NamedIndividual
type: NodeShape
comment: The status of a person's employment

Retained Employment
type: Class
subclass of: Employment Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The state of having retained the same employment status for a determined length of time
notation: HHEAR_1081

Changed Employment
type: Class
subclass of: Employment Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The state of having changed employment status at some point during a determined length of time
notation: HHEAR_1080

Duration in Current Residence
type: Class
subclass of: duration
subclass of: Housing Characteristic
subclass of: Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: The length of time a subject has lived in their current residence

Human Dwelling By Ownership Status
type: Class
subclass of: Human Dwelling
type: NamedIndividual
type: NodeShape
comment: a facet of Human Dwelling that differentiates by the dwelling's ownership status

Lives in Own Home
type: Class
subclass of: Q7243161
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Designates that a person's primary residence is in a home that they own
notation: HHEAR_983

Lives in Family Home
type: Class
subclass of: Q7243161
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Designates that a person's primary residence is their family's home
notation: HHEAR_984

Lives in Rented House
type: Class
subclass of: Q7243161
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Designates that a person's primary residence is a house that they rent
notation: HHEAR_985

Lives in Rented Apartment
type: Class
subclass of: Q7243161
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Designates that a person's primary residence is an apartment that they rent
notation: HHEAR_986

Lives in Rented Room
type: Class
subclass of: Q7243161
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Designates that a person's primary residence is a single room that they rent
notation: HHEAR_987

Private Water Well
type: Class
subclass of: Q43483
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: a private water well
notation: HHEAR_988

Community Water Well
type: Class
subclass of: Q43483
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: a community water well
notation: HHEAR_989

Bottled or Delivered Water
type: Class
subclass of: Q10713454
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: water that has been packaged and delivered
notation: HHEAR_994

Smoked At Least One Cigarette Per Day For Over a Month
type: Class
subclass of: Ever Smoked
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes smoked at least one cigarette per day for over a month
notation: HHEAR_1082

Smoked Today
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: has smoked a cigarette today
notation: HHEAR_995

Smoked More Than A Week Ago
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: smoked a cigarette more than a week ago
notation: HHEAR_996

Smoked More Than A Month Ago
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: smoked a cigarette more than a month ago
notation: HHEAR_997

Smoked This Week
type: Class
subclass of: Smoker
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: smoked a cigarette this week
notation: HHEAR_998

Smoked Prior to Pregnancy
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes smoked prior to pregnancy
notation: HHEAR_999

Frequency of Second Hand Smoke Exposure
type: Class
subclass of: SIO_001367
subclass of: EFO_0008361
type: NamedIndividual
type: NodeShape
comment: the numeric frequency of second hand smoke exposure over some defined period of time

Drank Alcohol Today
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol today
notation: HHEAR_1000

Drank Alcohol Yesterday
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol yesterday
notation: HHEAR_1001

Drank Alcohol Sometime Last Week
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol sometime last week
notation: HHEAR_1100

Drank Alcohol More Than A Week Ago
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol more than a week ago
notation: HHEAR_1002

Drank Alcohol More Than A Month Ago
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol more than a month ago
notation: HHEAR_1003

Drank Alcohol Prior to Pregnancy
type: Class
subclass of: Consumed Alcohol
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol prior to pregnancy
notation: HHEAR_1099

Frequency of Alcohol Consumption
type: Class
subclass of: Alcohol Use
type: NamedIndividual
type: NodeShape
comment: This class denotes frequency of alcohol consumption

Drinks Per Session
type: Class
subclass of: frequency unit
type: NamedIndividual
type: NodeShape
comment: the number of alcoholic drinks consumed during a drinking session, broadly defined

One Year Prior to Baseline
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalContains
  some values from: One Month Prior to Baseline
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: A time interval that begins one year prior to a study baseline and ends at the beginning of the study baseline.

Birth of Single Child
type: Class
subclass of: Pregnancy Outcome By Birth Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes birth of single child
notation: HHEAR_1004

Birth of Twin Children
type: Class
subclass of: Pregnancy Outcome By Birth Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes birth of twin children
notation: HHEAR_1005

Macerated Stillbirth
type: Class
subclass of: Stillbirth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A stillbirth in which the fetus shows signs of maceration, indicating that fetal death occurred significantly before delivery
notation: HHEAR_1006

Fresh Stillbirth
type: Class
subclass of: Stillbirth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A stillbirth in which the fetus does not show signs of maceration, indicating that fetal death occurred recent to the delivery
notation: HHEAR_1007

Deceased After Birth
type: Class
subclass of: Live Birth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A live birth of a child that died recently after birth
notation: HHEAR_1008

Fetal Death Before 20 Weeks
type: Class
subclass of: Pregnancy Outcome By Fetal Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes fetal death before 20 weeks
notation: HHEAR_1009

Did Not Drink Alcohol
type: Class
subclass of: Did Not Consume Alcohol
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes did not drink alcohol
notation: HHEAR_1010

Drank Alcohol One or Two Days Per Week
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol one or two days per week
notation: HHEAR_1011

Drank Alcohol Less Than One Day Per Week
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol less than one day per week
notation: HHEAR_1013

Drank Alcohol Three or More Days Per Week
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank alcohol three or more days per week
notation: HHEAR_1012

Quantity of Alcohol Consumption
type: Class
subclass of: Alcohol Use
type: NamedIndividual
type: NodeShape
comment: This class denotes quantity of alcohol consumption

Drank One or Two Alcoholic Drinks
type: Class
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: drank one or two alcoholic drinks
notation: HHEAR_1014

Drank No Alcoholic Drinks
type: Class
subclass of: Did Not Consume Alcohol
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: drank no alcoholic drinks
notation: HHEAR_1015

Drank Three to Five Alcoholic Drinks
type: Class
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: drank three to five alcoholic drinks
notation: HHEAR_1016

Drank Six or More Alcoholic Drinks
type: Class
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: drank six or more alcoholic drinks
notation: HHEAR_1017

Pregnancy Outcome By Birth Count
type: Class
subclass of: Pregnancy Outcome
subclass of: SIO_000794
type: NamedIndividual
type: NodeShape
comment: This class denotes pregnancy outcome by birth count

Pregnancy Outcome By Fetal Status
type: Class
subclass of: Pregnancy Outcome
type: NamedIndividual
type: NodeShape
comment: This class denotes pregnancy outcome by fetal status

Uses Pesticide
type: Class
subclass of: Pesticide Usage Exposure
subclass of: Restriction
  on property: SIO_000139
  some values from: Pesticide
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Currently uses or has recently used some pesticide
notation: HHEAR_1021

Pesticide Exposure
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: The potential material exposure that a subject has to any form of pesticide

Flea and Tick Preventative Medicine
type: Class
subclass of: SIO_011126
type: NamedIndividual
type: NodeShape
comment: Medicine that is used on non-human animals to prevent fleas and ticks from staying on them

Flea and Tick Management Exposure
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: The material exposure that a subject has to any form of medicine or other chemical used to manage fleas and ticks on pets

Uses Flea and Tick Preventative Medicine
type: Class
subclass of: Flea and Tick Preventative Medicine Exposure
subclass of: Restriction
  on property: SIO_000139
  some values from: Flea and Tick Preventative Medicine
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Currently uses or has recently used flea and tick preventative medicine on a pet or domestic animal
notation: HHEAR_1022

Uses Flea and Tick Spray
type: Class
subclass of: Flea and Tick Spray Exposure
subclass of: Restriction
  on property: SIO_000139
  some values from: Flea and Tick Spray
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Currently uses or has recently used flea and tick spray on a pet or domestic animal
notation: HHEAR_1023

Flea and Tick Preventative Medicine Exposure
type: Class
subclass of: Flea and Tick Management Exposure
type: NamedIndividual
type: NodeShape
comment: The material exposure that a subject has to medicine or other chemical used to prevent pets from hosting fleas and ticks

Flea and Tick Spray Exposure
type: Class
subclass of: Flea and Tick Management Exposure
type: NamedIndividual
type: NodeShape
comment: The material exposure that a subject has to aerasol chemicals used to kill fleas and ticks currently on a pet

Flea and Tick Spray
type: Class
subclass of: SIO_011126
type: NamedIndividual
type: NodeShape
comment: Aerosol chemical substances that are used on non-human animals to kill fleas and ticks from living on them

Pesticide Usage Exposure
type: Class
subclass of: Pesticide Exposure
type: NamedIndividual
type: NodeShape
comment: The potential material exposure that a subject has to any form of pesticide through their direct use of the pesticide

Pesticide Storage Exposure
type: Class
subclass of: Pesticide Exposure
type: NamedIndividual
type: NodeShape
comment: The potential material exposure that a subject has to any form of pesticide through the home storage of the pesticide

Stores Pesticide At Home
type: Class
subclass of: Pesticide Storage Exposure
subclass of: Restriction
  on property: SIO_000139
  some values from: Pesticide
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Currently or has recently stored some pesticide in the home
notation: HHEAR_1101

Uses Pesticide Inside the Home
type: Class
subclass of: Uses Pesticide
subclass of: Indoor Pesticide Usage Exposure
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Has used pesticides inside the home
notation: HHEAR_1088

Pest Infestation
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: The state or level of pest infestation of a subject's environment

Insects Are A Nuisance In The Home
type: Class
subclass of: Pest Infestation
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Insects (roaches, ants, and other bugs) are a nuisance in the home
notation: HHEAR_1086

Pest Control Treatment
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: Treating a place (home, office, etc.) to kill or prevent the infestation of pests

Home Treated For Insects
type: Class
subclass of: Pest Control Treatment
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject's home (interior and/or exterior) has been treated to control insects
notation: HHEAR_1087

Pest Control Treatment By Location
type: Class
subclass of: Pest Control Treatment
type: NamedIndividual
type: NodeShape
comment: differentiates pest control by the location of the treatments

Inside Home Treated For Insects
type: Class
subclass of: Home Treated For Insects
subclass of: Pest Control Treatment By Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Interior of home treated for insects
notation: HHEAR_1024

Outside Home Treated For Insects
type: Class
subclass of: Home Treated For Insects
subclass of: Pest Control Treatment By Location
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Exterior of home treated for insects
notation: HHEAR_1025

Inside And Outside Home Treated For Insects
type: Class
subclass of: Inside Home Treated For Insects
subclass of: Outside Home Treated For Insects
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Interior and Exterior of home treated for insects
notation: HHEAR_1098

Pest Control Treatment By Provider
type: Class
subclass of: Pest Control Treatment
type: NamedIndividual
type: NodeShape
comment: differentiates pest control by the entity providing the treatment

Pest Control Treatment Provided By Government Entity
type: Class
subclass of: Pest Control Treatment By Provider
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes pest control treatment provided by government entity
notation: HHEAR_1026

Pest Control Treatment Provided By Private Entity
type: Class
subclass of: Pest Control Treatment By Provider
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes pest control treatment provided by private entity
notation: HHEAR_1027

Date of Last Pest Control Treatment
type: Class
subclass of: Environmental Exposure
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: This class denotes date of last pest control treatment

Uses Pesticide On Lawn Or Garden
type: Class
subclass of: Uses Pesticide
subclass of: Outdoor Pesticide Usage Exposure
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: uses pesticides on a home lawn or garden
notation: HHEAR_1028

Date of Last Lawn Or Garden Pesticide Treatment
type: Class
subclass of: Environmental Exposure
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: This class denotes date of last lawn or garden pesticide treatment

Date of Last Pesticide Treatment Inside Home
type: Class
subclass of: Environmental Exposure
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: date of last pesticide treatment inside the home

Mosquito Repellant Exposure
type: Class
subclass of: Environmental Exposure
type: NamedIndividual
type: NodeShape
comment: exposure to mosquito repellants

Uses Personal Mosquito Repellant
type: Class
subclass of: Mosquito Repellant Exposure
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: indicates that a subject uses personal mosquito repellant
notation: HHEAR_1029

Duration of Smoking at Least One Cigarette Per Day
type: Class
subclass of: smoking behavior trait
type: NamedIndividual
type: NodeShape
comment: duration a subject has smoked at least one cigarette per day

Inattentive/Distracted - Off Task Behaviors Total Score
type: Class
subclass of: Total Score
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Inattentive/Distracted - Off Task Behaviors Total Score

Out of Seat/Physical Movement in Seat - Off Task Behaviors
type: Class
subclass of: Total Score
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: This class denotes Out of Seat/Physical Movement in Seat - Off Task Behaviors

Afro-Ecuadorian
type: Class
subclass of: Non-White Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person who identifies as Afro-ecuadorian ethnicity
notation: HHEAR_1030

Percentile Rank Of 0.1%
type: Class
subclass of: Percentile Rank Less Than 2%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 0.1%
notation: HHEAR_1031

Percentile Rank Of 0.4%
type: Class
subclass of: Percentile Rank Less Than 2%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 0.4%
notation: HHEAR_1032

Percentile Rank Of 1%
type: Class
subclass of: Percentile Rank Less Than 2%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 1%
notation: HHEAR_1033

Percentile Rank Of 2%
type: Class
subclass of: Percentile Rank Less Than Or Equal To 2%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 2%
notation: HHEAR_1034

Percentile Rank Of 5%
type: Class
subclass of: Percentile Rank Between 3% and 5%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 5%
notation: HHEAR_1035

Percentile Rank Of 9%
type: Class
subclass of: Percentile Rank Between 3% and 10%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 9%
notation: HHEAR_1036

Percentile Rank Of 16%
type: Class
subclass of: Percentile Rank Between 11% and 25%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 16%
notation: HHEAR_1037

Percentile Rank Of 25%
type: Class
subclass of: Percentile Rank Between 11% and 25%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 25%
notation: HHEAR_1038

Percentile Rank Of 37%
type: Class
subclass of: Percentile Rank Between 26% and 50%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 37%
notation: HHEAR_1039

Percentile Rank Of 50%
type: Class
subclass of: Percentile Rank Between 26% and 50%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 50%
notation: HHEAR_1040

Percentile Rank Of 75%
type: Class
subclass of: Percentile Rank Between 51% and 75%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 75%
notation: HHEAR_1041

Percentile Rank Of 84%
type: Class
subclass of: Percentile Rank Greater Than 75%
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A percentile rank value of 84%
notation: HHEAR_1042

Inhibition Naming Percentile Rank Total Errors
type: Class
subclass of: Inhibition Naming Subscale
subclass of: Percentile Rank Total Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Naming Percentile Rank Total Errors

Inhibition Naming Percentile Rank Total Self-Corrected Errors
type: Class
subclass of: Inhibition Naming Subscale
subclass of: Percentile Rank Total Self-Corrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Naming Percentile Rank Total Self-Corrected Errors

Inhibition Naming Total Uncorrected Errors
type: Class
subclass of: Inhibition Naming Subscale
subclass of: Percentile Rank Total Uncorrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Naming Total Uncorrected Errors

Inhibition Inhibition Percentile Rank Total Self-Corrected Errors
type: Class
subclass of: Inhibition Inhibition Subscale
subclass of: Percentile Rank Total Self-Corrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Inhibition Percentile Rank Total Self-Corrected Errors

Inhibition Inhibition Percentile Rank Total Uncorrected Errors
type: Class
subclass of: Inhibition Inhibition Subscale
subclass of: Percentile Rank Total Uncorrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Inhibition Percentile Rank Total Uncorrected Errors

Inhibition Inhibition Percentile Rank Total Errors
type: Class
subclass of: Inhibition Inhibition Subscale
subclass of: Percentile Rank Total Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Inhibition Percentile Rank Total Errors

Inhibition Switching Percentile Rank Total Self Corrected Errors
type: Class
subclass of: Inhibition Switching Subscale
subclass of: Percentile Rank Total Self-Corrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Switching Percentile Rank Total Self Corrected Errors

Inhibition Switching Percentile Rank Total Uncorrected Errors
type: Class
subclass of: Inhibition Switching Subscale
subclass of: Percentile Rank Total Uncorrected Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Switching Percentile Rank Total Uncorrected Errors

Inhibition Switching Percentile Rank Total Errors
type: Class
subclass of: Inhibition Switching Subscale
subclass of: Percentile Rank Total Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Inhibition Switching Percentile Rank Total Errors

Auditory Attention Percentile Rank Total Correct
type: Class
subclass of: Auditory Attention and Response Set Subtest
subclass of: Percentile Rank Total Correct
type: NamedIndividual
type: NodeShape
comment: This class denotes Auditory Attention Percentile Rank Total Correct

Auditory Attention Percentile Rank Total Omission Errors
type: Class
subclass of: Auditory Attention and Response Set Subtest
subclass of: Percentile Rank Total Omission Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Auditory Attention Percentile Rank Total Omission Errors

Auditory Attention Percentile Rank Total Inhibitory Errors
type: Class
subclass of: Auditory Attention and Response Set Subtest
subclass of: Percentile Rank Total Inhibitory Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Auditory Attention Percentile Rank Total Inhibitory Errors

Auditory Attention Percentile Rank Total Commission Errors
type: Class
subclass of: Auditory Attention and Response Set Subtest
subclass of: Percentile Rank Total Commission Errors
type: NamedIndividual
type: NodeShape
comment: This class denotes Auditory Attention Percentile Rank Total Commission Errors

Physical Activity Between 0 and 2.37 Hours Per Week
type: Class
subclass of: Physical Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Physical Activity Between 0 and 2.37 Hours Per Week
notation: HHEAR_1043

Physical Activity Between 2.38 and 5.88 Hours Per Week
type: Class
subclass of: Physical Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Physical Activity Between 2.38 and 5.88 Hours Per Week
notation: HHEAR_1044

Physical Activity Greater Than 5.88 Hours Per Week
type: Class
subclass of: Physical Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Physical Activity Greater Than 5.88 Hours Per Week
notation: HHEAR_1045

Age From 40 to 49 Years Old
type: Class
subclass of: Age of 18 Years or Older
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their fortieth year and ending at the end of their forty ninth year.
notation: HHEAR_1049

Age From 50 to 59 Years Old
type: Class
subclass of: Age of 18 Years or Older
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their fiftieth year and ending at the end of their fifty ninth year.
notation: HHEAR_1050

Age From 60 to 69 Years Old
type: Class
subclass of: Age of 18 Years or Older
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their sixtieth year and ending at the end of their sixty ninth year.
notation: HHEAR_1051

Age From 70 Years Old
type: Class
subclass of: Age of 18 Years or Older
type: NamedIndividual
type: Quality Value
type: Facet Value
type: NodeShape
comment: The age range of a subject starting at the beginning of their seventieth year.
notation: HHEAR_1052

Socioeconomic Status Index Quartile 1
type: Class
subclass of: Socioeconomic Status Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Socioeconomic Status Index Quartile 1
notation: HHEAR_1053

Socioeconomic Status Index Quartile 2
type: Class
subclass of: Socioeconomic Status Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Socioeconomic Status Index Quartile 2
notation: HHEAR_1054

Socioeconomic Status Index Quartile 3
type: Class
subclass of: Socioeconomic Status Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Socioeconomic Status Index Quartile 3
notation: HHEAR_1055

Socioeconomic Status Index Quartile 4
type: Class
subclass of: Socioeconomic Status Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Socioeconomic Status Index Quartile 4
notation: HHEAR_1056

Non-Steroidal Anti-inflammatory Drug Use
type: Class
subclass of: Pharmacotherapy
subclass of: Restriction
  on property: SIO_000230
  some values from: non-steroidal anti-inflammatory drug
type: NamedIndividual
type: NodeShape
comment: This class denotes Non-Steroidal Anti-inflammatory Drug Use

Uses Non-Steroidal Anti-Inflammatory Drugs
type: Class
subclass of: Non-Steroidal Anti-inflammatory Drug Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Uses Non-Steroidal Anti-Inflammatory Drugs
notation: HHEAR_1057

Statin Use
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: NodeShape
comment: This class denotes Statin Use

Uses Statins Regularly
type: Class
subclass of: Statin Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Uses Statins Regularly
notation: HHEAR_1058

Uses Statins Intermittently
type: Class
subclass of: Statin Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Uses Statins Intermittently
notation: HHEAR_1059

Ever Received Hormone Therapy
type: Class
subclass of: Hormone Therapy
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Ever Received Hormone Therapy
notation: HHEAR_1060

Number of Biomarkers
type: Class
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: biomarker
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of Biomarkers

Number of Inflammatory Biomarkers
type: Class
subclass of: Number of Biomarkers
subclass of: Restriction
  on property: SIO_000215
  some values from: inflammatory response
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of Inflammatory Biomarkers

Above Median Number of Inflammatory Biomarkers Present
type: Class
subclass of: Number of Inflammatory Biomarkers
disjoint with: Below Median Number of Inflammatory Biomarkers Present
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Above Median Number of Inflammatory Biomarkers Present
notation: HHEAR_1089

Below Median Number of Inflammatory Biomarkers Present
type: Class
subclass of: Number of Inflammatory Biomarkers
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Below Median Number of Inflammatory Biomarkers Present
notation: HHEAR_1090

Number of B-Cell Activation Biomarkers
type: Class
subclass of: Number of Biomarkers
subclass of: Restriction
  on property: SIO_000215
  some values from: B-Cell Activation
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of B-Cell Activation Biomarkers

Above Median Number of B-Cell Activation Biomarkers Present
type: Class
subclass of: Number of B-Cell Activation Biomarkers
disjoint with: Below Median Number of B-Cell Activation Biomarkers Present
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Above Median Number of B-Cell Activation Biomarkers Present
notation: HHEAR_1092

Below Median Number of B-Cell Activation Biomarkers Present
type: Class
subclass of: Number of B-Cell Activation Biomarkers
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Below Median Number of B-Cell Activation Biomarkers Present
notation: HHEAR_1093

Number of T-Cell Activation Biomarkers
type: Class
subclass of: Number of Biomarkers
subclass of: Restriction
  on property: SIO_000215
  some values from: T-Cell Activation
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of T-Cell Activation Biomarkers

Above Median Number of T-Cell Activation Biomarkers Present
type: Class
subclass of: Number of T-Cell Activation Biomarkers
disjoint with: Below Median Number of T-Cell Activation Biomarkers Present
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Above Median Number of T-Cell Activation Biomarkers Present
notation: HHEAR_1094

Below Median Number of T-Cell Activation Biomarkers Present
type: Class
subclass of: Number of T-Cell Activation Biomarkers
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Below Median Number of T-Cell Activation Biomarkers Present
notation: HHEAR_1095

Number of Th1 Activation Biomarkers
type: Class
subclass of: Number of Biomarkers
subclass of: Restriction
  on property: SIO_000215
  some values from: T-helper 1 cell activation
type: NamedIndividual
type: NodeShape
comment: This class denotes Number of Th1 Activation Biomarkers

Above Median Number of Th1 Activation Biomarkers Present
type: Class
subclass of: Number of Th1 Activation Biomarkers
disjoint with: Below Median Number of Th1 Activation Biomarkers Present
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Above Median Number of Th1 Activation Biomarkers Present
notation: HHEAR_1096

Below Median Number of Th1 Activation Biomarkers Present
type: Class
subclass of: Number of Th1 Activation Biomarkers
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Below Median Number of Th1 Activation Biomarkers Present
notation: HHEAR_1097

Bayley Testing
type: Class
subclass of: Study Activity
subclass of: Restriction
  on property: SIO_000668
  some values from: Bayley Scales of Infant and Toddler Development
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
definition: The time period when the Bayley testing is administered to a subject.

Forty Eight Hours Prior to Followup
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Annual Income $90,001 to $120,000
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup

Forty Eight Hours Prior to Followup 2
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 2

Forty Eight Hours Prior to Followup 3
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 3
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 3

Forty Eight Hours Prior to Followup 4
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 4
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 4

Forty Eight Hours Prior to Followup 5
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 5
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 5

Forty Eight Hours Prior to Followup 6
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 6
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 6

Forty Eight Hours Prior to Followup 7
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 7
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 7

Forty Eight Hours Prior to Followup 8
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 8
type: NamedIndividual
type: NodeShape
comment: This class denotes Forty Eight Hours Prior to Followup 8

Recruited In Nicaragua
type: Class
subclass of: Population Group by Recruitment Location
subclass of: Restriction
  on property: SIO_000668
  has value: Q811
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A population group of study participants that were recruited in Nicaragua
notation: HHEAR_910

Smoking Status By Last Occurrence
type: Class
subclass of: Smoking Status
type: NamedIndividual
type: NodeShape
comment: This class denotes Smoking Status By Last Occurrence

Outdoor Pesticide Usage Exposure
type: Class
subclass of: Pesticide Usage Exposure
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: Exposure to pesticides that occurs from their usage outdoors.

Indoor Pesticide Usage Exposure
type: Class
subclass of: Pesticide Usage Exposure
type: NamedIndividual
type: Quality Variable
type: NodeShape
comment: Exposure to pesticides that occurs from their usage indoors.

Two Months Prior to Baseline
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Baseline
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Months Prior to Baseline

Two Months Prior to Followup
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Months Prior to Followup

Two Months Prior to Followup 2
type: Class
subclass of: duration
subclass of: Restriction
  on property: intervalMeets
  some values from: Study Followup 2
type: NamedIndividual
type: NodeShape
comment: This class denotes Two Months Prior to Followup 2

Distance From Umbilical Cord To Placental Edge
type: Class
subclass of: Umbilical Cord Measurement
subclass of: SIO_000041
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The distance from the umbilical cord to the edge of the placenta. Normally, the umbilical cord is attached to the center of the placenta, but unusual placements can occur. Marginal cord insertion occurs when the umbilical cord is within two centimeters or less from the edge of the placenta. The umbilical cord is still attached, just not in the center. Source: https://my.clevelandclinic.org/health/diseases/23318-marginal-cord-insertion

Hospital Admission By Duration
type: Class
subclass of: Hospital Admission
type: NamedIndividual
type: NodeShape
comment: A subclass of Hospital Admission that facets admissions by their duration.

Urgent Care Facility Visit
type: Class
subclass of: Emergency Department or Urgent Care Visit
type: NamedIndividual
type: NodeShape
comment: A visit to an urgent care center to address an acute or emergent medical issue

Visited Emergency Department or Urgent Care Facility
type: Class
subclass of: Emergency Department or Urgent Care Visit
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject visited an emergency department or urgent care facility; typically during a specified time period.
notation: HHEAR_1111

National Asthma Education and Prevention Program Test Score
type: Class
subclass of: score
subclass of: Physical And Mental Assessment
type: NamedIndividual
type: NodeShape
comment: A test score for an asthma test based on the National Asthma Education and Prevention Program recommendations

Mild Severity Asthma Score
type: Class
subclass of: National Asthma Education and Prevention Program Test Score
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A test score for an asthma test based on the National Asthma Education and Prevention Program recommendations that indicates a subject's asthma is mildly severe.
notation: HHEAR_1107

Intermittent Severity Asthma Score
type: Class
subclass of: National Asthma Education and Prevention Program Test Score
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A test score for an asthma test based on the National Asthma Education and Prevention Program recommendations that indicates a subject's asthma is intermittently severe.
notation: HHEAR_1106

Moderate Severity Asthma Score
type: Class
subclass of: National Asthma Education and Prevention Program Test Score
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A test score for an asthma test based on the National Asthma Education and Prevention Program recommendations that indicates a subject's asthma is moderately severe.
notation: HHEAR_1108

Severe Severity Asthma Score
type: Class
subclass of: National Asthma Education and Prevention Program Test Score
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A test score for an asthma test based on the National Asthma Education and Prevention Program recommendations that indicates a subject's asthma is highly severe.
notation: HHEAR_1109

Pre FEV1/FVC Ratio
type: Class
subclass of: forced expiratory volume to forced vital capacity ratio
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Pre FEV1/FVC Ratio

Post FEV1/FVC Ratio
type: Class
subclass of: forced expiratory volume to forced vital capacity ratio
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Post FEV1/FVC Ratio

FEV1/FVC Z-Score
type: Class
subclass of: respiratory system measurement
subclass of: Z-Score
type: NamedIndividual
type: NodeShape
comment: The Z-Score of a ratio of the spirometry FEV1 to FVC measurement for a subject

Pre FEV1/FVC Z-Score
type: Class
subclass of: FEV1/FVC Z-Score
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The Z-Score of a ratio of the spirometry FEV1 to FVC measurement for a subject prior to inhaler administration.

Post FEV1/FVC Z-Score
type: Class
subclass of: FEV1/FVC Z-Score
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The Z-Score of a ratio of the spirometry FEV1 to FVC measurement for a subject after inhaler administration.

Blank Corrected Concentration
type: Class
subclass of: SIO_001088
type: NamedIndividual
type: NodeShape
comment: A concentration measurement of an analyte in an assay that has been blank corrected. According to the ASI Standards, "When a request comes through for a certified reference material that is “ultra-low”, i.e. below 1 ppm, there is a risk of going below the detection limit and limit of quantification of the instrument. A blank solvent is used to minimize this error. "Impurities of the blank are not counted (assumed to be 0 ppb or ppm) into the calculation of the check standard/standards. The analyte is added to the “solvent blank” when preparing the standards. When the analysis is conducted, a correction value must be used to subtract the effect of the blank on the standards. This reduces the impact of the limit of detection and limit of quantification of the instrument on the results of the calibration as well as ensures the linearity and accuracy of the calibration curve." (Source: https://info.asistandards.com/blog/what-is-blank-correction)

Asthma Control Test Score for 8 to 18 Years
type: Class
subclass of: Asthma Control Test Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Control Test Score for 8 to 18 Years

Asthma Control Test Score for 12 to 18 Years
type: Class
subclass of: Asthma Control Test Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Control Test Score for 12 to 18 Years

Asthma Control Test Score for 8 to 11 Years
type: Class
subclass of: Asthma Control Test Score
type: NamedIndividual
type: NodeShape
comment: This class denotes Asthma Control Test Score for 8 to 11 Years

Number of Nights of Albuterol Use
type: Class
subclass of: Prescription Medication and Dietary Supplements
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Uses Albuterol Inhaler
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes Number of Nights of Albuterol Use

Less Than Grade 8
type: Class
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Completed less than Grade 7
notation: HHEAR_1112

Asthma Severity
type: Class
subclass of: Clinical Observations Severity
type: NamedIndividual
type: NodeShape
comment: A rating or measure of the severity of acute or chronic asthma in a subject

FEF 25-75 Best Value (post-bronchodilator administration)
type: Class
subclass of: FEF 25-75 Best Value
type: NamedIndividual
type: Quantity Variable
comment: This class denotes FEF 25-75 Best Value (post-bronchodilator administration)

FEF 25-75 Best Value (pre-bronchodilator administration)
type: Class
subclass of: FEF 25-75 Best Value
type: NamedIndividual
type: Quantity Variable
comment: This class denotes FEF 25-75 Best Value (pre-bronchodilator administration)

Number of Living Children
type: Class
subclass of: Demographic
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Child
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The number of living children for a subject at a point in time

Bathroom With Shower Count
type: Class
subclass of: Bathroom Count
type: NamedIndividual
type: NodeShape
comment: The total number of bathrooms that include a shower in a house

Residential Building With Heating
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Restriction
    on property: SIO_000028
    some values from: Q11880006
subclass of: Residential Building
subclass of: Restriction
  on property: SIO_000028
  some values from: Q11880006
disjoint with: Residential Building Without Heating
type: NamedIndividual
type: NodeShape
comment: A residential building that contains equipment for heating the living areas

Residential Building Without Heating
type: Class
equivalent class: Class
  intersection of: Residential Building
  intersection of: Class
    complement of: Restriction
      on property: SIO_000028
      some values from: Q11880006
subclass of: Residential Building
subclass of: Class
  complement of: Restriction
    on property: SIO_000028
    some values from: Q11880006
type: NamedIndividual
type: NodeShape
comment: A residential building that does not have heating equipment to warm the living areas

Five or Fewer Light Bulbs
type: Class
subclass of: Light Bulb Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A count of five or fewer light bulbs
notation: HHEAR_1119

Six to Ten Light Bulbs
type: Class
subclass of: Light Bulb Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A count of six to ten light bulbs
notation: HHEAR_1120

Eleven to Fifteen Light Bulbs
type: Class
subclass of: Light Bulb Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A count of eleven to fifteen light bulbs
notation: HHEAR_1121

Sixteen to Twenty Light Bulbs
type: Class
subclass of: Light Bulb Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A count of sixteen to twenty light bulbs
notation: HHEAR_1122

Twenty One or More Light Bulbs
type: Class
subclass of: Light Bulb Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A count of twenty one or more light bulbs
notation: HHEAR_1123

Human Dwelling with Ground or Cement Floor
type: Class
subclass of: Human Dwelling By Floor Covering Type
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A human dwelling (house, apartment, etc.) with a floor that is either the dirt or cement
notation: HHEAR_1145

Household Has a Vacuum Cleaner
type: Class
subclass of: Vacuum Cleaner Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household owns, rents, or has exclusive access to a vacuum cleaner
notation: HHEAR_1124

Household Does Not Have a Vacuum Cleaner
type: Class
subclass of: Vacuum Cleaner Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not own, rent, or have exclusive access to a vacuum cleaner
notation: HHEAR_1125

Household Has a Washing Machine
type: Class
subclass of: Washing Machine Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has a washing machine
notation: HHEAR_1126

Household Does Not Have a Washing Machine
type: Class
subclass of: Washing Machine Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have a washing machine
notation: HHEAR_1127

Household Has a Microwave Oven
type: Class
subclass of: Microwave Oven Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has at least one microwave oven.
notation: HHEAR_1128

Household Does Not Have a Microwave Oven
type: Class
subclass of: Microwave Oven Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have a microwave oven.
notation: HHEAR_1129

Household Has a Toaster
type: Class
subclass of: Toaster Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has at least one toaster.
notation: HHEAR_1130

Household Does Not Have a Toaster
type: Class
subclass of: Toaster Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have a toaster.
notation: HHEAR_1131

Household Has a Personal Computer
type: Class
subclass of: Personal Computer Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has at least one personal computer.
notation: HHEAR_1132

Household Does Not Have a Personal Computer
type: Class
subclass of: Personal Computer Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have a personal computer.
notation: HHEAR_1133

Household Has a Boiler
type: Class
subclass of: Boiler Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has at least one boiler device for heating water.
notation: HHEAR_1134

Household Does Not Have a Boiler
type: Class
subclass of: Boiler Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have a boiler device for heating water.
notation: HHEAR_1135

Received Some Post High School Education
type: Class
subclass of: Graduated From High School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has completed high school and has received some post high school education.
notation: HHEAR_1136

Birth Outcome By Gestational Age
type: Class
subclass of: Birth Outcome
type: NamedIndividual
type: NodeShape
comment: The outcome of a birth faceted by the gestational age of the fetus, either Pre-term Birth or Full-term Birth.

Some Parent Employed
type: Class
subclass of: Employment Status
disjoint with: No Parent Employed
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that at least one parent or caregiver is employed.
notation: HHEAR_1137

No Parent Employed
type: Class
subclass of: Employment Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that no parent or caregiver is employed.
notation: HHEAR_1138

Birth Weight Z-Score
type: Class
subclass of: Z-Score
subclass of: Restriction
  on property: wasDerivedFrom
  some values from: Birth Weight
type: NamedIndividual
type: NodeShape
comment: The Z score of a subject's birth weight

Age at First Lower Respiratory Tract Infection
type: Class
subclass of: Health Outcome
subclass of: SIO_001013
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The age at which a subject contracts their first lower respiratory tract infection

First Lower Respiratory Tract Infection Occurred Before One Year
type: Class
subclass of: Age at First Lower Respiratory Tract Infection
type: NamedIndividual
type: NodeShape
comment: Indicates that a subject's first lower respiratory tract infection occurred before they were one year old.

Diagnosis Year
type: Class
subclass of: SIO_000428
type: NamedIndividual
type: NodeShape
comment: The year in which a subject is diagnosed with a condition

Adulthood Baseline
type: Class
subclass of: Study Baseline
subclass of: Restriction
  on property: intervalDuring
  some values from: Adulthood Period
type: NamedIndividual
type: NodeShape
comment: A study baseline that occurs during the Adulthood Period of a subject

Adulthood Followup
type: Class
subclass of: Study Followup
subclass of: Restriction
  on property: intervalDuring
  some values from: Adulthood Period
type: NamedIndividual
type: NodeShape
comment: A study followup that occurs during the Adulthood Period of a subject

Number of Lower Respiratory Tract Infections
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
subclass of: Restriction
  on property: SIO_000215
  some values from: Lower Respiratory Tract Infection
type: NamedIndividual
type: NodeShape
comment: The number of lower respiratory tract infections contracted by a subject during a specified period of time

AMAI Socioeconomic Levels Index
type: Class
subclass of: Socioeconomic Status Index
type: NamedIndividual
type: NodeShape
comment: The Mexican Association of Market Intelligence and Opinion Agencies (AMAI) Socioeconomic Levels Index (NSE)

AMAI Socioeconomic Status Level A/B
type: Class
subclass of: High Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level A/B

AMAI Socioeconomic Status Level C+
type: Class
subclass of: High Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level C+

AMAI Socioeconomic Status Level C
type: Class
subclass of: Medium Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level C

AMAI Socioeconomic Status Level C-
type: Class
subclass of: Medium Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level C-

AMAI Socioeconomic Status Level D+
type: Class
subclass of: Medium Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level D+

AMAI Socioeconomic Status Level D
type: Class
subclass of: Low Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level D

AMAI Socioeconomic Status Level E
type: Class
subclass of: Low Socioeconomic Status
type: NamedIndividual
type: NodeShape
comment: This class denotes AMAI Socioeconomic Status Level E

High Socioeconomic Status
type: Class
subclass of: AMAI Socioeconomic Levels Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes High Socioeconomic Status
notation: HHEAR_1139

Medium Socioeconomic Status
type: Class
subclass of: AMAI Socioeconomic Levels Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Medium Socioeconomic Status
notation: HHEAR_1141

Low Socioeconomic Status
type: Class
subclass of: AMAI Socioeconomic Levels Index
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Low Socioeconomic Status
notation: HHEAR_1140

Time Since Last Visit
type: Class
subclass of: duration
type: NamedIndividual
type: NodeShape
comment: The elapsed time since the last study visit for a subject

Reactive Hyperemia Percent Change
type: Class
subclass of: Measurement
subclass of: Restriction
  on property: SIO_000215
  some values from: reactive hyperemia
type: NamedIndividual
type: NodeShape
comment: Reactive Hyperemia Percent Change is a measurement of the severity of reactive hyperemia obtained by noting the percentage increase in blood flow to a tissue or organ after a period of temporary blood flow restriction.

Forced Vital Capacity (pre-bronchodilator administration)
type: Class
subclass of: forced vital capacity (FVC)
type: NamedIndividual
type: NodeShape
comment: This class denotes Forced Vital Capacity (pre-bronchodilator administration)

Forced Vital Capacity (post-bronchodilator administration)
type: Class
subclass of: forced vital capacity (FVC)
type: NamedIndividual
type: NodeShape
comment: This class denotes Forced Vital Capacity (post-bronchodilator administration)

Forced Expiratory Volume (pre-bronchodilator administration)
type: Class
subclass of: forced expiratory volume
type: NamedIndividual
type: NodeShape
comment: This class denotes Forced Expiratory Volume (pre-bronchodilator administration)

Forced Expiratory Volume (post-bronchodilator administration)
type: Class
subclass of: forced expiratory volume
type: NamedIndividual
type: NodeShape
comment: This class denotes Forced Expiratory Volume (post-bronchodilator administration)

Case Control Study Match Identifier
type: Class
subclass of: SIO_000115
type: NamedIndividual
type: NodeShape
comment: An identifier used in a matched case control study to determine the distinct sets of subjects sharing the same outcome of interest.

Gram Per Day
type: Class
subclass of: rate unit
type: NamedIndividual
type: NodeShape
comment: This class denotes Gram Per Day

Household Income - Annual Income - South African Rand
type: Class
subclass of: Household Income
type: NamedIndividual
type: NodeShape
comment: This class denotes Household Income - Annual Income - South African Rand

Annual Income Less Than 1,000 ZAR
type: Class
subclass of: Household Income - Annual Income - South African Rand
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: ZAR
subclass of: Restriction
  on property: maxValue
  has value: 1000
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income Less Than 1,000 ZAR
notation: HHEAR_1147

Annual Income 1,000 ZAR to 5,000 ZAR
type: Class
subclass of: Household Income - Annual Income - South African Rand
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: ZAR
subclass of: Restriction
  on property: maxValue
  has value: 5000
subclass of: Restriction
  on property: minValue
  has value: 1000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income 1,000 ZAR to 5,000 ZAR
notation: HHEAR_1148

Annual Income More Than 5,000 ZAR
type: Class
subclass of: Household Income - Annual Income - South African Rand
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: ZAR
subclass of: Restriction
  on property: minValue
  has value: 5000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Annual Income More Than 5,000 ZAR
notation: HHEAR_1149

Household Has a Video or DVD Player
type: Class
subclass of: DVD Player Count
disjoint with: Household Does Not Have a Video or DVD Player
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household has at least one video or DVD player.
notation: HHEAR_1142

Household Does Not Have a Video or DVD Player
type: Class
subclass of: DVD Player Count
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a household does not have at least one video or DVD player.
notation: HHEAR_1143

Childhood Spirometry Testing
type: Class
subclass of: Spirometry Testing
subclass of: Restriction
  on property: intervalDuring
  some values from: Childhood Period
type: NamedIndividual
type: NodeShape
comment: An occurrence of Spirometry Testing that takes place during some Childhood Period

One Year Prior to Childhood Spirometry Testing
type: Class
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalMeets
  some values from: Childhood Spirometry Testing
type: NamedIndividual
type: NodeShape
comment: The time period that begins one year prior to a Childhood Spirometry Testing event and ends at the commencement of the testing event.

Number of Days With Cough Not From a Cold
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject experienced coughing that was not due to a cold

Number of Days With Asthma Symptoms after Running or Climbing Stairs
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject experienced coughing, wheezing, or chest tightness after running or going up stairs

Number of Days When Asthma Symptoms Impacted Play or Other Activities
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject had to slow down or stop his/her activities while at home or playing with other children because of asthma symptoms

Number of Days When Wheezing Prevented Speaking More Than One or Two Words Between Breaths
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject could only speak one or two words at a time between breaths due to wheezing from asthma

Number of Days of Rescue Inhaler Use
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000794
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The total number of days (in some time period) when a subject used a rescue inhaler at least once

PCB105 + PCB127
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 32598-14-4_39635-33-1
notation: PCB105_PCB127

PCB110
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38380-03-9
notation: PCB110

PCB114 + PCB122
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 74472-37-0_76842-07-4
notation: PCB114_PCB122

PCB118 + PCB106
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 31508-00-6_70424-69-0
notation: PCB118_PCB106

PCB128
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38380-07-3
notation: PCB128

PCB137
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 35694-06-5
notation: PCB137

PCB138 + PCB158
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 35065-28-2_74472-42-7
notation: PCB138_PCB158

PCB146 + PCB161
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 51908-16-8_74472-43-8
notation: PCB146_PCB161

PCB156
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38380-08-4
notation: PCB156

PCB157
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 69782-90-7
notation: PCB157

PCB167
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-72-6
notation: PCB167

PCB170
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 35065-30-6
notation: PCB170

PCB172 + PCB192
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-74-8
notation: PCB172_PCB192

PCB177
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-70-4
notation: PCB177

PCB18 + PCB17
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 37680-65-2_37680-66-3
notation: PCB18_PCB17

PCB182 + PCB187
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 60145-23-5_52663-68-0
notation: PCB182_PCB187

PCB183
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-69-1
notation: PCB183

PCB194
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 35694-08-7
notation: PCB194

PCB195
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-78-2
notation: PCB195

PCB196 + PCB203
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 42740-50-1_52663-76-0
notation: PCB196_PCB203

PCB199
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-75-9
notation: PCB199

PCB202
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 2136-99-4
notation: PCB202

PCB206
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 40186-72-9
notation: PCB206

PCB208
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-77-1
notation: PCB208

PCB209
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 2051-24-3
notation: PCB209

PCB22
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38444-85-8
notation: PCB22

PCB31 + PCB28
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 16606-02-3_7012-37-5
notation: PCB31_PCB28

PCB33 + PCB20
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38444-86-9_38444-84-7
notation: PCB33_PCB20

PCB37
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38444-90-5
notation: PCB37

PCB41 + PCB64
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 52663-59-9_52663-58-8
notation: PCB41_PCB64

PCB44
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 41464-39-5
notation: PCB44

PCB47 + PCB48 + PCB75
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes a polychlorobiphenyl compound identified by the CAS Number: 2437-79-8_70362-47-9_32598-12-2
notation: PCB47_48_75

PCB49 + PCB43
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 41464-40-8_70362-46-8
notation: PCB49_PCB43

PCB5 + PCB8
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 16605-91-7_34883-43-7
notation: PCB5_PCB8

PCB52 + PCB73
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 35693-99-3_74338-23-1
notation: PCB52_PCB73

PCB70 + PCB76
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 32598-11-1_70362-48-0
notation: PCB70_PCB76

PCB73 + PCB95
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 74338-23-1_38379-99-6
notation: PCB73_PCB95

PCB74 + PCB61
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 32690-93-0_33284-53-6
notation: PCB74_PCB61

PCB85 + PCB120
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 65510-45-4_68194-12-7
notation: PCB85_PCB120

PCB90 + PCB101 + PCB89
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: This class denotes a polychlorobiphenyl compound identified by the CAS Number: 68194-07-0_37680-73-2_73575-57-2
notation: PCB90_101_89

PCB99
type: Class
subclass of: Polychlorobiphenyl
type: NamedIndividual
type: Facet Value
comment: CAS Number: 38380-01-7
notation: PCB99

WHO Child Growth Standard
type: Class
subclass of: SIO_000442
type: NamedIndividual
type: NodeShape
comment: This class denotes WHO Child Growth Standard, taken from https://www.who.int/tools/child-growth-standards/standards/weight-for-age

WHO Weighted Z-Score
type: Class
subclass of: Birth Outcome
subclass of: Birth Weight Z-Score
subclass of: SIO_001245
subclass of: Class
  intersection of: SIO_001245
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: Birth Weight
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: WHO Child Growth Standard
  intersection of: Restriction
    on property: wasDerivedFrom
    some values from: EFO_0005112
type: NamedIndividual
type: Quantity Variable
was approved by: PER-Jeanette-Stingone
definition: Derived from Birth Weight, Gestational Age, and Child Sex

Time Since Last Birth
type: Class
subclass of: duration
type: NamedIndividual
type: NodeShape
comment: The elapsed time since the last time a person gave birth

Age at Menarche
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_001013
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: The age at menarche for a subject

Less Than Two Years Since Last Birth
type: Class
subclass of: Time Since Last Birth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Less than two years since the subject's last childbirth
notation: HHEAR_1150

Two Years or More Since Last Birth
type: Class
subclass of: Time Since Last Birth
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Two years or more since the subject's last childbirth
notation: HHEAR_1151

DMPA Use
type: Class
subclass of: Pharmacotherapy
type: NamedIndividual
type: NodeShape
comment: This attribute is used to indicate the status of a subject's use of the contraceptive Depot Medroxyprogesterone Acetate (DPMA).

Has Used DMPA
type: Class
subclass of: DMPA Use
disjoint with: Has Never Used DMPA
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has used or continues to use the contraceptive Depot Medroxyprogesterone Acetate (DMPA).
notation: HHEAR_1152

Has Never Used DMPA
type: Class
subclass of: DMPA Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has never used the contraceptive Depot Medroxyprogesterone Acetate (DMPA).
notation: HHEAR_1153

Menarche At or Before Age 10
type: Class
subclass of: Age at Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject's first menstruation occurred at or before age 10.
notation: HHEAR_1154

Menarche At Age 11
type: Class
subclass of: Age at Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject's first menstruation occurred at age 11 years old.
notation: HHEAR_1155

Menarche At Age 12
type: Class
subclass of: Age at Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject's first menstruation occurred at age 12 years old.
notation: HHEAR_1156

Menarche At Age 13
type: Class
subclass of: Age at Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject's first menstruation occurred at age 13 years old.
notation: HHEAR_1157

Menarche At or After Age 14
type: Class
subclass of: Age at Menarche
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject's first menstruation occurred at or after age 14 years old.
notation: HHEAR_1158

Breastfed Less Than Six Months
type: Class
subclass of: Duration of Breast Feeding
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has breastfed their child for less than six months.
notation: HHEAR_1159

Breastfed At Least Six Months
type: Class
subclass of: Duration of Breast Feeding
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has breastfed their child for at least six months.
notation: HHEAR_1160

Annual Income $20,000 to $50,000
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 50000
subclass of: Restriction
  on property: minValue
  has value: 20000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or subject's household receives between $20,000 and $50,000 as annual income
notation: HHEAR_1161

Drank Fewer Than 10 Drinks or Did Not Drink Alcohol
type: Class
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Drank Fewer Than 10 Drinks or Did Not Drink Alcohol
notation: HHEAR_1162

Drank Six to Eight Alcoholic Drinks
type: Class
subclass of: Drank Six or More Alcoholic Drinks
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank six to eight alcoholic drinks
notation: HHEAR_1163

Drank Four or More Alcoholic Drinks Two to Three Times Per Month
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes drank four or more alcoholic drinks two to three times per month
notation: HHEAR_1164

Drank At Least 6 to 8 Alcoholic Drinks On Days When Drinking Or Four Or More Drinks At Least 2 to 3 Times Per Month
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject drink at least 6-8 drinks on days they drink or 4+ drinks at a single sitting at least 2-3 times a month.
notation: HHEAR_1165

BRIEF Metacognition Index
type: Class
subclass of: Behavior Rating Inventory of Executive Function
type: NamedIndividual
type: NodeShape
comment: An index in in the Behavior Rating Inventory of Executive Function (BRIEF) that measures the metacognition of a subject

BRIEF Behavioral Regulation Scale
type: Class
subclass of: Behavior Rating Inventory of Executive Function
type: NamedIndividual
type: NodeShape
comment: A scale in in the Behavior Rating Inventory of Executive Function (BRIEF) that measures the behavioral regulation of a subject

BRIEF Inhibit Scale
type: Class
subclass of: BRIEF Behavioral Regulation Scale
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to control impulses and to stop engaging in a behavior.

BRIEF Shift Scale
type: Class
subclass of: BRIEF Behavioral Regulation Scale
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to move freely from one activity or situation to another, to tolerate change, or to switch or alternate attention.

BRIEF Emotional Control Scale
type: Class
subclass of: BRIEF Behavioral Regulation Scale
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to regulate emotional responses appropriately.

BRIEF Initiate Scale
type: Class
subclass of: BRIEF Metacognition Index
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to begin an activity and to independently generate ideas or problem-solving strategies.

BRIEF Working Memory Scale
type: Class
subclass of: BRIEF Metacognition Index
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to hold information when completing a task, when encoding information, or when generating goals/plans in a sequential manner.

BRIEF Plan/Organize Scale
type: Class
subclass of: BRIEF Metacognition Index
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to anticipate future events; to set goals; to develop steps; to grasp main ideas; to organize and understand the main points in written or verbal presentations.

BRIEF Organization of Materials Scale
type: Class
subclass of: BRIEF Metacognition Index
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to put order in work, play and storage spaces (e.g., desks, lockers, backpacks, and bedrooms).

BRIEF Monitor Scale
type: Class
subclass of: BRIEF Metacognition Index
type: NamedIndividual
type: NodeShape
comment: A scale that measure's a subject's ability to check work and to assess one's own performance; ability to keep track of the effect of one's own behavior on other people.

BRIEF Global Executive Composite Score
type: Class
subclass of: Composite Score
subclass of: Behavior Rating Inventory of Executive Function
type: NamedIndividual
type: NodeShape
comment: A composite score obtained from a combination of the BRIEF Behavioral Regulation Scale and the BRIEF Metacognition Scale

Active Most of the Time
type: Class
subclass of: Physical Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject is active most of the time
notation: HHEAR_1166

Active Some of the Time
type: Class
subclass of: Active Some of the Time or Hardly At All
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject is active some of the time
notation: HHEAR_1167

Active Hardly At All
type: Class
subclass of: Active Some of the Time or Hardly At All
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject is active hardly at all
notation: HHEAR_1168

Active Some of the Time or Hardly At All
type: Class
equivalent class: Class
  union of: Active Some of the Time
  union of: Active Hardly At All
subclass of: Physical Activity
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject is active some of the time or hardly at all
notation: HHEAR_1169

Annual Income $10,000 or Less
type: Class
subclass of: Annual Income $14,999 or Less
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 10000
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes a subject or subject's household has an annual income that is at or below $10,000.
notation: HHEAR_1170

Annual Income $60,000 to $69,999
type: Class
subclass of: Annual Income $40,001 to $70,000
subclass of: Annual Income $60,000 to $74,999
subclass of: Annual Income $60,000 to $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 69999
subclass of: Restriction
  on property: minValue
  has value: 60000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or subject's household has an annual income between $60,000 and $69,999.
notation: HHEAR_1171

Annual Income $70,000 to $79,999
type: Class
subclass of: Annual Income $50,000 to $99,999
subclass of: Annual Income More Than $65,000
subclass of: Annual Income $60,000 to $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 79999
subclass of: Restriction
  on property: minValue
  has value: 70000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or subject's household has an annual income between $70,000 and $79,999.
notation: HHEAR_1172

Annual Income $80,000 to $89,999
type: Class
subclass of: Annual Income $75,001 to $90,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 89999
subclass of: Restriction
  on property: minValue
  has value: 80000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or subject's household has an annual income between $80,000 and $89,999.
notation: HHEAR_1173

Annual Income $90,000 to $99,999
type: Class
subclass of: Annual Income $75,000 to $99,999
subclass of: Annual Income $60,000 to $100,000
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 99999
subclass of: Restriction
  on property: minValue
  has value: 90000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or subject's household has an annual income between $90,000 and $99,999.
notation: HHEAR_1174

Child behavior checklist-autism spectrum
type: Class
subclass of: COGPO_00109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Child behavior checklist-autism spectrum

Child behavior checklist-total problems
type: Class
subclass of: COGPO_00109
type: NamedIndividual
type: Quantity Variable
comment: This class denotes Child behavior checklist-total problems

Pre-Pregnancy and First Trimester
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: intervalFinishedBy
    some values from: First Trimester
  intersection of: Restriction
    on property: intervalStartedBy
    some values from: Pre-Pregnancy
subclass of: SIO_000417
subclass of: Restriction
  on property: intervalFinishedBy
  some values from: First Trimester
subclass of: Restriction
  on property: intervalStartedBy
  some values from: Pre-Pregnancy
type: NamedIndividual
type: NodeShape
comment: This class denotes a time interval that begins at the beginning of a subject's pre-pregnancy and ends at the end of their first trimester.

First Urine Collection
type: Class
subclass of: Urine Collection
type: NamedIndividual
type: NodeShape
comment: This class denotes the first sample collection in a series of urine sample collections.

Second Urine Collection
type: Class
subclass of: Urine Collection
subclass of: Restriction
  on property: intervalAfter
  some values from: First Urine Collection
type: NamedIndividual
type: NodeShape
comment: This class denotes the second sample collection in a series of urine sample collections.

Duration of Neonatal ICU Admission
type: Class
subclass of: Duration of Healthcare Facility Admission
subclass of: Restriction
  on property: SIO_000215
  some values from: Admitted to Neonatal ICU
type: NamedIndividual
type: NodeShape
comment: This class denotes the length of time that a subject is admitted into a neonatal intensive care facility.

Neonatal ICU Admission Status
type: Class
subclass of: ICU Admission
type: NamedIndividual
type: NodeShape
comment: This class denotes the status of either being admitted to, or not admitted to a neonatal intensive care unit (NICU). The direct subclasses of this class delineate the positive and negative cases.

Admitted to Neonatal ICU
type: Class
subclass of: Neonatal ICU Admission Status
disjoint with: Not Admitted to Neonatal ICU
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class indicates that a subject has been admitted to a neonatal intensive care unit.
notation: HHEAR_1178

Not Admitted to Neonatal ICU
type: Class
subclass of: Neonatal ICU Admission Status
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class indicates that a subject has not been admitted to a neonatal intensive care unit.
notation: HHEAR_1179

Liver Fat Attenuation
type: Class
subclass of: liver fat morphological measurement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Liver fat attenuation refers to the decrease in Hounsfield Units (HU) on a computed tomography (CT) scan, indicating the presence of fat in the liver. Normal liver tissue typically has an attenuation value around 50-65 HU. When liver fat content increases, the attenuation value decreases, with values below 40 HU often indicating significant fatty infiltration. This decrease in attenuation is due to fat having a lower density than normal liver tissue. Source: Attenuation coefficient (ATT) measurement for liver fat quantification in chronic liver disease Nobuharu Tamaki, Masayuki Kurosaki, Yutaka Yasui, Kaoru Tsuchiya, Namiki Izumi https://pubmed.ncbi.nlm.nih.gov/34165645/

Abdominal Intermuscular Fat Area
type: Class
subclass of: abdominal fat morphological measurement
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Abdominal intermuscular fat area refers to the fat located between muscle groups in the abdomen. Source: Intermuscular Fat: A Review of the Consequences and Causes Odessa Addison, Robin L Marcus, Paul C LaStayo, Alice S Ryan https://pmc.ncbi.nlm.nih.gov/articles/PMC3910392/

Pericardial Fat Volume
type: Class
subclass of: body fat volume
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Pericardial fat volume (PFV) refers to the amount of fat surrounding the heart, within the pericardial sac. Source: Pericardial fat volume is an independent risk factor for the severity of coronary artery disease in patients with preserved ejection fraction Kiyotaka Okura, Koji Maeno, Seiichiro Okura, Hitoshi Takemori, Daishu Toya, Nobuyoshi Tanaka, Shiro Miyayama https://pubmed.ncbi.nlm.nih.gov/24846390/

Abdominal Subcutaneous Fat Volume
type: Class
subclass of: body fat volume
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Abdominal subcutaneous fat volume refers to the amount of fat located just beneath the skin in the abdominal area. Source: Abdominal subcutaneous fat quantification in obese patients from limited field-of-view MRI data Sophia Michel, Nicolas Linder, Tobias Eggebrecht, Alexander Schaudinn, Matthias Blüher, Arne Dietrich, Timm Denecke & Harald Busse https://www.nature.com/articles/s41598-020-75985-8

Energy Adjusted Total Fat Intake
type: Class
subclass of: EFO_0010809
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: Energy-adjusted total fat intake refers to the percentage of total calories consumed from fat, taking into account the overall calorie intake.

Percent Total Fat Intake
type: Class
subclass of: EFO_0007678
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: A measurement of the total fat intake for a subject expressed as a percentage of the subject's total dietary intake

Fish Protein Intake
type: Class
subclass of: EFO_0010810
type: NamedIndividual
type: Quantity Variable
type: NodeShape
comment: This class denotes a measurement of the dietary intake of fish protein for a subject

MET-Minute per Week
type: Class
subclass of: unit
type: NamedIndividual
type: NodeShape
comment: This class denotes the unit of measure Metabolic Equivalent of Task Minute per Week (MET-min/wk) and is used to quantify the amount of physical activity performed by a subject per week. See https://en.wikipedia.org/wiki/Metabolic_equivalent_of_task for further details.
notation: MET-min/wk

Annual Income $39,999 or Less
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 39999
subclass of: Restriction
  on property: minValue
  has value: 0
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or household earns at most $39,999 per year in income.
notation: HHEAR_1182

Annual Income $40,000 to $74,999
type: Class
subclass of: Household Income
subclass of: Restriction
  on property: SIO_000900
  has value: SIO_000428
subclass of: Restriction
  on property: currency
  has value: USD
subclass of: Restriction
  on property: maxValue
  has value: 74999
subclass of: Restriction
  on property: minValue
  has value: 40000
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that a subject or household has an annual income between $40,000 and $74,999.
notation: HHEAR_1181

Drank Between One and Seven Alcoholic Drinks Per Week
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that subject consumed between one and seven alcoholic drinks per week over a specified period of time.
notation: HHEAR_1183

Drank More Than Seven Alcoholic Drinks Per Week
type: Class
subclass of: Frequency of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Denotes that subject consumed more than seven alcoholic drinks per week over a specified period of time.
notation: HHEAR_1184

Northwestern University Site
type: Class
subclass of: Population Group by Study Site
subclass of: Restriction
  on property: SIO_000668
  has value: Q309350
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes Northwestern University Site
notation: HHEAR_1195

University of California, San Francisco Site
type: Class
subclass of: Population Group by Study Site
subclass of: Restriction
  on property: SIO_000668
  has value: Q1061104
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes University of California, San Francisco Site
notation: HHEAR_1196

Drank Alcohol But Does Not Meet Criteria for Heavy Drinker
type: Class
subclass of: Quantity of Alcohol Consumption
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes that a subject has drank alcohol but not with the frequency that would classify them as a heavy drinker.
notation: HHEAR_1200

Umbilical Cord Segment
type: Class
subclass of: anatomical entity
subclass of: Restriction
  on property: SIO_000068
  some values from: umbilical cord
type: NamedIndividual
type: NodeShape
comment: A segment of an umbilical cord

Umbilical Cord Segment 1
type: Class
subclass of: Umbilical Cord Segment
type: NamedIndividual
type: NodeShape
comment: The first of multiple segments of an umbilical cord; this class is used when it is necessary to distinguish between distinct segments of an umbilical cord for modeling purposes.

Umbilical Cord Segment 2
type: Class
subclass of: Umbilical Cord Segment
type: NamedIndividual
type: NodeShape
comment: The second of multiple segments of an umbilical cord; this class is used when it is necessary to distinguish between distinct segments of an umbilical cord for modeling purposes.

Housing Characteristic Questionnaire Response
type: Class
subclass of: Housing Characteristic
subclass of: Questionnaire Response
type: NamedIndividual
type: NodeShape
comment: Responses to questionnaire questions regarding a subject's housing; this class is not related to a specific questionniare but could contain responses from any questionnaire that is used to characterize the state and properties of a subject's housing situation.

Rice Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of rice in their diet.

Fish Sticks Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of fish sticks in their diet.

Oily Fish Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of oily fish in their diet.

Fresh Fish Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of fresh fish in their diet.

Canned Seafood Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of canned seafood in their diet.

Fried Fish Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of fried fish in their diet.

Shell Fish Consumption
type: Class
subclass of: Eating or Drinking
type: NamedIndividual
type: NodeShape
comment: Identifies the status of a subject's consumption of shell fish in their diet.

Kaufman Mental Processing Index
type: Class
subclass of: Questionnaire
subclass of: Restriction
  on property: SIO_000068
  some values from: Kaufman Assessment Battery for Children
type: NamedIndividual
type: NodeShape
comment: A subscale of Kaufman Assessment Battery for Children that is designed to measure the ability to solve problems by remembering and using an ordered series of images or ideas

Modified checklist for autism in toddlers
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: The Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R) is a screener that will ask a series of 20 questions about your child’s behavior. It's intended for toddlers between 16 and 30 months of age. (Source: https://www.autismspeaks.org/screen-your-child)

Autism Observation Scale for Infants
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: The Autism Observation Scale for Infants (AOSI) was developed to detect and monitor early signs of autism as they emerge in high-risk infants (all with an older sibling with an autistic spectrum disorder). (Source: https://pubmed.ncbi.nlm.nih.gov/17874180/)

Asthma Therapy Assessment Questionnaire
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: The Asthma Therapy Assessment Questionnaire (ATAQ) for children and adolescents was developed to assist clinicians and health plans to identify children at risk for adverse outcomes of asthma. ATAQ is a brief, 20-item parent-completed questionnaire that generates indicators of potential care problems in several categories, including symptom control, behavior and attitude barriers, self-efficacy barriers, and communication gaps. Source: Skinner EA, Diette GB, Algatt-Bergstrom PJ, et al. The asthma therapy assessment questionnaire (ATAQ) for children and adolescents. Disease Management. 2004; 7(4): 305-313. https://doi.org/10.1089/dis.2004.7.305

Children's Health Survey for Asthma
type: Class
subclass of: Questionnaire
type: NamedIndividual
type: NodeShape
comment: To assess the functional status and well-being of children with chronic conditions. The development of a measure for children between 5 and 12 years of age with asthma serves as a template for the development of measures for other conditions and is the focus of this paper.The domains addressed in the asthma measure include physical symptoms; the child's physical activity; the child's social activity; the family's social activity; the emotional impact on the child; the emotional impact on the family; and health care utilization. Each domain is represented by a subscale in the measure. Source: Sullivan SA, Olson LM. Developing condition-specific measures of functional status and well-being for children. Clin Perform Qual Health Care. 1995 Jul-Sep;3(3):132-9. PMID: 10151163.

Visit of Sample Collection
type: Class
subclass of: Physical And Mental Assessment
subclass of: SIO_000417
type: NamedIndividual
type: NodeShape
comment: This attribute identifies the visit at which a bio-sample was collected from a subject.

Japanese American
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: A person who is of Japanese American ethnicity
notation: HHEAR_1204

Triferdine
type: Class
subclass of: Vitamin
type: NamedIndividual
type: NodeShape
comment: Drug information IODINE+FOLIC+IRON (TRIFERDINE) GPO Each 1 tablet contains: -Potassium Iodine 196 mcg (Iodine 0.15 mg) -Ferrous Fumarate 185 mg (Iron 60.81 mg) -Folic Acid 0.400 mg Source: http://www.pharmbma.com/drug-list/t/669-triferdine-eng

B7 Vitamin Supplement
type: Class
subclass of: Vitamin B6 or Vitamin B7 or B Complex Vitamin Supplement
type: NamedIndividual
type: Quality Value
comment: This class denotes B7 Vitamin Supplement
notation: HHEAR_1210

B Complex Vitamin Supplement
type: Class
subclass of: Vitamin B6 or Vitamin B7 or B Complex Vitamin Supplement
type: NamedIndividual
type: Quality Value
comment: This class denotes B Complex Vitamin Supplement
notation: HHEAR_1211

Ferrous Fumarate or Ferrous Sulfate
type: Class
equivalent class: Class
  union of: Ferrous fumarate
  union of: Ferrous sulfate
subclass of: Dietary Supplement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This is the union of ferrous fumarate or ferrous sulfate.
notation: HHEAR_1213

Obimin
type: Class
subclass of: Dietary Supplement
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This nutritional supplement has vitamins and minerals to help provide adequate supply of essential nutrients during pregnancy and lactation. (Source: https://www.unilab.com.ph/products/obimin)
notation: HHEAR_1214

Uses Prenatal Vitamins
type: Class
subclass of: Prenatal Vitamin Use
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject uses or has used prenatal vitamins prior to pregnancy.
notation: HHEAR_1219

Completed Primary School
type: Class
subclass of: High School or Less
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has completed primary school.
notation: HHEAR_1220

Completed Middle School
type: Class
subclass of: Some Middle School
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Indicates that a subject has completed middle school.
notation: HHEAR_1221

Thai Yai
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The ethnic group of Thai Yai people, also known as Shan-Gyi or "Greater Shan," who are a large ethnic group of Tai origin primarily inhabiting the Shan State of Myanmar, as well as areas of northern Thailand, Yunnan province in China, and Assam in India.
notation: HHEAR_1224

Lahu Na
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The ethnic group of Southeast Asians that speak the Lahu Na (or Black Lahu) language
notation: HHEAR_1228

Lahu Nyi
type: Class
subclass of: Asian Non-Hispanic
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: The ethnic group of Southeast Asians that speak the Lahu Nyi (or Red Lahu) language
notation: HHEAR_1229

Vitamin B6 or Vitamin B7 or B Complex Vitamin Supplement
type: Class
equivalent class: Class
  union of: B6 Vitamin Supplement
  union of: B7 Vitamin Supplement
  union of: B Complex Vitamin Supplement
subclass of: Vitamin
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This is the union of B6 Vitamin Supplement, B7 Vitamin Supplement, or B Complex Vitamin Supplement.
notation: HHEAR_1212

High Sensitivity C-Reactive Protein Measurement
type: Class
subclass of: Measurement
type: NamedIndividual
type: NodeShape
comment: The determination of the amount of C-reactive protein (CRP) present in a sample through the use of immunonephelometry, immunoturbidimetry, high-sensitivity enzyme-linked immunosorbent assay (ELISA) and/or resonant acoustic profiling (RAP). This test is optimized to measure lower concentrations of CRP than a conventional CRP test. (Source: NCI Thesaurus)

Monopropyl Phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Monopropyl Phthalate
notation: MPRP

bis(1-Chloropropan-2-yl) hydrogen phosphate
type: Class
subclass of: Organophosphorus Flame Retardant
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes bis(1-Chloropropan-2-yl) hydrogen phosphate
notation: BCPP

2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic Acid
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: This class denotes 2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic Acid
notation: OHMINCH

9-hydroxyphenanthrene
type: Class
subclass of: polycyclic hydrocarbon
type: NamedIndividual
type: Facet Value
comment: This class denotes 9-hydroxyphenanthrene
notation: PHEN9

Arsenocholine
type: Class
subclass of: Arsenic Species
type: NamedIndividual
type: Facet Value
comment: This class denotes Arsenocholine
notation: AsC

Tripropyl phosphate
type: Class
subclass of: Organophosphorus Flame Retardant
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Tripropyl phosphate
notation: TPP

4-((Benzyloxy)carbonyl)benzoic acid
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes 4-((Benzyloxy)carbonyl)benzoic acid
notation: MBZTP

mono-isononyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono-isononyl phthalate
notation: mINP

Bisphenol A bis(2,3-dihydroxypropyl) ether
type: Class
subclass of: Phenol
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Bisphenol A bis(2,3-dihydroxypropyl) ether
notation: BADGE2H2O

N-(6-Chloro-3-pyridylmethyl)-N'-cyano-acetamidine
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes N-(6-Chloro-3-pyridylmethyl)-N'-cyano-acetamidine
notation: NDMA

2,3,3,3-Tetrafluoro-2-(heptafluoropropoxy)propanoic acid
type: Class
subclass of: Perfluoroakyl and Polyfluoroalkyl Substance
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid is a perfluorinated compound that is 2-propoxypentanoic acid in which all 11 of the hydrogens attached to carbon atoms have been replaced by fluorine atoms. Used as an alternative to perfluorooctanoic acid in the fluoropolymer industry for years, its widespread environmental distribution, high bioaccumulation capability, and human exposure have caused great concern, particularly as its potential toxicity and health risk is still largely unknown. It is a monocarboxylic acid, a perfluorinated compound and an ether. (Source: Pubchem)
notation: GENX

Monoisopropyl phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes Monoisopropyl phthalate
notation: MiPP

mono (2-ethyl-5-oxohexyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
comment: This class denotes mono (2-ethyl-5-oxohexyl) phthalate
notation: MEOHP

Mono(6-carboxy-2-methylheptyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Quality Value
type: NodeShape
comment: Mono(6-carboxy-2-methylheptyl) phthalate is a phthalic acid monoester obtained by formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of 7-hydroxy-2,6-dimethylheptanoic acid. It is a dicarboxylic acid and a phthalic acid monoester. (Source: PubChem)
notation: MCOP

2, 4'-DDT
type: Class
subclass of: Organochlorine Pesticide
type: NamedIndividual
type: Facet Value
comment: This class denotes 2, 4'-DDT
notation: OPDDT

2-(((6-Oxo-2-propylheptyl)oxy)carbonyl)benzoic Acid
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes 2-(((6-Oxo-2-propylheptyl)oxy)carbonyl)benzoic Acid
notation: MPOHP

2-(6-Hydroxy-2-propylheptoxy)carbonylbenzoic acid
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes 2-(6-Hydroxy-2-propylheptoxy)carbonylbenzoic acid
notation: MPHHP

5-Hydroxyimidacloprid
type: Class
subclass of: Universal Pesticide Metabolite in Urine
type: NamedIndividual
type: NodeShape
comment: CAS #: 155802-61-2
notation: IMI5OH

Mono(2-propyl-6-carboxyhexyl) phthalate
type: Class
subclass of: Phthalate
type: NamedIndividual
type: Facet Value
type: NodeShape
comment: This class denotes Mono(2-propyl-6-carboxyhexyl) phthalate
notation: MPCHP

Datatype
on datatype: float
with restrictions:
  min exclusive: 25.0

Datatype
intersection of: Datatype
  on datatype: float
  with restrictions:
    min exclusive: 25.0
intersection of: Datatype
  on datatype: float
  with restrictions:
    max exclusive: 29.9

Datatype
on datatype: float
with restrictions:
  max exclusive: 18.5

Restriction
on property: SIO_000300
all values from: Datatype
  on datatype: integer
  with restrictions:
    min exclusive: 25

Restriction
on property: SIO_000300
all values from: Datatype
  on datatype: integer
  with restrictions:
    max exclusive: 15

Restriction
on property: SIO_000300
all values from: Datatype
  on datatype: integer
  with restrictions:
    min inclusive: 15
  with restrictions:
    max exclusive: 25

Datatype
on datatype: float
with restrictions:
  max exclusive: 25.0

Datatype
intersection of: Datatype
  on datatype: float
  with restrictions:
    min exclusive: 18.5
intersection of: Datatype
  on datatype: float
  with restrictions:
    max exclusive: 25.0