758 78 5 http://purl.obolibrary.org/obo/TXPO_0004072 PLA2G15 (canonical) positively regulator of immune response[Phospholipidosis] 'PLA2G15 (canonical) positively regulator of immune response[Phospholipidosis]' SubClassOf 'has role' some 'positive regulator of immune response' http://purl.obolibrary.org/obo/GO_0062093 lysophagy 'lysophagy' SubClassOf 'occurs in' some 'autophagosome' http://purl.obolibrary.org/obo/TXPO_0001986 mitochondrial damage [toxic course] 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'decreasing mitochondrial membrane potential [Mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Hypofunction of sequestering of calcium ion in ER [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Negative regulation of methionine metabolic process' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing damaged mitochondria [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing lipid concentration' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Calcium ion homeostasis imbalance [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'negative regulation of antioxidant enzyme activation' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'malfunctioning of cytokinesis' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing damaged mitochondria' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0005106 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0005109 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'IL6 signaling [Mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'GJA1 (mol)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'gluconeogenesis [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'cardiolipin peroxidation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing uric acid level [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing PCNA level [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Dysregulation of mitochondrion organization' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'WNT signal transduction pathway' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'neovascularization' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'NRF2(canonical) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'collagen deposition [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'STAT3 activation[Mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'IL-1beta production [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing ACSL1 level [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some '肝細胞再生' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'mitochondrial membrane morphology changes' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Hypofunction of mitochondrial repair [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Malfunctioning of insulin signaling [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing BCL-2 level [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'beta-catenin signal (primitive)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'AMPK(canonical) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'GSK3beta signal transduction pathway' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'negative regulation of phosphorylation' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing CPT1 level [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'TLR4 signaling [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'cell cycle arrest [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PI3K signal transduction pathway' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'lipoperoxidation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'liver cancer dependent molecule (rat)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PHB - inactive form (human) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PHB (mol)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'TLR4 signaling pathway [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing cholesterol level' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'CAR activation [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'NDUFV3 inactovation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'GADD45G (mol)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'hypofunction of anti-oxidative stress[mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'hepatic stellate cell activation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'lipid biosynthetic process [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'CAR activation' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'release of inflammatory DAMPs [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing mitochondrial membrane potential [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increasing HMGB1 level [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PCNA (human) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Negative regulation of glutathione transport into mitochondria' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'inducible nitric oxide synthase production [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'YAP signaling (primitive)' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Insulin resistance (process) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'CDT1 inactivation [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'HIF1A activation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'TGFA (canonical) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'HIF1A(canonical) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'phospholipid peroxidation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'hyperfunction of gluconeogenesis [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PPARA - activation state (mouse) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing demand for response to ER stress [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0005112 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PTPRD gene promoter methylation [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'ketone body biosynthetic process [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'nagative regulation of mitophagy [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'clofibrate [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Increase in mitochondrial calcium level' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'increasing leptin level [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0005115 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0005118 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'necrosis [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'mitochondrial fatty acid beta-oxidation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'positive regulation of autophagy [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some http://purl.obolibrary.org/obo/TXPO_0004985 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'tumorigenesis [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'redox changes [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'PPARGC1A (canonical) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'Snail1 signaling [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'NDUFB6 (human) [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'inflammasome activation [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'mitochondria morphology change [mitochondrial disorder]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'TP53(canonical) [hepatocarcinogenesis]' 'mitochondrial damage [toxic course]' SubClassOf 'has part' some 'GSK3beta signal (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004155 phospholipid homeostasis imbalance [Phospholipidosis (mild) ] 'phospholipid homeostasis imbalance [Phospholipidosis (mild) ]' SubClassOf 'has state' some 'toxicological imbalance SM' http://purl.obolibrary.org/obo/TXPO_0004239 cyclin B1-CDK1 complex - inactive form (canonical)[mitochondrial disorder] 'cyclin B1-CDK1 complex - inactive form (canonical)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0000680 toxicological imbalance ML 'toxicological imbalance ML' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological imbalance ML' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/NCIT_C49508)))) http://purl.obolibrary.org/obo/TXPO_0001683 maintaining phospholipid homeostasis [Phospholipidosis] 'maintaining phospholipid homeostasis [Phospholipidosis]' SubClassOf 'has state' some 'toxicological imbalance M=M (maintining homeostasis in the daily life)' http://purl.obolibrary.org/obo/TXPO_0001768 sphingomyelin metabolism imbalance [Phospholipidosis - genetic- sphingomyelin disorder ] 'sphingomyelin metabolism imbalance [Phospholipidosis - genetic- sphingomyelin disorder ]' SubClassOf 'has state' some 'toxicological imbalance SM' http://purl.obolibrary.org/obo/TXPO_0001743 small (functioning performance value) 'small (functioning performance value)' SubClassOf 'functioning performance value' 'small (functioning performance value)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0004208 http://purl.obolibrary.org/obo/TXPO_0001742 medium (functioning performance value) 'medium (functioning performance value)' SubClassOf 'functioning performance value' 'medium (functioning performance value)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0004208 http://purl.obolibrary.org/obo/TXPO_0001741 large (functioning performance value) 'large (functioning performance value)' SubClassOf 'functioning performance value' http://purl.obolibrary.org/obo/TXPO_0001740 very large (functioning performance value) 'very large (functioning performance value)' SubClassOf 'functioning performance value' 'very large (functioning performance value)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0004208 http://purl.obolibrary.org/obo/TXPO_0001780 toxicological balance L=L (maintining homeostasis) 'toxicological balance L=L (maintining homeostasis)' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological balance L=L (maintining homeostasis)' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological balance L=L (maintining homeostasis)' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/NCIT_C49508)))) 'toxicological balance L=L (maintining homeostasis)' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/NCIT_C49508)))) http://purl.obolibrary.org/obo/TXPO_0001781 toxicological imbalance LVL 'toxicological imbalance LVL' SubClassOf 'toxicological imbalance' 'toxicological imbalance LVL' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological imbalance LVL' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/NCIT_C49508)))) 'toxicological imbalance LVL' SubClassOf 'toxicological imbalance VL (toxic action)' http://purl.obolibrary.org/obo/TXPO_0001777 phospholipid metabolism imbalance [Phospholipidosis (mild)] 'phospholipid metabolism imbalance [Phospholipidosis (mild)]' SubClassOf 'has state' some 'toxicological imbalance ML' 'phospholipid metabolism imbalance [Phospholipidosis (mild)]' SubClassOf 'has state' some 'toxicological imbalance SM' http://purl.obolibrary.org/obo/TXPO_0001776 phospholipid metabolism imbalance [Phospholipidosis - genetic] 'phospholipid metabolism imbalance [Phospholipidosis - genetic]' SubClassOf 'has state' some 'toxicological imbalance SM' 'phospholipid metabolism imbalance [Phospholipidosis - genetic]' SubClassOf 'has state' some ('toxicological imbalance SM' or http://purl.obolibrary.org/obo/TXPO_0002327) http://purl.obolibrary.org/obo/TXPO_0000493 toxicological imbalance SM 'toxicological imbalance SM' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some ('very large (functioning performance value)' or 'large (functioning performance value)' or 'medium (functioning performance value)'))))) 'toxicological imbalance SM' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'medium (functioning performance value)')))) http://purl.obolibrary.org/obo/TXPO_0004498 cyproterone acetate [hepatocarcinogenesis] 'cyproterone acetate [hepatocarcinogenesis]' SubClassOf 'cyproterone acetate' 'cyproterone acetate [hepatocarcinogenesis]' SubClassOf 'has role' some 'androgen antagonist' 'cyproterone acetate [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'cyproterone acetate [hepatocarcinogenesis]' SubClassOf 'chloroethene' 'cyproterone acetate [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004499 DNA damage [hepatocarcinogenesis] 'DNA damage [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'DNA damage [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'DNA damage [hepatocarcinogenesis]' SubClassOf 'has participant' some '2-acetamidofluorene [hepatocarcinogenesis]' 'DNA damage [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'DNA damage [hepatocarcinogenesis]' SubClassOf 'DNA damage' 'DNA damage [hepatocarcinogenesis]' SubClassOf 'removing damaged object' http://purl.obolibrary.org/obo/TXPO_0004494 formation of DNA adducts 'formation of DNA adducts' SubClassOf 'DNA binding' 'formation of DNA adducts' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004495 formation of DNA adducts [hepatocarcinogenesis] 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA damage [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor suppressor gene mutation [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has result' some 'proto-oncogene mutation [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has participant' some 'malondialdehyde [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'formation of DNA adducts' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has participant' some 'riddelliine [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has participant' some 'chloroethene [hepatocarcinogenesis]' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'formation of DNA adducts [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'formation of DNA adducts' http://purl.obolibrary.org/obo/TXPO_0004496 malondialdehyde [hepatocarcinogenesis] 'malondialdehyde [hepatocarcinogenesis]' SubClassOf 'malondialdehyde' 'malondialdehyde [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'malondialdehyde [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'formation of DNA adducts' 'malondialdehyde [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'formation of DNA adducts [hepatocarcinogenesis]' 'malondialdehyde [hepatocarcinogenesis]' SubClassOf 'negative regulation of signaling' http://purl.obolibrary.org/obo/TXPO_0004497 riddelliine [hepatocarcinogenesis] 'riddelliine [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'riddelliine' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'DNA alkylation' 'riddelliine [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004490 negative regulation of connexin signaling 'negative regulation of connexin signaling' SubClassOf 'negative regulation of signaling' 'negative regulation of connexin signaling' SubClassOf 'negatively regulates' some 'connexin signaling (primitive)' 'negative regulation of connexin signaling' SubClassOf 'negatively regulates' some 'Connexin signal transduction pathway' 'negative regulation of connexin signaling' SubClassOf 'decreasing quantity' 'negative regulation of connexin signaling' SubClassOf 'has input' some 'CYP1A2 (mol)' http://purl.obolibrary.org/obo/TXPO_0004491 DNA alkylation [hepatocarcinogenesis] 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'DNA alkylation' 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'chloroethene [hepatocarcinogenesis]' 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'chloroethene [hepatocarcinogenesis]' 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'negative regulation of connexin signaling' 'DNA alkylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'CYP1A2 (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004492 chloroethene [hepatocarcinogenesis] 'chloroethene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'chloroethene' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CYP1A2 (predicted)(human) [hepatocarcinogenesis]' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'has input' some '17β-Estradiol' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'PHB (human) [hepatocarcinogenesis]' 'chloroethene [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004493 Removing damaged DNA stress 'Removing damaged DNA stress' SubClassOf 'removing damaged object' 'Removing damaged DNA stress' SubClassOf 'hyperfunction of Cyp gene expression' http://purl.obolibrary.org/obo/TXPO_0004487 Hyperfunction of CYP2E1 gene expression 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'hyperfunction of Cyp gene expression' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'has output' some 'Connexin signal transduction pathway' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'Decreasing CYP1A2 level [hepatocarcinogenesis]' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'has result' some 'connexin signaling (primitive)' 'Hyperfunction of CYP2E1 gene expression' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004488 Connexin signal transduction pathway 'Connexin signal transduction pathway' SubClassOf 'signaling pathway' 'Connexin signal transduction pathway' SubClassOf 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' 'Connexin signal transduction pathway' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004489 connexin signaling (primitive) 'connexin signaling (primitive)' SubClassOf 'has pathway' some 'Connexin signal transduction pathway' 'connexin signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'connexin signaling (primitive)' SubClassOf 'JNK signaling (primitive)' 'connexin signaling (primitive)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'connexin signaling (primitive)' SubClassOf 'has result' some 'increasing production amount of reactive aldehyde [mitochondrial disorder]' 'connexin signaling (primitive)' SubClassOf 'has result' some 'Iron accumulation [mitochondrial disorder]' 'connexin signaling (primitive)' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004483 JNK signaling (primitive) [hepatocarcinogenesis] 'JNK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'JNK signaling (primitive)' 'JNK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'JNK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'JNK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'JNK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'NDUFB6 - inactive form (human)[mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004484 Decreasing CYP1A2 level 'Decreasing CYP1A2 level' SubClassOf 'has input' some 'CYP1A2 (mol)' 'Decreasing CYP1A2 level' SubClassOf 'decreasing quantity' 'Decreasing CYP1A2 level' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004485 Decreasing CYP1A2 level [hepatocarcinogenesis] 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'Decreasing CYP1A2 level' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'has input' some 'CYP1A2 (mol)' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'increasing quantity' 'Decreasing CYP1A2 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004486 Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis] 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'has input' some '17β-Estradiol' 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'Hypofunction of 17β-Estradiol metabolic process' 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004480 CXCR4 (mol) 'CXCR4 (mol)' SubClassOf 'molecule' 'CXCR4 (mol)' SubClassOf 'Increasing CXCR4 level [hepatocarcinogenesis]' 'CXCR4 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'CXCR4 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CXCR4 (mol)' SubClassOf 'has participant' some 'CXCR4 (human) [hepatocarcinogenesis]' 'CXCR4 (mol)' SubClassOf 'has pathway' some 'Decreasing CYP1A2 level' 'CXCR4 (mol)' SubClassOf 'has result' some 'JNK signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004481 Increasing CXCR4 level [hepatocarcinogenesis] 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'CXCR4 (human) [hepatocarcinogenesis]' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'JNK signaling (primitive) [hepatocarcinogenesis]' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'Increasing CXCR4 level' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CXCR3 (mol)' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'Increasing CXCR4 level [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Decreasing CYP1A2 level' http://purl.obolibrary.org/obo/TXPO_0004482 CXCR4 (human) [hepatocarcinogenesis] 'CXCR4 (human) [hepatocarcinogenesis]' SubClassOf 'CXCR4 (mol)' 'CXCR4 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'CXCR4 (human) [hepatocarcinogenesis]' SubClassOf 'CXCR3 (mol)' 'CXCR4 (human) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0000924 PLA2G2E (mol) 'PLA2G2E (mol)' SubClassOf 'group IIE secretory phospholipase A2' 'PLA2G2E (mol)' SubClassOf 'relateds assay' some 'in vitro assay' 'PLA2G2E (mol)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0000736 'PLA2G2E (mol)' SubClassOf 'has role' some 'positive regulator of immune response' 'PLA2G2E (mol)' SubClassOf 'family of' some 'PLA2 (mol)' 'PLA2G2E (mol)' SubClassOf 'has role' some 'phospholipase' 'PLA2G2E (mol)' SubClassOf 'phospholipidosis dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0000919 lipid homeostasis imbalance (mild) [Lipidosis] 'lipid homeostasis imbalance (mild) [Lipidosis]' SubClassOf 'has state' some 'toxicological imbalance SM' http://purl.obolibrary.org/obo/TXPO_0004557 Decreasing GPHN level 'Decreasing GPHN level' SubClassOf 'has input' some 'GPHN (mol)' 'Decreasing GPHN level' SubClassOf 'decreasing quantity' 'Decreasing GPHN level' SubClassOf 'has participant' some 'CYP2A13 (canonical) [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'decreasing adiponectin level [mitochondrial disorder]' 'Decreasing GPHN level' SubClassOf 'has participant' some 'aflatoxin B1 [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'has result' some 'PPARalpha activation [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'has participant' some 'aflatoxin metabolic process [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'has participant' some 'CYP1A2(canonical) [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'has pathway' some 'decreasing adiponectin level' 'Decreasing GPHN level' SubClassOf 'has participant' some 'Wnt' 'Decreasing GPHN level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing GPHN level' SubClassOf 'has participant' some 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' 'Decreasing GPHN level' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing GPHN level' SubClassOf 'has participant' some 'CYP2A6 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004558 Decreasing GPHN level [hepatocarcinogenesis] 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'has result' some 'TOR signaling (primitive)　[hepatocarcinogenesis]' 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'has input' some 'GPHN (predicted)(human) [hepatocarcinogenesis]' 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'Decreasing GPHN level' 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'has output' some ('AMPK (mol)' and ('has quality' some 'active')) 'Decreasing GPHN level [hepatocarcinogenesis]' SubClassOf 'molecular activation' http://purl.obolibrary.org/obo/TXPO_0004559 GSK3beta signal transduction pathway 'GSK3beta signal transduction pathway' SubClassOf 'signaling pathway' 'GSK3beta signal transduction pathway' SubClassOf 'mitochondrial disorder dependent process' 'GSK3beta signal transduction pathway' SubClassOf 'has result' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'GSK3beta signal transduction pathway' SubClassOf 'has output' some 'GSK3beta signal (primitive)' 'GSK3beta signal transduction pathway' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'GSK3beta signal transduction pathway' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'GSK3beta signal transduction pathway' SubClassOf 'Decreasing GPHN level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004553 Increasing GDF15 level 'Increasing GDF15 level' SubClassOf 'has output' some 'GDF15 (mol)' 'Increasing GDF15 level' SubClassOf 'increasing quantity' 'Increasing GDF15 level' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004554 Increasing GDF15 level 'Increasing GDF15 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing GDF15 level' SubClassOf 'has output' some 'GDF15(rat) [hepatocarcinogenesis]' 'Increasing GDF15 level' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'Increasing GDF15 level' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Increasing GDF15 level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing GDF15 level' SubClassOf 'Increasing GDF15 level' 'Increasing GDF15 level' SubClassOf 'has participant' some 'FGF2 (mol)' 'Increasing GDF15 level' SubClassOf 'signaling [biological] (primitive)' 'Increasing GDF15 level' SubClassOf 'has pathway' some 'Increasing GDF15 level' http://purl.obolibrary.org/obo/TXPO_0004555 GDF15(rat) [hepatocarcinogenesis] 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'GDF15 (mol)' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Increasing GDF15 level' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing GPHN level' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'Increasing GDF15 level' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'negative regulation of gap-junctional intercellular communication' 'GDF15(rat) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004556 negative regulation of gap-junctional intercellular communication 'negative regulation of gap-junctional intercellular communication' SubClassOf 'negative regulation process' 'negative regulation of gap-junctional intercellular communication' SubClassOf 'FGF2 (mol)' 'negative regulation of gap-junctional intercellular communication' SubClassOf 'PPARGC1A (mol)' 'negative regulation of gap-junctional intercellular communication' SubClassOf 'has related human gene' some 'FGF2' http://purl.obolibrary.org/obo/TXPO_0004550 Decreasing GADD45G level 'Decreasing GADD45G level' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Decreasing GADD45G level' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing GADD45G level' SubClassOf 'Decreasing GADD45G level' 'Decreasing GADD45G level' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'Decreasing GADD45G level' SubClassOf 'has participant' some 'clofibrate [hepatocarcinogenesis]' 'Decreasing GADD45G level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing GADD45G level' SubClassOf 'has input' some 'GADD45G (rat) [hepatocarcinogenesis]' 'Decreasing GADD45G level' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004551 clofibrate [hepatocarcinogenesis] 'clofibrate [hepatocarcinogenesis]' SubClassOf 'clofibrate' 'clofibrate [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'clofibrate [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'clofibrate [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'clofibrate [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'clofibrate [hepatocarcinogenesis]' SubClassOf 'has output' some 'GADD45G (rat) [hepatocarcinogenesis]' 'clofibrate [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'clofibrate [hepatocarcinogenesis]' SubClassOf 'Decreasing GADD45G level' http://purl.obolibrary.org/obo/TXPO_0004552 GADD45G (rat) [hepatocarcinogenesis] 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'GADD45G (mol)' 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'FGF21' 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'FGF21 (mol)' 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'GADD45G (rat) [hepatocarcinogenesis]' SubClassOf 'family of' some 'FGF-21' http://purl.obolibrary.org/obo/TXPO_0004546 FZD 'FZD' SubClassOf 'GPCR' 'FZD' SubClassOf 'Hypofunction of heme biosynthesis [mitochondrial disorder]' 'FZD' SubClassOf 'liver carcinogenesis dependent process' 'FZD' SubClassOf 'has participant' some 'GPCR' 'FZD' SubClassOf 'has pathway' some 'FOXO1 - activation state (canonical)[mitochondrial disorder]' 'FZD' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'FZD' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004547 GPCR 'GPCR' SubClassOf 'molecule' 'GPCR' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005130 'GPCR' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004548 Decreasing GADD45G level 'Decreasing GADD45G level' SubClassOf 'decreasing quantity' 'Decreasing GADD45G level' SubClassOf 'has input' some 'GADD45G (mol)' 'Decreasing GADD45G level' SubClassOf 'signaling [biological] (primitive)' 'Decreasing GADD45G level' SubClassOf 'has pathway' some 'Fas signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004549 GADD45G (mol) 'GADD45G (mol)' SubClassOf 'molecule' 'GADD45G (mol)' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'GADD45G (mol)' SubClassOf 'mitochondrial disorder dependent process' 'GADD45G (mol)' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'GADD45G (mol)' SubClassOf 'has participant' some 'Fas [Hepatocarcinogenesis]' 'GADD45G (mol)' SubClassOf 'Decreasing GADD45G level' 'GADD45G (mol)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'GADD45G (mol)' SubClassOf 'has pathway' some 'Fas signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004542 FOXO1 activation 'FOXO1 activation' SubClassOf 'molecular activation' 'FOXO1 activation' SubClassOf 'has output' some ('AMPK (mol)' and ('has quality' some 'active')) 'FOXO1 activation' SubClassOf 'occurs in' some 'liver' 'FOXO1 activation' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'FOXO1 activation' SubClassOf 'liver carcinogenesis dependent process' 'FOXO1 activation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FOXO1 activation' SubClassOf 'inflammatory response' http://purl.obolibrary.org/obo/TXPO_0004543 FOXO1 activation [mitochondrial disorder] 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has output' some 'FOXO1 - activation state (canonical)[mitochondrial disorder]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'Hypofunction of heme biosynthesis [mitochondrial disorder]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'FOXO1 activation' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'HNF4A (canonical) [hepatocarcinogenesis]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'Hyperfunction of DNA biosynthesis' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'increasing demand for response to oxidative stress' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'FOXO1 activation [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004544 FOXO1 - activation state (canonical)[mitochondrial disorder] 'FOXO1 - activation state (canonical)[mitochondrial disorder]' SubClassOf 'family of' some 'FOXO1 (mol)' 'FOXO1 - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has quality' some 'active' 'FOXO1 - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has role' some 'positive regulator of gluconeogenic gene transcription role' 'FOXO1 - activation state (canonical)[mitochondrial disorder]' SubClassOf 'FOXO1 (canonical)[mitochondrial disorder]' 'FOXO1 - activation state (canonical)[mitochondrial disorder]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004545 Hypofunction of heme biosynthesis [mitochondrial disorder] 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'hypofunction of heme biosynthesis' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'dysfunctioning of' some 'heme biosynthetic process' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'signaling [biological] (primitive)' 'Hypofunction of heme biosynthesis [mitochondrial disorder]' SubClassOf 'has pathway' some 'FOXO1 - activation state (canonical)[mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004540 increasing FGF21 level [mitochondrial disorder] 'increasing FGF21 level [mitochondrial disorder]' SubClassOf 'has output' some 'FGF21(canonical) [mitochondrial disorder]' 'increasing FGF21 level [mitochondrial disorder]' SubClassOf 'increasing FGF21 level' 'increasing FGF21 level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing FGF21 level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing FGF21 level [mitochondrial disorder]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004541 FGF21(canonical) [mitochondrial disorder] 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'FGF21 (mol)' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'family of' some 'FGF-21' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has related human gene' some 'FGF21' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'FOXO1 activation [mitochondrial disorder]' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing ACSL4 level' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'increasing demand for response to ER stress' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'FOXO1 activation' 'FGF21(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004539 increasing FGF21 level 'increasing FGF21 level' SubClassOf 'increasing quantity' 'increasing FGF21 level' SubClassOf 'has participant' some 'BIP (mol)' 'increasing FGF21 level' SubClassOf 'has pathway' some 'increasing FGF21 level [mitochondrial disorder]' 'increasing FGF21 level' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004535 FAK signaling (primitive) [hepatocarcinogenesis] 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'FAK signaling (primitive)' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'FAK signal transduction pathway' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'FAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'FAK signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004536 Fas signaling pathway [mitochondrial disorder] 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'Fas signaling pathway' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'has result' some 'FAS signaling [mitochondrial disorder]' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'has participant' some 'FAS signaling (primitive)' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'has pathway' some 'FAK signaling (primitive)' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Fas signaling pathway [mitochondrial disorder]' SubClassOf 'FAK signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004537 FAS signaling (primitive) 'FAS signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'FAS signaling (primitive)' SubClassOf 'has pathway' some 'Fas signaling pathway' 'FAS signaling (primitive)' SubClassOf 'Perfluorooctanoic acid' 'FAS signaling (primitive)' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004538 FAS signaling [mitochondrial disorder] 'FAS signaling [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has pathway' some 'Fas signaling pathway' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'FAS signaling [mitochondrial disorder]' SubClassOf 'FAS signaling (primitive)' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'FAS signaling [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'FAS signaling [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FAS signaling [mitochondrial disorder]' SubClassOf 'hepatic cirrhosis [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004531 inflammatory response [hepatocarcinogenesis] 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'inflammatory response' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'increasing demand for response to ER stress [hepatocarcinogenesis]' 'inflammatory response [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004532 increasing demand for response to oxidative stress [hepatocarcinogenesis] 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'increasing demand for response to oxidative stress' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA damage [hepatocarcinogenesis]' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'inflammatory response [hepatocarcinogenesis]' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'increasing demand for response to ER stress [hepatocarcinogenesis]' 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' SubClassOf 'negative regulation of signaling' http://purl.obolibrary.org/obo/TXPO_0004533 FAK signal transduction pathway 'FAK signal transduction pathway' SubClassOf 'signaling pathway' 'FAK signal transduction pathway' SubClassOf 'USP7 (mol)' 'FAK signal transduction pathway' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005128 http://purl.obolibrary.org/obo/TXPO_0004534 FAK signaling (primitive) 'FAK signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'FAK signaling (primitive)' SubClassOf 'has pathway' some 'FAK signal transduction pathway' 'FAK signaling (primitive)' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004530 increasing demand for response to ER stress [hepatocarcinogenesis] 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'increasing demand for response to ER stress' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'inflammatory response [hepatocarcinogenesis]' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'increasing demand for response to ER stress [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004528 Grp78 signal (primitive) 'Grp78 signal (primitive)' SubClassOf 'has pathway' some 'Grp78 signal transduction pathway' 'Grp78 signal (primitive)' SubClassOf 'signaling [biological] (primitive)' 'Grp78 signal (primitive)' SubClassOf 'has participant' some 'BIP (mol)' 'Grp78 signal (primitive)' SubClassOf 'EGFR (mol)' 'Grp78 signal (primitive)' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Grp78 signal (primitive)' SubClassOf 'family of' some 'EGFR (mol)' http://purl.obolibrary.org/obo/TXPO_0004529 Grp78 signal transduction pathway 'Grp78 signal transduction pathway' SubClassOf 'signaling pathway' 'Grp78 signal transduction pathway' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Grp78 signal transduction pathway' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'Grp78 signal transduction pathway' SubClassOf 'liver carcinogenesis dependent process' 'Grp78 signal transduction pathway' SubClassOf 'tumor malignancy alteration [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004524 ERK signaling (primitive) 'ERK signaling (primitive)' SubClassOf 'has pathway' some 'ERK signal transduction pathway' 'ERK signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'ERK signaling (primitive)' SubClassOf 'has output' some 'DPYD (mol)' 'ERK signaling (primitive)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004525 ERK signaling (primitive) [hepatocarcinogenesis] 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'ERK signal transduction pathway' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'pentadecafluorooctanoic acid' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Metalloprotease activation [hepatocarcinogenesis]' 'ERK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has output' some 'DPYD (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004526 pentadecafluorooctanoic acid 'pentadecafluorooctanoic acid' SubClassOf 'Perfluorooctanoic acid' 'pentadecafluorooctanoic acid' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'pentadecafluorooctanoic acid' SubClassOf 'liver carcinogenesis dependent process' 'pentadecafluorooctanoic acid' SubClassOf 'has result' some 'Grp78 signal transduction pathway' 'pentadecafluorooctanoic acid' SubClassOf 'has participant' some 'Grp78 signal (primitive)' 'pentadecafluorooctanoic acid' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'pentadecafluorooctanoic acid' SubClassOf 'EGFR signaling (primitive)' 'pentadecafluorooctanoic acid' SubClassOf 'has participant' some 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' 'pentadecafluorooctanoic acid' SubClassOf 'has pathway' some 'epidermal growth factor receptor signaling pathway' 'pentadecafluorooctanoic acid' SubClassOf 'has result' some 'ACSL1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004527 negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis] 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'negative regulation of gap-junctional intercellular communication' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'EGFR (mol)' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'family of' some 'EGFR (mol)' 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004520 EPCR signal transduction pathway 'EPCR signal transduction pathway' SubClassOf 'signaling pathway' 'EPCR signal transduction pathway' SubClassOf 'increasing quantity' 'EPCR signal transduction pathway' SubClassOf 'has output' some 'EPCR signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004521 EPCR signaling (primitive) 'EPCR signaling (primitive)' SubClassOf 'has pathway' some 'EPCR signal transduction pathway' 'EPCR signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'EPCR signaling (primitive)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004522 negative regulation of EPCR signaling 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'EPCR signaling (primitive)' 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'EPCR signal transduction pathway' 'negative regulation of EPCR signaling' SubClassOf 'negative regulation of signaling' 'negative regulation of EPCR signaling' SubClassOf 'EPCR signal transduction pathway' 'negative regulation of EPCR signaling' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of EPCR signaling' SubClassOf 'has output' some 'ERK signal transduction pathway' 'negative regulation of EPCR signaling' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of EPCR signaling' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004523 ERK signal transduction pathway 'ERK signal transduction pathway' SubClassOf 'signaling pathway' 'ERK signal transduction pathway' SubClassOf 'USP7 (mol)' 'ERK signal transduction pathway' SubClassOf 'EPCR signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004597 HNF4A (mol) 'HNF4A (mol)' SubClassOf 'molecule' 'HNF4A (mol)' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'HNF4A (mol)' SubClassOf 'PPARalpha activation' 'HNF4A (mol)' SubClassOf 'has output' some 'SFRP1 inactivation' 'HNF4A (mol)' SubClassOf 'liver carcinogenesis dependent process' 'HNF4A (mol)' SubClassOf 'has result' some 'STAT3 activation [hepatocarcinogenesis]' 'HNF4A (mol)' SubClassOf 'has participant' some 'HBEGF (rat) [hepatocarcinogenesis]' 'HNF4A (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004598 HNF4A - inactive form (canonical) [hepatocarcinogenesis] 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'HNF4A (canonical) [hepatocarcinogenesis]' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'HULC' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has part' some 'Increasing HULC level' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'HULC (human) [hepatocarcinogenesis]' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Increasing HULC level [hepatocarcinogenesis]' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0048012 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004599 HULC 'HULC' SubClassOf 'ncRNA gene of Homo sapiens' 'HULC' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0048012 'HULC' SubClassOf 'has participant' some 'Hedgehog signal transduction pathway' 'HULC' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004593 Increasing iron uptake level [hepatocarcinogenesis] 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'has result' some 'iron metabolic dysfunction [hepatocarcinogenesis]' 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'Increasing iron uptake level' 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'increasing production amount of reactive aldehyde' 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'STK3 (mol)' 'Increasing iron uptake level [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004594 Increasing HMGB1 level 'Increasing HMGB1 level' SubClassOf 'increasing quantity' 'Increasing HMGB1 level' SubClassOf 'has output' some 'HMGB1 (mol)' 'Increasing HMGB1 level' SubClassOf 'occurs in' some 'liver' 'Increasing HMGB1 level' SubClassOf 'pathogen proliferation' http://purl.obolibrary.org/obo/TXPO_0004595 HMGB1 (canonical) [mitochondrial disorder] 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'HMGB1 (mol)' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Decreasing GPHN level' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'HNF4A inactivation' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'HNF4A (mol)' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'Increasing HMGB1 level' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'CCND1 (human) [hepatocarcinogenesis]' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'GDF15(rat) [hepatocarcinogenesis]' 'HMGB1 (canonical) [mitochondrial disorder]' SubClassOf 'occurs in' some 'liver' http://purl.obolibrary.org/obo/TXPO_0004596 HNF4A inactivation 'HNF4A inactivation' SubClassOf 'inactivation' 'HNF4A inactivation' SubClassOf 'has output' some ('HNF4A (mol)' and ('has quality' some 'inactive')) 'HNF4A inactivation' SubClassOf 'has output' some 'NRF2 inactivation [mitochondrial disorder]' 'HNF4A inactivation' SubClassOf 'has output' some 'NRF2 - inactive form (canonical) [mitochondrial disorder]' 'HNF4A inactivation' SubClassOf 'has result' some 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' 'HNF4A inactivation' SubClassOf 'liver carcinogenesis dependent process' 'HNF4A inactivation' SubClassOf 'NRF2 inactivation' 'HNF4A inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004590 HIF1A - activation state (canonical)[mitochondrial disorder] 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'HIF1A(canonical) [mitochondrial disorder]' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has quality' some 'active' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'malfunctioning of centrosome duplication' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has input' some 'HIF1A(canonical) [hepatocarcinogenesis]' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'HIF1A - activation state (canonical)[mitochondrial disorder]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004591 Increasing HILPDA level 'Increasing HILPDA level' SubClassOf 'increasing quantity' 'Increasing HILPDA level' SubClassOf 'has output' some 'HILPDA (mol)' 'Increasing HILPDA level' SubClassOf 'has participant' some 'increasing production amount of reactive aldehyde' 'Increasing HILPDA level' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' 'Increasing HILPDA level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing HILPDA level' SubClassOf 'necrosis' 'Increasing HILPDA level' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Increasing HILPDA level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004592 Increasing HILPDA level [hepatocarcinogenesis] 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing iron uptake level [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has output' some 'HILPDA (predicted)(human) [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'Increasing HILPDA level' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has part' some 'COX-2 (canonical) [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'has part' some 'FZD9 (canonical) [hepatocarcinogenesis]' 'Increasing HILPDA level [hepatocarcinogenesis]' SubClassOf 'CDT1 (human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004586 HHIP - inactive form (human) [hepatocarcinogenesis] 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'HHIP (human) [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PIM3 activation' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PIM3 activation [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'PIM3 (human) [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Notch signaling pathway' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PI3K signaling (primitive) [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'HHIP - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'PI3K signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004587 trimeric UHRF1 repression complex (human) [hepatocarcinogenesis] 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has component' some 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has component' some 'DNMT1 (human) [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'trimeric UHRF1 repression complex' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has component' some 'USP7 (human) [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'negative regulation of TSLC signaling [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL1 level' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'negative regulation of TSLC signaling' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'CADM1 (rat) [hepatocarcinogenesis]' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' SubClassOf 'has part' some 'TAZ (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004588 HIF1A activation 'HIF1A activation' SubClassOf 'has output' some ('HIF1A (mol)' and ('has quality' some 'active')) 'HIF1A activation' SubClassOf 'molecular activation' 'HIF1A activation' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'HIF1A activation' SubClassOf 'TGF beta receptor signaling (primitive)' 'HIF1A activation' SubClassOf 'liver carcinogenesis dependent process' 'HIF1A activation' SubClassOf 'has result' some 'APC signal transduction pathway' 'HIF1A activation' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'HIF1A activation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HIF1A activation' SubClassOf 'has result' some 'FZD9 (canonical) [hepatocarcinogenesis]' 'HIF1A activation' SubClassOf 'has participant' some 'FZD7 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004589 HIF1A (mol) 'HIF1A (mol)' SubClassOf 'molecule' 'HIF1A (mol)' SubClassOf 'has pathway' some 'TSLC signal transduction pathway' 'HIF1A (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HIF1A (mol)' SubClassOf 'has result' some 'APC signal transduction pathway' 'HIF1A (mol)' SubClassOf 'has participant' some 'alcohol [hepatocarcinogenesis]' 'HIF1A (mol)' SubClassOf 'alcohol intake [hepatocarcinogenesis]' 'HIF1A (mol)' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004582 HGF (rat) [hepatocarcinogenesis] 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'has output' some 'HHIP inactivation' 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'HGF (rat) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004583 HHIP inactivation 'HHIP inactivation' SubClassOf 'inactivation' 'HHIP inactivation' SubClassOf 'has output' some ('HHIP (mol)' and ('has quality' some 'inactive')) 'HHIP inactivation' SubClassOf 'USP7 (mol)' 'HHIP inactivation' SubClassOf 'Increasing HGF level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004584 HHIP (mol) 'HHIP (mol)' SubClassOf 'molecule' 'HHIP (mol)' SubClassOf 'pathogen proliferation' 'HHIP (mol)' SubClassOf 'occurs in' some 'liver' http://purl.obolibrary.org/obo/TXPO_0004585 HHIP inactivation [hepatocarcinogenesis] 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'HHIP inactivation' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has agent' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'HHIP - inactive form (human) [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'FGF21(canonical) [mitochondrial disorder]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'HIF1A (mol)' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'HHIP - inactive form (human) [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'HHIP (mol)' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'HIF1A activation' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'CCND1 (human) [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing iron uptake level [hepatocarcinogenesis]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'HIF1A - activation state (canonical)[mitochondrial disorder]' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing HILPDA level' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing GPHN level' 'HHIP inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing HILPDA level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004580 HGF (mol) 'HGF (mol)' SubClassOf 'molecule' 'HGF (mol)' SubClassOf 'increasing quantity' 'HGF (mol)' SubClassOf 'has output' some 'Increasing HGF level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004581 Increasing HGF level [hepatocarcinogenesis] 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'has output' some 'HGF (rat) [hepatocarcinogenesis]' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'Increasing HGF level' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'Increasing HGF level [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004579 Increasing HGF level 'Increasing HGF level' SubClassOf 'has output' some 'HGF (mol)' 'Increasing HGF level' SubClassOf 'increasing quantity' 'Increasing HGF level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing HGF level' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'Increasing HGF level' SubClassOf 'MTAP (human) [hepatocarcinogenesis]' 'Increasing HGF level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004575 HCV infection [hepatocarcinogenesis] 'HCV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'WNT signaling (primitive) [hepatocarcinogenesis]' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'PPARalpha activation [hepatocarcinogenesis]' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing MIR135A level [hepatocarcinogenesis]' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'HCV infection' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'hepatic cirrhosis [hepatocarcinogenesis]' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'HCV infection [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004576 Increasing MIR135A level [hepatocarcinogenesis] 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'Increasing MIR135A level' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'has result' some 'PTPRD inactivation [hepatocarcinogenesis]' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'has output' some 'MIR135A1 (human) [hepatocarcinogenesis]' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'has output' some 'MIR135A2 (human) [hepatocarcinogenesis]' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'HCV infection [hepatocarcinogenesis]' 'Increasing MIR135A level [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004577 PPARalpha activation [hepatocarcinogenesis] 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has output' some 'PPARA - activation state (mouse) [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'lipid storage in liver [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'clofibrate [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'PPARalpha activation' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'CCND1 (human) [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'aristolochic acid [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Decreasing arachidonic acid level' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Notch signaling [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'positive regulation of arachidonic acid metabolic process' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'FAS signaling [mitochondrial disorder]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'tumor cell survial [hepatocarcinogenesis]' 'PPARalpha activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004578 WNT signaling (primitive) [hepatocarcinogenesis] 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD2 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD9 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'WNT signaling (primitive)' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD6 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Wnt' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD1 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'WNT signal transduction pathway' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD7 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD5 (canonical) [hepatocarcinogenesis]' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has role' some 'chaperone role' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'BIP (mol)' 'WNT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'ER stress dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0004571 necrosis [hepatocarcinogenesis] 'necrosis [hepatocarcinogenesis]' SubClassOf 'necrosis' 'necrosis [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'necrosis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Methapyrilene hydrochloride [hepatocarcinogenesis]' 'necrosis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'necrosis [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor suppressor gene mutation [hepatocarcinogenesis]' 'necrosis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'necrosis [hepatocarcinogenesis]' SubClassOf 'GDF15 (mol)' 'necrosis [hepatocarcinogenesis]' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004572 hepatic cirrhosis [hepatocarcinogenesis] 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'hepatic cirrhosis' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'has result' some 'inflammatory response [hepatocarcinogenesis]' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL4 [hepatocarcinogenesis]' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'hepatic cirrhosis [hepatocarcinogenesis]' SubClassOf 'negative regulation process' http://purl.obolibrary.org/obo/TXPO_0004573 hepatocyte regeneration [hepatocarcinogenesis] 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor suppressor gene mutation [hepatocarcinogenesis]' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf '肝細胞再生' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Methapyrilene hydrochloride [hepatocarcinogenesis]' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'has input' some 'GPHN (mol)' 'hepatocyte regeneration [hepatocarcinogenesis]' SubClassOf 'decreasing quantity' http://purl.obolibrary.org/obo/TXPO_0004574 HCV infection 'HCV infection' SubClassOf 'pathogen proliferation' 'HCV infection' SubClassOf 'occurs in' some 'liver' 'HCV infection' SubClassOf 'hepatocyte regeneration [hepatocarcinogenesis]' 'HCV infection' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HCV infection' SubClassOf 'has input' some 'GPHN (predicted)(human) [hepatocarcinogenesis]' 'HCV infection' SubClassOf 'has result' some 'p38 signaling (primitive) [hepatocarcinogenesis]' 'HCV infection' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004570 telomerase reverse transcriptase gene mutation [hepatocarcinogenesis] 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'Telomerase reverse transcriptase gene mutation' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'TERT (canonical) [hepatocarcinogenesis]' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'has output' some 'necrosis [hepatocarcinogenesis]' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'HBV infection [hepatocarcinogenesis]' 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004568 HBV infection 'HBV infection' SubClassOf 'occurs in' some 'liver' 'HBV infection' SubClassOf 'pathogen proliferation' 'HBV infection' SubClassOf 'HBEGF (mol)' 'HBV infection' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004569 HBV infection [hepatocarcinogenesis] 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'telomerase reverse transcriptase gene mutation [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'necrosis [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of DNA repair [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'hepatic cirrhosis [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor suppressor gene mutation [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'hepatocyte regeneration [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has result' some 'increasing demand for response to ER stress [hepatocarcinogenesis]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'HBV infection' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'has output' some 'GDF15 (mol)' 'HBV infection [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004564 Increasing HBEGF level 'Increasing HBEGF level' SubClassOf 'has output' some 'HBEGF (mol)' 'Increasing HBEGF level' SubClassOf 'increasing quantity' 'Increasing HBEGF level' SubClassOf 'decreasing quantity' 'Increasing HBEGF level' SubClassOf 'has input' some 'HBEGF (mol)' http://purl.obolibrary.org/obo/TXPO_0004566 Increasing HBEGF level [hepatocarcinogenesis] 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has output' some 'HBEGF (rat) [hepatocarcinogenesis]' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has input' some 'HBV infection' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'HBEGF (rat) [hepatocarcinogenesis]' 'Increasing HBEGF level [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004567 HBEGF (rat) [hepatocarcinogenesis] 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf 'HBEGF (mol)' 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'HBEGF (rat) [hepatocarcinogenesis]' SubClassOf 'clofibrate' http://purl.obolibrary.org/obo/TXPO_0004560 GSK3beta signal (primitive) 'GSK3beta signal (primitive)' SubClassOf 'signaling [biological] (primitive)' 'GSK3beta signal (primitive)' SubClassOf 'has pathway' some 'GSK3beta signal transduction pathway' 'GSK3beta signal (primitive)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005080 'GSK3beta signal (primitive)' SubClassOf 'family of' some 'FOXO1 (mol)' 'GSK3beta signal (primitive)' SubClassOf 'has role' some 'positive regulator of gluconeogenic gene transcription role' 'GSK3beta signal (primitive)' SubClassOf 'has quality' some 'active' http://purl.obolibrary.org/obo/TXPO_0004561 beta-catenin signaling (primitive) [hepatocarcinogenesis] 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'beta-catenin signal (primitive)' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'hepatic cirrhosis [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'MMP7 signaling (primitive) [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Ctnnb1 (canonical) [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hepatic fibrosis [hepatocarcinogenesis]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'NDUFV3 (human) [mitochondrial disorder]' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'dysfunctioning of' some 'heme biosynthetic process' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004562 GRP78 (canonical)[hepatocarcinogenesis] 'GRP78 (canonical)[hepatocarcinogenesis]' SubClassOf 'ER stress dependent molecule (canonical)' 'GRP78 (canonical)[hepatocarcinogenesis]' SubClassOf 'has role' some 'chaperone role' 'GRP78 (canonical)[hepatocarcinogenesis]' SubClassOf 'BIP (mol)' 'GRP78 (canonical)[hepatocarcinogenesis]' SubClassOf 'cisplatin resistance [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004563 cisplatin resistance [hepatocarcinogenesis] 'cisplatin resistance [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'cisplatin resistance [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'cisplatin resistance [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'cisplatin resistance [hepatocarcinogenesis]' SubClassOf 'cisplatin resistance' 'cisplatin resistance [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004517 EGFR(canonical) [hepatocarcinogenesis] 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'family of' some 'EGFR (mol)' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'EGFR (mol)' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'DNA replication' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'manifests phenotype' some 'number of objects' 'EGFR(canonical) [hepatocarcinogenesis]' SubClassOf 'has agent' some 'sorafenib resistance (process) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004518 EGFR(human) [hepatocarcinogenesis] 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'EGFR (mol)' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'family of' some 'EGFR (mol)' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'tumor cell proliferation' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'macrophage migration [mitochondrial disorder]' 'EGFR(human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004519 sorafenib resistance (process) [hepatocarcinogenesis] 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'sorafenib resistance (process)' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'FEN1' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'sorafenib resistance (process) [hepatocarcinogenesis]' SubClassOf 'FEN1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004513 DNMT1 (rat) [hepatocarcinogenesis] 'DNMT1 (rat) [hepatocarcinogenesis]' SubClassOf 'DNMT1 (mol)' 'DNMT1 (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'DNMT1 (rat) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'DNMT1 (rat) [hepatocarcinogenesis]' SubClassOf '2-acetamidofluorene' http://purl.obolibrary.org/obo/TXPO_0004514 Increasing DPYD level 'Increasing DPYD level' SubClassOf 'has output' some 'DPYD (mol)' 'Increasing DPYD level' SubClassOf 'increasing quantity' 'Increasing DPYD level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing DPYD level' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'Increasing DPYD level' SubClassOf 'hyperfunction of' some 'DNA biosynthetic process' 'Increasing DPYD level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing DPYD level' SubClassOf 'Increasing DPYD level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004515 Increasing DPYD level [hepatocarcinogenesis] 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'has result' some 'p38 signaling (primitive) [hepatocarcinogenesis]' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'Increasing DPYD level' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'has output' some 'DPYD (predicted)(human) [hepatocarcinogenesis]' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'hyperfunction of biosynthesis' 'Increasing DPYD level [hepatocarcinogenesis]' SubClassOf 'hyperfunction of' some 'DNA biosynthetic process' http://purl.obolibrary.org/obo/TXPO_0004516 EGFR signaling (primitive) [hepatocarcinogenesis] 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'sorafenib resistance (process) [hepatocarcinogenesis]' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'EGFR(canonical) [hepatocarcinogenesis]' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'epidermal growth factor receptor signaling pathway' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'EGFR signaling (primitive)' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'EGFR(human) [hepatocarcinogenesis]' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'fumonisin B1' 'EGFR signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004510 Increasing DNMT1 level 'Increasing DNMT1 level' SubClassOf 'increasing quantity' 'Increasing DNMT1 level' SubClassOf 'has output' some 'DNMT1 (mol)' 'Increasing DNMT1 level' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005099 'Increasing DNMT1 level' SubClassOf 'has quality' some 'inactive' 'Increasing DNMT1 level' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004511 DNMT1 (mol) 'DNMT1 (mol)' SubClassOf 'molecule' 'DNMT1 (mol)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005101 'DNMT1 (mol)' SubClassOf 'has quality' some 'inactive' 'DNMT1 (mol)' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004512 Increasing DNMT1 level [hepatocarcinogenesis] 'Increasing DNMT1 level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'Increasing DNMT1 level [hepatocarcinogenesis]' SubClassOf 'Increasing DNMT1 level' 'Increasing DNMT1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'DNMT1 (rat) [hepatocarcinogenesis]' 'Increasing DNMT1 level [hepatocarcinogenesis]' SubClassOf 'mitochondrial respiratory chain complex I subunit phosphorylation' 'Increasing DNMT1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004506 fumonisin B1 [hepatocarcinogenesis] 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'fumonisin B1' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has input' some 'Decreasing glucose level [mitochondrial disorder]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'increasing glucose level' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has participant' some 'increasing glucose level [mitochondrial disorder]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has input' some 'Decreasing arachidonic acid level' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has participant' some 'decreasing glucose level' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has participant' some 'ORC1 - inactive form (human) [hepatocarcinogenesis]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has input' some 'Negative regulation of glutathione transport' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PANDA' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has input' some 'hyperfunction of gluconeogenesis' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'fumonisin B1 [hepatocarcinogenesis]' SubClassOf 'has input' some 'decreasing glutathione level' http://purl.obolibrary.org/obo/TXPO_0004507 DNA replication [hepatocarcinogenesis] 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has agent' some 'FEN1 (human) [hepatocarcinogenesis]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'manifests phenotype' some 'number of objects' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'DNA replication' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has input' some 'NDUFS2 inactivation [mitochondrial disorder]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'GJB1 (human) [hepatocarcinogenesis]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Increasing cholesterol level [mitochondrial disorder]' 'DNA replication [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004508 Tumor cell proliferation [Hepatocarcinogenesis] 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'has participant' some 'BECN1 (human) [hepatocarcinogenesis]' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'tumor cell proliferation' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'negative regulation of DNA repair' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'has participant' some 'DNMT1 (mol)' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'has participant' some 'FEN1 (human) [hepatocarcinogenesis]' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'DNA repair' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'has participant' some 'Increasing DNMT1 level' 'Tumor cell proliferation [Hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing DNMT1 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004509 FEN1 (human) [hepatocarcinogenesis] 'FEN1 (human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'FEN1' 'FEN1 (human) [hepatocarcinogenesis]' SubClassOf 'FEN1 (mol)' 'FEN1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'FEN1 (human) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005092 'FEN1 (human) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004502 negative regulation of DNA repair [hepatocarcinogenesis] 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'negative regulation of DNA repair' 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'DNA repair' 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'negative regulation of DNA repair [hepatocarcinogenesis]' SubClassOf 'malondialdehyde' http://purl.obolibrary.org/obo/TXPO_0004503 2-acetamidofluorene [hepatocarcinogenesis] '2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf '2-acetamidofluorene' '2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'riddelliine' '2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004504 Hyperfunction of DNA biosynthesis [hepatocarcinogenesis] 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'hyperfunction of' some 'DNA biosynthetic process' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'Hyperfunction of DNA biosynthesis' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'cyproterone acetate' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' SubClassOf 'has role' some 'androgen antagonist' http://purl.obolibrary.org/obo/TXPO_0004505 Hyperfunction of DNA biosynthesis 'Hyperfunction of DNA biosynthesis' SubClassOf 'hyperfunction of biosynthesis' 'Hyperfunction of DNA biosynthesis' SubClassOf 'hyperfunction of' some 'DNA biosynthetic process' 'Hyperfunction of DNA biosynthesis' SubClassOf 'liver carcinogenesis dependent process' 'Hyperfunction of DNA biosynthesis' SubClassOf 'DNA damage' 'Hyperfunction of DNA biosynthesis' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Hyperfunction of DNA biosynthesis' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hyperfunction of DNA biosynthesis' SubClassOf 'has participant' some 'DNMT1 (rat) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004500 proto-oncogene mutation [hepatocarcinogenesis] 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'HRAS (mouse) [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'KRAS (mouse) [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some '4-(phenylazo)aniline [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'NRAS (mouse) [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'proto-oncogene mutation' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'chloroethene [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some '7,12-dimethyltetraphene [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'Ctnnb1 (canonical) [hepatocarcinogenesis]' 'proto-oncogene mutation [hepatocarcinogenesis]' SubClassOf 'DNA binding' http://purl.obolibrary.org/obo/TXPO_0004501 tumor suppressor gene mutation [hepatocarcinogenesis] 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'Tumor suppressor gene mutation' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has input' some 'TP53(canonical) [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'aflatoxin B1 [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some '2-acetamidofluorene [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hyperfunction of DNA biosynthesis' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has result' some 'fumonisin B1 [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'negative regulation of DNA repair [hepatocarcinogenesis]' 'tumor suppressor gene mutation [hepatocarcinogenesis]' SubClassOf 'proto-oncogene mutation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004678 NDUFA12 (mol) 'NDUFA12 (mol)' SubClassOf 'molecule' 'NDUFA12 (mol)' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'NDUFA12 (mol)' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'NDUFA12 (mol)' SubClassOf 'has quality' some 'predicted (quality)' 'NDUFA12 (mol)' SubClassOf 'has related human gene' some 'KIAA0101' http://purl.obolibrary.org/obo/TXPO_0004679 NDUFB6 inactivation 'NDUFB6 inactivation' SubClassOf 'inactivation' 'NDUFB6 inactivation' SubClassOf 'has output' some ('NDUFB6 (mol)' and ('has quality' some 'inactive')) 'NDUFB6 inactivation' SubClassOf 'negative regulation of autophagy' 'NDUFB6 inactivation' SubClassOf 'liver carcinogenesis dependent process' 'NDUFB6 inactivation' SubClassOf 'has result' some 'TERT (canonical) [hepatocarcinogenesis]' 'NDUFB6 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004674 Myc(mouse) [hepatocarcinogenesis] 'Myc(mouse) [hepatocarcinogenesis]' SubClassOf 'Myc (mol)' 'Myc(mouse) [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'Myc(mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'Myc(mouse) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'Myc(mouse) [hepatocarcinogenesis]' SubClassOf 'dichloroacetic acid' http://purl.obolibrary.org/obo/TXPO_0004675 N-nitrosodiethylamine [hepatocarcinogenesis] 'N-nitrosodiethylamine [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'N-nitrosodiethylamine [hepatocarcinogenesis]' SubClassOf 'N-nitrosodiethylamine' 'N-nitrosodiethylamine [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'N-nitrosodiethylamine [hepatocarcinogenesis]' SubClassOf 'trichloroethylene' http://purl.obolibrary.org/obo/TXPO_0004676 N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis] 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'N-hydroxy-2-acetamidofluorene' 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' SubClassOf 'trichloroacetic acid' http://purl.obolibrary.org/obo/TXPO_0004677 NDUFA12 inactivation 'NDUFA12 inactivation' SubClassOf 'has output' some ('NDUFA12 (mol)' and ('has quality' some 'inactive')) 'NDUFA12 inactivation' SubClassOf 'has output' some ('KIAA0101 (mol)' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004670 PMID:30141584 Increasing MYC level [hepatocarcinogenesis] 'PMID:30141584' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'PMID:30141584' SubClassOf 'liver carcinogenesis dependent process' 'PMID:30141584' SubClassOf 'has output' some 'Myc(rat) [hepatocarcinogenesis]' 'PMID:30141584' SubClassOf 'Increasing MYC level' 'PMID:30141584' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'PMID:30141584' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PMID:30141584' SubClassOf 'JUN (mol)' 'PMID:30141584' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004671 Myc(rat) [hepatocarcinogenesis] 'Myc(rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'Myc(rat) [hepatocarcinogenesis]' SubClassOf 'family of' some 'Myc (mol)' 'Myc(rat) [hepatocarcinogenesis]' SubClassOf 'Myc (mol)' 'Myc(rat) [hepatocarcinogenesis]' SubClassOf 'MYC gene promoter demethylation' http://purl.obolibrary.org/obo/TXPO_0004672 MYC gene promoter demethylation 'MYC gene promoter demethylation' SubClassOf 'proto-oncogene promoter demethylation' 'MYC gene promoter demethylation' SubClassOf 'demethylation' http://purl.obolibrary.org/obo/TXPO_0004673 MYC gene promoter demethylation [hepatocarcinogenesis] 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'Myc(mouse) [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'MYC gene promoter demethylation' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'Myc(rat) [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'trichloroethylene [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'trichloroacetic acid [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'dichloroacetic acid [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'PMID:30141584' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing MYC level' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'Myc(rat) [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Myc(mouse) [hepatocarcinogenesis]' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'PMID:30141584' 'MYC gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004667 MMP7 signaling (primitive) [hepatocarcinogenesis] 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'MMP7 signal (primitive)' 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'MMP7 signal transduction pathway' 'MMP7 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004668 MMP7 signal (primitive) 'MMP7 signal (primitive)' SubClassOf 'signaling [biological] (primitive)' 'MMP7 signal (primitive)' SubClassOf 'has pathway' some 'MMP7 signal transduction pathway' 'MMP7 signal (primitive)' SubClassOf 'increasing quantity' 'MMP7 signal (primitive)' SubClassOf 'has output' some 'JUN (mol)' http://purl.obolibrary.org/obo/TXPO_0004669 Increasing MYC level 'Increasing MYC level' SubClassOf 'has output' some 'Myc (mol)' 'Increasing MYC level' SubClassOf 'increasing quantity' 'Increasing MYC level' SubClassOf 'has output' some 'PMID:30141584' 'Increasing MYC level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing MYC level' SubClassOf 'MMP7 signal (primitive)' 'Increasing MYC level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing MYC level' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004663 MIR135A1 (human) [hepatocarcinogenesis] 'MIR135A1 (human) [hepatocarcinogenesis]' SubClassOf 'MIR135A1' 'MIR135A1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'MIR135A1 (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Increasing MIR135A level' 'MIR135A1 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CXCL10 (mol)' 'MIR135A1 (human) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004664 MIR135A2 (human) [hepatocarcinogenesis] 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'MIR135A2' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'CXCR4 (mol)' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'MIR135A1 (human) [hepatocarcinogenesis]' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Increasing MIR135A level' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Grp78 signaling (primitive) [hepatocarcinogenesis]' 'MIR135A2 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PTPRD inactivation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004665 PTPRD inactivation [hepatocarcinogenesis] 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'PTPRD inactivation' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'STAT3 activation [hepatocarcinogenesis]' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'participates in' some 'inflammatory response' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'CXCL10 (mol)' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'relateds assay' some 'in vitro assay' 'PTPRD inactivation [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004660 LDLRAD4 gene promoter methylation 'LDLRAD4 gene promoter methylation' SubClassOf 'DNA methylation' 'LDLRAD4 gene promoter methylation' SubClassOf 'IL-6 (mol)' 'LDLRAD4 gene promoter methylation' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004661 LDLRAD4 gene promoter methylation [hepatocarcinogenesis] 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'LDLRAD4 gene promoter methylation' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'LDLRAD4 (rat) [hepatocarcinogenesis]' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL4 [hepatocarcinogenesis]' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'iron atom' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'iron accumulation' 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'FOXO1 activation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004662 Increasing MIR135A level 'Increasing MIR135A level' SubClassOf 'increasing quantity' 'Increasing MIR135A level' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004656 LDLRAD4 (mol) 'LDLRAD4 (mol)' SubClassOf 'molecule' 'LDLRAD4 (mol)' SubClassOf 'has result' some 'Tumor-associated macrophage activation@hepatocarcinogenesis' 'LDLRAD4 (mol)' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0070498 'LDLRAD4 (mol)' SubClassOf 'has result' some 'Increasing CXCR4 level' 'LDLRAD4 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'LDLRAD4 (mol)' SubClassOf 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' 'LDLRAD4 (mol)' SubClassOf 'has participant' some 'LDLRAD4 (rat) [hepatocarcinogenesis]' 'LDLRAD4 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004657 Decreasing LDLRAD4 level [hepatocarcinogenesis] 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'Decreasing LDLRAD4 level' 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'has input' some 'LDLRAD4 (rat) [hepatocarcinogenesis]' 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0070498 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004658 LDLRAD4 (rat) [hepatocarcinogenesis] 'LDLRAD4 (rat) [hepatocarcinogenesis]' SubClassOf 'LDLRAD4 (mol)' 'LDLRAD4 (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'LDLRAD4 (rat) [hepatocarcinogenesis]' SubClassOf 'IL-1b (mol)' 'LDLRAD4 (rat) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'LDLRAD4 (rat) [hepatocarcinogenesis]' SubClassOf 'has role' some 'inflammatory substance role' http://purl.obolibrary.org/obo/TXPO_0004659 TGF beta receptor signaling (primitive) [hepatocarcinogenesis] 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'TGF beta receptor signaling (primitive)' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'interleukin-6-mediated signaling pathway' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor-associated macrophage activation@hepatocarcinogenesis' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'IL-6 signaling (primitive)' 'TGF beta receptor signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'LDLRAD4 gene promoter methylation' http://purl.obolibrary.org/obo/TXPO_0004652 Increasing KIAA0101 tv1 level [hepatocarcinogenesis] 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'Increasing KIAA0101 level' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'NDUFB6 inactivation' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'NDUFA12 (mol)' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of autophagy [hepatocarcinogenesis]' 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' SubClassOf 'NDUFA12 inactivation' http://purl.obolibrary.org/obo/TXPO_0004653 KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis] 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'KIAA0101' 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004654 negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis] 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'negative regulation of p53 signaling' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' SubClassOf 'IL-6 (mol)' http://purl.obolibrary.org/obo/TXPO_0004655 Decreasing LDLRAD4 level 'Decreasing LDLRAD4 level' SubClassOf 'decreasing quantity' 'Decreasing LDLRAD4 level' SubClassOf 'has input' some 'LDLRAD4 (mol)' 'Decreasing LDLRAD4 level' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing LDLRAD4 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing LDLRAD4 level' SubClassOf 'has result' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'Decreasing LDLRAD4 level' SubClassOf 'MMP7 signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004650 negative regulation of autophagy [hepatocarcinogenesis] 'negative regulation of autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell survial [hepatocarcinogenesis]' 'negative regulation of autophagy [hepatocarcinogenesis]' SubClassOf 'negative regulation of autophagy' 'negative regulation of autophagy [hepatocarcinogenesis]' SubClassOf 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'negative regulation of autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing KIAA0101 tv1 level [hepatocarcinogenesis]' 'negative regulation of autophagy [hepatocarcinogenesis]' SubClassOf 'has output' some 'Increasing KIAA0101 level' http://purl.obolibrary.org/obo/TXPO_0004651 Increasing KIAA0101 level 'Increasing KIAA0101 level' SubClassOf 'increasing quantity' 'Increasing KIAA0101 level' SubClassOf 'has output' some 'KIAA0101 (mol)' 'Increasing KIAA0101 level' SubClassOf 'has quality' some 'inactive' 'Increasing KIAA0101 level' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'Increasing KIAA0101 level' SubClassOf 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' 'Increasing KIAA0101 level' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004649 KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis] 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'KIAA0101' 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has output' some ('IL-6 (mol)' and ('has quality' some 'inactive')) 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004645 dichloroacetic acid [hepatocarcinogenesis] 'dichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'dichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'dichloroacetic acid' 'dichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004646 trichloroethylene [hepatocarcinogenesis] 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'trichloroethylene' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'JUN gene promoter demethylation [hepatocarcinogenesis]' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'has agent' some 'Hippo signal transduction pathway' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'trichloroethylene [hepatocarcinogenesis]' SubClassOf 'has output' some 'trichloroacetic acid [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004647 trichloroacetic acid [hepatocarcinogenesis] 'trichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'trichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'trichloroacetic acid' 'trichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'trichloroacetic acid [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005095 'trichloroacetic acid [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004648 KIAA0101 inactivation 'KIAA0101 inactivation' SubClassOf 'inactivation' 'KIAA0101 inactivation' SubClassOf 'has output' some ('KIAA0101 (mol)' and ('has quality' some 'inactive')) 'KIAA0101 inactivation' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'KIAA0101 inactivation' SubClassOf 'IL-1b (mol)' 'KIAA0101 inactivation' SubClassOf 'has role' some 'inflammatory substance role' http://purl.obolibrary.org/obo/TXPO_0004641 JUN(mouse) [hepatocarcinogenesis] 'JUN(mouse) [hepatocarcinogenesis]' SubClassOf 'JUN (mol)' 'JUN(mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'JUN(mouse) [hepatocarcinogenesis]' SubClassOf 'has output' some 'UHRF1 (mol)' 'JUN(mouse) [hepatocarcinogenesis]' SubClassOf 'protein production' http://purl.obolibrary.org/obo/TXPO_0004642 JUN gene promoter demethylation 'JUN gene promoter demethylation' SubClassOf 'proto-oncogene promoter demethylation' 'JUN gene promoter demethylation' SubClassOf 'has output' some ('IFN alpha' and ('has quality' some 'inactive')) 'JUN gene promoter demethylation' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004643 proto-oncogene promoter demethylation 'proto-oncogene promoter demethylation' SubClassOf 'demethylation' 'proto-oncogene promoter demethylation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'proto-oncogene promoter demethylation' SubClassOf 'has result' some 'ERK signaling (primitive) [hepatocarcinogenesis]' 'proto-oncogene promoter demethylation' SubClassOf 'liver carcinogenesis dependent process' 'proto-oncogene promoter demethylation' SubClassOf 'has output' some ('IFN alpha' and ('has quality' some 'inactive')) 'proto-oncogene promoter demethylation' SubClassOf 'JUN gene promoter demethylation' http://purl.obolibrary.org/obo/TXPO_0004644 JUN gene promoter demethylation [hepatocarcinogenesis] 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'trichloroethylene [hepatocarcinogenesis]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'dichloroacetic acid [hepatocarcinogenesis]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'trichloroacetic acid [hepatocarcinogenesis]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'JUN gene promoter demethylation' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'JUN(mouse) [hepatocarcinogenesis]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing JUN level [hepatocarcinogenesis]' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'inactivation' 'JUN gene promoter demethylation [hepatocarcinogenesis]' SubClassOf 'has output' some ('dichloroacetic acid [hepatocarcinogenesis]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004640 Increasing JUN level [hepatocarcinogenesis] 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has output' some 'JUN(mouse) [hepatocarcinogenesis]' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'Increasing JUN level' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 inactivation' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'CYP3A5(canonical) [hepatocarcinogenesis]' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CYP3A7 (canonical) [hepatocarcinogenesis]' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Grp78 signal transduction pathway' 'Increasing JUN level [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'CYP3A4(canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0003388 phospholipid transport from lysosome into cytosol 'phospholipid transport from lysosome into cytosol' SubClassOf 'phospholipid transport to membrane' 'phospholipid transport from lysosome into cytosol' SubClassOf 'phospholipid transport' http://purl.obolibrary.org/obo/TXPO_0003372 phospholipid metabolism imbalance [Phospholipidosis (moderate) ] 'phospholipid metabolism imbalance [Phospholipidosis (moderate) ]' SubClassOf 'has state' some 'toxicological imbalance LVL' 'phospholipid metabolism imbalance [Phospholipidosis (moderate) ]' SubClassOf 'has state' some 'toxicological imbalance ML' http://purl.obolibrary.org/obo/TXPO_0003370 phospholipid homeostasis imbalance [Phospholipidosis (moderate) ] 'phospholipid homeostasis imbalance [Phospholipidosis (moderate) ]' SubClassOf 'has state' some 'toxicological imbalance ML' http://purl.obolibrary.org/obo/TXPO_0004696 Notch signaling (primitive) 'Notch signaling (primitive)' SubClassOf 'has pathway' some 'Notch signaling pathway' 'Notch signaling (primitive)' SubClassOf 'has pathway' some 'hypofunction of lipid biosynthesis [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004697 Notch 1 (canonical) [hepatocarcinogenesis] 'Notch 1 (canonical) [hepatocarcinogenesis]' SubClassOf 'Notch 1 (mol)' 'Notch 1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'Notch 1 (canonical) [hepatocarcinogenesis]' SubClassOf 'increasing quantity' 'Notch 1 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'Myc (mol)' http://purl.obolibrary.org/obo/TXPO_0004698 Notch 2 (canonical) [hepatocarcinogenesis] 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'Notch 2 (mol)' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'ORC1 inactivation' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'UHRF1 production [hepatocarcinogenesis]' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'Notch 1 (canonical) [hepatocarcinogenesis]' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'Notch 3 (canonical) [hepatocarcinogenesis]' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Notch 2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004699 Notch 3 (canonical) [hepatocarcinogenesis] 'Notch 3 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'Notch 3 (canonical) [hepatocarcinogenesis]' SubClassOf 'Notch 3 (mol)' 'Notch 3 (canonical) [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'Notch 3 (canonical) [hepatocarcinogenesis]' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'Notch 3 (canonical) [hepatocarcinogenesis]' SubClassOf 'Myc (mol)' http://purl.obolibrary.org/obo/TXPO_0004692 NRF2 - inactive form (canonical) [mitochondrial disorder] 'NRF2 - inactive form (canonical) [mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NRF2 - inactive form (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'NRF2 - inactive form (canonical) [mitochondrial disorder]' SubClassOf 'NRF2(canonical) [mitochondrial disorder]' 'NRF2 - inactive form (canonical) [mitochondrial disorder]' SubClassOf 'MIR135A2' 'NRF2 - inactive form (canonical) [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004693 negative regulation of antioxidant enzyme activation [mitochondrial disorder] 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of anti-oxidative stress[mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'negative regulation of antioxidant enzyme activation' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'TAZ (mol)' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'has output' some 'TAZ signaling (primitive) [hepatocarcinogenesis]' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' SubClassOf 'has result' some 'TAZ (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004694 hypofunction of lipid biosynthesis [mitochondrial disorder] 'hypofunction of lipid biosynthesis [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'hypofunction of lipid biosynthesis [mitochondrial disorder]' SubClassOf 'hypofunction of lipid biosynthesis' 'hypofunction of lipid biosynthesis [mitochondrial disorder]' SubClassOf 'dysfunctioning of' some 'lipid biosynthetic process' 'hypofunction of lipid biosynthesis [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'hypofunction of lipid biosynthesis [mitochondrial disorder]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004695 Notch signaling [hepatocarcinogenesis] 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Notch 3 (canonical) [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Notch 1 (canonical) [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 production [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Notch 2 (canonical) [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Notch signaling pathway' 'Notch signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' http://purl.obolibrary.org/obo/TXPO_0004690 NRF2 inactivation 'NRF2 inactivation' SubClassOf 'inactivation' 'NRF2 inactivation' SubClassOf 'has output' some ('NRF2 (mol)' and ('has quality' some 'inactive')) 'NRF2 inactivation' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004691 NRF2 inactivation [mitochondrial disorder] 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of lipid biosynthesis [mitochondrial disorder]' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'NRF2 inactivation' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of mitochondrial fatty acid beta-oxidation [Mitochondrial disorder]' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NRF2 - inactive form (canonical) [mitochondrial disorder]' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'MIR135A1' 'NRF2 inactivation [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004689 increasing production quantity of RNS [mitochondrial disorder] 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has result' some 'DNA damage [Mitochondrial disorder]' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'increasing production quantity of RNS' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'Increasing production quantity of NO [mitochondrial disorder]' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has input' some 'Increasing production quantity of NO' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has result' some 'NDUFV3 (mol)' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'increasing production quantity of RNS [mitochondrial disorder]' SubClassOf 'has participant' some 'positive regulation of cell cycle [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0003354 transportng lysosomal enzyme from to lysosome [Phospholipidosis] 'transportng lysosomal enzyme from to lysosome [Phospholipidosis]' SubClassOf 'occurs in' some 'late endosome' http://purl.obolibrary.org/obo/TXPO_0004685 NDUFV3 inactivation 'NDUFV3 inactivation' SubClassOf 'has output' some ('NDUFV3 (mol)' and ('has quality' some 'inactive')) 'NDUFV3 inactivation' SubClassOf 'inactivation' 'NDUFV3 inactivation' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0003355 transportng lysosomal enzyme from ribosome to lysosome 'transportng lysosomal enzyme from ribosome to lysosome' SubClassOf 'has target start location' some 'lysosome' 'transportng lysosomal enzyme from ribosome to lysosome' SubClassOf 'has target end location' some 'ribosome' 'transportng lysosomal enzyme from ribosome to lysosome' SubClassOf 'has target end location' some 'lysosome' 'transportng lysosomal enzyme from ribosome to lysosome' SubClassOf 'has target start location' some 'ribosome' 'transportng lysosomal enzyme from ribosome to lysosome' SubClassOf 'occurs in' some 'late endosome' http://purl.obolibrary.org/obo/TXPO_0004686 NDUFV3 (mol) 'NDUFV3 (mol)' SubClassOf 'molecule' 'NDUFV3 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'NDUFV3 (mol)' SubClassOf 'has input' some 'Increasing production quantity of NO' 'NDUFV3 (mol)' SubClassOf 'NDUFV1 (mol)' 'NDUFV3 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'NDUFV3 (mol)' SubClassOf 'has result' some 'HIF1A activation' http://purl.obolibrary.org/obo/TXPO_0004687 Increasing production quantity of NO 'Increasing production quantity of NO' SubClassOf 'increasing quantity' 'Increasing production quantity of NO' SubClassOf 'NDUFV3 inactivation' 'Increasing production quantity of NO' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004688 Increasing production quantity of NO [mitochondrial disorder] 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'Increasing production quantity of NO' 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'has result' some 'increasing production quantity of RNS [mitochondrial disorder]' 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing production quantity of NO [mitochondrial disorder]' SubClassOf 'DNA methylation' http://purl.obolibrary.org/obo/TXPO_0004681 NDUFS2 inactivaiton 'NDUFS2 inactivaiton' SubClassOf 'has output' some ('NDUFS2 (mol)' and ('has quality' some 'inactive')) 'NDUFS2 inactivaiton' SubClassOf 'inactivation' 'NDUFS2 inactivaiton' SubClassOf 'has output' some 'NDUFS2 (mol)' 'NDUFS2 inactivaiton' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'NDUFS2 inactivaiton' SubClassOf 'liver carcinogenesis dependent process' 'NDUFS2 inactivaiton' SubClassOf 'has result' some 'IP-10 signaling (primitive)' 'NDUFS2 inactivaiton' SubClassOf 'has result' some 'ACSL4 (mol)' 'NDUFS2 inactivaiton' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'NDUFS2 inactivaiton' SubClassOf 'NDUFB6 (mol)' 'NDUFS2 inactivaiton' SubClassOf 'has result' some 'NDUFV1 inactivation' 'NDUFS2 inactivaiton' SubClassOf 'has result' some 'Increasing CXCR4 level' http://purl.obolibrary.org/obo/TXPO_0004682 NDUFS2 (mol) 'NDUFS2 (mol)' SubClassOf 'molecule' 'NDUFS2 (mol)' SubClassOf 'has related human gene' some 'KIAA0101' 'NDUFS2 (mol)' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'NDUFS2 (mol)' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'NDUFS2 (mol)' SubClassOf 'has quality' some 'predicted (quality)' http://purl.obolibrary.org/obo/TXPO_0004683 NDUFV1 inactivation 'NDUFV1 inactivation' SubClassOf 'has output' some ('NDUFV1 (mol)' and ('has quality' some 'inactive')) 'NDUFV1 inactivation' SubClassOf 'inactivation' 'NDUFV1 inactivation' SubClassOf 'has part' some 'TLR4 (canonical) [mitochondrial disorder]' 'NDUFV1 inactivation' SubClassOf 'has participant' some 'glucose homeostasis imbalance [mitochondrial disorder]' 'NDUFV1 inactivation' SubClassOf 'has result' some 'ACSL1 (mol)' 'NDUFV1 inactivation' SubClassOf 'negative regulation of p53 signaling' 'NDUFV1 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'NDUFV1 inactivation' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004684 NDUFV1 (mol) 'NDUFV1 (mol)' SubClassOf 'molecule' 'NDUFV1 (mol)' SubClassOf 'decreasing quantity' 'NDUFV1 (mol)' SubClassOf 'has input' some 'NDUFV3 inactivation' http://purl.obolibrary.org/obo/TXPO_0004680 NDUFB6 (mol) 'NDUFB6 (mol)' SubClassOf 'molecule' 'NDUFB6 (mol)' SubClassOf 'has output' some 'KIAA0101 (mol)' 'NDUFB6 (mol)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004638 STAT3 signaling (primitive) [hepatocarcinogenesis] 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Snail1 signaling [hepatocarcinogenesis]' 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'STAT3(human) [hepatocarcinogenesis]' 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'STAT3 signaling (primitive)' 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005093 'STAT3 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004639 Increasing JUN level 'Increasing JUN level' SubClassOf 'increasing quantity' 'Increasing JUN level' SubClassOf 'has output' some 'JUN (mol)' 'Increasing JUN level' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005094 'Increasing JUN level' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004634 IP-10 signaling (primitive) [hepatocarcinogenesis] 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'CXCR3 signaling [hepatocarcinogenesis]' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'IP-10 signaling (primitive)' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'IP-10 signal transduction pathway' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CXCL10 (canonical) [hepatocarcinogenesis]' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'glycolytic process' 'IP-10 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004635 CXCL10 (canonical) [hepatocarcinogenesis] 'CXCL10 (canonical) [hepatocarcinogenesis]' SubClassOf 'participates in' some 'inflammatory response' 'CXCL10 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CXCL10 (canonical) [hepatocarcinogenesis]' SubClassOf 'CXCL10 (mol)' 'CXCL10 (canonical) [hepatocarcinogenesis]' SubClassOf 'relateds assay' some 'in vitro assay' 'CXCL10 (canonical) [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004636 JAK signal transduction pathway 'JAK signal transduction pathway' SubClassOf 'signaling pathway' 'JAK signal transduction pathway' SubClassOf 'liver carcinogenesis dependent process' 'JAK signal transduction pathway' SubClassOf 'has participant' some 'Increasing JUN level' 'JAK signal transduction pathway' SubClassOf 'JAK signaling (primitive)' 'JAK signal transduction pathway' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'JAK signal transduction pathway' SubClassOf 'has pathway' some 'CXCL10 (canonical) [hepatocarcinogenesis]' 'JAK signal transduction pathway' SubClassOf 'has result' some 'Increasing JUN level [hepatocarcinogenesis]' 'JAK signal transduction pathway' SubClassOf 'has participant' some 'STAT3 signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004637 JAK signaling (primitive) 'JAK signaling (primitive)' SubClassOf 'has pathway' some 'JAK signal transduction pathway' 'JAK signaling (primitive)' SubClassOf 'has participant' some http://purl.obolibrary.org/obo/TXPO_0005094 'JAK signaling (primitive)' SubClassOf 'has participant' some http://purl.obolibrary.org/obo/TXPO_0005093 'JAK signaling (primitive)' SubClassOf 'has pathway' some 'CXCL10 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004630 IL-6(human)[hepatocarcinogenesis] 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'IL-6 (mol)' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has result' some 'FZD' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'Increasing IL-6 level' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has result' some 'IP-10 signaling (primitive)' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has pathway' some 'KIAA0101 inactivation [hepatocarcinogenesis]' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has result' some 'IP-10 signaling (primitive) [hepatocarcinogenesis]' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has participant' some 'JAK signaling (primitive) [hepatocarcinogenesis]' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IL-6(human)[hepatocarcinogenesis]' SubClassOf 'has participant' some 'IP-10 signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004631 JAK signaling (primitive) [hepatocarcinogenesis] 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'JAK signaling (primitive)' 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'STAT3 signaling (primitive) [hepatocarcinogenesis]' 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'IHH (mol)' 'JAK signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004632 IP-10 signal transduction pathway 'IP-10 signal transduction pathway' SubClassOf 'signaling pathway' 'IP-10 signal transduction pathway' SubClassOf 'PPARGC1A (mol)' 'IP-10 signal transduction pathway' SubClassOf 'SHH (mol)' http://purl.obolibrary.org/obo/TXPO_0004633 IP-10 signaling (primitive) 'IP-10 signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'IP-10 signaling (primitive)' SubClassOf 'has pathway' some 'IP-10 signal transduction pathway' 'IP-10 signaling (primitive)' SubClassOf 'has participant' some 'CXCL10 (mol)' 'IP-10 signaling (primitive)' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'IP-10 signaling (primitive)' SubClassOf 'liver carcinogenesis dependent process' 'IP-10 signaling (primitive)' SubClassOf 'Cell Transformation, Neoplastic' 'IP-10 signaling (primitive)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004627 IL-6 - inactive form (human)[hepatocarcinogenesis] 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'IL-6(human)[hepatocarcinogenesis]' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has output' some 'increasing production quantity of ROS [hepatocarcinogenesis]' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'Decreasing MIR150 level [hepatocarcinogenesis]' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IL-6 - inactive form (human)[hepatocarcinogenesis]' SubClassOf 'has output' some 'hypofunction of S-adenosylmethionine biosynthetic process' http://purl.obolibrary.org/obo/TXPO_0004628 KIAA0101 inactivation [hepatocarcinogenesis] 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'KIAA0101 inactivation' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'KIAA0101 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of autophagy [hepatocarcinogenesis]' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'IL-6 inactivation [hepatocarcinogenesis]' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'KIAA0101 inactivation [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004629 Increasing IL-6 level 'Increasing IL-6 level' SubClassOf 'increasing quantity' 'Increasing IL-6 level' SubClassOf 'has output' some 'IL-6(human)[hepatocarcinogenesis]' 'Increasing IL-6 level' SubClassOf 'signaling [biological] (primitive)' 'Increasing IL-6 level' SubClassOf 'has pathway' some 'KIAA0101 inactivation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004623 IGFBP3 - inactive form (human) [hepatocarcinogenesis] 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'IGFBP3 (human) [hepatocarcinogenesis]' 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'ncRNA gene of Homo sapiens' http://purl.obolibrary.org/obo/TXPO_0004624 IL-1B(canonical) [mitochondrial disorder] 'IL-1B(canonical) [mitochondrial disorder]' SubClassOf 'IL-1b (mol)' 'IL-1B(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'IL-1B(canonical) [mitochondrial disorder]' SubClassOf 'has role' some 'inflammatory substance role' 'IL-1B(canonical) [mitochondrial disorder]' SubClassOf 'has output' some 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' 'IL-1B(canonical) [mitochondrial disorder]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004625 IL-6 inactivation 'IL-6 inactivation' SubClassOf 'has output' some ('IL-6 (mol)' and ('has quality' some 'inactive')) 'IL-6 inactivation' SubClassOf 'inactivation' 'IL-6 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IL-6 inactivation' SubClassOf 'IL-1B(canonical) [mitochondrial disorder]' 'IL-6 inactivation' SubClassOf 'liver carcinogenesis dependent process' 'IL-6 inactivation' SubClassOf 'has output' some 'IL-6 inactivation [hepatocarcinogenesis]' 'IL-6 inactivation' SubClassOf 'has result' some 'IL-6 - inactive form (human)[hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004626 IL-6 inactivation [hepatocarcinogenesis] 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'KIAA0101 inactivation [hepatocarcinogenesis]' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'IL-6 inactivation' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'IL-6 - inactive form (human)[hepatocarcinogenesis]' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IL-6 inactivation [hepatocarcinogenesis]' SubClassOf 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004622 IGFBP3 inactivation [hepatocarcinogenesis] 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'IGFBP3 inactivation' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'has agent' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'IGFBP3 - inactive form (human) [hepatocarcinogenesis]' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'IGFBP3 inactivation [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005091 http://purl.obolibrary.org/obo/TXPO_0004616 YAP signaling (primitive) [hepatocarcinogenesis] 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'YAP signaling (primitive)' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'sorafenib resistance (process) [hepatocarcinogenesis]' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'YAP1 (canonical) [hepatocarcinogenesis]' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'TAZ signaling (primitive) [hepatocarcinogenesis]' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'YAP signal transduction pathway' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'STK3 (canonical) [hepatocarcinogenesis]' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 production' 'YAP signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has output' some 'HILPDA (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004617 UHRF1 production 'UHRF1 production' SubClassOf 'protein production' 'UHRF1 production' SubClassOf 'has output' some 'UHRF1 (mol)' 'UHRF1 production' SubClassOf 'NDUFV1 inactivation [mitochondrial disorder]' 'UHRF1 production' SubClassOf 'has result' some 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' 'UHRF1 production' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'UHRF1 production' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004618 IFN alpha inactivation 'IFN alpha inactivation' SubClassOf 'has output' some ('IFN alpha' and ('has quality' some 'inactive')) 'IFN alpha inactivation' SubClassOf 'inactivation' 'IFN alpha inactivation' SubClassOf 'increasing quantity' 'IFN alpha inactivation' SubClassOf 'has output' some 'HMGB1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004619 IFN alpha inactivation [hepatocarcinogenesis] 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing DPYD level [hepatocarcinogenesis]' 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'IFN alpha inactivation' 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some ('IFN alpha' and ('has quality' some 'inactive')) 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'IFN alpha inactivation [hepatocarcinogenesis]' SubClassOf 'HMGB1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004612 Hippo signaling (primitive) [hepatocarcinogenesis] 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'YAP signaling (primitive) [hepatocarcinogenesis]' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'MST1 (canonical) [hepatocarcinogenesis]' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'Hippo signaling (primitive)' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Hippo signal transduction pathway' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'STK3 (canonical) [hepatocarcinogenesis]' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'molecular activation' 'Hippo signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has output' some ('Hippo signaling (primitive)' and ('has quality' some 'active')) http://purl.obolibrary.org/obo/TXPO_0004613 Hippo signaling (primitive) 'Hippo signaling (primitive)' SubClassOf 'has participant' some 'MST1 (mol)' 'Hippo signaling (primitive)' SubClassOf 'has participant' some 'STK3 (mol)' 'Hippo signaling (primitive)' SubClassOf 'has pathway' some 'Hippo signal transduction pathway' 'Hippo signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'Hippo signaling (primitive)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004614 MST1 (canonical) [hepatocarcinogenesis] 'MST1 (canonical) [hepatocarcinogenesis]' SubClassOf 'MST1 (mol)' 'MST1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'MST1 (canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005090 'MST1 (canonical) [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'MST1 (canonical) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'active' http://purl.obolibrary.org/obo/TXPO_0004615 STK3 (canonical) [hepatocarcinogenesis] 'STK3 (canonical) [hepatocarcinogenesis]' SubClassOf 'STK3 (mol)' 'STK3 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'STK3 (canonical) [hepatocarcinogenesis]' SubClassOf 'increasing quantity' 'STK3 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'HILPDA (mol)' http://purl.obolibrary.org/obo/TXPO_0004610 glycolytic process [hepatocarcinogenesis] 'glycolytic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'glycolytic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'glycolytic process [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'glycolytic process [hepatocarcinogenesis]' SubClassOf 'glycolytic process' 'glycolytic process [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005089 'glycolytic process [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004611 Hippo signal transduction pathway 'Hippo signal transduction pathway' SubClassOf 'signaling pathway' 'Hippo signal transduction pathway' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Hippo signal transduction pathway' SubClassOf '4-(phenylazo)aniline [hepatocarcinogenesis]' 'Hippo signal transduction pathway' SubClassOf 'has role' some 'transcription regulator' 'Hippo signal transduction pathway' SubClassOf 'has component' some 'HRAS (mouse) [hepatocarcinogenesis]' 'Hippo signal transduction pathway' SubClassOf 'has component' some 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'Hippo signal transduction pathway' SubClassOf 'has component' some 'KRAS (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004609 Cell Transformation, Neoplastic [hepatocarcinogenesis] 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'Cell Transformation, Neoplastic' 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'has output' some 'glycolytic process [hepatocarcinogenesis]' 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'IHH (canonical) [hepatocarcinogenesis]' 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' SubClassOf 'has agent' some 'Hippo signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004605 Hedgehog signaling (primitive) 'Hedgehog signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'Hedgehog signaling (primitive)' SubClassOf 'has pathway' some 'Hedgehog signal transduction pathway' 'Hedgehog signaling (primitive)' SubClassOf 'has output' some 'Hedgehog signal transduction pathway' 'Hedgehog signaling (primitive)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004606 Hedgehog signaling [hepatocarcinogenesis] 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Hedgehog signal transduction pathway' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'SHH (canonical) [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'FAK signaling (primitive) [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'glycolytic process [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'Hedgehog signaling (primitive)' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'IHH (canonical) [hepatocarcinogenesis]' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'Hedgehog signal transduction pathway' 'Hedgehog signaling [hepatocarcinogenesis]' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004607 IHH (canonical) [hepatocarcinogenesis] 'IHH (canonical) [hepatocarcinogenesis]' SubClassOf 'IHH (mol)' 'IHH (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'IHH (canonical) [hepatocarcinogenesis]' SubClassOf 'inactivation' 'IHH (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some ('SHH (canonical) [hepatocarcinogenesis]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004608 SHH (canonical) [hepatocarcinogenesis] 'SHH (canonical) [hepatocarcinogenesis]' SubClassOf 'SHH (mol)' 'SHH (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'SHH (canonical) [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004601 Increasing HULC level [hepatocarcinogenesis] 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'Increasing HULC level' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'has output' some 'HULC (human) [hepatocarcinogenesis]' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'Hedgehog signal transduction pathway' 'Increasing HULC level [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004602 HULC (human) [hepatocarcinogenesis] 'HULC (human) [hepatocarcinogenesis]' SubClassOf 'HULC' 'HULC (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'HULC (human) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005098 'HULC (human) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004603 Increasing PPARA level [hepatocarcinogenesis] 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'Increasing PPARA level' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL1 level [hepatocarcinogenesis]' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PPARA(canonical) [hepatocarcinogenesis]' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'biological structure formation' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'NDUFS2 (human) [mitochondrial disorder]' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'Increasing PPARA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004604 Hedgehog signal transduction pathway 'Hedgehog signal transduction pathway' SubClassOf 'signaling pathway' 'Hedgehog signal transduction pathway' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004600 Increasing HULC level 'Increasing HULC level' SubClassOf 'has output' some 'HULC' 'Increasing HULC level' SubClassOf 'increasing quantity' 'Increasing HULC level' SubClassOf 'has result' some 'EGFR(canonical) [hepatocarcinogenesis]' 'Increasing HULC level' SubClassOf 'Hedgehog signaling (primitive)' 'Increasing HULC level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing HULC level' SubClassOf 'has participant' some 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' 'Increasing HULC level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing HULC level' SubClassOf 'has output' some 'Hedgehog signaling [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004278 lipoperoxidation [mitochondrial disorder] 'lipoperoxidation [mitochondrial disorder]' SubClassOf 'has result' some 'increasing production amount of reactive aldehyde [mitochondrial disorder]' 'lipoperoxidation [mitochondrial disorder]' SubClassOf 'has result' some 'Snail1 signaling [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004276 Tumor-associated macrophage activation@hepatocarcinogenesis 'Tumor-associated macrophage activation@hepatocarcinogenesis' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Tumor-associated macrophage activation@hepatocarcinogenesis' SubClassOf 'has agent' some 'CCL2(human)[hepatocarcinogenesis]' 'Tumor-associated macrophage activation@hepatocarcinogenesis' SubClassOf 'has result' some 'increasing production amount of reactive aldehyde [mitochondrial disorder]' 'Tumor-associated macrophage activation@hepatocarcinogenesis' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004270 inflammatory cytokine gene expression [mitochondrial disorder] 'inflammatory cytokine gene expression [mitochondrial disorder]' SubClassOf 'has part' some 'inflammatory cytokine gene expression [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004271 Inflammatory response [mitochondrial disorder] 'Inflammatory response [mitochondrial disorder]' SubClassOf 'has result' some 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' 'Inflammatory response [mitochondrial disorder]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004260 decreasing mtDNA level [mitochondrial disorder] 'decreasing mtDNA level [mitochondrial disorder]' SubClassOf 'has participant' some 'didanosine [mitochondrial disorder]' 'decreasing mtDNA level [mitochondrial disorder]' SubClassOf 'has participant' some 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004256 interleukin-6 production [mitochondrial disorder] 'interleukin-6 production [mitochondrial disorder]' SubClassOf 'has output' some 'didanosine [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004253 TLR9 signaling [Mitochondrial disorder] 'TLR9 signaling [Mitochondrial disorder]' SubClassOf 'has pathway' some 'TLR9 signaling pathway [Mitochondrial disorder]' 'TLR9 signaling [Mitochondrial disorder]' SubClassOf 'has pathway' some 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004298 NfkB signaling (primitive) [hepatocarcinogenesis] 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has agent' some 'NF-kappaB' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Snail1 signaling [hepatocarcinogenesis]' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'NF-kappaB' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL1 level' 'NfkB signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Iron accumulation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004299 TLR9 signaling [hepatocarcinogenesis] 'TLR9 signaling [hepatocarcinogenesis]' SubClassOf 'has agent' some 'TLR9 (mol)' 'TLR9 signaling [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TLR9 signaling pathway [hepatocarcinogenesis]' 'TLR9 signaling [hepatocarcinogenesis]' SubClassOf 'has agent' some 'TLR9(human)[hepatocarcinogenesis]' 'TLR9 signaling [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004280 hepatocarcinogenesis [toxic course] 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CAR activation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing LDLRAD4 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PMAIP1 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PIM3 activation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'MMP7 signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hypofunction of 17β-Estradiol metabolic process [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing ACSL1 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'iron metabolic dysfunction [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'hepatocyte regeneration [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'metastasis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'cisplatin resistance [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing BCL-2 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'positive regulation of cell division [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing ACSL4 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing GDF15 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing DPYD level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'UHRF1 production [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing HGF level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'proto-oncogene mutation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'liver malfunction [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'induction of genomic instability [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing MIR150 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing CYP1A2 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing SPTLC3 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'hypoxia [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IL-6 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing CXCR4 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing demand for response to ER stress [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'glycolytic process [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'hepatic cirrhosis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PI3K signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'changing abnormal cellular structure [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Snail1 signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'GSK3beta signal (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PCNA level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'necrosis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of ROS formation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HNF4A inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Removing damaged DNA stress [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'KIAA0101 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'WNT signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TAZ signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing production quantity of ROS [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'tumor cell survial [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'lipoperoxidation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing GADD45G level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PROC gene promoter methylation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'tumorigenesis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PVT1 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HCV infection [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing lipid [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hedgehog signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'aflatoxin metabolic process [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IFN alpha inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of connexin signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of TSLC signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ATF4 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'sorafenib resistance (process) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing HULC level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HBV infection [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PTPRD inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IGFBP3 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'UHRF1 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing VEGF level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of DNA repair [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'DNA damage [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hippo signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PCK1 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PMID:30141584' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of APC signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PTPRD gene promoter methylation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'JAK signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PANDA level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing GPHN level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'STAT3 signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'JUN gene promoter demethylation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'positive regulation of arachidonic acid metabolic process' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'alcohol intake [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'formation of DNA adducts [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PHB inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing MIR135A level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of cellular senescence [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CDT1 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CXCR3 signaling [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hepatic fibrosis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FAK signaling (primitive) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'neovascularization [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'nodule formation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'inflammatory response [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'tumor malignancy alteration [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'SFRP1 inactivation [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'response to hypoxia [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PROM1 level [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hyperfunction of DNA biosynthesis [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PTPRD inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FOXO1 activation [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'BECN1 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CAR (mouse) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HMGB1 (canonical) [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PIM3 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HGF (rat) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing HILPDA level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing LDLRAD4 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing GPHN level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FAS signaling [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HCV infection' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hypofunction of TFAM gene expression' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Negative regulation of ATP transport [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HIF1A activation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'hypofunction of heme biosynthesis' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'MIR135A2 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of AKT signaling [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing CXCR4 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IL-6 - inactive form (human)[hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FZD9 (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CDH1 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'GDF15(rat) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'connexin signaling (primitive)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing MYC level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing AGGF1 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'mitochondrial membrane morphology changes' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of activation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NDUFB6 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FZD2 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Fas signaling pathway [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing ACSL4 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'STAT3(human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'fumonisin B1 [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HHIP - inactive form (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FOXO1 activation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ACSL1 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing leptin level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'MST1 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NOS2 (canonical) [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CXCR4 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'COX-2 (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hyperfunction of CYP2E1 gene expression' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CCND1 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FZD' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'pyrethrins [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing triol level [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'JAK signal transduction pathway' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HNF4A inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FGF21(canonical) [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ACSL4 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'cardiolipin peroxidation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing DPYD level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TNF signaling [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some '1-hydroxyanthraquinone' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'EGFR(canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PROM1 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NDUFS2 inactivaiton' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TGF-alpha signaling (primitive)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NDUFV3 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'UHRF1 production' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PROX1 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NDUFV1 - inactive form (human)[mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TAZ signal transduction pathway' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'metalloprotease activation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IGFBP3 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ATF4 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CXCR3(canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing HGF level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'EGFR(human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IL-6(human)[hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'LDLRAD4 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Hyperfunction of DNA biosynthesis' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IL-6 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'FZD5 (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Decreasing miR-150 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CADM1 (rat) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing production amount of reactive aldehyde [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'SPTLC3 (mouse) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing HULC level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Iron accumulation [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ATF4(human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'riddelliine [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'proto-oncogene promoter demethylation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TERT (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'chloroethene [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'aristolochic acid [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'C9ORF72 inactivation [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Pvt1 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'NDUFV1 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'cancer stem-like cell proliferation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'mitochondria morphology change' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HNF4A (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'GJB1 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'PMAIP1 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HIF1A (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing ACSL1 level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'increasing production quantity of RNS [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CPT1(canonical) [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TLR4 (canonical) [mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CDT1 - inactive form (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'pentadecafluorooctanoic acid' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'OR3A4 (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Increasing PPARA level' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HNF4A (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'UHRF1 inactivation' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'induction of genomic instability' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'ATF4 - inactive form (human) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'negative regulation of EPCR signaling' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TGF-alpha signal transduction pathway' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'TAZ (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'IP-10 signaling (primitive)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'trichloroethylene [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'nagative regulation of mitophagy' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'APC signal transduction pathway' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'CYP3A7 (mol)' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'HIF1A - activation state (canonical)[mitochondrial disorder]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Notch 2 (canonical) [hepatocarcinogenesis]' 'hepatocarcinogenesis [toxic course]' SubClassOf 'has part' some 'Grp78 signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004359 nagative regulation of mitophagy [mitochondrial disorder] 'nagative regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has result' some 'macrophage migration [mitochondrial disorder]' 'nagative regulation of mitophagy [mitochondrial disorder]' SubClassOf 'nagative regulation of mitophagy' 'nagative regulation of mitophagy [mitochondrial disorder]' SubClassOf 'negative regulation of ROS formation [hepatocarcinogenesis]' 'nagative regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has result' some 'malfunctioning of cytokinesis' http://purl.obolibrary.org/obo/TXPO_0004351 redox changes [mitochondrial disorder] 'redox changes [mitochondrial disorder]' SubClassOf 'redox change' 'redox changes [mitochondrial disorder]' SubClassOf 'BECN1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004350 mitochondria morphology change [mitochondrial disorder] 'mitochondria morphology change [mitochondrial disorder]' SubClassOf 'mitochondria morphology change' 'mitochondria morphology change [mitochondrial disorder]' SubClassOf 'Increasing glucagon level [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004345 mitochondrial membrane morphology changes 'mitochondrial membrane morphology changes' SubClassOf 'mitochondrial membrane morphology changes' 'mitochondrial membrane morphology changes' SubClassOf 'Increasing long-chain free fatty acid level [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004346 IL-1beta production [mitochondrial disorder] 'IL-1beta production [mitochondrial disorder]' SubClassOf 'has output' some 'IL-1B(canonical) [mitochondrial disorder]' 'IL-1beta production [mitochondrial disorder]' SubClassOf 'has output' some 'KIAA0101 inactivation' http://purl.obolibrary.org/obo/TXPO_0004341 cardiolipin peroxidation [mitochondrial disorder] 'cardiolipin peroxidation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of ATP transport [mitochondrial disorder]' 'cardiolipin peroxidation [mitochondrial disorder]' SubClassOf 'cardiolipin peroxidation' 'cardiolipin peroxidation [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing BCL-2 level [hepatocarcinogenesis]' 'cardiolipin peroxidation [mitochondrial disorder]' SubClassOf 'malondialdehyde [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004322 TLR9 signaling pathway [hepatocarcinogenesis] 'TLR9 signaling pathway [hepatocarcinogenesis]' SubClassOf 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004323 interleukin-6-mediated signaling pathway [Mitochondrial disorder] 'interleukin-6-mediated signaling pathway [Mitochondrial disorder]' SubClassOf 'interleukin-6-mediated signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004324 IL6 signaling [Mitochondrial disorder] 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has agent' some 'IL-6(human)[mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has result' some 'Iron accumulation [mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has pathway' some 'interleukin-6-mediated signaling pathway [Mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has participant' some 'didanosine [mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has participant' some 'IL-6(human)[mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has pathway' some 'interleukin-6-mediated signaling pathway' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has part' some 'interleukin-6 production [mitochondrial disorder]' 'IL6 signaling [Mitochondrial disorder]' SubClassOf 'has result' some 'Increasing ACSL1 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004321 TLR9 signaling pathway [Mitochondrial disorder] 'TLR9 signaling pathway [Mitochondrial disorder]' SubClassOf 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0000869 mitochondrial respiratory chain abnormality [Mitochondrial disorder] 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' SubClassOf 'has part' some 'Negative regulation of respiratory complex proteins synthesis' http://purl.obolibrary.org/obo/TXPO_0004399 HNF4A inactivation [hepatocarcinogenesis] 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'HNF4A inactivation' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' 'HNF4A inactivation [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004395 Increasing ACSL1 level 'Increasing ACSL1 level' SubClassOf 'has output' some 'ACSL1 (mol)' 'Increasing ACSL1 level' SubClassOf 'increasing quantity' 'Increasing ACSL1 level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing ACSL1 level' SubClassOf 'has result' some 'APC signal transduction pathway' 'Increasing ACSL1 level' SubClassOf 'has result' some 'STAT3(human) [hepatocarcinogenesis]' 'Increasing ACSL1 level' SubClassOf 'EPB41L3 (rat) [hepatocarcinogenesis]' 'Increasing ACSL1 level' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'Increasing ACSL1 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing ACSL1 level' SubClassOf 'has participant' some 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' http://purl.obolibrary.org/obo/TXPO_0004396 ACSL1 (mol) 'ACSL1 (mol)' SubClassOf 'molecule' 'ACSL1 (mol)' SubClassOf 'has part' some 'Pvt1 (human) [hepatocarcinogenesis]' 'ACSL1 (mol)' SubClassOf 'has participant' some 'Telomerase reverse transcriptase gene mutation' 'ACSL1 (mol)' SubClassOf 'negative regulation of apoptotic process' 'ACSL1 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'ACSL1 (mol)' SubClassOf 'has participant' some 'sorafenib resistance (process)' 'ACSL1 (mol)' SubClassOf 'has result' some 'TERT (canonical) [hepatocarcinogenesis]' 'ACSL1 (mol)' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004397 Increasing ACSL1 level [hepatocarcinogenesis] 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'ACSL1 (canonical) [hepatocarcinogenesis]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'HNF4A inactivation [hepatocarcinogenesis]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'Increasing ACSL1 level' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'iron accumulation' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has input' some 'iron atom' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Increasing ACSL1 level [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004398 ACSL1 (canonical) [hepatocarcinogenesis] 'ACSL1 (canonical) [hepatocarcinogenesis]' SubClassOf 'ACSL1 (mol)' 'ACSL1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'ACSL1 (canonical) [hepatocarcinogenesis]' SubClassOf 'has output' some 'HNF4A inactivation [hepatocarcinogenesis]' 'ACSL1 (canonical) [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004391 increasing production amount of reactive aldehyde [mitochondrial disorder] 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'increasing production amount of reactive aldehyde' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has output' some 'malondialdehyde [mitochondrial disorder]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has output' some '4-hydroxynonenal [mitochondrial disorder]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has output' some 'reactive aldehyde [mitochondrial disorder]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has participant' some 'tumor-associated macrophage' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has result' some 'Decreasing LDLRAD4 level' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has output' some 'negative regulation of signal transduction by p53 class mediator [[hepatocarcinogenesis]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing production amount of reactive aldehyde [mitochondrial disorder]' SubClassOf 'KIAA0101 tv1 (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004392 chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis] 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing VEGF level [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing BCL-2 level [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'chemokine (C-X-C motif) ligand 8 production' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has output' some 'CXCL8 (predicted)(human) [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'tumorigenesis' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'AGGF1 signal (primitive)' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'dysregulation of mitochondrion organization' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some '4-hydroxynonenal [mitochondrial disorder]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fialuridine' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'increasing mtDNA level' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Increasing cholesterol level [mitochondrial disorder]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'DNMT1 (rat) [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'PPARA(mouse) [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'ORC1 - inactive form (human) [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'panadiplon' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'lipoperoxidation [hepatocarcinogenesis]' 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some http://purl.obolibrary.org/obo/TXPO_0005138 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004393 Snail1 signaling [hepatocarcinogenesis] 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'Snail1 signaling (primitive)' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PROM1 level [hepatocarcinogenesis]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'SNAI1 (human) [hepatocarcinogenesis]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has output' some 'increasing blood glucose level [mitochondrial disorder]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has output' some 'FZD1 (mol)' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has output' some 'FOXO1 (canonical)[mitochondrial disorder]' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'EPB41L3 (mol)' 'Snail1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004394 Iron accumulation [mitochondrial disorder] 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has input' some 'iron atom' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'iron accumulation' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'OR3A4 (human) [hepatocarcinogenesis]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'C9ORF72 inactivation [mitochondrial disorder]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has output' some 'CXCL8 (predicted)(human) [hepatocarcinogenesis]' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'ACSL4 (mol)' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'Iron accumulation [mitochondrial disorder]' SubClassOf 'CXCR3 signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004390 tumorigenesis [hepatocarcinogenesis] 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'aflatoxin B1 [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'tumorigenesis' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some '2-acetamidofluorene [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'styrene oxide [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some '1-hydroxyanthraquinone' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'gemfibrozil [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'pyrethrins [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'aristolochic acid [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some '1,2-dichloropropane [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Monuron [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'alcohol [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Chlorendic Acid [hepatocarcinogenesis]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'tumorigenesis [hepatocarcinogenesis]' SubClassOf 'has participant' some 'decreasing glutathione level [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004388 fialuridine [mitochondrial disorder] 'fialuridine [mitochondrial disorder]' SubClassOf 'fialuridine' 'fialuridine [mitochondrial disorder]' SubClassOf 'stavudine' http://purl.obolibrary.org/obo/TXPO_0004389 Hypofunction of PPARGC1A gene expression [mitochondrial disorder] 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'has participant' some 'PPARGC1A (canonical) [mitochondrial disorder]' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'Hypofunction of PPARGC1A gene expression' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' SubClassOf 'mitochondria disorder dependent chemical compound' http://purl.obolibrary.org/obo/TXPO_0004385 didanosine [mitochondrial disorder] 'didanosine [mitochondrial disorder]' SubClassOf 'didanosine' 'didanosine [mitochondrial disorder]' SubClassOf 'mitochondria disorder dependent chemical compound' 'didanosine [mitochondrial disorder]' SubClassOf 'IL-6 (mol)' 'didanosine [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0004386 zidovudine [mitochondrial disorder] 'zidovudine [mitochondrial disorder]' SubClassOf 'zidovudine' 'zidovudine [mitochondrial disorder]' SubClassOf 'didanosine' http://purl.obolibrary.org/obo/TXPO_0004387 http://purl.obolibrary.org/obo/TXPO_0004387 SubClassOf 'stavudine' http://purl.obolibrary.org/obo/TXPO_0004387 SubClassOf 'zidovudine' http://purl.obolibrary.org/obo/TXPO_0004380 inflammasome activation [mitochondrial disorder] 'inflammasome activation [mitochondrial disorder]' SubClassOf 'has participant' some 'NLRP3 (canonical)[mitochondrial disorder]]' 'inflammasome activation [mitochondrial disorder]' SubClassOf 'has participant' some 'Increasing fructose level' http://purl.obolibrary.org/obo/TXPO_0004381 TNFΑ (canonical)[mitochondrial disorder] 'TNFΑ (canonical)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'TNFΑ (canonical)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0004382 HIF1A activation [mitochondrial disorder] 'HIF1A activation [mitochondrial disorder]' SubClassOf 'HIF1A activation' 'HIF1A activation [mitochondrial disorder]' SubClassOf 'has output' some 'HIF1A - activation state (canonical)[mitochondrial disorder]' 'HIF1A activation [mitochondrial disorder]' SubClassOf 'has output' some 'MST1 (canonical) [hepatocarcinogenesis]' 'HIF1A activation [mitochondrial disorder]' SubClassOf 'Hippo signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004383 inducible nitric oxide synthase production [mitochondrial disorder] 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has output' some 'NOS2 (canonical) [mitochondrial disorder]' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing production quantity of NO [mitochondrial disorder]' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'inducible nitric oxide synthase production' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has result' some 'increasing production quantity of RNS [mitochondrial disorder]' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'phospholipid peroxidation' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has output' some 'Chlorendic Acid' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has result' some 'PCNA (human) [hepatocarcinogenesis]' 'inducible nitric oxide synthase production [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing PCNA level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004377 Increasing HMGB1 level [mitochondrial disorder] 'Increasing HMGB1 level [mitochondrial disorder]' SubClassOf 'has output' some 'HMGB1 (canonical) [mitochondrial disorder]' 'Increasing HMGB1 level [mitochondrial disorder]' SubClassOf 'Increasing HMGB1 level' 'Increasing HMGB1 level [mitochondrial disorder]' SubClassOf 'has output' some 'IFN alpha inactivation [hepatocarcinogenesis]' 'Increasing HMGB1 level [mitochondrial disorder]' SubClassOf 'IFN alpha inactivation' http://purl.obolibrary.org/obo/TXPO_0004378 TLR4 signaling [mitochondrial disorder] 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'TLR4 signaling (primitive)' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has result' some 'cytolysis [mitochondrial disorder]' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has agent' some 'TLR4 (canonical) [mitochondrial disorder]' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has pathway' some 'TLR4 signaling pathway [mitochondrial disorder]' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has pathway' some 'TLR4 signaling pathway' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'YAP signal transduction pathway' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has result' some 'YAP signaling (primitive)' 'TLR4 signaling [mitochondrial disorder]' SubClassOf 'has agent' some 'YAP1 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004373 increasing demand for response to oxidative stress [mitochondrial disorder] 'increasing demand for response to oxidative stress [mitochondrial disorder]' SubClassOf 'has result' some 'Hypofunction of PPARGC1A gene expression [mitochondrial disorder]' 'increasing demand for response to oxidative stress [mitochondrial disorder]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004374 ketone body biosynthetic process [mitochondrial disorder] 'ketone body biosynthetic process [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing ketone body level [mitochondrial disorder]' 'ketone body biosynthetic process [mitochondrial disorder]' SubClassOf 'has result' some 'negative regulation of phosphorylation' http://purl.obolibrary.org/obo/TXPO_0004375 Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder] 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' SubClassOf 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation' 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' SubClassOf 'negatively regulates' some 'mitochondrial respiratory chain complex I subunit phosphorylation' 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' SubClassOf 'iron metabolic dysfunction' 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' SubClassOf 'negatively regulates' some 'Increasing iron uptake level' http://purl.obolibrary.org/obo/TXPO_0004371 gluconeogenesis [mitochondrial disorder] 'gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'increasing blood glucose level [mitochondrial disorder]' 'gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'HIF1A(canonical) [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004372 lipid biosynthetic process [mitochondrial disorder] 'lipid biosynthetic process [mitochondrial disorder]' SubClassOf 'has result' some 'increasing lipid concentration [mitochondrial disorder]' 'lipid biosynthetic process [mitochondrial disorder]' SubClassOf 'has result' some 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004366 hyperfunction of CYP2E1 gene expression [mitochondrial disorder] 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' SubClassOf 'Hyperfunction of CYP2E1 gene expression' 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' SubClassOf 'Removing damaged DNA stress' http://purl.obolibrary.org/obo/TXPO_0004367 hyperfunction of gluconeogenesis [mitochondrial disorder] 'hyperfunction of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'glucose homeostasis imbalance [mitochondrial disorder]' 'hyperfunction of gluconeogenesis [mitochondrial disorder]' SubClassOf 'hyperfunction of gluconeogenesis' 'hyperfunction of gluconeogenesis [mitochondrial disorder]' SubClassOf 'Increase in mitochondrial calcium level [mitochondrial disorder]' 'hyperfunction of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of glutathione transport into mitochondria' http://purl.obolibrary.org/obo/TXPO_0004368 Increasing damaged mitochondria [mitochondrial disorder] 'Increasing damaged mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'release of inflammatory DAMPs [mitochondrial disorder]' 'Increasing damaged mitochondria [mitochondrial disorder]' SubClassOf 'increasing damaged mitochondria' 'Increasing damaged mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'GJA1 (mol)' 'Increasing damaged mitochondria [mitochondrial disorder]' SubClassOf 'FZD9 (mol)' http://purl.obolibrary.org/obo/TXPO_0004369 increasing CPT1 level [mitochondrial disorder] 'increasing CPT1 level [mitochondrial disorder]' SubClassOf 'has output' some 'CPT1(canonical) [mitochondrial disorder]' 'increasing CPT1 level [mitochondrial disorder]' SubClassOf 'increasing CPT1 level' 'increasing CPT1 level [mitochondrial disorder]' SubClassOf 'metastasis [hepatocarcinogenesis]' 'increasing CPT1 level [mitochondrial disorder]' SubClassOf 'has output' some 'CXCR3 signaling [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004363 panadiplon [mitochondrial disorder] 'panadiplon [mitochondrial disorder]' SubClassOf 'panadiplon' 'panadiplon [mitochondrial disorder]' SubClassOf 'reactive aldehyde [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004436 Increasing BCL-2 level [hepatocarcinogenesis] 'Increasing BCL-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'Increasing BCL-2 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing BCL-2 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing BCL-2 level [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing BCL-2 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004437 C9ORF72 inactivation 'C9ORF72 inactivation' SubClassOf 'inactivation' 'C9ORF72 inactivation' SubClassOf 'has output' some ('C9orf72 (mol)' and ('has quality' some 'inactive')) 'C9ORF72 inactivation' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004438 C9ORF72 inactivation [mitochondrial disorder] 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'C9orf72 (predicted)(human) [mitochondrial damage]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Dysregulation of mitochondrion organization' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing mitochondrial membrane potential [mitochondrial disorder]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'positive regulation of mitophagy [mitochondrial disorder]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'positive regulation of autophagy [mitochondrial disorder]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'C9ORF72 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004439 C9orf72 (predicted)(human) [mitochondrial damage] 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'inactive' 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'predicted (quality)' 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'has related human gene' some 'C9orf72' 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'C9orf72 (predicted)(human) [mitochondrial damage]' 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'has output' some ('C9orf72 (mol)' and ('has quality' some 'inactive')) 'C9orf72 (predicted)(human) [mitochondrial damage]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004432 Grp78 signaling (primitive) [hepatocarcinogenesis] 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'Grp78 signal (primitive)' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Grp78 signal transduction pathway' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'GRP78 (canonical)[hepatocarcinogenesis]' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'cisplatin resistance [hepatocarcinogenesis]' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'ATF6 signaling (primitive) [ATF6 pathway]' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Negative regulation of ATP transport [mitochondrial disorder]' 'Grp78 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Negative regulation of ATP transpot' http://purl.obolibrary.org/obo/TXPO_0004433 Negative regulation of ATP transpot 'Negative regulation of ATP transpot' SubClassOf 'negative regulation of transport' 'Negative regulation of ATP transpot' SubClassOf 'family of' some 'ATF' 'Negative regulation of ATP transpot' SubClassOf 'ATF6 (mol)' 'Negative regulation of ATP transpot' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004434 Negative regulation of ATP transport [mitochondrial disorder] 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'Negative regulation of ATP transpot' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'increasing FGF21 level' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing HGF level' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'has pathway' some 'increasing FGF21 level [mitochondrial disorder]' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'has participant' some 'WNT signaling (primitive) [hepatocarcinogenesis]' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'Negative regulation of ATP transport [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004435 Increasing BCL-2 level 'Increasing BCL-2 level' SubClassOf 'increasing quantity' 'Increasing BCL-2 level' SubClassOf 'negative regulation of transport' http://purl.obolibrary.org/obo/TXPO_0004430 PMAIP1 inactivation [hepatocarcinogenesis] 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'PMAIP1 inactivation' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'ATF4' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'family of' some 'ATF' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'PMAIP1 inactivation [hepatocarcinogenesis]' SubClassOf 'TERT (mol)' http://purl.obolibrary.org/obo/TXPO_0004431 ATF6 signaling (primitive) [hepatocarcinogenesis] 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'ATF6 signaling (primitive) [ATF6 pathway]' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Grp78 signaling (primitive) [hepatocarcinogenesis]' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has output' some 'Increasing PVT1 level [hepatocarcinogenesis]' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Pvt1 (human) [hepatocarcinogenesis]' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'Increasing PVT1 level' 'ATF6 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' http://purl.obolibrary.org/obo/TXPO_0004429 ATF4 - inactive form (human) [hepatocarcinogenesis] 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'ATF4' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'family of' some 'ATF' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'ATF4(human) [hepatocarcinogenesis]' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'ATF4 inactivation [hepatocarcinogenesis]' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'PMAIP1 inactivation [hepatocarcinogenesis]' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' 'ATF4 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004425 negative regulation of APC signaling [hepatocarcinogenesis] 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'APC signal transduction pathway' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'negative regulation of APC signaling' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of EPCR signaling' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'negative regulation of APC signaling' 'negative regulation of APC signaling [hepatocarcinogenesis]' SubClassOf 'negative regulation of signaling' http://purl.obolibrary.org/obo/TXPO_0004426 negative regulation of EPCR signaling 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'EPCR signaling (primitive)' 'negative regulation of EPCR signaling' SubClassOf 'negative regulation of EPCR signaling' 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'EPCR signal transduction pathway' 'negative regulation of EPCR signaling' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'negative regulation of EPCR signaling' SubClassOf 'has result' some 'ATF4 inactivation' 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'negative regulation of APC signaling' 'negative regulation of EPCR signaling' SubClassOf 'negative regulation of APC signaling [hepatocarcinogenesis]' 'negative regulation of EPCR signaling' SubClassOf 'negatively regulates' some 'APC signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004427 ATF4 inactivation 'ATF4 inactivation' SubClassOf 'has output' some ('ATF4 (mol)' and ('has quality' some 'inactive')) 'ATF4 inactivation' SubClassOf 'inactivation' 'ATF4 inactivation' SubClassOf 'negatively regulates' some 'inflammatory response [hepatocarcinogenesis]' 'ATF4 inactivation' SubClassOf 'negatively regulates' some 'increasing demand for response to ER stress [hepatocarcinogenesis]' 'ATF4 inactivation' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'ATF4 inactivation' SubClassOf 'increasing demand for response to oxidative stress [hepatocarcinogenesis]' 'ATF4 inactivation' SubClassOf 'has participant' some 'FAK signal transduction pathway' 'ATF4 inactivation' SubClassOf 'liver carcinogenesis dependent process' 'ATF4 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004428 ATF4 inactivation [hepatocarcinogenesis] 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'ATF4 - inactive form (human) [hepatocarcinogenesis]' 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'ATF4 inactivation' 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'PMAIP1 inactivation [hepatocarcinogenesis]' 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some ('ATF4 (mol)' and ('has quality' some 'inactive')) 'ATF4 inactivation [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004421 epithelial to mesenchymal transition [hepatocarcinogenesis] 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'epithelial to mesenchymal transition' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor malignancy alteration [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has part' some 'Notch signaling [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has input' some 'saturated fatty acid' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'has input' some '1,2-dichloropropane [hepatocarcinogenesis]' 'epithelial to mesenchymal transition [hepatocarcinogenesis]' SubClassOf 'saturated fatty acid [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004422 APC signal transduction pathway 'APC signal transduction pathway' SubClassOf 'signaling pathway' 'APC signal transduction pathway' SubClassOf 'has participant' some 'positive regulation of arachidonic acid metabolic process' 'APC signal transduction pathway' SubClassOf 'liver carcinogenesis dependent process' 'APC signal transduction pathway' SubClassOf 'has result' some 'ACSL4 (mol)' 'APC signal transduction pathway' SubClassOf 'has result' some 'CAR (mouse) [hepatocarcinogenesis]' 'APC signal transduction pathway' SubClassOf 'epithelial to mesenchymal transition' 'APC signal transduction pathway' SubClassOf 'has result' some 'induction of genomic instability' 'APC signal transduction pathway' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'APC signal transduction pathway' SubClassOf 'has result' some 'Increasing CXCR4 level' http://purl.obolibrary.org/obo/TXPO_0004423 APC signaling (primitive) 'APC signaling (primitive)' SubClassOf 'has pathway' some 'APC signal transduction pathway' 'APC signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'APC signaling (primitive)' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004424 negative regulation of APC signaling 'negative regulation of APC signaling' SubClassOf 'negatively regulates' some 'APC signal transduction pathway' 'negative regulation of APC signaling' SubClassOf 'negative regulation of signaling' 'negative regulation of APC signaling' SubClassOf 'negatively regulates' some 'APC signaling (primitive)' 'negative regulation of APC signaling' SubClassOf 'has pathway' some 'APC signaling (primitive)' 'negative regulation of APC signaling' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004420 Metalloprotease activation [hepatocarcinogenesis] 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'metalloprotease activation' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has input' some 'MMP2(canonical) [hepatocarcinogenesis]' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has input' some 'MMP9(canonical) [hepatocarcinogenesis]' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'p38 signaling (primitive)' 'Metalloprotease activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' http://purl.obolibrary.org/obo/TXPO_0004418 TOR signaling (primitive)　[hepatocarcinogenesis] 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CCND1 level [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'TOR signaling (primitive)' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'neovascularization [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'response to hypoxia [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PCNA level [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TOR signaling' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'has result' some 'PPARalpha activation [hepatocarcinogenesis]' 'TOR signaling (primitive)　[hepatocarcinogenesis]' SubClassOf 'Increasing MIR135A level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004419 p38 signaling (primitive) [hepatocarcinogenesis] 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'p38 signaling (primitive)' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'CDT1 - inactive form (human) [hepatocarcinogenesis]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of activation' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing PROC level' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'negative regulation of caspase-3 activation' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TOR signaling' 'p38 signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'TOR signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004414 negative regulation of AKT signaling [mitochondrial disorder] 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has result' some 'Malfunctioning of insulin signaling [mitochondrial disorder]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'negative regulation of protein kinase B signaling' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has part' some 'AGGF1 signaling [hepatocarcinogenesis]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has participant' some 'AGGF1 (predicted)(human) [hepatocarcinogenesis]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'SFRP1 (human) [hepatocarcinogenesis]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'negative regulation of AKT signaling [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004415 AKT signaling (primitive) [hepatocarcinogenesis] 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'AKT signaling (primitive)' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'TOR signaling (primitive)　[hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'p38 signaling (primitive) [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'GSK3beta signal (primitive) [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Metalloprotease activation [hepatocarcinogenesis]' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'AKT signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'OR3A4' http://purl.obolibrary.org/obo/TXPO_0004416 GSK3beta signal (primitive) [hepatocarcinogenesis] 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'beta-catenin signaling (primitive) [hepatocarcinogenesis]' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'GSK3beta signal (primitive)' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Malfunctioning of insulin signaling [mitochondrial disorder]' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'negative regulation of protein kinase B signaling' 'GSK3beta signal (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004417 Increasing IL-6 level [hepatocarcinogenesis] 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'JAK signaling (primitive) [hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'IL-6(human)[hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'Increasing IL-6 level' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'AKT signaling (primitive)' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'TOR signaling (primitive)　[hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'p38 signaling (primitive) [hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'increasing production amount of reactive aldehyde [mitochondrial disorder]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Metalloprotease activation [hepatocarcinogenesis]' 'Increasing IL-6 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004410 Increasing AGGF1 level [hepatocarcinogenesis] 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing VEGF level [hepatocarcinogenesis]' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'Increasing AGGF1 level' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'AGGF1 (predicted)(human) [hepatocarcinogenesis]' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'has agent' some 'OR3A4 (human) [hepatocarcinogenesis]' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'AGGF1 signaling [hepatocarcinogenesis]' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'Increasing triol level' 'Increasing AGGF1 level [hepatocarcinogenesis]' SubClassOf 'positively regulates' some 'arachidonic acid metabolism' http://purl.obolibrary.org/obo/TXPO_0004411 Increasing VEGF level [hepatocarcinogenesis] 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'has output' some 'VEGF (canonical) [hepatocarcinogenesis]' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'has result' some 'neovascularization [hepatocarcinogenesis]' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'Increasing VEGF level' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'has output' some 'AGGF1 (mol)' 'Increasing VEGF level [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004412 AGGF1 signaling [hepatocarcinogenesis] 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'AGGF1 (predicted)(human) [hepatocarcinogenesis]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'AGGF1 signal (primitive)' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has agent' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'OR3A4 (human) [hepatocarcinogenesis]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of AKT signaling [mitochondrial disorder]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'has output' some 'AGGF1 (predicted)(human) [hepatocarcinogenesis]' 'AGGF1 signaling [hepatocarcinogenesis]' SubClassOf 'Increasing VEGF level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004413 OR3A4 (human) [hepatocarcinogenesis] 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'OR3A4' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'Tumor suppressor gene mutation' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'negative regulation of actin cytoskeleton organization' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'OR3A4 (human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'acetyl-CoA biosynthetic process' http://purl.obolibrary.org/obo/TXPO_0004407 Increasing COX-2 level [hepatocarcinogenesis] 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'COX-2 (mol)' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of arachidonic acid metabolic process' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'Increasing COX-2 level' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing AGGF1 level' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'positive regulation of arachidonic acid metabolic process' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'Increasing ACSL4 level [hepatocarcinogenesis]' 'Increasing COX-2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing AGGF1 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004408 positive regulation of arachidonic acid metabolic process 'positive regulation of arachidonic acid metabolic process' SubClassOf 'liver carcinogenesis dependent process' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'positive regulation of arachidonic acid metabolic process' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'positively regulates' some 'arachidonic acid metabolism' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'PPARGC1A (mol)' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'ACSL4 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004409 Increasing AGGF1 level 'Increasing AGGF1 level' SubClassOf 'has output' some 'AGGF1 (mol)' 'Increasing AGGF1 level' SubClassOf 'increasing quantity' 'Increasing AGGF1 level' SubClassOf 'has output' some 'chemokine (C-X-C motif) ligand 8 production' 'Increasing AGGF1 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing AGGF1 level' SubClassOf 'has result' some 'Increasing AGGF1 level [hepatocarcinogenesis]' 'Increasing AGGF1 level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing AGGF1 level' SubClassOf 'negative regulation of cellular senescence [hepatocarcinogenesis]' 'Increasing AGGF1 level' SubClassOf 'has result' some 'ACSL4 (mol)' http://purl.obolibrary.org/obo/TXPO_0004403 Increasing ACSL4 level 'Increasing ACSL4 level' SubClassOf 'increasing quantity' 'Increasing ACSL4 level' SubClassOf 'has output' some 'ACSL4 (mol)' 'Increasing ACSL4 level' SubClassOf 'positive regulation of cell division' 'Increasing ACSL4 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing ACSL4 level' SubClassOf 'has participant' some 'cyproterone acetate [hepatocarcinogenesis]' 'Increasing ACSL4 level' SubClassOf 'has result' some 'IP-10 signaling (primitive)' 'Increasing ACSL4 level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004404 ACSL4 (mol) 'ACSL4 (mol)' SubClassOf 'molecule' 'ACSL4 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'ACSL4 (mol)' SubClassOf 'has input' some ('cell' and ('has quality' some 'neoplastic (quality)')) 'ACSL4 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'ACSL4 (mol)' SubClassOf 'tumor cell invasion' http://purl.obolibrary.org/obo/TXPO_0004405 Increasing ACSL4 level [hepatocarcinogenesis] 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'HNF4A inactivation [hepatocarcinogenesis]' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of arachidonic acid metabolic process' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'Increasing ACSL4 level' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing COX-2 level [hepatocarcinogenesis]' 'Increasing ACSL4 level [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004406 ACSL4 (canonical) [hepatocarcinogenesis] 'ACSL4 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'ACSL4 (canonical) [hepatocarcinogenesis]' SubClassOf 'ACSL4 (mol)' 'ACSL4 (canonical) [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004400 negative regulation of apoptotic process [hepatocarcinogenesis] 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'negative regulation of apoptotic process' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell survial [hepatocarcinogenesis]' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has output' some 'positive regulation of cell division [hepatocarcinogenesis]' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'ACSL1 (canonical) [hepatocarcinogenesis]' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' 'negative regulation of apoptotic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' http://purl.obolibrary.org/obo/TXPO_0004401 positive regulation of cell division [hepatocarcinogenesis] 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'has participant' some 'chloroethene [hepatocarcinogenesis]' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'has result' some 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'positive regulation of cell division' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'HNF4A inactivation [hepatocarcinogenesis]' 'positive regulation of cell division [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004402 tumor cell invasion [hepatocarcinogenesis] 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'has input' some ('cell' and ('has quality' some 'neoplastic (quality)')) 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'tumor cell invasion' 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'has result' some 'PPARalpha activation [hepatocarcinogenesis]' 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'has output' some 'IGFBP3 inactivation [hepatocarcinogenesis]' 'tumor cell invasion [hepatocarcinogenesis]' SubClassOf 'IGFBP3 inactivation' http://purl.obolibrary.org/obo/TXPO_0004476 CXCR3(canonical) [hepatocarcinogenesis] 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'CXCR3 (mol)' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'CXCR3 signaling (primitive)' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'has input' some 'CXCL8 (predicted)(human) [hepatocarcinogenesis]' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CXCR3(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004477 endothelial progenitor cell mobilization [hepatocarcinogenesis] 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' SubClassOf 'endothelial progenitor cell mobilization' 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' SubClassOf 'has result' some 'neovascularization [hepatocarcinogenesis]' 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' SubClassOf 'negative regulation of cellular senescence' 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004478 CXCR3 signal transduction pathway 'CXCR3 signal transduction pathway' SubClassOf 'signaling pathway' 'CXCR3 signal transduction pathway' SubClassOf 'has output' some 'CXCL8 (mol)' 'CXCR3 signal transduction pathway' SubClassOf 'chemokine production' http://purl.obolibrary.org/obo/TXPO_0004479 Increasing CXCR4 level 'Increasing CXCR4 level' SubClassOf 'has output' some 'CXCR4 (mol)' 'Increasing CXCR4 level' SubClassOf 'increasing quantity' 'Increasing CXCR4 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing CXCR4 level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing CXCR4 level' SubClassOf 'metastasis' http://purl.obolibrary.org/obo/TXPO_0004472 chemokine (C-X-C motif) ligand 8 production 'chemokine (C-X-C motif) ligand 8 production' SubClassOf 'chemokine production' 'chemokine (C-X-C motif) ligand 8 production' SubClassOf 'has output' some 'CXCL8 (mol)' 'chemokine (C-X-C motif) ligand 8 production' SubClassOf 'PPARGC1A (mol)' 'chemokine (C-X-C motif) ligand 8 production' SubClassOf 'COX-2 (mol)' http://purl.obolibrary.org/obo/TXPO_0004473 metastasis [hepatocarcinogenesis] 'metastasis [hepatocarcinogenesis]' SubClassOf 'metastasis' 'metastasis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'metastasis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'metastasis [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004474 CXCR3 signaling [hepatocarcinogenesis] 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'endothelial progenitor cell mobilization [hepatocarcinogenesis]' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'CXCR3 signaling (primitive)' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'CXCR3 signal transduction pathway' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CXCR3(canonical) [hepatocarcinogenesis]' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'CXCR3 signaling [hepatocarcinogenesis]' SubClassOf 'Cpt1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004475 CXCR3 signaling (primitive) 'CXCR3 signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'CXCR3 signaling (primitive)' SubClassOf 'has participant' some 'CXCR3 (mol)' 'CXCR3 signaling (primitive)' SubClassOf 'has pathway' some 'CXCR3 signal transduction pathway' 'CXCR3 signaling (primitive)' SubClassOf 'decreasing quantity' 'CXCR3 signaling (primitive)' SubClassOf 'has input' some 'CXCL8 (mol)' http://purl.obolibrary.org/obo/TXPO_0004470 Decreasing CXCL8 level 'Decreasing CXCL8 level' SubClassOf 'has input' some 'CXCL8 (predicted)(human) [hepatocarcinogenesis]' 'Decreasing CXCL8 level' SubClassOf 'Decreasing CXCL8 level' 'Decreasing CXCL8 level' SubClassOf 'has result' some 'negative regulation of cellular senescence [hepatocarcinogenesis]' 'Decreasing CXCL8 level' SubClassOf 'DNA damage [hepatocarcinogenesis]' 'Decreasing CXCL8 level' SubClassOf 'has result' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004471 negative regulation of cellular senescence [hepatocarcinogenesis] 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'negative regulation of cellular senescence' 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'increasing quantity' 'negative regulation of cellular senescence [hepatocarcinogenesis]' SubClassOf 'has output' some 'COX-2 (mol)' http://purl.obolibrary.org/obo/TXPO_0004469 Decreasing CXCL8 level 'Decreasing CXCL8 level' SubClassOf 'decreasing quantity' 'Decreasing CXCL8 level' SubClassOf 'has input' some 'CXCL8 (mol)' 'Decreasing CXCL8 level' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005075 'Decreasing CXCL8 level' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004465 Removing damaged DNA stress [hepatocarcinogenesis] 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'has result' some 'PMAIP1 inactivation [hepatocarcinogenesis]' 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'Removing damaged DNA stress' 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'CDK2 (mol)' 'Removing damaged DNA stress [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004466 Increasing COX-2 level 'Increasing COX-2 level' SubClassOf 'has output' some 'COX-2 (mol)' 'Increasing COX-2 level' SubClassOf 'increasing quantity' 'Increasing COX-2 level' SubClassOf 'inactivation' 'Increasing COX-2 level' SubClassOf 'has output' some ('increasing CPT1 level' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004467 increasing CPT1 level 'increasing CPT1 level' SubClassOf 'increasing quantity' 'increasing CPT1 level' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004468 CPT1(canonical) [mitochondrial disorder] 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'Cpt1 (mol)' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'Increasing COX-2 level' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Decreasing CXCL8 level' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'has output' some 'Decreasing CXCL8 level' 'CPT1(canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004461 CDT1 inactivation [hepatocarcinogenesis] 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'inactivation' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some ('CDT1 (mol)' and ('has quality' some 'inactive')) 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'CDK2 (human) [hepatocarcinogenesis]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'CDT1 (mol)' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004462 CDT1 (mol) 'CDT1 (mol)' SubClassOf 'molecule' 'CDT1 (mol)' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'CDT1 (mol)' SubClassOf 'has quality' some 'inactive' 'CDT1 (mol)' SubClassOf 'CDK1 (predicted)(human) [mitochondrial damage]' 'CDT1 (mol)' SubClassOf 'has related human gene' some 'CDK1' 'CDT1 (mol)' SubClassOf 'has quality' some 'predicted (quality)' http://purl.obolibrary.org/obo/TXPO_0004463 CDT1 inactivation [hepatocarcinogenesis] 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'CDT1 inactivation [hepatocarcinogenesis]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'CDT1 - inactive form (human) [hepatocarcinogenesis]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Removing damaged DNA stress [hepatocarcinogenesis]' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'CDK2 (mol)' 'CDT1 inactivation [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004464 CDT1 - inactive form (human) [hepatocarcinogenesis] 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'CDT1 (human) [hepatocarcinogenesis]' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'CDT1 inactivation [hepatocarcinogenesis]' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'Removing damaged DNA stress [hepatocarcinogenesis]' 'CDT1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004460 CDK2 (human) [hepatocarcinogenesis] 'CDK2 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'CDK2 (human) [hepatocarcinogenesis]' SubClassOf 'CDK2 (mol)' 'CDK2 (human) [hepatocarcinogenesis]' SubClassOf 'has output' some ('NEAT1 (mol)' and ('has quality' some 'inactive')) 'CDK2 (human) [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004458 Increasing CDK2 level 'Increasing CDK2 level' SubClassOf 'increasing quantity' 'Increasing CDK2 level' SubClassOf 'has output' some 'CDK2 (mol)' 'Increasing CDK2 level' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Increasing CDK2 level' SubClassOf 'Cyclin D1 (mol)' 'Increasing CDK2 level' SubClassOf 'has related human gene' some 'CCND1' http://purl.obolibrary.org/obo/TXPO_0004459 Increasing CDK2 level [hepatocarcinogenesis] 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'CDK2 (human) [hepatocarcinogenesis]' 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'Increasing CDK2 level' 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'positive regulation of cell cycle' 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing ACSL4 level' 'Increasing CDK2 level [hepatocarcinogenesis]' SubClassOf 'positively regulates' some 'cell cycle' http://purl.obolibrary.org/obo/TXPO_0004454 positive regulation of cell cycle [hepatocarcinogenesis] 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'positive regulation of cell cycle' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'positively regulates' some 'cell cycle' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'has role' some 'respiratory chain inhibitor role' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'has role' some 'fibrosis inhibitor' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'tetrachloromethane' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of immune response' 'positive regulation of cell cycle [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004455 CDK1 inactivation 'CDK1 inactivation' SubClassOf 'has output' some ('NEAT1 (mol)' and ('has quality' some 'inactive')) 'CDK1 inactivation' SubClassOf 'inactivation' 'CDK1 inactivation' SubClassOf 'liver cancer dependent chemical entity' http://purl.obolibrary.org/obo/TXPO_0004456 CDK1 inactivation [mitochondrial disorder] 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'CDK1 inactivation' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'Cyclin D1 (mol)' 'CDK1 inactivation [mitochondrial disorder]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004457 CDK1 - inactive form (predicted) (human) [mitochondrial damage] 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has quality' some 'inactive' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has quality' some 'predicted (quality)' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has related human gene' some 'CDK1' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'CDK1 (predicted)(human) [mitochondrial damage]' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'liver carcinogenesis dependent process' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'CDK1 inactivation [mitochondrial disorder]' 'CDK1 - inactive form (predicted) (human) [mitochondrial damage]' SubClassOf 'has output' some 'Increasing CDK2 level' http://purl.obolibrary.org/obo/TXPO_0004450 hepatocarcinogenesis dependent chemical compound 'hepatocarcinogenesis dependent chemical compound' SubClassOf 'liver cancer dependent chemical entity' 'hepatocarcinogenesis dependent chemical compound' SubClassOf 'YAP1 (mol)' 'hepatocarcinogenesis dependent chemical compound' SubClassOf 'has quality' some 'active' http://purl.obolibrary.org/obo/TXPO_0004451 CCND1増加 Increasing CCND1 level 'CCND1増加' SubClassOf 'has output' some 'Cyclin D1 (mol)' 'CCND1増加' SubClassOf 'increasing quantity' 'CCND1増加' SubClassOf 'has participant' some 'CCL2 (mol)' 'CCND1増加' SubClassOf 'signaling [biological] (primitive)' 'CCND1増加' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0038151 http://purl.obolibrary.org/obo/TXPO_0004452 Increasing CCND1 level [hepatocarcinogenesis] 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'CCND1 (human) [hepatocarcinogenesis]' 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has part' some 'CCL2 production [Hepatocarcinogenesis]' 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has pathway' some http://purl.obolibrary.org/obo/GO_0038151 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL2(human)[hepatocarcinogenesis]' 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'CCND1 (human) [hepatocarcinogenesis]' 'Increasing CCND1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor-associated macrophage activation@hepatocarcinogenesis' http://purl.obolibrary.org/obo/TXPO_0004453 CCND1 (human) [hepatocarcinogenesis] 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CCND1' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'Cyclin D1 (mol)' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'hepatic cirrhosis' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'CCND1 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'FOXO1 activation' http://purl.obolibrary.org/obo/TXPO_0004447 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis] '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'phenobarbital [hepatocarcinogenesis]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'has output' some 'hepatocarcinogenesis dependent chemical compound' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL4 [hepatocarcinogenesis]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004448 CAR - activation state (mouse) [hepatocarcinogenesis] 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'CAR (mouse) [hepatocarcinogenesis]' 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'active' 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'CAR - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'phenobarbital' http://purl.obolibrary.org/obo/TXPO_0004449 CCL4 [hepatocarcinogenesis] 'CCL4 [hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of immune response' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'tetrachloromethane' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'has role' some 'fibrosis inhibitor' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'has role' some 'respiratory chain inhibitor role' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'CCL4 [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'CCL4 [hepatocarcinogenesis]' SubClassOf 'Increasing VEGF level' 'CCL4 [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004443 Increasing mitochondrial membrane potential [mitochondrial disorder] 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'occurs in' only 'mitochondrial membrane' 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'Increasing membrane potential' 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'positive regulation of mitophagy' 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'has result' some 'mitohagy [Mitochondrial disorder]' 'Increasing mitochondrial membrane potential [mitochondrial disorder]' SubClassOf 'positively regulates' some 'mitohagy' http://purl.obolibrary.org/obo/TXPO_0004444 CAR activation 'CAR activation' SubClassOf 'molecular activation' 'CAR activation' SubClassOf 'has output' some ('CAR (mol)' and ('has quality' some 'active')) 'CAR activation' SubClassOf 'Increasing long-chain free fatty acid level' 'CAR activation' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'CAR activation' SubClassOf 'mitochondrial disorder dependent process' 'CAR activation' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004445 CAR activation [hepatocarcinogenesis] 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'phenobarbital [hepatocarcinogenesis]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'CAR activation' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has output' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has participant' some '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene [hepatocarcinogenesis]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'Increasing saturated fatty acid level [mitochondrial disorder]' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'occurs in' only 'mitochondrial membrane' 'CAR activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004446 phenobarbital [hepatocarcinogenesis] 'phenobarbital [hepatocarcinogenesis]' SubClassOf 'phenobarbital' 'phenobarbital [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'phenobarbital [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'phenobarbital [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'phenobarbital [hepatocarcinogenesis]' SubClassOf 'molecular activation' 'phenobarbital [hepatocarcinogenesis]' SubClassOf 'has output' some ('CAR (mol)' and ('has quality' some 'active')) http://purl.obolibrary.org/obo/TXPO_0004440 positive regulation of autophagy [mitochondrial disorder] 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'positive regulation of autophagy' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has result' some 'autophagy [mitochondrial disorder]' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has result' some 'CAR activation' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has result' some 'Dysregulation of mitochondrion organization' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has result' some 'CAR activation [hepatocarcinogenesis]' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has output' some 'positive regulation of mitophagy [mitochondrial disorder]' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'C9orf72 (predicted)(human) [mitochondrial damage]' 'positive regulation of autophagy [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing mitochondrial membrane potential [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004441 positive regulation of mitophagy [mitochondrial disorder] 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has result' some 'mitohagy [Mitochondrial disorder]' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'positively regulates' some 'mitohagy' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'positive regulation of mitophagy' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has quality' some 'predicted (quality)' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'C9orf72 (predicted)(human) [mitochondrial damage]' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'positive regulation of mitophagy [mitochondrial disorder]' SubClassOf 'has related human gene' some 'C9orf72' http://purl.obolibrary.org/obo/TXPO_0004442 Dysregulation of mitochondrion organization 'Dysregulation of mitochondrion organization' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'Dysregulation of mitochondrion organization' SubClassOf 'dysregulation of mitochondrion organization' 'Dysregulation of mitochondrion organization' SubClassOf 'has result' some 'Increasing uric acid level [mitochondrial disorder]' 'Dysregulation of mitochondrion organization' SubClassOf 'positive regulation of autophagy' http://purl.obolibrary.org/obo/TXPO_0004913 styrene oxide [hepatocarcinogenesis] 'styrene oxide [hepatocarcinogenesis]' SubClassOf 'styrene oxide' 'styrene oxide [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'styrene oxide [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'styrene oxide [hepatocarcinogenesis]' SubClassOf 'CYP3A4 (mol)' http://purl.obolibrary.org/obo/TXPO_0004914 Negative regulation of sphingolipid metabolic process 'Negative regulation of sphingolipid metabolic process' SubClassOf 'negatively regulates' some 'sphingolipid metabolic process' 'Negative regulation of sphingolipid metabolic process' SubClassOf 'negative regulation process' 'Negative regulation of sphingolipid metabolic process' SubClassOf 'PPARGC1A (mol)' 'Negative regulation of sphingolipid metabolic process' SubClassOf 'CYP3A5 (mol)' http://purl.obolibrary.org/obo/TXPO_0004915 Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis] 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'sphingolipid metabolic process' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'Negative regulation of sphingolipid metabolic process' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005078 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP3A7' 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004916 ceramide accumulation [mitochondrial disorder] 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'PKC activation [mitochondrial disorder]' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'ceramide acumulation' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'Cyp1A1 (mol)' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'has related human gene' some 'CYP1A1' 'ceramide accumulation [mitochondrial disorder]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004910 drug resistance 'drug resistance' SubClassOf 'decreasing sensitivity' 'drug resistance' SubClassOf 'PPARGC1A (mol)' 'drug resistance' SubClassOf 'has related human gene' some 'CYP1A2' 'drug resistance' SubClassOf 'Cyp1A2 (mol)' http://purl.obolibrary.org/obo/TXPO_0004911 diacylglycerol acumulation 'diacylglycerol acumulation' SubClassOf 'has input' some 'diacylglycerol' 'diacylglycerol acumulation' SubClassOf 'lipid storage' 'diacylglycerol acumulation' SubClassOf 'PPARGC1A (mol)' 'diacylglycerol acumulation' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005076 'diacylglycerol acumulation' SubClassOf 'has related human gene' some 'CYP2A13' http://purl.obolibrary.org/obo/TXPO_0004912 diacylglycerol accumulation [mitochondrial disorder] 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'has result' some 'PKC activation [mitochondrial disorder]' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'diacylglycerol acumulation' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'has input' some 'diacylglycerol' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005077 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'has related human gene' some 'CYP2A6' 'diacylglycerol accumulation [mitochondrial disorder]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004906 Increasing cholesterol level 'Increasing cholesterol level' SubClassOf 'increasing lipid' 'Increasing cholesterol level' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'Increasing cholesterol level' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing cholesterol level' SubClassOf 'GJA1 (human) [hepatocarcinogenesis]' 'Increasing cholesterol level' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004907 Increasing cholesterol level [mitochondrial disorder] 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'Increasing cholesterol level' 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing triol level [mitochondrial disorder]' 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'aflatoxin B1' 'Increasing cholesterol level [mitochondrial disorder]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004908 Increasing triol level [mitochondrial disorder] 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'Increasing triol level' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has output' only 'triol' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has result' some 'DNA replication [hepatocarcinogenesis]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'diacylglycerol acumulation' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'styrene oxide [hepatocarcinogenesis]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'Negative regulation of sphingolipid metabolic process' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'aflatoxin metabolic process' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'diacylglycerol accumulation [mitochondrial disorder]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has output' some 'cisplatin resistance' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'Negative regulation of sphingolipid metabolic process [hepatocarcinogenesis]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'drug resistance' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has input' some 'Increasing cholesterol level [mitochondrial disorder]' 'Increasing triol level [mitochondrial disorder]' SubClassOf 'has agent' some 'ceramide accumulation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004909 cisplatin resistance 'cisplatin resistance' SubClassOf 'drug resistance' 'cisplatin resistance' SubClassOf 'aflatoxin B1 exo-8,9-epoxide' 'cisplatin resistance' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004902 GJB1 (human) [hepatocarcinogenesis] 'GJB1 (human) [hepatocarcinogenesis]' SubClassOf 'GJB1 (mol)' 'GJB1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'GJB1 (human) [hepatocarcinogenesis]' SubClassOf 'mutation' http://purl.obolibrary.org/obo/TXPO_0004903 Src (human) [hepatocarcinogenesis] 'Src (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Src (human) [hepatocarcinogenesis]' SubClassOf 'Src (mol)' 'Src (human) [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'actin cytoskeleton organization and biogenesis' 'Src (human) [hepatocarcinogenesis]' SubClassOf 'negative regulation process' http://purl.obolibrary.org/obo/TXPO_0004904 negative regulation of connexin signaling [hepatocarcinogenesis] 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'connexin signaling (primitive)' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'GJB1 (human) [hepatocarcinogenesis]' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'GJA1 (human) [hepatocarcinogenesis]' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'Connexin signal transduction pathway' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of gap-junctional intercellular communication [hepatocarcinogenesis]' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'negative regulation of connexin signaling' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'has output' some 'ketone body' 'negative regulation of connexin signaling [hepatocarcinogenesis]' SubClassOf 'generating substance' http://purl.obolibrary.org/obo/TXPO_0004905 GJA1 (human) [hepatocarcinogenesis] 'GJA1 (human) [hepatocarcinogenesis]' SubClassOf 'GJA1 (mol)' 'GJA1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'GJA1 (human) [hepatocarcinogenesis]' SubClassOf 'decreasing quantity' http://purl.obolibrary.org/obo/TXPO_0004900 gemfibrozil [hepatocarcinogenesis] 'gemfibrozil [hepatocarcinogenesis]' SubClassOf 'gemfibrozil' 'gemfibrozil [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'gemfibrozil [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'gemfibrozil [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'gemfibrozil [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004901 Connexin signaling (primitive) [hepatocarcinogenesis] 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Src (human) [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'connexin signaling (primitive)' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Connexin signal transduction pathway' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'GJB1 (human) [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'tumor cell invasion [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'Increasing PPARA level' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'DNA replication [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'NDUFV1 inactivation' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'gemfibrozil [hepatocarcinogenesis]' 'Connexin signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has part' some 'Increasing PROM1 level' http://purl.obolibrary.org/obo/TXPO_0001043 lipid homeostasis imbalance (moderate) [Lipidosis] 'lipid homeostasis imbalance (moderate) [Lipidosis]' SubClassOf 'has state' some 'toxicological imbalance ML' http://purl.obolibrary.org/obo/TXPO_0001040 lipid metabolism imbalance (moderate) [Lipidosis] 'lipid metabolism imbalance (moderate) [Lipidosis]' SubClassOf 'has result' some 'lipid homeostasis imbalance (mild) [Lipidosis]' 'lipid metabolism imbalance (moderate) [Lipidosis]' SubClassOf 'has result' some 'lipid homeostasis imbalance (moderate) [Lipidosis]' http://purl.obolibrary.org/obo/TXPO_0001038 lipid homeostasis imbalance (severe) [Lipidosis] 'lipid homeostasis imbalance (severe) [Lipidosis]' SubClassOf 'has state' some ('toxicological imbalance VL (excess biodefense function)' or 'toxicological imbalance VL (toxic action)') http://purl.obolibrary.org/obo/TXPO_0004957 MTAP (human) [hepatocarcinogenesis] 'MTAP (human) [hepatocarcinogenesis]' SubClassOf 'MTAP (mol)' 'MTAP (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'MTAP (human) [hepatocarcinogenesis]' SubClassOf 'MTAP (rat) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004958 MTAP (rat) [hepatocarcinogenesis] 'MTAP (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'MTAP (rat) [hepatocarcinogenesis]' SubClassOf 'MTAP (mol)' 'MTAP (rat) [hepatocarcinogenesis]' SubClassOf 'decreasing sensitivity' http://purl.obolibrary.org/obo/TXPO_0004959 Monuron [hepatocarcinogenesis] 'Monuron [hepatocarcinogenesis]' SubClassOf 'Monuron' 'Monuron [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'Monuron [hepatocarcinogenesis]' SubClassOf 'has input' some 'diacylglycerol' 'Monuron [hepatocarcinogenesis]' SubClassOf 'lipid storage' http://purl.obolibrary.org/obo/TXPO_0004953 MMP2(canonical) [hepatocarcinogenesis] 'MMP2(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'MMP2(canonical) [hepatocarcinogenesis]' SubClassOf 'MMP2 (mol)' 'MMP2(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'MMP2(canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005087 http://purl.obolibrary.org/obo/TXPO_0004954 MMP9(canonical) [hepatocarcinogenesis] 'MMP9(canonical) [hepatocarcinogenesis]' SubClassOf 'MMP9 (mol)' 'MMP9(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'MMP9(canonical) [hepatocarcinogenesis]' SubClassOf 'increasing lipid' http://purl.obolibrary.org/obo/TXPO_0004955 Negative regulation of methionine metabolic process 'Negative regulation of methionine metabolic process' SubClassOf 'negative regulation process' 'Negative regulation of methionine metabolic process' SubClassOf 'negatively regulates' some 'methionine metabolic process' 'Negative regulation of methionine metabolic process' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Negative regulation of methionine metabolic process' SubClassOf 'MMP9(canonical) [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process' SubClassOf 'mitochondrial disorder dependent process' 'Negative regulation of methionine metabolic process' SubClassOf 'has result' some 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004956 Negative regulation of methionine metabolic process [hepatocarcinogenesis] 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has participant' some 'MTAP (human) [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL4 [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'Negative regulation of methionine metabolic process' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'methionine metabolic process' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has participant' some 'MTAP (rat) [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'hypoxia [hepatocarcinogenesis]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has output' only 'triol' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' 'Negative regulation of methionine metabolic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004950 Increasing mitochondrial membrane potential 'Increasing mitochondrial membrane potential' SubClassOf 'Increasing membrane potential' 'Increasing mitochondrial membrane potential' SubClassOf 'occurs in' only 'mitochondrial membrane' 'Increasing mitochondrial membrane potential' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Increasing mitochondrial membrane potential' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005088 http://purl.obolibrary.org/obo/TXPO_0004951 Increasing membrane potential 'Increasing membrane potential' SubClassOf 'manifests phenotype' some http://purl.obolibrary.org/obo/TXPO_0004985 'Increasing membrane potential' SubClassOf 'changing membrane potential' 'Increasing membrane potential' SubClassOf 'Src (mol)' 'Increasing membrane potential' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004952 metalloprotease activation 'metalloprotease activation' SubClassOf 'activating' 'metalloprotease activation' SubClassOf 'negatively regulates' some 'formation of DNA adducts [hepatocarcinogenesis]' 'metalloprotease activation' SubClassOf 'has result' some 'FAS signaling [mitochondrial disorder]' 'metalloprotease activation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'metalloprotease activation' SubClassOf 'liver carcinogenesis dependent process' 'metalloprotease activation' SubClassOf 'negatively regulates' some 'formation of DNA adducts' 'metalloprotease activation' SubClassOf 'has participant' some 'Increasing mitochondrial membrane potential' 'metalloprotease activation' SubClassOf 'has participant' some 'MMP2(canonical) [hepatocarcinogenesis]' 'metalloprotease activation' SubClassOf 'malondialdehyde [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004946 negative regulation of phosphorylation 'negative regulation of phosphorylation' SubClassOf 'negatively regulates' some 'phosphorylation' 'negative regulation of phosphorylation' SubClassOf 'negative regulation process' 'negative regulation of phosphorylation' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'negative regulation of phosphorylation' SubClassOf 'mitochondrial disorder dependent process' 'negative regulation of phosphorylation' SubClassOf 'has output' some 'ketone body' 'negative regulation of phosphorylation' SubClassOf 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation' 'negative regulation of phosphorylation' SubClassOf 'has result' some 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004947 mitochondrial respiratory chain complex I subunit phosphorylation 'mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'has input' some 'mitochondrial respiratory chain complex I subunit' 'mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'phosphorylation' 'mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'changing state' http://purl.obolibrary.org/obo/TXPO_0004948 dysregulation of mitochondrion organization 'dysregulation of mitochondrion organization' SubClassOf 'malfunctioning of controlling' 'dysregulation of mitochondrion organization' SubClassOf not ('is entity in organism' some 'homo sapiens') 'dysregulation of mitochondrion organization' SubClassOf 'CDK1 inactivation' 'dysregulation of mitochondrion organization' SubClassOf 'is entity in organism' some 'rodentia' 'dysregulation of mitochondrion organization' SubClassOf 'gemfibrozil' http://purl.obolibrary.org/obo/TXPO_0004949 mitochondrial membrane morphology changes 'mitochondrial membrane morphology changes' SubClassOf 'mitochondria morphology change' 'mitochondrial membrane morphology changes' SubClassOf 'formation of DNA adducts [hepatocarcinogenesis]' 'mitochondrial membrane morphology changes' SubClassOf 'has participant' some 'Increasing membrane potential' 'mitochondrial membrane morphology changes' SubClassOf 'has result' some 'pentadecafluorooctanoic acid' 'mitochondrial membrane morphology changes' SubClassOf 'has pathway' some 'formation of DNA adducts' 'mitochondrial membrane morphology changes' SubClassOf 'liver carcinogenesis dependent process' 'mitochondrial membrane morphology changes' SubClassOf 'has participant' some 'Increasing mitochondrial membrane potential' 'mitochondrial membrane morphology changes' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004942 Increase in mitochondrial calcium level [mitochondrial disorder] 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'Increase in mitochondrial calcium level' 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'has result' some 'positive regulation of mitochondrial membrane permeability [Mitochondrial disorder]' 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'hyperfunction of' some 'gluconeogenesis' 'Increase in mitochondrial calcium level [mitochondrial disorder]' SubClassOf 'hyperfunction of biosynthesis' http://purl.obolibrary.org/obo/TXPO_0004943 mitochondrial cholesterol storage 'mitochondrial cholesterol storage' SubClassOf 'occurs in' only 'lysosome' 'mitochondrial cholesterol storage' SubClassOf 'cholesterol storage' 'mitochondrial cholesterol storage' SubClassOf 'decreasing quantity' http://purl.obolibrary.org/obo/TXPO_0004944 mitochondrial cholesterol storage [mitochondrial disorder] 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'redox changes [mitochondrial disorder]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of glutathione transport into mitochondria' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'mitochondrial cholesterol storage' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'TNF signaling [mitochondrial disorder]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'JNK signaling (primitive) [mitochondrial disorder]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'occurs in' only 'mitochondrion' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'has result' some 'FAS signaling [mitochondrial disorder]' 'mitochondrial cholesterol storage [mitochondrial disorder]' SubClassOf 'negative regulation of transport' http://purl.obolibrary.org/obo/TXPO_0004945 Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'negative regulation of phosphorylation' 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'negatively regulates' some 'mitochondrial respiratory chain complex I subunit phosphorylation' 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004940 Hypofunction of mitochondrial repair 'Hypofunction of mitochondrial repair' SubClassOf 'hypofunctioning' 'Hypofunction of mitochondrial repair' SubClassOf 'occurs in' only 'mitochondrion' 'Hypofunction of mitochondrial repair' SubClassOf 'decreasing quantity' http://purl.obolibrary.org/obo/TXPO_0004941 Increase in mitochondrial calcium level 'Increase in mitochondrial calcium level' SubClassOf 'increasing calcium ion concentration in blood' 'Increase in mitochondrial calcium level' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increase in mitochondrial calcium level' SubClassOf 'mitochondrial disorder dependent process' 'Increase in mitochondrial calcium level' SubClassOf 'Hypofunction of mitochondrial repair' 'Increase in mitochondrial calcium level' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004939 long-chain fatty acid import into mitochondria [mitochondrial disorder] 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'PPARalpha activation [Mitochondrial disorder]' 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has agent' some 'CPT1(canonical) [mitochondrial disorder]' 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing mitochondrial membrane potential [Mitochondrial disorder]' 'long-chain fatty acid import into mitochondria [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004935 glutathione transport from cytoplasm into mitochondria 'glutathione transport from cytoplasm into mitochondria' SubClassOf 'glutathione transport' 'glutathione transport from cytoplasm into mitochondria' SubClassOf 'has target start location' some 'cytoplasm' 'glutathione transport from cytoplasm into mitochondria' SubClassOf 'has target end location' only 'mitochondrion' 'glutathione transport from cytoplasm into mitochondria' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004936 Negative regulation of glutathione transport into mitochondria 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'Negative regulation of glutathione transport' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'glutathione transport from cytoplasm into mitochondria' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'has result' some 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004937 Negative regulation of glutathione transport into mitochondria 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'Negative regulation of glutathione transport into mitochondria' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'has result' some 'decreasing glutathione level [mitochondrial disorder]' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'glucose homeostasis imbalance' 'Negative regulation of glutathione transport into mitochondria' SubClassOf 'has result' some 'Malfunctioning of insulin signaling [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004938 long-chain fatty acid import into mitochondria 'long-chain fatty acid import into mitochondria' SubClassOf 'long-chain fatty acid transport' 'long-chain fatty acid import into mitochondria' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004931 malondialdehyde [mitochondrial disorder] 'malondialdehyde [mitochondrial disorder]' SubClassOf 'mitochondria disorder dependent chemical compound' 'malondialdehyde [mitochondrial disorder]' SubClassOf 'malondialdehyde' 'malondialdehyde [mitochondrial disorder]' SubClassOf 'has input' some 'cardiolipin' 'malondialdehyde [mitochondrial disorder]' SubClassOf 'disruption of ER-mitochondria contact sites' http://purl.obolibrary.org/obo/TXPO_0004932 disruption of ER-mitochondria contact sites 'disruption of ER-mitochondria contact sites' SubClassOf 'negative regulation process' 'disruption of ER-mitochondria contact sites' SubClassOf 'negatively regulates' some 'inflammatory response' 'disruption of ER-mitochondria contact sites' SubClassOf 'lipoperoxidation' http://purl.obolibrary.org/obo/TXPO_0004933 Disruption of ER-mitochondria contact sites [mitochondrial disorder] 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' SubClassOf 'disruption of ER-mitochondria contact sites' 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' SubClassOf 'has result' some 'glucose homeostasis imbalance [mitochondrial disorder]' 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' SubClassOf 'organic molecular entity' http://purl.obolibrary.org/obo/TXPO_0004934 increasing mtDNA level 'increasing mtDNA level' SubClassOf 'increasing quantity' 'increasing mtDNA level' SubClassOf 'Disruption of ER-mitochondria contact sites [mitochondrial disorder]' 'increasing mtDNA level' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004930 macrophage migration [mitochondrial disorder] 'macrophage migration [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'macrophage migration [mitochondrial disorder]' SubClassOf 'macrophage migration' 'macrophage migration [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'macrophage migration [mitochondrial disorder]' SubClassOf 'has result' some 'JNK signaling (primitive) [mitochondrial disorder]' 'macrophage migration [mitochondrial disorder]' SubClassOf 'TFAM (mol)' 'macrophage migration [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004928 Increasing uric acid level [mitochondrial disorder] 'Increasing uric acid level [mitochondrial disorder]' SubClassOf 'has output' only 'uric acid' 'Increasing uric acid level [mitochondrial disorder]' SubClassOf 'Increasing uric acid level' 'Increasing uric acid level [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Increasing uric acid level [mitochondrial disorder]' SubClassOf 'autophagy' http://purl.obolibrary.org/obo/TXPO_0004929 nagative regulation of mitophagy 'nagative regulation of mitophagy' SubClassOf 'regulation of mitophagy' 'nagative regulation of mitophagy' SubClassOf 'positively regulates' some 'mitohagy' 'nagative regulation of mitophagy' SubClassOf 'autophagy' 'nagative regulation of mitophagy' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'nagative regulation of mitophagy' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'nagative regulation of mitophagy' SubClassOf 'has participant' some 'macrophage migration [mitochondrial disorder]' 'nagative regulation of mitophagy' SubClassOf 'has participant' some 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'nagative regulation of mitophagy' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004924 fialuridine 'fialuridine' SubClassOf 'organic molecular entity' 'fialuridine' SubClassOf 'has role' some 'antiviral drug' 'fialuridine' SubClassOf 'CDK1 inactivation' 'fialuridine' SubClassOf 'alcohol' http://purl.obolibrary.org/obo/TXPO_0004925 Increasing fructose level 'Increasing fructose level' SubClassOf 'has output' only 'fructose' 'Increasing fructose level' SubClassOf 'increasing quantity' 'Increasing fructose level' SubClassOf 'NLRP3 (mol)' 'Increasing fructose level' SubClassOf 'lipidosis dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0004926 Increasing fructose level [mitochondrial disorder] 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'DNA damage [Mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of mitochondrial fatty acid beta-oxidation [Mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has output' only 'fructose' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'lipid biosynthetic process [mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'Hypofunction of mitochondrial repair [mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'Increasing fructose level' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing uric acid level [mitochondrial disorder]' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'dysfunctioning of' some 'cholesterol biosynthetic process' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing cholesterol concentration in blood' 'Increasing fructose level [mitochondrial disorder]' SubClassOf 'hypofunction of lipid biosynthesis' http://purl.obolibrary.org/obo/TXPO_0004927 Hypofunction of mitochondrial repair [mitochondrial disorder] 'Hypofunction of mitochondrial repair [mitochondrial disorder]' SubClassOf 'Hypofunction of mitochondrial repair' 'Hypofunction of mitochondrial repair [mitochondrial disorder]' SubClassOf 'occurs in' only 'mitochondrion' 'Hypofunction of mitochondrial repair [mitochondrial disorder]' SubClassOf 'Increasing fructose level [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004920 Increasing triol level 'Increasing triol level' SubClassOf 'has output' only 'triol' 'Increasing triol level' SubClassOf 'increasing quantity' 'Increasing triol level' SubClassOf 'positive regulation process' 'Increasing triol level' SubClassOf 'positively regulates' some 'arachidonic acid metabolism' http://purl.obolibrary.org/obo/TXPO_0004921 Methapyrilene hydrochloride [hepatocarcinogenesis] 'Methapyrilene hydrochloride [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'Methapyrilene hydrochloride [hepatocarcinogenesis]' SubClassOf 'Methapyrilene hydrochloride' 'Methapyrilene hydrochloride [hepatocarcinogenesis]' SubClassOf 'decreasing quantity' 'Methapyrilene hydrochloride [hepatocarcinogenesis]' SubClassOf 'has input' some 'arachidonic acid' http://purl.obolibrary.org/obo/TXPO_0004922 panadiplon 'panadiplon' SubClassOf 'has role' some 'anxiolytic drug' 'panadiplon' SubClassOf 'organic molecular entity' 'panadiplon' SubClassOf 'CDK1 inactivation' 'panadiplon' SubClassOf 'aristolochic acid' http://purl.obolibrary.org/obo/TXPO_0004923 pyrethrins [hepatocarcinogenesis] 'pyrethrins [hepatocarcinogenesis]' SubClassOf not ('is entity in organism' some 'homo sapiens') 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'rodentia' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'pyrethrins' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'has result' some 'IL-6(human)[hepatocarcinogenesis]' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'has input' some 'fialuridine' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'has result' some 'fumonisin B1 [hepatocarcinogenesis]' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'alcohol intake' 'pyrethrins [hepatocarcinogenesis]' SubClassOf 'has result' some 'CCND1 (human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004917 sorafenib resistance (process) 'sorafenib resistance (process)' SubClassOf 'drug resistance' 'sorafenib resistance (process)' SubClassOf 'PPARGC1A (mol)' 'sorafenib resistance (process)' SubClassOf 'BCL2 (mol)' 'sorafenib resistance (process)' SubClassOf 'has related human gene' some 'BCL2' http://purl.obolibrary.org/obo/TXPO_0004918 Telomerase reverse transcriptase gene mutation 'Telomerase reverse transcriptase gene mutation' SubClassOf 'mutation' 'Telomerase reverse transcriptase gene mutation' SubClassOf 'PPARGC1A (mol)' 'Telomerase reverse transcriptase gene mutation' SubClassOf 'Cyclin D1 (mol)' 'Telomerase reverse transcriptase gene mutation' SubClassOf 'has related human gene' some 'CCND1' http://purl.obolibrary.org/obo/TXPO_0004919 TERT (canonical) [hepatocarcinogenesis] 'TERT (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'TERT (canonical) [hepatocarcinogenesis]' SubClassOf 'TERT (mol)' 'TERT (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'TERT (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TERT (canonical) [hepatocarcinogenesis]' SubClassOf 'tumor cell survial' http://purl.obolibrary.org/obo/TXPO_0004997 Increasing long-chain free fatty acid level 'Increasing long-chain free fatty acid level' SubClassOf 'increasing quantity' 'Increasing long-chain free fatty acid level' SubClassOf 'malfunctioning of controlling' http://purl.obolibrary.org/obo/TXPO_0004998 Increasing long-chain free fatty acid level [mitochondrial disorder] 'Increasing long-chain free fatty acid level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing long-chain free fatty acid level [mitochondrial disorder]' SubClassOf 'Increasing long-chain free fatty acid level' 'Increasing long-chain free fatty acid level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing long-chain free fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'Increasing long-chain free fatty acid level [mitochondrial disorder]' SubClassOf 'Increasing glucagon level [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004999 increasing saturated fatty acid level 'increasing saturated fatty acid level' SubClassOf 'increasing lipid' 'increasing saturated fatty acid level' SubClassOf 'Increasing saturated fatty acid level [mitochondrial disorder]' 'increasing saturated fatty acid level' SubClassOf 'occurs in' only 'mitochondrial membrane' http://purl.obolibrary.org/obo/TXPO_0004993 iron metabolic dysfunction 'iron metabolic dysfunction' SubClassOf 'metabolic dysfunction' 'iron metabolic dysfunction' SubClassOf 'negatively regulates' some 'Increasing iron uptake level' 'iron metabolic dysfunction' SubClassOf 'iron metabolic dysfunction [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004994 iron metabolic dysfunction [hepatocarcinogenesis] 'iron metabolic dysfunction [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'iron metabolic dysfunction [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'iron metabolic dysfunction [hepatocarcinogenesis]' SubClassOf 'iron metabolic dysfunction' 'iron metabolic dysfunction [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'phosphorylation' 'iron metabolic dysfunction [hepatocarcinogenesis]' SubClassOf 'negative regulation process' http://purl.obolibrary.org/obo/TXPO_0004995 Increasing iron uptake level 'Increasing iron uptake level' SubClassOf 'increasing quantity' 'Increasing iron uptake level' SubClassOf 'phosphorylation' 'Increasing iron uptake level' SubClassOf 'has input' some 'mitochondrial respiratory chain complex I subunit' http://purl.obolibrary.org/obo/TXPO_0004996 hypofunction of heme biosynthesis 'hypofunction of heme biosynthesis' SubClassOf 'dysfunctioning of' some 'heme biosynthetic process' 'hypofunction of heme biosynthesis' SubClassOf 'hypofunction of biosynthesis' 'hypofunction of heme biosynthesis' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'hypofunction of heme biosynthesis' SubClassOf 'has result' some 'FGF21(canonical) [mitochondrial disorder]' 'hypofunction of heme biosynthesis' SubClassOf 'has result' some 'TGF-alpha signaling (primitive)' 'hypofunction of heme biosynthesis' SubClassOf 'liver carcinogenesis dependent process' 'hypofunction of heme biosynthesis' SubClassOf 'mitochondrial dysfunction' http://purl.obolibrary.org/obo/TXPO_0004990 neovascularization 'neovascularization' SubClassOf 'biological structure formation' 'neovascularization' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'neovascularization' SubClassOf 'endothelial progenitor cell mobilization' 'neovascularization' SubClassOf 'mitochondrial disorder dependent process' 'neovascularization' SubClassOf 'has result' some 'positive regulation of mitochondrial membrane permeability [Mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004991 enzyme production 'enzyme production' SubClassOf 'protein production' 'enzyme production' SubClassOf 'cholesterol storage' 'enzyme production' SubClassOf 'occurs in' only 'lysosome' http://purl.obolibrary.org/obo/TXPO_0004992 TP53(canonical) [hepatocarcinogenesis] 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'p53 (mol)' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'occurs in' only 'mitochondrion' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'enzyme production' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'JNK signaling (primitive) [mitochondrial disorder]' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'beta-catenin signal (primitive)' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'redox changes [mitochondrial disorder]' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hypofunction of mitochondrial repair [mitochondrial disorder]' 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some http://purl.obolibrary.org/obo/TXPO_0004985 'TP53(canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'GADD45G (mol)' http://purl.obolibrary.org/obo/TXPO_0004986 Increasing cholesterol concentration in blood 'Increasing cholesterol concentration in blood' SubClassOf 'increasing lipid concentration' 'Increasing cholesterol concentration in blood' SubClassOf 'long-chain fatty acid transport' http://purl.obolibrary.org/obo/TXPO_0004987 increasing lipid concentration 'increasing lipid concentration' SubClassOf 'increasing concentration' 'increasing lipid concentration' SubClassOf 'Increasing cholesterol concentration in blood' 'increasing lipid concentration' SubClassOf 'has agent' some 'CXCR3 signaling [hepatocarcinogenesis]' 'increasing lipid concentration' SubClassOf 'mitochondrial disorder dependent process' 'increasing lipid concentration' SubClassOf 'has result' some 'PPARalpha activation [Mitochondrial disorder]' 'increasing lipid concentration' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004988 Increasing cholesterol concentration in blood [mitochondrial disorder] 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'Increasing cholesterol concentration in blood' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing mitochondrial membrane potential [Mitochondrial disorder]' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'occurs in' only 'mitochondrion' 'Increasing cholesterol concentration in blood [mitochondrial disorder]' SubClassOf 'hypofunctioning' http://purl.obolibrary.org/obo/TXPO_0004989 endothelial progenitor cell mobilization 'endothelial progenitor cell mobilization' SubClassOf 'cell migration' 'endothelial progenitor cell mobilization' SubClassOf 'increasing calcium ion concentration in blood' http://purl.obolibrary.org/obo/TXPO_0004982 Increasing lipid [hepatocarcinogenesis] 'Increasing lipid [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing lipid [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing lipid [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing SPTLC3 level [hepatocarcinogenesis]' 'Increasing lipid [hepatocarcinogenesis]' SubClassOf 'increasing lipid' 'Increasing lipid [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004983 increasing lipid concentration [mitochondrial disorder] 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'increasing lipid concentration' 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'glutathione transport' 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'has target end location' only 'mitochondrion' 'increasing lipid concentration [mitochondrial disorder]' SubClassOf 'has target start location' some 'cytoplasm' http://purl.obolibrary.org/obo/TXPO_0004984 tumor malignancy alteration 'tumor malignancy alteration' SubClassOf 'changing quality' 'tumor malignancy alteration' SubClassOf 'mitochondrial cholesterol storage [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004985 http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'membrane potential' http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'electric potential attribute' and ('has attribute value' some 'large (value)') http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'tumor malignancy alteration' http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'has result' some 'TLR4 signaling pathway [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004985 SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004980 nodule formation [hepatocarcinogenesis] 'nodule formation [hepatocarcinogenesis]' SubClassOf 'nodule formation' 'nodule formation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'nodule formation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'nodule formation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'nodule formation [hepatocarcinogenesis]' SubClassOf 'negative regulation process' 'nodule formation [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'inflammatory response' http://purl.obolibrary.org/obo/TXPO_0004981 hepatocyte regeneration 肝細胞再生 '肝細胞再生' SubClassOf 'tissue regeneration' '肝細胞再生' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' '肝細胞再生' SubClassOf 'has result' some 'Negative regulation of glutathione transport into mitochondria' '肝細胞再生' SubClassOf 'mitochondrial disorder dependent process' '肝細胞再生' SubClassOf 'nodule formation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004979 increasing blood glucose level [mitochondrial disorder] 'increasing blood glucose level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing blood glucose level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing blood glucose level [mitochondrial disorder]' SubClassOf 'increasing blood glucose level' 'increasing blood glucose level [mitochondrial disorder]' SubClassOf 'malondialdehyde' 'increasing blood glucose level [mitochondrial disorder]' SubClassOf 'mitochondria disorder dependent chemical compound' http://purl.obolibrary.org/obo/TXPO_0004975 increasing damaged mitochondria 'increasing damaged mitochondria' SubClassOf 'increasing quantity' 'increasing damaged mitochondria' SubClassOf 'occurs in' only 'mitochondrion' 'increasing damaged mitochondria' SubClassOf 'Increasing cholesterol concentration in blood [mitochondrial disorder]' 'increasing damaged mitochondria' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing damaged mitochondria' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004976 release of inflammatory DAMPs [mitochondrial disorder] 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'has result' some 'TLR9 signaling [Mitochondrial disorder]' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'release of inflammatory DAMPs' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'occurs in' some 'mitochondrion' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to ER stress [mitochondrial disorder]' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'has output' only 'uric acid' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'FZD5 (mol)' 'release of inflammatory DAMPs [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004977 negative regulation of ROS formation [hepatocarcinogenesis] 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'reactive oxygen species biosynthetic process' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'negative regulation of ROS formation' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'has result' some 'PMAIP1 inactivation [hepatocarcinogenesis]' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'positively regulates' some 'mitohagy' 'negative regulation of ROS formation [hepatocarcinogenesis]' SubClassOf 'regulation of mitophagy' http://purl.obolibrary.org/obo/TXPO_0004978 malfunctioning of cytokinesis 'malfunctioning of cytokinesis' SubClassOf 'malfunctioning process' 'malfunctioning of cytokinesis' SubClassOf 'mitochondrial disorder dependent process' 'malfunctioning of cytokinesis' SubClassOf 'macrophage migration' 'malfunctioning of cytokinesis' SubClassOf 'has result' some 'JNK signaling (primitive) [mitochondrial disorder]' 'malfunctioning of cytokinesis' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004971 4-hydroxynonenal [mitochondrial disorder] '4-hydroxynonenal [mitochondrial disorder]' SubClassOf '4-hydroxynonenal' '4-hydroxynonenal [mitochondrial disorder]' SubClassOf 'mitochondria disorder dependent chemical compound' '4-hydroxynonenal [mitochondrial disorder]' SubClassOf 'pyrethrins' '4-hydroxynonenal [mitochondrial disorder]' SubClassOf 'CDK1 inactivation' '4-hydroxynonenal [mitochondrial disorder]' SubClassOf not ('is entity in organism' some 'homo sapiens') '4-hydroxynonenal [mitochondrial disorder]' SubClassOf 'is entity in organism' some 'rodentia' http://purl.obolibrary.org/obo/TXPO_0004972 response to endoplasmic reticulum stress [hepatocarcinogenesis] 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'has part' some 'Grp78 signaling (primitive) [hepatocarcinogenesis]' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'response to endoplasmic reticulum stress' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'has part' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'has role' some 'antiviral drug' 'response to endoplasmic reticulum stress [hepatocarcinogenesis]' SubClassOf 'organic molecular entity' http://purl.obolibrary.org/obo/TXPO_0004973 Increasing uric acid level 'Increasing uric acid level' SubClassOf 'has output' only 'uric acid' 'Increasing uric acid level' SubClassOf 'has output' only 'fructose' http://purl.obolibrary.org/obo/TXPO_0004974 negative regulation of antioxidant enzyme activation 'negative regulation of antioxidant enzyme activation' SubClassOf 'negative regulation of enzyme activation' 'negative regulation of antioxidant enzyme activation' SubClassOf 'Increasing uric acid level' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has output' only 'fructose' 'negative regulation of antioxidant enzyme activation' SubClassOf 'mitochondrial disorder dependent process' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'DNA damage [Mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'release of inflammatory DAMPs [mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'increasing damaged mitochondria' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'hypofunction of mitochondrial fatty acid beta-oxidation [Mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'lipid biosynthetic process [mitochondrial disorder]' 'negative regulation of antioxidant enzyme activation' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004970 reactive aldehyde [mitochondrial disorder] 'reactive aldehyde [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'reactive aldehyde [mitochondrial disorder]' SubClassOf 'reactive aldehyde' 'reactive aldehyde [mitochondrial disorder]' SubClassOf 'organic molecular entity' 'reactive aldehyde [mitochondrial disorder]' SubClassOf 'has role' some 'anxiolytic drug' http://purl.obolibrary.org/obo/TXPO_0004968 hypoxia [hepatocarcinogenesis] 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has result' some 'PI3K signaling (primitive) [hepatocarcinogenesis]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 inactivation [hepatocarcinogenesis]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has result' some 'YAP signaling (primitive) [hepatocarcinogenesis]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has result' some 'WNT signaling (primitive) [hepatocarcinogenesis]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'hypoxia' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has result' some 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'increasing quantity' 'hypoxia [hepatocarcinogenesis]' SubClassOf 'has output' only 'triol' http://purl.obolibrary.org/obo/TXPO_0004969 increasing production amount of reactive aldehyde 'increasing production amount of reactive aldehyde' SubClassOf 'increasing quantity' 'increasing production amount of reactive aldehyde' SubClassOf 'CDK1 inactivation' 'increasing production amount of reactive aldehyde' SubClassOf 'Methapyrilene hydrochloride' http://purl.obolibrary.org/obo/TXPO_0004964 increasing leptin level [mitochondrial disorder] 'increasing leptin level [mitochondrial disorder]' SubClassOf 'has result' some 'PPARalpha activation [Mitochondrial disorder]' 'increasing leptin level [mitochondrial disorder]' SubClassOf 'increasing leptin level' 'increasing leptin level [mitochondrial disorder]' SubClassOf 'ceramide acumulation' 'increasing leptin level [mitochondrial disorder]' SubClassOf 'has result' some 'PTPRD gene promoter methylation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004965 tumor malignancy alteration [hepatocarcinogenesis] 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'tumor malignancy alteration' 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'has part' some 'metastasis [hepatocarcinogenesis]' 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'has part' some 'tumor cell invasion [hepatocarcinogenesis]' 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'tumor malignancy alteration [hepatocarcinogenesis]' SubClassOf 'MTAP (rat) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004966 malfunctioning of centrosome duplication 'malfunctioning of centrosome duplication' SubClassOf 'malfunctioning process' 'malfunctioning of centrosome duplication' SubClassOf 'mutation' http://purl.obolibrary.org/obo/TXPO_0004967 HIF1A(canonical) [hepatocarcinogenesis] 'HIF1A(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'HIF1A(canonical) [hepatocarcinogenesis]' SubClassOf 'HIF1A (mol)' 'HIF1A(canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'HIF1A(canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005133 http://purl.obolibrary.org/obo/TXPO_0004960 phospholipid peroxidation [mitochondrial disorder] 'phospholipid peroxidation [mitochondrial disorder]' SubClassOf 'phospholipid peroxidation' 'phospholipid peroxidation [mitochondrial disorder]' SubClassOf 'has result' some 'positive regulation of mitochondrial membrane permeability [Mitochondrial disorder]' 'phospholipid peroxidation [mitochondrial disorder]' SubClassOf 'Monuron [hepatocarcinogenesis]' 'phospholipid peroxidation [mitochondrial disorder]' SubClassOf 'has result' some 'PTPRD gene promoter methylation [hepatocarcinogenesis]' 'phospholipid peroxidation [mitochondrial disorder]' SubClassOf 'has input' some 'diacylglycerol' http://purl.obolibrary.org/obo/TXPO_0004961 lipoperoxidation [hepatocarcinogenesis] 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'fumonisin B1 [hepatocarcinogenesis]' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'has output' some 'malondialdehyde [hepatocarcinogenesis]' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'lipoperoxidation' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'lipoperoxidation [hepatocarcinogenesis]' SubClassOf 'styrene oxide' http://purl.obolibrary.org/obo/TXPO_0004962 redox change 'redox change' SubClassOf 'changing state' 'redox change' SubClassOf 'negative regulation process' 'redox change' SubClassOf 'negatively regulates' some 'sphingolipid metabolic process' http://purl.obolibrary.org/obo/TXPO_0004963 increasing leptin level 'increasing leptin level' SubClassOf 'increasing quantity' 'increasing leptin level' SubClassOf 'has result' some 'Increasing ACSL4 level' 'increasing leptin level' SubClassOf 'redox change' 'increasing leptin level' SubClassOf 'has result' some 'ACSL1 (mol)' 'increasing leptin level' SubClassOf 'negatively regulates' some 'sphingolipid metabolic process' 'increasing leptin level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing leptin level' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'increasing leptin level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0001177 Cholesterol homeostasis imbalance [Niemann-Pick C] 'Cholesterol homeostasis imbalance [Niemann-Pick C]' SubClassOf 'has state' some http://purl.obolibrary.org/obo/TXPO_0002327 http://purl.obolibrary.org/obo/TXPO_0002408 PLA2G5 (human)(canonical)[Phospholipidosis] 'PLA2G5 (human)(canonical)[Phospholipidosis]' SubClassOf 'participates in' some 'phosphatidylcholine catabolic process' 'PLA2G5 (human)(canonical)[Phospholipidosis]' SubClassOf 'relateds assay' some 'in vitro assay (human)' http://purl.obolibrary.org/obo/TXPO_0004799 cytolysis [mitochondrial disorder] 'cytolysis [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'cytolysis [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'cytolysis [mitochondrial disorder]' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' 'cytolysis [mitochondrial disorder]' SubClassOf 'occurs in' some 'cell' 'cytolysis [mitochondrial disorder]' SubClassOf 'cytolysis' 'cytolysis [mitochondrial disorder]' SubClassOf 'has result' some 'necrosis [mitochondrial disorder]' 'cytolysis [mitochondrial disorder]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004795 TGF-alpha signaling (primitive) [hepatocarcinogenesis] 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'TGFA (canonical) [hepatocarcinogenesis]' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TGF-alpha signal transduction pathway' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'TGF-alpha signaling (primitive)' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'dysfunctioning of' some 'S-adenosylmethionine biosynthetic process' 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'hypofunction of biosynthesis' http://purl.obolibrary.org/obo/TXPO_0004796 TGFA (canonical) [hepatocarcinogenesis] 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'TGFA (mol)' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'dysfunctioning of' some 'S-adenosylmethionine biosynthetic process' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'TLR4 signaling pathway [mitochondrial disorder]' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'TGF-alpha signaling (primitive) [hepatocarcinogenesis]' 'TGFA (canonical) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004797 TLR4 signaling pathway [mitochondrial disorder] 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'TLR4 signaling pathway' 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of anti-oxidative stress[mitochondrial disorder]' 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'mitochondrial cholesterol storage' 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'has result' some 'glutathione depletion [Mitochondrial disorder]' 'TLR4 signaling pathway [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004798 TLR4 signaling (primitive) 'TLR4 signaling (primitive)' SubClassOf 'has agent' some 'TLR4 (mol)' 'TLR4 signaling (primitive)' SubClassOf 'TLR signaling (primitive)' 'TLR4 signaling (primitive)' SubClassOf 'has pathway' some 'TLR4 signaling pathway' 'TLR4 signaling (primitive)' SubClassOf 'inactivation' 'TLR4 signaling (primitive)' SubClassOf 'has output' some ('cytolysis [mitochondrial disorder]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004791 Hypofunction of TFAM gene expression 'Hypofunction of TFAM gene expression' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'Hypofunction of TFAM gene expression' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Hypofunction of TFAM gene expression' SubClassOf 'mitochondrial disorder dependent process' 'Hypofunction of TFAM gene expression' SubClassOf 'has participant' some 'TFAM (canonical) [mitochondrial disorder]' 'Hypofunction of TFAM gene expression' SubClassOf 'has result' some 'TGF-alpha signal transduction pathway' 'Hypofunction of TFAM gene expression' SubClassOf 'has output' some 'TFAM (canonical) [mitochondrial disorder]' 'Hypofunction of TFAM gene expression' SubClassOf 'liver carcinogenesis dependent process' 'Hypofunction of TFAM gene expression' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004792 TFAM (canonical) [mitochondrial disorder] 'TFAM (canonical) [mitochondrial disorder]' SubClassOf 'TFAM (mol)' 'TFAM (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'TFAM (canonical) [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'TFAM (canonical) [mitochondrial disorder]' SubClassOf 'PVT1' http://purl.obolibrary.org/obo/TXPO_0004793 TGF-alpha signal transduction pathway 'TGF-alpha signal transduction pathway' SubClassOf 'signaling pathway' 'TGF-alpha signal transduction pathway' SubClassOf 'Chlorendic Acid [hepatocarcinogenesis]' 'TGF-alpha signal transduction pathway' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TGF-alpha signal transduction pathway' SubClassOf 'has result' some 'YAP signaling (primitive) [hepatocarcinogenesis]' 'TGF-alpha signal transduction pathway' SubClassOf 'liver carcinogenesis dependent process' 'TGF-alpha signal transduction pathway' SubClassOf 'has input' some 'Increasing glucagon level' http://purl.obolibrary.org/obo/TXPO_0004794 TGF-alpha signaling (primitive) 'TGF-alpha signaling (primitive)' SubClassOf 'has pathway' some 'TGF-alpha signal transduction pathway' 'TGF-alpha signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'TGF-alpha signaling (primitive)' SubClassOf 'has result' some 'Hyperfunction of DNA biosynthesis' 'TGF-alpha signaling (primitive)' SubClassOf 'has participant' some 'DNMT1 (rat) [hepatocarcinogenesis]' 'TGF-alpha signaling (primitive)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TGF-alpha signaling (primitive)' SubClassOf 'liver carcinogenesis dependent process' 'TGF-alpha signaling (primitive)' SubClassOf 'increasing production quantity of ROS' http://purl.obolibrary.org/obo/TXPO_0004790 Hypofunction of TFAM gene expression 'Hypofunction of TFAM gene expression' SubClassOf 'hypofunction of transcription, DNA-templated' 'Hypofunction of TFAM gene expression' SubClassOf 'increasing quantity' 'Hypofunction of TFAM gene expression' SubClassOf 'has output' some 'PVT1' http://purl.obolibrary.org/obo/TXPO_0004788 Hepatic fibrosis [hepatocarcinogenesis] 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'hepatic fibrosis' 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'Hepatic fibrosis [hepatocarcinogenesis]' SubClassOf 'DNA methylation' http://purl.obolibrary.org/obo/TXPO_0004789 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'organic molecular entity' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'liver carcinogenesis dependent process' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'Hepatic fibrosis [hepatocarcinogenesis]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'has result' some 'negative regulation of antioxidant enzyme activation [mitochondrial disorder]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'has input' some 'PTPRD (predicted)(human) [hepatocarcinogenesis]' '1,4-bis[2-(3,5-dichloropyridyloxy)]benzene' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004784 TAZ signaling (primitive) 'TAZ signaling (primitive)' SubClassOf 'has pathway' some 'TAZ signal transduction pathway' 'TAZ signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'TAZ signaling (primitive)' SubClassOf 'has participant' some 'TAZ (mol)' 'TAZ signaling (primitive)' SubClassOf 'SNAI1 (human) [hepatocarcinogenesis]' 'TAZ signaling (primitive)' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004785 TAZ (mol) 'TAZ (mol)' SubClassOf 'molecule' 'TAZ (mol)' SubClassOf 'inactivation' 'TAZ (mol)' SubClassOf 'has output' some ('PTPRD (mol)' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004786 TAZ signaling (primitive) [hepatocarcinogenesis] 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hepatic fibrosis [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'neovascularization [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'TAZ (canonical) [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TAZ signal transduction pathway' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'TAZ signaling (primitive)' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'PTPRD (predicted)(human) [hepatocarcinogenesis]' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'TAZ signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0003456 ASAH1 - inactivated (human)[Phospholipidosis - hypofunctioning of ceramide degradation] 'ASAH1 - inactivated (human)[Phospholipidosis - hypofunctioning of ceramide degradation]' SubClassOf 'has role' some 'inhibitor of insulin resistance' http://purl.obolibrary.org/obo/TXPO_0004787 TAZ (canonical) [hepatocarcinogenesis] 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'TAZ (mol)' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'STAT3 activation' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'HMGB1 (canonical) [mitochondrial disorder]' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'TAZ (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004780 Snail1 signaling (primitive) 'Snail1 signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'Snail1 signaling (primitive)' SubClassOf 'has pathway' some 'Snail1 signal transduction pathway' 'Snail1 signaling (primitive)' SubClassOf 'STAT3 signaling (primitive)' 'Snail1 signaling (primitive)' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004781 Snail1 signal transduction pathway 'Snail1 signal transduction pathway' SubClassOf 'signaling pathway' 'Snail1 signal transduction pathway' SubClassOf 'has output' some 'SNAI1 (human) [hepatocarcinogenesis]' 'Snail1 signal transduction pathway' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004782 SNAI1 (human) [hepatocarcinogenesis] 'SNAI1 (human) [hepatocarcinogenesis]' SubClassOf 'SNAI1 (mol)' 'SNAI1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'SNAI1 (human) [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004783 TAZ signal transduction pathway 'TAZ signal transduction pathway' SubClassOf 'signaling pathway' 'TAZ signal transduction pathway' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'TAZ signal transduction pathway' SubClassOf 'has output' some 'TAZ signaling (primitive)' 'TAZ signal transduction pathway' SubClassOf 'Snail1 signal transduction pathway' 'TAZ signal transduction pathway' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TAZ signal transduction pathway' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004777 STAT3 signal transduction pathway 'STAT3 signal transduction pathway' SubClassOf 'signaling pathway' 'STAT3 signal transduction pathway' SubClassOf 'increasing quantity' 'STAT3 signal transduction pathway' SubClassOf 'has output' some 'STAT3 signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004778 STAT3 signaling (primitive) 'STAT3 signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'STAT3 signaling (primitive)' SubClassOf 'has pathway' some 'STAT3 signal transduction pathway' 'STAT3 signaling (primitive)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004779 STAT3(human) [hepatocarcinogenesis] 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'STAT3 (mol)' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'STAT3 signal transduction pathway' 'STAT3(human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'Snail1 signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004773 SFRP1 - inactive form (human) [hepatocarcinogenesis] 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'SFRP1 (human) [hepatocarcinogenesis]' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ATF4 inactivation' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'SFRP1 (mol)' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has input' some 'Increasing SPTLC3 level' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of EPCR signaling' 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004774 Increasing SPTLC3 level 'Increasing SPTLC3 level' SubClassOf 'increasing quantity' 'Increasing SPTLC3 level' SubClassOf 'has output' some 'SPTLC3 (mol)' 'Increasing SPTLC3 level' SubClassOf 'SFRP1 inactivation [hepatocarcinogenesis]' 'Increasing SPTLC3 level' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004775 Increasing SPTLC3 level [hepatocarcinogenesis] 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'SPTLC3 (mouse) [hepatocarcinogenesis]' 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'Increasing SPTLC3 level' 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Increasing SPTLC3 level [hepatocarcinogenesis]' SubClassOf 'DNA methylation' http://purl.obolibrary.org/obo/TXPO_0004776 SPTLC3 (mouse) [hepatocarcinogenesis] 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'SPTLC3 (mol)' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'has result' some 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'Increasing SPTLC3 level [hepatocarcinogenesis]' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'has input' some 'Increasing SPTLC3 level' 'SPTLC3 (mouse) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'positive regulation of cell cycle [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004770 SFRP1 inactivation 'SFRP1 inactivation' SubClassOf 'has output' some ('SFRP1 (mol)' and ('has quality' some 'inactive')) 'SFRP1 inactivation' SubClassOf 'inactivation' 'SFRP1 inactivation' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'SFRP1 inactivation' SubClassOf 'has quality' some 'active' 'SFRP1 inactivation' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005126 http://purl.obolibrary.org/obo/TXPO_0004771 SFRP1 (mol) 'SFRP1 (mol)' SubClassOf 'molecule' 'SFRP1 (mol)' SubClassOf 'has input' some 'SFRP1 inactivation [hepatocarcinogenesis]' 'SFRP1 (mol)' SubClassOf 'decreasing quantity' http://purl.obolibrary.org/obo/TXPO_0004772 SFRP1 inactivation [hepatocarcinogenesis] 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'SFRP1 inactivation' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has agent' some 'trimeric UHRF1 repression complex (human) [hepatocarcinogenesis]' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'SFRP1 - inactive form (human) [hepatocarcinogenesis]' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'SFRP1 inactivation [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0003435 phospholipid homeostasis imbalance [Phospholipidosis (severe) ] 'phospholipid homeostasis imbalance [Phospholipidosis (severe) ]' SubClassOf 'has state' some ('toxicological imbalance VL (excess biodefense function)' or 'toxicological imbalance VL (toxic action)') http://purl.obolibrary.org/obo/TXPO_0004766 increasing production quantity of ROS [hepatocarcinogenesis] 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'has participant' some '2-acetamidofluorene [hepatocarcinogenesis]' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA damage [hepatocarcinogenesis]' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'increasing production quantity of ROS' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'increasing production quantity of ROS [hepatocarcinogenesis]' SubClassOf 'PPARA (mol)' http://purl.obolibrary.org/obo/TXPO_0004767 hypofunction of S-adenosylmethionine biosynthetic process 'hypofunction of S-adenosylmethionine biosynthetic process' SubClassOf 'dysfunctioning of' some 'S-adenosylmethionine biosynthetic process' 'hypofunction of S-adenosylmethionine biosynthetic process' SubClassOf 'hypofunction of biosynthesis' 'hypofunction of S-adenosylmethionine biosynthetic process' SubClassOf 'PPARA (mol)' 'hypofunction of S-adenosylmethionine biosynthetic process' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004768 hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder] 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing glutathione level [mitochondrial disorder]' 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'hypofunction of S-adenosylmethionine biosynthetic process' 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'dysfunctioning of' some 'S-adenosylmethionine biosynthetic process' 'hypofunction of S-adenosylmethionine biosynthetic process [mitochondrial disorder]' SubClassOf 'hypofunction of transcription, DNA-templated' http://purl.obolibrary.org/obo/TXPO_0004769 decreasing glutathione level [mitochondrial disorder] 'decreasing glutathione level [mitochondrial disorder]' SubClassOf 'has result' some 'hypofunction of anti-oxidative stress[mitochondrial disorder]' 'decreasing glutathione level [mitochondrial disorder]' SubClassOf 'decreasing glutathione level' 'decreasing glutathione level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'decreasing glutathione level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'decreasing glutathione level [mitochondrial disorder]' SubClassOf 'has result' some 'glutathione depletion [Mitochondrial disorder]' 'decreasing glutathione level [mitochondrial disorder]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005127 http://purl.obolibrary.org/obo/TXPO_0004762 Increasing PVT1 level 'Increasing PVT1 level' SubClassOf 'increasing quantity' 'Increasing PVT1 level' SubClassOf 'has output' some 'PVT1' 'Increasing PVT1 level' SubClassOf 'has output' some ('PMAIP1 (mol)' and ('has quality' some 'inactive')) 'Increasing PVT1 level' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004763 Increasing PVT1 level [hepatocarcinogenesis] 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'Pvt1 (human) [hepatocarcinogenesis]' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing MIR150 level [hepatocarcinogenesis]' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'Increasing PVT1 level' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PMAIP1' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'PMAIP1 (predicted)(human) [hepatocarcinogenesis]' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'PMAIP1 (mol)' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'Increasing PVT1 level [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004764 Pvt1 (human) [hepatocarcinogenesis] 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'PVT1' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'caspase-3 activation' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'NLRP3 (canonical)[mitochondrial disorder]]' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Pvt1 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004765 Decreasing MIR150 level [hepatocarcinogenesis] 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'Decreasing miR-150 level' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing HILPDA level [hepatocarcinogenesis]' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'has input' some 'MIR150 (human) [hepatocarcinogenesis]' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PPARA (mol)' 'Decreasing MIR150 level [hepatocarcinogenesis]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004760 PTPRD gene promoter methylation 'PTPRD gene promoter methylation' SubClassOf 'DNA methylation' 'PTPRD gene promoter methylation' SubClassOf 'molecular activation' 'PTPRD gene promoter methylation' SubClassOf 'has output' some ('PKC' and ('has quality' some 'active')) http://purl.obolibrary.org/obo/TXPO_0004761 PTPRD gene promoter methylation [hepatocarcinogenesis] 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'PTPRD inactivation [hepatocarcinogenesis]' 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has output' some ('PKC' and ('has quality' some 'active')) 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'GSK3beta signal (primitive) [hepatocarcinogenesis]' 'PTPRD gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004715 Increasing PCNA level 'Increasing PCNA level' SubClassOf 'has output' some 'PCNA (mol)' 'Increasing PCNA level' SubClassOf 'increasing quantity' 'Increasing PCNA level' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004716 PCNA (mol) 'PCNA (mol)' SubClassOf 'molecule' 'PCNA (mol)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0004717 Increasing PCNA level [hepatocarcinogenesis] 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell division [hepatocarcinogenesis]' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PCNA (human) [hepatocarcinogenesis]' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'Increasing PCNA level' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'PCNA (human) [hepatocarcinogenesis]' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'PCNA (mol)' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing PCNA level [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004718 PCNA (human) [hepatocarcinogenesis] 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'PCNA (mol)' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'DNA damage [Mitochondrial disorder]' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'increasing production quantity of RNS' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'PCNA (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004711 PCK1 - inactive form (human) [Hepatocarcinogenesis] 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' SubClassOf 'PCK1 (human) [Hepatocarcinogenesis]' 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PCK1' 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004712 PCK1 activation 'PCK1 activation' SubClassOf 'has output' some ('PCK1 (mol)' and ('has quality' some 'active')) 'PCK1 activation' SubClassOf 'molecular activation' 'PCK1 activation' SubClassOf 'inactivation' 'PCK1 activation' SubClassOf 'has output' some ('PCK1 activation [mitochondrial disorder]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004713 PCK1 activation [mitochondrial disorder] 'PCK1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'malfunctioning of TCA cycle [Mitochondrial disorder]' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'has input' some 'PCK1 (predicted)(human) [mitochondrial damage]' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'PCK1 activation' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'has result' some 'negative regulation of gluconeogenesis [mitochondrial disorder]' 'PCK1 activation [mitochondrial disorder]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004714 negative regulation of gluconeogenesis [mitochondrial disorder] 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'negative regulation of gluconeogenesis' 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'Decreasing glucose level [mitochondrial disorder]' 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has result' some 'metabolic dysfunction of precursor metabolites and energy generation [mitochondrial disorder]' 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'has output' some ('Increasing PCNA level' and ('has quality' some 'inactive')) 'negative regulation of gluconeogenesis [mitochondrial disorder]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004710 PCK1 inactivation [hepatocarcinogenesis] 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'PCK1 inactivation' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'PCK1 - inactive form (human) [Hepatocarcinogenesis]' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'inactivation' 'PCK1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some ('PCK1 - inactive form (human) [Hepatocarcinogenesis]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004708 PANDA (human) [hepatocarcinogenesis] 'PANDA (human) [hepatocarcinogenesis]' SubClassOf 'PANDA' 'PANDA (human) [hepatocarcinogenesis]' SubClassOf 'has output' some ('PCK1 inactivation' and ('has quality' some 'inactive')) 'PANDA (human) [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004709 PCK1 inactivation 'PCK1 inactivation' SubClassOf 'has output' some ('NEAT1 (mol)' and ('has quality' some 'inactive')) 'PCK1 inactivation' SubClassOf 'inactivation' 'PCK1 inactivation' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004704 ORC1 - inactive form (human) [hepatocarcinogenesis] 'ORC1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'ORC1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'ORC1 (human) [hepatocarcinogenesis]' 'ORC1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'N-nitrosodiethylamine' 'ORC1 - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004705 PANDA 'PANDA' SubClassOf 'ncRNA gene of Homo sapiens' 'PANDA' SubClassOf 'N-hydroxy-2-acetamidofluorene' 'PANDA' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004706 Increasing PANDA level 'Increasing PANDA level' SubClassOf 'increasing quantity' 'Increasing PANDA level' SubClassOf 'has output' some 'PANDA' 'Increasing PANDA level' SubClassOf 'has output' some ('Increasing PANDA level [hepatocarcinogenesis]' and ('has quality' some 'inactive')) 'Increasing PANDA level' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004707 Increasing PANDA level [hepatocarcinogenesis] 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'Increasing PANDA level' 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing CXCL8 level' 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PANDA (human) [hepatocarcinogenesis]' 'Increasing PANDA level [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004700 UHRF1 production [hepatocarcinogenesis] 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'UHRF1 production' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'has output' some 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'Myc (mol)' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'family of' some 'Myc (mol)' 'UHRF1 production [hepatocarcinogenesis]' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0004701 ORC1 inactivation 'ORC1 inactivation' SubClassOf 'inactivation' 'ORC1 inactivation' SubClassOf 'has output' some ('ORC1 (mol)' and ('has quality' some 'inactive')) 'ORC1 inactivation' SubClassOf 'Myc (mol)' 'ORC1 inactivation' SubClassOf 'PPARGC1A (mol)' 'ORC1 inactivation' SubClassOf 'has role' some 'transcription regulator' http://purl.obolibrary.org/obo/TXPO_0004702 ORC1 (mol) 'ORC1 (mol)' SubClassOf 'molecule' 'ORC1 (mol)' SubClassOf 'MYC gene promoter demethylation' http://purl.obolibrary.org/obo/TXPO_0004703 ORC1 inactivation [hepatocarcinogenesis] 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'ORC1 inactivation' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Removing damaged DNA stress [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'ORC1 - inactive form (human) [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-hydroxy-2-acetamidofluorene [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'ORC1 (mol)' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Myc(mouse) [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CAR - activation state (mouse) [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has input' some 'Notch 3 (canonical) [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has input' some 'UHRF1 production [hepatocarcinogenesis]' 'ORC1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Notch 2 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004759 STAT3 activation [hepatocarcinogenesis] 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'STAT3 activation' 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'HCV infection [hepatocarcinogenesis]' 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'liver malfunction [hepatocarcinogenesis]' 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'STAT3 activation [hepatocarcinogenesis]' SubClassOf 'lipid storage in liver' http://purl.obolibrary.org/obo/TXPO_0004755 Increasing PROX1 level [hepatocarcinogenesis] 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'Increasing PROX1 level' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PROX1 (human)' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'PTPRD inactivation' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'PROX1 (mol)' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has input' some 'PROX1 (human)' 'Increasing PROX1 level [hepatocarcinogenesis]' SubClassOf 'has result' some 'STAT3 activation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004756 PROX1 (human) 'PROX1 (human)' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PROX1 (human)' SubClassOf 'PROX1 (mol)' 'PROX1 (human)' SubClassOf 'PIM3 (mol)' 'PROX1 (human)' SubClassOf 'has related human gene' some 'PIM3' http://purl.obolibrary.org/obo/TXPO_0004757 PTPRD inactivation 'PTPRD inactivation' SubClassOf 'inactivation' 'PTPRD inactivation' SubClassOf 'has output' some ('PTPRD (mol)' and ('has quality' some 'inactive')) 'PTPRD inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PTPRD inactivation' SubClassOf 'liver carcinogenesis dependent process' 'PTPRD inactivation' SubClassOf 'changing abnormal cellular structure' 'PTPRD inactivation' SubClassOf 'has result' some 'MST1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004758 PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis] 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'PTPRD (predicted)(human) [hepatocarcinogenesis]' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver malfunction' 'PTPRD - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004751 PMID:28584306 Increasing PROM1 level [hepatocarcinogenesis] 'Increasing PROM1 level [hepatocarcinogenesis]' SubClassOf 'has output' some 'PROM1 (human) [hepatocarcinogenesis]' 'Increasing PROM1 level [hepatocarcinogenesis]' SubClassOf 'Increasing PROM1 level' 'Increasing PROM1 level [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PROM1 level [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PROM1 level [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004752 PROM1 (human) [hepatocarcinogenesis] 'PROM1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PROM1 (human) [hepatocarcinogenesis]' SubClassOf 'PROM1 (mol)' 'PROM1 (human) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'PROM1 (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Increasing PROM1 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004753 Increasing PROX1 level 'Increasing PROX1 level' SubClassOf 'increasing quantity' 'Increasing PROX1 level' SubClassOf 'has output' some 'PROX1 (mol)' 'Increasing PROX1 level' SubClassOf 'has result' some 'Increasing IL-6 level [hepatocarcinogenesis]' 'Increasing PROX1 level' SubClassOf 'has pathway' some 'Increasing PROM1 level [hepatocarcinogenesis]' 'Increasing PROX1 level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PROX1 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PROX1 level' SubClassOf 'PROM1 (human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004754 PROX1 (mol) 'PROX1 (mol)' SubClassOf 'molecule' 'PROX1 (mol)' SubClassOf 'has output' some ('PIM3 (mol)' and ('has quality' some 'active')) 'PROX1 (mol)' SubClassOf 'molecular activation' http://purl.obolibrary.org/obo/TXPO_0004750 PROM1 (mol) 'PROM1 (mol)' SubClassOf 'molecule' 'PROM1 (mol)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005124 'PROM1 (mol)' SubClassOf 'has quality' some 'inactive' 'PROM1 (mol)' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004748 PROC gene promoter methylation [hepatocarcinogenesis] 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CCL4 [hepatocarcinogenesis]' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has input' some 'PROC (rat)＠肝発癌 [hepatocarcinogenesis]' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'PROC gene promoter methylation' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing PROC level' 'PROC gene promoter methylation [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004749 Increasing PROM1 level 'Increasing PROM1 level' SubClassOf 'increasing quantity' 'Increasing PROM1 level' SubClassOf 'has result' some 'connexin signaling (primitive)' 'Increasing PROM1 level' SubClassOf 'PROC gene promoter methylation' 'Increasing PROM1 level' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'Increasing PROM1 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Increasing PROM1 level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004745 Decreasing PROC level 'Decreasing PROC level' SubClassOf 'has input' some 'PROC (rat)＠肝発癌 [hepatocarcinogenesis]' 'Decreasing PROC level' SubClassOf 'has result' some 'negative regulation of EPCR signaling' 'Decreasing PROC level' SubClassOf 'has result' some 'negative regulation of APC signaling [hepatocarcinogenesis]' 'Decreasing PROC level' SubClassOf 'has output' some 'PROC (rat)＠肝発癌 [hepatocarcinogenesis]' 'Decreasing PROC level' SubClassOf 'has result' some 'Increasing ACSL4 level' http://purl.obolibrary.org/obo/TXPO_0004746 PROC (rat)＠肝発癌 [hepatocarcinogenesis] 'PROC (rat)＠肝発癌 [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'PROC (rat)＠肝発癌 [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004747 PROC gene promoter methylation 'PROC gene promoter methylation' SubClassOf 'DNA methylation' 'PROC gene promoter methylation' SubClassOf 'inactivation' 'PROC gene promoter methylation' SubClassOf 'has output' some ('PROC gene promoter methylation [hepatocarcinogenesis]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004740 Hypofunction of PPARGC1A gene expression 'Hypofunction of PPARGC1A gene expression' SubClassOf 'hypofunction of transcription, DNA-templated' 'Hypofunction of PPARGC1A gene expression' SubClassOf 'molecular activation' 'Hypofunction of PPARGC1A gene expression' SubClassOf 'has output' some ('PCK1 (mol)' and ('has quality' some 'active')) http://purl.obolibrary.org/obo/TXPO_0004741 PPARGC1A (canonical) [mitochondrial disorder] 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'PPARGC1A (mol)' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'Hypofunction of PPARGC1A gene expression' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'malfunctioning of TCA cycle [Mitochondrial disorder]' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'has input' some 'PCK1 (predicted)(human) [mitochondrial damage]' 'PPARGC1A (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'PPARA - activation state (mouse) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004742 PPARA - activation state (mouse) [hepatocarcinogenesis] 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'active' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'PPARA(mouse) [hepatocarcinogenesis]' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'negative regulation of gluconeogenesis' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'has result' some 'metabolic dysfunction of precursor metabolites and energy generation [mitochondrial disorder]' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PPARA - activation state (mouse) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increase in mitochondrial calcium level' http://purl.obolibrary.org/obo/TXPO_0004743 Decreasing PROC level 'Decreasing PROC level' SubClassOf 'decreasing quantity' 'Decreasing PROC level' SubClassOf 'has input' some 'PROC (mol)' 'Decreasing PROC level' SubClassOf 'increasing quantity' 'Decreasing PROC level' SubClassOf 'has output' some 'PROC (mol)' http://purl.obolibrary.org/obo/TXPO_0004737 Negative regulation of caspase-3 activation [hepatocarcinogenesis] 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of apoptotic process [hepatocarcinogenesis]' 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'negative regulation of caspase-3 activation' 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'caspase-3 activation' 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'has output' some ('NEAT1 (mol)' and ('has quality' some 'inactive')) 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' SubClassOf 'inactivation' http://purl.obolibrary.org/obo/TXPO_0004738 Increasing PPARA level 'Increasing PPARA level' SubClassOf 'increasing quantity' 'Increasing PPARA level' SubClassOf 'has output' some 'PPARA (mol)' 'Increasing PPARA level' SubClassOf 'Negative regulation of caspase-3 activation [hepatocarcinogenesis]' 'Increasing PPARA level' SubClassOf 'has output' some 'PPARA(canonical) [hepatocarcinogenesis]' 'Increasing PPARA level' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'Increasing PPARA level' SubClassOf 'liver carcinogenesis dependent process' 'Increasing PPARA level' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004739 PPARA(canonical) [hepatocarcinogenesis] 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf 'PPARA (mol)' 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PCK1' 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PPARA(canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005122 http://purl.obolibrary.org/obo/TXPO_0004733 PKC activation 'PKC activation' SubClassOf 'has output' some ('PKC' and ('has quality' some 'active')) 'PKC activation' SubClassOf 'molecular activation' 'PKC activation' SubClassOf 'ncRNA gene of Homo sapiens' http://purl.obolibrary.org/obo/TXPO_0004734 PKC activation [mitochondrial disorder] 'PKC activation [mitochondrial disorder]' SubClassOf 'has result' some 'negative regulation of AKT signaling [mitochondrial disorder]' 'PKC activation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PKC activation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'PKC activation [mitochondrial disorder]' SubClassOf 'PKC activation' 'PKC activation [mitochondrial disorder]' SubClassOf 'has output' some ('PKC' and ('has quality' some 'active')) 'PKC activation [mitochondrial disorder]' SubClassOf 'increasing quantity' 'PKC activation [mitochondrial disorder]' SubClassOf 'has output' some 'PKC activation' http://purl.obolibrary.org/obo/TXPO_0004735 PMAIP1 inactivation 'PMAIP1 inactivation' SubClassOf 'inactivation' 'PMAIP1 inactivation' SubClassOf 'has output' some ('PMAIP1 (mol)' and ('has quality' some 'inactive')) 'PMAIP1 inactivation' SubClassOf 'liver carcinogenesis dependent process' 'PMAIP1 inactivation' SubClassOf 'has output' some 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'PMAIP1 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PMAIP1 inactivation' SubClassOf 'PKC activation [mitochondrial disorder]' 'PMAIP1 inactivation' SubClassOf 'has result' some 'CXCR3(canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004736 PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis] 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'PMAIP1 (predicted)(human) [hepatocarcinogenesis]' 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PMAIP1' 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'PMAIP1 (mol)' 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PMAIP1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'PKC activation' http://purl.obolibrary.org/obo/TXPO_0004730 liver malfunction [hepatocarcinogenesis] 'liver malfunction [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'liver malfunction [hepatocarcinogenesis]' SubClassOf 'liver malfunction' 'liver malfunction [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'liver malfunction [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'liver malfunction [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004731 lipid storage in liver [hepatocarcinogenesis] 'lipid storage in liver [hepatocarcinogenesis]' SubClassOf 'lipid storage in liver' 'lipid storage in liver [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'lipid storage in liver [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing CXCL8 level' 'lipid storage in liver [hepatocarcinogenesis]' SubClassOf 'changing abnormal cellular structure [hepatocarcinogenesis]' 'lipid storage in liver [hepatocarcinogenesis]' SubClassOf 'has output' some 'neovascularization [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004732 neovascularization [hepatocarcinogenesis] 'neovascularization [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'neovascularization [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'neovascularization [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'neovascularization [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'neovascularization [hepatocarcinogenesis]' SubClassOf 'biological structure formation' 'neovascularization [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'neovascularization [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005121 'neovascularization [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004726 PIM3 activation 'PIM3 activation' SubClassOf 'molecular activation' 'PIM3 activation' SubClassOf 'has output' some ('PIM3 (mol)' and ('has quality' some 'active')) 'PIM3 activation' SubClassOf 'PPARGC1A (mol)' 'PIM3 activation' SubClassOf 'Notch 2 (mol)' http://purl.obolibrary.org/obo/TXPO_0004727 PIM3 activation [hepatocarcinogenesis] 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'liver malfunction [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'PIM3 activation' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has input' some 'PIM3 (human) [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'changing abnormal cellular structure [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'lipid storage in liver [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'positive regulation of cell cycle [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'has result' some 'neovascularization [hepatocarcinogenesis]' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'PIM3 activation [hepatocarcinogenesis]' SubClassOf 'Notch 3 (mol)' http://purl.obolibrary.org/obo/TXPO_0004728 PIM3 (human) [hepatocarcinogenesis] 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'PIM3 (mol)' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PIM3' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'JUN(mouse) [hepatocarcinogenesis]' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CDK2 level [hepatocarcinogenesis]' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'PIM3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'ACSL4 (mol)' http://purl.obolibrary.org/obo/TXPO_0004729 changing abnormal cellular structure [hepatocarcinogenesis] 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'changing abnormal cellular structure' 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'has result' some 'nodule formation [hepatocarcinogenesis]' 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'inactivation' 'changing abnormal cellular structure [hepatocarcinogenesis]' SubClassOf 'has output' some ('liver malfunction [hepatocarcinogenesis]' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004722 PHB - inactive form (human) [hepatocarcinogenesis] 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'PHB (human) [hepatocarcinogenesis]' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'hypofunction of anti-oxidative stress[mitochondrial disorder]' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'FZD7 (mol)' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PHB - inactive form (human) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0004723 PI3K signal transduction pathway 'PI3K signal transduction pathway' SubClassOf 'signaling pathway' 'PI3K signal transduction pathway' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PI3K signal transduction pathway' SubClassOf 'dysfunctioning of' some 'lipid biosynthetic process' 'PI3K signal transduction pathway' SubClassOf 'mitochondrial disorder dependent process' 'PI3K signal transduction pathway' SubClassOf 'hypofunction of lipid biosynthesis' http://purl.obolibrary.org/obo/TXPO_0004724 PI3K signaling (primitive) 'PI3K signaling (primitive)' SubClassOf 'has pathway' some 'PI3K signal transduction pathway' 'PI3K signaling (primitive)' SubClassOf 'has pathway' some 'Notch signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004725 PI3K signaling (primitive) [hepatocarcinogenesis] 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'PI3K signaling (primitive)' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'PI3K signal transduction pathway' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'has result' some 'AKT signaling (primitive) [hepatocarcinogenesis]' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'Notch 1 (mol)' 'PI3K signaling (primitive) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004720 PHB (mol) 'PHB (mol)' SubClassOf 'molecule' 'PHB (mol)' SubClassOf 'has result' some 'PI3K signal transduction pathway' 'PHB (mol)' SubClassOf 'has result' some 'PHB - inactive form (human) [hepatocarcinogenesis]' 'PHB (mol)' SubClassOf 'mitochondrial disorder dependent process' 'PHB (mol)' SubClassOf 'has result' some 'hypofunction of mitochondrial fatty acid beta-oxidation [Mitochondrial disorder]' 'PHB (mol)' SubClassOf 'PHB inactivation' 'PHB (mol)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'PHB (mol)' SubClassOf 'has output' some 'PHB inactivation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004721 PHB inactivation [hepatocarcinogenesis] 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'PHB - inactive form (human) [hepatocarcinogenesis]' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'NfkB signaling (primitive) [hepatocarcinogenesis]' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'JNK signaling (primitive) [hepatocarcinogenesis]' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'PHB inactivation' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'PHB inactivation [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005120 'PHB inactivation [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004719 PHB inactivation 'PHB inactivation' SubClassOf 'has output' some ('PHB (mol)' and ('has quality' some 'inactive')) 'PHB inactivation' SubClassOf 'has output' some ('NRF2 (mol)' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004898 Increasing ketone body level [mitochondrial disorder] 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'has result' some 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'Increasing ketone body level' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'has output' some 'ketone body' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'cell proliferation' 'Increasing ketone body level [mitochondrial disorder]' SubClassOf 'has output' some (('cell' and ('has quality' some 'neoplastic (quality)')) and ('has quality' some 'increased number (quality)')) http://purl.obolibrary.org/obo/TXPO_0004899 induction of genomic instability 'induction of genomic instability' SubClassOf 'changing state' 'induction of genomic instability' SubClassOf 'has output' some (('cell' and ('has quality' some 'neoplastic (quality)')) and ('has quality' some 'increased number (quality)')) 'induction of genomic instability' SubClassOf 'Increasing ketone body level [mitochondrial disorder]' 'induction of genomic instability' SubClassOf 'has result' some 'Decreasing GPHN level' 'induction of genomic instability' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'induction of genomic instability' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004894 hyperfunction of gluconeogenesis 'hyperfunction of gluconeogenesis' SubClassOf 'hyperfunction of biosynthesis' 'hyperfunction of gluconeogenesis' SubClassOf 'hyperfunction of' some 'gluconeogenesis' 'hyperfunction of gluconeogenesis' SubClassOf 'KRAS (mol)' http://purl.obolibrary.org/obo/TXPO_0004895 decreasing glutathione level 'decreasing glutathione level' SubClassOf 'decreasing quantity' 'decreasing glutathione level' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'decreasing glutathione level' SubClassOf 'KRAS (mol)' http://purl.obolibrary.org/obo/TXPO_0004896 Negative regulation of glutathione transport 'Negative regulation of glutathione transport' SubClassOf 'negative regulation of transport' 'Negative regulation of glutathione transport' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'Negative regulation of glutathione transport' SubClassOf 'NRAS (mol)' http://purl.obolibrary.org/obo/TXPO_0004897 Increasing ketone body level 'Increasing ketone body level' SubClassOf 'increasing quantity' 'Increasing ketone body level' SubClassOf 'positive regulation of cell division' http://purl.obolibrary.org/obo/TXPO_0004890 increasing glucose level 'increasing glucose level' SubClassOf 'increasing quantity' 'increasing glucose level' SubClassOf 'mutation' http://purl.obolibrary.org/obo/TXPO_0004891 increasing glucose level [mitochondrial disorder] 'increasing glucose level [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'increasing glucose level' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing mitochondrial membrane potential [Mitochondrial disorder]' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'increasing glucose level [mitochondrial disorder]' SubClassOf '7,12-dimethyltetraphene' 'increasing glucose level [mitochondrial disorder]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004892 decreasing glucose level 'decreasing glucose level' SubClassOf 'decreasing quantity' 'decreasing glucose level' SubClassOf '4-(phenylazo)aniline' 'decreasing glucose level' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0004893 Decreasing glucose level [mitochondrial disorder] 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'decreasing glucose level' 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'Decreasing glucose level [mitochondrial disorder]' SubClassOf 'HRAS (mol)' http://purl.obolibrary.org/obo/TXPO_0002228 PLA2G2E (human)positively regulator of immune response[Phospholipidosis] 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'has role' some 'phospholipase' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'relateds assay' some 'in vitro assay' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'family of' some 'PLA2 (mol)' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'PLA2G2E (mol)' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'has role' some 'positive regulator of immune response' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'phospholipidosis dependent molecule (human in vitro)' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'toxicological imbalance' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'small (functioning performance value)')))) 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'has part' some 'balance state' 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'small (functioning performance value)')))) http://purl.obolibrary.org/obo/TXPO_0004887 Increasing glucagon level 'Increasing glucagon level' SubClassOf 'increasing quantity' 'Increasing glucagon level' SubClassOf 'MIR150' 'Increasing glucagon level' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004888 Increasing glucagon level [mitochondrial disorder] 'Increasing glucagon level [mitochondrial disorder]' SubClassOf 'Increasing glucagon level' 'Increasing glucagon level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing glucagon level [mitochondrial disorder]' SubClassOf 'has result' some 'hyperfunction of CYP2E1 gene expression [mitochondrial disorder]' 'Increasing glucagon level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing glucagon level [mitochondrial disorder]' SubClassOf 'changing shape' http://purl.obolibrary.org/obo/TXPO_0004889 glucose homeostasis imbalance [mitochondrial disorder] 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'glucose homeostasis imbalance' 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'has result' some 'Malfunctioning of insulin signaling [mitochondrial disorder]' 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'glucose homeostasis imbalance [mitochondrial disorder]' SubClassOf 'p53 (mol)' http://purl.obolibrary.org/obo/TXPO_0004883 cardiolipin peroxidation 'cardiolipin peroxidation' SubClassOf 'has input' some 'cardiolipin' 'cardiolipin peroxidation' SubClassOf 'phospholipid peroxidation' 'cardiolipin peroxidation' SubClassOf 'liver carcinogenesis dependent process' 'cardiolipin peroxidation' SubClassOf 'HHIP (human) [hepatocarcinogenesis]' 'cardiolipin peroxidation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'cardiolipin peroxidation' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004884 phospholipid peroxidation 'phospholipid peroxidation' SubClassOf 'lipoperoxidation' 'phospholipid peroxidation' SubClassOf 'NDUFS2 - inactive form (human)[mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004885 Chlorendic Acid 'Chlorendic Acid' SubClassOf 'organic molecular entity' 'Chlorendic Acid' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'Chlorendic Acid' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005119 http://purl.obolibrary.org/obo/TXPO_0004886 Chlorendic Acid [hepatocarcinogenesis] 'Chlorendic Acid [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'Chlorendic Acid [hepatocarcinogenesis]' SubClassOf 'Chlorendic Acid' 'Chlorendic Acid [hepatocarcinogenesis]' SubClassOf 'decreasing quantity' 'Chlorendic Acid [hepatocarcinogenesis]' SubClassOf 'has input' some 'MIR150' http://purl.obolibrary.org/obo/TXPO_0004880 autophagy [mitochondrial disorder] 'autophagy [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'autophagy [mitochondrial disorder]' SubClassOf 'autophagy' 'autophagy [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'autophagy [mitochondrial disorder]' SubClassOf 'keeping position' http://purl.obolibrary.org/obo/TXPO_0004881 autophagy [hepatocarcinogenesis] 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'autophagy' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has participant' some 'BECN1 (human) [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has participant' some 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'cardiolipin peroxidation' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing DNMT1 level [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'BECN1 (human) [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has participant' some 'SCAPER (predicted)(human) [hepatocarcinogenesis]' 'autophagy [hepatocarcinogenesis]' SubClassOf 'has result' some 'IP-10 signaling (primitive)' 'autophagy [hepatocarcinogenesis]' SubClassOf 'autophagy [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0004882 BECN1 (human) [hepatocarcinogenesis] 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'BECN1 (mol)' 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'BECN1 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004836 negative regulation of caspase-3 activation 'negative regulation of caspase-3 activation' SubClassOf 'negative regulation of activation' 'negative regulation of caspase-3 activation' SubClassOf 'negatively regulates' some 'caspase-3 activation' 'negative regulation of caspase-3 activation' SubClassOf 'MTOR (mol)' 'negative regulation of caspase-3 activation' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004837 negative regulation of activation 'negative regulation of activation' SubClassOf 'negative regulation process' 'negative regulation of activation' SubClassOf 'negatively regulates' some 'activating' 'negative regulation of activation' SubClassOf 'has participant' some 'CDH1 (canonical) [hepatocarcinogenesis]' 'negative regulation of activation' SubClassOf 'has result' some 'Decreasing GPHN level' 'negative regulation of activation' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of activation' SubClassOf 'response to hypoxia' 'negative regulation of activation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of activation' SubClassOf 'has result' some 'mitochondria morphology change' 'negative regulation of activation' SubClassOf 'has result' some 'HNF4A - inactive form (canonical) [hepatocarcinogenesis]' 'negative regulation of activation' SubClassOf 'has result' some 'IL-6(human)[hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004838 cytoplasmic sequestering of cyclin A 'cytoplasmic sequestering of cyclin A' SubClassOf 'keeping position' 'cytoplasmic sequestering of cyclin A' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004839 cytoplasmic sequestering of cyclin A [hepatocarcinogenesis] 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has result' some 'Cell Transformation, Neoplastic [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has result' some 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has result' some 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'cytoplasmic sequestering of cyclin A' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has result' some 'induction of genomic instability [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has participant' some 'SCAPER (predicted)(human) [hepatocarcinogenesis]' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'cytoplasmic sequestering of cyclin A' 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004832 beta-catenin signal transduction pathway 'beta-catenin signal transduction pathway' SubClassOf 'signaling pathway' 'beta-catenin signal transduction pathway' SubClassOf 'signaling [biological] (primitive)' 'beta-catenin signal transduction pathway' SubClassOf 'has pathway' some 'tumor necrosis factor-mediated signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004833 beta-catenin signal (primitive) 'beta-catenin signal (primitive)' SubClassOf 'has pathway' some 'beta-catenin signal transduction pathway' 'beta-catenin signal (primitive)' SubClassOf 'signaling [biological] (primitive)' 'beta-catenin signal (primitive)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'beta-catenin signal (primitive)' SubClassOf 'has participant' some 'TNFΑ (canonical)[mitochondrial disorder]' 'beta-catenin signal (primitive)' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'beta-catenin signal (primitive)' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'beta-catenin signal (primitive)' SubClassOf 'beta-catenin signal transduction pathway' 'beta-catenin signal (primitive)' SubClassOf 'has pathway' some 'tumor necrosis factor-mediated signaling pathway' 'beta-catenin signal (primitive)' SubClassOf 'mitochondrial disorder dependent process' 'beta-catenin signal (primitive)' SubClassOf 'has result' some 'Increasing ACSL1 level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004834 CDH1 - inactive form (canonical) [hepatocarcinogenesis] 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'CDH1 (canonical) [hepatocarcinogenesis]' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Ctnnb1 (canonical) [hepatocarcinogenesis]' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'tumor necrosis factor-mediated signaling pathway' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CDH1 - inactive form (canonical) [hepatocarcinogenesis]' SubClassOf 'beta-catenin signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004835 Ctnnb1 (canonical) [hepatocarcinogenesis] 'Ctnnb1 (canonical) [hepatocarcinogenesis]' SubClassOf 'Ctnnb1 (mol)' 'Ctnnb1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'Ctnnb1 (canonical) [hepatocarcinogenesis]' SubClassOf 'TNF-a (mol)' 'Ctnnb1 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004830 YAP signaling (primitive) 'YAP signaling (primitive)' SubClassOf 'has participant' some 'YAP1 (mol)' 'YAP signaling (primitive)' SubClassOf 'has pathway' some 'YAP signal transduction pathway' 'YAP signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'YAP signaling (primitive)' SubClassOf 'cytolysis' 'YAP signaling (primitive)' SubClassOf 'mitochondrial disorder dependent process' 'YAP signaling (primitive)' SubClassOf 'has result' some 'necrosis [mitochondrial disorder]' 'YAP signaling (primitive)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'YAP signaling (primitive)' SubClassOf 'has result' some 'apoptotic process [Mitochondrial disorder]' 'YAP signaling (primitive)' SubClassOf 'occurs in' some 'cell' http://purl.obolibrary.org/obo/TXPO_0004831 YAP1 (canonical) [hepatocarcinogenesis] 'YAP1 (canonical) [hepatocarcinogenesis]' SubClassOf 'YAP1 (mol)' 'YAP1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'YAP1 (canonical) [hepatocarcinogenesis]' SubClassOf 'TLR4 (mol)' 'YAP1 (canonical) [hepatocarcinogenesis]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0004829 YAP signal transduction pathway 'YAP signal transduction pathway' SubClassOf 'signaling pathway' 'YAP signal transduction pathway' SubClassOf 'has pathway' some 'TLR4 signaling pathway' 'YAP signal transduction pathway' SubClassOf 'TLR signaling (primitive)' 'YAP signal transduction pathway' SubClassOf 'has agent' some 'TLR4 (mol)' http://purl.obolibrary.org/obo/TXPO_0004825 FZD5 (canonical) [hepatocarcinogenesis] 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD5 (mol)' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'pentadecafluorooctanoic acid' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'FZD1 (canonical) [hepatocarcinogenesis]' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD2 (canonical) [hepatocarcinogenesis]' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'FZD6 (canonical) [hepatocarcinogenesis]' 'FZD5 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004826 FZD6 (canonical) [hepatocarcinogenesis] 'FZD6 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD6 (mol)' 'FZD6 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD6 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'FZD6 (canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005135 http://purl.obolibrary.org/obo/TXPO_0004827 FZD7 (canonical) [hepatocarcinogenesis] 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD7 (mol)' 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'family of' some 'TGF-beta family' 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'TGFbeta1 (mol)' 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'FZD7 (canonical) [hepatocarcinogenesis]' SubClassOf 'TGF-beta1' http://purl.obolibrary.org/obo/TXPO_0004828 FZD9 (canonical) [hepatocarcinogenesis] 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD9 (mol)' 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'COX-2 (canonical) [hepatocarcinogenesis]' 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FZD9 (canonical) [hepatocarcinogenesis]' SubClassOf 'CYP2A13 (mol)' http://purl.obolibrary.org/obo/TXPO_0004821 WNT signal transduction pathway 'WNT signal transduction pathway' SubClassOf 'signaling pathway' 'WNT signal transduction pathway' SubClassOf 'has participant' some 'WNT signaling (primitive)' 'WNT signal transduction pathway' SubClassOf 'VEGF (canonical) [hepatocarcinogenesis]' 'WNT signal transduction pathway' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'WNT signal transduction pathway' SubClassOf 'mitochondrial disorder dependent process' 'WNT signal transduction pathway' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004822 WNT signaling (primitive) 'WNT signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'WNT signaling (primitive)' SubClassOf 'has participant' some 'Wnt' 'WNT signaling (primitive)' SubClassOf 'has pathway' some 'WNT signal transduction pathway' 'WNT signaling (primitive)' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'WNT signaling (primitive)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005134 http://purl.obolibrary.org/obo/TXPO_0004823 FZD1 (canonical) [hepatocarcinogenesis] 'FZD1 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD1 (mol)' 'FZD1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD1 (canonical) [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004824 FZD2 (canonical) [hepatocarcinogenesis] 'FZD2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'FZD2 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD2 (mol)' 'FZD2 (canonical) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'FZD2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'FZD1 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004820 VEGF (canonical) [hepatocarcinogenesis] 'VEGF (canonical) [hepatocarcinogenesis]' SubClassOf 'has role' some 'growth factor role' 'VEGF (canonical) [hepatocarcinogenesis]' SubClassOf 'VEGF (mol)' 'VEGF (canonical) [hepatocarcinogenesis]' SubClassOf 'has role' some 'ligand' 'VEGF (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'VEGF (canonical) [hepatocarcinogenesis]' SubClassOf 'hypofunction of transcription, DNA-templated' http://purl.obolibrary.org/obo/TXPO_0004818 UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis] 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'UHRF1' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'hepatic fibrosis' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'occurs in' some 'liver' 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004819 Increasing VEGF level 'Increasing VEGF level' SubClassOf 'has output' some 'AGGF1 (mol)' 'Increasing VEGF level' SubClassOf 'increasing quantity' 'Increasing VEGF level' SubClassOf 'organic molecular entity' http://purl.obolibrary.org/obo/TXPO_0004814 DNMT1 (human) [hepatocarcinogenesis] 'DNMT1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'DNMT1 (human) [hepatocarcinogenesis]' SubClassOf 'DNMT1 (mol)' 'DNMT1 (human) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'DNMT1 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'USP7 (human) [hepatocarcinogenesis]' 'DNMT1 (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'trimeric UHRF1 repression complex' http://purl.obolibrary.org/obo/TXPO_0004815 USP7 (human) [hepatocarcinogenesis] 'USP7 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'USP7 (human) [hepatocarcinogenesis]' SubClassOf 'USP7 (mol)' 'USP7 (human) [hepatocarcinogenesis]' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0004816 UHRF1 inactivation 'UHRF1 inactivation' SubClassOf 'has output' some ('UHRF1 (mol)' and ('has quality' some 'inactive')) 'UHRF1 inactivation' SubClassOf 'inactivation' 'UHRF1 inactivation' SubClassOf 'has result' some 'Increasing PPARA level [hepatocarcinogenesis]' 'UHRF1 inactivation' SubClassOf 'has result' some 'ACSL4 (mol)' 'UHRF1 inactivation' SubClassOf 'has pathway' some 'trimeric UHRF1 repression complex' 'UHRF1 inactivation' SubClassOf 'has participant' some 'UHRF1 inactivation [hepatocarcinogenesis]' 'UHRF1 inactivation' SubClassOf 'has result' some 'ACSL1 (mol)' 'UHRF1 inactivation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'UHRF1 inactivation' SubClassOf 'liver carcinogenesis dependent process' 'UHRF1 inactivation' SubClassOf 'DNMT1 (human) [hepatocarcinogenesis]' 'UHRF1 inactivation' SubClassOf 'has result' some 'Increasing ACSL4 level' 'UHRF1 inactivation' SubClassOf 'has result' some 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004817 UHRF1 inactivation [hepatocarcinogenesis] 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'has output' some 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'UHRF1 inactivation' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'epithelial to mesenchymal transition [hepatocarcinogenesis]' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'has result' some 'Increasing CXCR4 level [hepatocarcinogenesis]' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'USP7 (human) [hepatocarcinogenesis]' 'UHRF1 inactivation [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004810 EPB41L3 (rat) [hepatocarcinogenesis] 'EPB41L3 (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'EPB41L3 (rat) [hepatocarcinogenesis]' SubClassOf 'EPB41L3 (mol)' 'EPB41L3 (rat) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' 'EPB41L3 (rat) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004811 negative regulation of actin cytoskeleton organization [hepatocarcinogenesis] 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'negative regulation of actin cytoskeleton organization' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'actin cytoskeleton organization and biogenesis' 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004812 TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells. Negative regulation of adherens junction assembly [hepatocarcinogenesis] 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'negative regulation of adherens junction assembly' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'has result' some 'Tumor cell proliferation [Hepatocarcinogenesis]' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'has result' some 'metastasis [hepatocarcinogenesis]' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'liver carcinogenesis dependent process' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'has result' some 'tumor cell invasion [hepatocarcinogenesis]' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005132 http://purl.obolibrary.org/obo/TXPO_0004813 trimeric UHRF1 repression complex 'trimeric UHRF1 repression complex' SubClassOf 'has role' some 'transcription regulator' 'trimeric UHRF1 repression complex' SubClassOf 'molecular complex' 'trimeric UHRF1 repression complex' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004807 negative regulation of TSLC signaling 'negative regulation of TSLC signaling' SubClassOf 'negatively regulates' some 'TSLC signal transduction pathway' 'negative regulation of TSLC signaling' SubClassOf 'negative regulation of signaling' 'negative regulation of TSLC signaling' SubClassOf 'negatively regulates' some 'TSLC signaling (primitive)' 'negative regulation of TSLC signaling' SubClassOf 'signaling [biological] (primitive)' 'negative regulation of TSLC signaling' SubClassOf 'has pathway' some 'TSLC signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004808 negative regulation of TSLC signaling [hepatocarcinogenesis] 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'CADM1 (rat) [hepatocarcinogenesis]' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'negative regulation of actin cytoskeleton organization [hepatocarcinogenesis]' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'negative regulation of TSLC signaling' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'TSLC signal transduction pathway' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'EPB41L3 (rat) [hepatocarcinogenesis]' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'TSLC signaling (primitive)' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has result' some 'TSLC1 and DAL‐1 are components of the TSLC cascade, which participates in organizing the actin cytoskeleton and constructing stable cell‐to‐cell adhesion. It is thought that disturbances in the cell adhesion system are critical factors in the growth, invasion and metastasis of cancer cells.' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has participant' some 'N-nitrosodiethylamine [hepatocarcinogenesis]' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'has role' some 'positive regulator of tumorigenesis role' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'negative regulation of TSLC signaling [hepatocarcinogenesis]' SubClassOf 'STAT3 (mol)' http://purl.obolibrary.org/obo/TXPO_0004809 CADM1 (rat) [hepatocarcinogenesis] 'CADM1 (rat) [hepatocarcinogenesis]' SubClassOf 'CADM1 (mol)' 'CADM1 (rat) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (rat)' 'CADM1 (rat) [hepatocarcinogenesis]' SubClassOf 'Increasing ketone body level' 'CADM1 (rat) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CADM1 (rat) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0004803 TNF signaling [mitochondrial disorder] 'TNF signaling [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has result' some 'Iron accumulation [mitochondrial disorder]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has pathway' some 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'has output' some 'response to hypoxia [hepatocarcinogenesis]' 'TNF signaling [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004804 response to hypoxia [hepatocarcinogenesis] 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'response to hypoxia' 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'has participant' some 'HIF1A(canonical) [hepatocarcinogenesis]' 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' 'response to hypoxia [hepatocarcinogenesis]' SubClassOf 'SPTLC3 (mol)' http://purl.obolibrary.org/obo/TXPO_0004806 TSLC signaling (primitive) 'TSLC signaling (primitive)' SubClassOf 'has pathway' some 'TSLC signal transduction pathway' 'TSLC signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'TSLC signaling (primitive)' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004800 TLR4 (canonical) [mitochondrial disorder] 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'TLR4 (mol)' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'has output' some 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'TLR4 signaling (primitive)' 'TLR4 (canonical) [mitochondrial disorder]' SubClassOf 'has agent' some 'Hippo signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004801 tumor necrosis factor-mediated signaling pathway [mitochondrial disorder] 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' SubClassOf 'tumor necrosis factor-mediated signaling pathway' 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005131 'tumor necrosis factor-mediated signaling pathway [mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0004802 TNF signaling (primitive) 'TNF signaling (primitive)' SubClassOf 'signaling [biological] (primitive)' 'TNF signaling (primitive)' SubClassOf 'has pathway' some 'tumor necrosis factor-mediated signaling pathway' 'TNF signaling (primitive)' SubClassOf 'increasing quantity' 'TNF signaling (primitive)' SubClassOf 'has output' some 'SPTLC3 (mol)' http://purl.obolibrary.org/obo/TXPO_0004876 alcohol [hepatocarcinogenesis] 'alcohol [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'alcohol [hepatocarcinogenesis]' SubClassOf 'alcohol' 'alcohol [hepatocarcinogenesis]' SubClassOf 'Src (mol)' http://purl.obolibrary.org/obo/TXPO_0004877 NLRP3 (canonical)[mitochondrial disorder]] 'NLRP3 (canonical)[mitochondrial disorder]]' SubClassOf 'NLRP3 (mol)' 'NLRP3 (canonical)[mitochondrial disorder]]' SubClassOf 'lipidosis dependent molecule (canonical)' 'NLRP3 (canonical)[mitochondrial disorder]]' SubClassOf 'negatively regulates' some 'caspase-3 activation' 'NLRP3 (canonical)[mitochondrial disorder]]' SubClassOf 'hypofunction of oxysterol biosynthesis' http://purl.obolibrary.org/obo/TXPO_0004878 hypofunction of oxysterol biosynthesis 'hypofunction of oxysterol biosynthesis' SubClassOf 'has result' some 'decreasing cholesterol concentration in blood' 'hypofunction of oxysterol biosynthesis' SubClassOf 'dysfunctioning of' some 'cholesterol biosynthetic process' 'hypofunction of oxysterol biosynthesis' SubClassOf 'hypofunction of lipid biosynthesis' 'hypofunction of oxysterol biosynthesis' SubClassOf 'negative regulation process' 'hypofunction of oxysterol biosynthesis' SubClassOf 'negatively regulates' some 'activating' http://purl.obolibrary.org/obo/TXPO_0004879 hypofunction of oxysterol biosynthesis [mitochondrial disorder] 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'hypofunction of oxysterol biosynthesis' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'family of' some 'caspase (family)' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'caspase-3' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'has related human gene' some 'CASP3' 'hypofunction of oxysterol biosynthesis [mitochondrial disorder]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004872 positive regulation of arachidonic acid metabolic process 'positive regulation of arachidonic acid metabolic process' SubClassOf 'positive regulation process' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'positively regulates' some 'arachidonic acid metabolism' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'release of inflammatory DAMPs' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'has quality' some 'inactive' 'positive regulation of arachidonic acid metabolic process' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004873 Decreasing arachidonic acid level 'Decreasing arachidonic acid level' SubClassOf 'has input' some 'arachidonic acid' 'Decreasing arachidonic acid level' SubClassOf 'decreasing quantity' 'Decreasing arachidonic acid level' SubClassOf 'PPARGC1A (mol)' 'Decreasing arachidonic acid level' SubClassOf 'Ctnnb1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004874 aristolochic acid [hepatocarcinogenesis] 'aristolochic acid [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'aristolochic acid [hepatocarcinogenesis]' SubClassOf 'aristolochic acid' 'aristolochic acid [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'aristolochic acid [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'aristolochic acid [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/GO_0031532 'aristolochic acid [hepatocarcinogenesis]' SubClassOf 'has result' some 'APC signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004875 alcohol intake [hepatocarcinogenesis] 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has result' some 'proto-oncogene mutation [hepatocarcinogenesis]' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has input' some 'alcohol [hepatocarcinogenesis]' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has result' some 'Hedgehog signaling [hepatocarcinogenesis]' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has result' some 'hepatic cirrhosis [hepatocarcinogenesis]' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'alcohol intake' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Src (mol)' 'alcohol intake [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'TSLC signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0004870 Cyp1A1 (canonical) [hepatocarcinogenesis] 'Cyp1A1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'Cyp1A1 (canonical) [hepatocarcinogenesis]' SubClassOf 'Cyp1A1 (mol)' 'Cyp1A1 (canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP1A1' 'Cyp1A1 (canonical) [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004871 tumor cell survial [hepatocarcinogenesis] 'tumor cell survial [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'tumor cell survial [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'tumor cell survial [hepatocarcinogenesis]' SubClassOf 'tumor cell survial' 'tumor cell survial [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'Cyp1A1 (canonical) [hepatocarcinogenesis]' 'tumor cell survial [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004869 CYP3A7 (canonical) [hepatocarcinogenesis] 'CYP3A7 (canonical) [hepatocarcinogenesis]' SubClassOf 'CYP3A7 (mol)' 'CYP3A7 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CYP3A7 (canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP3A7' 'CYP3A7 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'CYP3A7 (canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005137 http://purl.obolibrary.org/obo/TXPO_0004865 CYP2A13 (canonical) [hepatocarcinogenesis] 'CYP2A13 (canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP2A13' 'CYP2A13 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CYP2A13 (canonical) [hepatocarcinogenesis]' SubClassOf 'CYP2A13 (mol)' 'CYP2A13 (canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005085 'CYP2A13 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004866 CYP2A6 (canonical) [hepatocarcinogenesis] 'CYP2A6 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CYP2A6 (canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP2A6' 'CYP2A6 (canonical) [hepatocarcinogenesis]' SubClassOf 'CYP2A6 (mol)' 'CYP2A6 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'CYP2A6 (canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005086 http://purl.obolibrary.org/obo/TXPO_0004867 CYP3A4(canonical) [hepatocarcinogenesis] 'CYP3A4(canonical) [hepatocarcinogenesis]' SubClassOf 'glutathione depletion dependent molecule (canonical)' 'CYP3A4(canonical) [hepatocarcinogenesis]' SubClassOf 'CYP3A4 (mol)' 'CYP3A4(canonical) [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004868 CYP3A5(canonical) [hepatocarcinogenesis] 'CYP3A5(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CYP3A5(canonical) [hepatocarcinogenesis]' SubClassOf 'CYP3A5 (mol)' 'CYP3A5(canonical) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' 'CYP3A5(canonical) [hepatocarcinogenesis]' SubClassOf 'has participant' some http://purl.obolibrary.org/obo/TXPO_0005137 'CYP3A5(canonical) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'CYP3A4(canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004861 aflatoxin B1 [hepatocarcinogenesis] 'aflatoxin B1 [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'aflatoxin B1 [hepatocarcinogenesis]' SubClassOf 'aflatoxin B1' 'aflatoxin B1 [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005081 'aflatoxin B1 [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004862 aflatoxin metabolic process [hepatocarcinogenesis] 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumor suppressor gene mutation [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP1A2(canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP3A4(canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has input' some 'aflatoxin B1 [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP2A6 (canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'aflatoxin metabolic process' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'Cyp1A1 (canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP3A7 (canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP3A5(canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has agent' some 'CYP2A13 (canonical) [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'has output' some 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005082 'aflatoxin metabolic process [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0004863 aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis] 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' SubClassOf 'aflatoxin B1 exo-8,9-epoxide' 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'aflatoxin B1 exo-8,9-epoxide [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005083 http://purl.obolibrary.org/obo/TXPO_0004864 CYP1A2(canonical) [hepatocarcinogenesis] 'CYP1A2(canonical) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'CYP1A2' 'CYP1A2(canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CYP1A2(canonical) [hepatocarcinogenesis]' SubClassOf 'Cyp1A2 (mol)' 'CYP1A2(canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' 'CYP1A2(canonical) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005084 http://purl.obolibrary.org/obo/TXPO_0004860 decreasing adiponectin level [mitochondrial disorder] 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial respiratory chain abnormality [Mitochondrial disorder]' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'decreasing adiponectin level' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'has participant' some 'Wnt' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'has pathway' some 'decreasing adiponectin level' 'decreasing adiponectin level [mitochondrial disorder]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0004858 acetyl-CoA biosynthetic process 'acetyl-CoA biosynthetic process' SubClassOf 'has output' some 'ketone body' 'acetyl-CoA biosynthetic process' SubClassOf 'generating substance' 'acetyl-CoA biosynthetic process' SubClassOf 'has role' some 'growth factor role' 'acetyl-CoA biosynthetic process' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'acetyl-CoA biosynthetic process' SubClassOf 'has role' some 'ligand' 'acetyl-CoA biosynthetic process' SubClassOf 'VEGF (mol)' http://purl.obolibrary.org/obo/TXPO_0004859 decreasing adiponectin level 'decreasing adiponectin level' SubClassOf 'decreasing quantity' 'decreasing adiponectin level' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004854 cancer stem-like cell proliferation 'cancer stem-like cell proliferation' SubClassOf 'cell proliferation' 'cancer stem-like cell proliferation' SubClassOf 'has output' some (('cell' and ('has quality' some 'neoplastic (quality)')) and ('has quality' some 'increased number (quality)')) 'cancer stem-like cell proliferation' SubClassOf 'has result' some 'Hyperfunction of CYP2E1 gene expression' 'cancer stem-like cell proliferation' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'cancer stem-like cell proliferation' SubClassOf 'has result' some 'APC signal transduction pathway' 'cancer stem-like cell proliferation' SubClassOf 'NRAS (mouse) [hepatocarcinogenesis]' 'cancer stem-like cell proliferation' SubClassOf 'has output' some 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' 'cancer stem-like cell proliferation' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004855 Cancer-stem like cell proliferation [hepatocarcinogenesis] 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'has output' some (('cell' and ('has quality' some 'neoplastic (quality)')) and ('has quality' some 'increased number (quality)')) 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'cancer stem-like cell proliferation' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'UHRF1 (predicted)(human) [hepatocarcinogenesis]' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'has quality' some 'inactive' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'UHRF1' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'Cancer-stem like cell proliferation [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' http://purl.obolibrary.org/obo/TXPO_0004856 Tumor suppressor gene mutation 'Tumor suppressor gene mutation' SubClassOf 'mutation' 'Tumor suppressor gene mutation' SubClassOf 'increasing quantity' 'Tumor suppressor gene mutation' SubClassOf 'has output' some 'AGGF1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004857 negative regulation of actin cytoskeleton organization 'negative regulation of actin cytoskeleton organization' SubClassOf 'negative regulation process' 'negative regulation of actin cytoskeleton organization' SubClassOf 'negatively regulates' some 'actin cytoskeleton organization and biogenesis' 'negative regulation of actin cytoskeleton organization' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'negative regulation of actin cytoskeleton organization' SubClassOf 'VEGF (mol)' 'negative regulation of actin cytoskeleton organization' SubClassOf 'has role' some 'ligand' 'negative regulation of actin cytoskeleton organization' SubClassOf 'has role' some 'growth factor role' http://purl.obolibrary.org/obo/TXPO_0004850 4-(phenylazo)aniline [hepatocarcinogenesis] '4-(phenylazo)aniline [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '4-(phenylazo)aniline [hepatocarcinogenesis]' SubClassOf '4-(phenylazo)aniline' '4-(phenylazo)aniline [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' '4-(phenylazo)aniline [hepatocarcinogenesis]' SubClassOf 'molecular complex' http://purl.obolibrary.org/obo/TXPO_0004851 HRAS (mouse) [hepatocarcinogenesis] 'HRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'HRAS (mol)' 'HRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'HRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'HRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'EPCR signaling (primitive)' http://purl.obolibrary.org/obo/TXPO_0004852 KRAS (mouse) [hepatocarcinogenesis] 'KRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'KRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'KRAS (mol)' 'KRAS (mouse) [hepatocarcinogenesis]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005136 'KRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0004853 NRAS (mouse) [hepatocarcinogenesis] 'NRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'NRAS (mol)' 'NRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'NRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'inactivation' 'NRAS (mouse) [hepatocarcinogenesis]' SubClassOf 'has output' some ('UHRF1 (mol)' and ('has quality' some 'inactive')) http://purl.obolibrary.org/obo/TXPO_0004847 mitochondria morphology change 'mitochondria morphology change' SubClassOf 'changing shape' 'mitochondria morphology change' SubClassOf 'liver carcinogenesis dependent process' 'mitochondria morphology change' SubClassOf 'has participant' some '7,12-dimethyltetraphene [hepatocarcinogenesis]' 'mitochondria morphology change' SubClassOf 'has pathway' some 'MIR150 (human) [hepatocarcinogenesis]' 'mitochondria morphology change' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'mitochondria morphology change' SubClassOf 'proto-oncogene mutation' http://purl.obolibrary.org/obo/TXPO_0004848 proto-oncogene mutation 'proto-oncogene mutation' SubClassOf 'mutation' 'proto-oncogene mutation' SubClassOf 'has pathway' some 'MIR150 (human) [hepatocarcinogenesis]' 'proto-oncogene mutation' SubClassOf 'signaling [biological] (primitive)' 'proto-oncogene mutation' SubClassOf 'has participant' some 'TWIST1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004849 7,12-dimethyltetraphene [hepatocarcinogenesis] '7,12-dimethyltetraphene [hepatocarcinogenesis]' SubClassOf '7,12-dimethyltetraphene' '7,12-dimethyltetraphene [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '7,12-dimethyltetraphene [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule' '7,12-dimethyltetraphene [hepatocarcinogenesis]' SubClassOf 'TWIST1 (mol)' http://purl.obolibrary.org/obo/TXPO_0004843 inducible nitric oxide synthase production 'inducible nitric oxide synthase production' SubClassOf 'enzyme production' 'inducible nitric oxide synthase production' SubClassOf 'USP7 (mol)' 'inducible nitric oxide synthase production' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005079 http://purl.obolibrary.org/obo/TXPO_0004844 NOS2 (canonical) [mitochondrial disorder] 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'NOS2 (mol)' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'ACSL4 (mol)' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Increasing CXCR4 level' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'Src (human) [hepatocarcinogenesis]' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'NOS2 (canonical) [mitochondrial disorder]' SubClassOf 'negatively regulates' some 'actin cytoskeleton organization and biogenesis' http://purl.obolibrary.org/obo/TXPO_0004845 Decreasing miR-150 level 'Decreasing miR-150 level' SubClassOf 'decreasing quantity' 'Decreasing miR-150 level' SubClassOf 'has input' some 'MIR150' 'Decreasing miR-150 level' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Decreasing miR-150 level' SubClassOf 'has result' some 'Increasing CXCR4 level' 'Decreasing miR-150 level' SubClassOf 'negative regulation of adherens junction assembly' 'Decreasing miR-150 level' SubClassOf 'has result' some 'EGFR(human) [hepatocarcinogenesis]' 'Decreasing miR-150 level' SubClassOf 'has result' some 'ACSL4 (mol)' 'Decreasing miR-150 level' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0004846 MIR150 (human) [hepatocarcinogenesis] 'MIR150 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'MIR150 (human) [hepatocarcinogenesis]' SubClassOf 'MIR150' 'MIR150 (human) [hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004840 induction of genomic instability [hepatocarcinogenesis] 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'induction of genomic instability' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'cytoplasmic sequestering of cyclin A' 'induction of genomic instability [hepatocarcinogenesis]' SubClassOf 'negative regulation of signaling' http://purl.obolibrary.org/obo/TXPO_0004841 Malfunctioning of centrosome duplication [hepatocarcinogenesis] 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'malfunctioning of centrosome duplication' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'cytoplasmic sequestering of cyclin A [hepatocarcinogenesis]' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has participant' some 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has result' some 'NOS2 (canonical) [mitochondrial disorder]' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has participant' some 'inducible nitric oxide synthase production' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has result' some 'Decreasing miR-150 level' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'has participant' some 'ORC1 - inactive form (human) [hepatocarcinogenesis]' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'negatively regulates' some 'cytoplasmic sequestering of cyclin A' 'Malfunctioning of centrosome duplication [hepatocarcinogenesis]' SubClassOf 'induction of genomic instability [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0004842 Malfunctioning of cytokinesis [hepatocarcinogenesis] 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'malfunctioning of cytokinesis' 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'has result' some 'tumorigenesis [hepatocarcinogenesis]' 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'TGFA (mol)' 'Malfunctioning of cytokinesis [hepatocarcinogenesis]' SubClassOf 'USP7 (mol)' http://purl.obolibrary.org/obo/TXPO_0001488 inflammatory response [Phospholipidosis (excessive defense)] 'inflammatory response [Phospholipidosis (excessive defense)]' SubClassOf 'has participant' some 'PLA2G2E (human)positively regulator of immune response[Phospholipidosis]' http://purl.obolibrary.org/obo/TXPO_0001482 sphingomyelin metabolism imbalance [Niemann Pick Disease Type A] 'sphingomyelin metabolism imbalance [Niemann Pick Disease Type A]' SubClassOf 'has state' some http://purl.obolibrary.org/obo/TXPO_0002327 http://purl.obolibrary.org/obo/TXPO_0005073 release of inflammatory DAMPs 'release of inflammatory DAMPs' SubClassOf 'moving A to the outside of B' 'release of inflammatory DAMPs' SubClassOf 'occurs in' some 'mitochondrion' 'release of inflammatory DAMPs' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005074 'release of inflammatory DAMPs' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0005070 USP7 (mol) 'USP7 (mol)' SubClassOf 'molecule' 'USP7 (mol)' SubClassOf 'liver cancer dependent molecule' 'USP7 (mol)' SubClassOf 'is entity in organism' some 'rattus' http://purl.obolibrary.org/obo/TXPO_0005072 bis(2-ethylhexyl) phthalate [hepatocarcinogenesis] 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'bis(2-ethylhexyl) phthalate' 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule' 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'relateds assay' some 'in vitro assay' 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'is entity in organism' some 'mus musculus' http://purl.obolibrary.org/obo/TXPO_0005071 YAP1 (mol) 'YAP1 (mol)' SubClassOf 'molecule' 'YAP1 (mol)' SubClassOf 'CAR (mol)' 'YAP1 (mol)' SubClassOf 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005067 TERT (mol) 'TERT (mol)' SubClassOf 'molecule' 'TERT (mol)' SubClassOf 'has related human gene' some 'ATF4' 'TERT (mol)' SubClassOf 'family of' some 'ATF' 'TERT (mol)' SubClassOf 'has role' some 'transcription regulator' 'TERT (mol)' SubClassOf 'ATF4 (mol)' 'TERT (mol)' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005066 SNAI1 (mol) 'SNAI1 (mol)' SubClassOf 'molecule' 'SNAI1 (mol)' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'SNAI1 (mol)' SubClassOf 'AMPK (mol)' 'SNAI1 (mol)' SubClassOf 'family of' some 'AMPK (mol)' http://purl.obolibrary.org/obo/TXPO_0005063 PPARGC1A (mol) 'PPARGC1A (mol)' SubClassOf 'molecule' 'PPARGC1A (mol)' SubClassOf 'relateds assay' some 'in vitro assay' 'PPARGC1A (mol)' SubClassOf 'liver cancer dependent molecule' http://purl.obolibrary.org/obo/TXPO_0005062 PPARA(mouse) [hepatocarcinogenesis] 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf 'PPARA (mol)' 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf 'CDK1 inactivation' 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf '1-hydroxyanthraquinone' http://purl.obolibrary.org/obo/TXPO_0005065 SFRP1 (human) [hepatocarcinogenesis] 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'SFRP1 (mol)' 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'has pathway' some 'PROM1 - activation state (human)[hepatocarcinogenesis]' 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'AGGF1 (mol)' 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'signaling [biological] (primitive)' http://purl.obolibrary.org/obo/TXPO_0005064 PROM1 - activation state (human)[hepatocarcinogenesis] 'PROM1 - activation state (human)[hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PROM1 - activation state (human)[hepatocarcinogenesis]' SubClassOf 'PROM1 (human) [hepatocarcinogenesis]' 'PROM1 - activation state (human)[hepatocarcinogenesis]' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0005061 PHB (human) [hepatocarcinogenesis] 'PHB (human) [hepatocarcinogenesis]' SubClassOf 'PHB (mol)' 'PHB (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PHB (human) [hepatocarcinogenesis]' SubClassOf 'hypofunction of hormone metabolic process' http://purl.obolibrary.org/obo/TXPO_0005060 PCK1 - inactive form (predicted)(human) [mitochondrial damage] 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has related human gene' some 'PCK1' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'predicted (quality)' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'PCK1 (predicted)(human) [mitochondrial damage]' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'inactive' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf '1,2-dichloropropane' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0005059 PCK1 (human) [Hepatocarcinogenesis] 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'PCK1 (mol)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PCK1' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'lipid' http://purl.obolibrary.org/obo/TXPO_0005056 NOS2 (mol) 'NOS2 (mol)' SubClassOf 'molecule' 'NOS2 (mol)' SubClassOf 'increasing lipid' http://purl.obolibrary.org/obo/TXPO_0005055 NDUFV3 inactovation [mitochondrial disorder] 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFV3 - inactive form (human)[mitochondrial disorder]' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'NDUFV3 inactivation' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'NDUFV3 - inactive form (human)[mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005058 ORC1 (human) [hepatocarcinogenesis] 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'ORC1 (mol)' 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'PCK1 (human) [Hepatocarcinogenesis]' 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'mitochondria disorder dependent chemical compound' http://purl.obolibrary.org/obo/TXPO_0005057 NRF2(canonical) [mitochondrial disorder] 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'NRF2 (mol)' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'phospholipid peroxidation [mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'increasing leptin level [mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has output' some 'ORC1 (human) [hepatocarcinogenesis]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'NOS2 (mol)' http://purl.obolibrary.org/obo/TXPO_0005052 NDUFV1 inactivation [mitochondrial disorder] 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFV1 - inactive form (human)[mitochondrial disorder]' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'NDUFV1 inactivation' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0005051 NDUFV1 - inactive form (human)[mitochondrial disorder] 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'liver carcinogenesis dependent process' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has part' some 'UHRF1 production' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has part' some 'LDLRAD4 gene promoter methylation [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005054 NDUFV3 - inactive form (human)[mitochondrial disorder] 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFV3 (human) [mitochondrial disorder]' 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0005053 NDUFV3 (human) [mitochondrial disorder] 'NDUFV3 (human) [mitochondrial disorder]' SubClassOf 'NDUFV3 (mol)' 'NDUFV3 (human) [mitochondrial disorder]' SubClassOf 'dysfunctioning of' some 'heme biosynthetic process' 'NDUFV3 (human) [mitochondrial disorder]' SubClassOf 'hypofunction of biosynthesis' http://purl.obolibrary.org/obo/TXPO_0005050 NDUFV1 (human) [mitochondrial disorder] 'NDUFV1 (human) [mitochondrial disorder]' SubClassOf 'NDUFV1 (mol)' 'NDUFV1 (human) [mitochondrial disorder]' SubClassOf 'metabolic dysfunction' http://purl.obolibrary.org/obo/TXPO_0005009 AMPK(canonical) [mitochondrial disorder] 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'AMPK (mol)' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'family of' some 'AMPK (mol)' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'has result' some 'positive regulation of mitochondrial membrane permeability [Mitochondrial disorder]' 'AMPK(canonical) [mitochondrial disorder]' SubClassOf 'disruption of ER-mitochondria contact sites' http://purl.obolibrary.org/obo/TXPO_0005008 AGGF1 signal (primitive) 'AGGF1 signal (primitive)' SubClassOf 'has pathway' some 'AGGF1 signal transduction pathway' 'AGGF1 signal (primitive)' SubClassOf 'has participant' some 'AGGF1 (mol)' 'AGGF1 signal (primitive)' SubClassOf 'signaling [biological] (primitive)' 'AGGF1 signal (primitive)' SubClassOf 'Monuron' 'AGGF1 signal (primitive)' SubClassOf 'CDK1 inactivation' http://purl.obolibrary.org/obo/TXPO_0005005 1-hydroxyanthraquinone '1-hydroxyanthraquinone' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '1-hydroxyanthraquinone' SubClassOf '1-hydroxyanthraquinone' '1-hydroxyanthraquinone' SubClassOf 'negatively regulates' some 'methionine metabolic process' '1-hydroxyanthraquinone' SubClassOf 'liver carcinogenesis dependent process' '1-hydroxyanthraquinone' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' '1-hydroxyanthraquinone' SubClassOf 'Hypofunction of 17β-Estradiol metabolic process' '1-hydroxyanthraquinone' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' '1-hydroxyanthraquinone' SubClassOf 'has participant' some 'liver cancer dependent molecule (canonical)' '1-hydroxyanthraquinone' SubClassOf 'has participant' some 'positive regulation of cell cycle [hepatocarcinogenesis]' '1-hydroxyanthraquinone' SubClassOf 'has participant' some 'AGGF1 signal transduction pathway' http://purl.obolibrary.org/obo/TXPO_0005004 Hypofunction of 17β-Estradiol metabolic process 'Hypofunction of 17β-Estradiol metabolic process' SubClassOf 'hypofunction of hormone metabolic process' 'Hypofunction of 17β-Estradiol metabolic process' SubClassOf 'negative regulation process' 'Hypofunction of 17β-Estradiol metabolic process' SubClassOf 'negatively regulates' some 'methionine metabolic process' http://purl.obolibrary.org/obo/TXPO_0005007 AGGF1 signal transduction pathway 'AGGF1 signal transduction pathway' SubClassOf 'signaling pathway' 'AGGF1 signal transduction pathway' SubClassOf 'USP7 (mol)' 'AGGF1 signal transduction pathway' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005103 http://purl.obolibrary.org/obo/TXPO_0005006 liver cancer dependent molecule (canonical) 'liver cancer dependent molecule (canonical)' SubClassOf 'liver cancer dependent molecule' 'liver cancer dependent molecule (canonical)' SubClassOf 'relateds assay' some 'in vitro assay' 'liver cancer dependent molecule (canonical)' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'liver cancer dependent molecule (canonical)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005103 http://purl.obolibrary.org/obo/TXPO_0005001 saturated fatty acid [mitochondrial disorder] 'saturated fatty acid [mitochondrial disorder]' SubClassOf 'saturated fatty acid' 'saturated fatty acid [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'saturated fatty acid [mitochondrial disorder]' SubClassOf 'activating' http://purl.obolibrary.org/obo/TXPO_0005000 Increasing saturated fatty acid level [mitochondrial disorder] 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of respiratory complex proteins synthesis' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'reactive oxygen species biosynthetic process [Mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondrial dysfunction [Mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'diacylglycerol accumulation [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has output' some 'saturated fatty acid [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'increasing saturated fatty acid level' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'has result' some 'ceramide accumulation [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'manifests phenotype' some 'NDUFA12 (human) [mitochondrial disorder]' 'Increasing saturated fatty acid level [mitochondrial disorder]' SubClassOf 'changing membrane potential' http://purl.obolibrary.org/obo/TXPO_0005003 1,2-dichloropropane [hepatocarcinogenesis] '1,2-dichloropropane [hepatocarcinogenesis]' SubClassOf '1,2-dichloropropane' '1,2-dichloropropane [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' '1,2-dichloropropane [hepatocarcinogenesis]' SubClassOf 'MMP9 (mol)' '1,2-dichloropropane [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0005002 saturated fatty acid 'saturated fatty acid' SubClassOf 'lipid' 'saturated fatty acid' SubClassOf 'MMP2 (mol)' 'saturated fatty acid' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0005049 NDUFS2 inactivation [mitochondrial disorder] 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'NDUFS2 inactivaiton' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFS2 - inactive form (human)[mitochondrial disorder]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'PPARGC1A (mol)' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'p53 (mol)' http://purl.obolibrary.org/obo/TXPO_0005048 NDUFS2 - inactive form (human)[mitochondrial disorder] 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFS2 (human) [mitochondrial disorder]' 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'protein production' http://purl.obolibrary.org/obo/TXPO_0005045 NDUFB6 - inactive form (human)[mitochondrial disorder] 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFB6 (human) [mitochondrial disorder]' 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'cell migration' http://purl.obolibrary.org/obo/TXPO_0005044 NDUFB6 (human) [mitochondrial disorder] 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'NDUFB6 (mol)' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has result' some 'ATP depletion [Mitochondrial disorder]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'NDUFA12 - inactive form (human)[mitochondrial disorder]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has result' some 'mitochondria morphology change [mitochondrial disorder]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has result' some 'decreasing mitochondrial membrane potential [Mitochondrial disorder]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has result' some 'lipid storage in liver [Mitochondrial disorder]' 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'has result' some 'increasing demand for response to oxidative stress [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005047 NDUFS2 (human) [mitochondrial disorder] 'NDUFS2 (human) [mitochondrial disorder]' SubClassOf 'NDUFS2 (mol)' 'NDUFS2 (human) [mitochondrial disorder]' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005096 'NDUFS2 (human) [mitochondrial disorder]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0005046 NDUFB6 inactivation [mitochondrial disorder] 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'NDUFB6 inactivation' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFB6 - inactive form (human)[mitochondrial disorder]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'biological structure formation' http://purl.obolibrary.org/obo/TXPO_0005041 NDUFA12 (human) [mitochondrial disorder] 'NDUFA12 (human) [mitochondrial disorder]' SubClassOf 'NDUFA12 (mol)' 'NDUFA12 (human) [mitochondrial disorder]' SubClassOf 'membrane potential' 'NDUFA12 (human) [mitochondrial disorder]' SubClassOf 'electric potential attribute' and ('has attribute value' some 'large (value)') http://purl.obolibrary.org/obo/TXPO_0005040 MTAP (mol) 'MTAP (mol)' SubClassOf 'molecule' 'MTAP (mol)' SubClassOf 'changing quality' http://purl.obolibrary.org/obo/TXPO_0005043 NDUFA12 inactivation [mitochondrial disorder] 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'NDUFA12 inactivation' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFA12 - inactive form (human)[mitochondrial disorder]' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'increasing concentration' http://purl.obolibrary.org/obo/TXPO_0005042 NDUFA12 - inactive form (human)[mitochondrial disorder] 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFA12 (human) [mitochondrial disorder]' 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFA12 inactivation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005038 IGFBP3 (human) [hepatocarcinogenesis] 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'IGFBP3 (mol)' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'TNF signaling [mitochondrial disorder]' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'increasing lipid' http://purl.obolibrary.org/obo/TXPO_0005037 STK3 (mol) 'STK3 (mol)' SubClassOf 'molecule' 'STK3 (mol)' SubClassOf 'tissue regeneration' http://purl.obolibrary.org/obo/TXPO_0005039 KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis] 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'KIAA0101' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'mitochondrial disorder dependent process' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'NDUFA12 inactivation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005034 HIF1A(canonical) [mitochondrial disorder] 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'HIF1A (mol)' 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'increasing blood glucose level' http://purl.obolibrary.org/obo/TXPO_0005033 HHIP (human) [hepatocarcinogenesis] 'HHIP (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'HHIP (human) [hepatocarcinogenesis]' SubClassOf 'HHIP (mol)' 'HHIP (human) [hepatocarcinogenesis]' SubClassOf 'malfunctioning process' http://purl.obolibrary.org/obo/TXPO_0005036 MST1 (mol) 'MST1 (mol)' SubClassOf 'molecule' 'MST1 (mol)' SubClassOf 'nodule formation' 'MST1 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'MST1 (mol)' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'MST1 (mol)' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0005035 HNF4A (canonical) [hepatocarcinogenesis] 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'HNF4A (mol)' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'UHRF1 - inactive form (predicted)(human) [hepatocarcinogenesis]' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'cellular damage' http://purl.obolibrary.org/obo/TXPO_0005030 FZD9 (mol) 'FZD9 (mol)' SubClassOf 'FZD' 'FZD9 (mol)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0005032 GJB1 (mol) 'GJB1 (mol)' SubClassOf 'molecule' 'GJB1 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'GJB1 (mol)' SubClassOf 'negative regulation of ROS formation' 'GJB1 (mol)' SubClassOf 'has result' some 'ATF6 signaling (primitive) [hepatocarcinogenesis]' 'GJB1 (mol)' SubClassOf 'negatively regulates' some 'reactive oxygen species biosynthetic process' 'GJB1 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0005031 GJA1 (mol) 'GJA1 (mol)' SubClassOf 'molecule' 'GJA1 (mol)' SubClassOf 'has result' some 'Inflammatory response [mitochondrial disorder]' 'GJA1 (mol)' SubClassOf http://purl.obolibrary.org/obo/TXPO_0005139 'GJA1 (mol)' SubClassOf 'has result' some 'increasing demand for response to ER stress [mitochondrial disorder]' 'GJA1 (mol)' SubClassOf 'mitochondrial disorder dependent process' 'GJA1 (mol)' SubClassOf 'occurs in' some 'mitochondrion' 'GJA1 (mol)' SubClassOf 'has result' some 'TLR9 signaling [Mitochondrial disorder]' 'GJA1 (mol)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0005027 FZD5 (mol) 'FZD5 (mol)' SubClassOf 'FZD' 'FZD5 (mol)' SubClassOf 'increasing quantity' 'FZD5 (mol)' SubClassOf 'has output' only 'uric acid' http://purl.obolibrary.org/obo/TXPO_0005026 FZD2 (mol) 'FZD2 (mol)' SubClassOf 'FZD' 'FZD2 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'FZD2 (mol)' SubClassOf 'has part' some 'Grp78 signaling (primitive) [hepatocarcinogenesis]' 'FZD2 (mol)' SubClassOf 'response to endoplasmic reticulum stress' 'FZD2 (mol)' SubClassOf 'has part' some 'Negative regulation of ATP transport [mitochondrial disorder]' 'FZD2 (mol)' SubClassOf 'liver carcinogenesis dependent process' http://purl.obolibrary.org/obo/TXPO_0005029 FZD7 (mol) 'FZD7 (mol)' SubClassOf 'FZD' 'FZD7 (mol)' SubClassOf 'negative regulation of enzyme activation' http://purl.obolibrary.org/obo/TXPO_0005028 FZD6 (mol) 'FZD6 (mol)' SubClassOf 'FZD' 'FZD6 (mol)' SubClassOf 'hypofunctioning' 'FZD6 (mol)' SubClassOf 'dysfunctioning of' some http://purl.obolibrary.org/obo/GO_0002418 http://purl.obolibrary.org/obo/TXPO_0005023 EPB41L3 (mol) 'EPB41L3 (mol)' SubClassOf 'molecule' 'EPB41L3 (mol)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0005022 CYP3A7 (mol) 'CYP3A7 (mol)' SubClassOf 'Cyp3' 'CYP3A7 (mol)' SubClassOf 'has related human gene' some 'CYP3A7' 'CYP3A7 (mol)' SubClassOf 'has part' some 'Increasing MYC level' 'CYP3A7 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CYP3A7 (mol)' SubClassOf 'CYP2A6 (mol)' 'CYP3A7 (mol)' SubClassOf 'has part' some 'NDUFS2 inactivaiton' 'CYP3A7 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'CYP3A7 (mol)' SubClassOf 'has part' some 'fumonisin B1 [hepatocarcinogenesis]' 'CYP3A7 (mol)' SubClassOf 'has part' some 'ORC1 inactivation [hepatocarcinogenesis]' 'CYP3A7 (mol)' SubClassOf 'has part' some 'Hypofunction of TFAM gene expression' 'CYP3A7 (mol)' SubClassOf 'has part' some 'HIF1A - activation state (canonical)[mitochondrial disorder]' 'CYP3A7 (mol)' SubClassOf 'has part' some 'MYC gene promoter demethylation [hepatocarcinogenesis]' 'CYP3A7 (mol)' SubClassOf 'has part' some 'Notch 2 (canonical) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005025 FZD1 (mol) 'FZD1 (mol)' SubClassOf 'FZD' 'FZD1 (mol)' SubClassOf '4-hydroxynonenal' 'FZD1 (mol)' SubClassOf 'mitochondria disorder dependent chemical compound' http://purl.obolibrary.org/obo/TXPO_0005024 FOXO1 (canonical)[mitochondrial disorder] 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'FOXO1 (mol)' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'has role' some 'positive regulator of gluconeogenic gene transcription role' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'ground glass appearance dependent molecule (canonical)' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'family of' some 'FOXO1 (mol)' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'reactive aldehyde' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005021 CYP2A6 (mol) 'CYP2A6 (mol)' SubClassOf 'has related human gene' some 'CYP2A6' 'CYP2A6 (mol)' SubClassOf 'Cyp2' 'CYP2A6 (mol)' SubClassOf 'molecular activation' http://purl.obolibrary.org/obo/TXPO_0005020 CYP2A13 (mol) 'CYP2A13 (mol)' SubClassOf 'Cyp2' 'CYP2A13 (mol)' SubClassOf 'has related human gene' some 'CYP2A13' 'CYP2A13 (mol)' SubClassOf 'leukocyte migration' http://purl.obolibrary.org/obo/TXPO_0005019 COX-2 (canonical) [hepatocarcinogenesis] 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'COX-2 (mol)' 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'dysfunctioning of' some http://purl.obolibrary.org/obo/GO_0002418 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'FZD6 (mol)' 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has result' some 'TERT (canonical) [hepatocarcinogenesis]' 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'COX-2 (canonical) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' http://purl.obolibrary.org/obo/TXPO_0005016 CDH1 (canonical) [hepatocarcinogenesis] 'CDH1 (canonical) [hepatocarcinogenesis]' SubClassOf 'CDH1 (mol)' 'CDH1 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'CDH1 (canonical) [hepatocarcinogenesis]' SubClassOf 'Hippo signaling (primitive)' 'CDH1 (canonical) [hepatocarcinogenesis]' SubClassOf 'PPARGC1A (mol)' http://purl.obolibrary.org/obo/TXPO_0005015 liver cancer dependent molecule (mouse in vitro) 'liver cancer dependent molecule (mouse in vitro)' SubClassOf 'liver cancer dependent molecule' 'liver cancer dependent molecule (mouse in vitro)' SubClassOf 'is entity in organism' some 'mus musculus' 'liver cancer dependent molecule (mouse in vitro)' SubClassOf 'malfunctioning process' http://purl.obolibrary.org/obo/TXPO_0005018 CDT1 (human) [hepatocarcinogenesis] 'CDT1 (human) [hepatocarcinogenesis]' SubClassOf 'CDT1 (mol)' 'CDT1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'CDT1 (human) [hepatocarcinogenesis]' SubClassOf 'malfunctioning of controlling' http://purl.obolibrary.org/obo/TXPO_0005017 CDH1 (mol) 'CDH1 (mol)' SubClassOf 'E-cadherin' 'CDH1 (mol)' SubClassOf 'has result' some 'Decreasing GPHN level' 'CDH1 (mol)' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CDH1 (mol)' SubClassOf 'liver carcinogenesis dependent process' 'CDH1 (mol)' SubClassOf 'has result' some 'Increasing PROX1 level' 'CDH1 (mol)' SubClassOf 'has result' some 'cancer stem-like cell proliferation' 'CDH1 (mol)' SubClassOf 'hypoxia' 'CDH1 (mol)' SubClassOf 'has result' some 'FZD5 (canonical) [hepatocarcinogenesis]' 'CDH1 (mol)' SubClassOf 'has result' some 'negative regulation of activation' 'CDH1 (mol)' SubClassOf 'has result' some 'Increasing JUN level [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005012 CADM1 (mol) 'CADM1 (mol)' SubClassOf 'molecule' 'CADM1 (mol)' SubClassOf 'increasing quantity' http://purl.obolibrary.org/obo/TXPO_0005011 BECN1 (mol) 'BECN1 (mol)' SubClassOf 'molecule' 'BECN1 (mol)' SubClassOf 'changing state' http://purl.obolibrary.org/obo/TXPO_0005014 CAR (mouse) [hepatocarcinogenesis] 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'CAR (mol)' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'has part' some 'Increasing CXCR4 level' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'MTAP (mol)' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'CAR (mouse) [hepatocarcinogenesis]' SubClassOf 'has part' some 'ACSL4 (mol)' http://purl.obolibrary.org/obo/TXPO_0005013 liver cancer dependent molecule (rat) 'liver cancer dependent molecule (rat)' SubClassOf 'is entity in organism' some 'rattus' 'liver cancer dependent molecule (rat)' SubClassOf 'liver cancer dependent molecule' 'liver cancer dependent molecule (rat)' SubClassOf 'mitochondrial disorder dependent process' 'liver cancer dependent molecule (rat)' SubClassOf 'CADM1 (mol)' 'liver cancer dependent molecule (rat)' SubClassOf 'has result' some 'PPARalpha activation [Mitochondrial disorder]' 'liver cancer dependent molecule (rat)' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0005010 ATF4(human) [hepatocarcinogenesis] 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'ATF4' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has role' some 'transcription regulator' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'ATF4 (mol)' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'family of' some 'ATF' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'liver carcinogenesis dependent process' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has context' only 'hepatocarcinogenesis [toxic course]' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'ORC1 - inactive form (human) [hepatocarcinogenesis]' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has output' some 'negative regulation of DNA repair [hepatocarcinogenesis]' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has result' some 'chemokine (C-X-C motif) ligand 8 production [hepatocarcinogenesis]' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'has participant' some 'EGFR signaling (primitive) [hepatocarcinogenesis]' 'ATF4(human) [hepatocarcinogenesis]' SubClassOf 'lipoperoxidation' http://purl.obolibrary.org/obo/TXPO_0000279 toxicological imbalance L 'toxicological imbalance L' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological imbalance L' SubClassOf 'toxicological imbalance' http://purl.obolibrary.org/obo/TXPO_0001261 hypofunction of phospholipid export from lysosome 'hypofunction of phospholipid export from lysosome' SubClassOf 'dysfunctioning of' some 'phospholipid transport from lysosome into cytosol' http://purl.obolibrary.org/obo/TXPO_0001208 toxicological imbalance MVL 'toxicological imbalance MVL' SubClassOf 'toxicological imbalance' 'toxicological imbalance MVL' SubClassOf 'toxicological imbalance VL (toxic action)' http://purl.obolibrary.org/obo/TXPO_0003985 phospholipid homeostasis imbalance [Phospholipidosis - genetic] 'phospholipid homeostasis imbalance [Phospholipidosis - genetic]' SubClassOf 'has state' some ('toxicological imbalance SM' or http://purl.obolibrary.org/obo/TXPO_0002327) http://purl.obolibrary.org/obo/TXPO_0003986 sphingomyelin homeostasis imbalance [Niemann Pick Disease Type A] 'sphingomyelin homeostasis imbalance [Niemann Pick Disease Type A]' SubClassOf 'has state' some http://purl.obolibrary.org/obo/TXPO_0002327 http://purl.obolibrary.org/obo/TXPO_0003992 toxicological imbalance 'toxicological imbalance' SubClassOf 'has output' some http://www.w3.org/2002/07/owl#Thing 'toxicological imbalance' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'functioning performance value')))) 'toxicological imbalance' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'functioning performance value')))) 'toxicological imbalance' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/TXPO_0004208)))) 'toxicological imbalance' SubClassOf 'has part' some ('demand state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some http://purl.obolibrary.org/obo/TXPO_0004208)))) http://purl.obolibrary.org/obo/GO_0002418 immune response to tumor cell 'immune response to tumor cell' SubClassOf 'immune response' http://purl.obolibrary.org/obo/GO_0070498 IL-1 signal transduction pathway 'IL-1 signal transduction pathway' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004208 degree level 'degree level' SubClassOf 'qualitative quantity' http://purl.obolibrary.org/obo/TXPO_0005129 PROM1 - activation state (human)[hepatocarcinogenesis] 'PROM1 - activation state (human)[hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PROM1 - activation state (human)[hepatocarcinogenesis]' SubClassOf 'PROM1 (human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005126 PPARA(mouse) [hepatocarcinogenesis] 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf 'PPARA (mol)' 'PPARA(mouse) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (mouse in vitro)' http://purl.obolibrary.org/obo/TXPO_0005125 PPARA(canonical) [mitochondrial disorder] 'PPARA(canonical) [mitochondrial disorder]' SubClassOf 'PPARA (mol)' 'PPARA(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0005128 PROCR (mol) 'PROCR (mol)' SubClassOf 'molecule' 'PROCR (mol)' SubClassOf 'has related human gene' some 'ABHD1' http://purl.obolibrary.org/obo/TXPO_0005127 PPARGC1A (mol) 'PPARGC1A (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005122 PCK1 (human) [Hepatocarcinogenesis] 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'PCK1 (mol)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'PCK1 (human) [Hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'PCK1' http://purl.obolibrary.org/obo/TXPO_0005121 ORC1 (human) [hepatocarcinogenesis] 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'ORC1 (human) [hepatocarcinogenesis]' SubClassOf 'ORC1 (mol)' http://purl.obolibrary.org/obo/TXPO_0005124 PHB (human) [hepatocarcinogenesis] 'PHB (human) [hepatocarcinogenesis]' SubClassOf 'PHB (mol)' 'PHB (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005123 PCK1 - inactive form (predicted)(human) [mitochondrial damage] 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has related human gene' some 'PCK1' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'predicted (quality)' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'PCK1 (predicted)(human) [mitochondrial damage]' 'PCK1 - inactive form (predicted)(human) [mitochondrial damage]' SubClassOf 'has quality' some 'inactive' http://purl.obolibrary.org/obo/TXPO_0005120 NRF2(canonical) [mitochondrial disorder] 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'NRF2 (mol)' 'NRF2(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0005119 NOS2 (mol) 'NOS2 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005118 NDUFV3 inactovation [mitochondrial disorder] 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFV3 - inactive form (human)[mitochondrial disorder]' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'NDUFV3 inactivation' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFV3 inactovation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' http://purl.obolibrary.org/obo/TXPO_0005115 NDUFV1 inactivation [mitochondrial disorder] 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFV1 - inactive form (human)[mitochondrial disorder]' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'NDUFV1 inactivation' 'NDUFV1 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005114 NDUFV1 - inactive form (human)[mitochondrial disorder] 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFV1 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFV1 (human) [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005117 NDUFV3 - inactive form (human)[mitochondrial disorder] 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFV3 (human) [mitochondrial disorder]' 'NDUFV3 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005116 NDUFV3 (human) [mitochondrial disorder] 'NDUFV3 (human) [mitochondrial disorder]' SubClassOf 'NDUFV3 (mol)' http://purl.obolibrary.org/obo/TXPO_0005111 NDUFS2 - inactive form (human)[mitochondrial disorder] 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFS2 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFS2 (human) [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005110 NDUFS2 (human) [mitochondrial disorder] 'NDUFS2 (human) [mitochondrial disorder]' SubClassOf 'NDUFS2 (mol)' http://purl.obolibrary.org/obo/TXPO_0005113 NDUFV1 (human) [mitochondrial disorder] 'NDUFV1 (human) [mitochondrial disorder]' SubClassOf 'NDUFV1 (mol)' http://purl.obolibrary.org/obo/TXPO_0005112 NDUFS2 inactivation [mitochondrial disorder] 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'NDUFS2 inactivaiton' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFS2 - inactive form (human)[mitochondrial disorder]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFS2 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0005108 NDUFB6 - inactive form (human)[mitochondrial disorder] 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFB6 (human) [mitochondrial disorder]' 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFB6 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005107 NDUFB6 (human) [mitochondrial disorder] 'NDUFB6 (human) [mitochondrial disorder]' SubClassOf 'NDUFB6 (mol)' http://purl.obolibrary.org/obo/TXPO_0005109 NDUFB6 inactivation [mitochondrial disorder] 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'NDUFB6 inactivation' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFB6 - inactive form (human)[mitochondrial disorder]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFB6 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' http://purl.obolibrary.org/obo/TXPO_0005104 NDUFA12 (human) [mitochondrial disorder] 'NDUFA12 (human) [mitochondrial disorder]' SubClassOf 'NDUFA12 (mol)' http://purl.obolibrary.org/obo/TXPO_0005103 MTAP (mol) 'MTAP (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005106 NDUFA12 inactivation [mitochondrial disorder] 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has result' some 'Negative regulation of mitochondrial respiratory chain complex I subunit phosphorylation [mitochondrial disorder]' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'mitochondrial disorder dependent process' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'NDUFA12 inactivation' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has context' only 'mitochondrial damage [toxic course]' 'NDUFA12 inactivation [mitochondrial disorder]' SubClassOf 'has output' some 'NDUFA12 - inactive form (human)[mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005105 NDUFA12 - inactive form (human)[mitochondrial disorder] 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (human in vitro)' 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'has quality' some 'inactive' 'NDUFA12 - inactive form (human)[mitochondrial disorder]' SubClassOf 'NDUFA12 (human) [mitochondrial disorder]' http://purl.obolibrary.org/obo/TXPO_0005100 MSH2 (mol) 'MSH2 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005102 MSH6 (mol) 'MSH6 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005101 MSH6 (canonical) [hepatocarcinogenesis] 'MSH6 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'MSH6 (canonical) [hepatocarcinogenesis]' SubClassOf 'MSH6 (mol)' http://purl.obolibrary.org/obo/TXPO_0005137 YAP1 (mol) 'YAP1 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005136 USP7 (mol) 'USP7 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005139 release of inflammatory DAMPs 'release of inflammatory DAMPs' SubClassOf 'moving A to the outside of B' 'release of inflammatory DAMPs' SubClassOf 'occurs in' some 'mitochondrion' http://purl.obolibrary.org/obo/TXPO_0005138 bis(2-ethylhexyl) phthalate [hepatocarcinogenesis] 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'bis(2-ethylhexyl) phthalate' 'bis(2-ethylhexyl) phthalate [hepatocarcinogenesis]' SubClassOf 'hepatocarcinogenesis dependent chemical compound' http://purl.obolibrary.org/obo/TXPO_0005133 TERT (mol) 'TERT (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005132 SNAI1 (mol) 'SNAI1 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005135 TGFA (mol) 'TGFA (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005134 TFAM (mol) 'TFAM (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005131 SFRP1 (human) [hepatocarcinogenesis] 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'SFRP1 (mol)' 'SFRP1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005130 PTK2 (mol) 'PTK2 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/GO_0038151 CCL2 signal transduction pathway 'CCL2 signal transduction pathway' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/PATO_0001024 power 'power' EquivalentTo 'power (attribute)' and ('has attribute value' some 'quality value') 'power' SubClassOf 'quality' http://purl.obolibrary.org/obo/TXPO_0000736 PLA2G2E (mol) 'PLA2G2E (mol)' SubClassOf 'group IIE secretory phospholipase A2' http://purl.obolibrary.org/obo/NCIT_C49508 high level 'high level' SubClassOf 'degree level' http://purl.obolibrary.org/obo/TXPO_0002327 toxicological imbalance VL(defense) 'toxicological imbalance VL(defense)' SubClassOf 'has part' some 'imbalance state' 'toxicological imbalance VL(defense)' SubClassOf 'has part' some ('state of functional supply' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'very low level')))) 'toxicological imbalance VL(defense)' SubClassOf 'toxicological imbalance' http://purl.obolibrary.org/obo/TXPO_0002328 very low level 'very low level' SubClassOf 'degree level' http://purl.obolibrary.org/obo/TXPO_0003651 phospholipid metabolism balance [Phospholipidosis (adaptation2)] 'phospholipid metabolism balance [Phospholipidosis (adaptation2)]' SubClassOf 'has context' only 'phospholipidosis (toxic course)' 'phospholipid metabolism balance [Phospholipidosis (adaptation2)]' SubClassOf 'phospholipid metabolism balance' 'phospholipid metabolism balance [Phospholipidosis (adaptation2)]' SubClassOf 'has state' some 'toxicological balance L=L (maintining homeostasis)' http://purl.obolibrary.org/obo/GO_0031532 actin cytoskeleton reorganization 'actin cytoskeleton reorganization' SubClassOf 'actin cytoskeleton organization and biogenesis' http://purl.obolibrary.org/obo/TXPO_0005089 HHIP (human) [hepatocarcinogenesis] 'HHIP (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'HHIP (human) [hepatocarcinogenesis]' SubClassOf 'HHIP (mol)' http://purl.obolibrary.org/obo/TXPO_0005088 GJB1 (mol) 'GJB1 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005085 FZD7 (mol) 'FZD7 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005084 FZD6 (mol) 'FZD6 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005087 GJA1 (mol) 'GJA1 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005086 FZD9 (mol) 'FZD9 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005081 FZD1 (mol) 'FZD1 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005080 FOXO1 (canonical)[mitochondrial disorder] 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'FOXO1 (mol)' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'has role' some 'positive regulator of gluconeogenic gene transcription role' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'family of' some 'FOXO1 (mol)' 'FOXO1 (canonical)[mitochondrial disorder]' SubClassOf 'ground glass appearance dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0005083 FZD5 (mol) 'FZD5 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005082 FZD2 (mol) 'FZD2 (mol)' SubClassOf 'FZD' http://purl.obolibrary.org/obo/TXPO_0005078 CYP3A7 (mol) 'CYP3A7 (mol)' SubClassOf 'Cyp3' 'CYP3A7 (mol)' SubClassOf 'has related human gene' some 'CYP3A7' http://purl.obolibrary.org/obo/TXPO_0005077 CYP2A6 (mol) 'CYP2A6 (mol)' SubClassOf 'has related human gene' some 'CYP2A6' 'CYP2A6 (mol)' SubClassOf 'Cyp2' http://purl.obolibrary.org/obo/TXPO_0005079 EPB41L3 (mol) 'EPB41L3 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005074 CDH1 (mol) 'CDH1 (mol)' SubClassOf 'E-cadherin' http://purl.obolibrary.org/obo/TXPO_0005076 CYP2A13 (mol) 'CYP2A13 (mol)' SubClassOf 'Cyp2' 'CYP2A13 (mol)' SubClassOf 'has related human gene' some 'CYP2A13' http://purl.obolibrary.org/obo/TXPO_0005075 CDT1 (human) [hepatocarcinogenesis] 'CDT1 (human) [hepatocarcinogenesis]' SubClassOf 'CDT1 (mol)' 'CDT1 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' http://purl.obolibrary.org/obo/TXPO_0005099 MSH2 (canonical) [hepatocarcinogenesis] 'MSH2 (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' 'MSH2 (canonical) [hepatocarcinogenesis]' SubClassOf 'MSH2 (mol)' http://purl.obolibrary.org/obo/TXPO_0005096 KDR (mol) 'KDR (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005095 IGFBP3 (human) [hepatocarcinogenesis] 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'IGFBP3 (human) [hepatocarcinogenesis]' SubClassOf 'IGFBP3 (mol)' http://purl.obolibrary.org/obo/TXPO_0005098 MET (mol) 'MET (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005097 KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis] 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has related human gene' some 'KIAA0101' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'has quality' some 'predicted (quality)' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (human in vitro)' 'KIAA0101 tv2 (predicted)(human) [hepatocarcinogenesis]' SubClassOf 'KIAA0101 (predicted)(human) [hepatocarcinogenesis]' http://purl.obolibrary.org/obo/TXPO_0005092 HOTAIR (mol) 'HOTAIR (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005091 HNF4A (canonical) [hepatocarcinogenesis] 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'HNF4A (mol)' 'HNF4A (canonical) [hepatocarcinogenesis]' SubClassOf 'liver cancer dependent molecule (canonical)' http://purl.obolibrary.org/obo/TXPO_0005094 STK3 (mol) 'STK3 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005093 MST1 (mol) 'MST1 (mol)' SubClassOf 'molecule' http://purl.obolibrary.org/obo/TXPO_0005090 HIF1A(canonical) [mitochondrial disorder] 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'mitochondrial damage dependent molecule (canonical)' 'HIF1A(canonical) [mitochondrial disorder]' SubClassOf 'HIF1A (mol)' http://purl.obolibrary.org/obo/GO_0048012 HGFR signal transduction pathway 'HGFR signal transduction pathway' SubClassOf 'signaling pathway' http://purl.obolibrary.org/obo/TXPO_0001741 large (functioning performance value) 'large (functioning performance value)' SubClassOf 'functioning performance value' http://purl.obolibrary.org/obo/TXPO_0004322 TLR9 signaling pathway [hepatocarcinogenesis] 'TLR9 signaling pathway [hepatocarcinogenesis]' SubClassOf 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004323 interleukin-6-mediated signaling pathway [Mitochondrial disorder] 'interleukin-6-mediated signaling pathway [Mitochondrial disorder]' SubClassOf 'interleukin-6-mediated signaling pathway' http://purl.obolibrary.org/obo/TXPO_0004321 TLR9 signaling pathway [Mitochondrial disorder] 'TLR9 signaling pathway [Mitochondrial disorder]' SubClassOf 'TLR9 signaling pathway' http://purl.obolibrary.org/obo/TXPO_0000279 toxicological imbalance L 'toxicological imbalance L' SubClassOf 'has part' some ('supply state of functioning' and ('has attribute' some ('power (attribute)' and ('has attribute value' some 'large (functioning performance value)')))) 'toxicological imbalance L' SubClassOf 'toxicological imbalance'