untitled-ontology-7
type: Ontology
has_obo_format_version: 1.2

has_obo_format_version
type: AnnotationProperty

Adrenoleukodystrophy
type: Class
subclass of: Leukodystrophy
abbreviation: LDA
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/E71.52 MESH:http://purl.bioontology.org/ontology/MESH/D000326 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10588
id: Adrenoleukodystrophy

Alexander's Disease
type: Class
subclass of: Leukodystrophy
disjoint with: Down's Syndrome
abbreviation: ALEX
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D038261 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_4252
id: Alexanders_Disease

Alpha-Synucleinopathy Disorders
type: Class
subclass of: Progressive Neurodegenerative Diseases
definition: Group of neurodegenerative disorders in which the main pathological observation is abnormal accumulation of alpha-synuclein.
id: Alpha-Synucleinopathy_Disorders

Alzheimer's Disease
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: AD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G30 MESH:http://purl.bioontology.org/ontology/MESH/D000544 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002511 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10652
id: Alzheimers_Disease

Amyotrophic Lateral Sclerosis
type: Class
subclass of: Motor Neuron Diseases
abbreviation: ALS
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G12.21 MESH:http://purl.bioontology.org/ontology/MESH/D000690 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007354 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_332
id: Amyotrophic_Lateral_Sclerosis

Argyrophilic Grain Disease
type: Class
subclass of: Neuropathophysiological Traits
disjoint with: Congophilic Angiopathy
abbreviation: AGD
database cross reference: SNOMEDCT: http://purl.bioontology.org/ontology/SNOMEDCT/230281007
id: Argyrophilic_Grain_Disease

Attention Deficit Hyperactivity Disorder
type: Class
subclass of: Psychiatric Disorders
disjoint with: Autism Spectrum Disorder
abbreviation: ADHD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F90 MESH:http://purl.bioontology.org/ontology/MESH/D001289 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007018 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1094
id: Attention_Deficit_Hyperactivity_Disorder

Atypical Parkinson's Disease
type: Class
subclass of: Alpha-Synucleinopathy Disorders
definition: Patient's who have an alphasynucleinopathy or so called "Lewy body disease", however, they do not have the typical neuropathological picture of PD. In these cases additional neuropathological findings are considered to contribute to the clinical picture. These additional neuropathological findings vary between cases. Hence the "atypical Parkinson's disease"
abbreviation: ATPD
id: Atypical_Parkinsons_Disease

Autism Spectrum Disorder
type: Class
subclass of: Psychiatric Disorders
abbreviation: ASD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/F84.0, http://purl.bioontology.org/ontology/ICD10/F84.1, http://purl.bioontology.org/ontology/ICD10/F84 MESH:http://purl.bioontology.org/ontology/MESH/D000067877 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000717 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060041
id: Autism_Spectrum_Disorder

Autosomal Dominant Cerebellar Ataxia
type: Class
subclass of: Cerebellar Ataxia
disjoint with: Friedreich's Ataxia
abbreviation: ADCA
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10/G11 MESH: http://purl.bioontology.org/ontology/MESH/D002524, http://purl.bioontology.org/ontology/MESH/D001259 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0001251 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_1441, http://purl.obolibrary.org/obo/DOID_0050753
id: Autosomal_Dominant_Cerebellar_Ataxia

Binswanger's Disease
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: BINSW
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D015140
id: Binswangers_Disease

Bipolar Disorder
type: Class
subclass of: Psychiatric Disorders
abbreviation: BP
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F31 MESH:http://purl.bioontology.org/ontology/MESH/D001714 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0007302
id: Bipolar_Disorder

Brain Cancer
type: Class
definition: Category including neoplasms of the brain, both primary (benign/malignant) and secondary (metastatic) forms.
id: Brain_Cancer

C9ORF72
type: Class
subclass of: Mutation
definition: Donors with C9ORF72 mutation mostly show FTD-TDP-B pathology, but FTD-TDP A is also seen.
abbreviation: C9ORF72
id: C9ORF72

Cerebellar Ataxia
type: Class
subclass of: Neurological Disorders
definition: Group of disorders in which the main symptom is ataxia.
abbreviation: ATAXIA
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11 MESH: http://purl.bioontology.org/ontology/MESH/D002524, http://purl.bioontology.org/ontology/MESH/D001259 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050753
id: Cerebellar_Ataxia

CADASIL
type: Class
subclass of: Neurological Disorders
abbreviation: VDCAD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/I67.850 MESH:http://purl.bioontology.org/ontology/MESH/D046589 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_13945
synonym: Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy
id: Cerebral_Autosomal_Dominant_Arteriopathy_with_Sub-cortical_Infarcts_and_Leukoencephalopathy

Cerebrovascular Accident
type: Class
subclass of: Vascular Pathology
disjoint with: Ischemic Changes
abbreviation: CVA
database cross reference: MESH: http://purl.bioontology.org/ontology/MESH/D020521 DOID: http://purl.obolibrary.org/obo/DOID_6713
id: Cerebrovascular_Accident

Congophilic Angiopathy
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: CA
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D016657 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_9246
synonym: cerebral amyloid angiopathy
id: Congophilic_Angiopathy

Control Brain
type: Class
definition: Donors without cognitive decline or dementia, who neuropathologically do not meet the criteria for any neurodegenerative disease.
abbreviation: CON
id: Control_Brain

Corticobasal Degeneration
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: CBD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.85, http://purl.bioontology.org/ontology/ICD10CM/G30-G32
id: Corticobasal_Degeneration

Creutzfeldt-Jakob Disease
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: CJD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/A81.0 MESH:http://purl.bioontology.org/ontology/MESH/D007562, http://purl.bioontology.org/ontology/MESH/D017096 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11949, http://purl.obolibrary.org/obo/DOID_649
id: Creutzfeldt-Jakob_Disease

Dementia
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: DEM
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D003704 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000726 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1307, http://purl.obolibrary.org/obo/DOID_1561
id: Dementia

Dementia with Lewy Bodies
type: Class
subclass of: Alpha-Synucleinopathy Disorders
abbreviation: DLB
database cross reference: Human Disease Ontology:https://disease-ontology.org/?id=DOID:12217 MESH:http://purl.bioontology.org/ontology/MESH/D020961
id: Dementia_with_Lewy_Bodies

Developmental Diseases
type: Class
subclass of: Rare Disorders
abbreviation: DEV
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D002658 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0012759
id: Developmental_Diseases

Diffuse Axonal Injury
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: DAI
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/S06.2, http://purl.bioontology.org/ontology/ICD10/S06 MESH:http://purl.bioontology.org/ontology/MESH/D020833 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0003405
id: Diffuse_Axonal_Injury

Down's Syndrome
type: Class
subclass of: Syndromes
abbreviation: DOWN
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q90, http://purl.bioontology.org/ontology/ICD10CM/Q00-Q99 MESH:http://purl.bioontology.org/ontology/MESH/D004314
id: Downs_Syndrome

Dystonia
type: Class
subclass of: Neurological Disorders
abbreviation: DYSTO
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G24, http://purl.bioontology.org/ontology/ICD10CM/G20-G26 MESH:http://purl.bioontology.org/ontology/MESH/D004421, http://purl.bioontology.org/ontology/MESH/D020820 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0001332
id: Dystonia

Encephalitis
type: Class
subclass of: Neurological Disorders
abbreviation: ENCE
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G04.9 MESH:http://purl.bioontology.org/ontology/MESH/D004660
id: Encephalitis

Encephalopathy
type: Class
subclass of: Neurological Disorders
definition: Group of pathologic disorders that affect the brain, which cannot be more appropriately included in another category/group.
abbreviation: ENCEPHA
id: Encephalopathy

Epilepsy
type: Class
subclass of: Neurological Disorders
abbreviation: EPI
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G40 MESH:http://purl.bioontology.org/ontology/MESH/D004827 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0001250 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1826
id: Epilepsy

Fahr's Syndrome
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: FAHR
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/C536275 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002135 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060230, http://purl.obolibrary.org/obo/DOID_679
id: Fahrs_Syndrome

Fragile X Syndrome
type: Class
subclass of: Syndromes
abbreviation: FRAGX
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/Q99.2 MESH: http://purl.bioontology.org/ontology/MESH/D005600, http://purl.bioontology.org/ontology/MESH/D038901, http://purl.bioontology.org/ontology/MESH/D040181 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_14261, http://purl.obolibrary.org/obo/DOID_0050879
id: Fragile_X_Syndrome

Friedreich's Ataxia
type: Class
subclass of: Cerebellar Ataxia
abbreviation: FA
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11.11 MESH: http://purl.bioontology.org/ontology/MESH/D001259 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0001251
id: Friedreichs_Ataxia

Frontotemporal Dementia
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: FTD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.0 MESH:http://purl.bioontology.org/ontology/MESH/D057174 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002145 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_9255
id: Frontotemporal_Dementia

Frontotemporal Dementia FUS
type: Class
subclass of: Frontotemporal Dementia
disjoint with: Pick's Disease
definition: Frontoterporal lobe degeneration with FUS (Fused in sarcoma) accumulations.
abbreviation: FTD-FUS
id: Frontotemporal_Dementia_FUS

Frontotemporal Dementia TDP
type: Class
subclass of: Frontotemporal Dementia
definition: Donors with frontotomporal lobe degeneration with TDP-43 pathology.
abbreviation: FTD-TDP
database cross reference: https://pubmed.ncbi.nlm.nih.gov/21644037/
id: Frontotemporal_Dementia_TDP

Frontotemporal Dementia TDP type A
type: Class
subclass of: Frontotemporal Dementia TDP
disjoint with: Frontotemporal Dementia TDP type B
definition: FTD with TDP-43 pathology, charactarized by numerous short dystrophic neurites and crescentic or oval neuronal cytoplasmatic inclusions, concentrated primarely in neocortical layer II.
id: Frontotemporal_Dementia_TDP_type_A

Frontotemporal Dementia TDP type B
type: Class
subclass of: Frontotemporal Dementia TDP
definition: FTD with TDP-43 pathology, charactarized by a moderate numbers of neuronal cytoplasmatic inclusions, in all cortical layers, but with only few dystrophic neurites.
id: Frontotemporal_Dementia_TDP_type_B

Frontotemporal Dementia TDP type C
type: Class
subclass of: Frontotemporal Dementia TDP
definition: FTD with TDP-43 pathology, characterized by a predominance of elongated dystrophic neurites in upper cortical layers with only few neuronal cytoplasmatic inclusions.
id: Frontotemporal_Dementia_TDP_type_C

Frontotemporal Dementia Tauopathy
type: Class
subclass of: Frontotemporal Dementia
definition: Donors with FTD characterized by abnormal intracellular accumulation of hyperphosphorilated tau.
abbreviation: FTD-TAU
database cross reference: https://pubmed.ncbi.nlm.nih.gov/27306735/
id: Frontotemporal_Dementia_Tauopathy

Frontotemporal Dementia Ubiquitine
type: Class
subclass of: Frontotemporal Dementia
definition: Donors with frontotemporal lobar degeneration with ubiquitin or P62 only immunoreactive inclusions (negative for all other proteins, as well as cases that have not yet been analyzed with FUS or TDP-43)
abbreviation: FTD-UPS
database cross reference: https://pubmed.ncbi.nlm.nih.gov/21810890/
id: Frontotemporal_Dementia_Ubiquitine

Guillain-Barré Disease
type: Class
subclass of: Polyneuropathy
abbreviation: GUIL
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G61.0 MESH:http://purl.bioontology.org/ontology/MESH/D020275 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_12842
id: Guillain-Barre_Disease

Hereditary Motoric Sensoric Neuropathy
type: Class
subclass of: Polyneuropathy
abbreviation: HMSN
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G60.0 MESH:http://purl.bioontology.org/ontology/MESH/D015417
synonym: Charcot Marie Tooth disease
id: Hereditary_Motoric_Sensoric_Neuropathy

Hereditary Spastic Paraplegia
type: Class
subclass of: Neurological Disorders
abbreviation: HSP
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G11.4 MESH:http://purl.bioontology.org/ontology/MESH/D015419 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002313
id: Hereditary_Spastic_Paraplegia

Hippocampal Sclerosis
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: HIP
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G93.81 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0033715
id: Hippocampal_Sclerosis

Human Immunodeficiency Virus
type: Class
subclass of: Other Disorders with Neurological Implications
abbreviation: HIV
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/B20-B20 MESH:http://purl.bioontology.org/ontology/MESH/D006678
id: Human_Immunodeficiency_Virus

Huntington's Disease
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: HD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G10 MESH:http://purl.bioontology.org/ontology/MESH/D006816 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_12858
id: Huntingtons_Disease

Hydrocephalus Adultorum
type: Class
subclass of: Neurological Disorders
abbreviation: COHA
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G91 MESH:http://purl.bioontology.org/ontology/MESH/D006849 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000238 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10908
id: Hydrocephalus_Adultorum

Incidental Lewy Body Disease
type: Class
subclass of: Alpha-Synucleinopathy Disorders
definition: Incidental Lewy body disease is the presence of Lewy bodies or Lewy neurites without clinical findings of parkinsonism or dementia.
abbreviation: iLBD
id: Incidental_Lewy_Body_Disease

Ischemic Changes
type: Class
subclass of: Vascular Pathology
abbreviation: IS
database cross reference: Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0002637
id: Ischemic_Changes

Klinefelter's Syndrome
type: Class
subclass of: Syndromes
abbreviation: KLIN
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q98.1, http://purl.bioontology.org/ontology/ICD10CM/Q98.0 MESH:http://purl.bioontology.org/ontology/MESH/D007713 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1921
id: Klinefelters_Syndrome

Korsakoff Syndrome
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: KOR
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/E51.2, http://purl.bioontology.org/ontology/ICD10CM/F04 MESH:http://purl.bioontology.org/ontology/MESH/D020915 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10915, http://purl.obolibrary.org/obo/DOID_2384
id: Korsakoff_Syndrome

Leukodystrophy
type: Class
subclass of: Rare Disorders
abbreviation: LD
database cross reference: Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0002415 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10579
id: Leukodystrophy

Major Depressive Disorder
type: Class
subclass of: Psychiatric Disorders
abbreviation: MDD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F32, http://purl.bioontology.org/ontology/ICD10CM/F33 MESH:http://purl.bioontology.org/ontology/MESH/D003865 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000716 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1470
id: Major_Depressive_Disorder

Meningitis
type: Class
subclass of: Neurological Disorders
abbreviation: MEN
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10/G00 MESH:http://purl.bioontology.org/ontology/MESH/D008581 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0001287
id: Meningitis

Metabolic Disease
type: Class
subclass of: Other Disorders with Neurological Implications
abbreviation: MEDIS
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D008659, http://purl.bioontology.org/ontology/MESH/D001928 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0014667
id: Metabolic_Disease

Motor Neuron Diseases
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: MND
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G12.2 MESH:http://purl.bioontology.org/ontology/MESH/D000690 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_231
id: Motor_Neuron_Diseases

Multiple Sclerosis
type: Class
subclass of: Neuroinflammatory Disease
disjoint with: Neuromyelitis Optica
abbreviation: MS
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G35 MESH: http://purl.bioontology.org/ontology/MESH/D009103 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_2377
id: Multiple_Sclerosis

Multiple Sclerosis Primary Progressive
type: Class
subclass of: Multiple Sclerosis
disjoint with: Multiple Sclerosis Remitting Relapsing
abbreviation: MS-PP
database cross reference: Human Disease Ontology: https://disease-ontology.org/?id=DOID:0050784
id: Multiple_Sclerosis_Primary_Progressive

Multiple Sclerosis Remitting Relapsing
type: Class
subclass of: Multiple Sclerosis
abbreviation: MS-RR
database cross reference: Human Disease Ontology: https://disease-ontology.org/?id=DOID:2378
id: Multiple_Sclerosis_Remitting_Relapsing

Multiple Sclerosis Secondary Progressive
type: Class
subclass of: Multiple Sclerosis
abbreviation: MS-SP
database cross reference: Human Disease Ontology: https://disease-ontology.org/?id=DOID:0050783
id: Multiple_Sclerosis_Secondary_Progressive

Multiple System Atrophy
type: Class
subclass of: Alpha-Synucleinopathy Disorders
abbreviation: MSA
database cross reference: MESH: http://purl.bioontology.org/ontology/MESH/D019578 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_4752
id: Multiple_System_Atrophy

Mutation
type: Class
definition: Category including the mutations that occur in donors and that are relevant for understanding their family or clinical history.
id: Mutation

Narcolepsy
type: Class
subclass of: Neurological Disorders
abbreviation: NARCO
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G47.41 MESH:http://purl.bioontology.org/ontology/MESH/D009290 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_535, http://purl.obolibrary.org/obo/DOID_8986
id: Narcolepsy

Neuroinflammatory Disease
type: Class
subclass of: Neurological Disorders
definition: Group of disorders characterized by inflammation in the central nervous system.
abbreviation: AUTO
id: Neuroinflammatory_Disease

Neurological Disorders
type: Class
definition: Category including neurological disorders with various causes (genetic, autoimmune, vascular, infectious). Progressive neurodegenerative disorders form a separate category.
id: Neurological_Disorders

Neuromyelitis Optica
type: Class
subclass of: Neuroinflammatory Disease
abbreviation: NMO
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G36.0 MESH: http://purl.bioontology.org/ontology/MESH/D009471 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_8869
id: Neuromyelitis_Optica

Neuropathophysiological Traits
type: Class
definition: Category including neuropathophysiological traits observed on autopsy.
id: Neuropathophysiological_Traits

Nigral Degeneration
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: NIG
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D013378
id: Nigral_Degeneration

Non-Classifiable Senile Dementia
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: NCSD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F03.9, http://purl.bioontology.org/ontology/ICD10CM/G31.1 Human Phenotype Ontology:http://purl.obolibrary.org/obo/HP_0000726
id: Non-Classifiable_Senile_Dementia

Non-Hodgkin Lymphoma
type: Class
subclass of: Brain Cancer
disjoint with: Space-Occupying Proces or Tumor
abbreviation: NHL
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/C85 MESH: http://purl.bioontology.org/ontology/MESH/D008228 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0012539 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_0060060
id: Non-Hodgkin_Lymphoma

Obsessive Compulsive Disorder
type: Class
subclass of: Psychiatric Disorders
abbreviation: OCD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F42 MESH:http://purl.bioontology.org/ontology/MESH/D009771 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_10933
id: Obsessive_Compulsive_Disorder

Other Disorders with Neurological Implications
type: Class
definition: Category including disorders that may have implications for nervous system structure and function.
id: Other_Disorders_with_Neurological_Implications

PROG
type: Class
subclass of: Mutation
definition: Pathogenic mutation in Progranulin (GRN) gene on chromosome 17.
abbreviation: PROG
id: PROG

Pallidal Degeneration
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: PAL
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/C564910
id: Pallidal_Degeneration

Parkinson's Disease
type: Class
subclass of: Alpha-Synucleinopathy Disorders
disjoint with: Parkinson's Disease with Dementia
abbreviation: PD
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G20 MESH: http://purl.bioontology.org/ontology/MESH/D016631 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0001300, http://purl.obolibrary.org/obo/HP_0100315 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_14330
id: Parkinsons_Disease

Parkinson's Disease with Dementia
type: Class
subclass of: Alpha-Synucleinopathy Disorders
definition: Donors with with clinical and neuropathological PD, and clinical cognitive decline/dementia.
abbreviation: PDD
id: Parkinsons_Disease_with_Dementia

Pick's Disease
type: Class
subclass of: Frontotemporal Dementia
abbreviation: PID
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G31.01 MESH: http://purl.bioontology.org/ontology/MESH/D020774 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11870
id: Picks_Disease

Polyneuropathy
type: Class
subclass of: Neurological Disorders
abbreviation: POLY
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/G60-G65 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1389
id: Polyneuropathy

Post Traumatic Stress Disorder
type: Class
subclass of: Psychiatric Disorders
abbreviation: PTSD
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F43.1 MESH:http://purl.bioontology.org/ontology/MESH/D013313 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_2055
id: Post_Traumatic_Stress_Disorder

Posterior Cortical Atrophy Dementia
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: PCAD
database cross reference: MEDDRA:http://purl.bioontology.org/ontology/MEDDRA/10078207
id: Posterior_Cortical_Atrophy_Dementia

Prader-Willi Syndrome
type: Class
subclass of: Syndromes
abbreviation: PWS
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/Q87.11 MESH:http://purl.bioontology.org/ontology/MESH/D011218 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_11983
id: Prader-Willi_Syndrome

Progressive Multifocal Leucoencephalopathy
type: Class
subclass of: Encephalopathy
abbreviation: PML
database cross reference: Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_643 MESH:http://purl.bioontology.org/ontology/MESH/D007968 ICD10:http://purl.bioontology.org/ontology/ICD10/A81.2
id: Progressive_Multifocal_Leucoencephalopathy

Progressive Neurodegenerative Diseases
type: Class
definition: Category including disorders characterized by progressive dysfunction of the nervous system.
id: Progressive_Neurodegenerative_Diseases

Progressive Supranuclear Palsy
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: PSP
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D013494 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_678
id: Progressive_Supranuclear_Palsy

Psychiatric Disorders
type: Class
definition: Category including psychiatric disorders.
id: Psychiatric_Disorders

Rare Disorders
type: Class
definition: Category including disorders that are infrequently observed in the general population and/or the autopsy cohort.
id: Rare_Disorders

Schizophrenia
type: Class
subclass of: Psychiatric Disorders
abbreviation: SCZ
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/F20 MESH:http://purl.bioontology.org/ontology/MESH/D012559 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_5419
id: Schizophrenia

Senile Involutive Cortical Changes
type: Class
subclass of: Neuropathophysiological Traits
definition: SICC is a term used by the Netherlands Brain Bank since the beginning. At first it was only about the progress of amyloid plagues and neurofibrillary tangles, but not sufficient enough to meet the criteria for Alzheimer’s disease. Over the years, the neuropathological field has developed, and by now SICC encompasses both amyloid plaques (up to Thal phase 3 out of 5) and tangles (Braak 1, 2 and 3), but also ARTAG (age-related tau-astrogliopathy) and mild cerebral amyloid angiopathy. In the present these findings are all written down separately.
abbreviation: SICC
synonym: ARTAG
id: Senile_Involutive_Cortical_Changes

Septic Cerebral Foci
type: Class
subclass of: Vascular Pathology
definition: Donors with cerebral septic lesions and/or a cerebral abcess.
id: Septic_Cerebral_Foci

Spinocerebellar Ataxia
type: Class
subclass of: Cerebellar Ataxia
abbreviation: SCA
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/G11 MESH: http://purl.bioontology.org/ontology/MESH/D020754 Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050753
id: Spinocerebellar_Ataxia

Syndromes
type: Class
subclass of: Rare Disorders
definition: Group of rare syndromes associated with a specific genetic cause.
id: Syndromes

Tauopathy
type: Class
subclass of: Neuropathophysiological Traits
abbreviation: TAU
database cross reference: MESH:http://purl.bioontology.org/ontology/MESH/D024801 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_680
id: Tauopathy

Vascular Dementia
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: VD
database cross reference: DOID: https://disease-ontology.org/?id=DOID:8725 MESH: http://purl.bioontology.org/ontology/MESH/D015140 ICD10: http://purl.bioontology.org/ontology/ICD10CM/F01
id: Vascular_Dementia

Vascular Encephalopathy
type: Class
subclass of: Encephalopathy
definition: Donors with neuropathological vascular lesions (infarctions/atherosclerosis/hemmorhages).
abbreviation: VE
id: Vascular_Encephalopathy

Vascular Pathology
type: Class
subclass of: Neuropathophysiological Traits
definition: Group of traits observed on autopsy related to vascular pathology.
id: Vascular_Pathology

Wernicke Encephalopathy
type: Class
subclass of: Progressive Neurodegenerative Diseases
abbreviation: WER
database cross reference: ICD10:http://purl.bioontology.org/ontology/ICD10CM/E51.2 MESH:http://purl.bioontology.org/ontology/MESH/D014899
id: Wernicke_Encephalopathy

Fragile-X-Associated Tremor/Ataxia Syndrome
type: Class
subclass of: Cerebellar Ataxia
abbreviation: FXTAS
database cross reference: Human Disease Ontology: http://purl.obolibrary.org/obo/DOID_0050879 MESH: http://purl.bioontology.org/ontology/MESH/C564105
id: Fragile-X-Associated_Tremor/Ataxia_Syndrome

Space-Occupying Proces or Tumor
type: Class
subclass of: Brain Cancer
abbreviation: TUM
database cross reference: ICD10: http://purl.bioontology.org/ontology/ICD10CM/R90.0 MESH: http://purl.bioontology.org/ontology/MESH/D001932 Human Phenotype Ontology: http://purl.obolibrary.org/obo/HP_0030692 Human Disease Ontology:http://purl.obolibrary.org/obo/DOID_1319
id: Space-Occupying_Proces/Tumor

Alexander%25252527s disease
id: Alexander%2525252527s_disease

Fahr%25252527s syndrome
id: Fahr%2525252527s_syndrome

Huntington%25252527s disease
id: Huntington%2525252527s_disease

Picks disease
id: Picks_disease