{"id":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12433","synonym":["thymus gland","thymus organ","Thymus gland structure (body structure)","Thymus Gland","Reticuloendothelial System, Thymus","THYMUS GLAND","THYMUS","Thymus","thymus"],"prefixIRI":"Thesaurus:C12433","definition":["A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute."],"xref":"UBERON:0002370","label":["Thymus Gland"],"prefLabel":"Thymus Gland","subClassOf":["http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13018"],"parents":[{"id":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13018","synonym":["Organ","Organs","organ"],"prefixIRI":"Thesaurus:C13018","definition":["A unique macroscopic (gross) anatomic structure that performs specific functions. It is composed of various tissues.  An organ is part of an anatomic system or a body region. Representative examples include the heart, lung, liver, spleen, and uterus."],"label":["Organ"],"prefLabel":"Organ","subClassOf":["http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12219"],"prefLabelXl":[],"altLabelXl":[],"hiddenLabelXl":[],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"xref":null,"inScheme":[],"created":null,"modified":null,"@id":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13018","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018","ontology":"https://data.bioontology.org/ontologies/NCIT","children":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/children","parents":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/parents","descendants":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/descendants","ancestors":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/ancestors","instances":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/instances","tree":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/tree","notes":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/notes","mappings":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018/mappings","ui":"http://bioportal.bioontology.org/ontologies/NCIT?p=classes&conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C13018","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}],"obsolete":false,"notation":null,"semanticType":[],"cui":[],"inScheme":[],"created":null,"modified":null,"memberOf":[],"altLabelXl":[],"hiddenLabelXl":[],"prefLabelXl":[],"isInActiveScheme":[],"isInActiveCollection":[],"properties":{"https://data.bioontology.org/metadata/prefixIRI":["Thesaurus:C12433"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#NHC0":["C12433"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P97":["A bi-lobed organ surrounded by a connective tissue capsule. It is located in the upper anterior portion of the chest, behind the sternum. It is composed predominantly of lymphocytes and fewer epithelial cells. Connective tissue septa separate the lobes into lobules. The lobules contain an outer portion (cortical zone) which is rich in lymphocytes and an inner portion (medullary zone) which is rich in epithelial cells. It is an organ essential for the development of the immune system. Its function is the maturation of the progenitor lymphoid cells to thymocytes and subsequently to mature T-cells. It reaches its greatest weight at puberty and subsequently begins to involute."],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P325":["A primary lymphoid organ generally located in the mediastinum near the thoracic inlet and/or along lateral aspects of the neck.","An organ that is part of the lymphatic system, in which T lymphocytes grow and multiply. The thymus is in the chest behind the breastbone.","Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop."],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#A32":["http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C70729","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C171435","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C158874","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156422","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156421","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177570"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P366":["Thymus_Gland"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P322":["CDISC","GDC","PCDC","UBERON","mCode"],"http://www.w3.org/2000/01/rdf-schema#label":["Thymus Gland"],"http://www.geneontology.org/formats/oboInOwl#hasDbXref":["UBERON:0002370"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90":["thymus gland","thymus organ","Thymus gland structure (body structure)","Thymus Gland","Reticuloendothelial System, Thymus","THYMUS GLAND","THYMUS","Thymus","thymus"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P207":["C0040113"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P375":["THYMUS","Thymus"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P108":["Thymus Gland"],"http://www.w3.org/1999/02/22-rdf-syntax-ns#type":["http://www.w3.org/2002/07/owl#Class"],"http://www.w3.org/2000/01/rdf-schema#subClassOf":["http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13018"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P107":["Thymus Gland"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#A8":["http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179481","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168656","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77529","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77526","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179483","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193234","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198975","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168660","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179482","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168664","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168663","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C193006","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168655","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C74456","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C168659","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537","http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C179478"],"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106":["Body Part, Organ, or Organ Component"]},"@id":"http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C12433","@type":"http://www.w3.org/2002/07/owl#Class","links":{"self":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433","ontology":"https://data.bioontology.org/ontologies/NCIT","children":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/children","parents":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/parents","descendants":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/descendants","ancestors":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/ancestors","instances":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/instances","tree":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/tree","notes":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/notes","mappings":"https://data.bioontology.org/ontologies/NCIT/classes/http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433/mappings","ui":"http://bioportal.bioontology.org/ontologies/NCIT?p=classes&conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C12433","@context":{"self":"http://www.w3.org/2002/07/owl#Class","ontology":"http://data.bioontology.org/metadata/Ontology","children":"http://www.w3.org/2002/07/owl#Class","parents":"http://www.w3.org/2002/07/owl#Class","descendants":"http://www.w3.org/2002/07/owl#Class","ancestors":"http://www.w3.org/2002/07/owl#Class","instances":"http://data.bioontology.org/metadata/Instance","tree":"http://www.w3.org/2002/07/owl#Class","notes":"http://data.bioontology.org/metadata/Note","mappings":"http://data.bioontology.org/metadata/Mapping","ui":"http://www.w3.org/2002/07/owl#Class"}},"@context":{"@vocab":"http://data.bioontology.org/metadata/","label":"http://www.w3.org/2000/01/rdf-schema#label","prefLabel":"http://www.w3.org/2004/02/skos/core#prefLabel","prefLabelXl":"http://www.w3.org/2008/05/skos-xl#prefLabel","altLabelXl":"http://www.w3.org/2008/05/skos-xl#altLabel","hiddenLabelXl":"http://www.w3.org/2008/05/skos-xl#hiddenLabel","synonym":"http://www.w3.org/2004/02/skos/core#altLabel","definition":"http://www.w3.org/2004/02/skos/core#definition","obsolete":"http://www.w3.org/2002/07/owl#deprecated","notation":"http://www.w3.org/2004/02/skos/core#notation","prefixIRI":"http://data.bioontology.org/metadata/prefixIRI","parents":"http://www.w3.org/2000/01/rdf-schema##<Proc:0x00007f554ad4ae30 /opt/ontoportal/ontologies_api/shared/bundle/ruby/3.2.0/bundler/gems/ontologies_linked_data-867ff0f5194c/lib/ontologies_linked_data/models/class.rb:67 (lambda)>","subClassOf":"http://www.w3.org/2000/01/rdf-schema#subClassOf","semanticType":"http://bioportal.bioontology.org/ontologies/umls/hasSTY","cui":"http://bioportal.bioontology.org/ontologies/umls/cui","xref":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","inScheme":"http://www.w3.org/2004/02/skos/core#inScheme","created":"http://purl.org/dc/terms/created","modified":"http://purl.org/dc/terms/modified","@language":[]}}